Portable paraffin tissue sectioning machine

Abstract

This invention belongs to the field of industrial automatic control system technology, specifically relating to a portable paraffin tissue sectioning machine. This invention provides a compact, portable, and mobile automatic paraffin tissue sectioning device to solve the problems of large size and limited functionality of existing equipment, and to integrate sectioning and subsequent processing steps. The invention includes a housing, characterized in that: a slide conveying mechanism is provided on one side of the housing; a slide supply mechanism is provided at the input end of the conveying mechanism; the output end of the conveying mechanism is connected to the input end of a stationary rotating mechanism that runs through the other side of the housing; a paraffin block fixing and sectioning mechanism is provided above the middle of the rotating mechanism; a rotating transmission mechanism is provided at the end of the rotating mechanism; and a feeding mechanism is provided between the rotating transmission mechanism and the rotating mechanism.

Description

Technical Field

[0001] This invention belongs to the field of industrial automatic control system technology, specifically relating to a portable paraffin tissue slicer. Background Technology

[0002] Paraffin sectioning is a crucial step in pathological examination. It typically involves preparing micron-sized sections from paraffin-embedded tissue samples using a microtome, then transferring them onto glass slides for subsequent staining and observation. Current paraffin sectioning procedures generally include multiple steps such as paraffin block trimming, sectioning, slide preparation, flattening, baking, and storage.

[0003] Currently, the above procedures are mostly performed manually. Operators typically need to first mount the paraffin block onto the slide preparation equipment for trimming, then slice the tissue, and transfer the sliced ​​tissue onto a glass slide. Subsequently, the tissue slices need to be flattened using a water bath or brush, and then heated to adhere the tissue slices to the surface of the glass slide. After completing these steps, operators may also need to manually affix labels and classify and store the glass slides.

[0004] Existing paraffin-embedded tissue sectioning equipment is mainly used to cut paraffin-embedded tissue samples into thin sections for subsequent pathological analysis. This type of equipment is usually benchtop in shape, with a large overall size and complex structure. It typically needs to be fixed in the laboratory or on a dedicated workbench, making it inconvenient to carry and move, and failing to meet the need for flexible use.

[0005] Meanwhile, existing paraffin sectioning equipment has a relatively limited function, mainly used only for sectioning paraffin tissues. Post-section processing, such as slide receiving, tissue flattening, baking and fixing, labeling, and storage, still requires manual labor or other independent equipment. There is a lack of effective coordination between these processes, resulting in a cumbersome workflow.

[0006] Therefore, there is an urgent need in the existing technology for a paraffin tissue sectioning device that is compact, portable, and mobile, and can integrate multiple processing functions, in order to improve the overall level of automation and ease of use. Summary of the Invention

[0007] The present invention addresses the above-mentioned problems by providing an automated paraffin tissue sectioning device that is compact, portable, and mobile, thereby solving the problems of large size and limited functionality of existing devices and integrating sectioning and subsequent processing procedures.

[0008] The present invention adopts the following technical solution: the present invention includes a housing, characterized in that: a glass slide conveying mechanism is provided on one side of the housing, a glass slide supply mechanism is provided at the input end of the conveying mechanism, the output end of the conveying mechanism is connected to the input end of a station rolling mechanism that runs through the other side of the housing, a paraffin block fixing and slicing mechanism is provided above the middle of the rolling mechanism, a rotating transmission mechanism is provided at the end of the rolling mechanism, a feeding mechanism is provided between the rotating transmission mechanism and the rolling mechanism, the rotating transmission mechanism includes a rotating conveyor belt, the rotating transmission mechanism can rotate the rotating conveyor belt to the feeding station and the baking and flattening station, the feeding station corresponds to the feeding mechanism and the labeling mechanism, and the baking and flattening station corresponds to the baking and flattening mechanism and the specimen flipping and storage mechanism; The rolling mechanism includes a rolling tray and a rolling screw that passes through one side of the housing. The rolling screw is connected to a rolling motor. A rolling nut that cooperates with the rolling screw is provided on one side of the bottom of the rolling tray. A rolling guide block is provided on the other side of the rolling tray, and the rolling guide block cooperates with the rolling guide rail on the inner wall of the housing. The paraffin block fixing and slicing mechanism includes a slicing assembly located above the rolling guide rail and corresponding to the rolling tray. A micro-motion assembly is positioned above the slicing assembly, and a fixing frame assembly is positioned above the micro-motion assembly. The fixing frame assembly includes a rectangular frame fixedly connected to the housing, and a stepper motor is mounted on the rectangular frame. The output shaft of the stepper motor is connected to vertical lead screws at the four corners of the rectangular frame via a bevel gear assembly and connecting rods. The micro-motion assembly is also a rectangular frame structure, with micro-motion nuts connected to the vertical lead screws located inside its four corners. Vertical rotating rods are positioned on both sides of the micro-motion assembly, and the lower ends of both rotating rods are connected to a cam located within the micro-motion assembly. The rotating rod is connected to a fixed frame via a fixed frame, and the upper end of the rotating rod is connected to a rotating handle at the top of the fixed frame. Rotating the rotating rod allows the cam to extend out of the micro-motion assembly and fix the paraffin block mold within the rectangular frame of the micro-motion assembly. The slicing assembly includes support frames located on both sides below the micro-motion assembly. A slicing guide groove is provided in the support frame, and a slicing guide block is provided in the slicing guide groove. A cutter is provided between the two slicing guide blocks. The surface of the cutter corresponds to the area within the rectangular frame of the micro-motion assembly and the fixed frame assembly. A slicing motor is provided on the support frame, and the slicing motor is connected to the slicing guide block through a connecting rod assembly. The connecting rod assembly converts the rotation of the slicing motor into the linear reciprocating motion of the slicing guide block.

[0009] In a preferred embodiment of the present invention, a connecting piece is provided on the slicing guide block, and the blade is fixed to the connecting piece by screws.

[0010] As another preferred embodiment of the present invention, the linkage assembly includes a first rod fixedly connected to the output shaft, an end of the first rod hinged to one end of a second rod, and the other end of the second rod hinged to the slice guide block.

[0011] As a third preferred embodiment of the present invention, the supply mechanism includes a hopper and a hopper cover. The hopper cover cooperates with the housing. A spring hopper is provided on one side of the hopper cover. A compression spring is provided at the top of the spring hopper. The compression spring is connected to a hopper pressure block. The hopper pressure block is connected to a pressure plate through a connector passing through the spring hopper. The pressure plate corresponds to the hopper. A bottom opening is provided at the bottom of the hopper. A discharge mechanism corresponding to the bottom opening is provided inside the housing. The discharge mechanism includes a discharge frame. A discharge motor is provided on the discharge frame. The discharge motor is connected to a discharge rubber roller through a belt roller assembly with a tension wheel. The discharge rubber roller is connected to the discharge frame through a pressing spring with upward thrust. The discharge rubber roller corresponds to the bottom opening. A discharge port is provided on the side of the bottom of the hopper. A first inclined surface is provided on the side of the bottom of the hopper opposite to the discharge port. The conveying mechanism includes a suction device corresponding to the discharge port. The suction device includes a suction motor. The suction motor is connected to an active side roller located outside the discharge port via a pulley assembly. The active side roller is located at the end of a swing arm, and the other end of the swing arm is hinged to a hinge pin on the housing. Correspondingly, another swing arm is located on the other side outside the discharge port, and a driven side roller is located on the other swing arm. The end of the other swing arm is also hinged to a hinge pin on the housing. Both swing arms are equipped with a return spring. The elastic force of the two return springs causes the active and driven side rollers to move in the clamping direction. The maximum distance between the edges of the active and driven side rollers is less than the length of the glass slide, and the distance between the centers of the active and driven side rollers is greater than the length of the glass slide. Two support guide rails are located on the side of the suction device, and a first feeding conveyor belt is located between the two support guide rails. Feeding blocks are located on the first feeding conveyor belt. The ends of the two support guide rails correspond to the starting ends of the rolling mechanism. A guide plate is located on the outer side of the two support guide rails.

[0012] As a fourth preferred embodiment of the present invention, the rotating transmission mechanism includes a rotating motor connected to a rotating block. A rotating transmission belt is arranged on the side of the rotating block. When the rotating transmission belt is close to and parallel to the rolling pallet, it is a material unloading station. The material unloading mechanism corresponds to the middle of the rotating transmission belt. The material unloading mechanism is a material unloading transmission belt fixed to the housing. A material unloading lever is arranged on the material unloading transmission belt, and the material unloading lever corresponds to the upper surface of the rolling pallet. The upper surface of the rotating transmission belt is lower than the upper surface of the rolling pallet, and a discharge ramp is provided at the edge of the rolling pallet. A labeling mechanism is located above the edge of the housing at the rotating conveyor belt unloading station. When the rotating conveyor belt rotates and approaches the paraffin block fixing and slicing mechanism, perpendicular to the rolling tray, it forms the baking and flattening station. Above the baking and flattening station is the baking and flattening mechanism. At the baking and flattening station, a specimen flipping and storage mechanism is located at the end of the rotating conveyor belt. This mechanism includes a flipping plate mechanism and a specimen clamping mechanism. The flipping plate mechanism includes a flipping plate body corresponding to the end of the rotating conveyor belt. The unit is equipped with a supporting hinge frame, and the bottom of the flip plate body is equipped with a flip plate electric push rod; the upright clamping mechanism includes a support plate, the bottom of the support plate is equipped with a support base, and a linear slider guide rail assembly and a gear rack assembly are arranged between the support base and the bottom surface of the support plate. The gear rack assembly is connected to the storage motor; the support plate is equipped with a clamping block assembly; the clamping block assembly includes a fixed clamping block arranged on the support plate at the end away from the housing, and a movable clamping block connected to a sliding groove on the support plate. The movable clamping block closest to the housing is the first clamping block. The housing is equipped with a fixed winch device corresponding to the support plate. A movable winch is provided at the end of the pallet away from the housing. The winding rope of the fixed winch is fixedly connected to the first clamping block. Connecting ropes of equal length are provided between the movable clamping blocks and between the movable clamping blocks and the fixed clamping block. The clamping rope on the movable winch passes through the fixed clamping block and the movable clamping block and is fixedly connected to the first clamping block. The clamping rope is relatively fixed to the movable clamping blocks other than the first clamping block by friction. The magnitude of the friction allows the clamping rope to drive the movable clamping blocks to move and initially straighten and fix the glass slide without resistance.

[0013] As a fifth preferred embodiment of the present invention, the specimen flipping storage mechanism further includes a specimen storage chamber inside the housing, the specimen storage chamber being provided with an inlet and outlet corresponding to the tray; and a storage chamber cover being provided above the specimen storage chamber.

[0014] As a sixth preferred embodiment of the present invention, the baking flattening mechanism includes a baking pressing drive mechanism disposed at the top of the housing and corresponding to the baking flattening station. A baking flattening frame is disposed at the lower end of the pressing drive mechanism. A baking flexible positioning block is disposed at both ends of the baking flattening frame corresponding to the rotating conveyor belt located at the baking flattening station. A buffer spring is disposed between the baking flexible positioning block and the baking flattening frame. Two parallel rotating rollers are disposed in the middle of the baking flattening frame. The two parallel rotating rollers are connected to a flattening motor. Soft bristles are disposed on the rotating rollers. The two rotating rollers rotate in opposite directions and the bristles roll towards the two ends of the rotating conveyor belt. A hot air nozzle connected to a hot air blower on the baking flattening frame is disposed between the two rotating rollers.

[0015] As a seventh preferred embodiment of the present invention, the labeling mechanism includes a label printer, a paper feed port for the label printer is provided on the housing, and the paper output port of the label printer corresponds to the upper surface of the rotating conveyor belt of the unloading station near the edge of the housing; a cutting mechanism is provided above the paper output port; the cutting mechanism includes a cutting pressing drive device, which is connected to a cutting frame, and a cutting limit frame is provided on the cutting frame via a cutting buffer spring, and a cutting blade is provided on the cutting limit frame located above the paper output port; the label printer is provided with a limit block that cooperates with the cutting limit frame, the limit block restricts the stroke of the cutting blade, after cutting is completed, the cutting blade is blocked by the limit block and no longer descends, the cutting frame continues to descend, a sticker pressing block is provided inside the cutting frame, and a sticker buffer spring is provided between the sticker pressing block and the cutting frame.

[0016] As an eighth preferred embodiment of the present invention, the position of the sticker pressing block is parallel to the baking flexible positioning block at one end of the baking flattening mechanism; when the paper is pasted, a baking flexible positioning block descends to press one end of the glass slide, and at the same time, the sticker pressing block presses the sticker and the glass slide.

[0017] As a ninth preferred embodiment of the present invention, a drawer is provided on the housing corresponding to the lower part of the paraffin block fixing and slicing mechanism.

[0018] Compared with the prior art, the present invention has the following beneficial effects: 1. This invention integrates multiple processes such as glass slide supply, conveying, paraffin slicing, flattening and baking, labeling and storage into the same housing, realizing continuous automatic connection between each station, significantly improving the overall automation level, while the structure is compact, which facilitates the miniaturization and portability of the equipment.

[0019] 2. By setting up a material hopper, discharge rubber roller and side roller clamping structure, the single-slide glass slide can be stably separated and transported, which can effectively avoid problems such as multiple slides stacking and jamming, and improve the stability of slide supply.

[0020] 3. By setting up a rotating tray and a lead screw drive structure, the glass slides can be moved and positioned precisely between different workstations.

[0021] 4. By setting up a multi-screw micro-motion component driven by a stepper motor, the paraffin block is fed in a micro-scale. Combined with the reciprocating cutting structure, the slice thickness is made uniform and controllable, thus improving the slice quality.

[0022] 5. By setting a cam clamping structure, the paraffin block mold can be quickly clamped and fixed, simplifying the clamping process and improving operating efficiency.

[0023] 6. By setting up a rotating transmission mechanism, the glass slides can be switched and transported between different workstations, reducing intermediate transfer structures and improving the overall structural compactness.

[0024] 7. By setting up a feeding pusher structure, the glass slides are stably transferred from the rolling tray to the rotating conveyor belt, avoiding the glass slides from shifting or flipping during the transfer process.

[0025] 8. By setting up a baking and flattening mechanism, the tissue sections are flattened and heated and fixed by the combined action of flexible pressing blocks, roller brushes and hot air, thereby improving the adhesion quality and uniformity of the sections.

[0026] 9. By setting up a labeling mechanism, the automatic printing, cutting, and pasting of labels can be achieved, improving labeling efficiency and consistency of the pasting position.

[0027] 10. By setting up a flipping mechanism and a hoist-driven clamping structure, the slides can be automatically flipped and vertically clamped for storage, thereby increasing storage density and preventing slides from colliding or falling apart.

[0028] 11. By setting up a drawer structure, waste generated during the trimming process can be collected, making it easy to clean and keeping the inside of the equipment clean. Attached Figure Description

[0029] Figure 1 This is a schematic diagram of the structure of the present invention.

[0030] Figure 2 yes Figure 1 AA sectional view.

[0031] Figure 3 yes Figure 1 BB cross-sectional view.

[0032] Figure 4 yes Figure 1 CC section view.

[0033] Figure 5 This is a schematic diagram of the structure of the rotating transmission mechanism of the present invention when it is located at the baking and flattening station.

[0034] Figure 6 yes Figure 5 DD sectional view.

[0035] Figure 7 yes Figure 5 EE sectional view.

[0036] Figure 8 yes Figure 6 A magnified view of a portion of the image.

[0037] Figure 9 yes Figure 5 FF sectional view.

[0038] Figure 10 This is a schematic diagram of the structure of the present invention, in which the rotating transmission mechanism is located at the unloading station and the upright clamping mechanism is located in the specimen storage chamber.

[0039] Figure 11 This is a schematic diagram of the paraffin block fixing and slicing mechanism.

[0040] Figure 12 This is a side sectional view of the paraffin block fixing and slicing mechanism.

[0041] Figure 13 This is a schematic diagram of the slice component.

[0042] Figures 14-17 This is a schematic diagram of the operation process of the flip-plate mechanism and the upright clamping mechanism.

[0043] In the attached diagram, 1 is the housing, 2 is the slide supply mechanism, 3 is the conveying mechanism, 4 is the rolling mechanism, 5 is the paraffin block fixing and slicing mechanism, 6 is the rotating transmission mechanism, 7 is the feeding mechanism, 8 is the baking and flattening mechanism, 9 is the labeling mechanism, 10 is the specimen flipping and storage mechanism, 11 is the specimen storage chamber, 12 is the hopper, 13 is the hopper cover, 14 is the spring chamber, 15 is the downward pressure spring, 16 is the hopper pressure block, 17 is the pressure plate, 18 is the bottom opening, 19 is the discharge port, 20 is the first inclined surface, 21 is the discharge mechanism, 22 is the discharge motor, 23 is the belt roller assembly, 24 is the discharge rubber roller, 25 is the clamping spring, and 26 is the suction device. 27 is the suction motor, 28 is the active side roller, 29 is the driven side roller, 30 is the swing arm, 31 is the support guide rail, 32 is the first feeding conveyor belt, 33 is the feeding block, 34 is the guide plate, 35 is the rolling tray, 36 is the rolling screw, 37 is the rolling motor, 38 is the rolling screw nut, 39 is the rolling guide block, 40 is the rolling guide rail, 41 is the fixed frame assembly, 42 is the stepper motor, 43 is the bevel gear assembly, 44 is the connecting rod, 45 is the vertical screw, 46 is the micro-motion assembly, 47 is the micro-motion rectangular frame, 48 is the micro-motion screw nut, 49 is the rotating rod, 50 is the cam, 51 is the rotating handle, and 52 is the slicing assembly. 53 is the support frame, 54 is the slicing guide groove, 55 is the slicing guide block, 56 is the cutter, 57 is the slicing motor, 58 is the connecting rod assembly, 59 is the connecting piece, 60 is the screw, 61 is the rotating motor, 62 is the rotating block, 63 is the rotating conveyor belt, 64 is the unloading conveyor belt, 65 is the unloading paddle, 66 is the unloading ramp, 67 is the baking pressure drive mechanism, 68 is the baking flattening frame, 69 is the baking flexible positioning pressure block, 70 is the rotating roller, 71 is the flattening motor, 72 is the hot air blower, 73 is the hot air nozzle, 74 is the label printer, 75 is the paper feeding port, 76 is the paper output port, 77 is the cutting mechanism, and 78 is the cutting pressure drive. 79 is a cutting frame, 80 is a cutting limit frame, 81 is a cutting blade, 82 is a limit stop, 83 is a sticker pressing block, 84 is a sticker buffer spring, 85 is a flipping mechanism, 86 is a flipping body, 87 is a support hinge, 88 is a flipping electric push rod, 89 is a vertical sheet clamping mechanism, 90 is a tray, 91 is a support base, 92 is a linear slider guide rail assembly, 93 is a gear and rack assembly, 94 is a storage motor, 95 is a fixed clamping block, 96 is a movable clamping block, 97 is a first clamping block, 98 is a fixed winch device, 99 is a movable winch device, 100 is a drawer, 101 is a glass slide body, and 102 is a paraffin mold. Detailed Implementation

[0044] like Figures 1-17As shown, the supply mechanism includes a hopper 12 and a hopper cover 13. The hopper 12 is located inside the housing 1 on one side and is used to vertically stack multiple glass slides. The hopper cover 13 is closable and connectable to the housing 1. A spring hopper 14 is provided on one side of the hopper cover 13, and a downward pressure spring 15 is provided inside the spring hopper 14. The lower end of the downward pressure spring 15 is connected to the pressure block of the hopper 12. The pressure block of the hopper 12 is connected to a pressure plate 17 through a connecting body. The pressure plate 17 is located above the hopper 12 and is in contact with the stacked surface of the glass slides, and is used to apply a downward pressing force to the glass slides.

[0045] The bottom of the hopper 12 has a bottom opening 18, which corresponds to the discharge mechanism 21. A discharge port 19 is located on one side of the bottom of the hopper 12, allowing only the bottommost glass slide to pass through. A first inclined surface 20 is located on the side of the bottom of the hopper 12 opposite to the discharge port 19. This inclined surface 20 creates a horizontal difference between the bottommost glass slide and the slides above it, thus preventing the discharge mechanism 21 from failing to discharge due to excessive static friction between the glass slides.

[0046] The housing 1 is provided with a discharge mechanism 21 corresponding to the bottom opening 18. The discharge mechanism 21 includes a discharge frame and a discharge motor 22. The discharge motor 22 drives the discharge rubber roller 24 to rotate through the belt roller assembly 23. The discharge rubber roller 24 is located at the bottom opening 18 and partially extends into the bottom of the hopper 12. The discharge rubber roller 24 is connected to the discharge frame through a tensioning spring 25, so that it always presses the bottom glass slide upward.

[0047] Through the above structure, the discharge rubber roller 24 forms frictional contact with the bottom glass slide during rotation, thereby pushing the bottom glass slide out from the discharge port 19 and outputting it through the discharge port 19, while the upper glass slide is lowered to fill the gap under the action of the pressure plate 17 and its own weight.

[0048] The conveying mechanism 3 includes a suction device 26, a support rail 31, a first conveying belt 32, and a guide plate 34.

[0049] The suction device 26 is located outside the discharge port 19 and includes a suction motor 27. The suction motor 27 drives the active side roller 28 to rotate through a pulley assembly. The active side roller 28 is located at the end of the swing arm 30, and the other end of the swing arm 30 is hinged to the hinge shaft on the housing 1. Another swing arm 30 is located on the other side of the discharge port 19, and a driven side roller 29 is located on the other swing arm 30. Both swing arms 30 are equipped with a return spring. The return spring causes the active side roller 28 and the driven side roller 29 to always move towards each other, thereby clamping the glass slide entering between the two rollers.

[0050] Two support rails 31 are located on the side of the suction device 26, supporting both ends of the glass slide. A first feeding conveyor belt 32 is arranged between the two support rails 31, and feeding blocks 33 are arranged on the first feeding conveyor belt 32. Guide plates 34 are arranged on the outer sides of the two support rails 31 to limit the lateral displacement of the glass slide. The side of the feeding block 33 that contacts the glass slide is arc-shaped to overcome the motion change of the feeding block 33 when it changes from horizontal to vertical movement at the edge of the conveyor belt, ensuring that the glass slide can be smoothly pushed to the correct position.

[0051] The ends of the two support rails 31 correspond to the starting end of the rolling mechanism 4, so that the glass slide can be smoothly transferred from the conveying mechanism 3 to the subsequent work station.

[0052] When in use, first place multiple glass slides vertically in the hopper 12 and close the hopper cover 13. The pressure plate 17 inside the hopper cover 13 applies continuous downward pressure to the glass slides under the action of the downward pressure spring 15, so that the glass slides are always tightly stacked.

[0053] Start the discharge motor 22, which drives the discharge rubber roller 24 to rotate. Under the action of the top spring 25, the discharge rubber roller 24 makes close contact with the bottom glass slide. Under the action of friction, the bottom glass slide is pushed out from the discharge port 19 and enters the suction device 26 area through the discharge port 19.

[0054] When the glass slide enters between the active side roller 28 and the driven side roller 29, the two side rollers clamp the glass slide under the action of the return spring. The suction motor 27 drives the active side roller 28 to rotate, thereby moving the glass slide forward and conveying the glass slide to the top of the support guide rail 31.

[0055] After the glass slide enters the two support rails 31, its two ends are supported by the support rails 31, and the guide plate 34 restricts its lateral movement. At the same time, the first feeding conveyor belt 32 moves under the drive, and the feeding block 33 contacts the edge of the glass slide and pushes the glass slide to move along the rail direction.

[0056] Finally, the glass slide moves to the end of the support rail 31 under the push of the feeding block 33, and smoothly enters the starting end of the rolling mechanism 4, falling onto the rolling tray 35.

[0057] The paraffin block fixing and slicing mechanism 5 is located above the rolling mechanism 4 and corresponds to the rolling tray 35, and is used to clamp and slice the paraffin block.

[0058] The paraffin block fixing and slicing mechanism 5 includes a fixing frame assembly 41, a micro-motion assembly 46, and a slicing assembly 52.

[0059] The fixed frame assembly 41 includes a rectangular frame fixedly connected to the housing 1. A stepper motor 42 is provided on the rectangular frame. The output shaft of the stepper motor 42 is connected to the vertical lead screws 45 located at the four corners of the rectangular frame through a bevel gear assembly 43 and a connecting rod 44. The vertical lead screws 45 are vertically arranged.

[0060] The micro-motion component 46 is located below the fixed frame component 41. The micro-motion component 46 has a rectangular frame structure, and micro-motion nuts 48 that cooperate with the vertical lead screw 45 are provided inside its four corners, so that the micro-motion component 46 can move vertically up and down under the drive of the stepper motor 42.

[0061] The micro-motion component 46 has vertical rotating rods 49 on both sides. The lower end of the rotating rod 49 is connected to the cam 50 inside the micro-motion component 46, and the upper end of the rotating rod 49 passes through the fixed frame and is connected to the rotating handle 51 on the top of the fixed frame. By rotating the rotating handle 51, the rotating rod 49 is driven to rotate, thereby causing the cam 50 to extend outward to clamp and fix the paraffin block mold located in the rectangular frame of the micro-motion component 46.

[0062] The slicing assembly 52 is located below the micro-motion assembly 46 and includes support frames 53 on both sides. A slicing guide groove 54 is provided in the support frame 53, and a slicing guide block 55 is provided in the slicing guide groove 54. A cutter 56 is provided between the two slicing guide blocks 55. The cutter 56 is located below the rectangular frame of the micro-motion assembly 46 and corresponds to the position of the paraffin block.

[0063] A slicing motor 57 is provided on the support frame 53. The slicing motor 57 is connected to the slicing guide block 55 through a connecting rod assembly 58. The connecting rod assembly 58 includes a first rod fixedly connected to the output shaft of the slicing motor 57. One end of the first rod is hinged to one end of a second rod, and the other end of the second rod is hinged to the slicing guide block 55, thereby converting the rotational motion of the slicing motor 57 into the linear reciprocating motion of the slicing guide block 55. A connecting piece 59 is provided on the slicing guide block 55, and the cutter 56 is fixed to the connecting piece 59 by screws 60.

[0064] In use, open the cover on the housing 1 above the paraffin block fixing and slicing mechanism 5, and then place the paraffin block mold into the rectangular frame of the micro-motion component 46 from above the equipment, so that the paraffin block is directly above the cutter 56. The width of the cutter 56 is set to about one-fifth of the width of the paraffin block mold. After use, the cutter 56 always returns to the center position of the rectangular frame of the micro-motion component 46; thus, the cutter 56 supports the paraffin block, so that the paraffin block can be cut immediately without the need to clamp the paraffin block mold and then adjust the height.

[0065] Then, rotate the rotating handle 51 on the top of the fixed frame, which drives the rotating rod 49 to rotate, causing the cam 50 to extend outward, thereby clamping and fixing the paraffin block mold to prevent displacement during the slicing process.

[0066] Start the slicing motor 57. The slicing motor 57 drives the slicing guide block 55 to reciprocate linearly along the slicing guide groove 54 through the connecting rod assembly 58, thereby driving the cutter 56 to reciprocate cutting in the horizontal direction to slice the paraffin block.

[0067] During the slicing process, the stepper motor 42 drives four vertical lead screws 45 to rotate synchronously, causing the micro-motion component 46 to move slightly downward in the vertical direction. After each reciprocating motion of the cutter 56, the micro-motion component 46 descends a predetermined small distance, which can be set by the control panel to advance 1 to 5 micrometers at a time, so that the paraffin block is fed step by step, thereby achieving continuous and uniform thin-film cutting.

[0068] In the initial stage, the paraffin block is trimmed by continuous reciprocating cutting, and the waste generated during the trimming process falls into the drawer 100 below. After trimming is completed, the rotating tray 35 transports the glass slide to the underside of the slide assembly 52, and the slide operation continues. The cut tissue slides fall onto the surface of the glass slide under the action of gravity, thus receiving the tissue slides.

[0069] Through the combination of the above structure and actions, stable clamping, micro-feeding, and high-precision slicing of paraffin blocks are achieved.

[0070] The rotating transmission mechanism 6 is located at the end of the rolling mechanism 4 and is used to receive the glass slides conveyed by the rolling tray 35 and transport the glass slides to the subsequent work station.

[0071] The rotation transmission mechanism 6 includes a rotation motor 61, a rotation block 62, and a rotation transmission belt 63. The rotation motor 61 is connected to the rotation block 62 and is used to drive the rotation block 62 to rotate around a preset axis. The rotation transmission belt 63 is located on the side of the rotation block 62 and rotates with the rotation block 62 as a whole.

[0072] The upper surface of the rotating conveyor belt 63 is used to support the glass slides, and the linear movement of the conveyor belt surface is achieved by independent driving.

[0073] The rotating conveyor belt 63 can switch between at least two positions: when the rotating conveyor belt 63 is close to and basically parallel to the rolling tray 35, it forms a feeding station; when the rotating conveyor belt 63 rotates to the side close to the paraffin block fixing and slicing mechanism 5 and forms an angle change with the rolling tray 35, it forms a baking and flattening station.

[0074] The rotating conveyor belt 63 and the rolling tray 35 are arranged adjacent to each other at the unloading station. An unloading mechanism 7 is provided between the end of the rolling tray 35 and the rotating conveyor belt 63. The unloading mechanism 7 includes an unloading conveyor belt 64 and an unloading paddle 65 disposed on the unloading conveyor belt 64. The unloading paddle 65 can move along the direction of the unloading conveyor belt 64 and contact the side of the glass slide on the upper surface of the rolling tray 35 to realize the lateral pushing of the glass slide.

[0075] After the sections are sliced, the rolling motor 37 drives the rolling screw 36 to rotate, thereby moving the rolling tray 35 along the rolling guide rail 40, so that the glass slide carrying the tissue sections gradually moves towards the end of the rolling mechanism 4.

[0076] At the same time, the rotating transmission mechanism 6 is pre-rotated to the unloading position under the drive of the rotating motor 61, so that the rotating transmission belt 63 is adjacent to and basically parallel to the rolling tray 35.

[0077] When the rotating pallet 35 moves to the end position, the feeding mechanism 7 is started, and the feeding conveyor belt 64 drives the feeding block 65 to move in a predetermined direction, so that the feeding block 65 contacts the edge of the glass slide on the rotating pallet 35 and pushes the glass slide from the surface of the rotating pallet 35 to the surface of the rotating conveyor belt 63.

[0078] During the pushing process, since the upper surface of the rotating conveyor belt 63 is lower than the upper surface of the rolling tray 35, the glass slide achieves a stable transition under the action of the unloading block 65 and the unloading ramp 66.

[0079] After the transfer is completed, the rotating tray 35 returns to its initial position, ready to receive the next glass slide; the rotating transmission mechanism 6 drives the rotating block 62 to rotate via the rotating motor 61 according to the needs of subsequent processes, so that the rotating transmission belt 63 switches to the baking and flattening station.

[0080] When the glass slide is conveyed onto the rotating conveyor belt 63 and moved to the predetermined position, the rotating motor 61 drives the rotating block 62 to rotate, so that the rotating conveyor belt 63 rotates from the unloading station to the baking and flattening station. At this time, the rotating conveyor belt 63 and the rolling tray 35 form an angle change and are located below the baking and flattening mechanism 8.

[0081] The baking flattening mechanism 8 is located on the top of the housing 1 and includes a baking pressing drive mechanism 67 and a baking flattening frame 68 connected thereto. The baking flattening frame 68 has baking flexible positioning blocks 69 at both ends, and the baking flexible positioning blocks 69 are connected to the baking flattening frame 68 through buffer springs. The baking flattening frame 68 has two parallel rotating rollers 70 in the middle, which are driven to rotate by a flattening motor 71. The surface of the rotating rollers 70 is covered with soft bristles. A hot air nozzle 73 connected to a hot air blower 72 is provided between the two rotating rollers 70.

[0082] When the rotating conveyor belt 63 reaches the baking and flattening station, the baking pressing drive mechanism 67 is activated, which drives the baking flattening frame 68 to move downward, so that the baking flexible positioning blocks 69 on both sides contact the two ends of the glass slide and flexibly press and position the glass slide.

[0083] Subsequently, the rotating roller 70 rotates in the opposite direction under the drive of the flattening motor 71. The soft bristles on the rotating roller 70 brush and flatten the paraffin tissue sections on the glass slide. At the same time, the hot air blower 72 blows hot air into the section area through the hot air nozzle 73 to soften the paraffin tissue appropriately.

[0084] Under the combined action of a soft-bristled roller and hot air, the paraffin tissue sections gradually flatten and adhere evenly to the surface of the glass slide. After the flattening process is complete, the flattening mechanism is lifted.

[0085] After the flattening and baking are completed, the rotating motor 61 drives the rotating block 62 to rotate again, so that the rotating conveyor belt 63 rotates to the labeling station, so that one end of the glass slide corresponds to the labeling mechanism 9.

[0086] At this time, the baking and flattening mechanism 8 operates again, causing one of the baking flexible positioning blocks 69 on one side to press down on one end of the glass slide to fix the glass slide locally and provide stable support for subsequent labeling.

[0087] The labeling mechanism 9 includes a label printer 74, a cutting mechanism 77, and a sticker pressing structure.

[0088] During the labeling process, the label printer 74 outputs a label, which is output from the paper outlet 76 to the corresponding position above the glass slide; then the cutting and pressing drive 78 is activated, which drives the cutting frame 79 to move downward as a whole, and the cutting blade 81 on the cutting frame 79 cuts the label.

[0089] During the cutting process, the cutting blade 81 stops descending after contacting the limiting block 82, while the cutting frame 79 continues to move downward. The sticker pressing block 83, which is set in the cutting frame 79, presses the label under the action of the sticker buffer spring 84, so that the label is attached to one end of the glass slide.

[0090] During the labeling process, the baking flexible positioning block 69 and the sticker pressing block 83 cooperate to keep the glass slide stable, thereby improving the accuracy and firmness of the label application.

[0091] After labeling is completed, the rotating motor 61 drives the rotating conveyor belt 63 to enter the baking and flattening station. The rotating conveyor belt 63 rotates itself, transporting the glass slide to the specimen flipping and storage mechanism 10 at the end of the rotating conveyor belt 63.

[0092] The specimen flipping and storage mechanism 10 includes a flipping mechanism 85 and a specimen clamping mechanism 89. The flipping mechanism 85 includes a flipping body 86, a support hinge 87, and a flipping electric push rod 88.

[0093] When the slide moves to the position of the flip plate body 86, the flip plate electric push rod 88 is activated, which drives the flip plate body 86 to rotate around the support hinge 87, causing the flip plate body 86 to tilt, thereby allowing the slide to slide along the surface of the flip plate body 86 and enter the area of ​​the support plate 90.

[0094] After the slide enters the area of ​​the tray 90, the slide clamping mechanism 89 activates, and the moving winch 99 drives the clamping rope to tighten. The clamping rope drives each movable clamp 96 to move towards the fixed clamp 95, thereby gradually reducing the gap between the first movable clamp 96 and the fixed clamp 95. After the first movable clamp 96 contacts the slide, it stops moving. The clamping rope overcomes friction and begins to drag the remaining movable clamps 96 (excluding the first one) along. Under the action of the gear and rack, the tray 90 moves forward one position, aligning the gap between the flip plate body 86 and the first and second movable clamps 96, preparing for the upright storage of the second slide.

[0095] By repeating the above actions, the tray 90 gradually moves forward, carrying the upright glass slides into the specimen storage chamber 11. When the tray 90 is full, the moving winch device 99 drives the first clamp 97 to tighten, securing all the glass slides. This allows the entire invention to be carried without the glass slides containing the specimens becoming loose.

[0096] When release is required, the fixed winch device 98 is activated to restore the spacing between the clamps, thus facilitating the next specimen storage.

[0097] Finally, the slides are stored upright in an orderly manner in the specimen storage chamber 11 and sealed and protected by the storage chamber cover 13.

[0098] It is understood that the above specific description of the present invention is only for illustrating the present invention and is not limited to the technical solutions described in the embodiments of the present invention. Those skilled in the art should understand that modifications or equivalent substitutions can still be made to the present invention to achieve the same technical effect; as long as the use needs are met, they are all within the protection scope of the present invention.

Claims

1. A portable paraffin tissue microtome, comprising a housing (1), characterized in that: A slide conveying mechanism (3) is provided on one side of the housing (1). A slide supply mechanism is provided at the input end of the conveying mechanism (3). The output end of the conveying mechanism (3) is connected to the input end of the station rolling mechanism (4) that runs through the other side of the housing (1). A paraffin block fixing and slicing mechanism (5) is provided above the middle of the rolling mechanism (4). A rotating transmission mechanism (6) is provided at the end of the rolling mechanism (4). A feeding mechanism (7) is provided between the rotating transmission mechanism (6) and the rolling mechanism (4). The rotating transmission mechanism (6) includes a rotating transmission belt (63). The rotating transmission mechanism (6) can rotate the rotating transmission belt (63) to the feeding station and the baking and flattening station. The feeding station corresponds to the feeding mechanism (7) and the labeling mechanism (9). The baking and flattening station corresponds to the baking and flattening mechanism (8) and the specimen flipping and storage mechanism (10). The rolling mechanism (4) includes a rolling tray (35) and a rolling screw (36) that passes through one side of the housing (1). The rolling screw (36) is connected to the rolling motor (37). A rolling nut (38) that cooperates with the rolling screw (36) is provided on one side of the bottom of the rolling tray (35). A rolling guide block (39) is provided on the other side of the rolling tray (35). The rolling guide block (39) cooperates with the rolling guide rail (40) on the inner wall of the housing (1). The paraffin block fixing and slicing mechanism (5) includes a slicing component (52) located above the rolling guide rail (40) and corresponding to the rolling tray (35). A micro-motion component (46) is provided above the slicing component (52), and a fixed frame component (41) is provided above the micro-motion component (46). The fixed frame component (41) includes a rectangular frame fixedly connected to the housing (1). A stepper motor (42) is provided on the rectangular frame. The output shaft of the stepper motor (42) is connected to the vertical lead screws (45) at the four corners of the rectangular frame through a bevel gear assembly (43) and a connecting rod (44). The micro-motion component (46) is also a rectangular frame structure. Micro-motion nuts (48) connected to the vertical lead screws (45) are provided inside the four corners of the micro-motion component (46). Vertical rotating rods (49) are provided on both sides of the micro-motion component (46). The lower ends of the two rotating rods (49) are connected to a cam (50) located inside the micro-motion component (46). (49) The upper end passes through a fixed frame and is connected to the rotating handle (51) at the top of the fixed frame; by rotating the rotating rod (49), the cam (50) can extend out of the micro-motion component (46) and fix the paraffin block mold in the rectangular frame of the micro-motion component (46); the slicing component (52) includes a support frame (53) located on both sides below the micro-motion component (46), a slicing guide groove (54) is provided in the support frame (53), a slicing guide block (55) is provided in the slicing guide groove (54), and a cutter (56) is provided between the two slicing guide blocks (55); the surface of the cutter (56) corresponds to the area in the rectangular frame of the micro-motion component (46) and the fixed frame component (41); a slicing motor (57) is provided on the support frame (53), and the slicing motor (57) is connected to the slicing guide block (55) through a connecting rod assembly (58); the connecting rod assembly (58) converts the rotation of the slicing motor (57) into the linear reciprocating motion of the slicing guide block (55).

2. The portable paraffin tissue sectioner according to claim 1, characterized in that: The slicing guide block (55) is provided with a connecting piece (59), and the blade is fixed to the connecting piece (59) by screws (60).

3. A portable paraffin tissue sectioner according to claim 1, characterized in that: The connecting rod assembly (58) includes a first rod fixedly connected to the output shaft, one end of the first rod being hinged to one end of a second rod, and the other end of the second rod being hinged to the slice guide block (55).

4. A portable paraffin tissue sectioner according to claim 1, characterized in that: The supply mechanism includes a hopper (12) and a hopper cover (13). The hopper cover (13) is fitted with the housing (1). A spring hopper (14) is provided on one side of the hopper cover (13). A compression spring (15) is provided at the top inside the spring hopper (14). The compression spring (15) is connected to a hopper (12) pressure block. The hopper (12) pressure block is connected to a pressure plate (17) through a connector passing through the spring hopper (14). The pressure plate (17) corresponds to the hopper (12). A bottom opening (18) is provided at the bottom of the hopper (12). A discharge mechanism (21) corresponding to the bottom opening (18) is provided inside the housing (1). The system includes a discharge frame, on which a discharge motor (22) is mounted. The discharge motor (22) is connected to a discharge rubber roller (24) via a belt roller assembly (23) with a tension wheel. The discharge rubber roller (24) is connected to the discharge frame via a tensioning spring (25) that pushes upward. The discharge rubber roller (24) corresponds to the bottom opening (18). A discharge port (19) is provided on the bottom side of the hopper (12), and a first inclined surface (20) is provided on the bottom side of the hopper (12) opposite to the discharge port (19). The conveying mechanism (3) includes a suction device (26) corresponding to the discharge port (19). The device includes a suction motor (27), which is connected to an active side roller (28) located outside the discharge port (19) via a pulley assembly. The active side roller (28) is located at the end of a swing arm (30), and the other end of the swing arm (30) is hinged to a hinge pin on the housing (1). Correspondingly, another swing arm (30) is located on the other side outside the discharge port (19), and a driven side roller (29) is located on the other swing arm (30). The end of the other swing arm (30) is also hinged to a hinge pin on the housing (1). A return spring is provided on both swing arms (30), and the elastic force of the two return springs causes the active side roller (28) and the driven side roller (29) to move together. 29) Move in the clamping direction, the limit distance between the edges of the active side roller (28) and the driven side roller (29) is less than the length of the glass slide, and the distance between the centers of the active side roller (28) and the driven side roller (29) is greater than the length of the glass slide; two support rails (31) are provided on the side of the suction device (26), a first feeding conveyor belt (32) is provided between the two support rails (31), and feeding blocks (33) are provided on the first feeding conveyor belt (32); the ends of the two support rails (31) correspond to the starting end of the rolling mechanism (4); a guide plate (34) is provided on the outside of the two support rails (31).

5. A portable paraffin tissue sectioner according to claim 1, characterized in that: The rotating transmission mechanism (6) includes a rotating motor (61), which is connected to a rotating block (62). A rotating transmission belt (63) is provided on the side of the rotating block (62). When the rotating transmission belt (63) is close to and parallel to the rolling pallet (35), it is a material unloading station. The unloading mechanism (7) corresponds to the middle of the rotating transmission belt (63). The unloading mechanism (7) is a material unloading transmission belt (64) fixed to the housing (1). A material unloading paddle (65) is provided on the material unloading transmission belt (64), which corresponds to the upper surface of the rolling pallet (35). The height of the upper surface of the rotating transmission belt (63) is lower than the height of the upper surface of the rolling pallet (35). The edge of the rolling pallet (35) is provided with a material unloading point. A ramp (66); a labeling mechanism (9) is provided above the side of the shell (1) near the unloading station of the rotating conveyor belt (63); when the rotating conveyor belt (63) rotates and is close to the side of the paraffin block fixing and slicing mechanism (5) and perpendicular to the rolling tray (35), it is a baking and flattening station; when the rotating conveyor belt (63) is above the baking and flattening station, it is a baking and flattening mechanism (8); when the rotating conveyor belt (63) is at the baking and flattening station, a specimen flipping and storage mechanism (10) is provided at the end of the rotating conveyor belt (63); the specimen flipping and storage mechanism (10) includes a flipping mechanism (85) and a specimen clamping mechanism (89); the flipping mechanism (85) includes a flipping plate corresponding to the end of the rotating conveyor belt (63). The body (86) has a supporting hinge (87) at one end and a flip-plate electric push rod (88) at the bottom. The upright clamping mechanism (89) includes a tray (90), a support base (91) at the bottom of the tray (90), a linear slider guide rail assembly (92) and a gear rack assembly (93) between the support base (91) and the bottom surface of the tray (90), and the gear rack assembly (93) is connected to the storage motor (94). The tray (90) has a clamping block assembly. The clamping block assembly includes a fixed clamping block (95) on the tray (90) away from the housing (1) and a movable clamping block (96) connected to the sliding groove on the tray (90). The clamping block is closest to the housing (1). 1) The movable clamping block (96) is the first clamping block (97). The housing (1) is provided with a fixed winch device (98) corresponding to the pallet (90). The pallet (90) is provided with a movable winch device (99) at the end away from the housing (1). The winding rope of the fixed winch device (98) is fixedly connected to the first clamping block (97). Connecting ropes of equal length are provided between the movable clamping blocks (96) and between the movable clamping block (96) and the fixed clamping block (95). The clamping winding rope on the movable winch device (99) passes through the fixed clamping block (95) and the movable clamping block (96) and is fixedly connected to the first clamping block (97). The clamping winding rope is relatively fixed to the movable clamping blocks (96) other than the first clamping block (97) by friction.The magnitude of the frictional force allows the clamping rope to move the movable clamp (96) without resistance, thus initially uprighting and fixing the glass slide.

6. A portable paraffin tissue sectioner according to claim 1, characterized in that: The specimen flipping storage mechanism (10) also includes a specimen storage chamber (11) inside the shell (1), the specimen storage chamber (11) is provided with an inlet and outlet corresponding to the tray (90); a storage chamber cover (13) is provided above the specimen storage chamber (11).

7. A portable paraffin tissue sectioner according to claim 1, characterized in that: The baking flattening mechanism (8) includes a baking pressing drive mechanism (67) located at the top of the housing (1) and corresponding to the baking flattening station. A baking flattening frame (68) is provided at the lower end of the pressing drive mechanism. A baking flexible positioning block (69) is provided at both ends of the baking flattening frame (68) corresponding to the rotating conveyor belt (63) located at the baking flattening station. A buffer spring is provided between the baking flexible positioning block (69) and the baking flattening frame (68). Two parallel rotating rollers (70) are provided in the middle of the baking flattening frame (68). The two parallel rotating rollers (70) are connected to a flattening motor (71). Soft bristles are provided on the rotating rollers (70). The two rotating rollers (70) rotate in opposite directions and make the bristles roll towards the two ends of the rotating conveyor belt (63). A hot air nozzle (73) connected to the hot air blower (72) on the baking flattening frame (68) is provided between the two rotating rollers (70).

8. A portable paraffin tissue sectioner according to claim 1, characterized in that: The labeling mechanism (9) includes a label printer (74), and a paper feed port (75) for the label printer (74) is provided on the housing (1). The paper output port (76) of the label printer (74) corresponds to the upper surface of the rotating conveyor belt (63) of the unloading station near the edge of the housing (1). A cutting mechanism (77) is provided above the paper output port (76). The cutting mechanism (77) includes a cutting pressure drive device (78), which is connected to a cutting frame (79). A cutting limit frame (80) is provided on the cutting frame (79) through a cutting buffer spring. The cutting limit frame (80) is provided with a cutting blade (81) located above the paper outlet (76); the label printer (74) is provided with a limit block (82) that cooperates with the cutting limit frame (80). The limit block (82) restricts the stroke of the cutting blade (81). After cutting, the cutting blade (81) is blocked by the limit block (82) and no longer descends. The cutting frame (79) continues to descend. The cutting frame (79) is provided with a sticker pressing block (83). A sticker buffer spring (84) is provided between the sticker pressing block (83) and the cutting frame (79).

9. A portable paraffin tissue sectioner according to claim 1, characterized in that: The sticker pressing block (83) is parallel to the baking flexible positioning block (69) at one end of the baking flattening mechanism (8); when the paper is pasted, a baking flexible positioning block (69) descends and presses one end of the glass slide, while the sticker pressing block (83) presses the sticker and the glass slide.

10. A portable paraffin tissue sectioner according to claim 1, characterized in that: A drawer (100) is provided on the housing (1) below the paraffin block fixing and slicing mechanism (5).

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