Device and method for directionally preparing high-abundance 13CO2 from 13CO through CuO catalytic oxidation

By designing a composite bed structure of CuO catalytic particles and quartz wool-quartz sand and an integrated device, the problems of catalytic selectivity and temperature control in catalytic oxidation were solved, and the preparation of high-purity, high-abundance 13CO2 was achieved, which is suitable for medical diagnosis, isotope tracing and high-end organic synthesis.

CN122273404APending Publication Date: 2026-06-26ANHUI ZHONGHE TONGYUAN TECH CO LTD
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Patent Information

Application Number
CN202610463581.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-09
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing technologies for preparing 13CO2 by catalytic oxidation suffer from problems such as insufficient selectivity of the catalytic system, inaccurate control of reaction temperature, poor sealing of the equipment, and complex product separation and purification. These problems result in low product purity, loss of isotope abundance, and complex operation, making it difficult to meet the needs of high-end applications.

Method used

By employing a CuO catalytic particle and quartz wool-quartz sand composite bed structure, combined with an integrated device design, and through high-purity nitrogen purging, low-temperature collection, and multi-stage partial pressure purification processes, the efficient and directional conversion and purification of 13CO to 13CO2 is achieved.

Benefits of technology

It significantly improves catalytic conversion efficiency and selectivity, with product purity reaching 99.5% and 13C abundance recovery rate ≥99%. It is easy to operate, meets the requirements of green chemical production, and is suitable for industrial scale-up.

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Abstract

The invention provides a device and a method for directionally preparing high-abundance 13CO2 from 13CO through CuO catalytic oxidation, and belongs to the technical field of preparation of stable isotope labeled compounds. The device is an integrated device and comprises a raw material gas supply unit, a fixed bed reaction unit, a low-temperature trapping unit, a partial pressure purification unit and a tail gas treatment unit which are connected in series, the fixed bed reaction unit comprises a fixed bed reactor, a heater and a temperature sensor. According to the invention, CuO catalytic particles modified by high-temperature roasting are selected, and a'quartz wool-quartz sand-catalyst-quartz sand 'composite bed structure design is combined, so that the conversion efficiency and selectivity are remarkably improved; the purification process is optimized, and the product quality reaches the high-end application standard; the device is novel in design, and the sealing performance and stability are greatly improved; operation is simple and controllable, and industrial amplification is easy; and the method is green, safe and environment-friendly and conforms to industrial development guidance.
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