A pulmonary artery thrombosis treatment platform

Abstract

The present invention relates to a pulmonary artery thrombus treatment platform, comprising a suction catheter, a thrombus breaking device, and a suction pump; the thrombus breaking device comprises one or more of a first thrombus breaking component, a second thrombus breaking component, and a third thrombus breaking component; the first thrombus breaking component comprises a first-first catheter, a first-second catheter, and a first agitator; the first agitator comprises a plurality of baskets sequentially arranged along the axis of the first-first catheter, and the maximum diameters of the plurality of baskets in an open state decrease sequentially from the distal end to the proximal end; the second thrombus breaking component comprises a second-first catheter, a second-second catheter, and a second agitator; the second agitator is linear and curved in an open state; the third thrombus breaking component comprises a third-first catheter, a third-second catheter, and a third agitator; the third agitator is sheet-shaped and curved in an open state. The present invention can remove pulmonary artery thrombi while ensuring relative safety, and is particularly suitable for removing thrombi at the bifurcation of the pulmonary artery and capillaries.

Description

Technical Field

[0001] The present invention belongs to the field of medical devices, and in particular relates to a pulmonary artery thrombosis treatment platform. Background Art

[0002] Pulmonary embolism (PE) is a potentially life-threatening disease and one of the leading causes of death in hospitalized patients. In the United States, nearly 600,000 patients experience symptomatic PE each year, of which 200,000 are fatal. The mortality rate of patients diagnosed with PE is 15% to 22%. PE is mainly caused by the detachment of venous thrombosis in the lower extremities. PE and deep vein thrombosis (DVT) are considered to be manifestations of the same disease in different parts, collectively referred to as venous thromboembolism (VTE). A study by the Vascular Surgery Center of Beijing Century Memorial Hospital showed that 45% of patients with DVT developed PE and 4% were fatal PE. Anticoagulation is the main method for treating VTE. When anticoagulation is contraindicated or bleeding complications occur, anticoagulation must be terminated. Traditional surgical methods for treating pulmonary embolism are mainly open thrombectomy and pulmonary endarterectomy, which are traumatic. At present, endovascular treatment has become an effective and important treatment for acute pulmonary embolism. Common treatment methods now include guidewire catheter thrombus fragmentation, thrombus aspiration, catheter thrombolysis and other treatment surgical methods. When existing instruments are used alone to remove thrombi, the effect of removing large pulmonary artery thrombi is not ideal. Summary of the invention

[0003] The technical problem to be solved by the present invention is to provide a pulmonary artery thrombus treatment platform that is suitable for the pulmonary artery and has a good thrombus removal effect.

[0004] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0005] From the product structure point of view, the pulmonary artery thrombus treatment platform of the present invention includes a suction catheter with a suction channel. The thrombus treatment platform also includes a thrombus crushing device and a suction pump connected to the proximal end of the suction catheter;

[0006] The bolt-breaking device includes one or more of a first bolt-breaking assembly, a second bolt-breaking assembly, and a third bolt-breaking assembly;

[0007] The first plug-breaking assembly comprises a first first conduit, a first second conduit slidably sleeved outside the first first conduit, and a first agitator disposed at the distal end of the first first conduit and having an open state and a closed state; the first agitator comprises a plurality of mesh baskets sequentially disposed along the axis of the first first conduit, wherein the maximum diameters of the plurality of mesh baskets in the open state decrease sequentially from the distal end to the proximal end;

[0008] The second plug-breaking assembly comprises a second first conduit, a second second conduit slidably sleeved outside the second first conduit, and a second agitator disposed at the distal end of the second first conduit and having an open state and a retracted state; the second agitator is linear and curved in the open state;

[0009] The third plug-breaking assembly includes a third-first catheter, a third-second catheter slidably mounted outside the third-first catheter, and a third agitator arranged at the distal end of the third-first catheter and having an open state and a retracted state; the third agitator is sheet-shaped and is curved when in the open state.

[0010] From the perspective of product usage, the pulmonary artery thrombus treatment platform includes a suction catheter with a suction channel, and the thrombus treatment platform also includes a thrombus crushing device and a suction pump connected to the proximal end of the suction catheter;

[0011] The bolt-breaking device includes one or more of a first bolt-breaking assembly, a second bolt-breaking assembly, and a third bolt-breaking assembly;

[0012] The first plug-breaking assembly comprises a first conduit passing through the suction channel, a first second conduit passing through the suction channel and slidably sleeved outside the first conduit, and a first agitator arranged at the distal end of the first conduit and having an open state and a retracted state; the first agitator comprises a plurality of mesh baskets arranged in sequence along the axis of the first conduit, wherein the maximum diameters of the plurality of mesh baskets in the open state decrease in sequence from the distal end to the proximal end; when the first agitator is in the open state, the first agitator extends out of the distal end of the suction conduit;

[0013] The second plug-breaking assembly includes a second first conduit passing through the suction channel, a second second conduit passing through the suction channel and slidably sleeved outside the second first conduit, and a second agitator disposed at the distal end of the second first conduit and having an open state and a retracted state; the second agitator is linear and curved in the open state; when the second agitator is in the open state, the second agitator extends out of the distal end of the suction conduit;

[0014] The third plug-breaking assembly includes a third-first catheter passing through the suction channel, a third-second catheter passing through the suction channel and slidably mounted outside the third-first catheter, and a third agitator arranged at the distal end of the third-first catheter and having an open state and a retracted state; the third agitator is sheet-shaped and is curved in the open state; when the third agitator is in the open state, the third agitator extends out of the distal end of the suction catheter.

[0015] Preferably, the plurality of baskets are flat in an open state, and the inner diameter of each basket along the radial direction of the first conduit is larger than the inner diameter along the axial direction of the first conduit.

[0016] Preferably, a connecting component is provided between two adjacent baskets.

[0017] Preferably, the first agitator is braided.

[0018] Preferably, the second plug-breaking assembly and / or the third plug-breaking assembly further comprises a motor connected to the proximal end of the second first catheter or the proximal end of the third first catheter and capable of driving the second agitator or the third agitator to rotate around its own axis.

[0019] Preferably, the suction pump includes a shell having an internal cavity, a first opening arranged on the shell and capable of communicating with the suction catheter, a first one-way valve arranged at the first opening and capable of closing the first opening, a second opening arranged on the shell and capable of communicating with the outside, a second one-way valve arranged at the second opening and capable of closing the second opening, a piston slidably arranged in the shell and having an internal channel, a sealing sheet fixedly arranged on the piston and having a third opening communicating with the internal channel, a third one-way valve arranged at the third opening and capable of closing the third opening, a first handle rotatably connected to the shell, and a second handle rotatably connected to the piston and capable of driving the piston to slide; the first handle is rotatably connected to the second handle, and the sealing sheet is located between the first opening and the second opening; when the first handle and the second handle are operated to move the sealing sheet toward the direction of the second opening, the first opening is opened and the second opening is closed; when the sealing sheet moves toward the direction of the first opening, the first opening is closed; when the thrombus pressure in the internal cavity is greater than the air pressure, the third opening is opened.

[0020] Further preferably, a partition plate is fixedly disposed in the shell to divide the cavity into two parts, a fourth opening communicating with the third opening is formed on the partition plate, and the sealing sheet is located between the partition plate and the second opening.

[0021] Further preferably, the first handle is formed with a bending portion bent toward the second handle.

[0022] Preferably, the outer diameter of the suction catheter is 6F to 14F.

[0023] Preferably, the suction catheter includes a catheter portion having the suction channel, an operating portion movably connected to the proximal end of the catheter portion, a fixing member fixedly arranged on the catheter portion, a connecting member respectively connected to the operating portion and the fixing member and capable of bending the distal end of the catheter portion by operating the operating portion, and a developing ring fixedly arranged at the distal end of the catheter portion.

[0024] Further preferably, the operating part includes a first operating part movably connected to the proximal end of the catheter part, and a second operating part movably connected to the proximal end of the catheter part, and the connecting member includes a first connecting member and a second connecting member; the first connecting member and the second connecting member respectively have two distal end portions located at the distal end and a portion located at the proximal end, the two distal end portions of the first connecting member are respectively arranged on opposite sides of the catheter part, and the proximal end of the first connecting member is wrapped around the first operating part; the two distal end portions of the second connecting member are respectively arranged on opposite sides of the catheter part, and the proximal end of the second connecting member is wrapped around the second operating part; and the two distal ends of the first connecting member and the two distal ends of the second connecting member are evenly distributed along the circumference of the catheter part; when the first operating member and the second operating member are operated, the front end of the catheter part can be directionally rotated in three-dimensional space.

[0025] In the present invention, the axis center line of the connecting member is parallel to the axis center line of the conduit portion and does not overlap.

[0026] The present invention enables medical personnel to operate the operating part so that the movement of the operating part drives the movement of the connecting part, and the connecting part further pulls the fixing part to bend the catheter part, thereby causing an angular offset between the distal end of the catheter part and the proximal end of the catheter part, thereby facilitating the adjustment of the angle of the suction catheter head according to clinical needs, for example, facilitating insertion into a bifurcated blood vessel, etc.

[0027] Preferably, the bolt-breaking device further comprises a fourth bolt-breaking assembly, the fourth bolt-breaking assembly comprising a fourth first catheter, a fourth second catheter slidably sleeved outside the fourth first catheter, and a fourth agitator arranged at the distal end of the fourth first catheter and having an open state and a retracted state; the distal end of the fourth first catheter extends out of the fourth second catheter; the fourth agitator comprises a plurality of wires; the distal end of each of the wires is fixedly connected to the fourth first catheter, and the proximal end is fixedly connected to the fourth second catheter; and at least some of the wires intersect; at least some of the wires rotate around the fourth first catheter at a certain angle; the material of the wires is one or more of nickel-titanium alloy, stainless steel wire, and high molecular polymer. When the fourth first catheter moves toward the proximal end relative to the fourth second catheter, the fourth agitator is opened, and as the moving distance of the fourth first catheter increases, the degree of expansion of the fourth agitator increases, and the outer diameter of the fourth agitator increases; when the fourth first catheter moves toward the distal end relative to the fourth second catheter until the wires are straightened, the fourth agitator is in a retracted state, at which time the outer diameter of the fourth agitator is the smallest and basically fits on the fourth first catheter.

[0028] The angle at which the thread rotates around the fourth conduit can be determined according to the length of the thread and the maximum outer diameter required when the agitator is in the open state.

[0029] Further preferably, the proximal end of the fourth-first catheter is provided with an injection hole for injecting thrombolytic drugs, and the distal end of the fourth-first catheter and / or the silk thread are formed with a plurality of thrombolytic holes for the thrombolytic drugs to enter the blood vessels.

[0030] The proximal end in this article is defined as the side close to the medical staff when the thrombus management platform is in use; the distal end is defined as the side away from the medical staff when the thrombus management platform is in use.

[0031] The aspiration catheter of the present invention can not only have the thrombus removal function itself, but also provide a passage for other thrombus removal devices, thereby facilitating doctors to select surgical plans for different thrombi, thereby making the thrombus treatment platform of the present invention have a wide range of indications.

[0032] Of course, for some thrombotic diseases that can be treated only by suction through a suction catheter, medical personnel may only use the suction catheter of the present invention without using a thrombus-breaking device or the like.

[0033] In the present invention, the suction catheter, the embolus breaking device, and the suction pump are separately packaged, and the components in each separate package can be sold as a whole or individually, so as to facilitate selective use by medical staff. Of course, the suction catheter, the embolus breaking device, and the suction pump can also be put in one package and sold as a whole.

[0034] According to one embodiment, the thrombus treatment platform further includes a guide wire. This product can be sold together with a guide wire, or a guide wire from another manufacturer can be used.

[0035] Due to the implementation of the above technical solution, the present invention has the following advantages compared with the prior art:

[0036] The present invention can remove pulmonary artery thrombus while ensuring relative safety, and is particularly suitable for removing thrombus at the bifurcation of the pulmonary artery and capillaries. The amount of blood loss is controllable, the operation steps are simple, the operation time is shortened, and the patient's hospitalization expenses are reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Attached Figure 1 is a schematic structural diagram of a suction catheter according to a specific embodiment;

[0038] Attached Figure 2 is a partial cross-sectional schematic diagram of a suction catheter according to a specific embodiment;

[0039] Attached Figure 3 is a schematic cross-sectional view of a suction catheter according to a specific embodiment;

[0040] Attached Figure 4 It is a schematic diagram of the suction catheter of a specific embodiment at 0° and ±30° bends;

[0041] Attached Figure 5 It is a structural schematic diagram of a first breaking bolt assembly according to a specific implementation method;

[0042] Attached Figure 6 It is a structural schematic diagram of a second plug-breaking assembly according to a specific implementation method;

[0043] Attached Figure 7 It is a structural schematic diagram of a third bolt-breaking assembly according to a specific implementation method;

[0044] Attached Figure 8 It is a structural schematic diagram of a fourth plug-breaking assembly according to a specific implementation method;

[0045] Attached Fig. 9 This is a state diagram of the suction catheter and the first plug-breaking assembly being matched;

[0046] Attached Fig.10 is a cross-sectional view of a suction pump according to a specific embodiment when pumping negative pressure;

[0047] Attached Fig.11 It is a cross-sectional view of a specific embodiment of the suction pump after release. DETAILED DESCRIPTION

[0048] In the following, only some exemplary embodiments are briefly described. As those skilled in the art will appreciate, the described embodiments may be modified in various ways without departing from the spirit or scope of the embodiments of the present invention. Therefore, the drawings and descriptions are considered to be exemplary and non-restrictive in nature.

[0049] In the description of the embodiments of the present invention, it should be understood that the terms "length", "inside", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the embodiments of the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the embodiments of the present invention.

[0050] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of the embodiments of the present invention, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0051] In the embodiments of the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or a communication; it can be a direct connection, or an indirect connection through an intermediate medium, and it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific circumstances.

[0052] In the embodiments of the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0053] The disclosure below provides many different embodiments or examples to implement different structures of the embodiments of the present invention. In order to simplify the disclosure of the embodiments of the present invention, the parts and settings of specific examples are described below. Of course, they are only examples, and the purpose is not to limit the embodiments of the present invention. In addition, the embodiments of the present invention can repeat reference numbers and / or reference letters in different examples, and this repetition is for the purpose of simplification and clarity, which itself does not indicate the relationship between the various embodiments and / or settings discussed.

[0054] The orientation of this embodiment is defined by the orientation of the thrombus filtering device when in use, wherein the side close to the operator is the proximal end, and the side away from the operator is the distal end.

[0055] The embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0056] The pulmonary artery thrombus treatment platform of the present invention comprises a suction catheter 10 having a suction channel, a suction pump 50, a thrombus breaking device, and the like.

[0057] Attached Figures 1 to 4 1 is a schematic diagram of the structure of the suction catheter 10. The suction catheter 10 comprises a catheter portion having a suction channel, the suction channel extending along the axial direction of the catheter portion and penetrating the catheter portion, and the outer diameter of the catheter portion is 6F to 14F.

[0058] The catheter portion includes a first wall layer 11 located on the inner side, a second wall layer 12 located on the outer side, and a support member 13 arranged between the first wall layer 11 and the second wall layer 12. The support member 13 includes a plurality of repeating bodies continuously arranged along the axial direction of the catheter portion, wherein the spacing between the repeating bodies of the support member 13 changes from the proximal end to the distal end, so that the catheter portion is composed of a first tube portion 1 located at the proximal end, a second tube portion 2 located at the distal end, and a third tube portion 3 located between the first tube portion 1 and the second tube portion 2, and the spacing between two adjacent repeating bodies at the position of the first tube portion 1 and the spacing between two adjacent repeating bodies at the position of the second tube portion 2 is smaller than the spacing between two adjacent repeating bodies at the position of the third tube portion 3, so that the hardness of the third tube portion 3 is smaller than the hardness of the first tube portion 1 and the second tube portion 2, thereby better realizing the bending of the second tube portion 2 relative to the first tube portion 1.

[0059] The support member 13 composed of multiple repeating bodies can be a spiral shape similar to a spring, or can be a structure similar to an accordion. When the support member 13 is a spiral shape, the spacing between the repeating bodies is the pitch. When the support member 13 is an accordion structure, the spacing between the repeating bodies is the distance between two adjacent wave peaks. In this embodiment, the support member 13 is preferably a spiral shape.

[0060] As for the bending angle of the second tube portion 2 relative to the first tube portion 1, it can be achieved by adjusting the spacing between the repeating bodies and the material of the conduit portion. In this embodiment, the material of the support member 13 is metal, such as 304 stainless steel, nickel-titanium alloy wire, etc.; the material of the first wall layer 11 and the second wall layer 12 is polytetrafluoroethylene (PTFE), segmented polyetheramide (Pcbax), polyimide (PI), polyamide (PA), polyethylene (PE), metal film, etc. Preferably, the first wall layer 11 adopts polytetrafluoroethylene (PTFE) with better lubricity, and the second wall layer 12 adopts segmented polyetheramide (Pcbax) metal film, etc., and the second wall layer 12 of the first tube portion 1, the second tube portion 2, and the third tube portion 3 can be spliced ​​with different materials.

[0061] The suction catheter 10 further comprises a fixing member 15 fixedly arranged at the far end of the third tube portion 3 of the catheter portion, and the fixing member 15 of this embodiment is a developing ring, which is fixed between the first wall layer 11 and the second wall layer 12 by heat melting or welding.

[0062] The suction catheter 10 also includes a connector fixedly connected to the fixing member 15 at the distal end and an operating portion rotatably connected to the proximal end of the catheter portion. The connector is located between the first wall layer 11 and the second wall layer 12 and extends along the axial direction of the catheter portion, so that the axis of the connector is parallel to the axis of the catheter portion and does not overlap, and the connector can drive the second tube portion 2 to bend, so that the suction catheter 10 can be bent in a unidirectional range of 120°.

[0063] The suction catheter 10 further includes a developing ring 5 disposed at the distal end of the catheter portion (ie, the distal end position of the second tube portion 2 ).

[0064] The operating part includes a first operating part 41 movably connected to the proximal end of the catheter part, and a second operating part 42 movably connected to the proximal end of the catheter part. The connecting member includes a first connecting member 21 wound around the first operating part 41, and a second connecting member 22 wound around the second operating part 42. The two distal ends of the first connecting member 21 are respectively arranged on opposite sides of the fixing member 15, and the two distal ends of the second connecting member 22 are respectively arranged on opposite sides of the fixing member 15, and the two distal ends of the first connecting member 21 and the two distal ends of the second connecting member 22 are evenly distributed along the circumference of the fixing member 15, so that the head end of the catheter part can be rotated 360° by simultaneously operating the first operating part 41 and the second operating part 42.

[0065] The first operating portion 41 and the second operating portion 42 are located at both sides of the catheter portion, so that the hemostatic valve 7 can be easily disposed at the proximal end of the catheter portion.

[0066] The present invention can accurately control the bending direction and bending angle of the front end of the catheter portion by rotating the operating portion. For example, the diameter of the operating portion can be adjusted by calculation, so that the front end of the catheter portion can be bent at a certain angle, such as 1°, 2°, 3°, etc., every time the operating portion is rotated one circle. Of course, in order to avoid excessive workload for medical staff, the bending angle of the catheter portion caused by each rotation of the operating portion can be set to 5°, etc.

[0067] The suction catheter 10 of the present invention also includes a three-way valve 8 connected to the proximal end of the catheter part. Medical staff can introduce physiological saline, thrombolytic agents, etc. into the catheter part through the three-way valve 8, and can also connect the suction pump 50 through the three-way valve 8 to suction thrombus.

[0068] The present invention operates the operating part through the operator so that the movement of the operating part drives the movement of the connecting part, and the connecting part further pulls the catheter wall to bend the catheter part, thereby causing an angular offset between the distal end of the catheter part and the proximal end of the catheter part, thereby facilitating the adjustment of the angle of the head of the suction catheter 10 according to clinical needs. For example, the suction catheter 10 can be used to enter a blood vessel. By adjusting the angle of the head end, it can be more convenient to insert into a bifurcated blood vessel, or the angle can be adjusted to aspirate a thrombus at a specific position, etc.

[0069] like Fig.10 and 11 The specific structure of the suction pump 50 includes a housing 51 having an internal cavity, a first opening 52 disposed on the housing 51 and capable of communicating with the suction conduit 10, a first one-way valve 53 disposed at the first opening 52 and capable of closing the first opening 52, a second opening 54 disposed on the housing 51 and capable of communicating with the outside, a second one-way valve 55 disposed at the second opening 54 and capable of closing the second opening 54, a piston 56 slidably disposed in the housing 51 and having an internal passage, a sealing sheet 58 fixedly disposed on the piston 56 and having a third opening 57 communicating with the internal passage, a third one-way valve 59 disposed at the third opening 57 and capable of closing the third opening 57, a first handle 60 rotatably connected to the housing 51, and a second handle 61 rotatably connected to the piston 56 and capable of driving the piston 56 to slide. The first handle 60 is rotatably connected to the second handle 61.

[0070] The sealing sheet 58 is located between the first opening 52 and the second opening 54, thereby dividing the internal volume into two parts. When the first handle 60 and the second handle 61 are operated to move the sealing sheet 58 toward the second opening 54, the blood clot pushes the first check valve 53 to open the first opening 52 under the state of negative pressure pumped by the sealing sheet 58, and the second check valve 55 closes the second opening 54 under the push of the internal air pressure, and the third check valve 59 closes the third opening 57 because the pressures on both sides are equal. When the first handle 60 and the second handle 61 are released, the external air pressure opens the second check valve 55 to allow air to enter, and the sealing sheet 58 squeezes the blood clot pumped into the internal volume, and the first check valve 53 is closed under the action of the blood clot pressure. When the blood clot pressure is greater than the air pressure of the other side of the third check valve 59, the third check valve 59 opens, and the blood clot flows from the internal channel into the blood clot collection bag connected to the suction pump 50.

[0071] The sealing sheet 58 may be made of rubber, and the one-way valve may be a spring-loaded one-way valve.

[0072] The first opening 52 and the second opening 54 are respectively disposed on opposite sides of the housing 51 .

[0073] A partition 62 is fixedly installed in the shell 51 to divide the cavity into two parts. A fourth opening 63 connected to the third opening 57 is opened on the partition 62. The sealing sheet 58 is located between the partition 62 and the second opening 54. When the first handle 60 and the second handle 61 are released, the sealing sheet 58 can be against the partition 62.

[0074] In order to facilitate the operation of the first handle 60 and the second handle 61, the first handle 60 is formed with a bending portion 64 bent toward the second handle 61, so that when the first handle 60 and the second handle 61 are squeezed, the bending portion 64 can better drive the second handle 61 to move, and then drive the piston 56 to move.

[0075] The bolt-breaking device includes one or more of a first bolt-breaking component, a second bolt-breaking component, a third bolt-breaking component, and a fourth bolt-breaking component. These bolt-breaking components can be used in conjunction with the suction catheter 10 as needed.

[0076] like Figure 5 Shown is a first thrombus-breaking assembly, which includes a first catheter 71, a first second catheter 72 slidably sleeved outside the first catheter 71, and a first agitator arranged at the distal end of the first catheter 71 and having an open state and a folded state; the first agitator includes a plurality of baskets 73 arranged in sequence along the axis of the first catheter 71, and the maximum diameters of the plurality of baskets 73 in the open state decrease successively from the distal end to the proximal end, so that the first agitator can be better applied to the bifurcation of the pulmonary artery and the capillary.

[0077] The first agitator is woven. The plurality of mesh baskets 73 are flat in the open state, and the inner diameter of each mesh basket 73 along the radial direction of the first conduit 71 is larger than the inner diameter along the axial direction of the first conduit 71. A connecting component 74 is provided between two adjacent mesh baskets 73. In this embodiment, the mesh basket 73 and the connecting component 74 can be woven as one piece.

[0078] During use, the first agitator is retracted into the first-second catheter 72. The first-second catheter 72 is first passed through the thrombus site, and then the first-second catheter 72 is withdrawn, so that the first agitator automatically expands, so that the thrombus adheres to the basket 73, and the thrombus can be better broken up by dragging the first-first catheter 71 back and forth. Then the first agitator is retracted into the first-second catheter 72, and the suction catheter 10 is withdrawn.

[0079] like Figure 6 Shown is a second plug-breaking assembly, which includes a second-first conduit 81, a second-second conduit 82 slidably sleeved outside the second-first conduit 81, and a second agitator 83 arranged at the far end of the second-first conduit 81 and having an open state and a retracted state; the second agitator 83 is linear and curved when in the open state.

[0080] The second agitator 83 may be a guide wire, or a linear or tubular material such as a catheter, and the curved shape may be a sine wave, or a spiral shape.

[0081] During use, the second agitator 83 is retracted in the second catheter 82. The second catheter 82 is first passed through the thrombus site, and then the second catheter 82 is withdrawn to allow the second agitator 83 to expand automatically. The thrombus is then broken up by rotating the second agitator 83. After the operation is completed, the second agitator 83 is retracted in the second catheter 82, and the suction catheter 10 is then withdrawn.

[0082] like Figure 7 Shown is a third plug-breaking assembly, which includes a third-first catheter 91, a third-second catheter 92 slidably sleeved outside the third-first catheter 91, and a third agitator 93 arranged at the far end of the third-first catheter 91 and having an open state and a retracted state; the third agitator 93 is sheet-shaped and is curved when in the open state.

[0083] The third agitator 93 can be a spiral diaphragm formed by materials such as polyurethane or PTFE. The sheet structure can expand the contact area between the third agitator 93 and the thrombus during rotation, thereby breaking up the thrombus and quickly opening the blood vessel during rotation.

[0084] The second plug-breaking assembly and the third plug-breaking assembly also include a motor connected to the proximal end of the second catheter 81 or the proximal end of the third catheter 91 and capable of driving the second agitator 83 or the third agitator 93 to rotate around its own axis. The motor can control the rotation speed of the second agitator 83 and the third agitator 93 to be 0 to 6000 r / min.

[0085] During use, the third agitator 93 is retracted in the third-second catheter 92. The third-second catheter 92 is first passed through the thrombus site, and then the third-second catheter 92 is withdrawn to allow the third agitator 93 to expand automatically. Then, the second agitator 83 is rotated to break up the thrombus. After the operation is completed, the third agitator 93 is retracted in the third-second catheter 92, and then the suction catheter 10 is withdrawn.

[0086] like Figure 8 The fourth plug breaking assembly is shown, which includes a fourth first catheter 101, a fourth second catheter 102 slidably sleeved outside the fourth first catheter 101, and a fourth agitator arranged at the distal end of the fourth first catheter 101 and having an open state and a retracted state. The distal end of the fourth first catheter 101 extends out of the fourth second catheter 102; the fourth agitator includes a plurality of wires 103; the distal end of each wire 103 is fixedly connected to the fourth first catheter 101, and the proximal end is fixedly connected to the fourth second catheter 102; and at least some of the wires 103 intersect; at least some of the wires 103 rotate around the fourth first catheter 101 at a certain angle; the material of the wires 103 is one or more of nickel-titanium alloy, stainless steel wire, and high molecular polymer. When the fourth-first catheter 101 moves toward the proximal end relative to the fourth-second catheter 102, the fourth agitator is opened, and as the moving distance of the fourth-first catheter 101 is longer, the fourth agitator expands more and the outer diameter of the fourth agitator increases; when the fourth-first catheter 101 moves toward the distal end relative to the fourth-second catheter 102 until the wire 103 is straightened, the fourth agitator is in a retracted state, at which time the outer diameter of the fourth agitator is the smallest and basically fits on the fourth-first catheter 101.

[0087] The rotation angle of the wire 103 around the fourth conduit 101 can be determined according to the length of the wire 103 and the maximum outer diameter required when the agitator is in the open state.

[0088] Further preferably, the proximal end of the fourth catheter 101 is provided with an injection hole for injecting thrombolytic drugs such as urokinase, recombinant streptokinase, recombinant plasminogen activator, etc., and the distal end of the fourth catheter 101 and / or the silk thread 103 are formed with a plurality of thrombolytic holes 104 for the thrombolytic drugs to enter the blood vessels.

[0089] The steps of performing surgery using this thrombus management platform are as follows:

[0090] 1. First, send the guide wire to the designated position;

[0091] 2. Send the suction catheter 10 and the dilator into the lesion and withdraw the dilator;

[0092] 3. Push any embolic breaking device along the guide wire through the suction catheter 10 to the front end of the lesion, use the embolic breaking device to break the embolism, then repeatedly squeeze the suction pump 50 to generate negative pressure, and withdraw the embolic breaking device at the same time;

[0093] 4. If necessary, other embolus breaking devices can be pushed into the lesion site for further treatment, and after the operation is completed;

[0094] 5. Adjust the angle of the suction catheter 10 to aspirate the embolus again;

[0095] 6. After the operation is completed, withdraw the suction catheter 10.

[0096] The present invention can achieve a good thrombus removal effect while not blocking blood flow in the blood vessels during the operation. The present invention can be applied to the pulmonary artery, especially the bifurcation between the pulmonary artery and the capillaries, the blood loss can be controlled, the operation steps are simple, the operation time is shortened, and the hospitalization expenses of the patient are reduced.

[0097] As mentioned above, we have described the invention in full accordance with the purpose of the invention, but the invention is not limited to the above embodiments and implementation methods. Practitioners in the relevant technical field can make different changes and implementations within the scope permitted by the technical concept of the invention.

Claims

1. A pulmonary artery thrombosis treatment platform, comprising a suction catheter (10) having a suction channel, characterized in that: The thrombus treatment platform further comprises a thrombus breaking device and a suction pump (50) connected to the proximal end of the suction catheter (10); The bolt-breaking device includes one or more of a first bolt-breaking assembly, a second bolt-breaking assembly, and a third bolt-breaking assembly; The first plug-breaking assembly comprises a first first conduit (71), a first second conduit (72) slidably sleeved outside the first first conduit (71), and a first agitator arranged at the distal end of the first first conduit (71) and having an open state and a closed state; the first agitator comprises a plurality of net baskets (73) arranged in sequence along the axis of the first first conduit (71), and the maximum diameters of the plurality of net baskets (73) in the open state decrease in sequence from the distal end to the proximal end; The second plug-breaking assembly comprises a second first conduit (81), a second second conduit (82) slidably sleeved outside the second first conduit (81), and a second agitator (83) disposed at the distal end of the second first conduit (81) and having an open state and a retracted state; the second agitator (83) is linear and curved in the open state; The third plug-breaking assembly comprises a third first conduit (91), a third second conduit (92) slidably sleeved outside the third first conduit (91), and a third agitator (93) arranged at the distal end of the third first conduit (91) and having an open state and a retracted state; the third agitator (93) is in a sheet shape and is in a curved shape when in the open state; The second plug-breaking assembly and / or the third plug-breaking assembly further comprises a motor connected to the proximal end of the second first conduit (81) or the proximal end of the third first conduit (91) and capable of driving the second agitator (83) or the third agitator (93) to rotate around its own axis; The suction catheter (10) comprises a catheter portion having the suction channel, an operating portion movably connected to the proximal end of the catheter portion, a fixing member (15) fixedly arranged on the catheter portion, a connecting member respectively connected to the operating portion and the fixing member (15) and capable of bending the distal end of the catheter portion by operating the operating portion, and a developing ring (5) fixedly arranged at the distal end of the catheter portion; The operating part comprises a first operating part (41) movably connected to the proximal end of the catheter part, and a second operating part (42) movably connected to the proximal end of the catheter part, and the connecting member comprises a first connecting member (21) and a second connecting member (22); the first connecting member (21) and the second connecting member (22) respectively have two distal end portions located at the distal end and a portion located at the proximal end, the two distal end portions of the first connecting member (21) are respectively arranged on opposite sides of the catheter part, and the proximal end of the first connecting member (21) is wound around the first operating part (41); the two distal end portions of the second connecting member (22) are respectively arranged on opposite sides of the catheter part, and the proximal end of the second connecting member (22) is wound around the second operating part (42); and the two distal ends of the first connecting member (21) and the two distal ends of the second connecting member (22) are evenly distributed along the circumference of the catheter part; when the first operating member (41) and the second operating member (42) are operated, the front end of the catheter part can be directional and rotated in three-dimensional space.

2. A pulmonary artery thrombosis treatment platform, comprising a suction catheter (10) having a suction channel, characterized in that: The thrombus treatment platform further comprises a thrombus breaking device and a suction pump (50) connected to the proximal end of the suction catheter (10); The bolt-breaking device includes one or more of a first bolt-breaking assembly, a second bolt-breaking assembly, and a third bolt-breaking assembly; The first plug-breaking assembly comprises a first conduit (71) passing through the suction channel, a first second conduit (72) passing through the suction channel and slidably sleeved outside the first conduit (71), and a first agitator arranged at the distal end of the first conduit (71) and having an open state and a closed state; the first agitator comprises a plurality of net baskets (73) arranged in sequence along the axis of the first conduit (71), and the maximum diameters of the plurality of net baskets (73) in the open state decrease in sequence from the distal end to the proximal end; when the first agitator is in the open state, the first agitator extends out of the distal end of the suction conduit (10); The second plug-breaking assembly comprises a second first conduit (81) passing through the suction channel, a second second conduit (82) passing through the suction channel and slidably sleeved outside the second first conduit (81), and a second agitator (83) arranged at the distal end of the second first conduit (81) and having an open state and a retracted state; the second agitator (83) is linear and curved in the open state; when the second agitator (83) is in the open state, the second agitator (83) extends out of the distal end of the suction conduit (10); The third plug-breaking assembly comprises a third first conduit (91) passing through the suction channel, a third second conduit (92) passing through the suction channel and slidably sleeved outside the third first conduit (91), and a third agitator (93) arranged at the distal end of the third first conduit (91) and having an open state and a retracted state; the third agitator (93) is in a sheet shape and is in a curved shape when in the open state; when the third agitator (93) is in the open state, the third agitator (93) extends out of the distal end of the suction conduit (10); The second plug-breaking assembly and / or the third plug-breaking assembly further comprises a motor connected to the proximal end of the second first conduit (81) or the proximal end of the third first conduit (91) and capable of driving the second agitator (83) or the third agitator (93) to rotate around its own axis; The suction catheter (10) comprises a catheter portion having the suction channel, an operating portion movably connected to the proximal end of the catheter portion, a fixing member (15) fixedly arranged on the catheter portion, a connecting member respectively connected to the operating portion and the fixing member (15) and capable of bending the distal end of the catheter portion by operating the operating portion, and a developing ring (5) fixedly arranged at the distal end of the catheter portion; The operating part comprises a first operating part (41) movably connected to the proximal end of the catheter part, and a second operating part (42) movably connected to the proximal end of the catheter part, and the connecting member comprises a first connecting member (21) and a second connecting member (22); the first connecting member (21) and the second connecting member (22) respectively have two distal end portions located at the distal end and a portion located at the proximal end, the two distal end portions of the first connecting member (21) are respectively arranged on opposite sides of the catheter part, and the proximal end of the first connecting member (21) is wound around the first operating part (41); the two distal end portions of the second connecting member (22) are respectively arranged on opposite sides of the catheter part, and the proximal end of the second connecting member (22) is wound around the second operating part (42); and the two distal ends of the first connecting member (21) and the two distal ends of the second connecting member (22) are evenly distributed along the circumference of the catheter part; when the first operating member (41) and the second operating member (42) are operated, the front end of the catheter part can be directional and rotated in three-dimensional space.

3. The pulmonary artery thrombosis treatment platform according to claim 1 or 2, characterized in that: The multiple baskets (73) are flat in an open state, and the inner diameter of each basket (73) along the radial direction of the first conduit (71) is larger than the inner diameter along the axial direction of the first conduit (71).

4. The pulmonary artery thrombosis treatment platform according to claim 1 or 2, characterized in that: A connecting component (74) is provided between two adjacent mesh baskets (73).

5. The pulmonary artery thrombosis treatment platform according to claim 1 or 2, characterized in that: The first agitator is formed by weaving.

6. The pulmonary artery thrombosis treatment platform according to claim 1 or 2, characterized in that: The suction pump (50) comprises a housing (51) having an internal cavity, a first opening (52) arranged on the housing (51) and capable of communicating with the suction conduit (10), a first one-way valve (53) arranged at the first opening (52) and capable of closing the first opening (52), a second opening (54) arranged on the housing (51) and capable of communicating with the outside, a second one-way valve (55) arranged at the second opening (54) and capable of closing the second opening (54), a piston (56) slidably arranged in the housing (51) and having an internal passage, a sealing sheet (58) fixedly arranged on the piston (56) and having a third opening (57) communicating with the internal passage, a third one-way valve (55) arranged at the third opening (57) and capable of closing the third opening (57), and a sealing sheet (58) fixedly arranged on the piston (56) and having a third opening (57) communicating with the internal passage. A valve (59), a first handle (60) rotatably connected to the housing (51), and a second handle (61) rotatably connected to the piston (56) and capable of driving the piston (56) to slide; the first handle (60) and the second handle (61) are rotatably connected, and the sealing plate (58) is located between the first opening (52) and the second opening (54); when the first handle (60) and the second handle (61) are operated to make the sealing plate (58) move toward the second opening (54), the first opening (52) is opened and the second opening (54) is closed; when the sealing plate (58) moves toward the first opening (52), the first opening (52) is closed; when the thrombus pressure in the internal cavity is greater than the air pressure, the third opening (57) is opened.

7. The pulmonary artery thrombosis treatment platform according to claim 6, characterized in that: A partition (62) is fixedly disposed in the shell (51) to divide the cavity into two parts, and a fourth opening (63) connected to the third opening (57) is provided on the partition (62), and the sealing sheet (58) is located between the partition (62) and the second opening (54).

8. The pulmonary artery thrombosis treatment platform according to claim 6, characterized in that: The first handle (60) is formed with a bent portion (64) bent in a direction toward the second handle (61).

9. The pulmonary artery thrombosis treatment platform according to claim 1 or 2, characterized in that: The outer diameter of the suction catheter (10) is 6F to 14F.

10. The pulmonary artery thrombosis treatment platform according to claim 1 or 2, characterized in that: The bolt-breaking device also includes a fourth bolt-breaking assembly, which includes a fourth-first catheter (101), a fourth-second catheter (102) slidably mounted outside the fourth-first catheter (101), and a fourth agitator arranged at the distal end of the fourth-first catheter (101) and having an open state and a retracted state; the distal end of the fourth-first catheter (101) extends out of the fourth-second catheter (102); the fourth agitator includes a plurality of silk threads (103); the distal end of each of the silk threads (103) is fixedly connected to the fourth-first catheter (101), and the proximal end is fixedly connected to the fourth-second catheter (102); and at least some of the silk threads (103) intersect; at least some of the silk threads (103) rotate around the fourth-first catheter (101) at a certain angle; the material of the silk threads (103) is one or more of nickel-titanium alloy, stainless steel wire, and high molecular polymer.

11. The pulmonary artery thrombosis treatment platform according to claim 10, characterized in that: The proximal end of the fourth first catheter (101) is provided with an injection hole for injecting thrombolytic drugs, and the distal end of the fourth first catheter (101) and / or the silk thread (103) are formed with a plurality of thrombolytic holes (104) for the thrombolytic drugs to enter the blood vessels.

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