Sodium chondroitin sulfate extraction equipment

Abstract

The utility model discloses sodium chondroitin sulfate extraction equipment, which relates to the technical field of sodium chondroitin sulfate production and comprises a steam explosion device, an enzymolysis device, a centrifugal device and a filtering device which are sequentially connected. The steam explosion device comprises a first tank body, a feeding port formed in the first tank body, a discharging port formed in the bottom of the first tank body and a storage barrel connected with the bottom of the discharging port, and a one-way air inlet assembly is arranged on the first tank body. The enzymolysis device comprises a second tank body, a stirring assembly and a heating assembly arranged on the outer surface of the second tank body; material conveying pipe assemblies for communicating the steam explosion device with the enzymolysis device, the enzymolysis device with the centrifugal device and the centrifugal device with the filtering device are arranged between the steam explosion device and the enzymolysis device, between the enzymolysis device and the centrifugal device and between the centrifugal device and the filtering device; the method has the advantages of low production cost, greenness and no pollution.

Description

Technical Field

[0001] The utility model relates to the technical field of sodium chondroitin sulfate production, in particular to sodium chondroitin sulfate extraction equipment. Background Art

[0002] Chondroitin sulfate (CS) is a glycosaminoglycan from animal cartilage tissue, composed of disaccharide units of D-glucuronic acid (Glc A) and N-acetylgalactosamine (Gal NAc) with different sulfates. Its main application in medicine is as a drug for treating joint diseases, which has the effects of relieving pain and promoting cartilage regeneration; at the same time, it is used to treat neuralgia, tinnitus, promote ulcer healing and prevent hyperlipidemia. It also has anticoagulant and anti-vascular sclerosis activities, and has a good effect on the prevention and treatment of cardiovascular diseases such as coronary heart disease and myocardial infarction, and has a protective effect on corneal collagen fibers, nerve cells, kidney cells, etc.

[0003] Chondroitin sulfate exists mainly in the form of glycoprotein in cartilage tissue. To extract chondroitin sulfate, it needs to be separated from protein. At present, there are three main methods for producing chondroitin sulfate: salting method, alkaline hydrolysis method and enzymatic hydrolysis method. The traditional process is: cartilage cooking, alkaline extraction, enzyme hydrolysis, hydrogen peroxide decolorization, alcohol precipitation, refining, and chondroitin sulfate finished product. The alkaline enzymatic hydrolysis production process has cumbersome steps and a long cycle, generally taking 3 to 5 days, and the product quality and yield are unstable. During the high-temperature cooking, alkaline extraction, enzymatic hydrolysis and decolorization process, chondroitin sulfate is severely damaged, the product yield is low, the solution color is deepened, the ethanol consumption is large, the environment is damaged and the production cost is high, a large amount of salt is generated and needs to be desalted, which prolongs the production time and causes environmental pollution. Utility Model Content

[0004] In order to overcome the shortcomings of the background technology, the utility model provides a sodium chondroitin sulfate extraction device which has low production cost and is green and pollution-free.

[0005] The technical scheme adopted by the utility model is: a sodium chondroitin sulfate extraction device, which comprises a steam explosion device, an enzymolysis device, a centrifugal device and a filtering device connected in sequence, wherein the steam explosion device comprises a first tank body, a material inlet arranged on the first tank body, a material outlet arranged at the bottom of the first tank body and a material storage cylinder connected to the bottom of the material outlet, the first tank body is provided with a one-way air inlet component, the enzymolysis device comprises a second tank body, a stirring component and a heating component arranged on the outer surface of the second tank body, and a material delivery pipe component connecting the steam explosion device and the enzymolysis device, between the enzymolysis device and the centrifugal device, and between the centrifugal device and the filtering device is provided.

[0006] An exhaust component is also provided on the top of the first tank body, and the exhaust component adopts an exhaust pipe with a solenoid valve.

[0007] The one-way air intake assembly comprises a plurality of air intake pipes arranged on the side wall of the first tank body and a plurality of one-way switch plates hingedly installed on the inner side wall of the first tank body, wherein the one-way switch plates cover the ends of the air intake pipes.

[0008] The centrifugal device includes a box body, a rotating barrel rotatably installed in the box body, a separation screen cylinder fixedly connected to and communicated with the rotating barrel, and a driving member driving the rotating barrel to rotate. A feeding pipe connected to the rotating barrel is provided on the box body, and a discharging pipe is provided at the lower end of the box body.

[0009] The separation screen cylinder and the rotating barrel are arranged tilted.

[0010] The filtering device comprises a third tank body and a filtering net installed in the third tank body.

[0011] The material delivery pipe assembly comprises a pump body and a delivery pipe.

[0012] The beneficial effects of the utility model are as follows: the technical solution reduces costs and waste of resources by adopting the gas explosion method for the preliminary processing of cartilage, can improve the utilization rate of raw materials, and has the advantages of low energy consumption, high efficiency and no pollution; the composite neutral protease is adopted to avoid the use of acid and alkali and reduce pollution to the environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a schematic diagram of the structure of the sodium chondroitin sulfate extraction equipment of the utility model embodiment. DETAILED DESCRIPTION

[0014] The following is a further description of the embodiments of the present invention in conjunction with the accompanying drawings:

[0015] As shown in the figure, a sodium chondroitin sulfate extraction device comprises a steam explosion device, an enzymolysis device, a centrifugal device and a filtering device connected in sequence, wherein the steam explosion device comprises a first tank body 1, a feed inlet 2 arranged on the first tank body 1, a discharge port 3 arranged at the bottom of the first tank body 1 and a storage barrel 4 connected to the bottom of the discharge port 3, the first tank body 1 is provided with a one-way air intake assembly, the enzymolysis device comprises a second tank body 5, a stirring assembly 20 and a heating assembly 6 arranged on the outer surface of the second tank body 5, and a feed pipe assembly connecting the steam explosion device and the enzymolysis device, between the enzymolysis device and the centrifugal device, and between the centrifugal device and the filtering device is provided; the technical solution reduces costs and waste of resources by adopting a gas explosion method for the preliminary processing of cartilage, can improve the utilization rate of raw materials, and has the advantages of low energy consumption, high efficiency and no pollution, etc.; the composite neutral protease is adopted to avoid the use of acid and alkali, and reduce pollution to the environment.

[0016] An exhaust component 7 is also provided on the top of the first tank body 1. The exhaust component 7 adopts an exhaust pipe with a solenoid valve. The one-way air intake assembly includes a plurality of air intake pipes 8 arranged on the side wall of the first tank body 1 and a plurality of one-way switch plates 9 hingedly installed on the inner wall of the first tank body 1. The one-way switch plates 9 cover the ends of the air intake pipes 8, and steam is filled into the first tank body from the air intake pipes. The multiple air intake pipes allow steam to enter evenly from multiple directions to perform preliminary treatment on the cartilage tissue. The one-way switch plates can prevent steam from flowing back to ensure safety.

[0017] After steam explosion, the cartilage tissue needs to enter the second tank for enzymatic hydrolysis. The composite neutral protease is used to fully enzymatically hydrolyze the cartilage tissue under the action of the stirring component and the heating component. In this embodiment, the stirring component uses a motor to drive the stirring paddle to rotate, and the heating component uses electric heating.

[0018] The centrifugal device includes a housing 10, a rotating barrel 11 rotatably installed in the housing 10, a separation screen drum 12 fixedly connected to and communicated with the rotating barrel 11, and a driving member 13 driving the rotating barrel 11 to rotate. A feeding pipe 14 connected to the rotating barrel 11 is provided on the housing 10, and a discharging pipe 15 is provided at the lower end of the housing 10. The centrifugal device plays a centrifugal role.

[0019] The separation screen drum 12 and the rotating barrel 11 are arranged obliquely, which has the advantage of good separation effect.

[0020] The filtering device comprises a third tank body 16 and a filter screen 17 installed in the third tank body. After enzymolysis, the enzymolysis solution is centrifuged by a centrifugal device and filtered by a filtering device to obtain a semi-finished sodium chondroitin sulfate, and then evaporated and freeze-dried to obtain a finished sodium chondroitin sulfate.

[0021] The material delivery pipe assembly includes a pump body 18 and a delivery pipe 19 .

[0022] In the description of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0023] In the description of the present utility model, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances. In addition, in the description of the present utility model, unless otherwise specified, "plurality" means two or more.

[0024] Technical personnel should note: Although the utility model has been described according to the above specific implementation methods, the utility model concept is not limited to this utility model. Any modification using the utility model concept will be included in the scope of protection of this patent.

Claims

1. A sodium chondroitin sulfate extraction device, characterized in that: The invention comprises a steam explosion device, an enzymolysis device, a centrifugal device and a filtering device which are connected in sequence. The steam explosion device comprises a first tank body (1), a material inlet (2) arranged on the first tank body (1), a material outlet (3) arranged at the bottom of the first tank body (1) and a material storage barrel (4) connected to the bottom of the material outlet (3). The first tank body (1) is provided with a one-way air inlet assembly. The enzymolysis device comprises a second tank body (5), a stirring assembly (20) and a heating assembly (6) arranged on the outer surface of the second tank body (5). A material delivery pipe assembly connecting the steam explosion device and the enzymolysis device, between the enzymolysis device and the centrifugal device, and between the centrifugal device and the filtering device is provided.

2. The sodium chondroitin sulfate extraction equipment according to claim 1, characterized in that: An exhaust component (7) is also provided on the top of the first tank body (1); the exhaust component (7) is an exhaust pipe with a solenoid valve.

3. The sodium chondroitin sulfate extraction equipment according to claim 1, characterized in that: The one-way air intake assembly comprises a plurality of air intake pipes (8) arranged on the side wall of the first tank body (1) and a plurality of one-way switch plates (9) hingedly mounted on the inner side wall of the first tank body (1), wherein the one-way switch plates (9) cover the ends of the air intake pipes (8).

4. The sodium chondroitin sulfate extraction equipment according to claim 1, characterized in that: The centrifugal device comprises a housing (10), a rotating barrel (11) rotatably mounted in the housing (10), a separation screen drum (12) fixedly connected to the rotating barrel (11) and communicated with the rotating barrel (11), and a driving member (13) driving the rotating barrel (11) to rotate, wherein a feed pipe (14) communicating with the rotating barrel (11) is provided on the housing (10), and a discharge pipe (15) is provided at the lower end of the housing (10).

5. The sodium chondroitin sulfate extraction equipment according to claim 4, characterized in that: The separation screen drum (12) and the rotating barrel (11) are arranged at an incline.

6. The sodium chondroitin sulfate extraction equipment according to claim 1, characterized in that: The filtering device comprises a third tank body (16) and a filtering screen (17) installed in the third tank body.

7. The sodium chondroitin sulfate extraction equipment according to claim 1, characterized in that: The material delivery pipe assembly comprises a pump body (18) and a delivery pipe (19).

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