A dual-chamber membrane oxygenator with variable temperature

Abstract

The present invention discloses a dual-chamber membrane oxygenator with variable temperature, comprising an upper cover, a lower cover, an intermediate connecting cover, a core shaft structure, an oxygenation chamber, and a variable temperature chamber; the oxygenation chamber comprises a first oxygenation chamber and a second oxygenation chamber, which are composed of an oxygen pressure membrane and a blocking layer; the core shaft structure comprises an upper core shaft and a lower core shaft, the side wall spaces of the upper core shaft and the lower core shaft are connected through a connecting shaft, and are connected to the oxygen pressure membrane gap; the upper cover, the intermediate connecting cover, and the lower cover are all connected to the gas nozzle; the top and bottom of the first oxygenation chamber are respectively connected to the upper cover and the intermediate connecting cover; the top and bottom of the second oxygenation chamber are respectively connected to the intermediate connecting cover and the lower cover; the variable temperature chamber is composed of a variable temperature membrane and a blocking layer, and is connected to a water nozzle and a blood inlet nozzle, the variable temperature membrane gap is connected to the oxygen pressure membrane gap; the oxygenation chamber is connected to the blood nozzle. The present invention can adjust the blood temperature before the blood undergoes gas exchange, and can also effectively adjust the carbon dioxide and oxygen content in the blood according to demand.

Description

Technical Field

[0001] The invention relates to the field of medical devices, and in particular to a temperature-variable double-chamber membrane oxygenator. Background Art

[0002] The hollow fiber membrane oxygenator (hereinafter referred to as the oxygenator) is the current gold standard for blood oxygenation. During its long-term use, the oxygenator has gradually been applied to more medical fields, such as respiratory support and first aid, from being a device that supports cardiac surgery at the beginning.

[0003] The ability of hemoglobin in the blood to bind oxygen is affected by the partial pressure of carbon dioxide (PCO2). When PCO2 increases, the ability of hemoglobin to bind oxygen decreases. When the oxygenator completes the exchange of blood and gas, the difference in oxygen concentration between the blood side and the gas side directly affects the oxygenation effect of the blood, while the partial pressure of carbon dioxide is mainly related to the flow rate of the gas.

[0004] Currently, all membrane oxygenators on the market are designed with a single gas exchange chamber. This design can only allow one gas or a mixed gas of the same concentration to pass through when in use. Therefore, when the gas flows through the oxygenator, it is necessary to maintain a certain oxygen concentration for adjusting the oxygen content in the blood and to ensure a certain air flow rate to ensure the rapid removal of carbon dioxide. As a result, when in use, the blood oxygen content and carbon dioxide content in the blood cannot be adjusted effectively and quickly, and a large amount of gas is wasted, especially in the respiratory department or when the applicable subjects are the elderly, when better carbon dioxide removal capabilities are required. Summary of the invention

[0005] In view of this, an embodiment of the present invention is intended to provide a dual-chamber membrane oxygenator with variable temperature, which can not only regulate blood temperature but also effectively adjust the carbon dioxide content in the blood and the blood oxygen content in the blood during blood oxygenation. In addition, it can also be used as a separate oxygenator with variable temperature or as a separate carbon dioxide remover with variable temperature.

[0006] To achieve the above object, the technical solution of the present invention is achieved as follows:

[0007] The embodiment of the present invention provides a dual-chamber membrane oxygenator with variable temperature, comprising an upper cover, a lower cover, an intermediate connecting cover, a core shaft structure, an oxygenation chamber, and a variable temperature chamber; the oxygenation chamber comprises a first oxygenation chamber and a second oxygenation chamber, both of which are composed of an oxygen pressure membrane and a blocking layer arranged at the top and bottom of the oxygen pressure membrane; the core shaft structure comprises an upper core shaft and a lower core shaft, the side wall space of the upper core shaft is connected to the lower core shaft through a connecting shaft, and the side wall space of the upper core shaft and the lower core shaft are both connected to the oxygen pressure membrane gap; the upper cover, the intermediate connecting cover, and the lower cover are all connected with a gas nozzle; the top and bottom of the first oxygenation chamber are respectively connected to the upper cover and the intermediate connecting cover; the top and bottom of the second oxygenation chamber are respectively connected to the intermediate connecting cover and the lower cover; the variable temperature chamber is composed of a variable temperature membrane, a blocking layer arranged at the top and bottom of the variable temperature membrane, and is connected with a water nozzle and a blood inlet nozzle, the variable temperature membrane gap is connected with the oxygen pressure membrane gap; the oxygenation chamber is connected with a blood nozzle.

[0008] Furthermore, the variable temperature chamber is connected with a water nozzle and a blood inlet nozzle, including: the variable temperature chamber is connected with a water inlet nozzle, a water outlet nozzle, and a blood inlet nozzle.

[0009] Further, the oxygenation chamber is connected to a bleeding nozzle including:

[0010] The temperature-changing chamber is connected to the second oxygenation chamber, and the first oxygenation chamber is connected to a bleeding nozzle;

[0011] Or the temperature changing chamber is connected to the first oxygenation chamber, and the second oxygenation chamber is connected to a bleeding nozzle.

[0012] Furthermore, the oxygen pressure membrane is composed of a hollow fiber tube, the temperature-variable membrane is composed of a hollow fiber tube, and the blocking layer has a honeycomb structure.

[0013] Furthermore, the blocking layer of the honeycomb structure is aligned and connected with the tube opening of the hollow fiber tube.

[0014] Furthermore, the upper cover is connected to a first air inlet nozzle, the middle connecting cover is connected to a first air exhaust nozzle, and the lower cover is connected to a second air exhaust nozzle.

[0015] Furthermore, a latch switch is provided in the intermediate connection cover for isolating or connecting the gas flow in the first oxygenation chamber and the second oxygenation chamber.

[0016] Furthermore, the mandrel structure also includes: a mandrel connecting block connecting the upper mandrel and the lower mandrel.

[0017] The beneficial effects of the present invention are as follows: 1) The present invention can be used in blood oxygenation to effectively solve the problems of oxygen exchange and carbon dioxide removal, thereby improving oxygenation efficiency; 2) The present invention can also be used as a separate oxygenator with variable temperature; 3) The present invention can also be used as a separate carbon dioxide remover with variable temperature; 4) The present invention can adjust the blood temperature before the blood undergoes gas exchange. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a three-dimensional diagram of a temperature-variable double-chamber membrane oxygenator according to a first embodiment of the present invention;

[0019] Figure 2 This is a cross-sectional structural diagram of a temperature-variable dual-chamber membrane oxygenator according to a first embodiment of the present invention;

[0020] FIG3 (a) is a schematic plan view of the core shaft structure in the temperature-variable dual-chamber membrane oxygenator according to the first embodiment of the present invention;

[0021] FIG3( b ) is a structural diagram of the inner side of the upper core shaft in the temperature-variable dual-chamber membrane oxygenator according to the first embodiment of the present invention;

[0022] Figure 4 It is a schematic diagram of the blood flow from top to bottom and the water flow in the temperature-variable dual-chamber membrane oxygenator according to the first embodiment of the present invention;

[0023] Figure 5 A schematic diagram of a gas flow mode in a temperature-variable double-chamber membrane oxygenator according to a first embodiment of the present invention;

[0024] Figure 6 It is a schematic diagram of the blood flow from bottom to top and the water flow in the temperature-variable dual-chamber membrane oxygenator according to the second embodiment of the present invention;

[0025] Figure 7 A schematic diagram of a gas flow mode in a temperature-variable double-chamber membrane oxygenator according to a second embodiment of the present invention;

[0026] Among them: 1 is the upper cover, 2 is the lower cover, 3 is the middle connecting cover, 4 is the oxygen pressure membrane, 5 is the blocking layer in the oxygenation chamber, 6 is the upper core shaft, 7 is the lower core shaft, 8 is the core shaft connecting block, 9 is the connecting shaft, 10 is the upper core shaft side wall space, 11 is the lower core shaft side wall space, 12 is the first air inlet nozzle, 13 is the first exhaust nozzle, 14 is the second air inlet nozzle, 15 is the second exhaust nozzle, 16 is the variable temperature membrane, 17 is the blocking layer in the variable temperature chamber, 18 is the water inlet nozzle, 19 is the water outlet nozzle, 20 is the blood inlet nozzle, 21 is the variable temperature chamber shell, and 22 is the bleeding nozzle. DETAILED DESCRIPTION

[0027] In order to more thoroughly understand the features and technical contents of the present invention, the implementation of the present invention is described in detail below in conjunction with the accompanying drawings. The attached drawings are only for reference and explanation, and are not used to limit the present invention.

[0028] Figure 1 1 is a perspective view of a first embodiment of the present invention with a variable temperature double-chamber membrane oxygenator, as shown in FIG. Figure 1 As shown, the temperature-variable dual-chamber membrane oxygenator comprises an upper cover 1, a lower cover 2, an intermediate connecting cover 3, a first oxygenation chamber and a temperature-variable chamber between the upper cover 1 and the intermediate connecting cover 3, and a second oxygenation chamber between the intermediate connecting cover 3 and the lower cover 2. The upper cover is connected with a first air inlet nozzle 12 and a water inlet nozzle 18, the intermediate connecting cover is connected with a first air outlet nozzle 13, a water outlet nozzle 19, and a second air inlet nozzle 14, the lower cover is connected with a second air outlet nozzle 15, and the oxygenator is also connected with a blood inlet nozzle 20 and a blood outlet 22.

[0029] Here, the water inlet connected to the upper cover is connected to the variable temperature chamber, and the water outlet connected to the middle connecting cover is also connected to the variable temperature chamber.

[0030] For the specific internal structure, see Figure 2 As shown, Figure 2 The cross-sectional structure diagram of the first embodiment of the present invention with a variable temperature dual-chamber membrane oxygenator includes an upper cover 1, a lower cover 2, an intermediate connecting cover 3, a core shaft structure, an oxygenation chamber, and a variable temperature chamber; the oxygenation chamber includes a first oxygenation chamber and a second oxygenation chamber, both of which are composed of an oxygen pressure membrane 4 and a blocking layer 5 arranged on the top and bottom of the oxygen pressure membrane; the core shaft structure includes an upper core shaft 6 and a lower core shaft 7, the side wall space of the upper core shaft is connected to the side wall space of the lower core shaft through a connecting shaft 9, and the side wall space 10 of the upper core shaft and the side wall space 11 of the lower core shaft are connected to the The gap of the oxygen pressure membrane 4 is connected; the upper cover 1, the middle connecting cover 3, and the lower cover 2 are all connected with an air nozzle; the top and bottom of the first oxygenation chamber are respectively connected to the upper cover 1 and the middle connecting cover 3; the top and bottom of the second oxygenation chamber are respectively connected to the middle connecting cover 3 and the lower cover 2; the variable temperature chamber is composed of a variable temperature membrane 16, and a sealing layer 17 arranged on the top and bottom of the variable temperature membrane, and is connected with a water nozzle and a blood inlet nozzle 20, and the gap of the variable temperature membrane 16 is connected with the gap of the oxygen pressure membrane 4; the oxygenation chamber is connected with a blood nozzle 22.

[0031] Furthermore, the variable temperature chamber is connected with a water nozzle and a blood inlet nozzle, including: the variable temperature chamber is connected with a water inlet nozzle 18, a water outlet nozzle 19, and a blood inlet nozzle 20.

[0032] Here, the water inlet connected to the variable temperature chamber is connected to the upper cover, and the water outlet connected to the variable temperature chamber is connected to the middle connecting cover.

[0033] Further, the oxygenation chamber is connected to a bleeding nozzle including:

[0034] The temperature-changing chamber is connected to the second oxygenation chamber, and the first oxygenation chamber is connected to a bleeding nozzle;

[0035] Or the temperature changing chamber is connected to the first oxygenation chamber, and the second oxygenation chamber is connected to a bleeding nozzle.

[0036] here, Figure 2 The variable temperature chamber is connected to the first oxygenation chamber, so the blood outlet 22 is connected to the second oxygenation chamber.

[0037] Furthermore, the oxygen pressure membrane 4 is composed of a hollow fiber tube, the temperature variable membrane 16 is composed of a hollow fiber tube, and the blocking layer has a honeycomb structure.

[0038] Furthermore, the blocking layer of the honeycomb structure is aligned and connected with the tube opening of the hollow fiber tube.

[0039] Furthermore, the upper cover 1 is connected to a first air inlet nozzle 12 , the middle connecting cover 3 is connected to a first air outlet nozzle 13 and a second air inlet nozzle 14 , and the lower cover 2 is connected to a second air outlet nozzle 15 .

[0040] Here, when blood enters the temperature-changing chamber through the blood inlet 20, the blood fills the temperature-changing membrane 16 composed of a plurality of hollow fiber tubes, that is, the blood spreads over the outer wall of the hollow fiber tube and is separated from the water flow flowing in the hollow fiber tube.

[0041] Accordingly, when blood enters the first oxygenation chamber from the temperature-changing chamber, the blood fills the oxygen pressure membrane 4 composed of a plurality of hollow fiber tubes, that is, the blood spreads over the outer walls of the hollow fiber tubes and is separated from the gas flowing in the hollow fiber tubes.

[0042] Here, the blood enters the first oxygenation chamber from the temperature changing chamber specifically through the holes on the temperature changing chamber shell 21 and enters the first oxygenation chamber.

[0043] Here, the water flow coming in from the water inlet 18 enters into the hollow fiber tube through the honeycomb structure plugging layer, and goes out from the honeycomb structure plugging layer 17 at the bottom of the temperature variable membrane 16 .

[0044] Here, the gas coming in from the first gas inlet nozzle 12 enters the hollow fiber tube through the honeycomb structure blocking layer 5 in the first oxygenation chamber, and goes out from the honeycomb structure blocking layer at the bottom of the oxygen pressure membrane.

[0045] Furthermore, a latch switch is provided in the intermediate connection cover 3 for isolating or connecting the gas flow in the first oxygenation chamber and the second oxygenation chamber.

[0046] Here, an independent two-layer structure is provided in the intermediate connecting cover 3. When the latch switch arranged in the intermediate connecting cover is closed, the first air outlet nozzle 13 and the second air inlet nozzle 14 connected on the intermediate connecting cover are not connected, that is, they work in an independent two-layer structure, and accordingly, the gas flow in the first oxygenation chamber and the second oxygenation chamber is cut off; when the latch switch arranged in the intermediate connecting cover is opened, the first air outlet nozzle 13 and the second air inlet nozzle 14 connected on the intermediate connecting cover 3 are connected, and accordingly, the gas flow in the first oxygenation chamber and the second oxygenation chamber is connected. At this time, the second air inlet nozzle 14 needs to be blocked, that is, the second air inlet nozzle 14 does not pass gas, otherwise the gas passed through the second air inlet nozzle 14 will be directly discharged from the first air outlet nozzle 13.

[0047] Furthermore, the mandrel structure also includes: a mandrel connecting block 8 connecting the upper mandrel 6 and the lower mandrel 7.

[0048] FIG3 (a) is a schematic plan view of the core shaft structure in the temperature-variable dual-chamber membrane oxygenator according to the first embodiment of the present invention. As shown in the figure, the core shaft comprises an upper core shaft 6, a lower core shaft 7, and a core shaft connecting block 8 connecting the upper core shaft and the lower core shaft.

[0049] Here, the core shaft structure is arranged in the middle part of the temperature-variable dual-chamber membrane oxygenator, the center of the core shaft structure is a solid structure, the upper core shaft side wall space 10 and the lower core shaft side wall space 11 are connected to the oxygen pressure membrane gap, and the upper core shaft side wall space 10 and the lower core shaft side wall space 11 are connected through a connecting shaft.

[0050] Here, the upper core shaft side wall space 10 and the lower core shaft side wall space 11 have a gap 101 for blood to pass through on the side in contact with the oxygen pressure membrane gap, so the upper core shaft side wall space and the lower core shaft side wall space are both connected to the oxygen pressure membrane gap.

[0051] FIG3 (b) is a structural diagram of the inner side of the upper core shaft in the first embodiment of the present invention with a variable temperature dual-chamber membrane oxygenator. As shown in the figure, the middle of the upper core shaft 6 is a solid structure, the side wall forms a space 10, and the side in contact with the oxygen pressure membrane gap has a gap 101 for blood to pass through.

[0052] Here, the inner structure of the lower core shaft is the same as the inner structure of the upper core shaft mentioned above, and will not be repeated.

[0053] Figure 4 FIG. 1 is a schematic diagram of the blood flow from top to bottom and the water flow in the variable temperature dual-chamber membrane oxygenator according to the first embodiment of the present invention. Figure 4 As shown, a blood inlet is provided at the bottom of the temperature-changing chamber, and a bleeding outlet is provided at the bottom of the second oxygenation chamber.

[0054] Here, when blood enters the temperature-changing chamber from the blood inlet nozzle, the blood will fill the temperature-changing membrane composed of a plurality of hollow fiber tubes, that is, the blood will cover the outer wall of the hollow fiber tube, and after heat exchange with the water flowing in the hollow fiber tube, the blood will enter the first oxygenation chamber through the holes on the temperature-changing chamber shell. At this time, the blood will also fill the oxygen pressure membrane composed of a plurality of hollow fiber tubes, that is, the blood will cover the outer wall of the hollow fiber tube, and after exchange with the gas molecules flowing in the hollow fiber tube, the blood will flow downward through the side wall space of the upper core shaft connected to the oxygen pressure membrane, and will successively pass through the connecting shaft connecting the lower core shaft and the side wall space of the upper core shaft and the side wall space of the lower core shaft, and then enter the second oxygenation chamber. The blood will also cover the outer wall of the hollow fiber tube, and after exchange with the gas molecules flowing in the hollow fiber tube, the blood will go out from the blood nozzle arranged at the bottom of the second oxygenation chamber.

[0055] Here, the blood undergoes heat exchange in the temperature changing chamber and specifically the temperature of the blood can be controlled by adjusting the temperature of the water flow.

[0056] Here, the gas molecule exchange of the blood in the first oxygenation chamber may specifically be performed by adjusting the flow rate of the gas in the hollow fiber tube to control the carbon dioxide partial pressure in the blood.

[0057] Here, the gas molecule exchange of the blood in the second oxygenation chamber can specifically be achieved by adjusting the oxygen concentration in the gas to control the oxygen partial pressure and blood oxygen saturation in the blood. For example, an air-oxygen mixed gas with an oxygen concentration of 66% is introduced into the second oxygenation chamber to increase the oxygen partial pressure and blood oxygen saturation in the blood to the level required for clinical surgery.

[0058] The above-mentioned method realizes the temperature regulation of blood in the variable temperature double-chamber membrane oxygenator of this embodiment and two complete gas exchange processes. The specific gas flow mode is shown in Figure 5 .

[0059] Figure 5 The present invention is a schematic diagram of a gas flow mode in a dual-chamber membrane oxygenator with variable temperature according to a first embodiment of the present invention. As shown in the figure, the gas enters from a first gas inlet nozzle connected to the upper cover and a second gas inlet nozzle connected to the middle connecting cover, and exits from a first gas outlet nozzle connected to the middle connecting cover and a second gas outlet nozzle connected to the lower cover.

[0060] Here, the intermediate connection cover is provided with an independent two-layer structure.

[0061] Here, the latch switch provided in the intermediate connecting cover is closed, i.e., the gas flow in the first oxygenation chamber and the second oxygenation chamber is cut off, and the independent two-layer structure provided in the intermediate connecting cover works independently, i.e., the gas will not flow from the second air inlet nozzle connected to the intermediate connecting cover to the first air outlet nozzle connected to the intermediate connecting cover.

[0062] Here, the gas enters from the second air inlet nozzle connected to the middle connecting cover, passes through the honeycomb sealing layer into a plurality of hollow fiber tubes connected thereto, and goes out from the honeycomb sealing layer connected to the bottom end of the hollow fiber tubes, and finally goes out through the second air outlet nozzle connected to the lower cover.

[0063] Here, the gas enters from the second air inlet nozzle connected to the middle connecting cover, spreads all around the middle connecting cover having an independent working structure layer, and flows downward through the honeycomb-shaped blocking layer.

[0064] Similarly, the gas enters from the first air inlet nozzle connected to the upper cover, passes through the honeycomb sealing layer into a plurality of hollow fiber tubes connected thereto, and goes out from the honeycomb sealing layer connected to the bottom end of the hollow fiber tube, and finally goes out through the first air outlet nozzle connected to the middle connecting cover.

[0065] Here, the gas entering from the first gas inlet nozzle connected to the intermediate connecting cover can be adjusted in gas flow rate through an additional component, and the carbon dioxide partial pressure in the blood can be controlled by adjusting the speed at which the gas flows in the hollow fiber tube.

[0066] Here, the gas entering from the second gas inlet nozzle connected to the upper cover contains an appropriate amount of oxygen concentration, and the oxygen partial pressure and blood oxygen saturation in the blood are controlled by adjusting the oxygen concentration of the gas flowing in the hollow fiber tube.

[0067] Here, when the temperature-variable double-chamber membrane oxygenator is working, water flows, blood flows, and gas flows simultaneously.

[0068] Figure 6 FIG. 1 is a schematic diagram of the blood flow from bottom to top and the water flow in the double-chamber membrane oxygenator of the second embodiment of the present invention, that is, the variable temperature chamber is arranged in connection with the second oxygenation chamber, such as Figure 6As shown, the bottom of the variable temperature chamber is provided with a blood inlet nozzle, the bottom of the first oxygenation chamber is provided with a bleeding nozzle, and a power pump is provided on the blood inlet nozzle interface connected to the bottom of the variable temperature chamber. Blood enters from the blood inlet nozzle connected to the bottom of the variable temperature chamber and fills the variable temperature membrane composed of a plurality of hollow fiber tubes, that is, the blood is spread on the outer wall of the hollow fiber tube, and after the cold and heat exchange with the water flowing in the hollow fiber tube, it enters the second oxygenation chamber through the hole on the variable temperature shell. At this time, the blood will also fill the oxygen pressure membrane composed of a plurality of hollow fiber tubes, that is, the blood is spread on the outer wall of the hollow fiber tube, and after the exchange with the gas molecules flowing in the hollow fiber tube, it flows upward through the side wall space of the lower core shaft connected to the oxygen pressure membrane, and passes through the connecting shaft connecting the side wall space of the lower core shaft and the side wall space of the upper core shaft in turn, and then enters the first oxygenation chamber, and the blood is also spread on the outer wall of the hollow fiber tube, and after the exchange with the gas molecules flowing in the hollow fiber tube, it goes out from the bleeding nozzle set at the bottom of the first oxygenation chamber.

[0069] It should be noted that in this embodiment, preferably, gas enters the first oxygenation chamber from the first air inlet nozzle connected to the upper cover, and is discharged from the first exhaust nozzle connected to the middle connecting cover and the second exhaust nozzle connected to the bottom of the second oxygenation chamber, that is, the latch switch provided on the middle connecting cover is turned on, connecting the gas flow in the first oxygenation chamber and the second oxygenation chamber. For specific gas flow mode, see Figure 7 .

[0070] Here, the gas flow in the first oxygenation chamber and the second oxygenation chamber is connected, so that the present invention can be used alone as an oxygenator or alone as a carbon dioxide remover.

[0071] The blood undergoes heat exchange in the temperature-changing chamber and the temperature of the blood can be specifically controlled by adjusting the temperature of the water flow.

[0072] The gas molecule exchange of blood in the second oxygenation chamber and the first oxygenation chamber can be specifically carried out by adjusting the oxygen concentration in the gas to control the oxygen partial pressure and blood oxygen saturation in the blood. For example, an air-oxygen mixed gas with an oxygen concentration of 66% flows through the first oxygenation chamber and the second oxygenation chamber to increase the oxygen partial pressure and blood oxygen saturation in the blood to the level required for clinical surgery, that is, the invention is used alone as an oxygenator.

[0073] Alternatively, the gas molecule exchange between the blood in the second oxygenation chamber and the first oxygenation chamber can be specifically carried out by adjusting the flow rate of the gas in the hollow fiber tubes in the first oxygenation chamber and the second oxygenation chamber to control the carbon dioxide partial pressure in the blood, that is, the present invention is used alone as a carbon dioxide remover.

[0074] Here, when the temperature-variable double-chamber membrane oxygenator is working, water flows, blood flows, and gas flows simultaneously.

[0075] Figure 7 FIG. 1 is a schematic diagram of a gas flow mode in a temperature-variable dual-chamber membrane oxygenator according to a second embodiment of the present invention. Figure 7 As shown, Figure 7 The flow mode of the gas in the middle can enable the embodiment of the present invention to be used alone as an oxygenator with variable temperature or alone as a carbon dioxide remover with variable temperature.

[0076] Here, the latch switch provided in the intermediate connecting cover for isolating or connecting the gas flow in the first oxygenation chamber and the second oxygenation chamber is turned on, that is, the gas flow in the first oxygenation chamber and the second oxygenation chamber is connected, that is, the gas enters from the first gas inlet nozzle of the upper cover and goes out from the first gas outlet nozzle connected to the intermediate connecting cover and the second gas outlet nozzle connected to the lower cover respectively.

[0077] Specifically, the gas enters from the first air inlet nozzle connected to the upper cover, covers the entire upper cover, enters the hollow fiber tube from the honeycomb sealing layer in the first oxygenation chamber, flows from the sealing layer at the bottom end of the hollow fiber tube to the middle connecting cover, covers the entire middle connecting cover, a part of the gas goes out from the first air outlet nozzle connected to the middle connecting cover, and the other part of the gas continues to flow into the second oxygenation chamber, that is, enters through the honeycomb sealing layer at the top of the hollow fiber tube in the second oxygenation chamber, comes out from the honeycomb sealing layer at the bottom of the hollow fiber tube, covers the entire lower cover, and goes out from the second air outlet nozzle connected to the lower cover.

[0078] Here, when the gas entering from the first air inlet nozzle connected to the upper cover contains an appropriate amount of oxygen concentration, the embodiment of the present invention can be used alone as an oxygenator with variable temperature; when the gas entering from the first air inlet nozzle connected to the upper cover is adjusted by adjusting the flow rate of the gas in the hollow fiber tube, the embodiment of the present invention can be used alone as a carbon dioxide remover with variable temperature.

[0079] against Figure 4 and Figure 5In the embodiment, the double-chamber membrane oxygenator with variable temperature is used, the water inlet nozzle connected to the upper cover enters water flow at a certain temperature, and enters the hollow fiber tube through the sealing layer of the variable temperature chamber; the first air inlet nozzle connected to the upper cover enters gas with a certain flow rate, and the second air inlet nozzle connected to the middle connecting cover enters gas containing an appropriate amount of oxygen concentration, and enters the hollow fiber tube through the sealing layers of the first oxygenation chamber and the second oxygenation chamber; blood enters the variable temperature membrane composed of a plurality of hollow fiber tubes from the blood inlet nozzle connected to the bottom end of the variable temperature chamber, that is, the blood is spread on the outer wall of the hollow fiber tube, and after heat and cold exchange with the water flow flowing in the hollow fiber tube entering the variable temperature chamber, the blood enters the first oxygenation chamber through the hole on the variable temperature shell, that is, enters the oxygen pressure membrane composed of a plurality of hollow fiber tubes, and the blood The blood is distributed on the outer wall of the hollow fiber tube, and after exchanging with the gas molecules flowing into the hollow fiber tube, it flows downward through the side wall space of the upper core shaft connected to the oxygen pressure membrane, passes through the connecting shaft connecting the upper core shaft and the side wall space of the lower core shaft and the side wall space of the lower core shaft in sequence, and then enters the second oxygenation chamber. The blood is also distributed on the outer wall of the hollow fiber tube, and after exchanging with the gas molecules flowing in the hollow fiber tube, it goes out from the blood nozzle set at the bottom end of the second oxygenation chamber; at the same time, the water flow entering from the water inlet nozzle is discharged from the water outlet nozzle connected to the middle connecting cover; in addition, the gas entering from the first air inlet nozzle connected to the upper cover and the second air inlet nozzle connected to the middle connecting cover respectively goes out from the first air outlet nozzle connected to the middle connecting cover and the second air outlet nozzle connected to the lower cover.

[0080] against Figure 6 and Figure 7In the embodiment, the double-chamber membrane oxygenator with variable temperature is used, the water inlet connected to the middle connecting cover enters water flow at a certain temperature, and enters the hollow fiber tube through the sealing layer of the variable temperature chamber; the first air inlet connected to the upper cover enters gas with a certain flow rate, and enters the hollow fiber tube through the sealing layer of the first oxygenation chamber and the hollow fiber tube in the second oxygenation chamber; blood enters the variable temperature membrane composed of multiple hollow fiber tubes from the blood inlet connected to the bottom end of the variable temperature chamber, that is, blood is spread on the outer wall of the hollow fiber tube, and after heat exchange with the water flow flowing in the hollow fiber tube entering the variable temperature chamber, the blood enters the second oxygenation chamber through the hole on the variable temperature shell, that is, enters the oxygen pressure membrane composed of multiple hollow fiber tubes. Blood is spread all over the outer wall of the hollow fiber tube, and after exchanging with the gas molecules flowing into the hollow fiber tube, it flows upward through the side wall space of the lower core shaft connected to the oxygen pressure membrane, passes through the connecting shaft connecting the lower core shaft and the side wall space of the upper core shaft and the side wall space of the upper core shaft in sequence, and then enters the first oxygenation chamber. The blood is also spread all over the outer wall of the hollow fiber tube, and after exchanging with the gas molecules flowing in the hollow fiber tube, it goes out from the blood nozzle set at the bottom of the first oxygenation chamber; at the same time, the water flow entering from the water inlet nozzle is discharged from the water outlet nozzle connected to the lower cover; in addition, the gas entering from the first air inlet nozzle connected to the upper cover goes out from the first air outlet nozzle connected to the middle connecting cover and the second air outlet nozzle connected to the lower cover respectively.

[0081] The specific models of the above-mentioned devices are not limited or described in detail, and the in-depth connection methods of the above-mentioned devices are not described in detail. As common knowledge, technicians in this field can understand it.

[0082] The embodiments of the present invention are only to introduce the specific implementation methods thereof, and are not intended to limit the protection scope thereof. The technicians in the industry may make some modifications inspired by the embodiments, so any equivalent changes or modifications made according to the scope of the present invention are within the scope of the patent claims of the present invention.

Claims

1. A dual-chamber membrane oxygenator with variable temperature, comprising an upper cover and a lower cover, characterized in that: It also includes an intermediate connecting cover, a core shaft structure, an oxygenation chamber, and a temperature-changing chamber; the oxygenation chamber includes a first oxygenation chamber and a second oxygenation chamber, both of which are composed of an oxygen pressure membrane and a sealing layer arranged on the top and bottom of the oxygen pressure membrane; The core shaft structure comprises an upper core shaft, a lower core shaft, and a core shaft connecting block connecting the upper core shaft and the lower core shaft. The core shaft structure is arranged in the middle of the temperature-variable dual-chamber membrane oxygenator, and the center of the core shaft structure is a solid structure. The side wall space of the upper core shaft and the side wall space of the lower core shaft are connected to the oxygen pressure membrane gap, and the side wall space of the upper core shaft and the side wall space of the lower core shaft are connected through a connecting shaft. There is a gap for blood to pass through on the side where the side wall space of the upper core shaft and the side wall space of the lower core shaft contact the oxygen pressure membrane gap, and the side wall space of the upper core shaft and the side wall space of the lower core shaft are both connected to the oxygen pressure membrane gap. A latch switch is provided in the intermediate connecting cover for isolating or connecting the gas flow in the first oxygenation chamber and the second oxygenation chamber; an independent two-layer structure is provided in the intermediate connecting cover, and when the latch switch provided in the intermediate connecting cover is closed, the first gas outlet nozzle and the second gas inlet nozzle connected on the intermediate connecting cover are not connected, that is, they work in the independent two-layer structure, and accordingly, the gas flow in the first oxygenation chamber and the second oxygenation chamber is isolated; when the latch switch provided in the intermediate connecting cover is opened, the first gas outlet nozzle and the second gas inlet nozzle connected on the intermediate connecting cover are connected, and accordingly, the gas flow in the first oxygenation chamber and the second oxygenation chamber is connected, and at this time, the second gas inlet nozzle is blocked, that is, the second gas inlet nozzle does not pass gas; The upper cover, the middle connecting cover and the lower cover are all connected with a gas nozzle; the top and the bottom of the first oxygenation chamber are respectively connected to the upper cover and the middle connecting cover; the top and the bottom of the second oxygenation chamber are respectively connected to the middle connecting cover and the lower cover; The variable temperature chamber is composed of a variable temperature membrane and a sealing layer arranged on the top and bottom of the variable temperature membrane, and is connected with a water nozzle and a blood inlet nozzle. The variable temperature membrane gap is connected with the oxygen pressure membrane gap; the oxygenation chamber is connected with a blood nozzle.

2. A temperature-variable double-chamber membrane oxygenator according to claim 1, characterized in that: The variable temperature chamber is connected with a water nozzle and a blood inlet nozzle, specifically: the variable temperature chamber is connected with a water inlet nozzle, a water outlet nozzle, and a blood inlet nozzle.

3. The temperature-variable double-chamber membrane oxygenator according to claim 1, characterized in that: The oxygenation chamber is connected with a bleeding nozzle, specifically: the temperature changing chamber is connected with the second oxygenation chamber, and the first oxygenation chamber is connected with a bleeding nozzle; or the temperature changing chamber is connected with the first oxygenation chamber, and the second oxygenation chamber is connected with a bleeding nozzle.

4. The temperature-variable double-chamber membrane oxygenator according to claim 1, characterized in that: The oxygen pressure membrane is composed of a hollow fiber tube, the temperature-variable membrane is composed of a hollow fiber tube, and the blocking layer is in a honeycomb structure.

5. A temperature-variable double-chamber membrane oxygenator according to claim 4, characterized in that: The plugging layer of the honeycomb structure is aligned and connected with the tube opening of the hollow fiber tube.

6. The temperature-variable double-chamber membrane oxygenator according to claim 1, characterized in that: The upper cover is connected with a first air inlet nozzle, the middle connecting cover is connected with a first air outlet nozzle, and the lower cover is connected with a second air outlet nozzle.

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