Liquid detection system and method

Abstract

The present invention provides a liquid detection system and method, the liquid detection system comprising a plurality of liquid chambers; a first base having a first through hole, a second opening, and a third opening; a first opening and a first group of openings arranged concentrically at the bottom end of the first base, and a second group of openings at the upper end; the liquid chambers, the second group of openings, and the first group of openings arranged above and below are sequentially connected; the first opening is connected to the second opening and the third opening via a first channel; a rotating body having a linkage portion, a rotating disk, and a rotating member extending downwardly, arranged sequentially from top to bottom and passing through the first through hole; a cavity suitable for the rotating member to extend into the lower end of the second base, the cavity being sealed from the rotating disk or the bottom end of the first base; a fifth opening connected to the cavity is provided on the second base outside the cavity; a storage device has a storage chamber, and the second opening and the third opening are respectively connected to the storage chamber. The present invention has the advantages of simple structure and automation.

Description

Technical Field

[0001] The present invention relates to liquid detection, and in particular to a system and method for mixing, conveying and detecting multiple liquids. Background Art

[0002] In various analyses, samples and multiple reagents need to be added separately to a mixing chamber, such as a test tube. These samples can be human and animal samples, such as whole blood, plasma, serum, urine, saliva, feces, cerebrospinal fluid or lavage fluid, wax-sealed tissues and slices, tissue homogenates, plants, including Chinese medicine, food ingredients, processed foods, meat, beverages and alcoholic beverages, and raw materials and semi-finished products in beverage manufacturing processes. They can also be cell culture fluids or pathogenic virus culture fluids. The types of components analyzed include minerals, inorganic substances, organic substances, nucleic acids DNA, RNA, proteins or fats. Currently, the following are common liquid mixing schemes:

[0003] 1. Use multiple pumps to deliver different types of liquids into the mixing chamber. The main disadvantages of this simple solution are:

[0004] Many pipes and pumps must be used, increasing the size and cost.

[0005] 2. Using a sequential injection platform, that is, a combination of a single pump and a multi-channel directional valve, such as patent solutions CN2008100622678 and CN2008100622682. The main disadvantages of this solution are:

[0006] The injection pump and the multi-channel directional valve are relatively expensive, which increases the cost of the device.

[0007] 3. Use a three-dimensional mobile arm to extract and mix liquids, such as patent CN2016102687953.

[0008] The main disadvantages of this solution are:

[0009] The structure is complex and requires a three-dimensional moving arm with precise movement, which has poor reliability and high device cost. In addition, the amount of liquid and reagents used is large, which increases the cost of detection. Summary of the Invention

[0010] In order to solve the deficiencies in the above-mentioned prior art solutions, the present invention provides a liquid detection system with simple structure, good reliability, automation and low cost.

[0011] The purpose of the present invention is achieved through the following technical solutions:

[0012] A liquid detection system, comprising a plurality of liquid chambers; the liquid detection system further comprising:

[0013] a first base, the first base having a first through hole, a second opening, and a third opening; a first opening and a first group of openings arranged concentrically at the bottom end of the first base, and a second group of openings at the upper end; the second group of openings arranged above and below are respectively connected to the first group of openings through mutually isolated channels in the first base; the second group of openings are adapted to communicate with the liquid chamber; and the first opening is connected to the second opening and the third opening via the first channel;

[0014] a rotating body, the rotating body comprising, arranged in order from top to bottom, a linkage portion passing through the first through hole, a rotating disk having a radius greater than the first through hole and located on the lower side of the first base, and a rotating member extending downward; the upper end of the rotating disk having a fourth opening selectively communicating with the first group of openings and the first opening when the rotating disk rotates; the rotating disk having a second channel communicating with the fourth opening and the hollow rotating member;

[0015] A second base, wherein the lower end of the second base has a cavity suitable for the rotating member to extend into, and the cavity is sealed with the rotating disk or the bottom end of the first base; the second base outside the cavity has a fifth opening connected to the cavity;

[0016] The storage device comprises a storage cavity therein, wherein the second opening and the third opening are respectively communicated with the storage cavity.

[0017] The present invention also aims to provide a time-saving and automated liquid detection method, that is, the working method of the above-mentioned liquid detection system. This invention object is achieved through the following technical solutions:

[0018] A liquid detection method, comprising the following steps:

[0019] Mixing stage: driving the linkage part to rotate, so that the fourth opening on the rotating rotating disk selectively connects to the first group of openings;

[0020] The gas in the cavity is discharged from the fifth opening, and the liquid in the liquid cavity passes through the second group of openings, the channel in the first base, the first group of openings, the fourth opening, the second channel and the hollow rotating member in sequence and enters the cavity, and the multiple liquids are mixed in the cavity;

[0021] Conveying stage: driving the linkage part to rotate, so that the fourth opening on the rotating rotating disk is connected to the first opening;

[0022] Injecting gas into the cavity through the fifth opening, the liquid in the cavity sequentially passes through the hollow rotating member, the second channel, the fourth opening, the first opening, the first channel, and the second outlet, and enters the accommodating chamber in the storage device;

[0023] Detection stage: detecting the liquid in the containing cavity.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] 1. Simple structure, small size and low cost;

[0026] The liquid chamber, the first base, the rotating body, and the second base with a cavity are integrated together, eliminating the need for bulky components such as pipelines, precise three-dimensional moving arms, and liquid pumps. The flow channels are all arranged inside the first base, the rotating body, and the second base, and the flow channels are short, significantly reducing the size of the device.

[0027] No need for a liquid pump, which not only reduces the cost of the device, but also significantly reduces the amount of liquid used, that is, reduces the operating cost;

[0028] There is no need to use complex and expensive components such as three-dimensional moving arms and multi-channel directional selector valves. Instead, they are replaced by the rotation of the rotating body and pumps (including pumps with suction functions such as air pumps, peristaltic pumps and syringes). The motor and air pump that drive the rotating body are low-priced, reducing the cost of the device.

[0029] The cavity is provided below the second base, and the fifth opening is provided at the lower end of the second base outside the cavity. The cavity and the fifth opening are connected by a channel in the second base, thereby effectively reducing the volume.

[0030] A channel is formed between the connecting piece and the first base, which is convenient to process and low in cost;

[0031] The connecting piece is conveniently and accurately fixed in the first groove, which reduces assembly costs and improves manufacturing efficiency;

[0032] The storage device is partially located in the second groove, which improves assembly accuracy and firmness, increases assembly efficiency, and reduces manufacturing costs;

[0033] 2. Automation;

[0034] The linkage part is driven by external force, so that the selected liquid is selectively extracted by negative pressure technology, and the liquid in the cavity is transported upward by positive pressure technology, realizing the automatic selection, extraction and transportation of liquid;

[0035] 3. High reliability;

[0036] No need to use complex and expensive components such as three-dimensional moving arms and multi-channel directional valves, only the rotation of the rotating body and the air pump are needed, which significantly improves reliability.

[0037] By utilizing the combination of the first portion with a larger radius and the second portion with a smaller radius of the rotating disk, the annular protrusion, the third groove, the annular groove (circular groove) and the sealing member, the isolation performance of the cavity from the outside world is improved, making the cavity a closed space, which is conducive to the extraction and transportation of liquid;

[0038] The design of the cavity's cross-sectional area being smaller at the bottom and larger at the top, as well as the design of the rotating part being close to the bottom wall of the cavity, helps to increase the height of the same volume of liquid, facilitates the clean delivery of the mixed liquid, and minimizes the residual volume;

[0039] The flexible material provided in the second groove effectively improves the sealing effect between the storage device and the first base, preventing leakage;

[0040] The inner diameters of the channel and the second opening within the first base are designed so that, when no external force, such as vacuum, acts on the cavity, the liquid in the liquid cavity connected to the first opening group cannot flow out to the first opening group by gravity alone, regardless of whether the first opening group is connected to the fourth opening, thereby effectively preventing leakage.

[0041] 4. Have safety functions;

[0042] Before leaving the factory, a safety plug is inserted into the linkage part. The plug is blocked by the wing in the groove, thereby preventing the housing from moving downward, isolating the outlet of the liquid chamber from the second set of openings. The liquid in the liquid chamber will not leak out due to the seal. When it is needed, the plug is pulled out, and the relative movement between the housing and the linkage part is unblocked. The second set of openings is inserted into the outlet of the liquid chamber, so that the second set of openings and the outlet of the liquid chamber are connected, thus providing a safety function.

[0043] The combination of the first set of grooves and the elastic portion improves the firmness of the fit between the plug-in and the closure member and prevents horizontal movement of the plug-in;

[0044] The sheet-like protrusions cover the top (and wing) of the linkage part, thus improving the aesthetics. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] The disclosure of the present invention will become more easily understood with reference to the accompanying drawings. Those skilled in the art will readily appreciate that these drawings are merely used to illustrate the technical solutions of the present invention and are not intended to limit the scope of protection of the present invention.

[0046] Figure 1 Schematic diagram of the structure of the liquid detection system of the present invention. DETAILED DESCRIPTION

[0047] Figure 1The following description describes alternative embodiments of the present invention to teach those skilled in the art how to implement and reproduce the present invention. In order to teach the technical solution of the present invention, some conventional aspects have been simplified or omitted. Those skilled in the art will understand that variations or substitutions derived from these embodiments will be within the scope of the present invention. Those skilled in the art will understand that the following features can be combined in various ways to form multiple variations of the present invention. Thus, the present invention is not limited to the following alternative embodiments, but is limited only by the claims and their equivalents.

[0048] Example 1:

[0049] Figure 1 The basic structure diagram of the liquid detection system of the embodiment of the present invention is schematically shown as follows: Figure 1 As shown, the liquid detection system includes:

[0050] Multiple liquid chambers, respectively used to hold samples, reactants, reagents, etc.;

[0051] a first base, wherein the first base has a first through hole, a first opening and a first group of openings arranged concentrically at the bottom end of the first base, and a second group of openings at the upper end, wherein the second group of openings arranged above and below are respectively connected to the first group of openings through mutually isolated channels within the first base; the second group of openings are adapted to communicate with the liquid cavity, such that a one-to-one correspondence is formed between the first group of openings and the liquid cavity; a second opening and a third opening are provided on the first base, such as at the bottom end of the first base, wherein the first opening is connected to the second opening and the third opening through a first channel;

[0052] a rotating body, the rotating body comprising, arranged in order from top to bottom, a linkage portion passing through the first through hole, a rotating disk having a radius greater than the first through hole and located on the lower side of the first base, and a rotating member extending downward; the upper end of the rotating disk having a fourth opening selectively communicating with the first group of openings and the first opening when the rotating disk rotates; a second channel within the rotating disk adapted to communicate with the fourth opening and the hollow rotating member, so that liquid is discharged from the rotating body in a forward or reverse direction through the fourth opening, the second channel within the rotating disk, and the channel within the rotating member;

[0053] A second base, wherein the lower end of the second base has a cavity suitable for the rotating member to extend into, and the cavity is sealed with the rotating disk or the bottom end of the first base; the second base outside the cavity has a fifth opening connected to the cavity, so that gas in the cavity can be extracted or injected, and the cavity is under negative pressure or positive pressure;

[0054] The storage device comprises a storage cavity therein, wherein the second opening and the third opening are respectively communicated with the storage cavity.

[0055] In order to be suitable for excitation and fluorescence detection, the storage device further includes a main body and a film attached to both sides of the main body. The main body has a accommodating cavity and a sixth opening and a seventh opening connected thereto. The sixth opening is connected to the second opening, and the seventh opening is connected to the third opening.

[0056] For the convenience of processing and assembly, the upper end of the first base further has an eighth opening connected to the first opening, a ninth opening connected to the second opening, and a tenth opening connected to the third opening; the eighth opening is connected to the ninth opening and the tenth opening respectively through a "T"-shaped or "Y"-shaped channel at the upper end of the first base.

[0057] In order to facilitate the processing and assembly of the channel, further, a "T"-shaped or "Y"-shaped channel is formed between the connecting piece and the upper end of the first base, and the groove is located on the side of the connecting piece facing the first base or the upper end of the first base.

[0058] For accurate positioning and assembly, further, the second group of openings, the eighth opening, the ninth opening, the tenth opening and the connecting piece are all located in a first groove surrounded by the annular protrusion at the upper end of the first base.

[0059] In order to accurately position and facilitate assembly, as well as to improve the sealing performance between the storage device and the first base, the second opening and the third opening are further located in a second groove, the second groove has a flexible material, and part of the storage device is located in the second groove.

[0060] The sixth opening and the seventh opening are formed in a protrusion that passes through the flexible material.

[0061] In order to fix the storage device, further, a portion of the storage device is clamped between the first base and the second base, and another portion having the accommodating cavity passes through the second base.

[0062] In order to drain the liquid in the liquid cavity as much as possible and reduce the residual, the distance between the bottom end of the rotating member and the bottom wall of the liquid cavity is less than 1 mm. From bottom to top, the cross-sectional area of ​​the liquid cavity gradually increases.

[0063] In order to improve the tightness of the fit between the second group of openings and the liquid chamber and prevent leakage, the upper ends of the second group of openings are further provided with pointed ends, suitable for extending into the liquid chamber.

[0064] In order to improve the regularity of the device and reduce the volume, the liquid detection system further includes:

[0065] a housing, wherein the housing has a passage suitable for the linkage portion to pass through, and a plurality of liquid chambers are arranged around the passage;

[0066] The cover body has a plurality of through holes, and the liquid cavity is connected with the outside through the through holes.

[0067] In order to prevent the liquid from being contaminated by the outside, the liquid detection system further includes:

[0068] The closing piece is used to close the through hole on the cover body that is in communication with part of the liquid cavity; the closing piece is connected to the cover body via a connecting portion and is formed as one piece.

[0069] In order to facilitate manual gripping, the liquid detection system further includes:

[0070] A hand-held portion is arranged on the outer wall of the shell.

[0071] In order to improve the isolation between the cavity and the outside world, so that the cavity forms a closed space (connected to the outside world when necessary), further, the bottom end of the first base has a third groove, and the first opening and the first group of openings are located in the third groove; the upper end of the second base has an annular protrusion suitable for being inserted into the third groove, and the rotating disk is located in the third groove.

[0072] In order to adopt a sealing method between the rotating disk and the cavity, the rotating disk further has a first part with a larger radius and a second part with a smaller radius from top to bottom. The second part is in the space enclosed by the annular protrusion and the second base, and the first part is blocked by the annular protrusion.

[0073] The second base above the cavity has a second through hole suitable for the rotating member to pass through, and the periphery of the second through hole has a circular groove or an annular groove; the sealing member is arranged in the circular groove or the annular groove.

[0074] The liquid detection method according to the embodiment of the present invention, that is, the working method of the liquid detection system according to the embodiment, comprises the following steps:

[0075] Mixing stage: The motor drives the linkage portion to rotate, and the fourth opening on the rotating disk selectively connects to the first group of openings. In this state, the liquid chamber is connected to the second group of openings, the first group of openings, the fourth opening, the rotating disk, the channel within the rotating member, and the cavity. However, due to the resistance of the narrow channel, the liquid cannot flow out of the liquid chamber to the first group of openings by gravity alone. At the same time, the liquid in the liquid chamber not connected to the fourth opening cannot flow out of the first group of openings by gravity alone.

[0076] The gas in the cavity is discharged from the fifth opening, and the cavity is under negative pressure; the liquid in the liquid cavity successively breaks through and passes through the second group of openings, the first base inner channel, the first group of openings, the fourth opening, the second channel, and the inner channel of the rotating member to enter the cavity; the multiple liquids are mixed in the cavity;

[0077] Conveying stage: driving the linkage part to rotate, so that the fourth opening on the rotating rotating disk is connected to the first opening;

[0078] Injecting gas into the cavity through the fifth opening, the liquid in the cavity sequentially passes through the hollow rotating member, the second channel, the fourth opening, the first opening, the first channel, and the second outlet, and enters the accommodating chamber in the storage device;

[0079] Detection stage: detecting the liquid in the containing cavity.

[0080] Example 2:

[0081] An example of application of the liquid detection system and method according to Example 1 of the present invention in fluorescent quantitative PCR.

[0082] In this application example, a cover, a shell, a first base, and a second base are arranged from top to bottom and are connected and fixed to each other by snap fastening; a cylindrical channel is provided in the shell, and a plurality of liquid chambers are arranged around the cylindrical channel; the cover and the liquid chambers enclose a closed space, and the cover has a plurality of openings, which are respectively connected to the liquid chambers; the opening of the cover corresponding to the liquid chamber containing the sample is larger, and a sealing member is provided, and the side of the sealing member facing the cover has a plurality of protrusions, which are suitable for inserting into the plurality of openings on the cover, thereby closing the openings on the cover that are connected to the liquid chambers, and isolating the liquid chambers from the outside world; the outer wall of the shell has a handle, and the outer wall of the handle has vertically arranged anti-slip protrusions;

[0083] The plug-in comprises a horizontal portion and a vertical portion, wherein the vertical portion is fixed to the end of the horizontal portion; the horizontal portion has two side portions extending in opposite positions along the length direction and having strip-shaped protrusions extending outward, such as strip-shaped protrusions at the bottom ends or middle portions of the two side portions, and the strip-shaped protrusions extend continuously or discontinuously along the length direction; the two side portions have grooves suitable for the ends of the elastic portion to be snapped into, such as vertical grooves or inclined grooves extending in the up-down direction; the horizontal portion has a portion whose width gradually decreases as it gradually moves away from the vertical portion, and the upper end of the portion has a sheet-shaped protrusion extending outward and along the length direction; the top end of the sheet-shaped protrusion has a plurality of protrusions extending perpendicular to the length direction (i.e., the width direction); the horizontal portion and the vertical portion are hollow;

[0084] The closure member has a groove extending to the linkage portion; the opposite walls of the groove have wings arranged oppositely, and the distance between the two wings is smaller than the width of the groove; the groove is suitable for the insertion of the strip-shaped protrusion, and the two wings block the strip-shaped protrusion, thereby preventing the shell from moving downward, and the horizontal portion is inserted between the two wings; the two wings respectively have a suspended elastic portion, such as an elastic portion processed on the wing, and in a free state, the distance between the two elastic portions in opposite positions is smaller than the width of the portion of the horizontal portion with the strip-shaped protrusion. When the horizontal portion is inserted into the groove of the closure member, the portion of the horizontal portion with a gradually smaller width passes between the two elastic portions, and the distance between the two elastic portions is gradually expanded, and finally is inserted into the grooves of the two side portions;

[0085] The linkage portion has two slots or through holes positioned opposite to each other, one of which is wider than the other. The ends of the horizontal portion away from the vertical portion are respectively inserted into the two slots or holes of the linkage portion: first into the slot or hole with the larger width, and then into the slot or hole with the smaller width. The plug fixed in the groove prevents the linkage portion from moving upward, and the sheet-like protrusion covers the top of the linkage portion.

[0086] The first base has a first through hole, a second opening and a third opening. The bottom end of the first base has a first opening and a first group of openings that are concentric circles around the first through hole. The upper end has a second group of openings and an eighth opening that are concentric circles around the first through hole. The upper end of the second group of openings has a pointed protrusion that is suitable for inserting into the outlet at the lower end of the liquid cavity. The first base has a plurality of mutually isolated channels for connecting the first group of openings and the second group of openings respectively, so that the first group of openings corresponds to the liquid cavity one by one and are internally connected. The inner diameter of the channel is small, so that the liquid in the liquid cavity cannot flow to the first group of outlets independently by relying solely on its own gravity. The upper end of the first base also has a ninth opening and a tenth opening. The eighth opening and the first opening are connected through the first base. The channel in the base is connected, the ninth opening is connected to the second opening through the channel in the first base, and the tenth opening is connected to the third opening through the channel in the first base; the upper end of the first base has an annular protrusion, and the second group of openings, the eighth opening, the ninth opening and the tenth opening are located in the first groove surrounded by the annular protrusion; one side of the connecting piece has a "Y"-shaped groove, which is inverted in the first groove, so that a "Y"-shaped channel isolated from the outside is formed between the eighth opening and the ninth opening and the tenth opening; the second opening and the third opening are arranged in the second groove at the lower end of the first base, and outside the rotation radius of the rotating disk, the second groove has a flexible material; the lower end of the first base has a third groove, and the first through hole is located in the third groove;

[0087] The rotating body includes a linkage portion, a rotating disk, and a hollow rotating member, the central axes of which are collinear from top to bottom; the linkage portion passes through the first through hole and is located within the cylindrical channel; the linkage portion is driven to rotate by a motor; the rotating disk includes a first portion with a larger radius and a second portion with a smaller radius, the first portion and the second portion being accommodated in a third groove; a fourth opening is provided at the upper end of the rotating disk, and a second channel is provided inside the rotating disk that communicates with the interior of the rotating member; when the rotating disk rotates, the fourth opening communicates with the first opening and the first group of openings, respectively, thereby achieving selective communication with the first opening and the first group of openings, that is, achieving selective communication between the interior of the rotating member and the liquid chamber;

[0088] The second base has a cavity at the lower end, and the cross-sectional area of ​​the cavity gradually increases from bottom to top; the second base at the upper part of the cavity has a second through hole and a circular groove surrounding the second through hole; the rubber O-ring is mounted on the rotating member and is located in the circular groove, thereby achieving a seal between the rotating member and the cavity; the outer periphery of the circular groove has an annular protrusion, the second part is located in the space surrounded by the annular protrusion and the second base, and the first part is blocked by the annular protrusion; the annular protrusion is located in the third groove, and the rotating disk is located in the space surrounded by the third groove, the annular protrusion and the second base; the rotating member extends into the cavity through the second through hole, and the distance between the bottom end of the rotating member and the bottom wall of the cavity is less than 1 mm, such as 0.5 mm; the lower end of the second base outside the cavity has a convex fifth opening, and the fifth opening has a filter membrane, and the second base has a third channel for connecting the cavity and the fifth opening;

[0089] The storage device includes a main body and a film, wherein the main body has a storage cavity, and the film is attached to both sides of the main body; the main body has a convex sixth opening and a convex seventh opening respectively connected to the storage cavity; the sixth opening and the seventh opening are inserted into the flexible material in the second groove and are connected to the second opening and the third opening;

[0090] The shell, cover, closure, first base, rotating body and second base with a cavity are all made of plastic;

[0091] The motor drives the linkage part to rotate; the air pump is connected to the fifth opening to extract the gas in the cavity or inject gas.

[0092] The liquid detection method of this application example includes the following steps:

[0093] Mixing stage: The operator presses the finger on the protrusion at the top of the sheet-like protrusion of the plug-in and drags the plug-in outward, so that the end of the elastic portion disengages from the grooves on the two sides of the plug-in, the strip-like protrusion gradually withdraws from the groove of the closure, and the plug-in gradually withdraws from the slot or hole on the linkage part; the shell is pressed downward, and the pointed second group of openings on the first base are respectively inserted into the outlets at the lower end of the liquid chamber, and the shell and the first base are buckled together;

[0094] The motor drives the linkage portion to rotate, and the fourth opening on the rotating disk selectively connects to the first group of openings. In this state, the liquid chamber is connected to the second group of openings, the first group of openings, the fourth opening, the rotating disk, the passage within the rotating member, and the cavity. However, due to the resistance of the narrow passage, the liquid cannot flow out of the liquid chamber to the first group of openings solely by gravity. Simultaneously, the liquid in the liquid chamber not connected to the fourth opening cannot flow out to the first group of openings solely by gravity.

[0095] When the air pump is working, the gas in the cavity is discharged from the third channel and the fifth opening, and the cavity is under negative pressure. The liquid in the liquid cavity sequentially breaks through and passes through the second group of openings, the channels in the first base, the first group of openings, the fourth opening, the second channel, and the channel in the rotating member to enter the cavity, thereby achieving selective extraction of multiple liquids from the liquid cavity and mixing in the cavity.

[0096] Conveying stage: the motor drives the linkage part to rotate, and through positioning, the fourth opening on the rotating rotary disk is connected to the first opening;

[0097] Gas is injected into the cavity through the fifth opening, and a positive pressure is exerted on the liquid surface in the cavity, forcing the liquid in the liquid cavity to sequentially pass through the hollow rotating member, the second channel, the fourth opening, the first opening, the first channel, and the second outlet, and enter the accommodating cavity in the storage device;

[0098] Detection stage: The light emitted by the light source enters the containing cavity and stimulates fluorescence. The detector receives the fluorescence and obtains the parameters of the sample after analysis.

[0099] Example 3:

[0100] The application example of the liquid detection system and method according to Example 1 of the present invention in fluorescent quantitative PCR is different from Example 2 in that:

[0101] 1. The bottom openings of each liquid chamber are not distributed in concentric circles, and the first group of openings are also not distributed in concentric circles.

[0102] 2. An annular groove is provided on the periphery of the second through hole, and the sealing member is located in the annular groove and is sleeved on the outside of the rotating member.

Claims

1. A liquid detection system comprising a plurality of liquid chambers; characterized in that: The liquid detection system further comprises: a first base, the first base having a first through hole, a second opening, and a third opening; a first opening and a first group of openings arranged concentrically at the bottom end of the first base, and a second group of openings at the upper end; the second group of openings arranged above and below are respectively connected to the first group of openings through mutually isolated channels in the first base; the second group of openings are adapted to communicate with the liquid chamber; and the first opening is connected to the second opening and the third opening via the first channel; a rotating body, the rotating body comprising, arranged in order from top to bottom, a linkage portion passing through the first through hole, a rotating disk having a radius greater than the first through hole and located on the lower side of the first base, and a rotating member extending downward; the upper end of the rotating disk having a fourth opening selectively communicating with the first group of openings and the first opening when the rotating disk rotates; the rotating disk having a second channel communicating with the fourth opening and the hollow rotating member; a second base, wherein the lower end of the second base has a cavity adapted for the rotating member to extend therein, the cavity being sealed from the rotating disk or the bottom end of the first base; the second base having a fifth opening outside the cavity communicating with the cavity; the cross-sectional area of ​​the cavity gradually increasing from bottom to top, and the distance between the bottom end of the rotating member and the bottom wall of the cavity being less than 1 mm; A storage device having a storage cavity therein, the second opening and the third opening being respectively connected to the storage cavity; the storage device comprising a body and films attached to both sides of the body, the body having a storage cavity and a sixth opening and a seventh opening connected thereto, the sixth opening being connected to the second opening, and the seventh opening being connected to the third opening; The rotating disk has a first portion with a larger radius and a second portion with a smaller radius from top to bottom, the second portion is located in a space surrounded by the annular protrusion and the second base, and the first portion is blocked by the annular protrusion; The second base above the cavity has a second through hole suitable for the rotating member to pass through, and the periphery of the second through hole has a circular groove or an annular groove; the sealing member is arranged in the circular groove or the annular groove.

2. The liquid detection system according to claim 1, the upper end of the first base has an eighth opening connected to the first opening, a ninth opening connected to the second opening, and a tenth opening connected to the third opening; the eighth opening is connected to the ninth opening and the tenth opening respectively through a "T"-shaped or "Y"-shaped channel at the upper end of the first base.

3. The liquid detection system according to claim 2, wherein the upper end of the first base has a first groove, a "T"-shaped or "Y"-shaped channel is formed in the first groove, and the second group of openings, the eighth opening, the ninth opening and the tenth opening are located in the first groove.

4. The liquid detection system according to claim 1, wherein the second opening and the third opening are located in a second groove having a flexible material therein, and a portion of the storage device is located in the second groove; and the sixth opening and the seventh opening are formed in a protrusion which passes through the flexible material.

5. According to the liquid detection system according to claim 1, the bottom end of the first base has a third groove, and the first group of openings is located in the third groove; the upper end of the second base has an annular protrusion suitable for being inserted into the third groove, and the rotating disk is located in the third groove.

6. A liquid detection method of a liquid detection system, characterized in that: Using the liquid detection system according to any one of claims 1 to 5, the liquid detection method comprises the following steps: Mixing stage: driving the linkage part to rotate, so that the fourth opening on the rotating rotating disk selectively connects to the first group of openings; The gas in the cavity is discharged from the fifth opening, and the liquid in the liquid cavity passes through the second group of openings, the channel in the first base, the first group of openings, the fourth opening, the second channel and the hollow rotating member in sequence and enters the cavity, and the multiple liquids are mixed in the cavity; Conveying stage: driving the linkage part to rotate, so that the fourth opening on the rotating rotating disk is connected to the first opening; Injecting gas into the cavity through the fifth opening, so that the liquid in the cavity passes through the hollow rotating member, the second channel, the fourth opening, the first opening, the first channel, and the second opening in sequence, and enters the accommodating chamber in the storage device; Detection stage: detecting the liquid in the containing cavity.

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