2-acetoxy-N-(4-chlorphenyl) benzamide as well as preparation method and application of 2-acetoxy-N-(4-chlorphenyl) benzamide

Abstract

The invention relates to 2-acetoxy-N-(4-chlorphenyl) benzamide as well as a preparation method and application of 2-acetoxy-N-(4-chlorphenyl) benzamide, belonging to the field of pesticides. The invention aims to solve the technical problem that a compound which can kill or inhibit pathogenic bacteria of crops is provided. The structural formula of the compound is shown in a formula (I) in the specification.

Description

technical field

[0001] The invention relates to 2-acetoxy-N-(4-chlorophenyl)benzamide, a preparation method and application thereof, and belongs to the field of pesticides. Background technique

[0002] Pesticide is a general term for chemical agents used to prevent and control pests, weeds and other harmful organisms that harm crops and agricultural by-products. It is closely related to agriculture and animal husbandry, and is also closely related to people's lives. Therefore, people have known for a long time to utilize pesticides to prevent and control the pests and diseases of crops. More than 1000 BC, in ancient Greece, there were records of using sulfur to fumigate pests and prevent diseases. In the 5th to 7th centuries BC, my country also began to use mangcao, mirage ash, and oyster to kill pests. At first, the pesticides used by people were mainly derived from natural plants. Some parts of plants were used or their active ingredients were extracted to make pesticid...

Examples

Embodiment 1

[0029] Example 1 Preparation of 2-acetoxy-N-(4-chlorophenyl)benzamide

[0030] Dissolve 4-chloroaniline (30mmol) and o-acetoxybenzoyl chloride (30mmol) in 10mL of dichloromethane respectively, put the dissolved 4-chloroaniline into a three-necked flask, and then add pyridine (30mmol) , put it in a constant temperature water bath at 30°C, then slowly drop the dissolved o-acetoxybenzoyl chloride into the three-necked bottle, stir at constant temperature for 3-4 hours, and take out 10% hydrochloric acid that is twice the volume of the reaction solution Elute 2-3 times, place in a refrigerator at 2-6°C until a solid precipitates, filter, wash, and recrystallize with absolute ethanol until the pure substance is obtained.

[0031] The structural identification of prepared 2-acetoxy-N-(4-chlorophenyl)benzamide is as follows:

[0032] through IR, 1 The structure was confirmed by H NMR, and the results were analyzed as follows:

[0033] 2-Acetoxy-N-(4-chlorophenyl)benzamide (C 15 h...

technical field

[0001] The invention relates to 2-acetoxy-N-(4-chlorophenyl)benzamide, a preparation method and application thereof, and belongs to the field of pesticides. Background technique

[0002] Pesticide is a general term for chemical agents used to prevent and control pests, weeds and other harmful organisms that harm crops and agricultural by-products. It is closely related to agriculture and animal husbandry, and is also closely related to people's lives. Therefore, people have known for a long time to utilize pesticides to prevent and control the pests and diseases of crops. More than 1000 BC, in ancient Greece, there were records of using sulfur to fumigate pests and prevent diseases. In the 5th to 7th centuries BC, my country also began to use mangcao, mirage ash, and oyster to kill pests. At first, the pesticides used by people were mainly derived from natural plants. Some parts of plants were used or their active ingredients were extracted to make pesticid...

Examples

Embodiment 1

[0029] Example 1 Preparation of 2-acetoxy-N-(4-chlorophenyl)benzamide

[0030] Dissolve 4-chloroaniline (30mmol) and o-acetoxybenzoyl chloride (30mmol) in 10mL of dichloromethane respectively, put the dissolved 4-chloroaniline into a three-necked flask, and then add pyridine (30mmol) , put it in a constant temperature water bath at 30°C, then slowly drop the dissolved o-acetoxybenzoyl chloride into the three-necked bottle, stir at constant temperature for 3-4 hours, and take out 10% hydrochloric acid that is twice the volume of the reaction solution Elute 2-3 times, place in a refrigerator at 2-6°C until a solid precipitates, filter, wash, and recrystallize with absolute ethanol until the pure substance is obtained.

[0031] The structural identification of prepared 2-acetoxy-N-(4-chlorophenyl)benzamide is as follows:

[0032] through IR, 1 The structure was confirmed by H NMR, and the results were analyzed as follows:

[0033] 2-Acetoxy-N-(4-chlorophenyl)benzamide (C 15 h...

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