A double-end rod sleeve sampling and detecting integrated device

Abstract

The utility model discloses a double -end rod cover sampling detection integration device, including collection detection rod and double -end rod cover, and collection detection rod includes the rod body, middle cover, sampling rod who is detachably assembled as an organic whole in proper order, and double -end rod cover includes the first cavity and the second cavity who do not communicate with each other, and the sampling column of sampling rod is detachably inserted into the first cavity, and the second cavity is by sealed liquid storage cavity and one end opening's sampling cavity is composed, and is sealed through the sealing film between, and the sealing film can be sampled column puncture, and sampling rod is equipped with liquid channel, and the middle cover is equipped with the liquid guide channel and the rod body assembly cavity who communicate, and the liquid channel and liquid guide channel communicate, and the rod body is inserted into the rod body assembly cavity, and is equipped with detection channel and test strip in the rod body, and the entrance of detection channel communicates with the rod body assembly cavity of middle cover. The utility model realizes sampling detection two in one, and the step of additional liquid transfer, mixing, sampling detection again after specimen collection is not needed, reduces the cross -contamination in the operation process, and the operation is simple and convenient.

Description

Technical Field

[0001] This utility model relates to the field of testing instruments, and in particular to an integrated device for sampling and testing with a double-headed rod sleeve. Background Technology

[0002] In the field of in vitro diagnostics, the testing process for liquid specimens mainly consists of two stages: sample collection and specimen testing. Specifically, operators first collect samples using a collection unit, such as collecting nasopharyngeal mucosal secretions with a throat swab or collecting blood samples. The samples obtained by the collection unit generally cannot be tested directly; instead, they need to be transferred to a buffer solution or functional reagent. The sample is then mixed with the buffer solution or functional reagent by stirring or shaking. This process aims to stabilize the target components in the sample, or to release or activate the target components, thereby ensuring that the sample meets the testing requirements. Subsequently, the mixed solution is transferred to a testing device, such as a test strip or test kit. Taking a colloidal gold immunoassay test strip as an example, the mixed solution is added to the sample application area of ​​the test strip. The solution flows forward along the test strip under the action of a capillary. When the solution containing the target substance flows through the test line area, if the target substance is present in the sample, it will specifically bind to the labeled reagent on the test line, producing a color change, causing the test line to appear. Simultaneously, control lines are used to verify the effectiveness of the testing process and ensure the reliability of the results. By observing and analyzing the colorimetric reaction, operators can quickly and accurately obtain test results.

[0003] However, in actual operation, the solution transfer step between sample collection and testing presents several challenges. Some operators, due to insufficient experience, fail to carefully read the instructions or engage in improper procedures, such as not strictly adhering to prescribed sample measurements, inconsistent transfer techniques leading to spillage, inadequate sample mixing, or secondary contamination during transfer. These issues can cause deviations in test results, reducing their accuracy and reliability, thus undermining the credibility of liquid sample testing and hindering its clinical application. Furthermore, the transfer process reduces testing efficiency and wastes time.

[0004] Therefore, improvements in the integration of liquid sample collection and testing are particularly important. By implementing an integrated design, many problems caused by human error can be effectively reduced, the risk of contamination can be lowered, the accuracy of test results can be improved, the efficiency and accuracy of the entire testing process can be ensured, and testing efficiency can be increased. This has positive implications for improving in vitro diagnostics and ensuring the quality of medical testing. Utility Model Content

[0005] The purpose of this invention is to provide an integrated sampling and testing device with a double-ended rod sleeve, which integrates liquid sample collection and testing into one device. After the sample is collected, the mixing process of the sample with buffer solution or functional reagent and the testing process are all completed inside the integrated device, simplifying the operation steps and reducing the risk of secondary contamination from the outside.

[0006] The technical solution adopted in this utility model is:

[0007] A dual-ended rod-sleeve integrated sampling and detection device includes a sampling and detection rod and a dual-ended rod sleeve. The sampling and detection rod sequentially comprises a rod body, a middle sleeve, and a sampling rod that are detachably assembled as a single unit. The dual-ended rod sleeve includes a first cavity and a second cavity that are not interconnected. Both the first cavity and the second cavity are hollow cylinders that are open at one end and closed at the other. The sampling rod includes a sampling column for sampling, which is detachably inserted into the first cavity. The second cavity consists of a sealed liquid storage chamber and a sampling chamber that is open at one end. The liquid storage chamber is connected to... The sampling chambers are sealed with a sealing film to seal the liquid storage chamber; the sealing film can be pierced by the sampling column, allowing the sampling column to be inserted into the liquid storage chamber; the liquid storage chamber is filled with liquid reagent; the sampling rod has a liquid channel, and the inner sleeve has a communicating liquid guiding channel and a rod body assembly cavity, the liquid channel and the liquid guiding channel are connected, and the rod body is inserted into the rod body assembly cavity; the rod body has a detection channel for placing the test strip; the rod body has a transparent window for displaying the test strip detection result; the entrance of the detection channel is connected to the rod body assembly cavity of the inner sleeve.

[0008] The liquid channel of the sampling rod can be a guide groove or a core channel penetrating the sampling rod.

[0009] The outlet of the liquid channel is connected to the inlet of the detection channel.

[0010] Before use, the sampling rod is inserted into the first cavity. When in use, it is removed, and a biological sample is collected using the sampling rod. Then, the sealing film is pierced and the rod is inserted into the liquid storage cavity. The collected sample is released into the liquid in the liquid storage cavity, resulting in sampling liquid. The sampling liquid is squeezed out of the liquid storage cavity by the sampling rod and enters the liquid channel of the sampling rod. After passing through the liquid guiding channel of the middle sleeve, it enters the rod body assembly cavity and enters the rod body through the detection channel inlet. The sample is then applied to the sample injection end of the test strip, and the test result is read from the transparent window.

[0011] The rod body and the middle sleeve, and the middle sleeve and the sampling rod are each detachably assembled via a snap-fit ​​structure.

[0012] The sampling column and the reservoir can be fitted with a clearance fit. The length of the sampling column matches the depth of the reservoir, and the outer diameter of the sampling column matches the inner diameter of the reservoir. The gap between the outer wall of the sampling column and the inner wall of the reservoir is small, so that when the sampling column is inserted into the reservoir, the liquid in the reservoir is squeezed out and can enter the liquid channel of the sampling rod. The sampling column can be completely inserted into the reservoir.

[0013] The middle sleeve consists of a liquid guiding part and an assembly part, both of which are hollow cylinders. The liquid guiding part has a liquid guiding channel with openings at both ends, and the assembly part has a rod body assembly cavity with openings at both ends; the liquid guiding channel and the rod body assembly cavity are interconnected.

[0014] The liquid guiding part and the sampling rod are detachable and can be assembled. After assembly, the sampling column is located at the front end of the liquid guiding part. The liquid guiding part and the sampling column can be inserted into the first cavity or the second cavity. When the sampling column is inserted into the liquid storage cavity of the second cavity, the liquid guiding part is inserted into the sampling cavity.

[0015] The assembly part and the rod body are detachably assembled; generally, the rod body is inserted into the rod body assembly cavity and is detachably assembled with the assembly part.

[0016] Generally, the liquid guiding part and the sampling rod are detachably assembled using a snap-fit ​​structure, and the assembly part and the rod body are detachably assembled using a snap-fit ​​structure.

[0017] The liquid guiding part is clearance-fitted with the first cavity or sampling cavity, and the first cavity or sampling cavity can be sealed by the middle sleeve sealing ring provided on the outer wall of the liquid guiding part.

[0018] Before use, the sampling rod inserts its sampling column into the first cavity, and the liquid guiding part of the middle sleeve is also inserted into the first cavity and sealed, thus isolating the sampling column at the front end of the liquid guiding part from the external environment and preventing contamination. When the sampling column is inserted into the liquid storage cavity, the liquid guiding part is inserted into the sampling cavity and seals the sampling cavity to prevent the liquid squeezed out of the liquid storage cavity by the sampling column from overflowing to the outside of the second cavity.

[0019] Specifically, the outer diameter of the liquid guiding part is closely matched with the inner diameter of the first cavity or sampling cavity, so that the gap is small after the liquid guiding part is inserted into the first cavity or sampling cavity, and the middle sealing ring provided on the outer wall of the liquid guiding part can tightly fit the inner wall of the first cavity or sampling cavity, sealing the first cavity or sampling cavity.

[0020] Furthermore, at the connection between the connecting part and the liquid guiding part, a groove for the intermediate sleeve sealing ring is provided on the outer wall of the column body. The groove for the intermediate sleeve sealing ring is used to place the intermediate sleeve sealing ring.

[0021] The liquid guiding section has a connecting portion at its end, which is a column at the end of the liquid guiding section facing the opening of the sampling rod. On the end face of the connecting portion, at least one recessed liquid inlet groove is distributed circumferentially. The liquid inlet groove penetrates the end face of the connecting portion radially, with one end of the liquid inlet groove communicating with the liquid guiding channel and the other end communicating with the first cavity or the second cavity. The liquid inlet groove is used to guide the sampling liquid squeezed out of the liquid storage cavity by the sampling column into the liquid guiding channel.

[0022] The inner wall of the connecting part may be provided with a snap-fit ​​structure, such as a raised step, for snap-fitting with the sampling rod.

[0023] Optionally, at the connection between the liquid guiding part and the assembly part, an outwardly protruding limiting part is provided; the limiting part is used to limit the depth of the sampling rod and the liquid guiding part inserted into the first cavity or the second cavity.

[0024] Generally, after the liquid guiding part and the sampling rod are assembled, the distance between the limiting part of the middle sleeve and the end of the sampling column is adapted to the depth of the first or second cavity. That is, the total length of the liquid guiding part and the sampling column is adapted to the depth of the first or second cavity.

[0025] The sampling rod includes a sampling part and a sampling rod body. One end of the sampling rod body is a sampling column body, and the other end is a flow guide rod body. The sampling part is located on the sampling column body to form the sampling column. The flow guide rod body is inserted into the liquid guiding channel of the middle sleeve and is detachably assembled with the liquid guiding part of the middle sleeve.

[0026] The sampling rod body is a solid column or a hollow column. When the sampling rod body is a solid column, the sampling part is located on the outer layer of the sampling column body. The guide rod body is provided with at least one recessed guide groove along the axial direction as a liquid channel. The inlet of the guide groove is connected to the liquid inlet groove at the end of the middle sleeve, and the outlet of the guide groove is close to the inlet of the detection channel.

[0027] After the sampling liquid is squeezed out by the sampling column, it enters the guide channel through the liquid inlet at the end of the middle sleeve, and then enters the rod assembly cavity through the liquid guide channel of the middle sleeve, and finally enters the detection channel inlet of the rod body.

[0028] When the sampling rod is a hollow column, the inside of the sampling rod has a hollow inner core channel that runs through the sampling rod, which is a liquid channel; one end of the inner core channel has a sampling part, and the head of the sampling part protrudes from the opening of the inner core channel; the outlet at the other end is close to the inlet of the detection channel; after the sampling rod is inserted into the liquid storage chamber, the liquid in the liquid storage chamber can directly enter the inner core channel through the sampling part, pass through the inner core channel into the rod assembly cavity, and enter the inlet of the detection channel of the rod.

[0029] The guide rod body is either a solid or hollow column, corresponding to the solid or hollow column body of the sampling column.

[0030] The sampling unit is made of porous materials, such as elastic porous sponge or porous fiber. The sampling unit can employ a hydrophilic polymer sampling head, which, through capillary action, can collect quantitative liquid samples.

[0031] The sampling column is a columnar structure at one end of the sampling rod, with the end being planar or conical, and the interior being solid or hollow.

[0032] When the sampling rod is a solid column, the sampling part is located on the outer layer of the sampling column. The sampling part can completely cover the outer wall of the sampling column (exposing the end face), or completely cover the outer wall and end of the sampling column.

[0033] When the sampling section is made of an elastic porous material, the sampling column and the liquid storage chamber can be interference fit. The inner diameter of the liquid storage chamber is larger than the diameter of the sampling column body, but slightly smaller than the total diameter of the sampling column body and the sampling section. This allows the sampling section to be squeezed by the inner wall of the liquid storage chamber when the sampling column is inserted into the liquid storage chamber, which is conducive to the release and mixing of the sample collected in the sampling section.

[0034] When the sampling rod is a hollow column, the sampling part is located inside the inner core channel and at one end close to the sampling column. The head of the sampling part is partially exposed outward from the end opening of the sampling column. The sampling column and the liquid storage chamber are fitted with a clearance. The outer diameter of the sampling column is slightly smaller than the inner diameter of the liquid storage chamber, so that the sampling column can be inserted into the liquid storage chamber. The space between the sampling column and the liquid storage chamber is small, which facilitates the liquid in the liquid storage chamber to enter the inner core channel and the flow channel.

[0035] The guide rod body and the liquid guiding channel of the middle sleeve can be detachably assembled through a snap-fit ​​structure, and the guide rod body and the liquid guiding channel are fitted with a clearance.

[0036] Furthermore, a step or groove is provided between the sampling column and the guide rod body for engaging with the snap-fit ​​structure of the middle sleeve. When the guide rod body is inserted into the liquid guiding channel of the middle sleeve, the two achieve a stable connection through the engagement of the snap-fit ​​and the groove.

[0037] The guide rod body and the liquid guiding channel are fitted with a clearance. Specifically, the outer diameter of the guide rod body matches the inner diameter of the liquid guiding part of the middle sleeve (the inner diameter of the guide channel). The outer diameter of the guide rod body is slightly smaller than the inner diameter of the guide channel, so that the guide rod body can be tightly inserted into the guide channel; and the gap between the outer wall of the guide rod body and the inner wall of the guide channel is small.

[0038] The length of the guide rod is matched to the depth of the liquid guiding channel, and the guide rod is tightly fitted to the rod body inserted into the rod body assembly cavity. That is, the guide rod is tightly fitted to the inlet of the detection channel of the rod body.

[0039] The double-ended rod sleeve includes a detachably fitted first rod head and a second rod head. One end of the first rod head has an open first cavity, and the other end has a sealed liquid storage cavity. The first cavity and the liquid storage cavity are not in communication. The open end of the first cavity and the sealing film are located at the two ends of the first rod head, respectively. The second rod head is a hollow cavity with open ends. One end is a sampling cavity, and the other end is an assembly cavity. The liquid storage cavity of the first rod head is inserted into the assembly cavity of the second rod head and is detachably fitted with the second rod head. The outer wall of the liquid storage cavity is provided with a detachable rod sleeve sealing ring for sealing the outer wall of the liquid storage cavity and the assembly cavity.

[0040] The reagents in the reservoir can be buffer solutions, lysis buffers, activation solutions, or other functional reagents required for detection, and are not limited to those listed above.

[0041] The liquid storage chamber of the first rod head can be inserted into the assembly chamber of the second rod head, allowing for detachable assembly. Generally, a snap-fit ​​assembly is used. Other detachable assembly methods, such as threads, can also be employed.

[0042] The length of the liquid storage cavity is matched with the depth of the assembly cavity.

[0043] Furthermore, a limiting block is provided between the sampling chamber and the assembly chamber to divide the two spaces. The position of the limiting block controls the depth of the assembly chamber, thereby limiting the insertion depth of the liquid storage chamber.

[0044] The limiting block is a step protruding inward from the inner wall of the assembly cavity. The end face of the cylinder inserted into the assembly cavity abuts against the limiting block.

[0045] Furthermore, the outer wall of the liquid storage cavity is provided with a groove for the rod sleeve sealing ring, which is adapted to the rod sleeve sealing ring. The rod sleeve sealing ring is used to seal the outer wall of the liquid storage cavity and the assembly cavity. Specifically, the rod sleeve sealing ring of the liquid storage cavity is adapted to the inner diameter of the assembly cavity. The rod sleeve sealing ring can fit tightly against the inner wall of the assembly cavity and seal the gap between the outer wall of the liquid storage cavity and the assembly cavity. When the sampling rod is inserted into the second cavity and pierces the sealing film and is inserted into the liquid storage cavity, the rod sleeve sealing ring prevents the liquid in the liquid storage cavity from leaking into the gap between the outer wall of the liquid storage cavity and the assembly cavity.

[0046] Furthermore, the rod body is composed of an upper plate and a lower plate that are snapped together. A hollow detection channel with one open end is provided between the upper plate and the lower plate. The detection channel is used to place the test strip. The entrance of the detection channel is connected to the rod body assembly cavity of the middle sleeve.

[0047] The upper plate is equipped with a transparent window for displaying the test strip results; the transparent window is generally located in the C-line and T-line area of ​​the test strip to facilitate observation of the test results.

[0048] The rod body has an insertion part at one end near the middle sleeve. The insertion part is inserted into the rod body assembly cavity of the middle sleeve and is detachably assembled with the middle sleeve. The insertion part and the rod body assembly cavity of the middle sleeve are generally engaged by a snap-fit.

[0049] In this device, the inlet of the detection channel is in close contact with the outlet of the liquid channel, and the sample injection end of the test strip is close to the inlet of the detection channel.

[0050] Specifically, the length of the insertion part of the rod body is adapted to the depth of the rod body assembly cavity, and the guide rod body in the middle sleeve is in close contact with the rod body insertion part inserted into the rod body assembly cavity.

[0051] The sample inlet of the test strip should be as close as possible to the entrance of the detection channel so that the sampling liquid enters the stick and wets the test strip through the shortest distance before being applied to the sample.

[0052] The dual-ended rod sleeve sampling and detection integrated device provided by this utility model integrates functional reagents such as buffer solution and lysis solution into the dual-ended rod sleeve. After the sampling rod collects the liquid sample, the sampling rod is inserted into the second cavity, so that the sample collected on the sampling rod is released into the liquid reagent and mixed. Then, it enters the rod body assembly cavity of the middle sleeve through the guide groove or inner core channel, enters the rod body through the detection channel inlet of the rod body, and is applied to the test strip.

[0053] This invention utilizes a double-ended rod sleeve to achieve a two-in-one sampling and detection process, eliminating the need for additional steps such as liquid transfer, mixing, and re-sampling after sample collection, thus reducing cross-contamination during operation; it is also simple to use.

[0054] The sampling sticks can be replaced according to different biological sample sampling needs, meeting the specimen collection requirements of various scenarios. This device is simple to operate, and the collection and sample injection detection steps are less susceptible to operator interference, improving the accuracy and consistency of the test results. Attached Figure Description

[0055] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0056] Figure 1 This is an exploded view of the integrated sampling and testing device with a double-headed rod sleeve.

[0057] Figure 2 This is a structural diagram of the assembled dual-headed rod sleeve sampling and testing integrated device.

[0058] Figure 3 This is a schematic diagram of the cross-sectional structure of a double-ended rod sleeve.

[0059] Figure 4 This is a schematic diagram of the middle sleeve structure.

[0060] Figure 5 This is a schematic diagram of the cross-sectional structure of the inner sleeve.

[0061] Figure 6 This is a schematic diagram of one embodiment of the sampling rod.

[0062] Figure 7 This is a schematic diagram of the cross-sectional structure of the sampling rod in different implementations.

[0063] Figure 8 A schematic diagram illustrating the usage steps of the integrated sampling and testing device with a double-headed rod sleeve.

[0064] In the diagram: 100, Rod body; 101, Upper plate; 102, Transparent window; 103, Test strip; 104, Lower plate; 105, Detection channel; 106, Insertion part; 200, Middle sleeve; 201, Assembly part; 2015, Rod body assembly cavity; 202, Liquid guiding part; 2021, Connecting part; 2022, Middle sleeve connecting part snap-fit ​​structure; 2023, Liquid inlet groove; 2024, Middle sleeve sealing ring groove; 2025, Liquid guiding channel; 203, Middle sleeve sealing ring; 204, Limiting part; 300, Sampling rod; 3 01. Sampling rod body; 3011. Sampling column body; 3012. Guide rod body; 3013. Guide groove; 3014. Snap-on step; 302. Sampling section; 303. Inner core channel; 304. Sampling column; 400. Double-headed rod sleeve; 401. First rod head; 4011. First cavity; 4012. Liquid storage cavity; 4013. Rod sleeve sealing ring groove; 4014. Limiting block; 402. Rod sleeve sealing ring; 403. Sealing film; 404. Second rod head; 4041. Sampling cavity; 4042. Assembly cavity. Detailed Implementation

[0065] The specific embodiments of this utility model will now be described in detail with reference to the accompanying drawings. Obviously, the described embodiments are merely some, not all, of the embodiments of this utility model. Based on the description of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0066] In the description of this utility model, unless otherwise explicitly specified and limited, the terms "set up," "equipped with," "located in," "installed," and "connected," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms according to the specific circumstances.

[0067] The terms “end,” “side,” “outer side,” “top,” and “bottom,” etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship in which the product of this utility model is usually placed during use. They are only for the convenience of description and simplification, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0068] In the description of this utility model, unless otherwise expressly specified and limited, the terms "first", "second", etc. are used only to distinguish elements with similar properties, and not to indicate or imply relative importance or a specific order.

[0069] The term “include” or any other variation thereof is intended to cover non-exclusive inclusion, which includes not only those elements listed, but also other elements not expressly listed.

[0070] Example 1

[0071] like Figures 1-6As shown, the device includes a sampling probe and a double-ended probe sleeve 400. The sampling probe sequentially includes a detachably assembled probe body 100, a middle sleeve 200, and a sampling rod 300. The double-ended probe sleeve 400 includes a first cavity 4011 and a second cavity that are not interconnected. Both the first cavity 4011 and the second cavity are hollow cylinders with one end open and the other end closed. The sampling rod 300 includes a sampling column 304 for sampling, which is detachably inserted into the first cavity 4011. The second cavity consists of a sealed liquid storage cavity 4012 and a sampling cavity 4041 open at one end. The liquid storage cavity 4012 and the sampling cavity 4041 are sealed by a sealing film 403. 12; The sealing film 403 can be pierced by the sampling column 304, allowing the sampling column 304 to be inserted into the liquid storage chamber 4012; the liquid storage chamber 4012 is filled with liquid reagent; the sampling rod 300 is provided with a liquid channel, and the middle sleeve 200 is provided with a communicating liquid guiding channel 2025 and a rod body assembly cavity 2015, the liquid channel and the liquid guiding channel 2025 are connected, and the rod body 100 is inserted into the rod body assembly cavity 2015; the rod body 100 is provided with a detection channel 105, which is used to place the test strip 103; the rod body 100 is provided with a transparent window 102 for displaying the test result of the test strip 103; the entrance of the detection channel 105 is connected to the rod body assembly cavity 2015 of the middle sleeve 200.

[0072] Before use, the sampling column 304 of the sampling detection rod is inserted into the first cavity 4011 of the double-ended rod sleeve for storage, so as to maintain the hygienic condition of the sampling column 304 before use and ensure its cleanliness and absence of contamination.

[0073] During sampling, the sampling column 304 is removed from the first cavity 4011 to collect a biological liquid sample. Then, the sampling column 304 is inserted into the sampling cavity 4041 and pierces the sealing film 403. The sampling column 304 enters the liquid storage cavity 4012. The sample collected on the sampling column 304 is released into the liquid in the liquid storage cavity 4012 and mixed to obtain the sampling liquid. The sampling liquid is squeezed out from the liquid storage cavity 4012 by the sampling column 304 and enters the liquid channel of the sampling rod 300. After passing through the liquid guiding channel 2025 of the middle sleeve 200, it enters the rod body assembly cavity 2015 and enters the rod body 100 through the detection channel 105 entrance. The sample is applied to the injection end of the test strip 103, and the test result is read from the transparent window 102.

[0074] The liquid channel of the sampling rod 300 can be a guide groove 3013 or an inner core channel 303 that penetrates the sampling rod 300.

[0075] The outlet of the liquid channel is connected to the inlet of the detection channel 105.

[0076] Preferably, the rod body 100 and the middle sleeve 200, and the middle sleeve 200 and the sampling rod 300 are detachably assembled via a snap-fit ​​structure.

[0077] The sampling column 304 and the liquid storage chamber 4012 can be fitted with a clearance. The length of the sampling column 304 is adapted to the depth of the liquid storage chamber 4012, and the outer diameter of the sampling column 304 is adapted to the inner diameter of the liquid storage chamber 4012. The gap between the outer wall of the sampling column 304 and the inner wall of the liquid storage chamber 4012 is small, so that when the sampling column 304 is inserted into the liquid storage chamber 4012, the liquid in the liquid storage chamber 4012 is squeezed out and can enter the liquid channel of the sampling rod 300. The length of the sampling column 304 is adapted to the depth of the liquid storage chamber 4012, so that the sampling column 304 can be completely inserted into the liquid storage chamber 4012.

[0078] Furthermore, the middle sleeve 200 is composed of a liquid guiding part 202 and an assembly part 201, both of which are hollow cylinders. The liquid guiding part 202 is provided with a liquid guiding channel 2025 with openings at both ends, and the assembly part 201 is provided with a rod body assembly cavity 2015 with openings at both ends; the liquid guiding channel 2025 and the rod body assembly cavity 2015 are interconnected.

[0079] The liquid guiding part 202 and the sampling rod 300 are detachably assembled. After assembly, the sampling column 304 is located at the front end of the liquid guiding part 202. The liquid guiding part 202 and the sampling column 304 can be inserted into the first cavity 4011 or the second cavity. When the sampling column 304 is inserted into the liquid storage cavity 4012 of the second cavity, the liquid guiding part 202 is inserted into the sampling cavity 4041.

[0080] The assembly part 201 and the rod body 100 are detachably assembled;

[0081] Generally, the liquid guiding part 202 and the sampling rod 300 are detachably assembled through a snap-fit ​​structure, and the assembly part 201 and the rod body 100 are detachably assembled through a snap-fit ​​structure.

[0082] The liquid guiding part 202 is clearance-fitted with the first cavity 4011 or the sampling cavity 4041, and the first cavity 4011 or the sampling cavity 4041 can be sealed by the middle sleeve sealing ring 203 provided on the outer wall of the liquid guiding part 202.

[0083] Before use, the sampling rod 300 has its sampling column 304 inserted into the first cavity 4011, and the liquid guiding part 202 of the middle sleeve 200 is also inserted into the first cavity 4011, sealing the first cavity 4011. This isolates the sampling column 304 at the front end of the liquid guiding part 202 from the external environment, preventing contamination. When the sampling column 304 is inserted into the liquid storage cavity 4012, the liquid guiding part 202 is inserted into the sampling cavity 4041 and seals the sampling cavity 4041, preventing the liquid squeezed out of the liquid storage cavity 4012 by the sampling column 304 from overflowing to the outside of the second cavity.

[0084] The liquid guiding part 202 is clearance-fitted with the first cavity 4011 or the sampling cavity 4041. Specifically, the outer diameter of the liquid guiding part 202 is tightly fitted with the inner diameter of the first cavity 4011 or the sampling cavity 4041, so that after the liquid guiding part 202 is inserted into the first cavity 4011 or the sampling cavity 4041, the gap between the outer wall of the liquid guiding part 202 and the inner wall of the first cavity 4011 or the sampling cavity 4041 is small, and the middle sealing ring 203 provided on the outer wall of the liquid guiding part 202 can tightly fit the inner wall of the first cavity 4011 or the sampling cavity 4041, sealing the first cavity 4011 or the sampling cavity 4041. At this time, a seal is formed between the liquid guiding part 202 and the sampling cavity 4041, and the space of the sampling cavity 4041 is occupied by the liquid guiding part 202, the liquid holding space becomes smaller, and the liquid is guided into the liquid channel of the sampling rod 300.

[0085] The liquid guiding part 202 has a connecting part 2021 at its end. The connecting part 2021 is a cylindrical part at the end of the liquid guiding part 202 facing the opening of the sampling rod 300. The connecting part 2021 is a hollow cylindrical part. On the cylindrical end face of the connecting part 2021, at least one recessed liquid inlet groove 2023 is distributed circumferentially. The liquid inlet groove 2023 penetrates the end face of the connecting part 2021 radially. One end of the liquid inlet groove 2023 facing inward is connected to the liquid guiding channel 2025, and the other end faces outward, connecting to the first cavity 4011 or the second cavity. The liquid inlet groove 2023 is used to guide the sampling liquid squeezed out of the liquid storage cavity 4012 by the sampling column 304 into the liquid guiding channel 2025.

[0086] like Figure 4 As shown, in a preferred embodiment, two recessed liquid inlet grooves 2023 are symmetrically provided on the end face of the connecting part 2021.

[0087] The inner wall of the connecting part 2021 may be provided with a snap-fit ​​structure, such as a raised step, or... Figure 4 The snap-fit ​​structure shown in Figure 2022 is used to engage with the sampling rod 300.

[0088] Furthermore, such as Figure 5 As shown, at the connection between the connecting part 2021 and the liquid guiding part 202, a middle sleeve sealing ring groove 2024 adapted to the middle sleeve sealing ring 203 is provided on the outer wall of the column. The middle sleeve sealing ring groove 2024 is used to place the middle sleeve sealing ring 203.

[0089] In a preferred embodiment, such as Figure 4 , 5 As shown, at the connection between the liquid guiding part 202 and the assembly part 201, there is an outwardly protruding limiting part 204; the limiting part 204 is used to limit the depth of the sampling rod 300 and the liquid guiding part 202 inserted into the first cavity 4011 or the second cavity.

[0090] After the liquid guiding part 202 and the sampling rod 300 are assembled, the distance between the limiting part 204 of the middle sleeve 200 and the end of the sampling column is adapted to the depth of the first cavity 4011 or the second cavity. That is, the total length of the liquid guiding part 202 and the sampling rod 304 is adapted to the depth of the first cavity 4011 or the second cavity.

[0091] Depending on the biological sample collected, the sampling rod 300 can have various structural forms, but the basic structure is the same. The sampling rod 300 includes a sampling part 302 and a sampling rod body 301. The sampling rod body 301 is composed of a sampling column body 3011 and a flow guiding rod body 3012, which are located at opposite ends, i.e., one end is the sampling column body 3011 and the other end is the flow guiding rod body 3012. The sampling part 302 is located on the sampling column body 3011 to form the sampling column 304. The flow guiding rod body 3012 is inserted into the liquid guiding channel 2025 of the middle sleeve 200 and can be detachably assembled with the middle sleeve 200.

[0092] The sampling rod body 301 is a solid column or a hollow column. When the sampling rod body 301 is a solid column, the sampling part 302 is located on the outer layer of the sampling rod body 3011. The guide rod body 3012 is provided with at least one recessed guide groove 3013 along the axial direction as a liquid channel. The inlet of the guide groove 3013 is connected to the liquid inlet groove 2023 at the end of the middle sleeve 200, and the outlet of the guide groove 3013 is close to the inlet of the detection channel 105.

[0093] During use, the sampled liquid is squeezed out by the sampling column 304, passes through the liquid inlet 2023 at the end of the middle sleeve 200, enters the guide channel 3013, enters the rod body assembly cavity 2015 through the liquid guide channel 2025 of the middle sleeve 200, and enters the detection channel 105 inlet of the rod body 100.

[0094] When the sampling rod body 301 is a hollow cylinder, the sampling rod body 301 has a hollow inner core channel 303 that runs through the sampling rod body 301, which is a liquid channel; one end of the inner core channel 303 is provided with a sampling part 302, and the head of the sampling part 302 protrudes from the opening of the inner core channel 303; the outlet of the other end is close to the inlet of the detection channel 105; the liquid in the liquid storage chamber 4012 enters the inner core channel 303 directly through the sampling part 302, passes through the inner core channel 303 and enters the rod body assembly cavity 2015, and enters the inlet of the detection channel 105 of the rod body 100.

[0095] The inner diameter of the inner core channel 303 needs to be controlled so that the liquid in the storage chamber 4012 can pass through the inner core channel 303 and reach the inlet of the detection channel 105. If the inner diameter of the inner core channel 303 is too large, the liquid in the storage chamber 4012 may accumulate in the inner core channel 303 due to its limited volume, and may not be able to enter the inlet of the detection channel 105, thus preventing sample loading.

[0096] The guide rod body 3012 is a solid or hollow column body, corresponding to the solid or hollow column body of the sampling column body 3011.

[0097] The sampling unit 302 is made of a porous material with adsorption properties to achieve effective adsorption and collection of the target sample. The material of the sampling unit 302 can be an elastic porous sponge, porous fiber, etc. The sampling unit 302 generally has hydrophilic properties, and can absorb liquid samples through capillary action upon contact.

[0098] The sampling column 3011 is a columnar structure at one end of the sampling rod 301, with its end being planar or conical, and its interior being solid or hollow.

[0099] The sampling unit 302 and the sampling rod body 301 can have various structural forms. The sampling rod body 301 can be a solid or hollow column. The diameter and length of the sampling rod body can also be adjusted. A suitable sampling rod 300 can be selected according to different sample sampling requirements. Figure 7 Figures A, B, and C show the structures of three different sampling rods.

[0100] In Figures A and C, the sampling rod 301 is a solid cylinder, as shown in 301-1 in Figure A and 301-3 in Figure C. The sampling rod 301 is generally made of inert hard plastic.

[0101] When the sampling rod body 301 is a solid column, the sampling part 302 is located on the outer layer of the sampling column body 3011.

[0102] like Figure 7 As shown in Figure A, the sampling part 302-1 completely covers the outer wall of the sampling column 3011 and exposes the end of the sampling column 3011. The material of the sampling part 302-1 can be an elastic porous sponge with a certain thickness, and the sampling part 302-1 can be fitted onto the sampling column 3011.

[0103] The sampling stick in Figure A is generally used to collect saliva samples from the oral cavity.

[0104] As shown in Figure A, when the sampling section 302-1 is made of an elastic porous material, the sampling column 304 and the liquid storage chamber 4012 can be an interference fit. The inner diameter of the liquid storage chamber 4012 is larger than the diameter of the sampling column body 3011, but slightly smaller than the total diameter of the sampling column body 3011 and the sampling section 302. This allows the sampling section 302-1 to be squeezed by the inner wall of the liquid storage chamber 4012 when the sampling column 304 is inserted into the liquid storage chamber 4012, which is beneficial for the release and mixing of the sample collected in the sampling section 302-1.

[0105] like Figure 7As shown in Figure C, the sampling section 302-1 completely covers the outer wall and end of the sampling column 3011. The sampling section 302-1 can be made of porous sponge and is generally fixedly connected to the sampling column 3011.

[0106] Generally, the sampling rod in Figure C has a smaller diameter (3011) and can be used to collect secretion samples from the nasal cavity and throat.

[0107] Figure 7 In Figure B, the sampling rod body 301-2 is a hollow cylinder. The sampling rod body 301-2 has an inner core channel 303 that runs through it. The sampling part 302-2 is located inside the inner core channel 303 and is located at one end close to the sampling rod body 3011. The head of the sampling part 302-2 is partially exposed outward from the end opening of the sampling rod body 3011.

[0108] In Figure B, the sampling column 304 and the liquid storage cavity 4012 are fitted with a clearance. The outer diameter of the sampling column 304 is slightly smaller than the inner diameter of the liquid storage cavity 4012, which allows the sampling column 304 to be inserted into the liquid storage cavity 4012. The space between the sampling column 304 and the liquid storage cavity 4012 is small, which facilitates the liquid in the liquid storage cavity 4012 to enter the inner core channel 303 and then enter the flow channel.

[0109] The guide rod body 3012 and the liquid guiding channel 2025 of the middle sleeve 200 can be detachably assembled through a snap-fit ​​structure, and the guide rod body 3012 and the liquid guiding channel 2025 are fitted with a clearance.

[0110] Furthermore, a step or groove is provided between the sampling column 304 and the guide rod body 3012 for engaging with the snap-fit ​​structure 2022 of the middle sleeve connection part of the middle sleeve 200, such as... Figure 6 As shown in the snap-fit ​​step 3014, when the guide rod body 3012 is inserted into the liquid guiding channel 2025, the two achieve a stable connection through the cooperation of the snap-fit ​​and the slot.

[0111] The guide rod body 3012 and the liquid guiding channel 2025 are in clearance fit. Specifically, the outer diameter of the guide rod body 3012 matches the inner diameter of the liquid guiding part 202 of the middle sleeve 200 (the inner diameter of the guide channel). The outer diameter of the guide rod body 3012 is slightly smaller than the inner diameter of the guide channel, so that the guide rod body 3012 can be tightly inserted into the guide channel; and the gap between the outer wall of the guide rod body 3012 and the inner wall of the guide channel is small.

[0112] The length of the guide rod 3012 is adapted to the depth of the liquid guiding channel 2025, and the guide rod 3012 is in close contact with the rod 100 inserted into the rod assembly cavity 2015. That is, the guide rod 3012 is in close contact with the inlet of the detection channel 105 of the rod 100. The purpose is to reduce the distance between the outlet of the liquid channel (guide groove 3013 or inner core channel 303) and the inlet of the detection channel 105, reduce the flow distance of the sampling liquid, and facilitate sample loading.

[0113] Generally, one end of the guide rod 3012 inserted into the guide channel is located at the connection between the liquid guide channel 2025 and the rod assembly cavity 2015;

[0114] Correspondingly, one end of the rod body 100 inserted into the rod body assembly cavity 2015 (the inlet of the detection channel 105) is also located at the connection between the liquid guiding channel 2025 and the rod body assembly cavity 2015.

[0115] The double-headed rod sleeve 400 includes a detachably fitted first rod head 401 and a second rod head 404. One end of the first rod head 401 has an open first cavity 4011, and the other end has a sealed liquid storage cavity 4012. The first cavity 4011 and the liquid storage cavity 4012 are not in communication. The open end of the first cavity 4011 and the sealing film 403 are located at the two ends of the first rod head 401, respectively. The second rod head 404 is a hollow cavity with open ends. One end is a sampling cavity 4041, and the other end is an assembly cavity 4042. The liquid storage cavity 4012 of the first rod head 401 and the assembly cavity 4042 of the second rod head 404 are detachably fitted. The outer wall of the liquid storage cavity 4012 is provided with a detachable rod sleeve sealing ring 402 for sealing the outer wall of the liquid storage cavity 4012 and the assembly cavity 4042.

[0116] The inner diameter of the liquid storage chamber 4012 is smaller than the inner diameter of the sampling chamber 4041.

[0117] The reagents in the reservoir 4012 can be buffer solutions, lysis buffers, activation solutions, or other functional reagents required for detection, and are not limited to those listed above.

[0118] The liquid storage cavity 4012 of the first rod head 401 can be inserted into the assembly cavity 4042 of the second rod head 404, allowing for detachable assembly. Generally, a snap-fit ​​assembly is used. Other detachable assembly methods, such as threads, can also be employed.

[0119] In one alternative implementation, such as Figure 3 As shown, a limiting block 4014 is provided between the sampling cavity 4041 and the assembly cavity 4042, which divides the assembly cavity 4042 and the sampling cavity 4041. The position of the limiting block 4014 controls the depth of the assembly cavity 4042, thereby limiting the insertion depth of the liquid storage cavity 4012.

[0120] The length of the liquid storage cavity 4012 is adapted to the depth of the assembly cavity 4042.

[0121] The limiting block 4014 is a step protruding inward from the inner wall of the assembly cavity 4042. The end face of the cylindrical body of the liquid storage cavity 4012 inserted into the assembly cavity 4042 abuts against the limiting block 4014.

[0122] Furthermore, the outer wall of the liquid storage cavity 4012 is provided with a rod sleeve sealing ring groove 4013 adapted to the rod sleeve sealing ring 402. The rod sleeve sealing ring 402 is used to seal the outer wall of the liquid storage cavity 4012 and the assembly cavity 4042. Specifically, the rod sleeve sealing ring 402 of the liquid storage cavity 4012 is adapted to the inner diameter of the assembly cavity 4042. The rod sleeve sealing ring 402 can tightly fit the inner wall of the assembly cavity 4042 and seal the gap between the outer wall of the liquid storage cavity 4012 and the assembly cavity 4042. When the sampling rod 300 is inserted into the second cavity and pierces the sealing film 403 and is inserted into the liquid storage cavity 4012, the rod sleeve sealing ring 402 prevents the liquid in the liquid storage cavity 4012 from leaking into the gap between the outer wall of the liquid storage cavity 4012 and the assembly cavity 4042.

[0123] Furthermore, the rod body 100 is composed of an upper plate 101 and a lower plate 104 that are snapped together. A hollow detection channel 105 with one end open is provided between the upper plate 101 and the lower plate 104. The detection channel 105 is used to place the test strip 103. The entrance of the detection channel 105 is connected to the rod body assembly cavity 2015 of the middle sleeve 200.

[0124] The upper plate 101 is provided with a transparent window 102 for displaying the test results of the test strip 103; the transparent window 102 is generally located in the C-line and T-line area of ​​the test strip 103 for easy observation of the test results. The transparent window 102 is generally made of transparent plastic or glass and is fixed on the upper plate 101.

[0125] The rod body 100 is provided with an insertion part 106 at one end near the middle sleeve 200. The insertion part 106 is inserted into the rod body assembly cavity 2015 of the middle sleeve 200 and is detachably assembled with the middle sleeve 200. The insertion part 106 and the rod body assembly cavity 2015 of the middle sleeve 200 are generally engaged by a snap-fit.

[0126] In this device, the inlet of the detection channel 105 is in close contact with the outlet of the liquid channel, and the sample injection end of the test strip 103 is close to the inlet of the detection channel 105. The sample injection end of the test strip 103 should be as close as possible to the inlet of the detection channel 105 to reduce the flow distance of the sampling liquid, so that after the sampling liquid enters the stick body 100, it wets the test strip 103 and is loaded with the sample through the shortest distance.

[0127] In a preferred embodiment, the length of the insertion portion 106 of the rod body 100 is adapted to the depth of the rod body assembly cavity 2015, and the guide rod body 3012 in the middle sleeve 200 is in close contact with the insertion portion 106 of the rod body 100 inserted into the rod body assembly cavity 2015.

[0128] Figure 8 The instructions for using the integrated dual-headed rod-sleeve sampling and testing device are shown.

[0129] Figure A shows step 1, during sampling, where the sampling column 304 is removed from the first cavity 4011 to collect biological liquid samples.

[0130] Figure B shows step 2, where the sampling column 304 is inserted into the sampling cavity 4041.

[0131] Figure C shows step 3: the sampling column 304 pierces the sealing film 403 and enters the liquid storage chamber 4012. The sample collected on the sampling column 304 is released into the liquid reagent in the liquid storage chamber 4012 and mixed to obtain the sampling liquid. The sampling liquid is squeezed out of the liquid storage chamber 4012 by the sampling column 304. At this time, a seal is formed between the liquid guiding part 202 and the sampling chamber 4041, and the space of the sampling chamber 4041 is occupied by the liquid guiding part 202. The liquid holding space becomes smaller, and the liquid is guided into the liquid channel of the sampling rod 300. The liquid level rises and enters the rod body assembly cavity 2015. It enters the rod body 100 from the detection channel 105 entrance and is sampled at the injection end of the test strip 103. The test result is read from the transparent window 102.

Claims

1. A dual-headed rod-sleeve sampling and detection integrated device, characterized in that... The device includes a sampling probe and a double-ended probe sleeve. The sampling probe comprises a detachable probe body, a middle sleeve, and a sampling probe, all assembled as a single unit. The double-ended probe sleeve includes a first cavity and a second cavity that are not interconnected. Both the first cavity and the second cavity are hollow cylinders with one open end and the other closed. The sampling probe includes a sampling column for sampling, which is detachably inserted into the first cavity. The second cavity consists of a sealed liquid storage cavity and a sampling cavity with one open end. The liquid storage cavity and the sampling cavity are sealed by a sealing film. The sealing film can be pierced by the sampling column, allowing the sampling column to be inserted into the liquid storage cavity. The liquid storage cavity is filled with liquid reagent. The sampling probe has a liquid channel. The middle sleeve has a connected liquid guiding channel and a probe body assembly cavity. The liquid channel and the liquid guiding channel are connected, and the probe body is inserted into the probe body assembly cavity. The probe body has a detection channel containing a test strip. The probe body has a transparent window for displaying the test strip's detection result. The entrance of the detection channel is connected to the probe body assembly cavity of the middle sleeve.

2. The integrated sampling and detection device with double-headed rod sleeve as described in claim 1, characterized in that... The length of the sampling column is matched with the depth of the liquid storage chamber, and the outer diameter of the sampling column is matched with the inner diameter of the liquid storage chamber. When the sampling column is inserted into the liquid storage chamber, the liquid reagent is squeezed out and enters the liquid channel of the sampling rod.

3. The integrated sampling and detection device with double-headed rod sleeve as described in claim 1, characterized in that... The middle sleeve consists of a liquid guiding part and an assembly part, both of which are hollow cylinders. The liquid guiding part has a liquid guiding channel with openings at both ends, and the assembly part has a rod body assembly cavity with openings at both ends; the liquid guiding channel and the rod body assembly cavity are interconnected. The liquid guiding section and the sampling rod are detachably assembled, and the assembly section and the rod body are detachably assembled; after assembly, the sampling column is located at the front end of the liquid guiding section. The liquid guiding part is clearance-fitted with the first cavity or sampling cavity, and the first cavity or sampling cavity is sealed by a middle sleeve sealing ring provided on the outer wall of the liquid guiding part.

4. The integrated sampling and detection device with double-headed rod sleeve as described in claim 3, characterized in that... The liquid guiding part is provided with a connecting part at its end. The connecting part is a column at the end of the liquid guiding part facing the opening of the sampling rod. On the end face of the connecting part, at least one recessed liquid inlet groove is distributed circumferentially. The liquid inlet groove penetrates the end face of the connecting part radially, and one end of the liquid inlet groove is connected to the liquid guiding channel in the liquid guiding part, and the other end is connected to the first cavity or the second cavity.

5. The integrated sampling and detection device with double-headed rod sleeve as described in claim 4, characterized in that... The sampling rod includes a sampling part and a sampling rod body. One end of the sampling rod body is a sampling column body, and the other end is a flow guide rod body. The sampling part is located on the sampling column body to form the sampling column. The flow guide rod body is inserted into the liquid guiding channel of the middle sleeve and is detachably assembled with the liquid guiding part of the middle sleeve. The sampling rod body is a solid column or a hollow column. When the sampling rod body is a solid column, the sampling part is located on the outer layer of the sampling column body. The guide rod body is provided with at least one recessed guide groove along the axial direction as a liquid channel. The inlet of the guide groove is connected to the liquid inlet groove at the end of the middle sleeve, and the outlet of the guide groove is close to the inlet of the detection channel. When the sampling rod is a hollow cylinder, the inside of the sampling rod has a hollow inner core channel that runs through the sampling rod, which is a liquid channel; one end of the inner core channel has a sampling part, and the head of the sampling part protrudes from the opening of the inner core channel; the outlet at the other end is close to the inlet of the detection channel; the sampling part is made of porous material.

6. The integrated sampling and detection device with double-headed rod sleeve as described in claim 5, characterized in that... When the sampling rod is a solid column, the sampling part is located on the outer layer of the sampling column. The sampling part is made of an elastic porous material. The inner diameter of the liquid storage cavity is larger than the diameter of the sampling column, but slightly smaller than the total diameter of the sampling column and the sampling part, so that when the sampling rod is inserted into the liquid storage cavity, the sampling part is squeezed by the inner wall of the liquid storage cavity.

7. The integrated sampling and detection device with double-headed rod sleeve as described in claim 5, characterized in that... The guide rod body and the liquid guiding channel of the middle sleeve can be detachably assembled through a snap-fit ​​structure, and the guide rod body and the liquid guiding channel are fitted with a clearance.

8. The integrated sampling and detection device with double-headed rod sleeve as described in claim 1, characterized in that... The double-ended rod sleeve includes a detachably fitted first rod head and a second rod head. One end of the first rod head has an open first cavity, and the other end has a sealed liquid storage cavity. The first cavity and the liquid storage cavity are not in communication. The open end of the first cavity and the sealing film are located at the two ends of the first rod head, respectively. The second rod head is a hollow cavity with open ends. One end is a sampling cavity, and the other end is an assembly cavity. The liquid storage cavity of the first rod head is inserted into the assembly cavity of the second rod head and is detachably fitted with the second rod head. The outer wall of the liquid storage cavity is provided with a detachable rod sleeve sealing ring for sealing the outer wall of the liquid storage cavity and the assembly cavity.

9. The integrated sampling and detection device with double-headed rod sleeve as described in claim 1, characterized in that... The rod body is composed of an upper plate and a lower plate that are snapped together. A hollow detection channel with one open end is provided between the upper plate and the lower plate. The detection channel is used to place the test strip. The entrance of the detection channel is connected to the rod body assembly cavity of the middle sleeve. The upper plate is equipped with a transparent window for displaying the test strip results; The rod body has an insertion part at one end near the middle sleeve, and the insertion part can be detachably assembled with the rod body assembly cavity of the middle sleeve.

10. The integrated sampling and detection device with double-headed rod sleeve as described in claim 1, characterized in that... The inlet of the detection channel is close to the outlet of the liquid channel, and the sample injection end of the test strip is close to the inlet of the detection channel.

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