Thrombolytic catheter device with protective structure

Abstract

The present invention provides a thrombolytic catheter device with a protective structure, which relates to the technical field of medical devices. It includes a thrombolytic catheter body, a blocking guidewire and a protective umbrella, wherein the thrombolytic catheter body is sleeved outside the blocking guidewire; the protective umbrella can be folded and accommodated in the thrombolytic catheter body and connected to the blocking guidewire, and the blocking guidewire is used to push the protective umbrella outside the thrombolytic catheter body, and the protective umbrella outside the thrombolytic catheter body is restored to an unfolded state, and in the unfolded state, the radial size of the protective umbrella is greater than the radial size of the thrombolytic catheter body. The present invention can accommodate the protective umbrella into the thrombolytic catheter through the deformation of the protective umbrella, without affecting the implantation of the guide wire and the intubation of the thrombolytic catheter body. After the thrombolytic catheter is placed in the affected area, the blocking guidewire can be used to push the protective umbrella to open, and then the filtering function of the protective umbrella is used to filter the peripheral arterial embolism, so as to prevent the large plaque embolus from blocking the distal end of the blood vessel during the thrombolysis process, and avoid downstream tissue necrosis.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a thrombolytic catheter device with a protective structure. Background Art

[0002] At present, conventional treatments for thrombosis include anticoagulant therapy, surgical treatment and catheter-directed thrombolysis. Among them, the mechanism of catheter-directed thrombolysis is to directly infuse high-concentration thrombolytic drugs around the thrombus through a thrombolytic catheter to dissolve the thrombus and achieve the purpose of treatment.

[0003] When using thrombolytic catheters to treat peripheral arterial embolism, especially when the lesion is severely calcified, large plaque emboli may fall off from the lesion, block downstream blood vessels, and cause downstream tissue necrosis. To solve this problem, the existing practice is to puncture the downstream blood vessels of the embolism site separately and then place a distal protection structure independently. This operation is not only time-consuming and labor-intensive, but also increases the cost of additional surgical instruments. Summary of the invention

[0004] The purpose of the present invention is to provide a thrombolytic catheter device with a protective structure to solve the problems of inconvenience in operation, increased labor costs and increased equipment costs caused by the need for separate puncture and placement of a protective umbrella in existing thrombolytic catheter treatment.

[0005] In order to solve the above technical problems, the present invention first provides a thrombolytic catheter device with a protective structure, and the specific technical solution is as follows:

[0006] A thrombolytic catheter device with a protective structure comprises a thrombolytic catheter body and an occluding guidewire, wherein the thrombolytic catheter body is sleeved outside the occluding guidewire; and further comprises a protective umbrella for filtering thrombi, wherein the protective umbrella can be folded and accommodated in the thrombolytic catheter body and connected to the occluding guidewire, wherein the occluding guidewire is used to push the protective umbrella outside the thrombolytic catheter body, and the protective umbrella outside the thrombolytic catheter body returns to an expanded state, wherein in the expanded state, the radial dimension of the protective umbrella is greater than the radial dimension of the thrombolytic catheter body.

[0007] Furthermore, the protective umbrella includes a sleeve, a frame and a filter; the sleeve is sleeved on the blocking guide wire; the frame is installed on the sleeve and is made of an elastic deformable material; the filter is laid on the frame.

[0008] Further, the frame includes a first support member, a second support member and a third support member; one end of a plurality of the first support members is installed at one end of the sleeve at intervals along the circumference of the sleeve, and the first support member is provided with a first bending portion; the second support member is annular, and the second support member is provided with a plurality of second bending portions and a third bending portions staggered along its circumference, and the second bending portions are movably connected with the other ends of the plurality of the first support members in a one-to-one correspondence; one end of a plurality of the third support members is installed at the other end of the sleeve at intervals along the circumference of the sleeve, and the other ends of the plurality of the third support members are movably connected with the plurality of the third bending portions in a one-to-one correspondence, and the third support member is provided with a fourth bending portion.

[0009] Furthermore, a first developing ring is provided on an outer wall of one end of the sleeve.

[0010] Furthermore, the protective umbrella is movably mounted on the blocking guide wire and can move along the length direction of the blocking guide wire under the action of external force.

[0011] Furthermore, a first connecting piece is installed on the occluding guide wire, and a second connecting piece is provided on the protective umbrella. The first connecting piece is inserted into the second connecting piece, and the second connecting piece can rotate on the first connecting piece and move in the length direction of the first connecting piece.

[0012] Furthermore, a second developing ring is provided on the outer wall of the second connecting member.

[0013] Furthermore, the first connecting member includes a connecting tube and a plug that are integrally connected, and the connecting tube is fixedly connected to the occluding guide wire; a slot is provided on the inner wall of the second connecting member along its circumference, and the plug is inserted into the slot, and the length of the plug is smaller than the length of the slot; a radial dimension of an end of the plug close to the connecting tube is larger than a radial dimension of the connecting tube, and in the length direction of the slot, an end of the slot close to the connecting tube limits the end of the plug close to the connecting tube.

[0014] Furthermore, the first connecting member is provided with a plurality of notches along its circumference, and the notches are provided from an end of the plug away from the connecting pipe to a middle portion of the connecting pipe.

[0015] Furthermore, a sealing portion is provided on the blocking guidewire, and a sealing boss which seals with the blocking portion is provided on the inner wall of the thrombolytic catheter body.

[0016] According to the thrombolytic catheter device with a protective structure provided by the present invention, a protective umbrella is added on the basis of the existing thrombolytic catheter. The protective umbrella can be stored in the thrombolytic catheter through deformation, which does not affect the implantation and intubation of the guide wire. After the thrombolytic catheter is placed in the affected area, the blocking guide wire is used to push the protective umbrella to open, and then the filtering function of the protective umbrella is used to filter the peripheral arterial embolism, thereby preventing large plaque emboli from blocking the distal end of the blood vessel during the thrombolytic process and avoiding downstream tissue necrosis. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0018] Figure 1 A schematic diagram of a portion of the structure of a thrombolytic catheter device with a protective structure provided by an embodiment of the present invention;

[0019] Figure 2 A schematic diagram of the structure of a protective umbrella provided by an embodiment of the present invention;

[0020] Figure 3 for Figure 2 AA section view;

[0021] Figure 4 A schematic structural diagram of a frame of a protective umbrella provided by an embodiment of the present invention;

[0022] Figure 5 A schematic diagram of an occlusion guidewire and its upper structure provided in an embodiment of the present invention;

[0023] Figure 6 A schematic structural diagram of a first connecting member provided in an embodiment of the present invention.

[0024] icon:

[0025] 100-occluding guide wire; 110-wire winding part; 120-occluding part;

[0026] 200-first connecting piece; 210-connecting pipe; 220-plug; 230-notch;

[0027] 300-protective umbrella; 310-sleeve; 320-frame; 321-first support member; 3211-first curved portion; 322-second support member; 3221-second curved portion; 3222-third curved portion; 323-third support member; 3231-fourth curved portion; 330-filter; 340-first developing ring; 350-second connecting member; 351-slot; 360-second developing ring. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings here can be arranged and designed in various different configurations.

[0029] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0030] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, or the positions or positional relationships in which the product of the invention is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third", etc. are only used to distinguish the description, and cannot be understood as indicating or implying relative importance.

[0031] In addition, the terms "horizontal", "vertical", "overhanging" and the like do not mean that the components are required to be absolutely horizontal or overhanging, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0032] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0033] Some embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other.

[0034] Based on the description in the background technology, it can be known that the existing thrombolytic catheter and protective structure are both separate individual structures, and there is no connection between the two. Therefore, during the operation, if the protective structure is needed, it is necessary to puncture and install the protective structure separately, which wastes manpower and material resources and increases the cost of the operation. In view of this, the present embodiment proposes a thrombolytic catheter device with a protective structure, which aims to solve the above-mentioned problem by integrating the protective structure with the structure of the thrombolytic catheter.

[0035] First, combine with Figure 1 As shown, the thrombolytic catheter device with a protective structure of the present embodiment includes a thrombolytic catheter body, a connector, an occluding guidewire 100, a first connecting piece 200 and a protective umbrella 300. The thrombolytic catheter body of the present embodiment is generally made of polymer material, and a wire winding portion 110 is provided at one end of the occluding guidewire 100 away from the connector. During surgery, the thrombolytic catheter body of the present embodiment is sleeved outside the occluding guidewire 100, and one end of the thrombolytic catheter body is connected to the connector. The connector of the present embodiment is a Luer connector, which is used to connect to an external device, and a drug solution is injected into the Luer connector through the external device, and the drug solution enters the thrombolytic catheter body through the Luer connector. Since the connector and the thrombolytic catheter body are structures well known to those skilled in the art, the present embodiment does not provide specific drawings and structural descriptions for the two. In addition, the occluding guidewire 100 of the present embodiment also only shows a partial structure.

[0036] Different from the existing thrombolytic catheter, the thrombolytic catheter of this embodiment includes a protective umbrella 300 for filtering thrombus. The protective umbrella 300 is the "protective structure" described in this embodiment and the background technology, or is called a protective device. The protective umbrella 300 of this embodiment is installed at one end (i.e., the proximal end) of the occluding guide wire 100 close to the wire winding portion 110; and the protective umbrella 300 of this embodiment is constructed as follows: the protective umbrella 300 is in an expanded state under normal conditions, and can be deformed to a contained state under the action of external force.

[0037] Specifically, the radial dimension of the deployed protective umbrella 300 is larger than the radial dimension of the thrombolytic catheter body, and the filtering function of the protective umbrella 300 is used to filter the peripheral arterial embolism, thereby preventing large plaque emboli from blocking the distal end of the blood vessel during the thrombolytic process and avoiding downstream tissue necrosis; and, the radial dimension of the housed protective umbrella 300 is less than or equal to the radial dimension of the thrombolytic catheter body.

[0038] During the operation, the protective umbrella 300 of the present embodiment is first compressed and folded into the thrombolytic catheter body. The thrombolytic catheter body with the protective umbrella 300 enters the target area under the guidance of the guide wire (not shown in the figure), and then the guide wire is withdrawn and the blocking guide wire 100 of the present embodiment is inserted. The distal end (the end away from the connector) of the thrombolytic catheter body is blocked by the blocking guide wire 100 of the present embodiment, and the protective umbrella 300 is pushed out of the thrombolytic catheter body. The protective umbrella 300 is automatically unfolded, and then the filtering function of the protective umbrella 300 is used to filter the peripheral arterial embolism, thereby preventing large plaque emboli from blocking the distal end of the blood vessel during the thrombolytic process and avoiding downstream tissue necrosis.

[0039] Combined with Figure 2 and 3 As shown, in order to achieve the storage and deployment of the protective umbrella 300, the present embodiment improves the structure of the protective umbrella 300. The protective umbrella 300 of the present embodiment includes a sleeve 310, a frame 320 and a filter 330; the sleeve 310 is sleeved on the blocking guide wire 100, and the sleeve 310 is preferably gap-matched with the blocking guide wire 100, and a first developing ring 340 is provided at one end of the sleeve 310 of the present embodiment close to the wire winding portion 110.

[0040] The frame 320 of this embodiment is installed on the sleeve 310 and is made of elastic deformable material; the filter 330 is laid on the frame 320, and the frame 320 can drive the filter 330 to deform under the extrusion of the thrombolytic catheter body, thereby enabling the protective umbrella 300 of this embodiment to be accommodated and unfolded.

[0041] Based on the structure of the protective umbrella 300, in order to facilitate the deformation and recovery of the protective umbrella 300, the present embodiment further optimizes the structure of the frame 320. Figure 4 As shown, the frame 320 of this embodiment includes a first support member 321, a second support member 322 and a third support member 323, and the first support member 321, the second support member 322 and the third support member 323 are all made of materials that can be elastically deformed. And the outer periphery of the second support member 322 is attached with a developing spring that can be developed under an X-ray machine.

[0042] In this embodiment, there are multiple first support members 321, and one end of the multiple first support members 321 is installed at one end of the sleeve 310 along the circumference of the sleeve 310, specifically, it is installed at the end of the sleeve 310 away from the wire winding part 110, and is evenly spaced along the circumference of the sleeve 310. The first support member 321 is provided with a first bending portion 3211, so that its shape is approximately S-shaped, so as to facilitate elastic deformation under the action of external force.

[0043] The second support member 322 of the present embodiment is annular, and is mainly used to connect the first support member 321 and the third support member 323. The second support member 322 is provided with a plurality of second bends 3221 and third bends 3222 alternately arranged along its circumference, that is, there is a third bend 3222 between two second bends 3221, or there is a second bend 3221 between two third bends 3222. The second bends 3221 of the present embodiment are movably connected with the other ends of the plurality of first support members 321 in a one-to-one correspondence, and the movable connection method may be that an annular connecting buckle is provided at the other end of the second support member 322, and the second bend 3221 of the second support member 322 is passed through the connecting buckle.

[0044] The number of third support members 323 in this embodiment is also multiple, and one end of the multiple third support members 323 is installed at the other end of the sleeve 310 at intervals along the circumference of the sleeve 310. Specifically, the multiple third support members 323 are evenly spaced, and the other ends of the multiple third support members 323 of the weapon are movably connected to the above-mentioned multiple third bending portions 3222 in a one-to-one corresponding manner. The movable connection method is the same as the above-mentioned annular connecting buckle, and in order to facilitate the deformation of the third support member 323 of this embodiment, a fourth bending portion 3231 is provided on the third support member 323, so that the shape of the third support member 323 of this embodiment is approximately L-shaped.

[0045] Of course, the number and position of the bent portions of the support member in this embodiment are not limited to those described above, and may be increased or changed in position according to specific needs, as long as the protective umbrella 300 can be folded, stored and unfolded.

[0046] Based on the above structure, in order to improve the adaptability of the protective umbrella 300 of this embodiment, this embodiment also improves the installation method of the protective umbrella 300. In this embodiment, the protective umbrella 300 is movably installed on the blocking guidewire 100, and can be moved along the length direction of the blocking guidewire 100 under the action of external force. For example, the sleeve 310 of the protective umbrella 300 can be slidably installed on the blocking guidewire 100, but this structure cannot achieve good positioning of the protective umbrella 300, and the protective umbrella 300 is easy to slip off. Therefore, this embodiment makes specific structural optimization of the protective umbrella 300 and the blocking guidewire 100.

[0047] Combined with Figure 1 , 5 As shown in FIG. 6 , the first connecting member 200 of this embodiment is installed on the blocking guide wire 100, and the second connecting member 350 is provided at one end of the protective umbrella 300 away from the wire winding part 110, and the first connecting member 200 is inserted into the second connecting member 350, or the second connecting member 350 is sleeved on the first connecting member 200, and the second connecting member 350 of this embodiment can move relative to the first connecting member 200. Preferably, the second connecting member 350 of this embodiment is provided with a second developing ring 360 at one end away from the wire winding part 110, which can be understood as a part of the second connecting member 350 being developed under the irradiation of the X-ray machine.

[0048] Specifically, the first connector 200 of this embodiment includes a connecting tube 210 and a plug 220 that are integrally connected or integrally formed. The connecting tube 210 is fixedly connected to the blocking guide wire 100, and the connection method can be bonding, etc. The plug 220 is cone-shaped. The second connector 350 of this embodiment is a hollow structure with openings at both ends, and the inner wall of the second connector 350 is provided with a slot 351 along its circumference. The plug 220 is inserted into the slot 351. The length of the plug 220 is less than the length of the slot 351, and the radial dimension of the end of the plug 220 close to the connecting tube 210 is greater than the radial dimension of the connecting tube 210. In the length direction of the slot 351, the slot 351 close to the end of the connecting tube 210 limits the end of the plug 220 close to the connecting tube 210.

[0049] This structure enables the plug 220 of this embodiment to move within the range of the slot 351, and thus enables the second connecting member 350 and the protective umbrella 300 of this embodiment to move as a whole along the length direction of the first connecting member 200, thereby facilitating the adjustment of the position of the protective umbrella 300 and improving the adaptability of the protective umbrella 300 to different surgical requirements.

[0050] In order to enable the plug 220 to deform under extrusion so as to be inserted into the slot 351, and to restore its original state when fully inserted into the slot 351, so that the plug 220 can be limitedly matched with the slot 351, the first connecting member 200 of this embodiment is provided with a plurality of notches 230 along its circumference, and the notches 230 are provided from one end of the plug 220 away from the connecting tube 210 to the middle of the connecting tube 210, and the space formed by the notches 230 facilitates the deformation of the plug 220.

[0051] In addition, in order to improve the sealing between the catheter of this embodiment and the blocking guidewire 100, this embodiment also makes structural improvements to the blocking portion 120 on the blocking guidewire 100. The protective umbrella 300 of this embodiment is located between the wire winding portion 110 and the blocking portion 120. The inner wall of the thrombolytic catheter body is provided with a sealing boss (not shown in the figure) that is sealed with the blocking portion 120. The blocking portion 120 is preferably conical at both ends and cylindrical in the middle as shown in the figure, so as to cooperate with the sealing boss.

[0052] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A thrombolytic catheter device with a protective structure, comprising a thrombolytic catheter body and a blocking guidewire, wherein the thrombolytic catheter body is sleeved outside the blocking guidewire; It is characterized in that It also includes a protective umbrella for filtering thrombus, the protective umbrella can be folded and accommodated in the thrombolytic catheter body, and is connected to the blocking guidewire, the blocking guidewire is used to push the protective umbrella out of the thrombolytic catheter body, and the protective umbrella outside the thrombolytic catheter body is restored to an expanded state, and in the expanded state, the radial size of the protective umbrella is greater than the radial size of the thrombolytic catheter body; The protective umbrella comprises a sleeve, a frame and a filter; the sleeve is sleeved on the blocking guide wire; the frame is mounted on the sleeve and is made of an elastic deformable material; the filter is laid on the frame; The frame includes a first support member, a second support member and a third support member; One ends of a plurality of the first support members are installed at one end of the sleeve at intervals along the circumference of the sleeve, and the first support member is provided with a first bent portion; The second support member is annular, and is provided with a plurality of second curved portions and a third curved portion staggered along its circumference, and the other end of each of the first support members is provided with an annular connecting buckle, and the plurality of second curved portions pass through the annular connecting buckles of the plurality of first support members in a one-to-one correspondence, so that the plurality of second curved portions are movably connected with the other ends of the plurality of first support members in a one-to-one correspondence; One ends of the plurality of third support members are installed at intervals along the circumference of the sleeve on the other end of the sleeve, and the other end of each of the third support members is respectively provided with an annular connecting buckle, and the plurality of third bending portions pass through the annular connecting buckles of the plurality of third support members one by one, so that the other ends of the plurality of third support members are movably connected with the plurality of third bending portions one by one, and the third support members are provided with a fourth bending portion.

2. The thrombolytic catheter device with a protective structure according to claim 1, characterized in that: A first developing ring is disposed on the outer wall of one end of the sleeve.

3. The thrombolytic catheter device with a protective structure according to claim 1 or 2, characterized in that: The protective umbrella is movably mounted on the blocking guide wire and can move along the length direction of the blocking guide wire under the action of external force.

4. The thrombolytic catheter device with a protective structure according to claim 3, characterized in that: A first connecting piece is installed on the occluding guide wire, and a second connecting piece is provided on the protective umbrella. The first connecting piece is inserted into the second connecting piece, and the second connecting piece can rotate on the first connecting piece and move in the length direction of the first connecting piece.

5. The thrombolytic catheter device with a protective structure according to claim 4, characterized in that: A second developing ring is disposed on the outer wall of the second connecting member.

6. The thrombolytic catheter device with a protective structure according to claim 4, characterized in that: The first connecting member includes a connecting tube and a plug connected in one piece, and the connecting tube is fixedly connected to the blocking guide wire; The inner wall of the second connecting member is provided with a slot along its circumference, the plug is inserted into the slot, and the length of the plug is smaller than the length of the slot; The radial dimension of one end of the plug close to the connecting pipe is larger than the radial dimension of the connecting pipe. In the length direction of the slot, one end of the slot close to the connecting pipe limits the end of the plug close to the connecting pipe.

7. The thrombolytic catheter device with a protective structure according to claim 6, characterized in that: The first connecting member is provided with a plurality of notches along its circumference, and the notches are opened from one end of the plug away from the connecting pipe to the middle of the connecting pipe.

8. The thrombolytic catheter device with a protective structure according to claim 1 or 2, characterized in that: The blocking guide wire is also provided with a blocking portion, and the inner wall of the thrombolytic catheter body is provided with a sealing boss which is sealed with the blocking portion.

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