Microneedle lifting device

Abstract

The present invention provides a microneedle lifting device, which relates to the technical field of detection product production equipment. The microneedle lifting device includes a liquid storage assembly, a vacuum lifting base, a vacuum lifting piston and a lifting assembly; the fixed end of the lifting assembly is fixedly arranged on the liquid storage assembly through a bracket, and the output end of the lifting assembly is fixedly connected with the vacuum lifting piston; a piston hole on the vacuum lifting base penetrates through the vacuum lifting base, and a limiting plate for restricting the stroke of the vacuum lifting piston is arranged at the top of the vacuum lifting base; a forming substrate is arranged at the bottom of the piston hole, and a first microhole is formed in the forming substrate; a liquid storage tank for carrying a production solution is arranged on the liquid storage assembly, and a lifting plate is fixedly arranged at the opening of the liquid storage tank. A second microhole is formed in the lifting plate, and the diameter of the second microhole is larger than that of the first microhole; a vacuum pumping port connected to a vacuum generator is arranged on the vacuum lifting piston. The technical effect of reducing production costs is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of product production equipment detection, and more particularly to a micro-needle lifting device. Background Art

[0002] With the development of the economy and the progress of society, the health of the whole people has become an inevitability and a social consensus. Various health detections are increasingly developing towards the characteristics of being convenient to use, accurately identifying, safe and efficient, and having multiple functions in one machine. Health detection products have become important items in people's daily lives. Currently, for physiological and pharmacological tests on the human skin surface, physical tests are usually adopted.

[0003] In the prior art, the production of micro-conical skin-like molded products for physiological and pharmacological tests requires production through a mold. The existing mold needs to be first disassembled into multiple parts, and then a whole row of semi-cones are opened at the edges of each part. Then, the multiple parts are combined together, and the semi-cones at the edges of adjacent two parts are combined into a cone. However, the processing of the semi-cones on the parts is difficult, the accuracy of the whole row distance is difficult to guarantee, the alignment of the cones after the processing of the two parts is not easy, and parting surface marks are likely to be formed on the product, and the overall smoothness of the conical surface cannot be achieved, and the finished product rate is low. Therefore, the production cost of micro-conical skin-like molded products for physiological and pharmacological tests is high.

[0004] Therefore, providing a micro-needle lifting device that reduces the production cost of micro-conical skin-like molded products for physiological and pharmacological tests has become an important technical problem to be solved by those skilled in the art. Summary of the Invention

[0005] The purpose of the present invention is to provide a micro-needle lifting device to alleviate the technical problem of high production cost of micro-conical skin-like molded products for physiological and pharmacological tests in the prior art.

[0006] In a first aspect, an embodiment of the present invention provides a micro-needle lifting device, including a liquid storage assembly, a vacuum lifting base, a vacuum lifting piston, and a lifting assembly;

[0007] The vacuum lifting base is arranged on the liquid storage assembly and is hermetically connected to the liquid storage assembly;

[0008] The fixed end of the lifting assembly is fixedly arranged on the liquid storage assembly through a bracket, and the output end of the lifting assembly is fixedly connected to the vacuum lifting piston;

[0009] A piston hole adapted to the vacuum lifting piston is opened on the vacuum lifting base, the piston hole penetrates through the vacuum lifting base, and a limiting plate for restricting the stroke of the vacuum lifting piston is arranged at the top of the vacuum lifting base;

[0010] At the bottom of the piston hole, there is a forming substrate corresponding to the lifting plate, and a first micro-hole is provided on the forming substrate.

[0011] On the liquid holding assembly, there is a liquid holding tank for holding the production solution, and a lifting plate is fixedly arranged at the opening of the liquid holding tank. A second micro-hole is provided on the lifting plate, and the diameter of the second micro-hole is larger than that of the first micro-hole.

[0012] The vacuum lifting piston is provided with a vacuum pumping port connected to a vacuum generator.

[0013] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, a solution chamber piston is arranged in the above-mentioned liquid holding tank, and the solution chamber piston is slidably sealed with the liquid holding tank.

[0014] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the above-mentioned liquid holding assembly includes a base and a liquid holding substrate.

[0015] The liquid holding substrate is slidably arranged on the base, and a positioning block for positioning the liquid holding substrate is arranged on the base.

[0016] The liquid holding tank is opened on the liquid holding substrate.

[0017] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the above-mentioned micro-needle lifting device further includes a positioning assembly for positioning the liquid holding substrate.

[0018] The positioning assembly is detachably arranged on the base.

[0019] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the above-mentioned positioning assembly includes a rotary positioning handle, a positioning spring pin, a positioning rotary pin and a positioning movable block.

[0020] The positioning movable block is arranged on the base through the positioning rotary pin. The positioning spring pin is arranged on the positioning movable block. The rotary positioning handle is threadedly arranged on the positioning movable block, and the rotary positioning handle can drive the positioning spring pin to abut against the groove on the outer wall of the liquid holding substrate.

[0021] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the above-mentioned lifting assembly includes a lifting member and a lifting seat.

[0022] The lifting seat is arranged on the base through a bracket.

[0023] The lifting member is fixedly arranged on the lifting seat, and the output end of the lifting member is connected to the vacuum lifting piston.

[0024] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the above-mentioned lifting member adopts a push rod type linear screw stepper motor.

[0025] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, a transparent forming observation base is arranged between the liquid-containing substrate and the vacuum lifting base;

[0026] A sealing ring is arranged between the forming observation base and the vacuum lifting base;

[0027] A sealing ring is arranged between the forming observation base and the liquid-containing substrate.

[0028] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the diameter of the above-mentioned first micro-hole is between 0.0007 mm and 0.001 mm.

[0029] Combined with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect. Among them, the diameter of the above-mentioned second micro-hole is between 0.15 mm and 0.25 mm.

[0030] Beneficial effects:

[0031] The embodiment of the present invention provides a microneedle lifting device, including a liquid-containing component, a vacuum lifting base, a vacuum lifting piston and a lifting component; the vacuum lifting base is arranged on the liquid-containing component and the two are hermetically connected; the fixed end of the lifting component is fixedly arranged on the liquid-containing component through a bracket, and the output end of the lifting component is fixedly connected to the vacuum lifting piston; a piston hole adapted to the vacuum lifting piston is opened on the vacuum lifting base, the piston hole penetrates the vacuum lifting base, and a limiting plate for restricting the stroke of the vacuum lifting piston is arranged at the top of the vacuum lifting base; a forming substrate corresponding to the lifting plate is arranged at the bottom of the piston hole, and a first micro-hole is opened on the forming substrate; a liquid-containing groove for carrying a production solution is opened on the liquid-containing component, and a lifting plate is fixedly arranged at the opening of the liquid-containing groove, a second micro-hole is opened on the lifting plate, and the diameter of the second micro-hole is larger than that of the first micro-hole; a vacuum pumping port connected to a vacuum generator is arranged on the vacuum lifting piston.

[0032] In specific use, the staff pours the production solution into the liquid holding component, then closes the liquid holding component and the vacuum lifting base, keeping the two sealed and connected. Then, the staff turns on the vacuum generator, making the inside of the vacuum lifting piston in a vacuum state and keeping the vacuum generator working continuously. As a result, the production solution in the liquid holding component flows to the forming substrate through the lifting plate. Then, the lifting component is started, and the vacuum lifting piston is intermittently driven by the lifting component to slowly rise. Consequently, the forming substrate will pull the working solution upward, and the production solution in the liquid holding component is slowly replenished. Eventually, the production of a micro-cone-shaped skin-like formed product for physiological and pharmacological tests is completed. Then, the finished product is removed from the forming substrate. With this setting, the production cost is reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for use in the description of the specific embodiments or the prior art. Obviously, the drawings in the following description are some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0034] Figure 1 is a schematic structural diagram of a prior art mold;

[0035] Figure 2 is Figure 1 a partial enlarged view of part A in

[0036] Figure 3 is a schematic structural diagram of the micro-needle lifting device provided by the embodiment of the present invention;

[0037] Figure 4 is a top view of the micro-needle lifting device provided by the embodiment of the present invention;

[0038] Figure 5 is Figure 4 a cross-sectional view taken along A - A in

[0039] Figure 6 is Figure 4 a cross-sectional view taken along B - B in

[0040] Figure 7 is an exploded schematic diagram of the forming substrate and the lifting plate in the micro-needle lifting device provided by the embodiment of the present invention;

[0041] Figure 8 is a schematic diagram of the forming substrate and the lifting plate in the micro-needle lifting device provided by the embodiment of the present invention.

[0042] Reference Signs:

[0043] 100 - Liquid-containing assembly; 110 - Base; 111 - Positioning block; 120 - Liquid-containing substrate; 121 - Liquid-containing tank;

[0044] 200 - Vacuum lifting base; 210 - Lock; 220 - Limiting plate;

[0045] 300 - Vacuum lifting piston; 310 - Vacuum pumping port;

[0046] 400 - Lifting assembly; 410 - Bracket; 420 - Lifting member; 430 - Lifting seat;

[0047] 500 - Forming substrate; 510 - First micro-hole;

[0048] 600 - Lifting plate; 610 - Second micro-hole;

[0049] 700 - Solution chamber piston;

[0050] 800 - Positioning assembly; 810 - Rotating positioning handle; 820 - Positioning spring pin; 830 - Positioning rotating pin; 840 - Positioning movable block;

[0051] 900 - Forming observation base. Detailed implementation manners

[0052] Next, the technical solutions of the present invention will be described clearly and completely in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0053] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a limitation of the present invention.

[0054] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality" means two or more, unless otherwise specifically defined.

[0055] In the present invention, unless otherwise clearly specified and defined, terms such as "installation", "connection", "linkage", "fixation", etc. shall be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or integrated; it may be a mechanical connection or an electrical connection; it may be a direct connection or an indirect connection through an intermediate medium, and it may be the internal communication of two components or the interaction relationship between two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0056] The present invention will be further described in detail below through specific embodiments in conjunction with the accompanying drawings.

[0057] See Figure 1 - Figure 8 As shown, an embodiment of the present invention provides a microneedle lifting device, which includes a liquid storage assembly 100, a vacuum lifting base 200, a vacuum lifting piston 300, and a lifting assembly 400; the vacuum lifting base 200 is arranged on the liquid storage assembly 100 and the two are hermetically connected; the fixed end of the lifting assembly 400 is fixedly arranged on the liquid storage assembly 100 through a bracket 410, and the output end of the lifting assembly 400 is fixedly connected to the vacuum lifting piston 300; a piston hole adapted to the vacuum lifting piston 300 is provided on the vacuum lifting base 200, and the piston hole penetrates the vacuum lifting base. A limiting plate 220 for limiting the stroke of the vacuum lifting piston 300 is provided at the top of the vacuum lifting base 200; a forming substrate 500 corresponding to a lifting plate 600 is provided at the bottom of the piston hole, and a first microhole 510 is provided on the forming substrate 500; a liquid storage tank 121 for carrying a production solution is provided on the liquid storage assembly 100, and a lifting plate 600 is fixedly arranged at the opening of the liquid storage tank 121. A second microhole 610 is provided on the lifting plate 600, and the diameter of the second microhole 610 is larger than that of the first microhole 510; a vacuum extraction port 310 connected to a vacuum generator is provided on the vacuum lifting piston 300.

[0058] In specific use, the staff pours the production solution into the liquid holding component 100, then closes the liquid holding component 100 and the vacuum lifting base 200, keeping the liquid holding component 100 and the vacuum lifting base 200 sealed and connected. Then the staff turns on the vacuum generator, making the inside of the vacuum lifting piston 300 in a vacuum state and keeping the vacuum generator working continuously, so that the production solution in the liquid holding component 100 flows to the forming substrate 500 through the lifting plate 600. Then the lifting component 400 is started, and the vacuum lifting piston 300 is intermittently driven by the lifting component 400 to slowly rise, so that the forming substrate 500 will pull the working solution up, and the production solution in the liquid holding component 100 is slowly replenished. Finally, the production of a micro-cone-shaped skin-like formed product for physiological and pharmacological tests is completed, and then the finished product is removed from the forming substrate 500. With such a setting, the production cost is reduced.

[0059] Specifically, the sealing work between the liquid holding component 100 and the vacuum lifting base 200 is completed through a sealing ring. And during the preparation process, after the staff loads the production solution into the liquid holding component 100, the staff controls the lifting component 400 to lower the vacuum lifting base 200 to cooperate with the liquid holding component 100, and locks the buckle 210 arranged on the outer side walls of both the liquid holding component 100 and the vacuum lifting base 200, so as to ensure that there is no leakage in the sealed connection between the liquid holding component 100 and the vacuum lifting base 200.

[0060] Among them, it is connected to the vacuum extraction port 310 on the vacuum lifting piston 300 through the vacuum generator, so as to evacuate the inside of the vacuum lifting piston 300, that is, evacuate the space between the vacuum lifting piston 300 and the shaping substrate, so that the production solution below the lifting plate 600 fixed on the liquid holding component 100 flows into the second micropores 610 on the lifting plate 600 under the action of vacuum negative pressure, and flows along the second micropores 610 to the first micropores 510 on the shaping substrate. Then the lifting component 400 works intermittently, slowly lifting the vacuum lifting piston 300. The rising of the vacuum lifting piston 300 will drive the shaping substrate to rise synchronously, thereby pumping the production solution in the second micropores 610 of the lifting plate 600. And the lifting component 400 works intermittently to ensure that the production solution flowing out of the second micropores 610 solidifies, and the production of the formed product is completed smoothly with the work of the lifting component 400.

[0061] Among them, the size of the second micropores 610 is larger than the size of the first micropores 510, so that the pulled test product is in the shape of a micro-cone.

[0062] Among them, a limiting plate 220 is provided at the top of the vacuum lifting base 200 to limit the maximum stroke of the vacuum lifting piston 300. When the staff releases the latch 210 on the outer side walls of both the liquid holding assembly 100 and the vacuum lifting base 200, the vacuum lifting piston 300 moves to the maximum stroke, and the vacuum lifting piston 300 can drive the vacuum lifting base 200 to move upward, thereby exposing the molding substrate 500 so that the staff can remove the molded product on the molding substrate 500.

[0063] It should be noted that the diameter of the first micro-hole 510 is between 0.0007 mm and 0.001 mm. Specifically, the diameter of the first micro-hole 510 can be set to 0.008 mm.

[0064] It should also be noted that the diameter of the second micro-hole 610 is between 0.15 mm and 0.25 mm. Specifically, the diameter of the second micro-hole 610 can be set to 0.2 mm.

[0065] It should also be noted that the micro-holes on the molding substrate 500 and the lifting plate 600 can be formed by powder sintering technology.

[0066] It should be noted that the production liquid can be a skin-like solution. In addition, those skilled in the art can select the specific type of production liquid according to actual detection needs.

[0067] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, a solution chamber piston 700 is provided in the liquid holding tank 121, and the solution chamber piston 700 is slidably sealed with the liquid holding tank 121.

[0068] Specifically, a solution chamber piston 700 is provided in the liquid holding tank 121, and the solution chamber piston 700 is slidably sealed with the liquid holding tank 121. By setting the solution chamber piston 700, the vacuum generator can work stably, so that the vacuum in the vacuum lifting piston 300 remains constant. With such a setting, when the pumping and pulling assembly lifts the vacuum lifting piston 300, the solution chamber piston 700 provided in the liquid holding tank 121 will rise under the action of negative pressure, thereby squeezing the production solution in the liquid holding tank 121 to prevent the molded product from breaking during the production process.

[0069] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, the liquid holding assembly 100 includes a base 110 and a liquid holding substrate 120; the liquid holding substrate 120 is slidably provided on the base 110, and a positioning block 111 for positioning the liquid holding substrate 120 is provided on the base 110; a liquid holding tank 121 is opened on the liquid holding substrate 120.

[0070] Specifically, the liquid holding assembly 100 includes a base 110 and a liquid holding substrate 120. The liquid holding substrate 120 is slidably disposed on the base 110, and the liquid holding substrate 120 is positioned by arranging a positioning block 111 on the base 110 to ensure that the axis of the liquid holding groove 121 on the liquid holding substrate 120 coincides with the axis of the vacuum lifting piston 300.

[0071] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, the microneedle lifting device further includes a positioning assembly 800 for positioning the liquid holding substrate 120; the positioning assembly 800 is detachably disposed on the base 110.

[0072] Specifically, the liquid holding substrate 120 is positioned and adjusted by the positioning assembly 800 to ensure that the liquid holding substrate 120 is in the correct position on the base.

[0073] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, the positioning assembly 800 includes a rotary positioning handle 810, a positioning spring pin 820, a positioning rotary pin 830, and a positioning movable block 840; the positioning movable block is disposed on the base 110 through the positioning rotary pin 830, the positioning spring pin 820 is disposed on the positioning movable block 840, the rotary positioning handle 810 is threadedly disposed on the positioning movable block 840, and the rotary positioning handle 810 can drive the positioning spring pin 820 to abut against the groove on the outer wall of the liquid holding substrate 120.

[0074] During the specific use process, the staff places the liquid holding substrate 120 on the base 110, then installs the positioning movable block on the base 110 through the positioning rotary pin 830, and then the staff can rotate the rotary positioning handle 810 to drive the positioning spring pin 820, so that the end of the positioning spring pin 820 abuts against the groove on the outer wall of the liquid holding substrate 120, thereby driving the liquid holding substrate 120, so that the liquid holding substrate 120 enters the preset position and fixes the liquid holding substrate 120.

[0075] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, the lifting assembly 400 includes a lifting member 420 and a lifting seat 430; the lifting seat 430 is disposed on the base 110 through a bracket 410; the lifting member 420 is fixedly disposed on the lifting seat 430, and the output end of the lifting member 420 is connected to the vacuum lifting piston 300.

[0076] Specifically, the lifting member 420 is disposed on the lifting seat 430, the lifting seat 430 is disposed on the bracket 410, and the output end of the lifting member 420 is connected to the vacuum lifting piston 300, so that when the lifting member 420 works, it can drive the vacuum lifting piston 300 to rise or fall.

[0077] Among them, the bracket 410 is fixedly arranged on the base 110, and the bracket 410 can adopt a column.

[0078] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, the lifting member 420 adopts a push rod type linear screw stepper motor.

[0079] Specifically, the lifting member 420 can adopt a push rod type linear screw stepper motor, and the step size of the push rod type linear screw stepper motor can reach 3μm.

[0080] See Figure 3 - Figure 8 As shown, in an alternative solution of this embodiment, a transparent forming observation base 900 is arranged between the liquid containing substrate 120 and the vacuum lifting base 200; a sealing ring is arranged between the forming observation base 900 and the vacuum lifting base 200; and a sealing ring is arranged between the forming observation base 900 and the liquid containing substrate 120.

[0081] Specifically, a forming observation base 900 is arranged between the liquid containing substrate 120 and the vacuum lifting base 200, and the forming observation base 900 is transparent, so that the staff can observe the production process and specific state inside the device.

[0082] It should be noted that the size of the micro - cone - shaped skin - like formed product for physiological and pharmacological tests produced by the micro - needle lifting device provided in this embodiment is: a smooth cone - shaped formed product with a bottom diameter of 0.2mm, a height of 0.6mm, and a top diameter of 0.0008mm.

[0083] It should also be noted that through the micro - needle lifting device provided in this embodiment, 10201 micro - cone - shaped skin - like formed products for physiological and pharmacological tests can be produced in 8 hours. While according to the production by the mold in the prior art, only 625 can be realized in 3 hours, and the product forming is unstable, the surface of the cone is not round, and the yield rate is extremely low.

[0084] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A microneedle lifting device, characterized in that, Comprising: a liquid holding assembly (100), a vacuum lifting base (200), a vacuum lifting piston (300) and a lifting assembly (400); The vacuum lifting base (200) is disposed on the liquid holding assembly (100) and the two are sealingly connected; The fixed end of the lifting assembly (400) is fixedly disposed on the liquid holding assembly (100) through a bracket (410), and the output end of the lifting assembly (400) is fixedly connected to the vacuum lifting piston (300); A piston hole adapted to the vacuum lifting piston (300) is formed on the vacuum lifting base (200), the piston hole penetrates the vacuum lifting base (200), and a limiting plate (220) for limiting the stroke of the vacuum lifting piston (300) is disposed at the top of the vacuum lifting base (200); A liquid holding tank (121) for holding a production solution is formed on the liquid holding assembly (100), and a lifting plate (600) is fixedly disposed at the opening of the liquid holding tank (121); A forming substrate (500) corresponding to the lifting plate (600) is disposed at the bottom of the piston hole, and a first micro-hole (510) is formed on the forming substrate (500); A second micro-hole (610) is formed on the lifting plate (600), and the diameter of the second micro-hole (610) is larger than the diameter of the first micro-hole (510); A vacuum pumping port (310) connected to a vacuum generator is disposed on the vacuum lifting piston (300); A solution chamber piston (700) is disposed in the liquid holding tank (121), and the solution chamber piston (700) is slidably sealed with the liquid holding tank (121).

2. The microneedle lifting device according to claim 1, wherein, The liquid holding assembly (100) includes a base (110) and a liquid holding substrate (120); The liquid holding substrate (120) is slidably disposed on the base (110), and a positioning block (111) for positioning the liquid holding substrate (120) is disposed on the base (110); The liquid holding tank (121) is formed on the liquid holding substrate (120).

3. The microneedle lifting device according to claim 2, wherein Also included is a positioning assembly (800) for positioning the liquid holding substrate (120); The positioning assembly (800) is detachably disposed on the base (110).

4. The microneedle lifting device according to claim 3, characterized in that, The positioning assembly (800) includes a rotary positioning handle (810), a positioning spring pin (820), a positioning rotary pin (830) and a positioning movable block (840); The positioning movable block is disposed on the base (110) through the positioning rotary pin (830), the positioning spring pin (820) is disposed on the positioning movable block (840), the rotary positioning handle (810) is threadedly disposed on the positioning movable block (840), and the rotary positioning handle (810) can drive the positioning spring pin (820) to abut against a groove on the outer wall of the liquid holding substrate (120).

5. The microneedle lifting device according to claim 2, wherein The lifting assembly (400) includes a lifting member (420) and a lifting seat (430); The lifting seat (430) is disposed on the base (110) through a bracket (410); The lifting member (420) is fixedly arranged on the lifting base (430), and the output end of the lifting member (420) is connected to the vacuum lifting piston (300).

6. The microneedle lifting device according to claim 5, wherein, The lifting member (420) adopts a push-rod type linear screw stepper motor.

7. The microneedle lifting device according to claim 2, wherein, A transparent forming observation base (900) is arranged between the liquid-containing substrate (120) and the vacuum lifting base (200); A sealing ring is arranged between the forming observation base (900) and the vacuum lifting base (200); A sealing ring is arranged between the forming observation base (900) and the liquid-containing substrate (120).

8. The microneedle lifting device according to any one of claims 1-7, characterized in that, The diameter of the first micropore (510) is between 0.0007 mm and 0.001 mm.

9. The microneedle lifting device according to any one of claims 1-7, characterized in that, The diameter of the second micropore (610) is between 0.15 mm and 0.25 mm.

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