Honeycomb nanofiber-based flexible probe medical dressing

By designing a honeycomb nanofiber-based flexible probe medical dressing, combined with fluorescent probes and near-infrared-responsive drug release, the infection detection and treatment problems of wounds after skin tumor resection are solved, and efficient infection monitoring and antibacterial effects are achieved.

CN223232899UActive Publication Date: 2025-08-19GUANGXI UNIV
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Patent Information

Application Number
CN202223084175.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2022-11-21
Publication Date
2025-08-19
Estimated Expiration
2032-11-21

AI Technical Summary

Technical Problem

The prior art is difficult to achieve efficient infection detection and treatment at the wound after skin tumor resection, especially monitoring and anti-infection treatment of high reactive oxygen concentrations.

Method used

A honeycomb nanofiber-based flexible probe medical dressing is designed, using the honeycomb-shaped shape of the hexagonal structural units closely arranged, and a fluorescent probe based on the stable gold nanoclusters of cellulose nanocrystals is used as the detection part to monitor high reactive oxygen concentration, and the near-infrared and pH-double-responsive cellulose nanofiber nanocage wound dressing is used as the treatment part to achieve controlled release of drugs to kill residual tumor cells and resist bacterial invasion.

Benefits of technology

It realizes efficient infection detection and treatment of wounds after skin tumor resection, and can judge the infection status based on changes in fluorescence intensity. At the same time, it achieves rapid and effective anti-infection and antibacterial effects through controlled release of drugs, avoiding re-damage to new epithelial tissue.

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Abstract

The utility model provides a honeycomb nanofiber-based flexible probe medical dressing, the shape of the medical dressing is a honeycomb formed by closely arranging hexagonal structure units, six edges of each hexagonal structure unit are detection parts, the middle surrounded part is a treatment part, and the detection parts are closely attached to the treatment part; the detection part is used for detecting the high active oxygen concentration of the wound and judging whether the wound is infected or not; the treatment part is used for treatment and infection resistance of wounds after skin tumor excision. The medical dressing is used for wound treatment and infection resistance after skin tumor excision, and meanwhile, the high active oxygen concentration of a wound is detected, and whether the wound is infected or not is judged.
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