A spotting machine

Abstract

The present invention discloses a sample dispenser with accurate, stable and uniform sample addition, and belongs to the technical field of in vitro diagnostic equipment. The sample dispenser of the present invention comprises a mainframe, a conveying device located on the mainframe, a sample addition platform located on the conveying device, a sample addition device located on the sample addition platform, a metering pump tower connected to the sample addition device through a pipeline, and a control device electrically connected to the mainframe, the conveying device, the sample addition device and the metering pump tower respectively, wherein the sample addition device comprises a liquid adding seat, a motor located above the liquid adding seat, an output shaft fixed to the lower part of the motor, a stirring seat fixed below the liquid adding seat, a stirring brush head placed on the stirring seat, and a sample addition needle passing through the center of the liquid adding seat and the stirring brush head in sequence, the liquid adding seat has a through hole, and the output shaft passes through the through hole and is transmission-connected to the stirring brush head. The sample dispenser provided by the present invention can complete multiple operations such as liquid injection, coating, reflux and cleaning, which is convenient, fast, time-saving and labor-saving, and meets the needs of accurate, stable and uniform sample addition.

Description

Technical Field

[0001] The present invention relates to the technical field of in vitro diagnostic equipment, and in particular to a spotting machine. Background Art

[0002] At present, when using in vitro diagnostic kits or reagent cards for detection and analysis, or when coating the kit, it is often necessary to add additional liquid for dilution, mixing and other operations. These operations are not only cumbersome and time-consuming, but also due to the instability of the operating techniques, the added liquid is very easy to overflow or uneven, or the added liquid has a large surface tension, resulting in thicker droplets, which in turn affects the detection speed and result interpretation. Summary of the invention

[0003] The present invention aims at the technical problems of easy overflow or unevenness or thick droplets in the sample adding process, and provides a spotting machine, wherein the sample adding device of the spotting machine can accurately control the sample adding position and sample adding amount, and the sample adding is uniform.

[0004] In order to achieve the above object, the present invention provides the following technical solutions:

[0005] A sample dispenser includes a main machine, a conveying device located on the main machine, a sample loading platform located on the conveying device, a sample loading device located on the sample loading platform, a metering pump tower connected to the sample loading device through a pipeline, and a control device electrically connected to the main machine, the conveying device, the sample loading device and the metering pump tower respectively, wherein the sample loading device includes a liquid adding seat, a motor located above the liquid adding seat, a stirring seat fixed below the liquid adding seat, a stirring brush head placed on the stirring seat, and a sample loading needle passing through the center of the liquid adding seat and the stirring brush head in sequence, an output shaft is formed at the output end of the motor, the liquid adding seat has a through hole, the output shaft passes through the through hole, and is connected to the stirring brush head through a transmission assembly. Depending on the amount of objects to be tested, multiple sample loading needles can also be arranged side by side.

[0006] Furthermore, the transmission assembly is located below the liquid adding seat and includes a driving gear, a first driven gear, and a second driven gear fixed above the stirring brush head; the driving gear has a driving gear shaft, and the first driven gear has a driven gear shaft; the driving gear is connected to the output shaft by meshing with the output shaft, the first driven gear is connected to the driving gear by meshing with the driving gear shaft, and the second driven gear is connected to the first driven gear by meshing with the driven gear shaft, thereby realizing the transmission connection between the output shaft and the stirring brush head. When the sample adding device has multiple sample adding needles, multiple stirring brush heads and second driven gears are added accordingly. Each second driven gear is connected to the output shaft and the stirring brush head by meshing with each other.

[0007] Furthermore, the diameter of the driving gear is smaller than that of the first driven gear, and the diameter of the first driven gear is smaller than that of the second driven gear. By utilizing the principle of the reducer, the rotation speed of the second driven gear is lower than that of the output shaft by increasing the gear diameters in sequence, thereby reducing the rotation speed of the stirring brush head, making the sample addition more uniform and preventing overflow.

[0008] Furthermore, the stirring seat has at least one stirring groove, and each stirring groove can accommodate a stirring brush head. When the sample adding device has multiple sample adding needles, each sample adding needle is provided with a stirring brush head and a second driven gear, and is located in a stirring groove. The stirring groove not only plays a bearing role, but also plays a role of isolating each sample adding needle, thereby avoiding cross contamination between samples.

[0009] Furthermore, a motor slot is provided above the liquid adding seat, and the motor is located in the motor slot and is sealed by a cover plate to prevent the motor from being invaded by dust and the like.

[0010] Furthermore, the conveying device has a conveying track for conveying the object to be tested to the sample loading platform. In the horizontal and vertical directions of the conveying track, both sides of the conveying device are also provided with limiting grooves for fixing the object to be tested so that it can be stably transported on the conveying track.

[0011] Furthermore, the spotting machine further includes a liquid storage device, the liquid storage device and the metering pump tower are connected by a pipeline, and the liquid in the liquid storage device is injected into the sample adding device by controlling the flow rate through the metering pump tower. The liquid storage device and the metering pump tower can be set to multiple according to the type and amount of sample to be added, and the sample can be added at the same time, which can save time and avoid cross contamination.

[0012] Furthermore, the sample loading platform is fixedly provided with a detection device, which is electrically connected to the control device and performs real-time detection on the object to be tested transported to the sample loading platform by the conveying device.

[0013] Furthermore, the detection device is an infrared sensing device. When the conveying device transports the object to be tested to under the sample loading platform, the infrared sensing device detects the arrival of the object to be tested, and the control device then starts the sample loading device to load the sample.

[0014] Furthermore, the control device has a display device for displaying and viewing the detection information, and the display device has a touch screen for human-computer information interaction.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] The present invention provides a sample loading device on the sample loading table, which can accurately control the sample loading position and sample loading amount, thereby solving the problem that the added liquid is very easy to overflow or be uneven due to the instability of the sample loading operation during the coating or detection sample loading process. The sample loading device has a stirring brush head, which controls the output shaft to rotate through a motor and then drives the stirring brush head to rotate to spread the added sample evenly, thereby solving the problem that the added liquid has thick droplets due to the large surface tension, thereby affecting the detection speed and result interpretation.

[0017] The spotting machine of the present invention can be provided with a plurality of sample adding needles and stirring brush heads according to the amount and type of sample to be added, and can complete multiple operations such as liquid injection, coating, reflux and cleaning, etc. It is convenient, fast, time-saving and labor-saving, allowing the operator to use it calmly, and its high efficiency helps customers save production costs, reduce operation links, and improve existing production capacity. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0019] Figure 1 A schematic diagram of the structure of a spotting machine provided by an embodiment of the present invention;

[0020] Figure 2 A schematic diagram of the structure of the sample adding device provided in the embodiment of the present invention Figure 1 ;

[0021] Figure 3 A schematic diagram of the structure of the sample adding device provided in the embodiment of the present invention Figure 2 ;

[0022] Figure 4 The structure explosion of the sample adding device provided by the embodiment of the present invention Figure 1 ;

[0023] Figure 5 The structure explosion of the sample adding device provided by the embodiment of the present invention Figure 2 ;

[0024] Figure 6 A schematic diagram of the structure of the transmission assembly provided in the embodiment of the present invention Figure 1 ;

[0025] Figure 7 A schematic diagram of the structure of the transmission assembly provided in the embodiment of the present invention Figure 2 .

[0026] Description of reference numerals:

[0027] 1. Main machine; 2. Conveying device; 21. Conveying track; 22. Limiting groove; 3. Sample adding platform; 4. Sample adding device; 41. Liquid adding seat; 411. Through hole; 412. Motor slot; 413. Cover plate; 42. Motor; 43. Output shaft; 44. Stirring seat; 441. Stirring groove; 45. Stirring brush head; 46. Sample adding needle; 47. Driving gear; 471. Driving gear shaft; 48. First driven gear; 481. Driven gear shaft; 49. Second driven gear; 5. Metering pump tower; 6. Control device; 7. Liquid storage device; 8. Detection device; 9. Display device; 91. Touch screen. DETAILED DESCRIPTION

[0028] In order to make those skilled in the art better understand the technical solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings. The object to be detected can be a detection card, such as a blood type card.

[0029] See also Figure 1 to Figure 7 As shown;

[0030] A spotting machine of the present invention comprises a main machine 1, a conveying device 2 located on the main machine 1, a sample loading platform 3 located on the conveying device 2, a sample loading device 4 located on the sample loading platform 3, a metering pump tower 5 connected to the sample loading device 4 through a pipeline, and a control device 6 electrically connected to the main machine 1, the conveying device 2, the sample loading device 4 and the metering pump tower 5, respectively, wherein the sample loading device 4 comprises a liquid loading seat 41, a motor 42 located above the liquid loading seat 41, a stirring seat 44 fixed below the liquid loading seat 41, a stirring brush head 45 placed on the stirring seat 44, and a sample loading needle 46 passing through the center of the liquid loading seat 41 and the stirring brush head 45 in sequence, an output shaft 43 is formed at the output end of the motor 42, the liquid loading seat 41 has a through hole 411, the output shaft 43 passes through the through hole 411, and is connected to the stirring brush head 45 through a transmission assembly. According to the amount of the objects to be tested, a plurality of sample loading needles can also be arranged side by side. The stirring brush head 45 may be two symmetrically arranged vertical plates 451. After the liquid is injected into the test object through the sample injection needle 3, the two vertical plates 451 can evenly spread the liquid as the stirring brush head 45 rotates. The stirring brush head 45 may also be one or more vertical plates 451 according to the use requirements.

[0031] Preferably, the transmission assembly is located below the liquid adding seat 41, and includes a driving gear 47, a first driven gear 48, and a second driven gear 49 fixed above the stirring brush head 45; the driving gear 47 has a driving gear shaft 471, and the first driven gear 48 has a driven gear shaft 481; the driving gear 47 realizes a transmission connection with the output shaft 43 by meshing with the output shaft 43, the first driven gear 48 realizes a transmission connection with the driving gear 47 by meshing with the driving gear shaft 471, and the second driven gear 49 realizes a transmission connection with the first driven gear 48 by meshing with the driven gear shaft 481, thereby realizing a transmission connection between the output shaft 43 and the stirring brush head 45. According to the number of the adding needles 3, multiple second driven gears 49 and the stirring brush head 45 can be provided, and each second driven gear 49 meshes with each other to realize a transmission link.

[0032] Preferably, the diameter of the driving gear 47 is smaller than the diameter of the first driven gear 48, and the diameter of the first driven gear 48 is smaller than the diameter of the second driven gear 49. By utilizing the principle of the reducer, the rotation speed of the second driven gear 49 is lower than the rotation speed of the output shaft 43 by increasing the gear diameters in sequence, thereby reducing the rotation speed of the stirring brush head 45, so that the sample addition is more uniform and does not overflow.

[0033] Preferably, the stirring seat 44 has four stirring grooves 441, and each stirring groove 441 can accommodate a stirring brush head 45. When the sample adding device 4 has multiple sample adding needles 3, each sample adding needle 3 is provided with a stirring brush head 45 and a second driven gear 49, and is located in a stirring groove 441. The stirring groove 441 not only plays a bearing role, but also plays a role of isolating each sample adding needle 3, thereby avoiding cross contamination between samples.

[0034] Preferably, a motor slot 412 is provided above the liquid adding seat 41, and the motor 42 is located in the motor slot 412 and sealed by a cover plate 413. The cover plate 413 and the motor slot 412 can be sealed by pulling, or can be movably connected by hinges, or can be fixedly connected by bolts, which can effectively prevent the motor 42 from being invaded by dust, etc.

[0035] Preferably, the conveying device 2 has a conveying track 21 for conveying the object to be tested to the sample loading table 3. In the horizontal and vertical directions of the conveying track 21, limiting grooves 22 are also provided on both sides of the conveying device 2 for fixing the object to be tested so that it is transported on the conveying track 21, thereby ensuring the stability of transportation.

[0036] Preferably, the spotting machine further comprises a liquid storage device 7, wherein the liquid storage device 7 and the metering pump tower 5 are connected by a pipeline, and the liquid in the liquid storage device 7 is injected into the sample adding device 4 by controlling the flow rate through the metering pump tower 5. The liquid storage device 7 and the metering pump tower 5 can be set to multiple according to the type and amount of sample to be added, and adding samples at the same time can save time and avoid cross contamination.

[0037] Preferably, the sample loading platform 3 is fixedly provided with a detection device 8 , which is electrically connected to the control device 6 and performs real-time detection on the object to be tested transported to the sample loading platform 3 by the conveying device 2 .

[0038] Preferably, the detection device 8 is an infrared sensing device. When the conveying device 2 transports the object to be tested to under the sample loading platform 3, the infrared sensing device detects the arrival of the object to be tested, and the control device 6 then starts the sample loading device 4 to load the sample.

[0039] Preferably, the control device 6 has a display device 9 for displaying and viewing the detection information, and the display device has a touch screen 91 for human-computer information interaction. For example, by selecting the "liquid injection" mode through the touch screen 91, the instrument can fill the pipeline cavity with liquid before working; by selecting the "coating" mode through the touch screen 91, the instrument enters the coating mode; by selecting the "reflux" mode through the touch screen 91, the instrument can empty the liquid in the pipeline cavity after the work is completed; by selecting the "cleaning" mode through the touch screen 91, the instrument can regularly clean the liquid filling seat and pipelines.

[0040] In the above technical scheme, the spotting machine provided by the present invention is provided with a loading device on the loading table, which can accurately control the loading position and loading amount, thereby solving the problem that the added liquid is very easy to overflow or be uneven due to the instability of the loading operation during the coating or detection loading process. The loading device has a stirring brush head, which controls the output shaft to rotate through a motor and then drives the stirring brush head to rotate so that the added sample is evenly spread, thereby solving the problem that the added liquid has thicker droplets due to the large surface tension, thereby affecting the detection speed and result interpretation.

[0041] The spotting machine of the present invention can complete multiple operations such as injection, coating, reflow and cleaning, which is convenient, fast, time-saving and labor-saving, allowing operators to use it calmly. Its high efficiency helps customers save production costs, reduce operation links, and improve existing production capacity.

[0042] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A spotting machine, comprising a main machine (1), a conveying device (2) located on the main machine (1), a sample loading platform (3) located on the conveying device (2), a sample loading device (4) located on the sample loading platform (3), a metering pump tower (5) connected to the sample loading device (4) through a pipeline, and a control device (6) electrically connected to the main machine (1), the conveying device (2), the sample loading device (4) and the metering pump tower (5), characterized in that: The sample adding device (4) comprises a liquid adding seat (41), a motor (42) located above the liquid adding seat (41), a stirring seat (44) fixed below the liquid adding seat (41), a stirring brush head (45) placed on the stirring seat (44), and a sample adding needle (46) passing through the center of the liquid adding seat (41) and the stirring brush head (45) in sequence, an output shaft (43) is formed at the output end of the motor (42), the liquid adding seat (41) has a through hole (411), the output shaft (43) passes through the through hole (411), and is connected to the stirring brush head (45) through a transmission assembly; The stirring seat (44) has at least one stirring groove (441), and each stirring groove (441) can accommodate a stirring brush head (45); It also comprises a liquid storage device (7), wherein the liquid storage device (7) and the metering pump tower (5) are connected via a pipeline, and the liquid in the liquid storage device (7) is injected into the sample adding device (4) by controlling the flow rate via the metering pump tower (5).

2. The spotting machine according to claim 1, characterized in that: Located below the liquid adding seat (41), the transmission assembly comprises a driving gear (47), a first driven gear (48), and a second driven gear (49) fixed above the stirring brush head (45); the driving gear (47) has a driving gear shaft (471), and the first driven gear (48) has a driven gear shaft (481); the driving gear (47) is connected to the output shaft (43) through meshing with the output shaft (43); the first driven gear (48) is connected to the driving gear (47) through meshing with the driving gear shaft (471); the second driven gear (49) is connected to the first driven gear (48) through meshing with the driven gear shaft (481), thereby connecting the output shaft (43) to the stirring brush head (45).

3. The spotting machine according to claim 2, characterized in that: The diameter of the driving gear (47) is smaller than the diameter of the first driven gear (48), and the diameter of the first driven gear (48) is smaller than the diameter of the second driven gear (49).

4. The spotting machine according to claim 1, characterized in that: A motor slot (412) is provided above the liquid adding seat (41), and the motor (42) is located in the motor slot (412) and is sealed by a cover plate (413).

5. The spotting machine according to claim 1, characterized in that: The conveying device (2) has a conveying track (21) for conveying the object to be tested to the sample loading platform. Limiting grooves (22) are also provided on both sides of the conveying device in the direction horizontally and vertically to the conveying track.

6. The spotting machine according to claim 1, characterized in that: The sample loading platform (3) is fixedly provided with a detection device (8), which is electrically connected to the control device (6) and performs real-time detection on the object to be tested transported to the sample loading platform (3) by the conveying device (2).

7. The spotting machine according to claim 6, characterized in that: The detection device (8) is an infrared sensing device. When the conveying device (2) transports the object to be tested to the bottom of the sample loading platform (3), the infrared sensing device detects the arrival of the object to be tested, and the control device (6) then starts the sample loading device (4) to load the sample.

8. The spotting machine according to claim 1, characterized in that: The control device (6) has a display device (9) for displaying and viewing detection information, and the display device has a touch screen (91) for human-computer information interaction.

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