A kind of pharmaceutical composition for rhinitis and preparation method thereof

Abstract

The invention provides a pharmaceutical composition for treating rhinitis. A preparation method of the pharmaceutical composition comprises the steps that Jiejiehonghua, watermelon pedicle, pseudosciaena crocea, centipeda minima, magnolia flower and cordate houttuynia are decocted with water for extraction and concentrated into paste, radix angelicae is ground into powder to be mixed with the extract paste. The pharmaceutical composition is safe in ingredient, becomes effective rapidly and has the excellent effect. The invention further provides the preparation method of the pharmaceutical composition for treating rhinitis. The method is easy and convenient to implement and good in repeatability. The invention further provides application of the pharmaceutical composition in treating rhinitis such as allergic rhinitis, hypertrophic rhinitis, simple rhinitis and nasosinusitis. The pharmaceutical composition is multifunctional and has the good treatment effect on various types of rhinitis caused by various etiological factors.

Description

technical field

[0001] The invention relates to the field of pharmacy, in particular to a pharmaceutical composition for rhinitis and a preparation method thereof. Background technique

[0002] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of nasal mucosa. Rhinitis brings a lot of inconvenience to people's life. Its symptoms are various, which can lead to nasal congestion, nasal itching, sneezing, runny nose, and severe cases can even lead to loss of nasal sensation, dizziness, insomnia, and then lead to memory loss and a serious decline in quality of life. .

[0003] For the treatment of rhinitis, there is no radical cure in the prior art, and generally there are several methods of treatment and re...

Examples

Embodiment 1

[0033] Prepare the ointment of the present invention according to the following steps:

[0034] 1) Take the following raw materials for use, by weight, 0.8 parts of safflower, 0.8 parts of watermelon stalks, 0.8 parts of fish brain stones, 100 parts of goose not eating grass, 100 parts of magnolia and 1.2 parts of Houttuynia cordata;

[0035] 2) Under normal temperature conditions, decoct the above-mentioned medicinal materials with water, the weight ratio of water and medicinal materials used is 3:1, decoct twice, each time for 0.5h, extract the filtrate and concentrate it to a density of 1.10g / cm 3 the paste;

[0036] 3) Grinding Angelica dahurica into 120-mesh fine powder, mixing and mixing the above paste, wherein the weight ratio of paste to Angelica powder is 6:4.

Embodiment 2

[0038] 1) Take the following raw materials for use, by weight, 1.2 parts of safflower, 1.2 parts of watermelon stalks, 1.2 parts of fish brain stones, 0.8 parts of goose not eating grass, 0.8 parts of magnolia and 1.0 parts of Houttuynia cordata;

[0039] 2) Under normal temperature conditions, decoct the above-mentioned medicinal materials with water, the weight ratio of water and medicinal materials used is 3:1, decoct in water 4 times, each time for 1 hour, extract the filtrate and concentrate it to a density of 1.50g / cm 3 the paste;

[0040] 3) Grinding Angelica dahurica into fine powder, mixing and mixing the above paste, wherein the weight ratio of paste to Angelica powder is 7:3.

[0041] 4) Add 0.12% paraben by the total weight of the above ointment, and mix well.

Embodiment 3

[0043] 1) Take the following raw materials for use, by weight, 1.0 parts of safflower, 1.0 parts of watermelon stalks, 1.0 parts of fish brain stones, 1.2 parts of goose not eating grass, 1.2 parts of magnolia and 1.2 parts of Houttuynia cordata;

[0044] 2) Under normal temperature conditions, decoct the above-mentioned medicinal materials with water, the weight ratio of water and medicinal materials used is 3:1, decoct in water for 3 times, each time for 1.5 hours, extract the filtrate and condense it into a paste with a density of 1.35;

[0045] 3) Grinding Angelica dahurica into fine powder, mixing and mixing the above paste, wherein the weight ratio of paste to Angelica powder is 8:2.

[0046] 4) Add 0.20% paraben by the total weight of the above ointment, and mix well.

technical field

[0001] The invention relates to the field of pharmacy, in particular to a pharmaceutical composition for rhinitis and a preparation method thereof. Background technique

[0002] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of nasal mucosa. Rhinitis brings a lot of inconvenience to people's life. Its symptoms are various, which can lead to nasal congestion, nasal itching, sneezing, runny nose, and severe cases can even lead to loss of nasal sensation, dizziness, insomnia, and then lead to memory loss and a serious decline in quality of life. .

[0003] For the treatment of rhinitis, there is no radical cure in the prior art, and generally there are several methods of treatment and re...

Examples

Embodiment 1

[0033] Prepare the ointment of the present invention according to the following steps:

[0034] 1) Take the following raw materials for use, by weight, 0.8 parts of safflower, 0.8 parts of watermelon stalks, 0.8 parts of fish brain stones, 100 parts of goose not eating grass, 100 parts of magnolia and 1.2 parts of Houttuynia cordata;

[0035] 2) Under normal temperature conditions, decoct the above-mentioned medicinal materials with water, the weight ratio of water and medicinal materials used is 3:1, decoct twice, each time for 0.5h, extract the filtrate and concentrate it to a density of 1.10g / cm 3 the paste;

[0036] 3) Grinding Angelica dahurica into 120-mesh fine powder, mixing and mixing the above paste, wherein the weight ratio of paste to Angelica powder is 6:4.

Embodiment 2

[0038] 1) Take the following raw materials for use, by weight, 1.2 parts of safflower, 1.2 parts of watermelon stalks, 1.2 parts of fish brain stones, 0.8 parts of goose not eating grass, 0.8 parts of magnolia and 1.0 parts of Houttuynia cordata;

[0039] 2) Under normal temperature conditions, decoct the above-mentioned medicinal materials with water, the weight ratio of water and medicinal materials used is 3:1, decoct in water 4 times, each time for 1 hour, extract the filtrate and concentrate it to a density of 1.50g / cm 3 the paste;

[0040] 3) Grinding Angelica dahurica into fine powder, mixing and mixing the above paste, wherein the weight ratio of paste to Angelica powder is 7:3.

[0041] 4) Add 0.12% paraben by the total weight of the above ointment, and mix well.

Embodiment 3

[0043] 1) Take the following raw materials for use, by weight, 1.0 parts of safflower, 1.0 parts of watermelon stalks, 1.0 parts of fish brain stones, 1.2 parts of goose not eating grass, 1.2 parts of magnolia and 1.2 parts of Houttuynia cordata;

[0044] 2) Under normal temperature conditions, decoct the above-mentioned medicinal materials with water, the weight ratio of water and medicinal materials used is 3:1, decoct in water for 3 times, each time for 1.5 hours, extract the filtrate and condense it into a paste with a density of 1.35;

[0045] 3) Grinding Angelica dahurica into fine powder, mixing and mixing the above paste, wherein the weight ratio of paste to Angelica powder is 8:2.

[0046] 4) Add 0.20% paraben by the total weight of the above ointment, and mix well.

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