A novel micro hook-shaped electrode device

Abstract

The present invention discloses a micro hook-shaped electrode device, specifically relating to the technical field of medical devices. It includes a plurality of micro hook-shaped electrode assemblies, a flexible sheet-shaped base, a fixing layer, a flexible electrode layer, and an electroencephalogram (EEG) signal receiver; the micro hook-shaped electrode assembly includes a micro hook and a metal wire connected to the micro hook, and the metal wire sequentially passes through the fixing layer and the flexible sheet-shaped base; a connecting piece is provided on the metal wire outside the flexible sheet-shaped base; the bottom of the flexible electrode layer is provided with elastic fixing grooves having the same number as the connecting pieces; a conducting piece is provided in the elastic fixing grooves; a signal receiving and processing unit and a wireless signal transmitter are integrated in the flexible electrode layer, and the signal receiving and processing unit is electrically connected to the wireless signal transmitter; the wireless signal transmitter is electrically connected to the EEG signal receiver. The technical solution of the present invention solves the problem that the existing EEG acquisition device is not convenient for acquiring the EEG signals of rats or mice, and can facilitate the acquisition of the EEG signals of rats or mice.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a novel micro hook-shaped electrode device. Background Art

[0002] Electroencephalogram is a graph that records the spontaneous and rhythmic electrical activities of brain cell groups through electrodes, providing a diagnostic basis for analyzing diseases. Repeatedly collecting electroencephalograms from the same animal not only reduces the use of experimental animals but also effectively avoids the problem of individual differences among different animals within a group. Currently, in clinical experiments, mice are usually used for experiments, and a mouse experimental device is used to record the sleep electroencephalogram, anesthetized electroencephalogram, and the cranial field potential of mice. During the experiments of recording the sleep electroencephalogram, anesthetized electroencephalogram, and the cranial field potential of mice, a brain electrode is usually directly connected to a biological signal recording system, or a recording electrode, a signal receiver, and a transmitter are fixed to the skull together to achieve the recording of the sleep electroencephalogram, anesthetized electroencephalogram, and the cranial field potential of mice.

[0003] Currently, the existing electrodes for collecting animal electroencephalogram signals have the following deficiencies or defects in animal electroencephalogram collection:

[0004] First of all, the existing electrodes for collecting animal electroencephalogram signals are large in volume and heavy in weight. For larger animals such as rats and guinea pigs, the electrode body causes inconvenience in the movement of experimental animals and a decrease in comfort. For smaller experimental animals such as mice, the electrode body even affects their main activities such as eating and drinking and brings greater pressure to their heads. Since the heads of rats or mice are small and their structures are similar to cones, it is inconvenient and time-consuming for the detection personnel to install the electrode device for collecting electroencephalogram signals.

[0005] In addition, due to the large volume and heavy weight of the electrodes for collecting animal electroencephalogram signals, when installed on the skulls of rats or mice, because rats or mice like to move, their related components are likely to fall off, interfering with the collection of electroencephalogram signals. Moreover, rats or mice are sensitive animals. When they feel uncomfortable in their heads, they will constantly scratch the electroencephalogram collection device with their claws and teeth. During the process of being scratched by claws and teeth, the electroencephalogram collection device has a large interference effect, which is not conducive to the collection of electroencephalogram signals. Summary of the Invention

[0006] The present invention aims to provide a novel micro hook-shaped electrode device, which solves the problem that the existing electroencephalogram collection device is not convenient for collecting electroencephalogram signals of rats or mice.

[0007] To achieve the above object, the technical solution of the present invention is as follows: A novel micro hook-shaped electrode device includes a plurality of micro hook-shaped electrode components, a flexible sheet-shaped base, a fixing layer, a flexible electric plate layer, and an electroencephalogram signal receiver. The fixing layer, the flexible sheet-shaped base, and the flexible electric plate layer are fixedly connected in sequence from bottom to top;

[0008] The micro hook-shaped electrode assembly includes a micro hook and a metal wire connected to the micro hook. The end of the metal wire away from the micro hook sequentially passes through a fixing layer and a flexible sheet base; a connecting member is provided on the metal wire outside the flexible sheet base;

[0009] At the bottom of the flexible electrode layer, there are elastic fixing grooves with the same number as the connecting members. Each elastic fixing groove is snap-connected to the corresponding connecting member; a conducting member for contacting the connecting member is provided in the elastic fixing groove, and the conducting member is located within the flexible electrode layer;

[0010] A signal receiving processor and a wireless signal transmitter that are commonly electrically connected to all the conducting members are integrated within the flexible electrode layer. The signal receiving processor is electrically connected to the wireless signal transmitter; the wireless signal transmitter is electrically connected to an electroencephalogram signal receiver.

[0011] Principle and effect of the technical solution:

[0012] During the experiments of sleep electroencephalogram recording, anesthetic electroencephalogram recording, and cranial field potential recording of mice, through the mouse experimental device, the micro hook-shaped electrode in this solution is fixed to the brain region of the mouse. The micro hook-shaped electrode assembly composed of the micro hook and the metal wire is used to collect the electroencephalogram signal of the mouse, and the collected electroencephalogram signal is transmitted to the signal receiving processor within the flexible electrode layer through the connecting member and the conducting member. The signal receiving processor processes the collected electroencephalogram signal of the mouse and wirelessly transmits it to the electroencephalogram signal receiver through the wireless signal transmitter. The experimenter can electrically connect the terminal device and the PC to the electroencephalogram signal receiver, and transmit the electroencephalogram signal of the mouse received by the electroencephalogram signal receiver to the terminal device or the PC, thereby realizing the collection of the electroencephalogram signal of the mouse and forming an electroencephalogram of the mouse on the terminal device or the PC, and realizing the sleep electroencephalogram recording, anesthetic electroencephalogram recording, and cranial field potential recording of the mouse.

[0013] Further, the micro hook is composed of a stainless steel spring and a molded nylon with a gold-plated beryllium copper hook, and the stainless steel spring is arranged on the gold-plated beryllium copper hook.

[0014] With the above settings, the micro hook is composed of a molded nylon with a stainless steel spring and a gold-plated beryllium copper hook, which is convenient for the collection of the electroencephalogram signal of the mouse brain and the transmission of the collected electroencephalogram signal.

[0015] Further, the fixing layer is a strong adhesive layer connected to the bottom of the flexible sheet base.

[0016] With the above settings, by using the strong adhesive layer as the fixing layer, it is convenient to achieve the effect of stably fixing the micro hook-shaped electrode assembly, the flexible sheet base, and the flexible electrode layer to the head of the mouse.

[0017] Further, the flexible sheet base is made of a soft polymer material.

[0018] With the above arrangement, the flexible sheet base made of a soft polymer material facilitates the stable fitting of the device to the mouse's head after being fixed thereto.

[0019] Further, the flexible electrode layer uses a polyimide substrate.

[0020] With the above arrangement, the flexible electrode layer using a polyimide substrate makes the device lightweight and facilitates reducing the pressure of the device on the mouse's head.

[0021] Further, the connecting member uses a graphene conductive ball; the conducting member uses a graphene conductive sheet.

[0022] With the above arrangement, the connecting member using a graphene conductive ball and the conducting member using a graphene conductive sheet facilitate ensuring the rapid and stable transmission of the electroencephalogram signals of the mouse collected by the micro hook-shaped electrode assembly to the signal receiving and processing unit.

[0023] Compared with the prior art, the beneficial effects of this solution are as follows:

[0024] 1. This solution forms a collection end for collecting the electroencephalogram signals of the mouse through the micro hook-shaped electrode assembly, the flexible sheet base, the fixing layer, and the flexible electrode layer. The micro hook-shaped electrode assembly, the flexible sheet base, and the flexible electrode layer are stably fixed to the mouse's head through the fixing layer, facilitating the stable collection of electroencephalogram signals during the process of collecting the electroencephalogram signals of the mouse, and preventing the relevant components from falling off and being less affected by the mouse itself.

[0025] 2. This solution forms an integrated electroencephalogram signal collection end through the micro hook-shaped electrode assembly, the flexible sheet base, the fixing layer, and the flexible electrode layer, and transmits the collected electroencephalogram signals to the electroencephalogram signal receiver in a wireless communication manner, avoiding the influence of the signal transmission connecting wire in the prior art on the electroencephalogram signal collection operation and the electroencephalogram signal collection quality.

[0026] 3. The integrated electroencephalogram signal collection end formed by the micro hook-shaped electrode assembly, the flexible sheet base, the fixing layer, and the flexible electrode layer in this solution has a relatively light weight, brings less pressure to the mouse's head, and is convenient for the installation operation of the experimenter, saving time and effort in the installation operation. Description of the Drawings

[0027] Figure 1 is a schematic structural diagram of a novel micro hook-shaped electrode device of the present invention;

[0028] Figure 2 is a schematic structural diagram after removing the flexible electrode layer in this embodiment;

[0029] Figure 3 is a schematic diagram of the internal structure of the flexible battery layer in this embodiment;

[0030] Figure 4 is a schematic diagram of the structure of the micro-hook-shaped electrode assembly in this embodiment;

[0031] Figure 5 is a schematic diagram of the state installed on the head of a mouse in this embodiment. Detailed implementation manners

[0032] The present invention will be further described in detail below through specific implementation manners:

[0033] The reference numerals in the accompanying drawings of the specification include: 1, micro-hook-shaped electrode assembly; 2, flexible sheet base; 3, fixing layer; 4, flexible battery layer; 5, electroencephalogram signal receiver; 6, micro-hook; 7, metal wire; 8, connecting piece; 9, elastic fixing groove; 10, conduction piece; 11, signal receiving and processing unit; 12, wireless signal transmitter; 13, stainless steel spring; 14, gold-plated beryllium copper hook.

[0034] Embodiment

[0035] As shown in the Figures 1 to 5 accompanying drawings: A novel micro-hook-shaped electrode device includes a plurality of micro-hook-shaped electrode assemblies 1, a flexible sheet base 2, a fixing layer 3, a flexible battery layer 4, and an electroencephalogram signal receiver 5. The fixing layer 3, the flexible sheet base 2, and the flexible battery layer 4 are stacked and fixedly bonded in sequence from bottom to top.

[0036] In this embodiment, the number of the micro-hook-shaped electrode assemblies 1 is three. Each micro-hook-shaped electrode assembly 1 includes a micro-hook 6 and a metal wire 7 connected to the micro-hook 6. The metal wire 7 is wrapped around the edge of the micro-hook 6. The upper end of the metal wire 7 sequentially penetrates through the fixing layer 3 and the flexible sheet base 2 and extends out of the top surface of the flexible sheet base 2. A connecting piece 8 is fixedly welded to the end of the metal wire 7 extending out of the flexible sheet base 2.

[0037] Three elastic fixing grooves 9 for clamping and fixing with the connecting piece 8 are formed at the bottom of the flexible battery layer 4. A conduction piece 10 for contacting with the connecting piece 8 is fixedly installed in the elastic fixing groove 9, and the conduction piece 10 is located inside the flexible battery layer 4.

[0038] A signal receiving and processing unit 11 and a wireless signal transmitter 12 connected to the conduction piece 10 are integrated in the flexible battery layer 4. The signal receiving and processing unit 11 is electrically connected to the wireless signal transmitter 12. The wireless signal transmitter 12 is electrically connected to the electroencephalogram signal receiver 5.

[0039] In this embodiment, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4 are all in sheet form. There are 3 groups of micro-hook electrode assemblies 1, and the elastic fixing grooves 9 are also 3 groups corresponding to the 3 groups of micro-hook electrode assemblies 1. During the experiments on mouse sleep EEG recording, anesthetic EEG recording, and mouse cranial field potential recording, through the mouse experimental device, the micro-hook electrode device in this solution is fixed on the brain region of the mouse. The micro-hook electrode assembly 1 composed of the micro-hook 6 and the metal wire 7 is used to collect the EEG signals of the mouse, and the collected EEG signals are transmitted to the signal receiving and processing unit 11 in the flexible electrode layer 4 through the connector 8 and the conducting member 10. The signal receiving and processing unit 11 processes the collected EEG signals of the mouse and wirelessly transmits them to the EEG signal receiver 5 through the wireless signal transmitter 12. The experimenter can connect the terminal device and the PC to the EEG signal receiver 5, and transmit the EEG signals of the mouse received by the EEG signal receiver 5 to the terminal device or the PC, so as to realize the collection of the EEG signals of the mouse and form an EEG of the mouse on the terminal device or the PC, and realize the sleep EEG recording, anesthetic EEG recording, and mouse cranial field potential recording of the mouse.

[0040] In this solution, through the micro-hook electrode assembly 1, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4, a collection end for collecting the EEG signals of the mouse is formed. The micro-hook electrode assembly 1, the flexible sheet base 2, and the flexible electrode layer 4 are stably fixed on the mouse head through the fixing layer 3, which is convenient for the relevant components not to fall off easily and not to be interfered by the mouse itself during the process of collecting the EEG signals of the mouse, and is conducive to the stable collection of the EEG signals. In addition, the micro-hook electrode assembly 1, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4 form an integrated EEG signal collection end, and the collected EEG signals are transmitted to the EEG signal receiver 5 in a wireless communication manner, avoiding the influence of the signal transmission connection wire in the prior art on the EEG signal collection operation and the EEG signal collection quality. Moreover, the integrated EEG signal collection end formed by the micro-hook electrode assembly 1, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4 has a light weight, brings less pressure to the mouse head, and is convenient for the experimenter to install, and the installation operation saves time and effort.

[0041] The micro-hook 6 is made of molded nylon with a stainless steel spring 13 and a gold-plated beryllium copper hook 14.

[0042] In this embodiment, the micro-hook 6 is made of molded nylon with a stainless steel spring 13 and a gold-plated beryllium copper hook 14, which is convenient for the collection of the EEG signals of the mouse brain and the transmission of the collected EEG signals.

[0043] The fixing layer 3 is a strong adhesive layer connected to the bottom of the flexible sheet base 2.

[0044] In this embodiment, by using a strong adhesive layer as the fixing layer 3, it is convenient to achieve the effect of stably fixing the micro-hook-shaped electrode assembly 1, the flexible sheet base 2, and the flexible electrode layer 4 on the head of a mouse.

[0045] The flexible sheet base 2 is made of a soft polymer material.

[0046] In this embodiment, the flexible sheet base 2 is made of a soft polymer material, which is convenient for the device to fit stably with the mouse's head after being fixed on the mouse's head.

[0047] The flexible electrode layer 4 uses a polyimide substrate.

[0048] In this embodiment, the flexible electrode layer 4 uses a polyimide substrate, making the device lightweight and convenient for reducing the pressure of the device on the mouse's head.

[0049] The connecting piece 8 uses a graphene conductive ball, and the conducting piece 10 uses a graphene conductive sheet.

[0050] In this embodiment, the connecting piece 8 uses a graphene conductive ball, and the conducting piece 10 uses a graphene conductive sheet, which is convenient for ensuring that the electroencephalogram signals of the mouse collected by the micro-hook-shaped electrode assembly 1 are transmitted to the signal receiving and processing unit 11 quickly and stably.

[0051] Through the above embodiments of the present invention, the present invention forms a collection end for collecting the electroencephalogram signals of the mouse through the micro-hook-shaped electrode assembly 1, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4. And through the fixing layer 3, it is convenient to stably fix the micro-hook-shaped electrode assembly 1, the flexible sheet base 2, and the flexible electrode layer 4 on the mouse's head, so that during the process of collecting the electroencephalogram signals of the mouse, the relevant components are not easy to fall off and are not easily interfered by the mouse itself, facilitating the stable collection of the electroencephalogram signals. In addition, in the technical solution of the present invention, the micro-hook-shaped electrode assembly 1, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4 form an integrated electroencephalogram signal collection end, and the collected electroencephalogram signals are transmitted to the electroencephalogram signal receiver 5 in a wireless communication manner, avoiding the influence of the signal transmission connection wire in the prior art on the electroencephalogram signal collection operation and the electroencephalogram signal collection quality. At the same time, in the device of the present invention, the micro-hook-shaped electrode assembly 1, the flexible sheet base 2, the fixing layer 3, and the flexible electrode layer 4 form an integrated electroencephalogram signal collection end, which is lightweight, brings less pressure to the mouse's head, and is convenient for the installation operation of the experimenter, saving time and effort in the installation operation.

[0052] Working principle: During the experiments of sleep EEG recording, anesthetic EEG recording, and mouse cranial field potential recording on mice, through the mouse experimental device, the micro-hook electrode device in this solution is fixed to the brain area of the mouse. The micro-hook electrode assembly 1 composed of the micro-hook 6 and the metal wire 7 collects the EEG signals of the mouse, and transmits the collected EEG signals to the signal receiving and processing unit 11 in the flexible electrode layer 4 through the connector 8 and the conductor 10. The signal receiving and processing unit 11 processes the collected EEG signals of the mouse and wirelessly transmits them to the EEG signal receiver 5 through the wireless signal transmitter 12. The experimenter can connect the terminal device and the PC to the EEG signal receiver 5, and transmit the EEG signals of the mouse received by the EEG signal receiver 5 to the terminal device or the PC, so as to realize the collection of the EEG signals of the mouse and form an EEG of the mouse on the terminal device or the PC, and realize the sleep EEG recording, anesthetic EEG recording, and mouse cranial field potential recording of the mouse.

[0053] The above are only embodiments of the present invention. Specific structures and / or common knowledge such as characteristics well known in the art are not described in detail herein. It should be noted that for those skilled in the art, without departing from the structure of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the implementation effect of the present invention and the practicality of the patent. The protection scope required by this application should be based on the content of its claims, and the specific implementation manners described in the specification can be used to interpret the content of the claims.

Claims

1. A micro hook-shaped electrode device, characterized in that: It includes a plurality of micro-hook electrode assemblies (1), a flexible sheet base (2), a fixing layer (3), a flexible electrode layer (4), and an electroencephalogram signal receiver (5). The fixing layer (3), the flexible sheet base (2), and the flexible electrode layer (4) are fixedly connected in sequence from bottom to top; The micro-hook electrode assembly (1) includes a micro-hook (6) and a metal wire (7) connected to the micro-hook (6). The end of the metal wire (7) away from the micro-hook (6) sequentially passes through the fixing layer (3) and the flexible sheet base (2); A connecting member (8) is provided on the metal wire (7) outside the flexible sheet base (2); Elastic fixing grooves (9) with the same number as the connecting members (8) are provided at the bottom of the flexible electrode layer (4). Each elastic fixing groove (9) is snap-connected to the corresponding connecting member (8); A conductive member (10) for contacting the connecting member (8) is provided in the elastic fixing groove (9), and the conductive member (10) is located inside the flexible electrode layer (4); A signal receiving and processing unit (11) and a wireless signal transmitter (12) that are commonly electrically connected to all the conductive members (10) are integrated in the flexible electrode layer (4). The signal receiving and processing unit (11) is electrically connected to the wireless signal transmitter (12); The wireless signal transmitter (12) is electrically connected to the electroencephalogram signal receiver (5); The fixing layer (3) is a strong adhesive layer connected to the bottom of the flexible sheet base (2); The flexible sheet base (2) is made of a soft polymer material.

2. The micro hook-shaped electrode device according to claim 1, characterized in that: The micro-hook (6) is composed of a molded nylon of a stainless steel spring (13) and a gold-plated beryllium copper hook (14), and the stainless steel spring (13) is arranged on the gold-plated beryllium copper hook (14).

3. The micro hook-shaped electrode device according to claim 1, characterized in that: The flexible electrode layer (4) uses a polyimide substrate.

4. The micro hook-shaped electrode device according to claim 1, characterized in that: The connecting member (8) uses a graphene conductive ball; The conductive member (10) uses a graphene conductive sheet.

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