A device for collecting hair samples

Abstract

The present invention provides a device for collecting hair samples, including a hair cutting unit and a hair quantitative collection unit. The hair cutting unit is assembled with the hair quantitative collection unit through a piston, a buckle and an elastic element, and the hair sample can be sampled by pressing the shell. The hair sample collection device has a simple structure, is easy to use, safe and reliable, can easily perform quantitative hair sampling, is convenient to hold, and can be used with both hands or even one hand to hold the hair sample collection device for hair sampling, and can obtain hair samples with consistent length, neat arrangement and consistent quantity. The obtained samples can be directly used for extracting analyzed substances or directly testing.

Description

[0001] This application claims the priority of the Chinese prior application, application number: 202010780199X, filing date August 5, 2020, all contents of which are made part of the present invention. Technical Field

[0002] The invention relates to a collecting device, in particular to a device for collecting hair as a sample for detection in the field of rapid diagnosis. Background Art

[0003] The following background technology introduction is merely an introduction to some background common sense and does not constitute any limitation to the present invention.

[0004] Medical or household rapid testing devices are usually used to detect whether a sample contains an analyte, such as for early pregnancy testing, drug testing, etc. The testing device has a collection chamber for collecting the sample to be tested, and a test element is installed in the collection chamber. After the sample to be tested enters the collection chamber through the opening of the collection chamber, it contacts the test element, and the test element tests the sample to be tested. The test element has a detection area for displaying the test result, and the test result can be read from the outside of the collection chamber through the side wall of the collection chamber.

[0005] When the sample is a hair sample, it is difficult to detect. First, the hair contains the sample, but it is necessary to dissolve and extract the analyte from the hair through physical or chemical methods to prepare it into a solution before the next step of analysis can be carried out. The traditional method is to cut the hair with scissors, put it in a sample bag, and then send it to the testing agency. In this way, the testing agency needs to continue processing after receiving the sample, such as continuing to cut or organize it, and then use chemical reagents to dissolve the analyte, which brings a lot of inconvenience to the processing of the sample.

[0006] At present, the substances to be analyzed in hair sample detection (such as drug abuse) are generally colloidal gold, enzyme-linked immunosorbent or liquid or gas chromatography, but all of them need to be treated with chemical reagents to analyze the substances from the hair.

[0007] Therefore, it is necessary to provide a collection device for collecting hair samples to improve the sample processing process so that the sample can be directly used for the extraction of the substance to be analyzed. Summary of the invention

[0008] The purpose of the present invention is to provide a novel hair sample collection device in view of the defects and shortcomings of the prior art. The device has a simple structure, is easy to use, and can easily perform quantitative sampling of hair. The obtained samples can be directly used for the extraction of analyzed substances or for direct testing.

[0009] To achieve the above object, the present invention provides a device for collecting hair samples, which includes a hair cutting unit, a hair quantitative collection unit and a piston structure; the hair cutting unit is assembled with the hair quantitative collection unit through the piston structure.

[0010] The hair quantitative collection unit described in the present invention can be used to collect hair quantitatively. The quantitative means that the collected hair samples remain consistent in length (after being cut by the hair cutting unit), are roughly the same in number, and are neatly arranged, and can be directly used for the subsequent extraction and detection of substances to be analyzed in the hair samples.

[0011] The piston structure enables the hair cutting unit and the hair quantitative collecting unit to be movably connected together.

[0012] Furthermore, a buckle is provided on the hair cutting unit or the hair quantitative collecting unit, and the hair cutting unit and the hair quantitative collecting unit are connected via the buckle and a piston structure, and the hair cutting unit can move along the piston structure.

[0013] The hair cutting unit can move along the piston structure, which means that the hair cutting unit can move along the movement direction of the piston structure to open or close. If the piston structure is placed vertically, the movement is up and down.

[0014] The buckle can also limit the movement of the hair cutting unit to a certain extent. When the hair cutting unit moves upward to the end of the buckle, it cannot continue to move upward due to the limitation of the buckle.

[0015] Furthermore, the buckle is combined with the buckle edge to realize the connection between the hair cutting unit and the hair quantitative collection unit; when the buckle is located on the hair cutting unit, the buckle edge is arranged on the hair quantitative collection unit; when the buckle edge is arranged on the hair cutting unit, the buckle is located on the hair quantitative collection unit; and an elastic element is arranged on the piston structure.

[0016] In some embodiments, the number of the buckles may be one or more, which are respectively disposed on each side of the hair cutting unit or the hair quantitative collection unit.

[0017] Furthermore, the piston structure includes a piston and a piston chamber, which are respectively arranged on the hair cutting unit and the hair quantitative collection unit; when the hair cutting unit is provided with a piston, the hair quantitative collection unit is provided with a piston chamber matching the piston; when the hair quantitative collection unit is provided with a piston, the hair cutting unit is provided with a piston chamber matching the piston.

[0018] Furthermore, the hair cutting unit comprises a housing and a cutting element; the cutting element is fixed in the housing, and the piston is arranged in the housing.

[0019] Furthermore, the cutting element is a blade. Any sharp material that can be used for cutting can be used as a cutting element and is within the protection scope of the present invention.

[0020] Furthermore, the blades include two groups fixed on both sides of the shell.

[0021] Furthermore, the hair quantitative collection unit includes a carrier, a quantitative hole and a collection table, which are connected in sequence. The carrier is connected to the hair cutting unit and can be used to carry the hair cutting unit; the piston chamber is arranged in the carrier.

[0022] In some embodiments, the carrier can be used to carry the hair cutting unit. The carrier can be a platform structure, or a structure that encloses the hair cutting unit on one side, two sides, three sides or four sides; or a structure that is enclosed by the hair cutting unit on one side, two sides, three sides or four sides.

[0023] Furthermore, blade grooves are respectively provided on both sides of the carrier. When the hair cutting unit and the carrier are assembled into one, the two sets of blades are respectively inserted into the blade grooves on both sides of the carrier.

[0024] Furthermore, the quantitative hole is a slotted hole with one side open.

[0025] Furthermore, the quantitative hole is an arc-shaped slot hole with one side open formed by the connecting part of the carrier and the collecting platform, and there are two quantitative holes distributed on the left and right sides.

[0026] The quantitative holes are slots with one side open, located on both sides of the hair quantitative collection unit, and are the connecting parts between the carrier and the collection platform. When hair is inserted into the two quantitative holes at the same time, the number of hair samples is limited by the size restrictions of the quantitative holes at both ends, so that the number of hair samples inserted is basically the same, and the process of inserting hair is very convenient.

[0027] Furthermore, the collecting table is an open trough structure, which is fixedly or detachably connected to the quantitative hole.

[0028] In some embodiments, a partition can be set at the junction of the collection platform and the quantitative hole, that is, the upper edge of the two sides of the collection platform. When hair sampling, after the hair sample is inserted into the quantitative hole, it can be placed on the partition, making the hair sample more stable and the cutting process easier.

[0029] The collection table structure is more convenient for taking and placing hair samples. After being cut by two sets of blades at the same time, the cut hair samples fall into the collection table, so that hair samples with consistent length, neat arrangement and consistent quantity can be obtained.

[0030] Furthermore, the number of the piston or piston chamber is more than one.

[0031] In some embodiments, the number of the pistons or piston chambers is 1, 2, 3, 4, 5, 6, etc.

[0032] Furthermore, the housing is provided with two pistons, and the carrier is provided with two piston cavities corresponding to the two groups of pistons respectively.

[0033] Furthermore, an elastic element is arranged on each piston structure; when the cutting element of the hair cutting unit moves downward along the piston structure, the elastic element is compressed, thereby cutting the hair.

[0034] Furthermore, the elastic element is a spring, which is sleeved on the piston cavity or on the piston; when the spring is sleeved on the piston cavity, the diameter of the spring is greater than the outer diameter of the piston cavity, and the length of the spring is greater than the length of the piston cavity; when the spring is sleeved on the piston, the diameter of the spring is greater than the diameter of the piston, smaller than the outer diameter of the piston cavity, and greater than or smaller than the inner diameter of the piston cavity.

[0035] Furthermore, the piston cavity is embedded in the carrier, the spring is sleeved on the piston, and the diameter of the spring is larger than the inner diameter of the piston cavity. When the piston moves toward the inner wall of the piston cavity, the spring is blocked outside the piston cavity and is compressed.

[0036] In some embodiments, the spring may be fixedly connected to the housing at one end and connected to the carrier at the other end, so that the housing is movably connected to the carrier through the spring.

[0037] In some embodiments, the spring is not fixedly connected, and the movable connection between the housing and the carrier can be achieved only through the connection between the piston and the piston chamber.

[0038] Furthermore, the buckle is located on the shell; and the carrier is provided with a buckle edge for buckling the buckle.

[0039] Any number of buckles can be arranged around the shell, and the end positions of the buckles must remain consistent, so as to ensure that the hair cutting unit remains stable when it moves to the end of the buckles.

[0040] In some embodiments, the shell is provided with four buckles, which are respectively located on the front side and the rear side of the shell, with two buckles each on the front side and the rear side.

[0041] Furthermore, a pressing portion for easy pressing is provided on the outer surface of the shell.

[0042] The device for collecting hair samples provided by the present invention has a hair cutting unit with a first position and a second position. When in the first position, the hair cutting unit is in the initial first position, and the elastic element is in the initial natural state; an external force presses the pressing part of the surface of the hair cutting unit shell, so that the hair cutting unit overcomes the elastic force of the elastic element, and when in the second position, the piston enters the piston cavity, the blade enters the quantitative unit, and the elastic element is compressed, thereby cutting the hair; when the external force is eliminated, the elastic element returns to the non-compressed state, and the hair cutting unit also returns to the initial first position.

[0043] The reciprocating motion of the hair cutting unit is realized by the elastic element being compressed or restoring its elasticity.

[0044] The hair sample collection device provided by the present invention can be prepared into various sizes according to actual needs, and can be designed according to the length of the hair to be sampled, by controlling the distance between the two sets of blades; it can also be designed according to the fact that in the actual sampling process, it may be necessary to hold the hair sample collection device with one hand for sampling, so the device can be prepared into a small and light device that is easy to hold in hand.

[0045] In another aspect, the present invention provides a method for collecting hair samples, the method comprising the following steps:

[0046] 1) placing hair in the hair quantitative collection unit of the device as described above, and pressing the hair cutting unit to cut the hair;

[0047] 2) Removing the hair for subsequent processing and testing, wherein the subsequent processing includes extracting the substance to be analyzed in the hair with chemical reagents

[0048] Furthermore, the hair sample in step 1) needs to be placed in the quantitative hole of the hair quantitative collection unit first.

[0049] The quantitative holes of the hair sample collection device provided by the present invention are two slots with one side open. When in the initial position, the blade is retracted into the blade slot. When sampling, the hair sample is inserted from the openings of the two quantitative holes and kept under the blade. Then, the thumb of one hand gently presses the pressing part of the shell, and the other hand can hold the bottom of the collection table, so as to facilitate the application of force to the shell, and the cut hair sample falls into the collection table, thereby completing the sampling.

[0050] The reason why hair drug testing has a longer traceability period is mainly because the retention mechanism of drugs in hair is significantly different from that in biological samples such as blood and urine. The entry of drugs into urine and blood is a process of continuous metabolism and rapid degradation, and the traces of drugs will completely disappear within a few days. After drugs enter the human body, they will enter the hair follicles with the blood circulation. The drug precursors and their metabolites will be fixed by the keratin in the hair and stably retained in the hair. After the hair that records drug use information grows out of the scalp, the drugs and their metabolites will migrate from the root end to the tip end of the hair as the hair grows. Therefore, the drug use history of the person being tested can be inferred through segmented testing. So, how long can the drug use history be tested? This mainly depends on the length of the hair. As long as the hair is long enough, such as a woman's hair that is several tens of centimeters long, it can even reflect the drug use situation within a few years. According to the two factors of the growth rate of yellow people's hair and the time of drug rehabilitation, a section of hair at the root end can be cut in a targeted manner, which can then reflect the conduct of drug addicts over a period of time. Therefore, in order to obtain more accurate hair location, such as drug detection, the closer to the skin, the earlier the drug use. As the hair grows, if the hair away from the skin contains drugs, it indicates that the drug use occurred at an earlier stage.

[0051] At present, the traditional method is to use scissors (medical scissors) to cut hair samples. However, generally, the hair is cut from 3 mm away from the skin. The samples of different lengths reserved can indicate the length of drug abuse history. For example, by cutting the hair into different lengths such as 3 cm, 6 cm, 7 cm, 8 cm, 10 cm, etc., the length of drug abuse history can be roughly calculated. Using scissors to cut hair samples is difficult to operate and can easily damage the skin. In addition, it is not easy to quantify, but a weighing device is needed to weigh the weight of the sample. In addition, if segmented sampling is required, it is not easy to achieve segmented shearing of different sizes due to the softness of the hair. The hair sample collection device provided by the present invention can solve these problems well, thereby very conveniently achieving quantitative sampling of hair samples.

[0052] The hair sample collection device provided by the present invention has the following beneficial effects:

[0053] 1. Easy to hold, the hair sample collection device can be held with both hands or even one hand for hair sampling;

[0054] 2. Simply press the housing and move it up and down to take the hair sample;

[0055] 3. It is convenient to obtain hair samples quantitatively. The obtained samples can be directly used for the extraction of analyzed substances or for direct testing;

[0056] 4. Simple structure, ingenious design, easy to use and safe. BRIEF DESCRIPTION OF THE DRAWINGS

[0057] Figure 1 This is a schematic diagram of the structure of the hair sample collection device provided in Example 1.

[0058] Figure 2 This is a cross-sectional view of the hair sample collection device provided in Example 1.

[0059] Figure 3 This is an exploded view of the hair sample collection device provided in Example 1.

[0060] Figure 4 This is a schematic structural diagram of the hair cutting unit of the hair sample collection device provided in Example 1.

[0061] Figure 5 This is a schematic structural diagram of the hair quantitative collection unit of the hair sample collection device provided in Example 1.

[0062] Figure 6 This is a schematic diagram of the hair sample collection device provided in Example 1 in a sampling state.

[0063] Detailed description

[0064] The structures or technical terms involved in the present invention are further explained below. If not otherwise specified, they are understood and interpreted according to the general terms commonly used in the art.

[0065] Detection

[0066] Detection means to test or examine a substance or material for its presence or absence. The substance or material may be, for example, but not limited to, a chemical substance, an organic compound, an inorganic compound, a metabolite, a drug or a drug metabolite, an organic tissue or a metabolite of an organic tissue, a nucleic acid, a protein or a polymer. In addition, detection may also mean the amount of the substance or material tested. Assays may also refer to immunoassays, chemical assays, enzyme assays, etc.

[0067] sample

[0068] In the present invention, the sample collected by the detection device includes biological fluid. The initial state of the sample can be liquid, solid or semi-solid. The solid or semi-solid sample can be converted into a liquid sample by any appropriate method, such as mixing, crushing, macerating, incubating, dissolving, enzymolysis, etc., and then poured into the collection chamber, and the sample is detected by the test element to determine whether it contains the analyte. The sample can be taken from the human body, animals, plants, nature, etc. Samples taken from the human body can be, for example, liquid samples such as blood, serum, urine, cerebrospinal fluid, sweat, lymph, saliva, gastric juice, etc.; solid or semi-solid samples such as feces, hair, keratin, tartar, finger / toe nails, etc. Samples taken from plants can be, for example, solid samples such as roots, stems, leaves, etc.; liquid or semi-solid samples such as tissue fluid and cell fluid prepared from roots, stems, and leaves. Samples taken from nature can be, for example, liquid samples such as rainwater, river water, seawater, groundwater, etc.; solid or semi-solid samples such as soil, rocks, ores, and petroleum.

[0069] Here, it refers to a hair sample, and the device is used to collect the hair sample as a sample for testing.

[0070] Test components

[0071] The test element refers to a component that can detect the analyte in the sample to be tested. The detection of the analyte by the test element can be based on any technical principle, such as immunology, chemistry, electricity, optics, molecular science, physics, etc. The test element of the present invention can be one or a combination of two or more test elements. The test element has a detection area for displaying the test result, and after the test is performed, the test area displays the test result.

[0072] A common form of test element is test strips. The test strips can detect the sample to be tested based on the principle of immunoassay or chemical analysis, and can adopt non-competitive or competitive analysis modes. The test strips include a sample addition area, a reagent area, and a test area in sequence. After the sample to be tested is added to the sample addition area, it flows to the reagent area through capillary action, reacts with the reagent in the reagent area, and then continues to flow to the test area through capillary action. The test area generates a signal or does not generate a signal, thereby indicating the presence or absence of the analyte in the sample to be tested. For example, if a T line (Test Line) appears in the test area, it indicates that the analyte is not present in the sample to be tested; if the T line does not appear in the test area, it indicates that the analyte is present in the sample to be tested. Some test strips are also provided with a control area, which is located after the test area, and the sample flowing through the test area continues to flow to the control area, and the control area is used to determine whether the test result of the test area is valid. For example, in some test strips, only when the C line (Control Line) appears in the control area can the test result of the test area be shown to be valid, otherwise it indicates that the test result of the test area is invalid. In the present invention, when the test result of the test element can be read only through the test area, the test area of ​​the test element is the above-mentioned test area; when the test result of the test element needs to be judged in combination with the signals generated by the test area and the control area, the test area of ​​the test element includes the test area and the control area. Of course, in some cases, the test result of the test element needs to be judged in combination with the signals of other areas, so the detection area also includes the other areas. That is to say, in the present invention, the complete test result can be read through the detection area of ​​the test element. Generally, the test element includes at least a detection area, through which it can be obtained whether the analyzed substance exists in the sample. For example, through the appearance of color, the change of color, the general color change can be seen through the naked eye, and can also be scanned and read by a scanning device, or the test result can be read by taking a photo. Or there is fluorescence, or rays appear, etc. The test result of the detection area is read by equipment and instruments.

[0073] The test element is generally composed of porous water-absorbing materials, such as filter paper, glass fiber, polyester film, film, paper, non-woven fabric, etc. Any material that can absorb water is acceptable.

[0074] The test element here is used to test the analyzed substance in the hair sample, such as a drug substance. In some methods, it is used to test the analyzed substance extracted or separated from the hair sample.

[0075] The method for processing hair samples can refer to the methods described in the following patent documents, such as the reagent for ablating hair described in the Chinese invention patent application, publication number CN108844922, the extract described in the Chinese invention patent application, publication number CN109828039A, or the extract of the analyzed substance in the hair described in publication number CN110044670A.

[0076] Hair sample or hair specimen

[0077] The so-called hair refers to the hair of mammals, which can be head hair, beard, or hair from any part of the body, such as chest hair, leg hair, or hair around the reproductive organs. In particular, the present invention generally refers to hair. When performing hair sample testing, it is first necessary to collect the hair, then process the collected hair, and extract or dissolve the molecular substance from the hair sample, and then perform subsequent testing. This test can be any test, such as immunoassay, chemical test, gas chromatography, liquid phase test, genetic test, liquid-gas chromatography combined test. The substance to be analyzed is generally a drug substance.

[0078] Analyte

[0079] Examples of analytes that can be used in the present invention include some small molecules, including drugs (such as drugs of abuse). "Drugs of abuse" (DOA) refer to the use of drugs for non-medical purposes (usually to paralyze nerves). Abuse of these drugs can cause physical and mental damage, dependence, addiction and / or death. Examples of drug abuse include cocaine; amphetamine AMP (for example, Black Beauty, White Amphetamine Pills, Dextroamphetamine, Dextroamphetamine Pills, Beans); methamphetamine MET (crank, methamphetamine, crystal, speed); barbiturates BAR (such as Valium, Roche Pharmaceuticals, Nutley, New Jersey); sedatives (i.e., sleeping aids); lysergic acid diethylamide (LSD); depressants (downers, goofballs, barbs, blue devils, yellow jackets, methaqualone); tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline and doxepin); MDMA; PCP; tetrahydrocannabinol (THC, pot, dope, hash, weed, etc.); opiates (i.e. morphine MOP or opium, cocaine COC; heroin, hydroxydihydrocodeinone); antianxiety drugs and sedatives and hypnotics. Antianxiety drugs are a class of drugs mainly used to relieve anxiety, tension, fear, stabilize mood, and Drugs with hypnotic and sedative effects include benzodiazepines BZO (benzodiazepines), atypical BZs, fused diazepines NB23C, benzodiazepines, ligands of BZ receptors, open-ring BZs, diphenylmethane derivatives, piperazine carboxylates, piperidine carboxylates, quinazolinones, thiazine and thiazole derivatives, other heterocyclics, imidazole-type sedatives / analgesics (such as oxycodone OXY, methadone MTD), propylene glycol derivatives-carbamates, aliphatic compounds, anthracene derivatives, etc. The detection device of the present invention can also be used to detect drugs that are for medical purposes but are prone to overdose, such as tricyclic antidepressants (imipramine or analogs) and acetaminophen, etc. These drugs will be metabolized into small molecules after being absorbed by the human body. These small molecules exist in body fluids such as blood, urine, saliva, sweat, etc., or some body fluids contain the above-mentioned small molecules.

[0080] These drug substances were also found in hair samples.

[0081] Collection device

[0082] The present invention provides a collection device for collecting, collecting or storing hair samples. Hair samples are different from ordinary body fluid samples. In body fluid samples, the substances to be analyzed are generally dissolved or contained in the body fluid samples. Once collected, they can be directly used for testing or detection. However, for hair samples, after collection, the hair samples need to be processed, and it is not easy to achieve the purpose of quantification. Therefore, the present invention provides a device specifically for collecting hair samples, which can automatically collect or collect hair samples, can ensure the consistency and accuracy of the collected samples, and can also achieve the purpose of quantification. DETAILED DESCRIPTION

[0083] The present invention will be further described in detail below in conjunction with the examples. It should be pointed out that the examples described below are intended to facilitate the understanding of the present invention and do not have any limiting effect on the present invention.

[0084] Example 1 Hair sample collection device provided by the present invention

[0085] The hair sample collection device provided in this embodiment is as follows: Figures 1 to 6 As shown, Figure 1 is the overall structure diagram of the hair sample collection device, Figure 2 is a cross-sectional view of a hair sample collection device, Figure 3 This is an exploded view of the hair sample collection device. Figure 4 is a schematic structural diagram of a hair cutting unit of a hair sample collection device, Figure 5 is a schematic structural diagram of a hair quantitative collection unit of a hair sample collection device, Figure 6 It is a schematic diagram of the hair sample collection device in the sampling state.

[0086] The device for collecting hair samples provided in this embodiment comprises a hair cutting unit 1, a hair quantitative collection unit 2 and a piston structure 3. The hair cutting unit 1 is assembled with the hair quantitative collection unit through the piston structure 3. The piston structure 3 enables the hair cutting unit 1 and the hair quantitative collection unit 2 to be movably connected together.

[0087] Preferably, the hair cutting unit 1 or the hair quantitative collection unit 2 is provided with a buckle 5, and the hair cutting unit 1 is connected to the hair quantitative collection unit 2 through the buckle 5 and the piston structure 3, and the hair cutting unit 1 can move along the piston structure 3. The hair cutting unit 1 can move along the piston structure 3, which means that the hair cutting unit 1 can move along the movement direction of the piston structure 3 to open or close. If the piston structure 3 is placed vertically, the movement is up and down movement. The buckle 5 can also limit the movement of the hair cutting unit 1 to a certain extent. When the hair cutting unit 1 moves upward to the end 6 of the buckle 5, it cannot continue to move upward due to the restriction of the buckle 5.

[0088] Preferably, the buckle 5 is combined with the buckle edge 18 to realize the connection between the hair cutting unit 1 and the hair quantitative collection unit 2; when the buckle 5 is located on the hair cutting unit 1, the buckle edge 18 is arranged on the hair quantitative collection unit 2; when the buckle edge 18 is arranged on the hair cutting unit 1, the buckle 5 is located on the hair quantitative collection unit 2; and an elastic element 11 is arranged on the piston structure 3. The number of buckles 5 can be one or more, which are respectively arranged on each side of the hair cutting unit 1 or the hair quantitative collection unit 2.

[0089] Preferably, the piston structure 3 includes a piston 12 and a piston chamber 13, which are respectively arranged on the hair cutting unit 1 and the hair quantitative collection unit 2; when the hair cutting unit 1 is provided with a piston 12, the hair quantitative collection unit 2 is provided with a piston chamber 13 matching the piston 12; when the hair quantitative collection unit 2 is provided with a piston 12, the hair cutting unit 1 is provided with a piston chamber 13 matching the piston 12.

[0090] Preferably, the hair cutting unit 1 comprises a housing 7 and a cutting element 8; the cutting element 8 is fixed in the housing 7, and the piston 12 is disposed in the housing 7. The cutting element 8 is any element having a sharp edge and capable of cutting hair, and all of them fall within the protection scope of the present invention. In this embodiment, the cutting element 8 is a blade 9. The blade 9 includes two groups, which are fixed on both sides of the housing 7.

[0091] Preferably, the hair quantitative collection unit 2 comprises a carrier 4, a quantitative hole 15 and a collection platform 16, which are connected in sequence. The carrier 4 is connected to the hair cutting unit 1 and can be used to carry the hair cutting unit 1; the piston chamber 13 is arranged in the carrier 4. The carrier 4 can be used to carry the hair cutting unit 1. The carrier 4 can be a platform structure, or a structure that contains the hair cutting unit 1 on one side, two sides, three sides or four sides; or a structure that is contained by the hair cutting unit 1 on one side, two sides, three sides or four sides. Blade grooves 10 are respectively arranged on both sides of the carrier 4. When the hair cutting unit 1 and the carrier 4 are assembled into one, the two sets of blades 9 are respectively inserted into the blade grooves 10 on both sides of the carrier 4.

[0092] Preferably, the quantitative hole 15 is a slot with one side open. The quantitative hole 15 is an arc-shaped slot with one side open formed by the connection part of the carrier 4 and the collection platform 16. There are two quantitative holes 15, distributed on the left and right sides. The quantitative holes 15 are located on both sides of the hair quantitative collection unit 2 and are the connection parts of the carrier 4 and the collection platform 16. When hair is inserted into the two quantitative holes 15 at the same time, the size of the quantitative holes 15 at both ends is limited, and the number of hair samples is limited at the same time, so that the number of hair samples inserted is basically the same, and the process of inserting hair is very convenient.

[0093] Preferably, the collecting platform 16 is an open slot structure, which is fixedly or detachably connected to the quantitative hole 15. The structure of the collecting platform 16 is more convenient for taking and placing hair samples. After being cut by two sets of blades 9 at the same time, the cut hair samples just fall into the collecting platform 16, and hair samples with consistent length, neat arrangement and consistent quantity can be obtained. In this embodiment, a partition 19 is provided at the junction of the collecting platform 16 and the quantitative hole 15, that is, at the upper edge of the two sides of the collecting platform 16. When sampling hair, after the hair sample is inserted into the quantitative hole 15, it can just rest on the partitions 19 on both sides, making the hair sample more stable and the cutting process easier.

[0094] Preferably, the number of the pistons 12 or piston chambers 13 is more than one. For example, the number of the pistons 12 or piston chambers 13 is 1, 2, 3, 4, 5, 6, etc. In this embodiment, the housing 7 is provided with two pistons 12, and the carrier 4 is provided with two piston chambers 13 corresponding to the two groups of pistons 12, respectively.

[0095] Preferably, an elastic element 11 is provided on each piston structure 3; when the cutting element 8 of the hair cutting unit 1 moves downward along the piston structure 3, the elastic element 11 is compressed, and the hair can be cut.

[0096] Preferably, the elastic element 11 is a spring 14, which is sleeved on the piston cavity 13 or on the piston 12; when the spring 14 is sleeved on the piston cavity 13, the diameter of the spring 14 is greater than the outer diameter of the piston cavity 13, and the length of the spring 14 is greater than the length of the piston cavity 13; when the spring 14 is sleeved on the piston, the diameter of the spring 14 is greater than the diameter of the piston 12, smaller than the outer diameter of the piston cavity 13, and greater than or smaller than the inner diameter of the piston cavity 13. The elastic element 11 can of course also be made of other elastic materials, and in this embodiment, the spring 14 is preferably used. In this embodiment, the piston cavity 13 is embedded in the carrier 4, the spring 14 is sleeved on the piston 12, and the diameter of the spring 14 is greater than the inner diameter of the piston cavity 13. When the piston 12 moves toward the inner wall of the piston cavity 13, the spring 14 is blocked outside the piston cavity 13 and compressed. The spring 14 can be fixedly connected to the housing 7 at one end and connected to the carrier 4 at the other end, so that the housing 7 is movably connected to the carrier 4 through the spring 14. The spring 14 may not be fixedly connected, and the housing 7 and the carrier 4 may be movably connected only through the connection between the piston 12 and the piston chamber 13 .

[0097] Preferably, the buckle 5 is located on the housing 7; the carrier 4 is provided with a buckle edge 18 for buckling the buckle 5. Any number of buckles 5 can be provided around the housing 7, and the position of the end 6 of the buckle 5 must be kept consistent, so as to ensure that the hair cutting unit remains stable when it moves to the end 6 of the buckle 5. In this embodiment, the housing 7 is provided with four buckles 5, which are respectively located on the front and rear sides of the housing 7, with two buckles on the front and rear sides.

[0098] Preferably, a pressing portion 17 for easy pressing is provided on the outer surface of the housing 7 .

[0099] The device for collecting hair samples provided by the present invention has a hair cutting unit 1 having a first position 20 and a second position 21. When in the first position 20, the hair cutting unit 1 is in the initial first position, and the elastic element 11 is in the initial natural state; an external force presses the pressing portion 17 on the surface of the housing 7 of the hair cutting unit 1, so that the hair cutting unit 1 overcomes the elastic force of the elastic element 11, and when in the second position 21, the piston 12 enters the piston cavity 13, the blade 9 enters the hair quantitative collection unit 2, and the elastic element 11 is compressed, thereby cutting hair; when the external force is eliminated, the elastic element 11 returns to the non-compressed state, and the hair cutting unit 1 also returns to the initial first position.

[0100] The reciprocating motion of the hair cutting unit 1 is achieved by the elastic element 11 being compressed or restoring its elasticity.

[0101] The hair sample collection device provided by the present invention can be prepared into various sizes according to actual needs, and can be designed according to the length of the hair to be sampled, by controlling the distance between the two sets of blades 9 to control the length of the sampled hair; it can also be designed according to the actual sampling process, in which the hair sample collection device may need to be held in one hand for sampling, so the device can be prepared into a small and light device that is easy to hold.

[0102] The method for collecting hair samples using the hair sample collection device provided in this embodiment comprises the following steps:

[0103] 1) Place the hair in the quantitative hole 15. Due to the size limitation of the quantitative hole 15, the number of hairs that can be loaded each time is basically the same. Press the hair cutting unit 1, and the two sets of blades 9 cut the hair at the same time to obtain a hair sample with a length of 8 cm, a consistent number, and neatly arranged;

[0104] 2) Removing the hair for subsequent processing and testing, wherein the subsequent processing includes extracting the substance to be analyzed in the hair with chemical reagents.

[0105] The hair sample collection device provided in this embodiment includes a housing 7, on which blades 9 are arranged, respectively, at both ends of the housing 7, and the housing 7 has a piston 12 and a spring 14, the piston 12 passes through the retractable spring 14, and the housing 7 is also provided with a buckle 5, which can be snapped on the four sides of the carrier 4, for example, on the edge of the buckle edge 18 of the carrier 4. One end of the blade 9 is fixedly connected to the housing 7, and the other end is exposed and can be inserted into the blade grooves 10 at both ends of the carrier 4. The blade grooves 10 can protect the blade 9, making it safer to use. In addition, when the blade 9 moves, it can also accurately pass through the quantitative hole 15 to cut off the hair that crosses the hole.

[0106] The assembled structure of the housing 7 and the carrier 4 is as follows: Figure 1 As shown, in this embodiment, since the buckle 5 is stuck at the edge end 6, the spring 14 is not compressed and has a reverse force, so the connection between the buckle 5 and the carrier 4 is more secure. The piston 12 passes through the piston cavity 13 on the carrier 4, but the diameter of the spring 14 is larger than the diameter of the piston cavity 13, so the spring 14 contacts the surface of the carrier 4, realizing the expansion and contraction of the spring 14.

[0107] The housing 7 has an initial position on the carrier 4, at which time the spring 14 is in a natural state, and the piston 12 is in a first position in the piston chamber 13 of the carrier 4. At this time, the cutting edge of the cutting blade 9 is in the blade gap and is in a safe position. When it is necessary to shear and sample the hair, the pressing part 17 of the housing 7 is pressed hard to overcome the reaction force of the spring 14, so that the housing 7 is close to the surface of the carrier 4, and the spring 14 continues to be compressed to the second compression state. At this time, the piston 12 also moves together, and the blade 9 also moves with the housing 7, and the movement distance can be freely adjusted. The blade 9 moves to the position of the quantitative hole 15 and cuts off the hair sample located in the quantitative hole 15.

[0108] In this embodiment, the quantitative hole 15 is located at the lower end of the carrier 4 and is connected to a collecting platform 16. The hair sample cut from the quantitative hole 15 falls onto the collecting platform 16, and then the sample is taken out from the collecting platform 16. Since the size of the quantitative hole 15 can be determined, the amount of the hair sample can be determined. In addition, since the distance between the two sets of blades is fixed, the length of the cut hair is also fixed, so that the purpose of quantitative sampling can be achieved.

[0109] The quantitative holes 15 of the hair sample collection device provided in this embodiment are two slots with one side open. When in the initial position, the blade 9 is retracted into the blade slot 10. When sampling, the hair sample is inserted from the openings of the two quantitative holes 15 and kept under the blade 9. Then, the thumb of one hand gently presses the pressing part 17 of the housing 7, and the other hand can hold the bottom of the collection table 16, so as to facilitate the application of force to the housing 7, and the cut hair sample falls into the collection table 16, thereby completing the sampling.

[0110] When the hair sample is placed in the quantitative hole 15, the shell 7 is pressed to make the shell 7 overcome the reaction force of the spring 14, so that the shell 7 moves downward from the initial position, and the blades 9 at both ends of the shell 7 also move downward, so that the blades cut the hair in the quantitative hole 15, and the quantitative length and the lateral volume of the quantitative hole 15 limit the lateral volume of the hair. After cutting, release the fingers, the force pressing the shell 7 disappears, and the compressed spring 14 needs to return to the original state or the first compressed state, so that the shell 7 returns to the initial state, and the cut hair sample falls into the collection table 16, completing a certain quantitative sampling of hair. In this way, sampling can be repeated many times.

[0111] Example 2: Detachable collection table

[0112] This embodiment adopts the hair sample collection device provided in Embodiment 1, wherein the collection table 16 in the hair quantitative collection unit 2 is detachably connected to the quantitative hole 15. When the sampling is completed, the collection table 16 is removed from the base to complete the sampling.

[0113] Example 3 Obtaining Hair Samples of Different Sizes

[0114] This embodiment uses the hair sample collection device provided in Embodiment 1, and the distance between the two sets of blades is 12 cm respectively.

[0115] The method for collecting hair samples using the hair sample collection device provided in this embodiment comprises the following steps:

[0116] 1) Place the hair in the quantitative hole 15. Due to the size limitation of the quantitative hole 15, the number of hairs that can be loaded each time is basically the same. Press the hair cutting unit 1, and the two sets of blades 9 cut the hair at the same time to obtain a hair sample with a length of 8 cm, a consistent number, and neatly arranged;

[0117] 2) Removing the hair for subsequent processing and testing, wherein the subsequent processing includes extracting the substance to be analyzed in the hair with chemical reagents, such as for drug analysis.

[0118] The above description is only a specific implementation mode of the invention, but the protection scope of the invention is not limited thereto, and any changes or substitutions that are not conceived through creative work should be included in the protection scope of the invention.

[0119] Although the present invention is disclosed as above, the present invention is not limited thereto. Any person skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the scope defined by the claims.

Claims

1. A device for collecting hair samples with one hand, characterized in that: The invention comprises a hair cutting unit, a hair quantitative collection unit and a piston structure; the hair cutting unit is assembled with the hair quantitative collection unit through the piston structure; a buckle is arranged on the hair cutting unit or the hair quantitative collection unit, the hair cutting unit and the hair quantitative collection unit are connected through the buckle and the piston structure, and the hair cutting unit can move along the piston structure; the hair cutting unit comprises a shell and a cutting element; the cutting element is a blade; the blade comprises two groups, which are fixed on both sides of the shell; the hair quantitative collection unit comprises a carrier, a quantitative hole and a collection platform, the carrier, the quantitative hole and the collection platform are connected in sequence, the carrier is connected with the hair cutting unit, and can be used to carry the hair cutting unit; the quantitative hole is an arc-shaped slot hole with one side open formed by the connecting part of the carrier and the collection platform; An elastic element is arranged on the piston structure; When the cutting element of the hair cutting unit moves downward along the piston structure, the elastic element is compressed and the hair can be cut.

2. The device according to claim 1, characterized in that The buckle is combined with the buckle edge to realize the connection between the hair cutting unit and the hair quantitative collection unit; when the buckle is located on the hair cutting unit, the buckle edge is arranged on the hair quantitative collection unit; when the buckle edge is arranged on the hair cutting unit, the buckle is located on the hair quantitative collection unit; an elastic element is arranged on the piston structure.

3. The device according to claim 2, characterized in that The piston structure includes a piston and a piston cavity, which are respectively arranged on the hair cutting unit and the hair quantitative collection unit; when the hair cutting unit is provided with a piston, the hair quantitative collection unit is provided with a piston cavity matching the piston; when the hair quantitative collection unit is provided with a piston cavity, the hair cutting unit is provided with a piston matching the piston cavity.

4. The device according to claim 1, characterized in that The cutting element is fixed in the housing, and the piston is arranged in the housing.

5. The device according to claim 3, characterized in that The piston chamber is arranged in the carrier.

6. The device according to claim 1, characterized in that Blade grooves are respectively arranged on both sides of the carrier. When the hair cutting unit and the carrier are assembled into one, the two groups of blades are respectively inserted into the blade grooves on both sides of the carrier.

7. The device according to claim 1, characterized in that The quantitative hole is a slotted hole with one side open.

8. The device according to claim 7, characterized in that There are two quantitative holes, which are distributed on the left and right sides.

9. The device according to claim 1, characterized in that The collecting platform is an open trough structure, which is fixedly or detachably connected to the quantitative hole.

10. The device according to claim 3, characterized in that The number of the piston or piston chamber is more than one.

11. The device according to claim 10, characterized in that The shell is provided with two pistons, and the carrier is provided with two piston chambers corresponding to the two groups of pistons respectively.

12. The device according to claim 11, characterized in that An elastic element is arranged on each piston structure; when the cutting element of the hair cutting unit moves downward along the piston structure, the elastic element is compressed, so that the hair can be cut.

13. The device according to claim 12, characterized in that The elastic element is a spring, which is sleeved on the piston cavity or on the piston; when the spring is sleeved on the piston cavity, the diameter of the spring is greater than the outer diameter of the piston cavity, and the length of the spring is greater than the length of the piston cavity; when the spring is sleeved on the piston, the diameter of the spring is greater than the diameter of the piston, smaller than the outer diameter of the piston cavity, and greater than or smaller than the inner diameter of the piston cavity.

14. The device according to claim 13, characterized in that The piston cavity is embedded in the carrier, the spring is sleeved on the piston, and the diameter of the spring is larger than the inner diameter of the piston cavity.

15. The device according to claim 1, characterized in that The buckle is located on the shell; and a buckle edge for buckling the buckle is provided on the carrier.

16. The device according to claim 1, characterized in that The outer surface of the shell is provided with a pressing portion for easy pressing.

17. A method for collecting hair samples, characterized in that: The following steps are involved: 1) placing hair in the hair quantitative collection unit of the device according to any one of claims 1 to 16, and pressing the hair cutting unit to cut the hair; 2) Removing the hair for subsequent processing and testing, wherein the subsequent processing includes extracting the substance to be analyzed in the hair with chemical reagents.

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