Rectal administration device

Abstract

Rectal administration device, comprising a rod-shaped member having a top end and a bottom end, an auxiliary member, and a drug passage for delivering drugs, the drug passage being provided with at least one drug inlet and at least one drug outlet, the auxiliary member being conformally fitted over the rod-shaped member, at least the auxiliary member entering the rectum having a lower material hardness than the rod-shaped member, the auxiliary member being provided with depressions for accommodating drugs and / or fecal matter, and at least one opening being provided in the depressions.

Description

Technical Field

[0001] The present invention relates to a rectal administration device, belonging to the technical field of medical devices. Background Art

[0002] Rectally administering lubricating and irritating drugs is a common means to deal with constipation; the most typical rectal administration device is Kaisailu. The traditional Kaisailu includes a medicine storage bottle and a medicine injection tube communicated with the medicine storage bottle. When in use, the medicine injection tube is inserted into the rectum through the human anus, and the medicine storage bottle is squeezed, and the drug enters the rectum through the opening of the medicine injection tube, softening the feces, lubricating the rectal wall, and stimulating the mucosal defecation reflex.

[0003] The anal sinus at the end of the human rectum located at the dentate line is also called the anal crypt, which is funnel-shaped and opens upward. There are usually 6 to 8 of them. There are anal glands inside the anal sinus. The secretions of the anal glands can play a role in lubricating defecation. When defecating, the depression of the anal sinus opens, and the inner wall of the anal sinus contacts the feces. When the human body has constipation symptoms, the anal glands no longer secrete lubricating fluid normally, and the inside of the anal sinus is dry. After its depression opens, the inner wall of the anal sinus contacts the dry feces, increasing the friction between the feces and the anal canal wall, affecting the smooth discharge of feces. Moreover, the anatomical characteristics of the anal sinus make it easy for feces and foreign bodies to accumulate in it. Once infected by bacteria, its inflammatory substances are difficult to drain smoothly. The inflammation of the anal sinus often stimulates the anal sphincter, causing spasm to induce constipation and can lead to local ischemia. When the traditional Kaisailu medicine injection tube does not fully lubricate the anal canal wall and its internal structure, the defecation effect is poor. When feces accumulate in the anal sinus, it can cause poor excretion of anal gland secretions, a large number of bacteria multiply, becoming the main infection source of anorectal surgical diseases, and having a certain association with the occurrence of anorectal cancer; secondly, because there are many folds in the rectal wall, the medicine injection tube of the traditional Kaisailu can only transport the drug into the rectum, but cannot evenly apply the drug to the rectal wall. Therefore, the area of the rectal wall lubricated by the drug is very limited, resulting in a poor lubricating effect on the rectal wall. Especially for patients with intractable constipation, its defects are more obvious; in addition, for constipation caused by reasons such as mental tension and too little activity, defecation can be promoted by dilating and stimulating the anus and rectum. The traditional Kaisailu medicine injection tube is a smooth thin tube with no obvious change in inner diameter, which is not enough to play the role of dilating and stimulating the anus and rectum wall; for patients with diarrhea, the soft and loose feces retained in the rectal mucosa and the inside of the anal sinus are not easy to discharge, and the bacteria, viruses, parasites, etc. in it are more likely to cause inflammatory irritation, resulting in excessive bacterial reproduction, intestinal transport function defects, intestinal motility disorders, accompanied by symptoms such as tenesmus and abdominal pain. The smooth thin tube of the traditional Kaisailu entering the rectum cannot effectively remove the retained feces, etc. from the body.

[0004] In order to solve the defects of the traditional rectal administration device, it is urgent to develop a rectal administration device that can be smoothly inserted into the rectal part of the human body, clean the anal sinus, lubricate the anus and rectum wall, stimulate the defecation reflex, and effectively remove the feces, inflammatory secretions, foreign bodies, etc. retained in the anal sinus and the anal canal and rectal mucosa from the body. Summary of the Invention

[0005] In order to solve the above problems, the present invention provides a rectal administration device that can effectively wipe and remove feces, inflammatory secretions, foreign bodies, etc. remaining in the anal sinus and rectal mucosa and move them out of the body.

[0006] The object of the present invention is achieved as follows:

[0007] The rectal administration device includes a rod-shaped component with a top end and a bottom end, an auxiliary component, and a drug channel for delivering drugs. The drug channel is provided with at least one drug inlet and at least one drug outlet. The auxiliary component is conformally fitted on the rod-shaped component. At least the part of the auxiliary component that enters the rectum has a lower hardness than the rod-shaped component. The auxiliary component is provided with depressions that can accommodate drugs and / or fecal substances, and at least one opening is provided on the depressions; each of the rod-shaped component and the auxiliary component can be a single part or composed of multiple parts.

[0008] The depression can be a simple depression, or a bag-shaped one with an opening formed by partially covering the depression, or a bag-shaped one formed by partially covering the non-depressed area of the auxiliary component.

[0009] In order to fully clean the anal sinus and rectal mucosa, the auxiliary component is provided with depressions including linear, water droplet-shaped, scattered dot-shaped, serrated, bead-shaped, ring-shaped, wrinkled, terraced, bag-shaped, continuous spiral-shaped, etc. whose opening directions are the same as or intersect with the longitudinal axis direction of the rod-shaped component.

[0010] In order to more effectively stimulate and massage the anorectal wall and clean and remove feces, foreign bodies, etc. remaining inside the anal sinus and move them out of the body, the outer surface of the auxiliary component is further provided with protrusions including cord-shaped, nail-shaped, boss-shaped, hook-shaped, water droplet-shaped, cross-striped, scattered dot-shaped, serrated, bead-shaped, wrinkled, terraced, burr-shaped, continuous spiral-shaped, etc.

[0011] Preferably, a plurality of protrusions can be circumferentially arranged; preferably, the ends of the protrusions face upward, that is, towards the top end direction of the auxiliary component, so as to wipe the anal sinus and the nearby mucosa to the greatest extent.

[0012] Of course, the above-shaped protrusions can also be two types of protrusions with upward-facing ends and downward-facing ends, arranged in an up-and-down staggered and / or other staggered manner.

[0013] Furthermore, there are pits above the upward protruding body at the free end and pits below the downward protruding body at the free end. When the device moves upward, downward and / or rotates in the human rectum, the pits above the upward protruding body at the free end and / or below the downward protruding body at the free end can accommodate feces, inflammatory secretions, foreign bodies, etc. that are scraped off by the protruding body and remain in the anal sinus and rectal mucosa, more effectively removing feces, inflammatory secretions, foreign bodies, etc.

[0014] In order to ensure that feces, inflammatory secretions, and foreign bodies accommodated in the pits due to wiping operations do not shift when the device moves up and down and / or rotates, secondary pits and / or multiple protrusions are provided in the pits to better retain the scraped feces and the like.

[0015] Furthermore, a protrusion conforming to the anal sinus is provided on the outer surface of the auxiliary component, and the pit is provided on the protrusion conforming to the anal sinus; the protrusion conforming to the anal sinus means that it can penetrate and fully fill the inside of the hollow anal sinus, and it is easier to scrape off the feces, inflammatory secretions, foreign bodies, etc. remaining in the anal sinus and timely accommodate them in the pit and remove them from the body.

[0016] In order to make full use of the drugs in the drug storage component, the drug channel is arranged between the outer surface of the rod-shaped component and the inner surface of the auxiliary component. The top of the auxiliary component covers the top of the rod-shaped component, and the drug outlet of the drug channel is arranged on the auxiliary component.

[0017] In order to transport fluid substances that can be used for lubrication, cleaning, and treatment, a drug storage component for storing drugs is further included. The drug outlet of the drug storage component is connected to the drug inlet of the drug channel; the drug storage component can store liquid water or drug solutions, and even pastes and gels, playing roles such as lubrication, antibacterial, cleaning, and promoting wound healing.

[0018] In order to facilitate the insertion of the device into the rectum and limit the length of insertion into the rectum, a radially extending part is provided in the bottom region of the rod-shaped component and / or the bottom region of the auxiliary component, which abuts against the anus during use, and the device above the radially extending part can enter the rectum.

[0019] In order to display the length of the device inserted into the rectum, scale lines with sequentially increasing values from the top of the auxiliary component to the bottom of the auxiliary component are provided on the outer surface of the device.

[0020] The beneficial effects of the present invention are:

[0021] 1. The auxiliary component of the present invention is provided with a recess for accommodating drugs and / or fecal matter, and a protrusion that can penetrate into the anal sinus and stimulate the rectal mucosa. During use, feces, inflammatory secretions, foreign objects, etc. can be wiped and removed thoroughly, and it can further stimulate the anal canal and rectal mucosa, stimulate the sense of fullness and the fullness reflex of the rectum, and stimulate the nerve endings in the anal cushion area such as the Pacinian corpuscle for the sense of tension, the genital corpuscle for the sense of friction, and the Golgi-Mazzoni corpuscle for the sense of pressure, promoting defecation; it helps to eliminate constipation caused by anal sinus inflammation, helps to prevent and treat anal sinusitis after diarrhea, helps in the prevention, care and treatment of anorectal diseases such as hemorrhoids and anal fissures, helps diarrhea patients to clean the residual feces, inflammatory secretions, foreign objects, etc. in the anal sinus and rectal mucosa in time, and avoids blocking the anal gland opening and causing inflammation.

[0022] 2. The drug channel of the present invention is arranged between the outer surface of the rod-shaped component and the inner surface of the auxiliary component and / or on the auxiliary component. The diameter of the drug channel is smaller than that of the drug delivery channels such as existing glycerin suppositories, and the drug residue is less. The drugs in the drug storage component can fully act on the anal sinus and rectal mucosa of the human body; moreover, the drug outlet of the drug channel is closer to the anal canal and rectal mucosa. When the drug is extruded, it has a certain flushing speed, which can more effectively flush the anal canal and rectal mucosa, and is more likely to remove the feces, inflammatory secretions, foreign objects, etc. remaining in the anal sinus and rectal mucosa; when squeezing the drug through the drug channel, the relatively weak area on the auxiliary component expands due to the impact pressure and produces a wavy change. The local swelling can further stimulate the anal canal and rectal mucosa, stimulate the sense of fullness and the fullness reflex of the rectum, and promote defecation.

[0023] 3. It can be used for the daily cleaning and maintenance of the anal canal and can train the sensitivity of physiological functions such as the "sampling reflex" and "defecation reflex" of the anal canal. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The drawings related to the present invention are as follows:

[0025] Figure 1A : Anatomical schematic diagram of the anal canal and anal sinus;

[0026] Figure 1B : Cross-sectional view of the anal sinus;

[0027] Figure 1C : Schematic diagram of the action of traditional products on the anal sinus;

[0028] Figure 1D : Schematic diagram of Embodiment 1 of the present invention;

[0029] Figure 1E : Schematic diagram of the action of Embodiment 1 of the present invention on the anal sinus;

[0030] Figure 1F : Schematic diagram of Embodiment 1 of the present invention entering the rectum;

[0031] Figure 2 : Schematic diagram of Embodiment 2 of the present invention;

[0032] Figure 3 : Schematic diagram of Embodiment 3 of the present invention;

[0033] Figure 4A : Schematic diagram of Embodiment 4 of the present invention with secondary lacunae;

[0034] Figure 4B : Schematic diagram of Embodiment 4 of the present invention with protrusions;

[0035] Figure 5 : Schematic diagram of Embodiment 5 of the present invention;

[0036] Figure 6 : Schematic diagram of Embodiment 6 of the present invention; Detailed implementation manners

[0037] The embodiments of the present invention are not limited as follows:

[0038] Embodiment 1:

[0039] First, the position, brief structure of the human anal sinus and the current situation of using traditional glycerin suppositories are described. As Figure 1A , 1B , and as shown in 1C, the opening A5 of the anal gland A4 is blocked by feces or foreign matter B; the drug F conveyed by the traditional glycerin suppository rod-shaped body entering the anal canal A1 from the anus A0 cannot remove the feces or foreign matter B in the anal sinus A3 located at the dentate line A2.

[0040] As Figures 1D-1FAs shown in the series of attached drawings, Embodiment 1 of the present invention includes: a rod-shaped member 1, an auxiliary member 2, and a drug passage 3 for delivering drugs. The drug passage 3 is provided with at least one drug inlet 31 and at least one drug outlet 32. The auxiliary member 2 is conformally fitted on the rod-shaped member 1. The hardness of the material of at least the part of the auxiliary member 2 that enters the rectum is lower than that of the rod-shaped member 1. The auxiliary member 2 is provided with pits 20 that can accommodate drugs and / or fecal matter, including linear, drop-shaped, scattered, serrated, beaded, ring-shaped, wrinkled, terraced, bag-shaped, and continuous spiral-shaped, with the opening direction the same as or intersecting the longitudinal axis direction of the rod-shaped member 1. At least one opening 201 is provided on the pits 20. The pits 20 can be simple depressions, or bag-shaped with openings formed by partial covering of the depressions, or bag-shaped formed by partial covering of non-depressed areas of the auxiliary member. The auxiliary member 2 can be integrally made of medical-grade thermoplastic elastomer TPE material or silicone rubber material, which not only has good biocompatibility but also is relatively soft in texture and has higher comfort when contacting the human body. The rod-shaped member and the auxiliary member, each member can be a single part or composed of multiple parts. To facilitate the insertion of the device into the rectal part and limit the insertion length of the device into the rectal part, a radially extending part 24a is provided in the bottom end 14 area of the rod-shaped member and / or the bottom end 24 area of the auxiliary member, which abuts against the anus during use, and the part of the device above the radially extending part 24a can enter the rectum. The outer surface of the device is provided with scale lines S that increase numerically from the top end 23 of the auxiliary member to the bottom end 24 of the auxiliary member to show the length of the device entering the rectum. In addition, as Figure 1D shown, the present device further includes a drug storage member 4 for storing drugs. The drug outlet 41 of the drug storage member 4 is connected to the drug inlet 31 of the drug passage 3. The drug storage member 4 can be embedded and tightly connected to the rod-shaped member 1 or connected by threads. In this embodiment, the drug storage member 4 is fan-shaped and made by blow molding. The drug storage member 4 has a drug storage cavity with a certain volume, and stores rectal lubricants such as glycerin, paraffin oil, and mannitol inside, or can be ointments, emulsions, etc. that have the functions of lubricating the anorectal wall, softening feces, promoting defecation, antibacterial, anesthetic, and supplementing probiotics. During use, insert the present device into the human rectal part through the anus, squeeze the drug storage member 4 to make the drugs inside it enter the drug passage 3 through the drug outlet 41, and then enter the rectum from the drug outlet 32 of the drug passage 3. Perform multiple operations of entering and exiting to apply the drugs to the human anal wall and rectal wall, stimulate and massage the anorectal wall, and play the role of promoting defecation and related drug effects.

[0041] To more effectively stimulate and massage the anorectal wall and clean and remove feces, inflammatory secretions, foreign bodies, etc. remaining inside the anal sinus, the outer surface 21 of the auxiliary member is also provided with protrusions 211 including cord-like, nail-like, boss-like, hook-like, drop-like, cross-striped, scattered, serrated, beaded, wrinkled, terraced, burr-like, and continuous spiral-shaped; as Figures 1D-1FAs shown, in this embodiment, the protrusions 211 and the pits 20 are both hook-shaped. The pits 20 are arranged between two adjacent protrusions 211. The pits 20 are flexible and easy to deform, and can wipe and remove feces, inflammatory secretions, foreign bodies, etc. remaining in the anal sinuses and on the rectal mucosa, and then take them out of the body. This helps to eliminate constipation caused by anal sinus inflammation, helps to prevent and treat anal sinusitis after diarrhea, and helps diarrhea patients clean the feces, inflammatory secretions, foreign bodies, etc. remaining in the anal sinuses and on the rectal mucosa in time, avoiding blockage of the anal gland openings and causing inflammation. The pits 20 can also hold a certain amount of drugs with functions such as lubrication, cleaning, and antibacterial.

[0042] During use, as Figure 1E shown, when the device enters the human anal canal A1, the protrusions 211 on the outer surface 21 of the auxiliary component penetrate into the anal sinuses, closely contact and wipe the anal sinus mucosa, and the feces or foreign bodies B blocking the anal gland openings A5 are wiped off. At this time, continue to move forward, as Figure 1F shown, the feces or foreign bodies scraped off in the anal sinuses enter the interior of the pits 20 and are taken out of the body together with the device, preventing the feces and the like scraped off from a certain anal sinus by the protrusions 211 from being pushed into other anal sinuses. While stimulating the anal canal and rectal mucosa and the sense of fullness and fullness reflex of the rectum, this device can more effectively wipe and remove feces, inflammatory secretions, foreign bodies, etc.

[0043] Embodiment 2:

[0044] Different from the previous embodiment, as Figure 2 shown, pits 20 are provided above the upward protrusions 211a at the free end and pits 20 are provided below the downward protrusions 211b at the free end. When the device moves upward, downward and / or rotates inside the human rectum, the pits provided above the upward protrusions 211a at the free end and / or below the downward protrusions 211b at the free end can hold feces, inflammatory secretions, foreign bodies, etc. remaining in the anal sinuses and on the rectal mucosa. The feces or foreign bodies scraped off in the anal sinuses enter the interior of the pits 20 and are taken out of the body together with the device, more effectively and fully wiping and removing feces, inflammatory secretions, foreign bodies, etc.

[0045] Embodiment 3:

[0046] Different from Embodiment 1, as Figure 3 shown, the pits 20 are formed by partially covering non-depressed areas of the auxiliary component to form a bag shape, which is easy to mold. The pits 20 with the openings 201 facing the top end 23 of the auxiliary component and the pits 20 with the openings 201 facing the bottom end 24 of the auxiliary component are arranged in sequence. The pits 20 can not only hold feces, inflammatory secretions, foreign bodies, etc. wiped and removed when the device moves upward or downward, but also closely contact and stimulate the anal canal and rectal mucosa to promote defecation.

[0047] Example 4:

[0048] Different from Example 1, as Figure 4A , a secondary recess 201 is provided in the recess 20, as Figure 4B , a plurality of columnar protrusions 202 are provided in the recess 20. The soft stools of patients with diarrhea are likely to stay inside the anal sinus or on the rectal mucosa, and the bacteria, viruses, etc. carried by them are likely to cause intestinal infections and inflammation. The secondary recess 201 and / or the protrusions 202 can ensure that the feces, inflammatory secretions, foreign objects, etc. contained in the recess 20 will not shift when the device moves up and down and / or rotates. The feces or foreign objects scraped off in the anal sinus enter the inside of the recess 20 and are taken out of the body together with the device, preventing the feces, etc. scraped off from a certain anal sinus by the protrusion 211 from being pushed into other anal sinuses, and more effectively and stably cleaning them out of the anal canal.

[0049] Example 5:

[0050] Different from Example 1, as Figure 5 , a protrusion 212 conforming to the anal sinus is provided on the outer surface 21 of the auxiliary component. The recess 20 is provided on the protrusion 212 conforming to the anal sinus. The protrusion 212 conforming to the anal sinus means that it can penetrate and fully fill the inside of the hollow anal sinus. The feces or foreign objects scraped off in the anal sinus enter the inside of the recess 20 and are taken out of the body together with the device, making it easier to scrape off the residual feces, inflammatory secretions, foreign objects, etc. in the anal sinus, more effectively cleaning the anal sinus, stimulating the defecation receptor at the bottom of the anal sinus, and promoting defecation.

[0051] Example 6:

[0052] Different from Example 5, as Figure 6 , the drug channel 3 is provided between the outer surface 11 of the rod-shaped component and the inner surface 22 of the auxiliary component, specifically formed by the channel-like gap between the two. The top 23 of the auxiliary component covers the top 13 of the rod-shaped component. The drug outlet 32 of the drug channel 3 is provided on the auxiliary component 2. The diameter of the drug channel is small, and the drug residue is small. The drug in the drug storage component can fully act on the human anal sinus and rectal mucosa; and the drug outlet of the drug channel is closer to the anal canal and rectal mucosa. When the drug is extruded, it has a certain flushing speed, which can more effectively flush the anal canal and rectal mucosa and wash away the feces, inflammatory secretions, foreign objects, etc. remaining in the anal sinus; when squeezing the drug through the drug channel, the relatively weak area on the auxiliary component expands due to the impact pressure to produce a wavy change, and the local swelling can more stimulate the anal canal and rectal mucosa, stimulating the sense of fullness and fullness reflex of the rectum, and promoting defecation.

[0053] When various solutions of the present invention are used, they can repeatedly enter and exit the anus, increasing the wiping frequency to play a more sufficient wiping and cleaning role; for constipated patients, wiping and stimulating the anal sinus A3 can promote gland secretion, play a self-lubricating role, and can stimulate the defecation reflex; for patients with diarrhea, the soft feces remaining in the anal sinus and on the rectal mucosa after defecation are wiped and removed and then contained in the recesses and removed from the body together with the device. Similar to brushing teeth for routine oral cleaning, even if there are no anorectal diseases, wiping and cleaning the anal sinus and rectal mucosa after each bowel movement every day will play a role in preventing anorectal diseases such as anal sinusitis.

Claims

1. A rectal administration device, comprising a rod-shaped member (1) having a top end and a bottom end, an auxiliary member (2), and a drug passage (3) for delivering drugs. The drug passage (3) is provided with at least one drug inlet (31) and at least one drug outlet (32). The auxiliary member (2) conforms to and fits over the rod-shaped member (1), and at least the part of the auxiliary member (2) entering the rectum is made of a material with a hardness lower than that of the rod-shaped member (1). It is characterized in that: The auxiliary member (2) is provided with recesses (20) capable of accommodating drugs and / or fecal matter, and at least one opening is provided on the recesses (20); the drug passage (3) is arranged between the outer surface (11) of the rod-shaped member and the inner surface (22) of the auxiliary member and / or is arranged on the auxiliary member (2); the auxiliary member (2) is further provided with protrusions (211) including cord-like, nail-like, boss-like, hook-like, water-drop-like, cross-striped, scattered dot-like, serrated, bead-like, wrinkled, terraced, burr-like, continuously spiral-like shapes; the recesses (20) are arranged between two adjacent protrusions (211).

2. The rectal administration device according to claim 1, It is characterized in that: The auxiliary member (2) is provided with recesses (20) with opening directions the same as or intersecting with the longitudinal axis direction of the rod-shaped member (1), including line-like, water-drop-like, scattered dot-like, serrated, bead-like, ring-like, wrinkled, terraced, bag-like, continuously spiral-like shapes.

3. The rectal administration device according to claim 2, It is characterized in that: A recess (20) is provided above the upward protruding body at the free end (211a) and / or a recess (20) is provided below the downward protruding body at the free end (211b).

4. The rectal administration device according to claim 1, It is characterized in that: The outer surface of the auxiliary member is further provided with a protrusion (212) conforming to the anal sinus, and the recess (20) is arranged on the protrusion (212) conforming to the anal sinus.

5. The rectal administration device according to claim 1, It is characterized in that: The recess (20) is provided with secondary recesses (201) and / or a plurality of protrusions (202).

6. The rectal administration device according to claim 1, It is characterized in that: It further includes a drug storage member (4) for storing drugs, and the drug outlet (41) of the drug storage member (4) is communicated with the drug inlet (31) of the drug passage (3).

7. The rectal administration device according to claim 1, It is characterized in that: The outer surface of the device is provided with scale lines (S) numerically increasing from the top end (23) of the auxiliary member to the bottom end (24) of the auxiliary member to show the length of the device entering the rectum.

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