A concave scar repair dressing and a preparation method thereof

Abstract

The present application belongs to the technical field of medical dressings, and particularly relates to a concave scar repair dressing and a preparation method thereof. The concave scar repair dressing comprises, from outside to the wound surface, a hydrophilic fiber layer, a hydrophobic barrier layer and a bioactive layer. The hydrophobic barrier layer is partially combined with the surface of the hydrophilic fiber layer through physical embedding, and the bioactive layer is fixed on the outside of the hydrophobic barrier layer through chemical cross-linking. The hydrophilic fiber layer is composed of polyvinyl alcohol / hyaluronic acid composite fibers prepared by electrospinning. The three-layer structure of the dressing simulates the partial functional gradient of the skin, covers hydrophilic absorption, barrier protection and active repair, and is more in line with the physiological repair requirements. The present application realizes the interlayer combination through the two mechanisms of physical embedding and chemical cross-linking, significantly improves the integrity and durability of the dressing, and avoids delamination during use.