Liquid pre-embedded device

By designing the combination of chip, sealing film, PDMS film and piston push rod, the problems of complex structure and poor flexibility of existing liquid embedding devices are solved, and effective storage and flexible release of liquid are achieved.

CN114162458BActive Publication Date: 2025-08-08HICOMP MICROTECH (SUZHOU) CO LTD
View PDF 3 Cites 0 Cited by

Patent Information

Application Number
CN202111484002.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-12-07
Publication Date
2025-08-08
Estimated Expiration
2041-12-07

AI Technical Summary

Technical Problem

The existing liquid embedding device has a complex structure and poor flexibility when using preparatory liquids, so it is impossible to effectively store liquids and control flow.

Method used

A liquid embedding device including a chip, a sealing membrane, a PDMS membrane, a sealing assembly and a piston push rod is designed. By overlapping the axis of the through hole and the runner hole on the sealing membrane, combined with the operation of the piston push rod and the PDMS membrane, the accurate control and flexible release of liquid are achieved.

Benefits of technology

It realizes a simple structure of liquid storage and flexible liquid flow control, improves the flexibility of preparatory liquid use, and avoids the problems of liquid waste and uncontrolled flow.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN114162458B_ABST
    Figure CN114162458B_ABST
Patent Text Reader

Abstract

The present invention discloses a liquid pre-embedding device. The liquid pre-embedding device includes: a chip, a sealing film, a PDMS film, a sealing assembly and a piston push rod. The sealing film is pasted and fixed on the chip, and the PDMS film is pasted and fixed on the sealing film; a liquid storage chamber is provided inside the chip, and the sealing assembly is slidably connected to the liquid storage chamber; the piston push rod is slidably connected to the sealing assembly; a flow channel hole is provided on the chip, so that the flow channel hole and the liquid storage chamber are directly connected. The PDMS film is pasted and fixed at the through hole on the sealing film. A liquid outlet is provided on the side of the chip, and the liquid outlet is connected to the flow channel hole through a flow channel. The sealing assembly stores liquid, pushes the piston push rod inside the sealing assembly, and causes the liquid to be injected into the liquid storage chamber, and then flows to the liquid outlet through the flow channel to complete the release of the liquid; a pressure rod or other tool is used to squeeze the PDMS film, thereby blocking the flow channel hole and interrupting the flow of liquid. The liquid pre-embedding device has a simple structure, and while being able to store liquid, it improves the flexibility of operating the prepared liquid flow.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to the field of liquid pre-embedding, and in particular to a liquid pre-embedding device. Background Art

[0002] In chemical and biochemical reaction tests, most of the required reaction reagents are transported from outside, so the reagents need to be sealed to facilitate storage and transportation. Furthermore, after the reagents transported to the test site are unpacked and used, there will often be unused liquid. At the same time, some tests may have a certain time interval, and the liquid after unpacking may react with the outside world or evaporate partially, thereby affecting the test results. Existing liquid storage equipment cannot effectively preserve liquids, and cannot control the flow of liquids after unpacking and use. For the few devices that can control the liquid flow process and can effectively preserve liquids, the structure is too complicated and the manufacturing cost is too high.

[0003] Therefore, the prior art liquid pre-embedded device has the technical problems of complex structure and poor flexibility when using the prepared liquid. Summary of the Invention

[0004] In view of this, the main purpose of the present invention is to provide a liquid pre-embedded device with a simple structure, which is used to effectively store liquid and accurately control the flow of liquid when using the liquid, thereby improving the flexibility of using the prepared liquid.

[0005] In order to achieve the above object, the technical solution of the present invention is achieved as follows:

[0006] The liquid pre-embedding device includes: a chip, a sealing film, a PDMS film, a sealing assembly and a piston push rod. The sealing film is adhered and fixed to the chip, and the PDMS film is adhered and fixed to the sealing film. A liquid storage cavity is provided inside the chip, and the sealing assembly is slidably connected to the liquid storage cavity; the piston push rod is slidably connected to the sealing assembly; a flow channel hole is opened on the chip, and the flow channel hole is directly connected to the liquid storage cavity.

[0007] The sealing film is provided with a through hole, and the axes of the through hole and the flow channel hole coincide with each other.

[0008] The PDMS film is adhered and fixed to the through-holes on the sealing film.

[0009] In one embodiment, a liquid outlet is opened on the side surface of the chip, and the liquid outlet is connected to the flow channel hole through a flow channel.

[0010] In one embodiment, the sealing assembly includes: a sealing cylinder, a silicone sealing ring and a sealing aluminum foil, wherein the silicone sealing ring is fixedly connected to the bottom of the sealing cylinder, and the sealing aluminum foil is adhered and fixed to the port below the sealing cylinder.

[0011] In one embodiment, a circular groove is provided below the sealing cylinder, and the silicone sealing ring is fixedly connected to the inside of the circular groove.

[0012] In one embodiment, the sealing assembly further includes: a limiting ring, which is fixedly connected above the sealing cylinder.

[0013] In one embodiment, a protruding structure is provided at the bottom of the liquid storage cavity, and the protruding structure is integrally formed and connected to the liquid storage cavity.

[0014] In one embodiment, the port of the flow channel hole is a funnel-shaped structure.

[0015] A liquid pre-embedded device of the present invention has the following beneficial effects:

[0016] The liquid pre-embedding device includes: a chip, a sealing film, a PDMS film, a sealing assembly, and a piston push rod. The sealing film is adhered and fixed to the chip, and the PDMS film is adhered and fixed to the sealing film. A liquid storage chamber is provided within the chip, and the sealing assembly is slidably connected to the liquid storage chamber. The piston push rod is slidably connected to the sealing assembly. A flow channel hole is provided on the chip, directly connecting the flow channel hole to the liquid storage chamber. A through hole is provided on the sealing film, and the axes of the through hole and the flow channel hole coincide with each other. The PDMS film is adhered and fixed to the through hole in the sealing film. A liquid outlet is provided on the side of the chip, and the liquid outlet is connected to the flow channel hole through a flow channel.

[0017] The sealing assembly stores liquid. When the liquid needs to be released, the piston push rod inside the sealing assembly is pushed, causing the liquid to be injected into the liquid storage chamber, and then flow through the flow channel to the liquid outlet, completing the liquid release. When the release of liquid needs to be suspended, a tool such as a pressure rod is used to squeeze the PDMS membrane, thereby blocking the flow channel hole and interrupting the liquid flow. This liquid pre-embedded device has a simple structure and can store liquid while increasing the flexibility of using the prepared liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0019] Figure 1 This is an exploded view of a liquid pre-embedded device disclosed in the present invention;

[0020] Figure 2 This is a rear view of a liquid pre-embedded device disclosed in the present invention;

[0021] Figure 3This is a cross-sectional view taken along line AA of a liquid pre-embedded device disclosed in the present invention.

[0022] Figure 4 This is a right side view of a liquid pre-embedded device disclosed in the present invention;

[0023] Figure 5 This is a BB line cross-sectional view of a liquid pre-embedded device disclosed in the present invention.

[0024]

Main component symbol description

[0025] 1. Chip; 2. Sealing film; 3. PDMS film; 4. Sealing assembly; 41. Sealing cylinder; 42. Silicone sealing ring; 43. Sealing aluminum foil; 5. Piston push rod; 6. Limiting ring; 7. Protruding structure. Specific embodiments

[0026] The liquid pre-embedded device of the present invention will be further described in detail below with reference to the accompanying drawings and embodiments of the present invention.

[0027] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0028] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components and / or combinations thereof.

[0029] The terms "comprise," "comprises," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, product, or apparatus.

[0030] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used herein to describe the spatial positional relationship of a device or feature to other devices or features as shown in the figures. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figures. For example, if the device in the drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0031] like Figure 1-Figure 5 As shown, the liquid pre-embedding device includes: a chip 1, a sealing film 2, a PDMS film 3, a sealing assembly 4 and a piston push rod 5. The sealing film 2 is glued and fixed on the chip 1, and the PDMS film 3 is glued and fixed on the sealing film 2; a liquid storage chamber 11 is provided inside the chip 1, and the sealing assembly 4 is slidably connected to the liquid storage chamber 11; the piston push rod 5 is slidably connected to the sealing assembly 4. In order to allow the liquid inside the liquid storage chamber 11 to flow inside the chip 1, a flow channel hole is provided on the chip 1, so that the flow channel hole is directly connected to the liquid storage chamber 11. A through hole is provided on the sealing film 2, and the axes of the through hole and the flow channel hole coincide with each other. The PDMS film 3 is glued and fixed to the through hole on the sealing film 2. In order to allow the PDMS film 3 to block the flow channel hole, a through hole is provided on the sealing film 2, so that the axes of the through hole and the flow channel hole coincide with each other; further, the PDMS film 3 is glued and fixed to the through hole on the sealing film 2.

[0032] The sealing component 4 stores liquid. When the liquid needs to be released, the PDMS membrane 3 is in its original position. At this time, the flow channel hole on the chip 1 is not blocked. The piston push rod 5 inside the sealing component 4 is pushed to inject the liquid contained in the sealing component 4 into the liquid storage chamber 11, and then flow through the flow channel hole and the flow channel to the liquid outlet, completing the release of the liquid. When the release of the liquid needs to be suspended, a tool such as a pressure rod is used to squeeze the PDMS membrane 3, and then block the flow channel hole. At this time, the liquid cannot flow from the flow channel hole to the liquid outlet on the chip. The liquid is blocked inside the chip 1, and the flow of the liquid is interrupted. The liquid pre-embedded device has a simple structure. When the sealing component 4 is not opened, the sealing component 4 is used to store liquid. When the liquid is released, the liquid storage chamber 11 can be used to store liquid. At the same time, by controlling the movement of the piston push rod 5 in the sealing component 4 and the way the PDMS membrane 3 blocks the flow channel hole, the flexibility of the operation of the liquid flow is improved.

[0033] To facilitate the injection of liquid from chip 1 into the device to be filled, a liquid outlet is provided on the side of chip 1, connected to the flow channel via a flow channel. Liquid in chip 1 enters the flow channel through liquid reservoir 11 and the flow channel, and flows through the flow channel to the liquid outlet, completing the liquid release process. The location of the flow channel outlet can be changed to facilitate liquid discharge.

[0034] To facilitate liquid storage, the sealing assembly 4 includes a sealing cylinder 41, a silicone sealing ring 42, and a sealing aluminum foil 43. The silicone sealing ring 42 is fixedly connected to the bottom of the sealing cylinder 41. The silicone sealing ring 42 on the sealing cylinder 41 can form a sealed environment with the liquid storage cavity 11 inside the chip 1, preventing the liquid from overflowing from the liquid storage cavity 11 when released. The sealing aluminum foil 43 is glued and fixed to the port below the sealing cylinder 41, so that the sealing aluminum foil 43 and the sealing cylinder 41 form a sealed space to achieve liquid storage.

[0035] To prevent the silicone seal ring 42 from falling off, a circular groove is provided below the sealing cylinder 41, securing the silicone seal ring 42 within the groove. When the sealing cylinder 41 enters the liquid storage chamber 11, the silicone seal ring 42 and the inner wall of the liquid storage chamber 11 squeeze and rub against each other. The circular groove effectively restricts the movement of the silicone seal ring 42, preventing it from falling off the sealing cylinder 41. Furthermore, the silicone seal ring 42 forms a sealed space with the liquid storage chamber 11, preventing liquid from overflowing from the liquid storage chamber 11 during release.

[0036] To limit the range of movement of sealing cylinder 41, sealing assembly 4 also includes a stop ring 6, which is fixedly attached to the top of sealing cylinder 41. Stop ring 6 serves as a bearing member. When piston push rod 5 within sealing assembly 4 is pushed, stop ring 6 absorbs some of the pressure, preventing sealing assembly 4 from escaping from the bottom of liquid storage chamber 11. Furthermore, stop ring 6 limits the distance sealing assembly 4 can enter liquid storage chamber 11, achieving the technical effect of conveniently controlling liquid release.

[0037] In order to facilitate the control of liquid release, a protruding structure 7 is provided at the bottom of the liquid storage chamber 11 so that the protruding structure 7 is integrally formed and connected with the liquid storage chamber 11, which facilitates the processing and manufacturing of the liquid storage chamber 11 and the protruding structure 7.

[0038] In order to facilitate the PDMS membrane 3 to block the flow channel hole, the port of the flow channel hole is made into a funnel-shaped structure. When the PDMS membrane 3 is squeezed, it is convenient for the PDMS membrane 3 to enter the flow channel hole and cling to the inner wall of the flow channel hole port, completing the process of interrupting the liquid flow.

[0039] The above description is merely a preferred embodiment of the present invention and is not intended to limit the scope of protection of the present invention.

Claims

1. A liquid pre-embedded device, characterized in that: include: A chip (1), a sealing film (2), a PDMS film (3), a sealing assembly (4) and a piston push rod (5), wherein the sealing film (2) is adhered and fixed to the chip (1), and the PDMS film (3) is adhered and fixed to the sealing film (2); A liquid storage cavity (11) is provided inside the chip (1), and the sealing component (4) is slidably connected to the liquid storage cavity (11); the piston push rod (5) is inside the sealing component (4) and is slidably connected to the sealing component (4); The chip (1) is provided with a flow channel hole, and the flow channel hole is directly connected to the liquid storage cavity (11); The sealing film (2) is provided with a through hole, and the axes of the through hole and the flow channel hole coincide with each other; the PDMS film (3) is adhered and fixed to the through hole on the sealing film (2); The port of the flow channel hole is a funnel-shaped structure. When the PDMS membrane (3) is squeezed, the PDMS membrane (3) enters the flow channel hole and clings to the inner wall of the flow channel hole. The sealing assembly (4) comprises: a sealing cylinder (41), a silicone sealing ring (42) and a sealing aluminum foil (43); the silicone sealing ring (42) is fixedly connected to the bottom of the sealing cylinder (41); the sealing aluminum foil (43) is glued and fixed to the port below the sealing cylinder (41); the sealing aluminum foil (43) and the sealing cylinder (41) form a sealed space for storing liquid; when the piston push rod (5) is pushed, the liquid is injected from the sealed space into the liquid storage chamber (11).

2. A liquid pre-embedded device according to claim 1, characterized in that: A liquid outlet is provided on the side of the chip (1), and the liquid outlet is connected to the flow channel hole through a flow channel.

3. A liquid pre-embedded device according to claim 1, characterized in that: A circular groove is provided below the sealing cylinder (41), and the silicone sealing ring (42) is fixedly connected to the inside of the circular groove.

4. A liquid pre-embedded device according to claim 1, characterized in that: The sealing assembly (4) further comprises a limiting ring (6), wherein the limiting ring (6) is fixedly connected above the sealing cylinder (41).

5. The liquid pre-embedded device according to claim 1, characterized in that: A protruding structure (7) is provided at the bottom of the liquid storage cavity (11), and the protruding structure (7) is integrally formed and connected to the liquid storage cavity (11).

Citation Information

Patent Citations

  • Paint brush capable of storing liquid

    CN108577160A

  • Microfluidic valve and microfluid control method thereof

    CN108953758A

  • Cleaning and sterilizing device in postpartum of gynaecology and obstetrics

    CN205163894U