Hippophae rhamnoides health-care paste for regulating spleen and stomach and preparation method thereof

Through the preparation of seabuckthorn nourishing paste, combining traditional Chinese medicine with modern prebiotics, the problem of complex or slow effect of existing Chinese medicine prescriptions has been solved, and a simple and effective spleen and stomach conditioning and gastrointestinal repair effect has been achieved.

CN120789197APending Publication Date: 2025-10-17BEIJING CHENS AI YISHENG HEALTH MANAGEMENT CO LTD
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Patent Information

Application Number
CN202511002700.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-21
Publication Date
2025-10-17

AI Technical Summary

Technical Problem

Existing Chinese herbal prescriptions have problems with regulating the spleen and stomach, such as complex composition or slow effect. Modern lifestyle and Helicobacter pylori infection have aggravated the incidence of spleen and stomach diseases. It is necessary to develop Chinese herbal compound prescriptions with simple formula and clear efficacy.

Method used

The seabuckthorn nourishing paste is prepared by using seabuckthorn and Poria as the main medicines, coix seed, white hyacinth bean and yam as the auxiliary medicines, hawthorn, chicken gizzard lining, malt, amomum villosum and tangerine peel as the adjuvant medicines, and jujube and oligomaltodextrose as the guiding medicines. The seabuckthorn nourishing paste is prepared by decoction and paste collection technology, and combined with modern prebiotic ingredients to achieve multi-target regulation of spleen and stomach function.

Benefits of technology

It can significantly regulate the spleen and stomach, restore the transportation and transformation function of the middle burner, improve symptoms such as indigestion and acid reflux, enhance gastric mucosal repair, and form a dual mechanism of "microecological conditioning + gastrointestinal repair".

✦ Generated by Eureka AI based on patent content.

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Abstract

The hippophae rhamnoides fruit source nourishing paste is prepared from the following raw materials in parts by weight: 40 to 60 parts of fructus crataegi, 3 to 7 parts of hippophae rhamnoides fruit, 50 to 70 parts of white hyacinth bean, 140 to 160 parts of semen coicis, 25 to 35 parts of rhizoma dioscoreae, 50 to 70 parts of endothelium corneum gigeriae galli, 90 to 110 parts of poria cocos, 25 to 35 parts of fructus amomi, 50 to 70 parts of malt, 50 to 70 parts of fructus ziziphi jujubae, 50 to 70 parts of pericarpium citri reticulatae and 40 to 60 parts of isomaltooligosacharide. According to the sea-buckthorn source nourishing paste, sea-buckthorn and poria cocos are used as monarch drugs together to achieve the effects of tonifying spleen, eliminating dampness and repairing stomach and viscera together; the coix seeds, the white hyacinth beans and the Chinese yams are used as ministerial drugs and cooperate with one another, so that the spleen-tonifying and dampness-eliminating effects of the monarch drugs are enhanced, and both qi and yin are nourished; hawthorn, endothelium corneum gigeriae galli, malt, fructus amomi and pericarpium citri reticulatae are used as conductant drugs and emphasize on promoting digestion and removing food stagnation, promoting the circulation of qi and removing dampness, and food retention and qi stagnation associated with spleen deficiency are solved; the Chinese dates and the isomaltooligosacharide are used for regulating medicine properties and protecting intestinal microecology; the effects of nourishing the spleen and the stomach are achieved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine, and in particular to a sea-buckthorn nourishing paste for tonifying the spleen and stomach and a preparation method thereof. BACKGROUND

[0002] Spleen and stomach dysfunction (such as spleen deficiency, stomach yin deficiency, etc.) is a common problem in traditional Chinese medicine clinical practice, which is often manifested as loss of appetite, indigestion, stomach pain, acid reflux, and mucosal damage. Modern lifestyle (such as improper diet, excessive stress) and Helicobacter pylori infection and other factors further exacerbate the incidence of spleen and stomach diseases. Traditional Chinese medicine has unique advantages in regulating the spleen and stomach, and many classic prescriptions (such as Sijunzi Decoction and Shenling Baizhu Powder) play a role through multi-target and overall regulation, but some prescriptions are complex or have a slow effect. For example, the traditional Chinese medicine formula disclosed in Example 1 of the invention patent: a spleen and stomach nourishing Suolai tea and a preparation method thereof (202010981226X, publication date: 202010981226.X) has too many components, and is made into tea for drinking, which has insufficient effect on tonifying the spleen and stomach in a short period of time. Therefore, it is of great research value to develop a traditional Chinese medicine compound with simple formula and clear efficacy. SUMMARY

[0003] The present application aims to overcome the deficiencies of the prior art and provide a sea-buckthorn nourishing paste for tonifying the spleen and stomach and a preparation method thereof to solve the problems raised in the technical background.

[0004] To achieve the above-mentioned purpose, the present application realizes the following technical solutions:

[0005] In a first aspect, the present application provides a sea-buckthorn nourishing paste for tonifying the spleen and stomach, which is composed of the following raw materials in parts by weight: hawthorn 40-60 parts, sea-buckthorn 3-7 parts, white kidney bean 50-70 parts, yam 25-35 parts, chicken gizzard 50-70 parts, white ginseng 90-110 parts, sand 25-35 parts, wheat malt 50-70 parts, Chinese date 50-70 parts, dried tangerine or orange peel 50-70 parts, and low oligo-isomaltose 40-60 parts.

[0006] Preferably, the sea-buckthorn nourishing paste is composed of the following raw materials in parts by weight: hawthorn 50 parts, sea-buckthorn 5 parts, white kidney bean 60 parts, yam 30 parts, chicken gizzard 60 parts, white ginseng 100 parts, sand 30 parts, wheat malt 60 parts, Chinese date 60 parts, dried tangerine or orange peel 60 parts, and low oligo-isomaltose 50 parts.

[0007] Preferably, the sea-buckthorn nourishing paste has the effect of tonifying the spleen and stomach.

[0008] In a first aspect, the present application provides a preparation method of a sea-buckthorn nourishing paste for tonifying the spleen and stomach, which comprises the following steps:

[0009] S1, according to the prescription ingredients;

[0010] S2, take hawthorn, sea buckthorn, white beans, yam, chicken gizzard, hoelen, sand, wheat, jujube, dried tangerine peel, soak after adding water and decoct three times, combined filtrate (ensure that the filtrate is impurity) obtained traditional Chinese medicine extract;

[0011] S3, take traditional Chinese medicine extract into the pot, add oligoisomaltose, mix well and collect the paste, when the paste being heated is in the state of "honeycomb" boiling, start to complete the collection of paste. One is to grasp the firewood, too late, too early, the second is to grasp the opportunity of collecting paste, in that half a minute to one minute, can "drop water into a pearl" and "hang flag". After the completion of the collection of paste, hot packaging, after cooling, sealed, sea buckthorn source paste. The concentration of crude drug of sea buckthorn source paste is 0.5-0.6g / g, that is, each g paste contains 0.5-0.6g of crude drug (oligoisomaltose is not included in the crude drug measurement).

[0012] Preferably, in step S2, the first time according to the amount of medicinal material 8-10 times water, soak 30-40 minutes after the first time, decoct 1.5-3h.

[0013] Preferably, in step S2, the second and third times, according to the amount of medicinal material 6-8 times water, decoct 1-2h.

[0014] Preferably, the whole process of collecting paste is constantly stirred, skimming off the scum, and preventing the pot from sticking.

[0015] Analysis of sea buckthorn source paste:

[0016] Yi-rye, hoelen, hawthorn, white beans, yam, chicken gizzard, sand, wheat, dried tangerine peel, jujube, oligoisomaltose

[0017] I. Prescription composition and compatibility of monarch, minister, assistant and envoy

[0018] 1. Monarch: sea buckthorn, hoelen

[0019] Sea buckthorn: warm, return to spleen, stomach and lung, known as "life fruit", containing flavonoids, phospholipids and other ingredients, can invigorate the spleen and nourish the stomach, increase gastric mucosal secretion, reduce helicobacter pylori, relieve gastric ulcer and chronic gastrointestinal inflammation.

[0020] Hoelen: sweet and bland, return to heart, spleen and kidney, benefit water and remove dampness, invigorate the spleen and calm the heart, mainly remove the middle dampness and repair the abdominal distension and diarrhea caused by spleen deficiency and dampness.

[0021] Both of them are monarchs, and can invigorate the spleen and remove dampness, repair the stomach.

[0022] 2. Minister: Yi-rye, white beans, yam

[0023] Coix seed: sweet and cold, it returns to the spleen, stomach and lung channels, and can invigorate the spleen to stop diarrhea, drain water and eliminate dampness, and assist in strengthening the dampness-eliminating effect of Poria cocos. It also has the functions of pus-eliminating and detoxifying, and can improve diarrhea caused by spleen deficiency and dampness accumulation.

[0024] White fenugreek: sweet and warm, it returns to the spleen and stomach channels, and can invigorate the spleen to eliminate dampness, harmonize the center and relieve summer-heat, and is suitable for treating spleen deficiency, poor appetite, summer-heat and diarrhea.

[0025] Chinese yam: sweet and flat, it returns to the spleen, lung and kidney channels, and can invigorate the spleen and nourish the stomach, produce fluid and benefit the lung, and protect the spleen and stomach from dampness and yin damage.

[0026] The three herbs work together to strengthen the effect of the main herb in invigorating the spleen and eliminating dampness, and provide both qi and yin.

[0027] 3. Auxiliary herbs: hawthorn, chicken gizzard, malt, amomum villosum and dried orange peel

[0028] Digestive group (hawthorn, chicken gizzard and malt):

[0029] Hawthorn is sour and warm, and can resolve food accumulation and eliminate stagnation, and is especially good at eliminating oily food accumulation and removing blood stasis;

[0030] Chicken gizzard is sweet and flat, and can invigorate the stomach and resolve stubborn food accumulation;

[0031] Malt is sweet and flat, and can resolve rice and flour accumulation and soothe the liver and stomach.

[0032] Qi-regulating group (amomum villosum and dried orange peel):

[0033] Amomum villosum is pungent and warm, and can eliminate dampness, invigorate the spleen, warm the center and stop diarrhea, and relieve abdominal distension;

[0034] Dried orange peel is bitter and pungent and warm, and can dry dampness, resolve phlegm, regulate qi and harmonize the center, and assist in the ascending and descending of the spleen and stomach.

[0035] This group focuses on resolving food accumulation and eliminating dampness, and solving food accumulation and qi stagnation caused by spleen deficiency.

[0036] 4. Auxiliary herbs: Chinese date and low molecular weight isomaltooligosaccharide

[0037] Chinese date is sweet and warm, and returns to the spleen and stomach channels, and can tonify the center, benefit qi, nourish blood and calm the mind, and harmonize various herbs and moderate the harshness of other herbs.

[0038] Low molecular weight isomaltooligosaccharide is a modern prebiotic ingredient, and can promote the proliferation of beneficial bacteria in the intestines and improve digestive function, which is consistent with the concept of invigorating the spleen and assisting transportation in traditional Chinese medicine.

[0039] Both of them can harmonize the nature of the herbs and protect the intestinal microecology.

[0040] II. Core effects and action mechanisms

[0041] 1. Invigorate the spleen and eliminate dampness to restore transportation

[0042] Poria cocos, yiyi, white beans, water, sand, dried tangerine peel, and common wet and turbid; yam, jujube, spleen and qi, restore the spleen to clear and turbidity, and stop the generation of moisture from the root.

[0043] 2. Digestion and retention, smooth qi movement

[0044] Hawthorn, chicken gizzard, malt digestion, sand, dried tangerine peel, regulating qi and expanding the middle, solving the food less distension, acid regurgitation and acid regurgitation caused by spleen deficiency, breaking the vicious cycle of “food accumulation → spleen deficiency → dampness obstruction”.

[0045] 3. Nourishing stomach and promoting saliva, repairing mucosa

[0046] Sea buckthorn is rich in vitamins and unsaturated fatty acids, which can promote the repair of gastric mucosa; yam nourishes yin and promotes saliva, preventing dryness and damaging yin; low oligomaltose improves intestinal barrier and reduces inflammation.

[0047] 4. Bidirectional regulation, tonifying and supplementing

[0048] The whole party takes into account “pass” (digestion, qi movement, dampness) and “supplement” (spleen, qi, yin), which is suitable for spleen deficiency with dampness, and virtual and actual intermingling, avoiding pure supplement stagnation or simple attack and invasion.

[0049] Three, suitable population and typical symptoms

[0050] Spleen deficiency and dampness type of indigestion: loss of appetite, abdominal distension, loose stool or sticky and unsmooth.

[0051] Chronic gastrointestinal dysfunction: gastric acid reflux, belching, intestinal rumbling, or alternating constipation and diarrhea.

[0052] Post-illness or sub-health state: pale face, fatigue, and pale tongue with white and greasy fur.

[0053] Four, use attention

[0054] Wet and hot internal accumulation or real heat should be used with caution: there are more warm drugs in the formula (such as sand, dried tangerine peel), and the heat should be adjusted if the heat is obvious (red tongue, yellow fur, and bitter mouth). Add plantain, honeysuckle, etc.

[0055] Ointment taking method: take with warm water before meal, 1-2 times a day, supplemented by light diet, and avoid cold and greasy food.

[0056] This party combines traditional spleen and dampness drugs with modern prebiotics, reflecting the TCM concept of “spleen and stomach as the basis of postnatal life”, and restoring the function of the middle jiao through multiple target points.

[0057] Compared with the prior art, the beneficial effects of the present application are:

[0058] 1. The seabuckthorn nourishing paste of the present invention uses seabuckthorn and Poria as the main medicines, which can strengthen the spleen and eliminate dampness, and repair the stomach and intestines; coix seed, white hyacinth bean, and Chinese yam are the auxiliary medicines, and the three medicines work together to strengthen the effect of the main medicine in strengthening the spleen and eliminating dampness, while taking into account the dual nourishment of qi and yin; hawthorn, chicken gizzard lining, malt, amomum villosum, and tangerine peel are the guiding medicines, focusing on digestion, relieving stagnation, promoting qi and eliminating dampness, and solving the problems of food accumulation and qi stagnation associated with spleen deficiency; jujube and oligosaccharide harmonize the medicinal properties and protect the intestinal microecology.

[0059] 2. The seabuckthorn nourishing paste of the present invention contains coix seed, poria, white lentil, seabuckthorn, yam, tangerine peel and isomaltooligosaccharide, which work synergistically and have a significant effect on regulating the spleen and stomach.

[0060] 3. Adding isomaltooligosaccharide as a prebiotic forms a dual mechanism of "microecological conditioning + gastrointestinal repair" with traditional spleen-strengthening Chinese medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] Figure 1 This is a product picture of the seabuckthorn nourishing paste obtained in Example 1 of the present invention;

[0062] Figure 2 This is a bar graph showing the effects of each group of paste prescriptions on gastric mucosal damage in rats with spleen deficiency. DETAILED DESCRIPTION

[0063] The following describes the embodiments of the present invention through specific examples. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments. The details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that the following embodiments and features in the embodiments can be combined with each other unless they conflict.

[0064] Example 1

[0065] A seabuckthorn nourishing paste for regulating the spleen and stomach is composed of the following raw materials in parts by weight: 50 parts of hawthorn, 5 parts of seabuckthorn, 60 parts of white hyacinth bean, 150 parts of coix seed, 30 parts of yam, 60 parts of chicken gizzard lining, 100 parts of poria, 30 parts of amomum villosum, 60 parts of malt, 60 parts of jujube, 60 parts of tangerine peel, and 50 parts of isomaltooligosaccharide.

[0066] A method for preparing a seabuckthorn nourishing paste for nourishing the spleen and stomach comprises the following steps:

[0067] S1. Prepare ingredients according to the recipe;

[0068] S2, take hawthorn, sea buckthorn, white beans, coix seed, yam, gizzard, tuckahoe, sand ginger, malt, jujube, dried tangerine or orange peel, soak in water and then decoct three times, the first time, add water to 10 times the amount of medicinal materials, soak for 30 minutes, then decoct for 2 hours, the second and third times, add water to 8 times the amount of medicinal materials, decoct for 1 hour. After each decoction, filter the filtrate, combine the filtrate to obtain the traditional Chinese medicine extract;

[0069] S3, pour the traditional Chinese medicine extract into a pot, add oligoisomaltose, mix and stir evenly, then collect the paste. Stir constantly during the whole process of collecting the paste, skim off the scum, and prevent the pot from sticking. First, control the fire, if it is too late, the paste will be hard, if it is too early, the paste will be thin; second, control the timing of collecting the paste, within half a minute to one minute, the paste can be "droplets" and "flag". After the collection of the paste is completed, hot packaging is performed, and after cooling, it is sealed to obtain the sea buckthorn nourishing paste; at this time, the crude drug concentration of the sea buckthorn nourishing paste is 0.56g / g; the product diagram of the sea buckthorn nourishing paste is shown in Figure 1 .

[0070] Example 2

[0071] A sea buckthorn nourishing paste for regulating and nourishing the spleen and stomach, which is composed of the following raw materials in parts by weight: hawthorn 60 parts, sea buckthorn 3 parts, white beans 70 parts, coix seed 140 parts, yam 35 parts, gizzard 50 parts, tuckahoe 110 parts, sand ginger 35 parts, malt 70 parts, jujube 50 parts, dried tangerine or orange peel 50 parts, and oligoisomaltose 60 parts.

[0072] Example 3

[0073] A sea buckthorn nourishing paste for regulating and nourishing the spleen and stomach, which is composed of the following raw materials in parts by weight: hawthorn 40 parts, sea buckthorn 7 parts, white beans 50 parts, coix seed 160 parts, yam 25 parts, gizzard 70 parts, tuckahoe 90 parts, sand ginger 25 parts, malt 50 parts, jujube 70 parts, dried tangerine or orange peel 70 parts, and oligoisomaltose 40 parts.

[0074] Comparative Example 1

[0075] This comparative example is similar to Example 1, except that sea buckthorn is removed.

[0076] Comparative Example 2

[0077] This comparative example is similar to Example 1, except that tuckahoe is removed.

[0078] Comparative Example 3

[0079] This comparative example is similar to Example 1, except that white beans are removed.

[0080] Comparative Example 4

[0081] This comparative example is similar to Example 1, except that coix seed is removed.

[0082] Comparative Example 5

[0083] This comparative example is similar to Example 1, except that the yam is removed.

[0084] Comparative Example 6

[0085] This comparative example is similar to Example 1, except that the tangerine or orange peel is removed.

[0086] Comparative Example 7

[0087] This comparative example is similar to Example 1, except that the isomaltooligosaccharide is removed.

[0088] Comparative Example 8

[0089] The formula of this comparative example refers to the Chinese medicine formula disclosed in Example 1 of the invention patent: A Spleen-Invigorating and Stomach-Nourishing Suohe Tea and a Preparation Method Thereof (202010981226X, publication date: December 1, 2020), which is as follows:

[0090] Perilla 50 parts, Raphanus 50 parts, Taizishen 30 parts, Yam 50 parts, Fuling 50 parts, Renshen 10 parts, Dangshen 30 parts, Xiangyangshen 10 parts, Lingzhi 10 parts, Huangqi 30 parts, Gouqi 30 parts, Shanzha 50 parts, Mai 50 parts, Shenqu 50 parts, Jinejin 30 parts, Gegen 30 parts, Dangui 10 parts, Xingren 10 parts, Baodou 30 parts, Yiyiren 30 parts, Sharen 30 parts, Roudoukou 30 parts, Dingxiang 10 parts, Xiangchen 30 parts, Foshou 30 parts, Shaguang 30 parts, Wumei 30 parts, Huoxiang 10 parts, Chenpi 30 parts, Gongyang 50 parts, Pugongying 30 parts, Juhe 30 parts, Meigui 10 parts, Juyc 50 parts, Baihe 30 parts, Longyanshi 10 parts, Ganjiang 30 parts, Gaoliangjiang 20 parts, Lianzi 30 parts, Qianshi 30 parts, Dazao 50 parts, Gancao 30 parts.

[0091] The preparation methods of Examples 2-3 and Comparative Examples 1-8 are similar to those of Example 1.

[0092] Experimental Example 1

[0093] SPF level male SD rats, 10 weeks old, body weight 330-360 g, purchased from Jiangsu Ailinfeng Biological Technology Co., Ltd., and subjected to experiments after being normally fed for 1 week

[0094] 65 rats were randomly divided into a blank group, a spleen deficiency model group, a no-drug group, a sea buckthorn nourishing source paste group (Examples 1 and Comparative Examples 1-8), and a positive group (bismuth potassium citrate), a total of 13 groups, 5 rats in each group. Except for the blank group, the remaining groups were established into long-term spleen deficiency models of rats.

[0095] Spleen deficiency model rats: Xiaochengqi Decoction 3 ml / (time·rat) was given by gavage, once every other day, and at the same time, the rats were fed once every other day for 24 weeks. Xiaochengqi Decoction was composed of Magnolia officinalis, Citrus aurantium and Rheum officinale (ratio 3:3:2). After decoction, the filtrate was rotary evaporated at 70°C. The concentrated liquid obtained was concentrated to contain 1.0 g of crude drug per milliliter. Bismuth potassium citrate tablets were used to prepare a drug solution with a concentration of 1.8 mg / mL using sterile water for injection.

[0096] The blank group rats were normally fed and given normal saline 3 ml / time by gavage once every other day for 24 weeks. The spleen deficiency model group rats were fed once every two days to simulate irregular eating and drinking, and were given Xiaochengqi Decoction 3 ml / time by gavage once every other day for 24 weeks. The no-drug group rats were fed in the same way as the spleen deficiency model group for the first 20 weeks, and then were normally fed without any drug for 24 weeks. The sea buckthorn nourishing paste group (Example 1 and Comparative Examples 1-8) was fed in the same way as the spleen deficiency model group for the first 20 weeks, and then was normally fed and given sea buckthorn nourishing paste 1.35 g / kg (3 ml) by gavage once a day for 4 weeks. The positive group was fed in the same way as the spleen deficiency model group for the first 20 weeks, and then was normally fed and given bismuth potassium citrate 13.5 mg / kg (3 ml) by gavage once a day for 4 weeks. All rats were sacrificed at the end of the 24-week experiment for sample collection.

[0097] The whole stomach was removed, washed with 4°C normal saline, and then flattened after the water was absorbed. The ulcer index of the rat gastric mucosa was evaluated by the Guth method. The length of each lesion (mm) was scored as follows: 1 point for damage ≤1 mm (including erosion points); 2 points for 1 mm<damage≤2 mm; 3 points for 2 mm<damage≤3 mm; 4 points for 3 mm<damage≤4 mm; 5 points for >4 mm; and double points for damage width >2 mm. The total score of the whole stomach was the ulcer index of the rat gastric mucosa.

[0098] The ulcer inhibition rate (%) = (spleen deficiency model group ulcer index-experimental group ulcer index) / model group ulcer index x 100%, and the experimental group included the no-drug group, the sea buckthorn nourishing paste group (Example 1 and Comparative Examples 1-8), and the positive group (bismuth potassium citrate). The statistical results are shown in Table 1 and Figure 2

[0099] Table 1 Group Ulcer index Ulcer inhibition rate (%) Blank group 0.0±0.0 / Spleen deficiency model group 19.8±2.9 / No drug group 14.0±2.2 29.29 Example 1 group 4.8±1.5 75.76 Comparative example 1 8.0±1.4 60.6 Comparative example 2 7.8±1.9 60.61 Comparative example 3 7.4±1.8 62.63 Comparative example 4 7.6±1.5 61.62 Comparative example 5 7.4±1.6 62.63 Comparative example 6 7.2±1.3 63.64 Comparative example 7 7.6±1.9 61.62 Comparative example 8 7.0±1.4 64.65 Positive group 4.2±1.2 78.78

[0100] Table 1 and Figure 2 ​It can be seen that compared with the spleen deficiency model group, the gastric mucosa ulcer index of the example and the positive group is significantly reduced, and the ulcer inhibition rate is significantly increased, indicating that the degree of gastric mucosa ulcer is lighter, and the example and the positive group are better than the no drug group. It is shown that the sea buckthorn nourishing paste of the present application can relieve the damage of gastric mucosa ulcer in spleen deficiency rats, and the curative effect is equivalent to that of bismuth potassium citrate. Compared with Comparative Examples 1-7, the gastric mucosa ulcer index of Example 1 is significantly reduced, and the ulcer inhibition rate is significantly increased, indicating that the sea buckthorn nourishing paste contains yiyiren, fuling, baizhoudou, sea buckthorn, shanyao, chenpi and isomaltooligosaccharide, which have a synergistic effect and a significant conditioning effect on the spleen and stomach. Among them, isomaltooligosaccharide is added as a prebiotic, and a "micro-ecological conditioning + gastrointestinal repair" double mechanism is formed with traditional spleen-tonifying Chinese medicine. Compared with Comparative Example 8, the gastric mucosa ulcer index of Example 1 is significantly reduced, and the ulcer inhibition rate is significantly increased, indicating that the sea buckthorn nourishing paste has simple components, but has a good conditioning effect on the spleen and stomach, and too many components cannot play a better role.

[0101] The above examples only express the specific embodiments of the present application, which are described in detail and in detail, but cannot be understood as limiting the protection scope of the present application. It should be noted that for ordinary skilled persons in the art, without departing from the concept of the present application, a number of modifications and improvements can be made, which are within the protection scope of the present application.

Claims

1. A seabuckthorn nourishing paste for nourishing the spleen and stomach, characterized in that: The invention is composed of the following raw materials by weight: 40-60 parts of hawthorn, 3-7 parts of sea buckthorn, 50-70 parts of white hyacinth bean, 140-160 parts of coix seed, 25-35 parts of yam, 50-70 parts of chicken gizzard lining, 90-110 parts of poria, 25-35 parts of amomum villosum, 50-70 parts of malt, 50-70 parts of jujube, 50-70 parts of tangerine peel and 40-60 parts of isomaltooligosaccharide.

2. The seabuckthorn nourishing paste for nourishing the spleen and stomach according to claim 1, characterized in that: The invention is composed of the following raw materials by weight: 50 parts of hawthorn, 5 parts of sea buckthorn, 60 parts of white hyacinth bean, 150 parts of coix seed, 30 parts of yam, 60 parts of chicken gizzard lining, 100 parts of poria, 30 parts of amomum villosum, 60 parts of malt, 60 parts of jujube, 60 parts of tangerine peel and 50 parts of isomaltooligosaccharide.

3. The seabuckthorn nourishing paste for nourishing the spleen and stomach according to claim 1, characterized in that: The seabuckthorn nourishing paste has the effect of regulating the spleen and stomach.

4. The method for preparing the seabuckthorn nourishing paste for nourishing the spleen and stomach according to claim 1, characterized in that: The following steps are involved: S1. Prepare ingredients according to the recipe; S2, take coix seed, Poria cocos, hawthorn, white hyacinth bean, Amomum villosum, sea buckthorn, chicken gizzard lining, malt, tangerine peel, jujube, and Chinese yam, soak them in water and boil them three times, and combine the filtrates to obtain a Chinese medicine extract; S3. Pour the Chinese medicine extract into the pot, add isomaltooligosaccharide, mix well and then make a paste. When the paste is boiling in a "honeycomb" shape, the paste is formed. Divide it into packages while it is hot, let it cool and seal it to get the sea buckthorn nourishing paste.

5. The preparation method according to claim 4, characterized in that In step S2, water is added at 8-10 times the amount of the medicinal materials for the first time, and the mixture is soaked for 30-40 minutes before being boiled for the first time for 1.5-3 hours.

6. The preparation method according to claim 4, characterized in that In step S2, during the second and third decoctions, water is added according to 6-8 times the amount of the medicinal materials, and the decoction is performed for 1-2 hours.

7. The preparation method according to claim 4, characterized in that The crude drug concentration of the seabuckthorn nourishing paste obtained in step S3 is 0.5-0.6 g / g.

8. The preparation method according to claim 4, characterized in that Stir constantly during the whole process of collecting the paste, skim off the foam and prevent the pot from sticking.

Citation Information

Patent Citations

  • Spleen-tonifying and stomach-nourishing Zifu tea and preparation method thereof

    CN112006137A