A kind of plant active ingredient purification method and its application in cosmetics

Abstract

The present invention proposes a method for purifying plant active components, comprising the following steps: S1. Pretreatment: adding NaOH solution to the Okoume tree resin, adjusting the pH value, stirring and mixing, leaving standstill, liquid separation, and washing the organic phase with water , dry; S2. Supercritical fluid extraction, extraction conditions: extraction pressure: 6-12MPa; extraction temperature: 32-40°C; CO 2 Flow rate: 7‑12L / h; extraction time: 1.5‑2.5h; entrainer is 1‑butyl‑3‑methylimidazolium hexafluorophosphate, and the addition amount is 1‑5wt% of the Okoume resin; S3. Purify the extract: add the extract obtained in step S2 to the ionic liquid, and feed CO 2 , to obtain a highly polar ionic liquid, let stand to separate layers, separate liquids, collect an organic layer, wash with water, dry, and filter to obtain the Okoume tree resin extract. The cosmetic of the invention has good anti-aging, anti-oxidation and anti-wrinkle effects.

Description

technical field

[0001] The invention relates to the technical field of cosmetics, in particular to a method for purifying plant active ingredients and its application in cosmetics. Background technique

[0002] Okoume tree, scientific name red walnut, another name: sandalwood, belongs to Burseraceae (Burseraceae), Aucoumea (Aucoumea), mainly distributed in Central Africa, West Africa and Southeast Asian countries, red walnut wooden tube structure is thin and Uniform, smooth wood color, bright color, soft luster, fine tube holes like jade, strong anti-deformation ability, freshly cut red walnut wood surface has a faint woody fragrance, and the wood grain is natural straight grain, flawless, knotless, and scarless Traces, delicate and smooth to the touch. Red walnut wood grows slowly, up to 25-35m, with a diameter of 2-2.5m.

[0003] Okoume tree resin is rich in volatile oil, the main component is carene, accounting for more than 70% of the volatile oil, and the rest are p-c...

Examples

Embodiment 1

[0038] Embodiment 1 A kind of preparation method of Okoume tree resin extract

[0039] Include the following steps:

[0040] S1. Pre-treatment: add 1mol / L NaOH solution to the Okoume resin, adjust the pH value to 8, stir and mix, let stand, separate the liquid, wash the organic phase with water, add a desiccant to dry, and keep it for later use;

[0041] S2. Supercritical fluid extraction: the Okoume tree resin treated in step S1 is extracted by supercritical fluid extraction technology;

[0042] Extraction conditions: extraction pressure: 6MPa; extraction temperature: 32°C; CO 2 Flow rate: 7L / h; extraction time: 1.5h; entrainer: imidazolium-based ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate, the addition amount is 1wt%;

[0043] S3. Purify the extract: Add 10 mL of the extract obtained in step S2 to 50 mL of ionic liquid (the ionic liquid is 1-propyl-3-methylimidazolium tetrafluoroborate), and pass into the ionic liquid with CO 2 To increase the polarity of...

Embodiment 2

[0046] Embodiment 2 A kind of preparation method of Okoume tree resin extract

[0047] Include the following steps:

[0048] S1. Pretreatment: Add 2mol / L NaOH solution to the Okoume resin, adjust the pH value to 10, stir and mix, let it stand, separate the liquid, wash the organic phase with water, add a desiccant to dry, and retain it;

[0049] S2. Supercritical fluid extraction: the Okoume tree resin treated in step S1 is extracted by supercritical fluid extraction technology;

[0050] Extraction conditions: extraction pressure: 12MPa; extraction temperature: 40°C; CO 2 Flow rate: 12L / h; extraction time: 2.5h; entrainer: imidazolium-based ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate, the addition amount is 5wt%;

[0051] S3. Purify the extract: Add 10 mL of the extract obtained in step S2 to 50 mL of ionic liquid (the ionic liquid is 1-propyl-3-methylimidazolium tetrafluoroborate), and pass into the ionic liquid with CO 2 To increase the polarity of ionic ...

Embodiment 3

[0053] Embodiment 3 A kind of preparation method of Okoume tree resin extract

[0054] Include the following steps:

[0055] S1. Pretreatment: add 1.5mol / L NaOH solution to the Okoume resin, adjust the pH value to 9, stir and mix, let it stand, separate the liquid, wash the organic phase with water, add a desiccant to dry, and retain it;

[0056] S2. Supercritical fluid extraction: the Okoume resin treated in step S1 is extracted by supercritical fluid extraction technology to obtain an extract;

[0057] Extraction conditions: extraction pressure: 10MPa; extraction temperature: 36°C; CO 2 Flow rate: 10L / h; extraction time: 2h; entrainer is imidazolium-based ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate, and its addition amount is 3% of the weight of Okoume resin;

[0058] S3. Purify the extract: Add 10 mL of the extract obtained in step S2 to 50 mL of ionic liquid (the ionic liquid is 1-propyl-3-methylimidazolium tetrafluoroborate), and pass into the ionic liq...

technical field

[0001] The invention relates to the technical field of cosmetics, in particular to a method for purifying plant active ingredients and its application in cosmetics. Background technique

[0002] Okoume tree, scientific name red walnut, another name: sandalwood, belongs to Burseraceae (Burseraceae), Aucoumea (Aucoumea), mainly distributed in Central Africa, West Africa and Southeast Asian countries, red walnut wooden tube structure is thin and Uniform, smooth wood color, bright color, soft luster, fine tube holes like jade, strong anti-deformation ability, freshly cut red walnut wood surface has a faint woody fragrance, and the wood grain is natural straight grain, flawless, knotless, and scarless Traces, delicate and smooth to the touch. Red walnut wood grows slowly, up to 25-35m, with a diameter of 2-2.5m.

[0003] Okoume tree resin is rich in volatile oil, the main component is carene, accounting for more than 70% of the volatile oil, and the rest are p-c...

Examples

Embodiment 1

[0038] Embodiment 1 A kind of preparation method of Okoume tree resin extract

[0039] Include the following steps:

[0040] S1. Pre-treatment: add 1mol / L NaOH solution to the Okoume resin, adjust the pH value to 8, stir and mix, let stand, separate the liquid, wash the organic phase with water, add a desiccant to dry, and keep it for later use;

[0041] S2. Supercritical fluid extraction: the Okoume tree resin treated in step S1 is extracted by supercritical fluid extraction technology;

[0042] Extraction conditions: extraction pressure: 6MPa; extraction temperature: 32°C; CO 2 Flow rate: 7L / h; extraction time: 1.5h; entrainer: imidazolium-based ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate, the addition amount is 1wt%;

[0043] S3. Purify the extract: Add 10 mL of the extract obtained in step S2 to 50 mL of ionic liquid (the ionic liquid is 1-propyl-3-methylimidazolium tetrafluoroborate), and pass into the ionic liquid with CO 2 To increase the polarity of...

Embodiment 2

[0046] Embodiment 2 A kind of preparation method of Okoume tree resin extract

[0047] Include the following steps:

[0048] S1. Pretreatment: Add 2mol / L NaOH solution to the Okoume resin, adjust the pH value to 10, stir and mix, let it stand, separate the liquid, wash the organic phase with water, add a desiccant to dry, and retain it;

[0049] S2. Supercritical fluid extraction: the Okoume tree resin treated in step S1 is extracted by supercritical fluid extraction technology;

[0050] Extraction conditions: extraction pressure: 12MPa; extraction temperature: 40°C; CO 2 Flow rate: 12L / h; extraction time: 2.5h; entrainer: imidazolium-based ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate, the addition amount is 5wt%;

[0051] S3. Purify the extract: Add 10 mL of the extract obtained in step S2 to 50 mL of ionic liquid (the ionic liquid is 1-propyl-3-methylimidazolium tetrafluoroborate), and pass into the ionic liquid with CO 2 To increase the polarity of ionic ...

Embodiment 3

[0053] Embodiment 3 A kind of preparation method of Okoume tree resin extract

[0054] Include the following steps:

[0055] S1. Pretreatment: add 1.5mol / L NaOH solution to the Okoume resin, adjust the pH value to 9, stir and mix, let it stand, separate the liquid, wash the organic phase with water, add a desiccant to dry, and retain it;

[0056] S2. Supercritical fluid extraction: the Okoume resin treated in step S1 is extracted by supercritical fluid extraction technology to obtain an extract;

[0057] Extraction conditions: extraction pressure: 10MPa; extraction temperature: 36°C; CO 2 Flow rate: 10L / h; extraction time: 2h; entrainer is imidazolium-based ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate, and its addition amount is 3% of the weight of Okoume resin;

[0058] S3. Purify the extract: Add 10 mL of the extract obtained in step S2 to 50 mL of ionic liquid (the ionic liquid is 1-propyl-3-methylimidazolium tetrafluoroborate), and pass into the ionic liq...

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