Deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives and preparation method of mouth wash

Abstract

The invention discloses a deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives. The mouth wash is prepared from, by weight, 3% of chitosan derivatives, 5% of glycerol, 1.5% of xylitol, 2% of efficient solubilizer, 0.55% of citric acid, 0.3% of sodium citrate, 0.25% of malic acid, 0.12% of menthol, 0.15% of mint fragrance, 2% of propolis extracts, 3.5% of tea leaf extracts, 0.07% of caramel colour, 0.04% of saccharin sodium, 0.2% of chlorhexidine, 0.0003% of domiphen bromide and the balance deionized water. The invention provides the deep-cleaning, antibacterial and tooth-protecting mouth wash based on the chitosan derivatives and the preparation method of the mouth wash. The mouth wash prepared through the method has the functions of inhibiting bacteria, removing dental plaque and preventing oral ulcer, gingivitis and other oral diseases, and is good in antibacterial effect, quick in effect, free of toxic and side effects and comfortable in mouthfeel.

Description

technical field

[0001] The invention relates to the technical field of oral care, in particular to a mouthwash based on chitosan derivatives for deep cleaning and antibacterial tooth protection and a preparation method thereof. Background technique

[0002] With the development of economy and society and the improvement of people's living standards, people's dietary structure is also changing, and corresponding oral diseases are becoming more and more common. At present, the incidence of oral diseases is extremely high, and the prevention and treatment of oral diseases And tooth protection is particularly important. The pathological phenomenon of the oral cavity in the event of damage by external physical and chemical factors, invasion of pathogens, abnormal dental and maxillofacial development, and systemic diseases. There are many types of oral diseases, which originate in the oral cavity. Oral inflammatory diseases, such as oral ulcers, pharyngitis, laryngitis, tonsilli...

Examples

Embodiment 1

[0027] Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 2%, glycerin 5%, xylitol 1%, high-efficiency solubilizer 1.5% , citric acid 0.5%, sodium citrate 0.1%, malic acid 0.1%, menthol 0.1%, mint flavor 0.1%, propolis extract 1%, tea extract 2%, caramel color 0.01%, saccharin sodium 0.01%, washing Bitai 0.1%, Domifene 0.0001%, and deionized water as the balance.

[0028] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0029] Further, the high-efficiency solubilizer is C0-40.

[0030] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0031] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0032] (2) Heat deionized water to 90°C and...

Embodiment 2

[0040]Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 3%, glycerin 5%, xylitol 1.5%, high-efficiency solubilizer 2% , citric acid 0.55%, sodium citrate 0.3%, malic acid 0.25%, menthol 0.12%, mint flavor 0.15%, propolis extract 2%, tea extract 3.5%, caramel color 0.07%, saccharin sodium 0.04%, washing Bitai 0.2%, Domifene 0.0003%, and deionized water as the balance.

[0041] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0042] Further, the high-efficiency solubilizer is C0-40.

[0043] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0044] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0045] (2) Heat the deionized water to...

Embodiment 3

[0053] Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 5%, glycerin 6%, xylitol 3%, high-efficiency solubilizer 3% , citric acid 1%, sodium citrate 0.5%, malic acid 0.3%, menthol 0.2%, mint flavor 0.2%, propolis extract 3%, tea extract 4%, caramel color 0.1%, saccharin sodium 0.05%, washing Bitai 0.3%, Domiphene 0.0003%, and deionized water as the balance.

[0054] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0055] Further, the high-efficiency solubilizer is C0-40.

[0056] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0057] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0058] (2) Heat the deionized water to 90°C and...

technical field

[0001] The invention relates to the technical field of oral care, in particular to a mouthwash based on chitosan derivatives for deep cleaning and antibacterial tooth protection and a preparation method thereof. Background technique

[0002] With the development of economy and society and the improvement of people's living standards, people's dietary structure is also changing, and corresponding oral diseases are becoming more and more common. At present, the incidence of oral diseases is extremely high, and the prevention and treatment of oral diseases And tooth protection is particularly important. The pathological phenomenon of the oral cavity in the event of damage by external physical and chemical factors, invasion of pathogens, abnormal dental and maxillofacial development, and systemic diseases. There are many types of oral diseases, which originate in the oral cavity. Oral inflammatory diseases, such as oral ulcers, pharyngitis, laryngitis, tonsilli...

Examples

Embodiment 1

[0027] Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 2%, glycerin 5%, xylitol 1%, high-efficiency solubilizer 1.5% , citric acid 0.5%, sodium citrate 0.1%, malic acid 0.1%, menthol 0.1%, mint flavor 0.1%, propolis extract 1%, tea extract 2%, caramel color 0.01%, saccharin sodium 0.01%, washing Bitai 0.1%, Domifene 0.0001%, and deionized water as the balance.

[0028] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0029] Further, the high-efficiency solubilizer is C0-40.

[0030] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0031] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0032] (2) Heat deionized water to 90°C and...

Embodiment 2

[0040]Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 3%, glycerin 5%, xylitol 1.5%, high-efficiency solubilizer 2% , citric acid 0.55%, sodium citrate 0.3%, malic acid 0.25%, menthol 0.12%, mint flavor 0.15%, propolis extract 2%, tea extract 3.5%, caramel color 0.07%, saccharin sodium 0.04%, washing Bitai 0.2%, Domifene 0.0003%, and deionized water as the balance.

[0041] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0042] Further, the high-efficiency solubilizer is C0-40.

[0043] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0044] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0045] (2) Heat the deionized water to...

Embodiment 3

[0053] Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 5%, glycerin 6%, xylitol 3%, high-efficiency solubilizer 3% , citric acid 1%, sodium citrate 0.5%, malic acid 0.3%, menthol 0.2%, mint flavor 0.2%, propolis extract 3%, tea extract 4%, caramel color 0.1%, saccharin sodium 0.05%, washing Bitai 0.3%, Domiphene 0.0003%, and deionized water as the balance.

[0054] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0055] Further, the high-efficiency solubilizer is C0-40.

[0056] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0057] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0058] (2) Heat the deionized water to 90°C and...