Radiotherapy protection system for reducing normal tissue damage

Abstract

The invention belongs to the technical field of medical treatment, and discloses a radiotherapy protection system for reducing normal tissue damage, and the system comprises a real-time imaging and monitoring module which employs high-speed CT or MRI equipment to obtain 4D images of a target region and surrounding tissues of a patient in real time in a treatment process; the dynamic protection dose distribution module is used for dynamically calculating dose distribution of each radiation according to the real-time imaging data, optimizing an irradiation path and reducing the stress of normal tissues; the intelligent feedback control module is used for detecting the accumulated dose of a target region and normal tissues in real time and dynamically adjusting an irradiation strategy; inputting the real-time image and the dose monitoring data into a treatment planning system, and updating an irradiation plan; the user interaction module provides a radiotherapy real-time display interface; patient physiological data is monitored in real time. According to the invention, through dynamic real-time monitoring, dose distribution optimization and intelligent feedback control, the limitation of the traditional radiotherapy technology on real-time performance and protection effect is broken through. The system significantly reduces damage to normal tissues, improves treatment precision and patient experience, and has wide clinical application value.

Description

Technical Field

[0001] The present invention belongs to but is not limited to the field of medical technology, and in particular relates to a radiation therapy protection system for reducing damage to normal tissues. Background Art

[0002] Currently, radiotherapy generally uses a combination of fixed templates and image-guided systems to accurately locate and target radiation doses in the lesion area, thereby reducing damage to surrounding normal tissues. These technologies rely on tools such as computed tomography (CT), magnetic resonance imaging (MRI), and radiation dose optimization algorithms. However, these systems have the following technical bottlenecks:

[0003] Lack of real-time performance: Image registration, which is usually completed before treatment, cannot fully cope with the target area deviation caused by respiratory movement, organ displacement or patient posture changes during treatment;

[0004] Limited protection range: Fixed templates have limitations in protecting normal tissues, and it is difficult to flexibly adjust the boundaries of the protection zone;

[0005] Tissue damage is difficult to avoid: During multiple irradiation sessions, the cumulative dose will inevitably lead to radiation damage to healthy tissues.

[0006] How to use real-time monitoring technology and dynamic dose control methods in radiotherapy to achieve high-precision irradiation of the target area while reducing radiation damage to surrounding normal tissues is an important problem facing existing technologies. Summary of the invention

[0007] In view of the problems existing in the prior art, the present invention provides a radiation therapy protection system for reducing damage to normal tissues.

[0008] The present invention is implemented as follows: a radiation therapy protection system for reducing normal tissue damage, the system comprising:

[0009] Real-time imaging and monitoring module, using high-speed CT or MRI equipment to obtain 4D images of the patient's target area and surrounding tissues in real time during treatment; automatic segmentation of imaging data through artificial intelligence (AI) algorithms to identify the target area and adjacent normal tissues in real time; and use infrared trackers or electronic surface trackers to capture the patient's body surface movement and internal organ displacement in real time;

[0010] The dynamic protection dose distribution module is connected to the real-time imaging and monitoring module. Based on the real-time imaging data, it dynamically calculates the dose distribution of each radiation, optimizes the irradiation path, and reduces the dose to normal tissues. It is equipped with a high-precision collimation system to adjust the shape and intensity of the radiation beam to adapt to the dynamic changes of the target area. It is equipped with a shielding layer with adjustable thickness and shape to protect normal tissues in non-target areas.

[0011] The intelligent feedback control module is connected to the real-time imaging and monitoring module to detect the cumulative dose of the target area and normal tissues in real time and dynamically adjust the irradiation strategy; the real-time imaging and dose monitoring data are input into the treatment planning system to update the irradiation plan;

[0012] The user interaction module is connected to the real-time imaging and monitoring module to provide a real-time display interface for radiotherapy, supporting physicians to intervene in real time to adjust treatment parameters; it monitors the patient's physiological data, such as breathing and heartbeat, in real time and feeds it back to the system.

[0013] Furthermore, the real-time imaging and monitoring module specifically includes:

[0014] High frame rate 4D image acquisition equipment:

[0015] (1) Imaging equipment selection: Use 64-row or higher high-speed CT or superconducting 3T MRI to ensure clear capture of the target area and surrounding tissues during treatment, with an acquisition frame rate of 10-20 frames per second;

[0016] (2) Image preprocessing unit: De-noise and enhance the image during the acquisition process to reduce blur caused by patient movement and improve segmentation accuracy.

[0017] Tissue segmentation and tracking unit:

[0018] (1) AI model library: pre-loaded deep learning models, such as U-Net and ResNet, for automatic segmentation of target areas, such as tumor tissue, and normal tissues, such as nerves and blood vessels.

[0019] (2) Real-time tracking algorithm: Based on the combination of optical flow method and Kalman filter, it can capture the displacement changes of target area and normal tissue under dynamic conditions such as breathing movement and heartbeat;

[0020] Motion Capture System:

[0021] (1) Surface tracking device: Attach markers such as reflective balls or fluorescent markers to the patient's body surface and track the patient's body surface movement through an infrared camera;

[0022] (2) Internal motion compensation: Use a respiratory sensor belt and abdominal pressure sensor to capture the displacement of internal organs and perform real-time correction of image data.

[0023] Furthermore, the dynamic protection dosage distribution module specifically includes:

[0024] Dose Optimization Controller:

[0025] (1) Core algorithm: Based on the Monte Carlo algorithm and dose volume histogram (DVH), the irradiation dose distribution is calculated in real time;

[0026] (2) Dynamic dose adjustment: The intensity and distribution of radiation dose are adjusted according to real-time images to ensure that sufficient dose is provided to the target area while avoiding over-irradiation of normal tissues;

[0027] Multi-leaf collimator MLC:

[0028] (1) Blade control accuracy: Using servo motor control, the accuracy reaches 0.5 mm, achieving precise matching of the target area shape;

[0029] (2) Dynamic reconstruction function: The beam shape can be adjusted according to the real-time deformation of the target area and linked with the dose optimization controller;

[0030] Electronic shielding device:

[0031] (1) Material selection: Use high atomic number materials with variable thickness, such as tungsten alloys, combined with flexible polymer layers to achieve shielding;

[0032] (2) Shape adjustment: Equipped with a micro electric drive to automatically adjust the shape of the shielding layer according to the treatment plan.

[0033] Furthermore, the intelligent feedback control module specifically includes:

[0034] Biological Dosimetry Monitor:

[0035] (1) Sensor type: non-invasive dose sensors, such as MOSFET or semiconductor detectors, are placed in the target area and surrounding tissue areas;

[0036] (2) Real-time feedback mechanism: The measured dose data is compared with the preset safety threshold. When the threshold is exceeded, an alarm is triggered and the treatment parameters are adjusted;

[0037] Treatment Planning System:

[0038] (1) Integrated software platform: Equipped with cloud-based planning software, such as RayStation or Eclipse, to update the irradiation plan in real time;

[0039] (2) Data integration: Receive imaging data, dose monitoring data, and patient motion data for dynamic optimization.

[0040] Furthermore, the user interaction module specifically includes:

[0041] Physician control terminal:

[0042] (1) Display interface: Provides 3D views and real-time data charts to display target location, dose distribution, and patient status.

[0043] (2) Control function: supports physicians to manually adjust beam intensity, irradiation time or pause treatment.

[0044] Patient status feedback unit:

[0045] (1) Physiological monitoring equipment: including electrocardiogram (ECG), pulse oximeter, and respiratory monitoring belt to capture the patient's status in real time;

[0046] (2) Abnormal feedback: If the patient has abnormal movements or physiological parameters exceed the safe range, the system automatically suspends treatment.

[0047] Another object of the present invention is to provide a radiotherapy protection method for reducing normal tissue damage based on the radiotherapy protection system for reducing normal tissue damage, the method specifically comprising:

[0048] S1: Data initialization, using CT or MRI to obtain the initial images of the patient's target area and normal tissues, and establish a target area model; using AI algorithms to segment the target area and surrounding tissues, and generate an initial dose distribution plan; attaching markers to the patient's body surface and adjusting the infrared tracking device; measuring the patient's breathing pattern and organ displacement range, and establishing a motion correction model; optimizing the radiation dose plan based on biophysical properties, such as density and metabolic activity;

[0049] S2: Real-time imaging and target positioning. Start the high-frame-rate 4D image acquisition device to obtain dynamic images of the target area and surrounding tissues in real time. Use the optical flow algorithm and surface tracking data to perform image correction and locate the target area position and morphology. Input the imaging data into the dose optimization controller and compare it with the initial plan to update the target area position. Use the AI ​​segmentation algorithm to calibrate the target area boundary and predict its possible dynamic position.

[0050] S3: Dynamic dose distribution and shielding: recalculate the irradiation dose distribution through the Monte Carlo algorithm based on real-time image data; adjust the shape of the multi-leaf collimator to make it consistent with the real-time target shape; adjust the thickness and coverage of the electronic shielding layer according to the dynamic position of normal tissue;

[0051] S4: Intelligent feedback control, real-time monitoring of the cumulative dose of the target area and normal tissues to ensure that the dose distribution is within a safe range; if target deviation, abnormal patient movement or dose exceeding the standard is detected, the system automatically pauses treatment and recalibrates;

[0052] S5: Store treatment data, dose distribution, target changes, patient status, etc. on the cloud platform for subsequent evaluation; output treatment reports, including target dose coverage, normal tissue protection and treatment effect evaluation.

[0053] Another object of the present invention is to provide a computer device, which includes a memory and a processor, wherein the memory stores a computer program, and when the computer program is executed by the processor, the processor executes the steps of the radiotherapy protection method for reducing damage to normal tissue.

[0054] Another object of the present invention is to provide a computer-readable storage medium storing a computer program, which, when executed by a processor, enables the processor to perform the steps of the radiotherapy protection method for reducing normal tissue damage.

[0055] Another object of the present invention is to provide an information data processing terminal, which is used to implement the radiotherapy protection system for reducing damage to normal tissues.

[0056] In combination with the above technical solutions and the technical problems solved, the advantages and positive effects of the technical solutions to be protected by the present invention are as follows:

[0057] 1. Real-time and precise irradiation:

[0058] The combination of dynamic imaging and dose optimization technology improves the efficiency of precise irradiation of the target area.

[0059] Effectively deal with target area movement caused by breathing, heartbeat, etc.

[0060] 2. Significantly reduce normal tissue damage:

[0061] The combination of dynamic adjustment of the shielding layer and optimization of dose distribution maximizes the protection of normal tissue.

[0062] Monitor the cumulative dose in real time to avoid excessive exposure.

[0063] 3. Improved intelligence:

[0064] The combination of AI segmentation and dynamic optimization algorithm reduces manual intervention and improves the level of system automation.

[0065] Intelligent feedback mechanism enhances the safety and flexibility of treatment.

[0066] 4. Improve patient experience:

[0067] The system can adjust in real time based on the patient's movement and status to reduce discomfort.

[0068] Reduce treatment complications and improve patients' quality of life.

[0069] 5. Wide applicability:

[0070] It is suitable for radiotherapy scenarios of various types of solid tumors, including lung cancer, liver cancer and prostate cancer.

[0071] Flexible modular design allows for easy integration with existing radiotherapy equipment.

[0072] 6. Dynamic target positioning and real-time protection:

[0073] The system achieves dynamic tracking of the target area through high-frame-rate 4D imaging and AI real-time segmentation algorithm, which significantly reduces irradiation deviation caused by motion compared with traditional static image guidance.

[0074] The linkage design of the electronic shielding layer and the dose distribution module significantly reduces the cumulative radiation dose of normal tissues.

[0075] 7. High-precision dose optimization:

[0076] The dynamic dose distribution algorithm combined with the multi-leaf collimator enables the radiation beam to adapt to the shape of the target area, avoiding irradiation of non-target areas and improving treatment safety.

[0077] The biological dose monitor provides real-time feedback of the cumulative dose of the target and non-target areas, optimizes the irradiation path, and avoids excessive radiation.

[0078] 8.Intelligence and Automation:

[0079] The introduction of AI algorithms reduces the complexity of manual calibration by physicians in traditional systems, speeds up the treatment process and improves treatment efficiency.

[0080] The intelligent feedback module adjusts the treatment plan in real time, enhancing the system's resilience and ensuring patient safety.

[0081] 9. Improve patient experience:

[0082] Dynamic shielding and optimized beam control reduce patient side effects during treatment.

[0083] The system can be linked with the patient's physiological monitoring data to automatically adjust parameters according to the patient's condition to improve treatment comfort.

[0084] 10. Clinical effects and application prospects:

[0085] Significantly reduce the probability of radiation damage to normal tissues and reduce complications caused by radiotherapy, such as tissue fibrosis and functional disorders.

[0086] Improve the dose coverage and treatment effect of the tumor target area and increase the success rate of treatment.

[0087] The present invention breaks through the limitations of traditional radiotherapy technology in terms of real-time performance and protective effect through dynamic real-time monitoring, dose distribution optimization and intelligent feedback control. The system significantly reduces the damage to normal tissues, improves treatment accuracy and patient experience, and has a wide range of clinical application value. BRIEF DESCRIPTION OF THE DRAWINGS

[0088] Figure 1 is a structural diagram of a radiotherapy protection system for reducing normal tissue damage provided by an embodiment of the present invention;

[0089] Figure 2 is a structural diagram of a real-time imaging and monitoring module provided by an embodiment of the present invention;

[0090] Figure 3 is a structural diagram of a dynamic protection dosage distribution module provided by an embodiment of the present invention;

[0091] Figure 4 is a flow chart of a radiotherapy protection method for reducing normal tissue damage provided by an embodiment of the present invention;

[0092] In the figure: 1. Real-time imaging and monitoring module; 2. Dynamic protection dose distribution module; 3. Intelligent feedback control module; 4. User interaction module; 5. High frame rate 4D image acquisition equipment; 6. Tissue segmentation and tracking unit; 7. Motion capture system; 8. Dose optimization controller; 9. Multi-leaf collimator MLC; 10. Electronic shielding layer device. DETAILED DESCRIPTION

[0093] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0094] like Figure 1 As shown, an embodiment of the present invention provides a radiation therapy protection system for reducing normal tissue damage, the system comprising:

[0095] Real-time imaging and monitoring module 1 uses high-speed CT or MRI equipment to obtain 4D images of the patient's target area and surrounding tissues in real time during treatment; uses artificial intelligence (AI) algorithms to automatically segment imaging data and identify the target area and adjacent normal tissues in real time; uses infrared trackers or electronic surface trackers to capture the patient's body surface movement and internal organ displacement in real time;

[0096] The dynamic protection dose distribution module 2 is connected to the real-time imaging and monitoring module 1. It dynamically calculates the dose distribution of each radiation according to the real-time imaging data, optimizes the irradiation path, and reduces the dose to normal tissues. It is equipped with a high-precision collimation system to adjust the shape and intensity of the radiation beam to adapt to the dynamic changes of the target area. It is equipped with a shielding layer with adjustable thickness and shape to protect normal tissues in non-target areas.

[0097] The intelligent feedback control module 3 is connected to the real-time imaging and monitoring module 1 to detect the cumulative dose of the target area and normal tissues in real time and dynamically adjust the irradiation strategy; the real-time imaging and dose monitoring data are input into the treatment planning system to update the irradiation plan;

[0098] The user interaction module 4 is connected to the real-time imaging and monitoring module 1 to provide a real-time display interface for radiotherapy, support physicians to intervene in real-time to adjust treatment parameters; monitor the patient's physiological data, such as breathing and heartbeat, in real time, and feed it back to the system.

[0099] Detailed working principle:

[0100] 1. Real-time imaging and monitoring:

[0101] The core of the system is the real-time imaging and monitoring module, which uses high-speed CT or MRI equipment to obtain 4D images of the patient's target area and surrounding tissues in real time during treatment. Through artificial intelligence (AI) algorithms, the system can automatically segment these imaging data, identify the target area and adjacent normal tissues in real time, and accurately mark them. At the same time, infrared trackers or electronic surface trackers are used to capture the movement of the patient's body surface and the displacement of internal organs in real time to ensure the accuracy and real-time nature of the imaging data, thereby providing support for precise control during subsequent treatment.

[0102] 2. Dynamic protection dose distribution:

[0103] During the treatment process, the dynamic protection dose distribution module will continuously adjust the radiation dose distribution according to the real-time imaging data. Through intelligent calculation, the system will dynamically calculate the irradiation path and optimize the dose distribution during each radiotherapy to minimize the radiation dose of normal tissue. During this process, the high-precision collimation system can accurately adjust the shape and intensity of the radiation beam to adapt to the dynamic changes of the target area and ensure that the radiation energy is concentrated in the target area. At the same time, the system is equipped with a shielding layer with adjustable thickness and shape to further protect normal tissues in non-target areas from excessive radiation.

[0104] 3. Intelligent feedback control:

[0105] To ensure the effectiveness and safety of treatment, the intelligent feedback control module monitors the cumulative dose of the target area and surrounding normal tissues in real time. When it is found that the radiation dose of normal tissues is close to or exceeds the safe value, the system can dynamically adjust the irradiation strategy and intervene in time by modifying the irradiation path or dose distribution. In addition, the treatment planning system will update the irradiation plan in real time, using the latest imaging and dose data as input to ensure the accuracy and individualization of each treatment.

[0106] 4. User interaction and real-time intervention:

[0107] The user interaction module provides a real-time display interface for radiotherapy, allowing doctors to observe and adjust treatment parameters in real time. By connecting to the real-time imaging and monitoring module, doctors can monitor the patient's physiological data, such as breathing and heartbeat, in real time and provide timely feedback to the system. This module supports doctors to intervene and adjust the treatment process, ensuring flexibility and safety during the treatment process, thereby optimizing and adjusting the patient's individualized treatment plan.

[0108] like Figure 2 As shown, the real-time imaging and monitoring module 1 specifically includes:

[0109] High frame rate 4D image acquisition equipment 5:

[0110] (1) Imaging equipment selection: Use 64-row or higher high-speed CT or superconducting 3T MRI to ensure clear capture of the target area and surrounding tissues during treatment, with an acquisition frame rate of 10-20 frames per second;

[0111] (2) Image preprocessing unit: De-noise and enhance the image during the acquisition process to reduce blur caused by patient movement and improve segmentation accuracy.

[0112] Tissue Segmentation and Tracking Unit 6:

[0113] (1) AI model library: pre-loaded deep learning models, such as U-Net and ResNet, for automatic segmentation of target areas, such as tumor tissue, and normal tissues, such as nerves and blood vessels.

[0114] (2) Real-time tracking algorithm: Based on the combination of optical flow method and Kalman filter, it can capture the displacement changes of target area and normal tissue under dynamic conditions such as breathing movement and heartbeat;

[0115] Motion Capture System7:

[0116] (1) Surface tracking device: Attach markers such as reflective balls or fluorescent markers to the patient's body surface and track the patient's body surface movement through an infrared camera;

[0117] (2) Internal motion compensation: Use a respiratory sensor belt and abdominal pressure sensor to capture the displacement of internal organs and perform real-time correction of image data.

[0118] The dynamic protection dosage distribution module 2 specifically includes:

[0119] Dose Optimization Controller 8:

[0120] (1) Core algorithm: Based on the Monte Carlo algorithm and dose volume histogram (DVH), the irradiation dose distribution is calculated in real time;

[0121] (2) Dynamic dose adjustment: The intensity and distribution of radiation dose are adjusted according to real-time images to ensure that sufficient dose is provided to the target area while avoiding over-irradiation of normal tissues;

[0122] Multi-leaf collimator MLC9:

[0123] (1) Blade control accuracy: Using servo motor control, the accuracy reaches 0.5 mm, achieving precise matching of the target area shape;

[0124] (2) Dynamic reconstruction function: The beam shape can be adjusted according to the real-time deformation of the target area and linked with the dose optimization controller;

[0125] Electronic shielding layer device 10:

[0126] (1) Material selection: Use high atomic number materials with variable thickness, such as tungsten alloys, combined with flexible polymer layers to achieve shielding;

[0127] (2) Shape adjustment: Equipped with a micro electric drive to automatically adjust the shape of the shielding layer according to the treatment plan.

[0128] The intelligent feedback control module specifically includes:

[0129] Biological Dosimetry Monitor:

[0130] (1) Sensor type: non-invasive dose sensors, such as MOSFET or semiconductor detectors, are placed in the target area and surrounding tissue areas;

[0131] (2) Real-time feedback mechanism: The measured dose data is compared with the preset safety threshold. When the threshold is exceeded, an alarm is triggered and the treatment parameters are adjusted;

[0132] Treatment Planning System:

[0133] (1) Integrated software platform: Equipped with cloud-based planning software, such as RayStation or Eclipse, to update the irradiation plan in real time;

[0134] (2) Data integration: Receive imaging data, dose monitoring data, and patient motion data for dynamic optimization.

[0135] The user interaction module specifically includes:

[0136] Physician control terminal:

[0137] (1) Display interface: Provides 3D views and real-time data charts to display target location, dose distribution, and patient status.

[0138] (2) Control function: supports physicians to manually adjust beam intensity, irradiation time or pause treatment.

[0139] Patient status feedback unit:

[0140] (1) Physiological monitoring equipment: including electrocardiogram (ECG), pulse oximeter, and respiratory monitoring belt to capture the patient's status in real time;

[0141] (2) Abnormal feedback: If the patient has abnormal movements or physiological parameters exceed the safe range, the system automatically suspends treatment.

[0142] like Figure 4 As shown, an embodiment of the present invention provides a radiotherapy protection method for reducing normal tissue damage based on the radiotherapy protection system for reducing normal tissue damage, and the method specifically includes:

[0143] S1: Data initialization, using CT or MRI to obtain the initial images of the patient's target area and normal tissues, and establish a target area model; using AI algorithms to segment the target area and surrounding tissues, and generate an initial dose distribution plan; attaching markers to the patient's body surface and adjusting the infrared tracking device; measuring the patient's breathing pattern and organ displacement range, and establishing a motion correction model; optimizing the radiation dose plan based on biophysical properties, such as density and metabolic activity;

[0144] S2: Real-time imaging and target positioning. Start the high-frame-rate 4D image acquisition device to obtain dynamic images of the target area and surrounding tissues in real time. Use the optical flow algorithm and surface tracking data to perform image correction and locate the target area position and morphology. Input the imaging data into the dose optimization controller and compare it with the initial plan to update the target area position. Use the AI ​​segmentation algorithm to calibrate the target area boundary and predict its possible dynamic position.

[0145] S3: Dynamic dose distribution and shielding: recalculate the irradiation dose distribution through the Monte Carlo algorithm based on real-time image data; adjust the shape of the multi-leaf collimator to make it consistent with the real-time target shape; adjust the thickness and coverage of the electronic shielding layer according to the dynamic position of normal tissue;

[0146] S4: Intelligent feedback control, real-time monitoring of the cumulative dose of the target area and normal tissues to ensure that the dose distribution is within a safe range; if target deviation, abnormal patient movement or dose exceeding the standard is detected, the system automatically pauses treatment and recalibrates;

[0147] S5: Store treatment data, dose distribution, target changes, patient status, etc. on the cloud platform for subsequent evaluation; output treatment reports, including target dose coverage, normal tissue protection and treatment effect evaluation.

[0148] An embodiment of the present invention provides a computer device, which includes a memory and a processor. The memory stores a computer program. When the computer program is executed by the processor, the processor executes the steps of the radiotherapy protection method for reducing normal tissue damage.

[0149] An embodiment of the present invention provides a computer-readable storage medium storing a computer program. When the computer program is executed by a processor, the processor executes the steps of the radiotherapy protection method for reducing normal tissue damage.

[0150] An embodiment of the present invention provides an information data processing terminal, which is used to implement the radiotherapy protection system for reducing normal tissue damage.

[0151] 1. Specific application fields or related products of the present invention:

[0152] The present invention relates to the field of radiotherapy technology, and is specifically applied to technologies for improving the precise radiation of target areas and protecting normal tissues during radiotherapy. The invention is particularly applicable to radiotherapy systems in tumor treatment, and in tumor target area treatment, the coordinated work of real-time imaging and monitoring systems, dynamic protective dose distribution, intelligent feedback control, and real-time user intervention modules can minimize the damage to normal tissues and improve the accuracy and effect of treatment.

[0153] This technology can be applied to tumor radiotherapy systems, cancer treatment equipment, CT or MRI auxiliary treatment equipment and related medical equipment, especially for complex tumor treatment processes, including the treatment of various types of tumor patients such as lung cancer, breast cancer, brain cancer, prostate cancer, etc. In addition, this technology can also be extended to other medical fields that require precise radiation control and dynamic monitoring, such as real-time physiological monitoring and intervention of patients during radiotherapy to ensure safety and effectiveness.

[0154] II. Evidence related to the technical effects obtained by the embodiments of the present invention:

[0155] 1. Effects of real-time imaging and monitoring modules:

[0156] In an embodiment of the present invention, the 4D images acquired by high-speed CT or MRI equipment are combined with real-time data segmentation of artificial intelligence (AI) algorithms to accurately identify the boundary between the target area and normal tissue, providing strong data support for the accuracy of radiotherapy. In clinical applications, real-time image segmentation and target recognition make the positioning of the target area more accurate and effectively avoid radiation damage to normal tissue. Real-time motion capture by infrared trackers and electronic surface trackers ensures that the target area can be accurately irradiated during radiotherapy even when the patient moves.

[0157] 2. Effect of dynamic protection dose distribution module:

[0158] By dynamically calculating the dose distribution and irradiation path of each radiation, the module can automatically adjust the irradiation angle and radiation intensity to prevent the radiation beam from over-irradiating the surrounding healthy tissue. For example, in the actual treatment process, through the cooperation of the high-precision collimation system, it can ensure that the radiation dose is concentrated in the tumor area and reduce the exposure of normal tissue. The introduction of this technology effectively reduces the side effects of treatment, especially when used in high-risk areas (such as the lungs and brain), which can significantly improve the safety of patient treatment.

[0159] 3. Effect of intelligent feedback control module:

[0160] During radiotherapy, the dose of the target area and normal tissue is monitored in real time, and the intelligent feedback control module can detect and correct treatment deviations in a timely manner. Through dynamic adjustment based on real-time data, over-irradiation or insufficient dose is avoided. This technology ensures the accurate distribution of treatment doses, prevents excessive radiation from damaging healthy tissues, and improves the treatment effect. For example, during radiotherapy for some patients, as the treatment progresses, the morphology of the target area may change slightly. Intelligent feedback control can respond quickly, adjust the treatment plan and radiation path, and ensure maximum treatment effect.

[0161] 4. Effects of user interaction and real-time intervention modules:

[0162] The user interaction module in the present invention provides a real-time display interface for radiotherapy, allowing doctors to intervene and adjust treatment parameters at any time. In particular, when abnormalities occur, doctors can quickly make judgments and adjust treatment strategies through the system. The system's real-time monitoring of the patient's physiological data (such as breathing and heartbeat) can help doctors better understand the patient's physiological state, thereby adjusting treatment strategies and reducing risks during treatment. Clinical verification results show that this module can effectively improve the personalization and flexibility of treatment and reduce risks and uncertainties during treatment.

[0163] Combined with the technical effects of the above embodiments, the present invention realizes high-precision, high-safety and high-efficiency radiotherapy in radiotherapy, effectively reduces normal tissue damage during treatment, and improves the accuracy of tumor treatment, providing feasibility evidence and significant technological progress for clinical treatment.

[0164] It should be noted that the embodiments of the present invention can be implemented by hardware, software, or a combination of software and hardware. The hardware part can be implemented using dedicated logic; the software part can be stored in a memory and executed by an appropriate instruction execution system, such as a microprocessor or dedicated design hardware. It can be understood by a person of ordinary skill in the art that the above-mentioned devices and methods can be implemented using computer executable instructions and / or contained in a processor control code, such as a carrier medium such as a disk, CD or DVD-ROM, a programmable memory such as a read-only memory (firmware), or a data carrier such as an optical or electronic signal carrier. Such code is provided on the carrier medium. The device and its modules of the present invention can be implemented by hardware circuits such as very large-scale integrated circuits or gate arrays, semiconductors such as logic chips, transistors, etc., or programmable hardware devices such as field programmable gate arrays, programmable logic devices, etc., can also be implemented by software executed by various types of processors, and can also be implemented by a combination of the above-mentioned hardware circuits and software, such as firmware.

[0165] The above description is only a specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Any modifications, equivalent substitutions and improvements made by any technician familiar with the technical field within the technical scope disclosed by the present invention and within the spirit and principle of the present invention should be covered by the protection scope of the present invention.

Claims

1. A radiation therapy protection system for reducing normal tissue damage, characterized in that: The system includes: Real-time imaging and monitoring module, using high-speed CT or MRI equipment to obtain 4D images of the patient's target area and surrounding tissues in real time during treatment; automatic segmentation of imaging data through artificial intelligence (AI) algorithms to identify the target area and adjacent normal tissues in real time; and use infrared trackers or electronic surface trackers to capture the patient's body surface movement and internal organ displacement in real time; The dynamic protection dose distribution module is connected to the real-time imaging and monitoring module. Based on the real-time imaging data, it dynamically calculates the dose distribution of each radiation, optimizes the irradiation path, and reduces the dose to normal tissues. It is equipped with a high-precision collimation system to adjust the shape and intensity of the radiation beam to adapt to the dynamic changes of the target area. It is equipped with a shielding layer with adjustable thickness and shape to protect normal tissues in non-target areas. The intelligent feedback control module is connected to the real-time imaging and monitoring module to detect the cumulative dose of the target area and normal tissues in real time and dynamically adjust the irradiation strategy; the real-time imaging and dose monitoring data are input into the treatment planning system to update the irradiation plan; The user interaction module is connected to the real-time imaging and monitoring module to provide a real-time display interface for radiotherapy, supporting physicians to intervene in real time to adjust treatment parameters; it monitors the patient's physiological data, such as breathing and heartbeat, in real time and feeds it back to the system.

2. The radiation therapy protection system for reducing normal tissue damage according to claim 1, characterized in that: The real-time imaging and monitoring module specifically includes: High frame rate 4D image acquisition equipment: (1) Imaging equipment selection: Use 64-row or higher high-speed CT or superconducting 3T MRI to ensure clear capture of the target area and surrounding tissues during treatment, with an acquisition frame rate of 10-20 frames per second; (2) Image preprocessing unit: De-noise and enhance the image during the acquisition process to reduce blur caused by patient movement and improve segmentation accuracy. Tissue segmentation and tracking unit: (1) AI model library: pre-loaded deep learning models, such as U-Net and ResNet, for automatic segmentation of target areas, such as tumor tissue, and normal tissues, such as nerves and blood vessels. (2) Real-time tracking algorithm: Based on the combination of optical flow method and Kalman filter, it can capture the displacement changes of target area and normal tissue under dynamic conditions such as breathing movement and heartbeat; Motion Capture System: (1) Surface tracking device: Attach markers such as reflective balls or fluorescent markers to the patient's body surface and track the patient's body surface movement through an infrared camera; (2) Internal motion compensation: Use a respiratory sensor belt and abdominal pressure sensor to capture the displacement of internal organs and perform real-time correction of image data.

3. The radiation therapy protection system for reducing normal tissue damage according to claim 1, characterized in that: The dynamic protection dosage distribution module specifically includes: Dose Optimization Controller: (1) Core algorithm: Based on the Monte Carlo algorithm and dose volume histogram (DVH), the irradiation dose distribution is calculated in real time; (2) Dynamic dose adjustment: The intensity and distribution of radiation dose are adjusted according to real-time images to ensure that sufficient dose is provided to the target area while avoiding over-irradiation of normal tissues; Multi-leaf collimator MLC: (1) Blade control accuracy: Using servo motor control, the accuracy reaches 0.5 mm, achieving precise matching of the target area shape; (2) Dynamic reconstruction function: The beam shape can be adjusted according to the real-time deformation of the target area and linked with the dose optimization controller; Electronic shielding device: (1) Material selection: Use high atomic number materials with variable thickness, such as tungsten alloys, combined with flexible polymer layers to achieve shielding; (2) Shape adjustment: Equipped with a micro electric drive to automatically adjust the shape of the shielding layer according to the treatment plan.

4. The radiation therapy protection system for reducing normal tissue damage according to claim 1, characterized in that: The intelligent feedback control module specifically includes: Biological Dosimetry Monitor: (1) Sensor type: non-invasive dose sensors, such as MOSFET or semiconductor detectors, are placed in the target area and surrounding tissue areas; (2) Real-time feedback mechanism: The measured dose data is compared with the preset safety threshold. When the threshold is exceeded, an alarm is triggered and the treatment parameters are adjusted; Treatment Planning System: (1) Integrated software platform: Equipped with cloud-based planning software, such as RayStation or Eclipse, to update the irradiation plan in real time; (2) Data integration: Receive imaging data, dose monitoring data, and patient motion data for dynamic optimization.

5. The radiation therapy protection system for reducing normal tissue damage according to claim 1, characterized in that: The user interaction module specifically includes: Physician control terminal: (1) Display interface: Provides 3D views and real-time data charts to display target location, dose distribution, and patient status. (2) Control function: supports physicians to manually adjust beam intensity, irradiation time or pause treatment. Patient status feedback unit: (1) Physiological monitoring equipment: including electrocardiogram (ECG), pulse oximeter, and respiratory monitoring belt to capture the patient's status in real time; (2) Abnormal feedback: If the patient has abnormal movements or physiological parameters exceed the safe range, the system automatically suspends treatment.

6. A method for protecting normal tissue from radiation therapy based on the radiation therapy protection system for reducing normal tissue damage as described in claims 1 to 5, characterized in that: The method specifically includes: S1: Data initialization, using CT or MRI to obtain the initial images of the patient's target area and normal tissues, and establish a target area model; using AI algorithms to segment the target area and surrounding tissues, and generate an initial dose distribution plan; attaching markers to the patient's body surface and adjusting the infrared tracking device; measuring the patient's breathing pattern and organ displacement range, and establishing a motion correction model; optimizing the radiation dose plan based on biophysical properties, such as density and metabolic activity; S2: Real-time imaging and target positioning. Start the high-frame-rate 4D image acquisition device to obtain dynamic images of the target area and surrounding tissues in real time. Use the optical flow algorithm and surface tracking data to perform image correction and locate the target area position and morphology. Input the imaging data into the dose optimization controller and compare it with the initial plan to update the target area position. Use the AI ​​segmentation algorithm to calibrate the target area boundary and predict its possible dynamic position. S3: Dynamic dose distribution and shielding: recalculate the irradiation dose distribution through the Monte Carlo algorithm based on real-time image data; adjust the shape of the multi-leaf collimator to make it consistent with the real-time target shape; adjust the thickness and coverage of the electronic shielding layer according to the dynamic position of normal tissue; S4: Intelligent feedback control, real-time monitoring of the cumulative dose of the target area and normal tissues to ensure that the dose distribution is within a safe range; if target deviation, abnormal patient movement or dose exceeding the standard is detected, the system automatically pauses treatment and recalibrates; S5: Store treatment data, dose distribution, target changes, patient status, etc. on the cloud platform for subsequent evaluation; output treatment reports, including target dose coverage, normal tissue protection and treatment effect evaluation.

7. A computer device, characterized in that: The computer device includes a memory and a processor, wherein the memory stores a computer program, and when the computer program is executed by the processor, the processor executes the steps of the radiotherapy protection method for reducing normal tissue damage as claimed in claim 6.

8. A computer-readable storage medium storing a computer program, wherein when the computer program is executed by a processor, the processor executes the steps of the radiotherapy protection method for reducing normal tissue damage as claimed in claim 6.

9. An information data processing terminal, characterized in that: The information data processing terminal is used to implement the radiotherapy protection system for reducing normal tissue damage as described in any one of claims 1-5.

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