Biopharmaceutical three-dosage-form integrated packaging equipment

The visual inspection and negative pressure airflow of the integrated packaging equipment for three dosage forms of biopharmaceuticals simultaneously adsorb foreign matter, solving the sealing problem caused by foreign matter during the pill filling process, achieving simultaneous detection of pills and foreign matter, and improving packaging efficiency and drug stability.

CN120717030AInactive Publication Date: 2025-09-30SHANXI KANGHUI ZHONGTIAN PHARM TECH CO LTD
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Patent Information

Application Number
CN202511247304.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-03
Publication Date
2025-09-30
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the existing technology, foreign matter is easily present in the three-dose integrated blister during the pill filling process, resulting in poor sealing, affecting the stability and shelf life of the drugs. At the same time, pill detection and foreign matter detection are carried out separately, which prolongs the packaging time and reduces efficiency.

Method used

A three-dose integrated packaging device for biopharmaceuticals is used to perform preliminary inspection of pills through a visual detector. Combined with negative pressure airflow and a dust removal seat to synchronously adsorb foreign matter, this allows for simultaneous inspection of pills and foreign matter. An electric push rod and slide are used to adjust the inspection position, improving inspection efficiency.

Benefits of technology

It achieves simultaneous detection of pills and foreign objects, shortens packaging time, improves overall packaging efficiency, and ensures the sealing and storage stability of pills.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of blister packaging, and discloses biopharmaceutical three-dosage-form integrated packaging equipment which comprises a machine table, a guide plate is arranged on the machine table, a mounting bottom plate is arranged above the guide plate, a visual detector is arranged on one side of the guide plate, and a plurality of dust removal seats distributed at equal intervals are arranged on the mounting bottom plate; a filter plate is fixed in the dust removal seat, a top plate is arranged below the filter plate, a circulation plate and two wedge-shaped abutting plates are arranged above the filter plate, the circulation plate abuts against the wedge-shaped abutting plates, abutting blocks are connected to the lower portions of the wedge-shaped abutting plates in a sliding mode, and limiting blocks are connected to the filter plate in a sliding mode; according to the pill packaging machine, pill detection and foreign matter detection are completed through one detection station, the detection efficiency is improved, the pill packaging time is shortened, and the overall packaging efficiency is improved.
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Description

Technical Field

[0001] The present invention relates to the technical field of blister packaging, in particular to a three-dose integrated packaging device for biopharmaceuticals. Background Art

[0002] The three-dose integrated blister packs three different specifications of products onto an aluminum-plastic board. It can be packaged according to daily or multiple dosages, making it easy to carry and take. This packaging method is suitable for middle-aged and elderly people and people on long-term business trips. The three-dose integrated packaging equipment can simultaneously pack different pills onto a single board and is equipped with a special three-shaped drug feeder that can simultaneously add three different pills. The three-dose integrated packaging equipment can realize the functions of blister forming, blister inspection, drug filling, vacuum foreign body removal, pre-sealing inspection, and roller heat sealing packaging.

[0003] During the pill filling process of the three-dose integrated blister, foreign matter will be filled into the blister along with the pills. The presence of foreign matter may destroy the sealing structure of the blister, resulting in poor sealing of the package, thereby affecting the stability and shelf life of the medicine, and secondly affecting the physical protection performance of the package, which needs to be cleaned after the filling is completed. In the prior art, after the blister-formed pills are put in, it is necessary to use a detection equipment to detect the pills in the blister. After the detection is completed, a vacuum adsorption device is used to align with the blister to adsorb and remove the foreign matter. After the foreign matter is adsorbed and removed, it is necessary to use another detection device to detect foreign matter. The detection of pills and the detection of foreign matter are carried out separately, which will extend the time of pill packaging and greatly affect the efficiency of packaging. Summary of the Invention

[0004] The present invention provides a biopharmaceutical three-dose integrated packaging device, which is capable of completing the detection of pills and foreign matter through a single detection station, thereby improving the detection efficiency, shortening the time for pill packaging, and enhancing the overall packaging efficiency. It solves the problem mentioned in the above background technology that after the detection is completed, a vacuum adsorption device is used to align the blister to adsorb and remove foreign matter. After the foreign matter is adsorbed and removed, another detection device is required to perform foreign matter detection. The detection of pills and the detection of foreign matter are performed separately, which will prolong the time for pill packaging and greatly affect the packaging efficiency.

[0005] The present invention provides the following technical solution: a biopharmaceutical three-dose integrated packaging device, comprising a machine platform, a guide plate provided on the machine platform, a mounting base plate provided above the guide plate, a visual detector provided on one side of the guide plate, a plurality of equally spaced dust removal seats provided on the mounting base plate, a filter plate fixed in the dust removal seat, a top plate provided below the filter plate, a circulation plate and two wedge-shaped interference plates provided above the filter plate, the circulation plate and the wedge-shaped interference plates being in conflict with each other, a interference block being slidably connected to the bottom of the wedge-shaped interference plate, and a limit block being slidably connected to the filter plate; A first interference rod is fixed on the wedge-shaped interference plate, and movable seats are provided on both sides of the dust removal seat. Deflectable claws are provided on the movable seats.

[0006] As an optional solution for the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, a hollow rod is fixed on the top plate, the hollow rod is slidably connected to the filter plate, a first spring is connected between the circulation plate and the hollow rod, and a fourth spring is connected between the wedge-shaped contact plate and the contact block.

[0007] As an optional solution of the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, the first resistance rod is elastically connected to the dust removal seat through a second spring, one end of the first resistance rod is in resistance to a seesaw, a rotating rod is fixed on the seesaw, a first strip plate is fixed on one side of the dust removal seat, the first strip plate is rotatably connected to the rotating rod, and a first torsion spring is connected between the first strip plate and the rotating rod.

[0008] As an optional solution for the three-dose integrated packaging equipment of biopharmaceuticals described in the present invention, a second strip plate is fixed on the movable seat, a guide rod is fixed on the dust removal seat, the guide rod is elastically connected to the second strip plate through a third spring, and the second strip plate is in conflict with the first strip plate.

[0009] As an optional solution for the three-dose integrated packaging equipment of biopharmaceuticals described in the present invention, wherein: the movable seat is rotatably connected to a rotating shaft, one end of the clamping claw is fixed on the rotating shaft, and a second torsion spring is connected between the rotating shaft and the movable seat, rectangular notches are opened on both sides of the dust removal seat, and the clamping claw is located in the rectangular notch.

[0010] As an optional solution for the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, a connecting pipe is fixed above the dust removal seat, a first valve is fixed on the connecting pipe, a branch pipe is fixed on the connecting pipe, a second valve is fixed on the branch pipe, an electric push rod is fixed on the machine platform, and the piston rod of the electric push rod is fixedly connected to the mounting base plate.

[0011] As an optional solution to the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, wherein: a blister forming device is provided on the machine platform, a blister filling device is provided on one side of the blister forming device, an electric slide is fixed on the machine platform, the visual detector is provided on the moving end of the electric slide, and a roller mold and a heat sealing roller are respectively provided on one side of the mounting base, the roller mold and the heat sealing roller are both rotatably connected to the machine platform, and the roller mold is opposite to the heat sealing roller.

[0012] As an optional solution to the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, a second resistance rod is slidably connected to the movable seat, and a servo motor is fixed on one side of the movable seat, a cam is fixed on the motor shaft of the servo motor, and a limiting ring is fixed on the second resistance rod.

[0013] As an optional solution for the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, the circulation plate is provided with a plurality of equally spaced circulation holes, a cover plate is provided above the circulation holes, a rotating frame is fixed to the circulation plate, the cover plate is rotatably connected to the rotating frame, and a third torsion spring is connected between the cover plate and the rotating frame.

[0014] As an optional solution of the three-dose integrated packaging equipment for biopharmaceuticals described in the present invention, a conical contact head is fixed under the circulation plate, the conical contact head is slidably connected to the hollow rod, and the lower end of the conical contact head is in contact with two trapezoidal contact blocks, the trapezoidal contact blocks are elastically connected to the hollow rod through a fifth spring, a sliding bracket is fixed on the filter plate, one end of the trapezoidal contact block is in contact with a strip block, the strip block is elastically connected to the sliding bracket through a sixth spring, and a wedge-shaped groove is provided on the strip block.

[0015] The present invention has the following beneficial effects: 1. In this biopharmaceutical three-dose integrated packaging equipment, the visual detector will first conduct a preliminary inspection of the pills in the three-dose blisters to determine whether there is any shortage of material in the blisters. When the installation base is moved down, the dust removal seat will be accurately aligned and fitted on the blister mouth that has completed the preliminary inspection. The connecting pipe is connected to the dust collection equipment, and through the negative pressure airflow, the foreign matter in the pills and blisters will be simultaneously adsorbed into the dust removal seat. At this time, the role of the filter plate is crucial. It can effectively prevent the pills from being sucked out of the dust removal seat, and the foreign matter will flow from the dust removal seat into the connecting pipe and be discharged under the action of the negative pressure airflow, thereby reducing the amount of foreign matter in the dust removal seat. At the same time, when the pills are adsorbed into the dust removal seat, they can come into contact with the top plate, prompting the top plate to drive the circulation plate to move up; After the foreign matter in the blister is adsorbed, the height of the dust removal seat can be adjusted by the electric push rod to form a height difference between the dust removal seat and the blister. The detection position of the visual detector can be adjusted by the electric slide to achieve the purpose of foreign matter detection on the blister after the foreign matter adsorption is completed. Through one detection station, the detection of pills and foreign matter can be completed, which improves the detection efficiency, shortens the time of pill packaging, and improves the overall packaging efficiency.

[0016] 2. In this biopharmaceutical three-dose integrated packaging equipment, movable seats are set on both sides of the dust removal seat to facilitate the installation of the claws. When the pills are adsorbed into the dust removal seat, the claws can be moved into the dust removal seat to limit the pills, which can prevent the pills from falling into the blister when adsorbing foreign matter, affecting the effect of foreign matter adsorption; When the circulation plate moves up, it can achieve the purpose of interfering with the two wedge-shaped interference plates, so that the first interference rod can push the seesaw plate to deflect during the movement, so that the deflection of the seesaw plate interferes with the second strip plate fixed on the moving seat, prompting the second strip plate to drive the moving seat and the clamping claw to move synchronously, so that the clamping claw can automatically limit the pills in the dust removal seat. At the same time, the retractable interference block on the wedge-shaped interference plate can interfere with the limit block during the movement. When the movement stops, the wedge-shaped interference plate can be limited, so that the clamping claw can always maintain a limited state during the foreign matter adsorption process, thereby further improving the limiting effect. Through the cooperation of the servo motor, the cam and the second resistance rod, when the servo motor drives the cam to rotate and resist the second resistance rod, the second resistance rod and the claw can be reciprocated, so that the claw is prompted to swing back and forth in the dust removal seat. The reciprocating suction method is used to make the pills move continuously in the dust removal seat, which can further improve the effect of foreign matter suction.

[0017] 3. In the integrated packaging equipment for three dosage forms of biopharmaceuticals, compressed gas is conveniently ventilated into the dust removal seat through the branch pipe, and a cover plate is provided for the circulation hole on the circulation plate. When the negative pressure air flow stops flowing, the cover plate is automatically deflected and reset under the action of elastic force to seal the circulation hole, so that the circulation plate can be pushed to slide vertically down in the dust removal seat when the branch pipe is ventilated. On the one hand, the circulation plate can drive the two trapezoidal interference blocks of the conical interference head to interfere with each other, so that the two trapezoidal interference blocks push the sliding bracket of the strip block on the filter plate to move horizontally, and the wedge-shaped groove on the strip block moves to the bottom of the limit block, which is convenient for the limit block to retract and release the limit on the interference block; on the other hand, the downward movement of the circulation plate can release the conflict with the wedge-shaped interference plate. After the interference block is released from the limit, the wedge-shaped interference plate can be reset, and the claw can release the limit on the pills through linkage, so that the cleaned pills can automatically fall into the clean blister. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is one of the three-dimensional structural diagrams of the present invention.

[0019] Figure 2 This is the second schematic diagram of the three-dimensional structure of the present invention.

[0020] Figure 3 It is a schematic structural diagram of the dust removal seat of the present invention.

[0021] Figure 4 It is a cross-sectional view of the dust removal seat structure of the present invention.

[0022] Figure 5 This is one of the schematic diagrams of the internal structure of the dust removal seat of the present invention.

[0023] Figure 6 This is the second schematic diagram of the internal structure of the dust removal seat of the present invention.

[0024] Figure 7 It is a schematic diagram of the strip block structure of the present invention.

[0025] Figure 8 for Figure 4 A partial enlarged view of point A in the middle.

[0026] Figure 9 for Figure 5 A partial enlarged view of point B in the middle.

[0027] Figure 10 for Figure 6 A partial enlarged view of point C in the middle.

[0028] Figure 11 It is a schematic diagram of the height adjustment structure of the limit block of the present invention.

[0029] In the figure: 1, machine table; 2, guide plate; 3, mounting base; 4, dust removal seat; 5, filter plate; 6, top plate; 7, circulation plate; 8, wedge-shaped contact plate; 9, contact block; 10, first contact rod; 11, moving seat; 12, claw; 13, branch pipe; 14, hollow rod; 15, sixth spring; 16, wedge-shaped groove; 17, first spring; 18, second spring; 19, seesaw; 20, rotating rod; 21, first strip plate; 22, first torsion spring; 23, second strip plate; 24, guide rod; 25, third spring; 26, rotating shaft; 27, second torsion spring; 28, rectangular notch; 29, connecting pipe; 30, first Valve; 31. Second valve; 32. Blister forming equipment; 33. Blister filling equipment; 34. Electric slide; 341. Visual detector; 35. Roller mold; 36. Heat sealing roller; 37. Fourth spring; 38. Limit block; 39. Second contact rod; 40. Servo motor; 41. Cam; 42. Limit ring; 43. Flow hole; 44. Cover plate; 45. Rotating frame; 46. Third torsion spring; 47. Conical contact head; 48. Trapezoidal contact block; 49. Fifth spring; 50. Sliding bracket; 51. Bar block; 52. Electric push rod; 53. Piston cylinder; 54. Piston plate; 55. Piston rod; 56. Seventh spring. DETAILED DESCRIPTION

[0030] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0031] For example 1, please refer to Figures 1 to 11 A biopharmaceutical three-dose integrated packaging device includes a machine platform 1, a guide plate 2 is provided on the machine platform 1, a mounting base plate 3 is provided above the guide plate 2, and a visual detector 341 is provided on one side of the guide plate 2, a plurality of equally spaced dust removal seats 4 are provided on the mounting base plate 3, a filter plate 5 is fixed in the dust removal seat 4, a top plate 6 is provided below the filter plate 5, and a circulation plate 7 and two wedge-shaped contact plates 8 are provided above the filter plate 5, respectively, and the circulation plate 7 conflicts with the wedge-shaped contact plates 8, and a contact block 9 is slidably connected to the bottom of the wedge-shaped contact plate 8, and a limit block 38 is slidably connected to the filter plate 5; A first resistance rod 10 is fixed on the wedge-shaped resistance plate 8 , and a movable seat 11 is provided on both sides of the dust removal seat 4 , and a deflectable claw 12 is provided on the movable seat 11 .

[0032] A hollow rod 14 is fixed on the top plate 6 , and the hollow rod 14 is slidably connected to the filter plate 5 . A first spring 17 is connected between the circulation plate 7 and the hollow rod 14 , and a fourth spring 37 is connected between the wedge-shaped contact plate 8 and the contact block 9 .

[0033] The first interference rod 10 is elastically connected to the dust removal seat 4 through the second spring 18. One end of the first interference rod 10 is in contact with a rocker 19, and a rotating rod 20 is fixed on the rocker 19. A first strip plate 21 is fixed to one side of the dust removal seat 4. The first strip plate 21 is rotatably connected to the rotating rod 20, and a first torsion spring 22 is connected between the first strip plate 21 and the rotating rod 20.

[0034] A second strip plate 23 is fixed on the movable seat 11 , and a guide rod 24 is fixed on the dust removal seat 4 . The guide rod 24 is elastically connected to the second strip plate 23 via a third spring 25 , and the second strip plate 23 is in conflict with the first strip plate 21 .

[0035] A connecting pipe 29 is fixed above the dust removal seat 4, a first valve 30 is fixed on the connecting pipe 29, a branch pipe 13 is fixed on the connecting pipe 29, a second valve 31 is fixed on the branch pipe 13, an electric push rod 52 is fixed on the machine 1, and the piston rod of the electric push rod 52 is fixedly connected to the mounting base 3.

[0036] A blister forming device 32 is provided on the machine 1, and a blister filling device 33 is provided on one side of the blister forming device 32. An electric slide 34 is fixed on the machine 1, and a visual detector 341 is provided on the moving end of the electric slide 34. A roller mold 35 and a heat sealing roller 36 are respectively provided on one side of the mounting base 3. The roller mold 35 and the heat sealing roller 36 are both rotatably connected to the machine 1, and the roller mold 35 is opposite to the heat sealing roller 36.

[0037] refer to Figures 1 to 6 First, the blister forming device 32 on the machine 1 preheats and stretches the plastic medicine plate, and forms three different blisters by compressed air blowing. The blister filling device 33 discharges the materials of the three dosage forms respectively by three feeders in sequence, time periods and different guides to prevent the occurrence of misplaced discharge and consolidation. The filled blisters move on the guide plate 2, and the visual detector 341 detects the lack of material on the pills filled in the blisters. At the same time, the electric push rod 52 adjusts the height of the mounting base 3, prompting the mounting base 3 to move down and fit on the blister, so that several dust removal seats 4 on the mounting base 3 can be aligned with the three different types of blister ports at the same time. When the connecting pipe 29 is connected to the dust collection device, the first valve 30 is opened and the second valve 31 is closed, so that the negative pressure airflow enters the dust removal seat 4. Through the cooperation of the circulation plate 7 and the filter plate 5, the pills in the blister can be adsorbed into the dust removal seat 4 and contact with the top plate 6. The adsorption force of this process is the strongest The second spring 18 is used to store force, and the first friction rod 10 is used to push the first friction rod 10 to slide on the dust collecting seat 4. The second spring 18 is used to store force, and the first friction rod 10 is used to push the rocker 19 to deflect when the first friction rod 10 moves horizontally, so that the rotating rod 20 on the rocker 19 rotates on the first strip plate 21. The first torsion spring 22 stores force, and the rocker 19 is deflected to push the second strip plate 23 to move horizontally on the guide rod 24. The third spring 25 stores force, so that the two moving seats 11 simultaneously drive the claws 12 to insert into the dust collecting seat 4 from the rectangular notches 28 opened on both sides of the dust collecting seat 4. The two claws 12 are close to each other, which can achieve the purpose of limiting the pills and prevent the pills from falling out of the dust collecting seat 4 during the dust collection process. During the movement of the wedge-shaped contact plate 8, the purpose of driving the contact block 9 to contact the limit block 38 can be achieved, prompting the contact block 9 to retract into the wedge-shaped contact plate. After the contact with the limit block 38 is released, the contact block 9 is restored. The fourth spring 37 first accumulates force and then releases the elastic force. At this time, the contact block 9 is located on one side of the limit block 38, which can limit the wedge-shaped contact plate 8, prompting the claw 12 to always maintain a limited state during the foreign matter adsorption process, further improving the limiting effect.

[0038] The height of the mounting base 3 is adjusted again by the electric push rod 52, so that the mounting base 3 drives the dust removal seat 4 to move upward, forming a certain height difference between the dust removal seat 4 and the blister, and then the electric slide 34 drives the visual detector 341 to move horizontally to detect foreign matter in the blister. Through one detection station, the detection of pills and foreign matter can be completed, thereby improving the detection efficiency, shortening the time of pill packaging, and improving the packaging efficiency.

[0039] Example 2: This example is an improvement based on Example 1. For details, please refer to Figures 1 to 11 The movable seat 11 is rotatably connected to a rotating shaft 26, one end of the claw 12 is fixed on the rotating shaft 26, and a second torsion spring 27 is connected between the rotating shaft 26 and the movable seat 11. Rectangular slots 28 are opened on both sides of the dust removal seat 4, and the claw 12 is located in the rectangular slot 28.

[0040] A second resisting rod 39 is slidably connected to the movable base 11 , and a servo motor 40 is fixed to one side of the movable base 11 . A cam 41 is fixed to the motor shaft of the servo motor 40 , and a limiting ring 42 is fixed to the second resisting rod 39 .

[0041] refer to Figures 6 to 10 In order to improve the effect of removing impurities on the pills in the dust removal seat 4, the servo motor 40 fixed on the moving seat 11 drives the cam 41 to rotate, so that the second contact rod 39 is intermittently contacted by the cam 41, which can push the claw 12 to deflect on the moving seat 11, and the rotating shaft 26 rotates on the moving seat 11. The second torsion spring 27 stores force and adjusts the vacuum adsorption force at the same time. The reciprocating suction method is adopted. The deflection of the claw 12 allows the pills to move continuously in the dust removal seat 4, which can reduce the adsorption dead angle and further improve the effect of foreign matter removal. Secondly, in the process of detecting the lack of material on the pills, defects such as foreign matter on the pills will also be detected synchronously. The claw 12 is used to move the pills, which can have the effect of adjusting the posture of the pills. When the visual detector 341 detects the pills for the second time during the reset process, the detection dead angle can be reduced.

[0042] The limiting ring 42 fixed on the second resisting rod 39 can prevent the second resisting rod 39 from falling off the movable seat 11 .

[0043] Example 3: This example is an improvement based on Example 1. For details, please refer to Figures 1 to 11 The circulation plate 7 is provided with a number of equally distributed circulation holes 43, and a cover plate 44 is provided above the circulation hole 43. A rotating frame 45 is fixed on the circulation plate 7, and the cover plate 44 is rotatably connected to the rotating frame 45, and a third torsion spring 46 is connected between the cover plate 44 and the rotating frame 45.

[0044] A conical contact head 47 is fixed below the circulation plate 7, and the conical contact head 47 is slidably connected to the hollow rod 14, and the lower end of the conical contact head 47 abuts against two trapezoidal contact blocks 48, and the trapezoidal contact block 48 is elastically connected to the hollow rod 14 through a fifth spring 49. A sliding bracket 50 is fixed to the filter plate 5, and one end of the trapezoidal contact block 48 abuts against a strip block 51, which is elastically connected to the sliding bracket 50 through a sixth spring 15, and a wedge-shaped groove 16 is provided on the strip block 51.

[0045] refer to Figures 4 to 9 When the impurities on the pills are adsorbed, the electric push rod 52 adjusts the height of the mounting base 3 so that the dust removal seat 4 moves downward. During the movement, the second valve 31 on the branch pipe 13 is opened, and the first valve 30 on the connecting pipe 29 is closed. The cover plate 44 provided with the flow hole 43 on the circulation plate 7 can be automatically deflected on the rotating frame 45 under the influence of suction during the adsorption and dust removal process. The third torsion spring 46 stores force to open the flow hole 43 to facilitate the discharge of impurities. After the vacuum adsorption is completed, the third torsion spring 46 releases the elastic force to automatically reset the cover plate 44 and close the flow hole 43. The branch pipe 13 is ventilated to push the circulation plate 7 downward. At this time, the pill rests between the top plate 6 and the claw 12, so that the circulation plate 7 drives the conical friction. The head 47 slides in the hollow rod 14, the first spring 17 stores force, the conical contact head 47 and the two trapezoidal contact blocks 48 simultaneously contact each other, causing the two trapezoidal contact blocks 48 to be subject to contact and move horizontally on the hollow rod 14, the fifth spring 49 stores force, which can achieve the purpose of the trapezoidal contact block 48 pushing the bar block 51 to slide on the sliding bracket 50, and the sixth spring 15 stores force, causing the wedge-shaped groove 16 opened on the bar block 51 to be located directly below the limit block 38, making it convenient for the limit block 38 to slide into the wedge-shaped groove 16, thereby releasing the limit on the contact block 9, so that after the second spring 18 releases the elastic force, the wedge-shaped contact plate 8 can be reset, and the claw 12 can be linked to release the limit on the pills, so that the cleaned pills can automatically fall into the clean blister.

[0046] During packaging, the blister can be stuck on the roller die 35. When the blister containing the tablets and the aluminum foil passes between the roller die 35 and the heat-sealing roller 36, the two rollers are in contact in a straight line. The small contact area and the relative pressure are large, which can improve the heat-sealing effect. The heat-sealing roller 36 is equipped with a stainless steel heating tube for heating the heat-sealing roller 36. The heating tube is controlled by an automatic temperature control system to keep a constant temperature.

[0047] Example 4: This example is an improvement made on the basis of Example 3. For details, please refer to Figures 1 to 11The present application also provides a position adjustment structure of the limit block 38, including a piston cylinder 53, the piston cylinder 53 is fixed on the filter plate 5, a piston plate 54 is slidably connected to the piston cylinder 53, a piston rod 55 is fixed to the piston plate 54, one end of the piston rod 55 is fixedly connected to the limit block 38, and the piston rod 55 is elastically connected to the piston cylinder 53 via a seventh spring 56; When the limit block 38 needs to release the limit on the interference block 9, air is ventilated in the piston cylinder 53, prompting the piston plate 54 to drive the piston rod 55 to move downward in the piston cylinder 53. The seventh spring 56 accumulates force, causing the limit block 38 to move downward synchronously on the filter plate 5, thereby releasing the limit on the interference block 9.

[0048] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0049] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principles of the present invention. These improvements and modifications should also be regarded as within the scope of protection of the present invention.

Claims

1. A biopharmaceutical three-dose integrated packaging device, comprising a machine (1), characterized in that: The machine (1) is provided with a guide plate (2), a mounting base plate (3) is provided above the guide plate (2), and a visual detector (341) is provided on one side of the guide plate (2), a plurality of equally spaced dust removal seats (4) are provided on the mounting base plate (3), a filter plate (5) is fixed inside the dust removal seat (4), a top plate (6) is provided below the filter plate (5), and a circulation plate (7) and two wedge-shaped contact plates (8) are provided above the filter plate (5), respectively, and the circulation plate (7) contacts the wedge-shaped contact plate (8), a contact block (9) is slidably connected below the wedge-shaped contact plate (8), and a limit block (38) is slidably connected to the filter plate (5); A first contact rod (10) is fixed on the wedge-shaped contact plate (8), and movable seats (11) are provided on both sides of the dust removal seat (4). Deflectable claws (12) are provided on the movable seats (11).

2. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: A hollow rod (14) is fixed on the top plate (6), and the hollow rod (14) is slidably connected to the filter plate (5). A first spring (17) is connected between the circulation plate (7) and the hollow rod (14), and a fourth spring (37) is connected between the wedge-shaped contact plate (8) and the contact block (9).

3. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: The first abutting rod (10) is elastically connected to the dust removal seat (4) via a second spring (18); one end of the first abutting rod (10) abuts against a seesaw (19); a rotating rod (20) is fixed to the seesaw (19); a first strip plate (21) is fixed to one side of the dust removal seat (4); the first strip plate (21) is rotatably connected to the rotating rod (20); and a first torsion spring (22) is connected between the first strip plate (21) and the rotating rod (20).

4. The biopharmaceutical three-dose integrated packaging equipment according to claim 3, characterized in that: A second strip plate (23) is fixed on the movable seat (11), and a guide rod (24) is fixed on the dust removal seat (4). The guide rod (24) is elastically connected to the second strip plate (23) via a third spring (25), and the second strip plate (23) is in conflict with the first strip plate (21).

5. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: The movable seat (11) is rotatably connected to a rotating shaft (26), one end of the clamping claw (12) is fixed to the rotating shaft (26), and a second torsion spring (27) is connected between the rotating shaft (26) and the movable seat (11). Rectangular notches (28) are provided on both sides of the dust removal seat (4), and the clamping claw (12) is located in the rectangular notch (28).

6. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: A connecting pipe (29) is fixed above the dust removal seat (4), a first valve (30) is fixed on the connecting pipe (29), a branch pipe (13) is fixed on the connecting pipe (29), a second valve (31) is fixed on the branch pipe (13), an electric push rod (52) is fixed on the machine (1), and a piston rod of the electric push rod (52) is fixedly connected to the mounting base plate (3).

7. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: The machine (1) is provided with a blister forming device (32), a blister filling device (33) is provided on one side of the blister forming device (32), an electric slide (34) is fixed on the machine (1), the visual detector (341) is provided on the moving end of the electric slide (34), and a roller mold (35) and a heat sealing roller (36) are provided on one side of the mounting base (3), the roller mold (35) and the heat sealing roller (36) are both rotatably connected to the machine (1), and the roller mold (35) is opposite to the heat sealing roller (36).

8. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: A second resisting rod (39) is slidably connected to the movable seat (11), and a servo motor (40) is fixed on one side of the movable seat (11). A cam (41) is fixed on the motor shaft of the servo motor (40), and a limiting ring (42) is fixed on the second resisting rod (39).

9. The biopharmaceutical three-dose integrated packaging equipment according to claim 1, characterized in that: The circulation plate (7) is provided with a plurality of equally spaced circulation holes (43), a cover plate (44) is provided above the circulation holes (43), a rotating frame (45) is fixed on the circulation plate (7), the cover plate (44) is rotatably connected to the rotating frame (45), and a third torsion spring (46) is connected between the cover plate (44) and the rotating frame (45).

10. The biopharmaceutical three-dose integrated packaging equipment according to claim 2, characterized in that: A conical contact head (47) is fixed below the circulation plate (7), and the conical contact head (47) is slidably connected to the hollow rod (14). The lower end of the conical contact head (47) contacts two trapezoidal contact blocks (48), and the trapezoidal contact blocks (48) are elastically connected to the hollow rod (14) via a fifth spring (49). A sliding bracket (50) is fixed to the filter plate (5), and one end of the trapezoidal contact block (48) contacts a strip block (51), and the strip block (51) is elastically connected to the sliding bracket (50) via a sixth spring (15). A wedge-shaped groove (16) is provided on the strip block (51).