Traditional Chinese medicine formula for preventing African swine fever, preparation method and feed composition

Abstract

The invention provides a traditional Chinese medicine formula for preventing African swine fever, a preparation method and a feed composition. The traditional Chinese medicine formula is prepared from the following raw materials in parts by mass: 10 to 20 parts of radix rehmanniae, 6 to 12 parts of radix arnebiae seu lithospermi, 9 to 21 parts of cortex phellodendri, 10 to 19 parts of folium isatidis, 8 to 14 parts of fructus gardeniae, 6 to 12 parts of herba scutellariae barbatae, 6 to 12 parts of herba lobeliae chinensis, 7 to 18 parts of herba hedyotis diffusae, 8 to 18 parts of radix platycodonis, 6 to 12 parts of flos lonicerae and 3 to 10 parts of radix glycyrrhizae. The traditional Chinese medicine formula has a good prevention effect on African swine fever.

Description

Technical Field

[0001] The present invention belongs to the field of prevention and treatment of classical swine fever, and particularly relates to a traditional Chinese medicine formula for preventing African swine fever, a preparation method thereof, and a feed composition. Background Art

[0002] African swine fever is an acute, hemorrhagic, highly contagious disease caused by the African swine fever virus. The remarkable feature of this disease is the rapid progression of the disease course, and the mortality rate of the most acute and acute cases is almost 100%. The main clinical symptoms include high fever (body temperature can rise to 40 - 42 °C), increased heart rate, dyspnea, and cough in some cases. Diseased pigs may also secrete serous or mucopurulent substances from the eyes and nose, and the skin shows cyanosis. In addition, obvious bleeding symptoms will appear in the lymph nodes, kidneys, gastrointestinal mucosa and other parts. The clinical manifestations of African swine fever have many similarities with classical swine fever; while the infection with attenuated strains is mainly manifested as respiratory symptoms and occasional cases. This disease mainly affects sows and fattening pigs, and has a relatively low infectivity to piglets. Diseased pigs and latent virus-carrying pigs are the main sources of transmission of this disease. Infected sows will significantly excrete the virus, and the virus can be excreted through nasal secretions, feces, urine and other channels. Even pigs that have withstood the virus may carry the virus for a long time and excrete the virus to the outside world irregularly. Therefore, the prevention and control of African swine fever is particularly important, and strict biosafety measures need to be taken to contain the spread of the virus.

[0003] China is a large country in pig breeding and pork consumption. The annual output, inventory of live pigs and pork consumption volume are all ranked first in the world. The total annual import volume of breeding pigs and pork products is huge. There is frequent trade with many countries, and the number of goods carried by passengers is large and the types are miscellaneous. Therefore, the risk of African swine fever being introduced into China is increasing day by day. Once introduced, the direct and indirect losses will be immeasurable. Therefore, how to effectively prevent African swine fever is the key problem that the current pig breeding industry urgently needs to solve.

[0004] In view of this, the present invention is specifically proposed. Summary of the Invention The first object of the present invention is to provide a traditional Chinese medicine formula for preventing African swine fever. Through scientific raw materials and proportion configuration, this traditional Chinese medicine formula can achieve the effects of clearing heat and detoxifying, clearing heat and cooling blood, strengthening the healthy qi and eliminating pathogenic factors, and dissipating stasis and resolving masses. When used in daily feeding, it can effectively prevent the occurrence of African swine fever.

[0006] The second object of the present invention is to provide a preparation method of the above traditional Chinese medicine formula. This method is simple to operate, has a low cost, and has the characteristics of high efficiency, environmental protection and economy. The prepared traditional Chinese medicine formula can effectively prevent the occurrence of African swine fever.

[0007] The third object of the present invention is to provide a feed composition, wherein the above-mentioned Chinese medicine formula is added to the feed composition. The feed composition is used to feed pigs, which can effectively prevent the occurrence of African swine fever.

[0008] In order to achieve the above-mentioned purpose of the present invention, the following technical solutions are particularly adopted: The present invention provides a traditional Chinese medicine formula for preventing African swine fever, which comprises the following raw materials in parts by mass: 10-20 parts of raw rehmannia, 6-12 parts of lithospermum officinale, 9-21 parts of phellodendron, 10-19 parts of isatis indigotica, 8-14 parts of gardenia, 6-12 parts of scutellaria barbata, 6-12 parts of lobelia, 7-18 parts of shepherd's purse, 8-18 parts of platycodon grandiflorum, 6-12 parts of honeysuckle, and 3-10 parts of liquorice.

[0009] The above technical scheme of the present invention can achieve the effects of clearing away heat and detoxifying, clearing heat and cooling blood, strengthening the body and eliminating evil, eliminating carbuncle and dispersing knots by organically combining various components, so as to prevent African swine fever. Specifically, in this component, the raw earth has the effects of nourishing yin and clearing heat, cooling blood and detoxifying, and can be used for clearing heat and detoxifying, and fighting against fever symptoms caused by viruses. Lithospermum officinale has the effects of clearing heat and cooling blood, detoxifying and clearing rashes. Phellodendron chinense has the effects of clearing heat and drying dampness, purging fire and detoxifying. Folium isatidis has the effects of clearing heat and detoxifying, cooling blood and eliminating spots. Gardenia has the effects of clearing heat and purging fire, cooling blood and detoxifying. Scutellaria barbata and Scutellaria baicalensis both have the effects of clearing heat and detoxifying, promoting diuresis and reducing swelling. White flower snake grass has the effects of clearing heat and detoxifying, promoting dampness and relieving stranguria. Platycodon grandiflorum has the effects of ventilating the lungs, removing phlegm and discharging pus. Honeysuckle has the effects of clearing heat and detoxifying, cooling blood and dispersing wind. Licorice has the effects of reconciling various medicines and alleviating drug toxicity. According to the TCM theory of monarch, minister, assistant and envoy, this Chinese medicine formula uses raw rehmannia as the monarch medicine, clearing away heat and detoxifying, cooling blood and reducing fever; lithospermum officinale and phellodendron are ministerial medicines, which assist in enhancing the power of clearing heat and cooling blood and detoxifying; isatis indigo leaf and gardenia are adjuvants, clearing heat and purging fire, cooling blood and detoxifying, and improving blood circulation at the same time; barbata, lobelia, white flower snake grass, platycodon grandiflorum, honeysuckle are envoys, harmonize the various medicines, guide the power of the medicine, enhance the effect of clearing heat and detoxifying, and help relieve respiratory symptoms; licorice harmonizes the various medicines and reduces side effects. In addition, in this Chinese medicine formula, raw rehmannia, phellodendron grandiflorum and gardenia jointly play the role of clearing heat and detoxifying, cooling blood, and can fight against fever and bleeding symptoms caused by viruses. Lithospermum officinale and isatis indigo leaf jointly enhance the effect of clearing heat and cooling blood and detoxifying. Barbata and lobelia work together to improve blood circulation and enhance the body's resistance. White flower snake grass and honeysuckle jointly enhance the power of clearing heat and detoxifying to fight viruses. Platycodon grandiflorum and licorice can jointly relieve respiratory symptoms and harmonize the medicinal properties. In short, this Chinese medicine formula can play a better role in preventing African swine fever by following the Chinese medicine theory of monarch, minister, assistant and envoy, and applying the synergistic effect among various components.

[0010] Preferably, by mass parts, it further includes: 7-14 parts of gypsum. In this embodiment, by adding gypsum, its effects of clearing heat and purging fire, and relieving restlessness and thirst can be exerted to relieve the symptoms of high fever and restlessness and thirst in diseased pigs. The gypsum in this embodiment serves as the monarch drug in the whole formula. It can be combined with rehmannia root to enhance the heat-clearing effect. At the same time, gypsum is cold in nature and rehmannia root is cool in nature. The combination of the two can be mutually reconciled, reducing the side effects of a single medicinal material, making the medicinal property more mild, nourishing yin without harming the healthy qi, and avoiding damaging pigs while preventing African swine fever. By limiting its addition amount, when combined with rehmannia root, rehmannia root can better nourish yin, thus complementing the heat-clearing effect of gypsum to achieve a state of yin-yang balance. And it can relieve the cold nature of gypsum, reduce the side effects on the spleen and stomach, and make the whole prescription more gentle. In addition, this ratio can improve the effect of nourishing yin and clearing heat of the whole prescription, making the heat-clearing effect of gypsum more effective, thereby improving the overall curative effect.

[0011] Preferably, by mass parts, it further includes: 6-12 parts of chuanxiong rhizome. Chuanxiong rhizome has the effects of promoting blood circulation and qi movement, dispelling wind and relieving pain, and can be used to improve blood circulation. Combining chuanxiong rhizome with platycodon root and restricting the addition amounts of both can enhance the lung-dispersing effect of platycodon root and help the medicinal effect of chuanxiong rhizome to be exerted better. According to the theory of monarch, minister, assistant, and guide, chuanxiong rhizome can be used as the minister drug, assisting the monarch drug together with gardenia fruit to enhance the effects of clearing heat and detoxifying and promoting blood circulation and removing stasis of the whole traditional Chinese medicine formula. In addition, by restricting the addition amounts of chuanxiong rhizome, scutellaria barbata, and lobelia chinensis, the cold and heat properties of the medicinal materials can be balanced, avoiding damaging the constitution of pigs during the prevention of swine fever. And this ratio can work together in aspects such as antiviral, improving immunity, and improving blood circulation, which helps to further prevent African swine fever.

[0012] Preferably, by mass parts, it includes the following raw materials: 11-16 parts of rehmannia root, 8-11 parts of lithospermum root, 10-18 parts of phellodendron bark, 12-18 parts of folium isatidis, 8-11 parts of gypsum, 9-13 parts of gardenia fruit, 7-10 parts of chuanxiong rhizome, 7-10 parts of scutellaria barbata, 7-10 parts of lobelia chinensis, 9-15 parts of oldenlandia diffusa, 9-11 parts of platycodon root, 7-11 parts of honeysuckle flower, 5-9 parts of licorice root.

[0013] Preferably, by mass parts, it includes the following raw materials: 12 parts of rehmannia root, 10 parts of lithospermum root, 12 parts of phellodendron bark, 15 parts of folium isatidis, 9 parts of gypsum, 10 parts of gardenia fruit, 8 parts of chuanxiong rhizome, 8 parts of scutellaria barbata, 8 parts of lobelia chinensis, 12 parts of oldenlandia diffusa, 12 parts of platycodon root, 10 parts of honeysuckle flower, 8 parts of licorice root.

[0014] The present invention also provides a preparation method of a traditional Chinese medicine formula for preventing African swine fever. This method is used to prepare the traditional Chinese medicine formula of any one of the above embodiments, and the method includes: Mix all the raw materials and stir evenly. Crush the mixed raw materials to obtain the traditional Chinese medicine formula.

[0015] The preparation method of this solution is simple. Only mixing and crushing are required to obtain the traditional Chinese medicine formula. This preparation method is efficient, environmentally friendly and economical, and the prepared traditional Chinese medicine formula can effectively prevent the occurrence of African swine fever.

[0016] Preferably, the crushing of the mixed raw materials includes: Primarily crush the mixed raw materials. Filter the primarily crushed raw materials using a 60-mesh sieve. Crush the raw materials obtained after filtration using an ultrafine grinder.

[0017] Through two-stage crushing and filtration, the medicinal materials can be crushed into finer particles, ensuring better mixing of various medicinal material components during mixing. At the same time, the ultrafine grinder can crush the medicinal materials to a finer degree, even reaching the level of cell wall breaking, which can greatly improve the release and bioavailability of the active ingredients in the medicinal materials. In addition, the fine medicinal material particles contribute to the interaction between various components, possibly enhancing the synergistic effect between the medicinal materials and improving the overall therapeutic effect.

[0018] The present invention also provides a feed composition for preventing African swine fever, including: feed and the traditional Chinese medicine formula of any one of the above embodiments, wherein the traditional Chinese medicine formula accounts for 0.2% - 0.5% of the feed composition. By adding the traditional Chinese medicine formula in the above feed mixture in a certain proportion, the effect of preventing African swine fever can be achieved, and using traditional Chinese medicine as a feed additive can reduce the dependence on antibiotics and lower the risk of drug residues. In this embodiment, the traditional Chinese medicine formula accounts for 0.2% - 0.5% of the feed composition. This addition amount can ensure the efficacy of the traditional Chinese medicine components without overly diluting other nutritional components in the feed, and reduces the risk of adverse reactions caused by excessive addition. In addition, appropriate addition can balance cost and effect and avoid waste of resources.

[0019] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) By organically combining various components, the effects of clearing heat and detoxifying, clearing heat and cooling blood, strengthening the healthy qi and eliminating pathogenic factors, and dissipating stasis and resolving masses can be achieved, thereby playing a role in preventing African swine fever. (2) In this traditional Chinese medicine formula, Rehmannia glutinosa is used as the monarch drug to clear heat and detoxify, cool the blood and reduce fever; Arnebia euchroma and Phellodendron amurense are used as the minister drugs to assist in enhancing the power of clearing heat and cooling the blood, and detoxifying; Isatis indigotica and Gardenia jasminoides are used as the assistant drugs to clear heat and purge fire, cool the blood and detoxify, and at the same time improve blood circulation; Scutellaria barbata, Lobelia chinensis, Hedyotis diffusa, Platycodon grandiflorum, and Lonicera japonica are used as the envoy drugs to harmonize the various drugs, guide the medicinal power, enhance the effect of clearing heat and detoxifying, and help relieve respiratory symptoms; Licorice is used to harmonize the various drugs and reduce side effects. (3) In this traditional Chinese medicine formula, Rehmannia glutinosa, Phellodendron amurense, and Gardenia jasminoides work together to clear heat and detoxify, cool the blood, and can counteract the fever and bleeding symptoms caused by the virus. Arnebia euchroma and Isatis indigotica work together to enhance the effect of clearing heat and cooling the blood, and detoxifying. Scutellaria barbata and Lobelia chinensis cooperate to improve blood circulation and enhance the body's resistance. Hedyotis diffusa and Lonicera japonica work together to enhance the power of clearing heat and detoxifying and counteract the virus. Platycodon grandiflorum and Licorice can jointly relieve respiratory symptoms and harmonize the properties of the medicine. (4) By following the theory of monarch, minister, assistant, and envoy in traditional Chinese medicine and applying the synergistic effect among the various components, this traditional Chinese medicine formula can play a better role in preventing African swine fever. Detailed implementation manners The technical solutions of the present invention will be clearly and completely described below in conjunction with the detailed implementation manners. However, those skilled in the art will understand that the following described embodiments are some embodiments of the present invention, rather than all embodiments, and are only used to illustrate the present invention and should not be regarded as limiting the scope of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0021] In order to more clearly illustrate the technical solutions in the present invention, the following will be described in the form of specific embodiments.

[0022] Example 1 Weigh the following masses of each raw material: 10 g of Rehmannia glutinosa, 6 g of Arnebia euchroma, 9 g of Phellodendron amurense, 10 g of Isatis indigotica, 8 g of Gardenia jasminoides, 6 g of Scutellaria barbata, 6 g of Lobelia chinensis, 7 g of Hedyotis diffusa, 8 g of Platycodon grandiflorum, 6 g of Lonicera japonica, and 3 g of Licorice. After weighing, mix all the raw materials and stir evenly. Then put them into a toothed crusher for crushing, pass through a 60-mesh sieve after crushing, and then use an ultrafine crusher for 90-mesh ultrafine crushing. After the crushing is completed, put the obtained medicinal powder into an aluminum foil bag and seal it for storage.

[0023] Example 2 Weigh the following raw materials by mass: 11g of Rehmannia glutinosa, 8g of Lithospermum erythrorhizon, 10g of Phellodendron amurense, 12g of Isatis indigotica, 9g of Gardenia jasminoides, 7g of Scutellaria barbata, 7g of Lobelia chinensis, 9g of Hedyotis diffusa, 9g of Platycodon grandiflorum, 7g of Lonicera japonica, and 5g of Glycyrrhiza uralensis. After weighing, mix all the raw materials and stir evenly. Then put them into a toothed crusher for crushing. After crushing, sieve through a 60-mesh sieve, and then use a superfine crusher for 90-mesh ultrafine crushing. After the crushing is completed, put the obtained medicinal powder into an aluminum foil bag and seal it for storage.

[0024] Example 3 Weigh the following raw materials by mass: 12g of Rehmannia glutinosa, 10g of Lithospermum erythrorhizon, 12g of Phellodendron amurense, 15g of Isatis indigotica, 10g of Gardenia jasminoides, 8g of Scutellaria barbata, 8g of Lobelia chinensis, 12g of Hedyotis diffusa, 12g of Platycodon grandiflorum, 10g of Lonicera japonica, and 8g of Glycyrrhiza uralensis. After weighing, mix all the raw materials and stir evenly. Then put them into a toothed crusher for crushing. After crushing, sieve through a 60-mesh sieve, and then use a superfine crusher for 90-mesh ultrafine crushing. After the crushing is completed, put the obtained medicinal powder into an aluminum foil bag and seal it for storage.

[0025] Example 4 Weigh the following raw materials by mass: 16g of Rehmannia glutinosa, 11g of Lithospermum erythrorhizon, 18g of Phellodendron amurense, 18g of Isatis indigotica, 13g of Gardenia jasminoides, 10g of Scutellaria barbata, 10g of Lobelia chinensis, 15g of Hedyotis diffusa, 11g of Platycodon grandiflorum, 11g of Lonicera japonica, and 9g of Glycyrrhiza uralensis. After weighing, mix all the raw materials and stir evenly. Then put them into a toothed crusher for crushing. After crushing, sieve through a 60-mesh sieve, and then use a superfine crusher for 90-mesh ultrafine crushing. After the crushing is completed, put the obtained medicinal powder into an aluminum foil bag and seal it for storage.

[0026] Example 5 Weigh the following raw materials by mass: 20g of Rehmannia glutinosa, 12g of Lithospermum erythrorhizon, 21g of Phellodendron amurense, 19g of Isatis indigotica, 14g of Gardenia jasminoides, 12g of Scutellaria barbata, 12g of Lobelia chinensis, 18g of Hedyotis diffusa, 18g of Platycodon grandiflorum, 12g of Lonicera japonica, and 10g of Glycyrrhiza uralensis. After weighing, mix all the raw materials and stir evenly. Then put them into a toothed crusher for crushing. After crushing, sieve through a 60-mesh sieve, and then use a superfine crusher for 90-mesh ultrafine crushing. After the crushing is completed, put the obtained medicinal powder into an aluminum foil bag and seal it for storage.

[0027] Example 6 The difference from Example 3 is only that the raw materials also include 3g of Gypsum Fibrosum.

[0028] Example 7 The difference from Example 3 is only that the raw materials also include 7g of Gypsum Fibrosum.

[0029] Example 8 The difference from Example 3 is only that the raw materials further include 8 g of gypsum.

[0030] Example 9 The difference from Example 3 is only that the raw materials further include 9 g of gypsum.

[0031] Example 10 The difference from Example 3 is only that the raw materials further include 11 g of gypsum.

[0032] Example 11 The difference from Example 3 is only that the raw materials further include 14 g of gypsum.

[0033] Example 12 The difference from Example 3 is only that the raw materials further include 20 g of gypsum.

[0034] Example 13 The difference from Example 3 is only that it further includes 3 g of Ligusticum wallichii.

[0035] Example 14 The difference from Example 3 is only that it further includes 6 g of Ligusticum wallichii.

[0036] Example 15 The difference from Example 3 is only that it further includes 7 g of Ligusticum wallichii.

[0037] Example 16 The difference from Example 3 is only that it further includes 8 g of Ligusticum wallichii.

[0038] Example 17 The difference from Example 3 is only that it further includes 10 g of Ligusticum wallichii.

[0039] Example 18 The difference from Example 3 is only that it further includes 12 g of Ligusticum wallichii.

[0040] Example 19 The difference from Example 3 is only that it further includes 20 g of Ligusticum wallichii.

[0041] Example 20 The difference from Example 3 is only that it further includes 9 g of gypsum and 8 g of Ligusticum wallichii.

[0042] Experimental Example The experimental conditions are as follows: 2,200 piglets born for 2 months were selected and randomly divided into 22 groups on average. Among them, 20 groups were used as the experimental groups, 1 group was used as control group 1, and 1 group was used as control group 2. The 20 experimental groups were respectively fed with feed added with the traditional Chinese medicine formulas of Examples 1-20 (the traditional Chinese medicine formula accounted for 0.5% of the feed composition), control group 1 was fed with feed added with Coptis Detoxification Powder (Coptis Detoxification Powder accounted for 0.5% of the feed composition), and control group 2 was fed with feed without adding any drugs. Among them, each pig was fed 1,000 g of feed per day for 60 consecutive days.

[0043] The experimental results are as follows: On the 10th day of feeding, African swine fever infections occurred successively in nearby pig farms. To avoid infection, the pig farm in this experimental area strengthened the biosafety prevention measures, monitored the health of 2,200 piglets every day, and eliminated the infected pigs.

[0044] After the experiment ended, the situations of each group were shown in Table 1.

[0045] Table 1 Experimental Results It can be seen from the above table that the preventive effective rate of the experimental group was above 78%, the preventive effective rate of control group 1 was only 51%, and the preventive effective rate of control group 2 was only 24%. This shows that the traditional Chinese medicine formula of the present invention is far superior to control group 1 that simply uses Coptis Detoxification Powder and control group 2 that does not add drugs. The traditional Chinese medicine formula of the present invention can play a good preventive role against African swine fever.

[0046] By comparing Examples 6-12, it can be seen that the traditional Chinese medicine formula of Example 9 had the highest preventive effective rate against African swine fever. This may be because too little gypsum was added, resulting in insufficient heat-clearing effect, being unable to effectively inhibit virus reproduction and affecting the prevention and treatment effect. And it may lead to imbalance in compatibility and reduce the overall medicinal effect. If too much gypsum is added, the medicinal property will be too strong, easily damaging the spleen and stomach, causing symptoms such as diarrhea and abdominal pain, and affecting the normal digestion and absorption of pigs. At the same time, it may inhibit the effect of rehmannia glutinosa in nourishing yin and blood, making the overall formula lose balance and reducing the prevention and treatment effect.

[0047] Comparing Examples 13 - 19, it can be seen that the traditional Chinese medicine formula in Example 16 has the highest effective rate in preventing African swine fever. This may be because when the amount of Chuanxiong is too small, it cannot effectively assist Platycodon grandiflorum in exerting its function of dispersing the lung qi, and it reduces the synergistic effect with Gardenia jasminoides, failing to achieve the effect of enhancing heat-clearing and detoxifying. Additionally, too little Chuanxiong cannot balance the cold nature of Scutellaria barbata, Lobelia chinensis, etc., resulting in the prescription being too cold, which is not conducive to maintaining the physical condition of pigs and may even damage the spleen and stomach. When the amount of Chuanxiong added is too much, it may mask the function of Platycodon grandiflorum in dispersing the lung qi, leading to poor effect of dispersing the lung qi, and it may make the nature of the whole prescription tend to be hot, which is not conducive to heat-clearing and detoxifying, and may even cause more heat pathogens in the pigs' bodies, being not conducive to the treatment of African swine fever.

[0048] Comparing Examples 3, 9, 16, and 20, it can be seen that the effect of Example 3 is the worst and the effect of Example 20 is the best. This shows that adding Gypsum fibrosum and Chuanxiong in the formula can effectively enhance the prevention and treatment effect of African swine fever and improve the immunity of the pig herd.

[0049] Verification Example Case 1: A farmer in Shijiazhuang purchased 400 fattening pigs from outside. After one month of feeding, some suspicious pigs showed anorexia and fever. On August 9, 2024, the African swine fever nucleic acid test in the laboratory was positive with a CT value of 37.07. The suspicious pigs were culled, and this traditional Chinese medicine formula (adding the traditional Chinese medicine formula of Example 20 to the feed at 0.5%) was fed. After August 22, 2024, no pigs got sick, and the nucleic acid test was negative again.

[0050] Case 2: A pig farmer in Anyang raised more than 80 sows and more than 600 fattening pigs. Unfortunately, they were infected with African swine fever in August 2024. The nucleic acid test was positive with a CT value of 32.8. After feeding this traditional Chinese medicine formula (adding the traditional Chinese medicine formula of Example 20 to the feed at 0.5%) for 4 days, the feed intake increased. After 14 days, there were no new cases of illness, and they remained healthy afterwards.

[0051] Case 3: A farmer in Kaiyuan City, after learning that the neighboring pig farm was infected with African swine fever, added this traditional Chinese medicine formula (adding the traditional Chinese medicine formula of Example 20 to the feed at 0.5%) to the feed during feeding. After continuous feeding for two months, the antibody test was positive, indicating being infected but not getting sick.

[0052] In conclusion, the traditional Chinese medicine formula of this application can significantly improve the immune ability of animals, enhance the vital qi of the body and the disease resistance of the body, thereby effectively blocking the ways for viruses such as African swine fever to invade animals. Using this traditional Chinese medicine formula to prevent African swine fever, the total effective rate can reach more than 78%.

[0053] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A Chinese medicine formula for preventing African swine fever, characterized in that: The invention comprises the following raw materials by weight: 10-20 parts of raw rehmannia, 6-12 parts of lithospermum, 9-21 parts of phellodendron, 10-19 parts of isatis indigotica, 8-14 parts of gardenia, 6-12 parts of scutellaria barbata, 6-12 parts of lobelia, 7-18 parts of herba scutellariae, 8-18 parts of platycodon, 6-12 parts of honeysuckle and 3-10 parts of liquorice.

2. The Chinese medicine formula for preventing African swine fever according to claim 1, characterized in that: Calculated by mass, it also includes: 7-14 parts of gypsum.

3. The Chinese medicine formula for preventing African swine fever according to claim 1, characterized in that: Calculated by weight, the invention also includes 6-12 parts of Chuanxiong.

4. The Chinese medicine formula for preventing African swine fever according to claim 1, characterized in that: The invention comprises the following raw materials by weight: 11-16 parts of raw rehmannia, 8-11 parts of lithospermum, 10-18 parts of phellodendron, 12-18 parts of isatis indigotica, 8-11 parts of gypsum, 9-13 parts of gardenia, 7-10 parts of chuanxiong, 7-10 parts of scutellaria barbata, 7-10 parts of lobelia, 9-15 parts of scutellaria baicalensis, 9-11 parts of platycodon, 7-11 parts of honeysuckle and 5-9 parts of liquorice.

5. The Chinese medicine formula for preventing African swine fever according to claim 4, characterized in that: The invention comprises the following raw materials by weight: 12 parts of raw rehmannia, 10 parts of lithospermum officinale, 12 parts of phellodendron, 15 parts of isatis indigotica, 9 parts of gypsum, 10 parts of gardenia, 8 parts of ligusticum chuanxiong, 8 parts of scutellaria barbata, 8 parts of lobelia, 12 parts of herba scutellariae, 12 parts of platycodon grandiflorum, 10 parts of honeysuckle and 8 parts of liquorice.

6. A method for preparing a Chinese medicine formula for preventing African swine fever, characterized in that: For preparing the traditional Chinese medicine formula according to any one of claims 1 to 5, the method comprising: Mix all the ingredients and stir evenly; The mixed raw materials are crushed to obtain the traditional Chinese medicine formula.

7. The preparation method according to claim 6, characterized in that: The step of crushing the mixed raw materials comprises: The mixed raw materials are initially crushed; Filter the raw materials after primary crushing using a 60-mesh sieve; The raw materials obtained after filtration were pulverized using an ultrafine pulverizer.

8. A feed composition for preventing African swine fever, characterized in that: include: A feed and a Chinese medicine formula according to any one of claims 1 to 5, wherein the Chinese medicine formula accounts for 0.2% to 0.5% of the feed composition.

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