A quantitative olfactory detection device

Abstract

The present invention discloses a quantitative olfactory detection device, including a host computer, a control core module and an olfactory diffusion chamber, wherein the host computer is connected to the control core module through a communication port, and the control core module is connected to the olfactory diffusion chamber through an air path; the control core module includes a control unit, a main air pump and an olfactory air pump, the control unit is respectively connected to the main air pump and the olfactory air pump through a speed regulator, the gas outlet of the main air pump is connected to the main air path flow sensor through the main air path, and then connected to the pressure sensor through the mixed air path, the gas outlet of the olfactory air pump is connected to the inlet of the olfactory bottle through the stimulation air path, the outlet of the olfactory bottle is connected to the stimulation air path flow sensor and the concentration sensor in turn through the air path, and then connected to the pressure sensor through the mixed air path, and the mixed gas is delivered to the subject after passing through the pressure sensor. The present invention can accurately feedback the volume concentration of odor molecules, thereby realizing the quantitative olfactory stimulation function.

Description

Technical Field

[0001] The invention relates to a quantitative olfactory detection device and belongs to the field of medical detection. Background Art

[0002] According to surveys, the prevalence of allergic rhinitis in China is about 17.6%, or about 250 million patients. When allergic rhinitis attacks, patients will experience symptoms such as paroxysmal sneezing, watery nasal discharge, nasal congestion and nasal itching, and some patients will also have symptoms of hyposmia. Allergic rhinitis may also cause a variety of diseases including asthma, conjunctivitis, chronic rhinosinusitis, adenoid hypertrophy, and secretory otitis media. Therefore, it is of great social significance to do a good job in the diagnosis of allergic rhinitis.

[0003] At present, the conventional diagnostic methods for allergic rhinitis are clinical observation, skin prick allergy test and serum specific IgE test, which comprehensively judge the allergens of allergic rhinitis. Before and after treatment, the evaluation of treatment effect is often based on the physiological morphology of nasal mucosa and patient self-report, which is difficult to quantitatively analyze. After searching, the currently published patents provide a design scheme for an olfactory test device that uses the presence or absence of different odors to provide an olfactory test, which can qualitatively analyze the degree of olfactory recovery of patients, but cannot achieve quantitative analysis and precise control. Therefore, it is impossible to form an objective tool for evaluating the treatment of allergic rhinitis. For example:

[0004] The olfactory sensitivity detector with application number 2019101403271 proposes a portable solution that uses a worm gear and electric heating to accelerate the escape of gas molecules. The solution has a low degree of automation and does not add a gas concentration sensor to measure the volume concentration of the overflowed odor molecules. Therefore, the odor concentration will be affected by multiple factors such as heating temperature, solution concentration, gas flow rate, etc., making it difficult to achieve quantitative analysis.

[0005] The patented olfactory test device design scheme with application number 2016100440941 is a high-precision olfactory test device. It uses a method of dripping a special solution into a measuring cup and accelerating the escape by stirring. The whole process is in a black box to prevent the color of the colored odor solution from interfering with the olfactory judgment. In this scheme, only the change and control of different odors can be achieved, but due to the lack of quantitative feedback, it is impossible to determine the intensity of the same odor when the patient breathes, so the goal of quantitative analysis cannot be achieved.

[0006] In summary, it is of great significance to realize quantitative testing of olfaction. It can not only more comprehensively reflect the olfactory ability of the subjects, but also quantitative olfactory testing can be applied in many fields such as early diagnosis of Alzheimer's disease, brain science research, psychological research and children's behavior correction. Summary of the invention

[0007] The object of the present invention is to provide a quantitative olfactory detection device, which adopts an adjustable air pump and a flow sensor to accurately control the air path flow, uses an electromagnetic valve and a control unit to select a specific odor and a mixing ratio, and uses a gas concentration sensor to measure the volume concentration of odor molecules, thereby achieving the goal of quantitative testing of olfaction.

[0008] The technical solution adopted by the present invention is: a quantitative olfactory detection device, including a host computer, a control core module and an olfactory diffusion chamber, the host computer is connected to the control core module through a communication port, and the control core module is connected to the olfactory diffusion chamber through an air path; the control core module includes a control unit, a main air pump and an olfactory air pump, the control output end of the control unit is respectively connected to the main air pump and the olfactory air pump through a speed regulator, the gas outlet of the main air pump is connected to the main air path flow sensor through the main air path, and then connected to the pressure sensor through the mixed air path, the gas outlet of the olfactory air pump is connected to the inlet of the olfactory bottle through the stimulation air path, the outlet of the olfactory bottle is connected to the stimulation air path flow sensor and the concentration sensor in sequence through the air path, and then connected to the pressure sensor through the mixed air path, the mixed gas is delivered to the subject after passing through the pressure sensor, the main air path flow sensor, the stimulation air path flow sensor, the concentration sensor and the pressure sensor are all connected to the control unit through a signal line, and the detected signals are sent to the control unit.

[0009] Furthermore, a main gas circuit electromagnetic main valve is provided at the front end of the main gas circuit and close to the outlet of the main air pump.

[0010] Furthermore, a stimulation gas circuit electromagnetic main valve is provided at the front end of the stimulation gas circuit and close to the outlet of the olfactory hormone air pump.

[0011] Furthermore, the tail end of the stimulation gas circuit is divided into a plurality of branches connected in parallel, and each branch is serially connected with a branch solenoid valve and an olfactory substance bottle in sequence, and the outlets of the olfactory substance bottles on each branch are connected to the stimulation gas circuit flow sensor after converging.

[0012] Furthermore, the control unit adopts an embedded control processor.

[0013] Furthermore, the control core module also includes a display screen and buttons, and the control unit can be set through the display screen and buttons.

[0014] Furthermore, the host computer is connected to the control core module via a network port or a USB port, the control instruction information between the host computer and the control core module is bidirectionally transmitted, and the status information is unidirectionally fed back to the host computer by the control core module.

[0015] The beneficial effects of the present invention are as follows: compared with the current existing technology, the present invention adds a gas concentration sensor in the olfactory diffusion gas path to form a feedback loop, which can accurately feedback the volume concentration of odor molecules, thereby realizing the quantitative olfactory stimulation function; at the same time, a pressure sensor is added to the mixed gas path output to collect air flow pressure fluctuation information, which can realize the calculation of the volume and flow rate of the inhaled gas of the subject. The other existing solutions are currently open-loop control, which cannot achieve stable and controllable odor molecules and cannot achieve quantitative testing of air energy.

[0016] This solution uses all electrified components and modular design, which can quickly achieve functional expansion and upgrading at a low cost.

[0017] This scheme can realize quantitative mixed testing of multiple different odor molecules. Compared with the single odor test of other testing schemes, it can more comprehensively reflect the olfactory ability of the subjects and improve the test dimension. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is the overall structure diagram of the quantitative olfactory detection device.

[0019] Figure 2 It is a structural diagram of the control core module.

[0020] Figure 3 It is a schematic diagram of the structure of the olfactory hormone diffusion chamber. DETAILED DESCRIPTION

[0021] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments.

[0022] like Figures 1 to 3 As shown, a quantitative olfactory detection device includes a host computer, a control core module and an olfactory diffusion chamber. The host computer is connected to the control core module through a network port, a USB port or other communication ports. The control instruction information between the host computer and the control core is bidirectionally transmitted, and the status information is fed back to the host computer unidirectionally by the control core module. The control core module is connected to the olfactory diffusion chamber through two air paths. The olfactory diffusion chamber mainly switches the air path and mixes the odor according to the control instruction of the control core, and feeds back the concentration and pressure of the odor molecules to the control core module.

[0023] In this embodiment, the control core module includes a control unit, a main air pump and an olfactory pump, wherein the control output end of the control unit is connected to the main air pump and the olfactory pump respectively through a speed regulator, the gas outlet of the main air pump is connected to the main air flow sensor through the main air path, and then connected to the pressure sensor through the mixed air path, and a main air path electromagnetic main valve is provided at the front end of the main air path and near the outlet of the main air pump. The gas outlet of the olfactory pump is connected to the inlet of the olfactory bottle through the stimulation air path, and the outlet of the olfactory bottle is connected to the stimulation air path flow sensor and the concentration sensor in sequence through the air path and then connected to the pressure sensor through the mixed air path, and the mixed gas is delivered to the subject after passing through the pressure sensor, wherein a stimulation air path electromagnetic main valve is provided at the front end of the stimulation air path and near the outlet of the olfactory pump, and the tail end of the stimulation air path is divided into multiple branches connected in parallel, and each branch is sequentially connected with a branch electromagnetic valve and an olfactory bottle in series, and the outlets of the olfactory bottles on each branch are connected to the stimulation air path flow sensor after converging. The main gas path flow sensor, stimulation gas path flow sensor, concentration sensor and pressure sensor are all connected to the control unit via signal lines, and the detected signals are sent to the control unit.

[0024] The working principle of this device is as follows: the control core provides the main airway airflow and the stimulation airway airflow to the olfactory diffusion chamber through an air pump. The olfactory diffusion chamber opens the designated olfactory bottle airway according to the solenoid valve control instruction, allowing the airflow in the stimulation airway to bring out the olfactory molecules and produce a stimulating odor. The gas in the stimulation airway passes through the concentration sensor and is mixed with the colorless and odorless air in the main airway. After dilution, a mixed airflow with a fixed total gas flow rate and a fixed odor molecule concentration for the experiment is formed, which is delivered to the subject through the mixed airway to carry out the test of the subject. In the olfactory diffusion chamber, pressure sensors, concentration sensors, flow sensors and other sensors provide real-time feedback of various airflow information to the control core module.

[0025] Control core module: The control core mainly includes an embedded system control unit, which is responsible for receiving feedback signals from various sensors, interacting with the host computer, displaying real-time system information on a simple display screen and receiving key commands, controlling the working status and output flow of the air pump, and controlling the opening and closing of the solenoid valve. The voltage regulator receives the control core command and adjusts the output voltage to adjust the output flow of the main air pump. The main air pump outputs colorless and odorless air, and the main air circuit solenoid valve controls whether the main air circuit outputs; similarly, the olfactory pump is controlled by the voltage regulator to output flow, and the stimulated air circuit solenoid valve controls whether it outputs.

[0026] Under normal working conditions, the embedded system control unit calculates the output flow of the main gas pump and the olfactory pump according to the concentration flow information set by the host computer, and then infers the control voltage value according to the voltage flow curve, and gives the speed regulators of the two gas paths through control commands, and opens the solenoid valve. At the same time, the embedded system also receives real-time feedback from signals such as pressure, flow and concentration in the olfactory diffusion chamber, and continuously calculates and optimizes the control voltage value to ensure the stability of the concentration and flow of the mixed airflow smelled by the subjects.

[0027] Olfactory diffusion chamber: flow sensor, pressure sensor and concentration sensor feed back various data to the control core to optimize the control parameters in real time. The solenoid valve determines which branch or branches the airflow generated by the olfactory pump passes through to mix with the air temperature molecules. After the mixed gas passes through the flow sensor and concentration sensor, it is fed back to the control core flow and concentration parameters. It is then mixed with the colorless and odorless air in the main air path to form the final olfactory test gas, which is supplied to the subject. Through the pressure sensor, the volume and flow rate of the subject's breathing gas can be effectively calculated.

[0028] Under normal working conditions, in the olfactory control room, according to the instructions of the control core, the solenoid valves of the designated olfactory bottle branches are opened and closed in the required order and time, thereby realizing a system to switch between different olfactory stimulation odor tests. After the information of the two flow sensors and the concentration sensor is fed back to the control core, the control core calculates and outputs the real-time output of the mixed air flow flow and concentration information. Combined with the fluctuation information of the pressure sensor and the geometric structure information of the system, the mixed gas flow inhaled by the subject can be calculated, thereby realizing the quantitative test of the sense of smell.

[0029] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the above embodiments do not limit the protection scope of the present invention in any form, and all technical solutions obtained by equivalent replacement and the like fall within the protection scope of the present invention.

[0030] The parts not involved in the present invention are the same as the prior art or can be implemented by using the prior art.

Claims

1. A quantitative olfactory detection device, comprising a host computer, a control core module and an olfactory diffusion chamber, wherein the host computer is connected to the control core module via a communication port, and the control core module is connected to the olfactory diffusion chamber via an air path; characterized in that: The control core module includes a control unit, a main air pump and an olfactory element air pump. The control output end of the control unit is respectively connected to the main air pump and the olfactory element air pump through a speed regulator. The gas outlet of the main air pump is connected to the main air path flow sensor through the main air path, and then connected to the pressure sensor through the mixed air path. The gas outlet of the olfactory element air pump is connected to the inlet of the olfactory element bottle through the stimulation air path. The outlet of the olfactory element bottle is connected to the stimulation air path flow sensor and the concentration sensor in sequence through the air path, and then connected to the pressure sensor through the mixed air path. The mixed gas is delivered to the subject after passing through the pressure sensor. The main air path flow sensor, the stimulation air path flow sensor, the concentration sensor and the pressure sensor are all connected to the control unit through a signal line, and the detected signals are sent to the control unit.

2. A quantitative olfactory detection device according to claim 1, characterized in that: A main gas circuit electromagnetic main valve is provided at the front end of the main gas circuit and close to the outlet of the main gas pump.

3. A quantitative olfactory detection device according to claim 1, characterized in that: A stimulation gas circuit electromagnetic main valve is arranged at the front end of the stimulation gas circuit and close to the outlet of the olfactory element gas pump.

4. A quantitative olfactory detection device according to claim 3, characterized in that: The tail end of the stimulation gas circuit is divided into a plurality of branches connected in parallel, and each branch is serially connected with a branch electromagnetic valve and an olfactory substance bottle in sequence, and the outlets of the olfactory substance bottles on each branch are connected to the stimulation gas circuit flow sensor after converging.

5. A quantitative olfactory detection device according to claim 1, characterized in that: The control unit adopts an embedded control processor.

6. A quantitative olfactory detection device according to claim 1 or 5, characterized in that: The control core module also includes a display screen and buttons, and the control unit can be set through the display screen and buttons.

7. A quantitative olfactory detection device according to claim 1, characterized in that: The host computer is connected to the control core module via a network port or a USB port. The control instruction information between the host computer and the control core module is bidirectionally transmitted, and the status information is unidirectionally fed back to the host computer by the control core module.

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