Test kit, assembly base
By providing a micropore tablet, kit, assembly base, and sample detection device, the existing POCT blood cell analyzer has solved the problems of simple functions, complex structure, low automation and high cost, and a disposable product with novel structure and low cost, which has improved detection efficiency and accuracy.
Patent Information
- Application Number
- CN202110152469.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-02-03
- Publication Date
- 2025-03-07
- Estimated Expiration
- 2041-02-03
AI Technical Summary
The existing POCT blood cell analyzers have too simple functions, complex structure, low automation and high cost, making it difficult to meet clinical needs.
It provides a microporous tablet, a kit, an assembly base, and a sample detection device, including a plastic assembly cylinder, a rear cell electrode and a microporous tablet. It has a novel structure and low cost, and is suitable as a disposable consumable product.
It realizes the simplification of the structure and reduces the cost, is suitable for one-time use, avoids repeated cleaning and use of expensive materials, and improves the efficiency and accuracy of detection.
Smart Images

Figure CN114858860B_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of medical devices, and in particular to a microporous sheet, a reagent kit, an assembly seat, and a sample detection device. Background Art
[0002] The blood cell analyzer, also known as blood cell analyzer, blood cell meter, blood cell counter, etc., is one of the most widely used instruments in clinical testing in hospitals.
[0003] A large part of the components in traditional blood cell analyzers belong to the cleaning system, because before the next blood sample test, it is necessary to ensure that the traces of the previous blood sample are cleaned. The entire cleaning system is not only complex in structure and has many components, but also requires a large amount of reagents during the cleaning process, which takes a long time.
[0004] Compared with traditional blood cell analyzers, POCT blood cell analyzers have made great simplifications in instrument components. POCT blood cell analyzers can completely remove the cleaning fluid path related components in traditional blood analysis, greatly reducing the complexity and production cost of the product.
[0005] However, some existing POCT blood cell analyzers have overly simple functions, some have relatively complex structures, some have low automation levels, and some are relatively expensive. Summary of the invention
[0006] The present application provides a microporous sheet, a reagent kit, an assembly seat, and a sample detection device to at least partially solve the above technical problems.
[0007] In order to solve the above technical problems, a technical solution adopted in the present application is: to provide an assembly seat, the assembly seat comprising:
[0008] An assembly cylinder, which is a plastic assembly cylinder and is provided with an axial drainage cavity and a radial liquid outlet groove which are communicated with each other, and the radial liquid outlet groove is used to discharge the gas or liquid in the axial drainage cavity;
[0009] The rear cell electrode is connected to the assembly tube and extends toward the axial drainage cavity.
[0010] The beneficial effects of the present application are: different from the prior art, the microporous sheet, test kit, assembly seat, and sample detection device provided by the present application are novel in structure and low in cost, and can be used as disposable consumable products without the need to use expensive materials that can be repeatedly cleaned and used. BRIEF DESCRIPTION OF THE DRAWINGS
[0011] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative work, among which:
[0012] Figure 1 It is a schematic diagram of the three-dimensional structure of a microporous sheet provided in one embodiment of the present application;
[0013] Figure 2 yes Figure 1 Schematic diagram of the cross-sectional structure of the microporous sheet shown in;
[0014] Figure 3 It is a schematic diagram of an exploded structure of a kit provided in an embodiment of the present application from one perspective;
[0015] Figure 4 It is a schematic diagram of the exploded structure of the kit provided in one embodiment of the present application from another perspective;
[0016] Figure 5 It is a schematic cross-sectional structure diagram of a kit provided in one embodiment of the present application from one viewing angle;
[0017] Figure 6 It is a schematic cross-sectional structure diagram of a kit provided in one embodiment of the present application from another perspective. DETAILED DESCRIPTION
[0018] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.
[0019] It should be noted that if the embodiments of the present application involve directional indications (such as up, down, left, right, front, back...), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.
[0020] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present application, the descriptions of "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by this application.
[0021] Please refer to the first embodiment. Figure 1 and Figure 2 The embodiment of the present application provides a microporous sheet 170, which includes a sheet body 171. The sheet body 171 is provided with micropores 172 that allow cells to pass through one by one. The micropores 172 can be made into different specifications according to cells of different particle sizes. The sheet body 171 is a plastic sheet body or a ceramic sheet body. The mechanical strength of the plastic sheet body or the ceramic sheet body is relatively weak. The embodiment of the present application further provides a reinforcement part 173 on the sheet body 171 to ensure the mechanical strength of the microporous sheet 170, and at the same time has the effect of convenient installation. When the microporous sheet 170 is installed, the micropores 172 are not easily contaminated or worn by contact. The material cost of the plastic sheet body or the ceramic sheet body is relatively cheap, and it can be used as a disposable product without the need to use expensive materials that can be repeatedly cleaned and used.
[0022] The sheet body 171 has a first surface 175 and a second surface 176 opposite to each other. The first surface 175 and / or the second surface 176 is provided with a reinforcement portion 173 .
[0023] The reinforcing portion 173 can be arranged close to the edge of the sheet body 171 . The reinforcing portion 173 can be a structure such as a convex ring. The convex ring can be a continuous integral convex ring or a convex ring formed by multiple convex hulls. The outer edge of the convex ring overlaps or does not overlap with the outer edge of the sheet body 171 .
[0024] The convex ring is connected to the first surface 175 and / or the second surface 176 of the sheet body 171 via a vertical surface, an inclined surface or an arc surface, wherein the inclined surface or the arc surface can further reduce sample residue and improve detection accuracy.
[0025] The first surface 175 of the sheet body 171 is provided with a concave drainage portion 174 around the micropore 172 . The concave drainage portion 174 may be spherical or conical.
[0026] Among them, the ratio of the thickness of the convex ring to the thickness of the sheet 171 is 0.2-2. Preferably, the ratio of the width of the convex ring to the radius of the sheet 171 is less than or equal to 1. If the thickness of the convex ring is too small, it cannot play a good role in strengthening the mechanical strength. If the thickness of the convex ring is too large, it will waste materials. If the thickness of the convex ring is too large, the wall thickness of the micropores 172 of the microporous sheet 170 is also difficult to control, resulting in a more complicated manufacturing process. The ratio of the width of the convex ring to the radius of the sheet 171 is 0.2-0.8. Similarly, if the width of the convex ring is too small, it cannot play a good role in strengthening the mechanical strength. If the width of the convex ring is too large, the wall thickness of the micropores 172 of the microporous sheet 170 is also difficult to control, resulting in a more complicated manufacturing process. If the width of the convex ring is too large (for example, close to the radius of the sheet 171), the axial channel of the micropore 172 will become longer, which will further cause the sample particles to be tested to flow back, which will affect the accuracy of the detection when the cells pass through.
[0027] The microporous sheet 170 provided in this embodiment can improve the mechanical strength of the microporous sheet 170 by setting a reinforcing portion 173 to prevent the microporous sheet 170 made of plastic or ceramic material from being easily deformed during assembly. This embodiment also provides a kit including the aforementioned microporous sheet 170. The specific structure of the kit is referred to below.
[0028] Please refer to the second embodiment. Figures 1 to 6 An embodiment of the present application provides a kit, which includes a box body 100, an assembly seat 160, and a microporous sheet 170.
[0029] The box body 100 includes a forecell 120 . The box body 100 is provided with a forecell electrode 121 corresponding to the forecell 120 . The forecell 120 can be provided with two groups, which are respectively used for cooperating with WBC (white blood cell) detection and RBC (red blood cell) detection.
[0030] like Figure 6 As shown, the assembly seat 160 is connected to the box body 100 , and the assembly seat 160 is provided with an axial drainage cavity 167 (the axial drainage cavity 167 may also be referred to as a back cell) and a back cell electrode 165 extending toward the axial drainage cavity 167 .
[0031] like Figure 1 , Figure 2 , Figure 6 As shown, the microporous sheet 170 is provided with micropores 172 that allow cells to pass through one by one. The microporous sheet 170 is arranged between the front pool 120 and the axial drainage cavity 167. The front pool 120 and the axial drainage cavity 167 are connected through the micropores 172. The front pool electrode 121 and the rear pool electrode 165 are respectively spaced apart on both sides of the microporous sheet 170.
[0032] The assembly seat 160 is detachably connected to the box body 100 .
[0033] In a specific embodiment, the front cell electrode 121 can be integrally injection molded or detachably connected with the box body 100. The rear cell electrode 165 can be integrally injection molded or detachably connected with the assembly seat 160, the front cell electrode 121 and / or the rear cell electrode 165 are columnar electrodes, and the length of the rear cell electrode 165 is greater than or equal to the length of the front cell electrode 121. The microporous sheet 170 can be integrally injection molded or detachably connected with the box body 100, or the microporous sheet 170 can be integrally injection molded or detachably connected with the assembly seat 160.
[0034] The box body 100 is provided with a mounting cavity 130 , and the assembly seat 160 is snap-fitted, threaded, interference-fitted, laser-welded or adhesively-fitted with the mounting cavity 130 .
[0035] The box body 100 and / or the assembly seat 160 are made of plastic. The front cell electrode 121 is embedded in the box body 100 and is flush with, protrudes or recessed in the outer surface of the box body 100. The rear cell electrode 165 is embedded in the assembly seat 160 and is flush with, protrudes or recessed in the outer end surface of the assembly seat 160. The outer ends of the front cell electrode 121 and the rear cell electrode 165 (i.e., the two ends away from each other) are used to connect the working voltage, and the inner ends of the front cell electrode 121 and the rear cell electrode 165 (i.e., the two ends close to each other) are in contact with the sample liquid to be tested. The axial drainage cavity 167 will be filled with the sample liquid to be tested during detection.
[0036] The kit also includes an inner sealing ring 164, which is arranged between the microporous sheet 170 and the front pool 120, specifically between the first surface 175 of the microporous sheet 170 and the front pool 120, so that the sample liquid to be tested in the front pool 120 can only enter the axial drainage cavity 167 through the micropores 172.
[0037] The reagent kit further includes an outer sealing ring 166 , which is disposed between the assembly seat 160 and the free end of the mounting cavity 130 .
[0038] In one embodiment, the inner sealing ring 164 , the outer sealing ring 166 , the microporous sheet 170 and the assembly seat 160 are separate structural components.
[0039] In another embodiment, the inner sealing ring 164, the outer sealing ring 166, the microporous sheet 170 and the assembly seat 160 can be an integrated structural component to reduce the number of assembly parts, reduce assembly difficulty, and save assembly time. Among them, the inner sealing ring 164 and the outer sealing ring 166 can be injection molded using a secondary injection molding process and a relatively soft plastic material.
[0040] In another embodiment, the inner seal ring 164, the outer seal ring 166 and the assembly seat 160 are an integrated structure, and the microporous sheet 170 is detachably connected to the integrated structure, which can reduce the number of assembly parts and ensure the manufacturing accuracy and yield rate of the microporous sheet 170. Among them, the inner seal ring 164 has a certain flexibility. When the microporous sheet 170 is installed with the integrated structure, it can be installed to the rear of the inner seal ring 164 through the flexibility of the inner seal ring 164, and the inner seal ring 164 still seals the first surface 175 of the microporous sheet 170.
[0041] The kit provided in this embodiment has a novel structure and is easy to assemble.
[0042] Please refer to the third embodiment. Figures 1 to 6 The embodiment of the present application provides an assembly seat 160 , which includes an assembly tube 168 and a back cell electrode 165 .
[0043] The assembly cylinder 168 is provided with an axial drainage cavity 167 and a radial liquid outlet groove 1611 (see Figure 4 ), the radial liquid outlet groove 1611 is used to discharge the gas or liquid in the axial drainage cavity 167; the rear cell electrode 165 is connected to the assembly tube 168 and extends to the axial drainage cavity 167.
[0044] The inner end of the radial liquid outlet groove 1611 and the inner end of the assembly tube 168 are the first preset distance, and the inner end of the rear cell electrode 165 and the inner end of the assembly tube 168 are the second preset distance, and the first preset distance is less than or equal to the second preset distance. When the first preset distance is less than the second preset distance, the bubbles in the axial drainage cavity 167 are more easily discharged from the axial drainage cavity 167. If bubbles remain in the axial drainage cavity 167, the detection accuracy will be affected. Wherein, the inner end is based on the interior of the box body 100 as a reference, and when the front cell 120 is used as a reference, the end pointing to the front cell is the inner end, and the end away from the front cell 120 is the outer end. For example, the inner end of the installation cavity 130 is connected to the front cell 120 through the through hole 132, and the outer end of the installation cavity 130 is an open end for receiving the assembly seat 160 for loading.
[0045] The axial length of the radial liquid outlet groove 1611 in the axial drainage cavity 167 is greater than or equal to the length of the rear cell electrode 165 extending into the axial drainage cavity 167. The inner end of the rear cell electrode 165 may or may not extend into the axial drainage cavity 167, that is, the inner end of the rear cell electrode 165 may protrude, be flush with, or be recessed in the cavity bottom surface of the axial drainage cavity 167.
[0046] Furthermore, the outer surface of the assembly cylinder 168 is provided with a recessed area connected to the radial liquid outlet groove 1611 to form a guide groove 1612. The guide groove 1612 can allow the gas or liquid in the axial drainage chamber 167 to flow out through the radial liquid outlet groove 1611 directly above and then flow out through the guide groove 1612 obliquely above. Thus, the two assembly seats 160 can share a pressure pool 140 connected to the two assembly seats 160. The pressure pool 140 passes through the through hole 133 (which can be Figure 5 The fan-shaped structure shown in FIG. 1 is connected to the installation cavity 130 and is further connected to the axial drainage cavity 167 through the guide groove 1612 and the radial liquid outlet groove 1611 in sequence.
[0047] The inner end of the assembly tube 168 is provided with a microporous sheet 170 that allows cells to pass through one by one. The specific structure of the microporous sheet 170 can refer to the above-mentioned embodiment.
[0048] The distance from the inner end of the rear cell electrode 165 to the microporous sheet 170 is a third preset distance, which is 0.2-2 times the axial length of the axial drainage cavity 167. Experimental verification shows that within this range, better signal accuracy can be obtained when performing impedance detection.
[0049] A sink 1613 is provided at the inner end of the assembly tube 168 , the microporous sheet 170 is cooperatively connected to the sink 1613 , and the reinforcement portion 173 of the microporous sheet 170 abuts against the sink 1613 .
[0050] like Figure 4 As shown, the assembly cylinder 168 includes a rear pool cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected. The rear pool cylinder 161 is provided with an axial drainage chamber 167 and a radial liquid outlet groove 1611. The end plate 162 radially connects the rear pool cylinder 161 and the outer cylinder 163. The outer cylinder 163 is spaced apart and sleeved on the outer periphery of the rear pool cylinder 161.
[0051] The radial liquid outlet groove 1611 may be in the shape of a circular hole, a waist-shaped hole or a rectangular hole.
[0052] The present application also provides a test kit, which includes a box body 100 and the aforementioned assembly seat 160, the box body 100 is provided with a front pool 120 and an installation cavity 130 that are connected, the assembly cylinder 168 is connected to the installation cavity 130, and the front pool 120 is connected to the axial drainage cavity 167 through the micropores 172 of the microporous sheet 170.
[0053] The reagent kit and its assembly seat 160 provided in this embodiment can facilitate the discharge of bubbles in the assembly tube 168 by limiting the distance between the inner end of the radial liquid outlet groove 1611 and the inner end of the rear cell electrode 165 and the inner end of the assembly tube 168, thereby preventing bubbles from remaining in the assembly tube 168 and affecting the detection accuracy during impedance detection.
[0054] Please refer to the fourth embodiment Figures 1 to 6 The embodiment of the present application provides an assembly seat 160 , which includes an assembly tube 168 and a rear cell electrode 165 . The rear cell electrode 165 is a columnar electrode, and the rear cell electrode 165 is connected to the assembly tube 168 .
[0055] The assembly cylinder 168 is provided with a radial liquid outlet groove 1611 and a buckling portion 1631, and the buckling portion 1631 is aligned with the radial liquid outlet groove 1611. The buckling portion 1631 can be a buckling hole or a buckling protrusion. Correspondingly, the outer surface of the mounting cavity 130 is provided with a buckle block 131 corresponding to the buckling hole. The opening directions of one buckling portion 1631 and the radial liquid outlet groove 1611 are consistent and aligned, which can facilitate demolding from the same direction during injection molding.
[0056] The assembly tube 168 is provided with an axial drainage cavity 167 , which is communicated with the radial liquid outlet groove 1611 , and the rear cell electrode 165 extends toward the axial drainage cavity 167 .
[0057] The rear cell electrode 165 can be embedded in the assembly seat 160 by injection molding and flush with, protruding from, or recessed from the outer end surface of the assembly seat 160 .
[0058] In the embodiment of the present application, the assembly cylinder 168 includes a rear pool cylinder 161, an end plate 162 and an outer cylinder 163 that are integrally connected. The rear pool cylinder 161 is provided with a radial liquid outlet groove 1611 and an axial drainage cavity 167, and the end plate 162 radially connects the rear pool cylinder 161 and the outer cylinder 163.
[0059] The outer cylinder 163 may extend a plurality of positioning protrusions 1632 spaced apart from each other along the axial direction, and the buckling portion 1631 is disposed corresponding to the positioning protrusions 1632 .
[0060] There is a first preset distance between the inner end of the radial liquid outlet groove 1611 and the inner end of the assembly tube 168, and there is a second preset distance between the inner end of the rear cell electrode 165 and the inner end of the assembly tube 168. The first preset distance is less than or equal to the second preset distance.
[0061] The rear cell electrode 165 and the assembly tube 168 may be integrally formed or detachably connected.
[0062] A sink 1613 is provided at the inner end of the rear cell tube 161 for assembling a microporous sheet 170 that allows cells to pass through one by one.
[0063] The present application also provides a test kit, which includes a box body 100 and the aforementioned assembly seat 160, the box body 100 is provided with a front pool 120 and an installation cavity 130 that are connected, the assembly cylinder 168 of the assembly seat 160 is connected to the installation cavity 130, and the front pool 120 is connected to the axial drainage cavity 167 through the micropores 172 of the microporous sheet 170.
[0064] The reagent kit and its assembly seat 160 provided in this embodiment can facilitate the demolding operation after mold forming by aligning the radial liquid outlet groove 1611 and the buckling portion 1631.
[0065] Please refer to the fifth embodiment Figures 1 to 6 The embodiment of the present application provides an assembly seat 160 , which includes an assembly tube 168 and a rear cell electrode 165 .
[0066] The assembly cylinder 168 is provided with an axial drainage chamber 167 and a radial liquid outlet groove 1611 which are connected to each other. The outer surface of the assembly cylinder 168 is provided with a recessed area connected to the radial liquid outlet groove 1611 to form a guide groove 1612. The guide groove 1612 can make the gas or liquid in the axial drainage chamber 167 flow out through the radial liquid outlet groove 1611 (for example, directly above) and then flow smoothly to the pressure action pool 140 through the guide groove 1612 (for example, obliquely above). Thus, the two assembly seats 160 can share a pressure action pool 140 connected to the two assembly seats 160. The pressure action pool 140 is connected to the pressure action pool 140 through the through hole 133 (which can be Figure 5 The fan-shaped structure shown in FIG. 1 is connected to the installation cavity 130 and is further connected to the axial drainage cavity 167 through the guide groove 1612 and the radial liquid outlet groove 1611 in sequence.
[0067] The rear cell electrode 165 is connected to the assembly tube 168 and extends to the axial drainage cavity 167 .
[0068] The guide groove 1612 is arranged along the outer surface of the assembly tube 168 in the circumferential direction. The guide groove 1612 is an arc-shaped structure with a central angle of 0° to 360°, which can make the sample liquid flow more smoothly to the pressure pool 140. The concave depth of the guide groove 1612 is 1 / 5 to 4 / 5 of the wall thickness of the assembly tube 168, which ensures that the liquid flows out smoothly, and the guide groove 1612 has a certain mechanical strength and is not easy to be damaged.
[0069] The radial liquid outlet groove 1611 is connected to the guide groove 1612 via a transition surface, and the transition surface is a vertical plane, an inclined surface or a curved surface.
[0070] The rear cell electrode 165 is embedded in the assembly seat 160 and is flush with, protruding from, or recessed from the outer end surface of the assembly seat 160 .
[0071] There is a first preset distance between the inner end of the radial liquid outlet groove 1611 and the inner end of the assembly tube 168; there is a second preset distance between the inner end of the rear cell electrode 165 and the inner end of the assembly tube 168; the first preset distance is less than or equal to the second preset distance.
[0072] like Figure 4As shown in the figure, the assembly cylinder 168 includes a rear pool cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected. The rear pool cylinder 161 is provided with a radial liquid outlet groove 1611 and an axial drainage cavity 167. The end plate 162 radially connects the rear pool cylinder 161 and the outer cylinder 163.
[0073] The outer cylinder 163 extends axially to form a plurality of positioning protrusions 1632 that are spaced apart from each other, and the buckling portions 1631 are disposed corresponding to the positioning protrusions 1632 .
[0074] The present application also provides a test kit, which includes a box body 100 and the aforementioned assembly seat 160, the box body 100 is provided with a front pool 120 and an installation cavity 130 that are connected; the assembly cylinder 168 of the assembly seat 160 is connected to the installation cavity 130, and the front pool 120 is connected to the axial drainage cavity 167 through the micropores 172 of the microporous sheet 170.
[0075] The test kit and its assembly seat 160 provided in this embodiment can facilitate two assembly seats 160 to share a pressure action pool 140 connected to the two assembly seats 160, by arranging a radial liquid outlet groove 1611 on the assembly cylinder 168 and forming a recessed area on the outer surface of the radial liquid outlet groove 1611 to form a guide groove 1612, so as to facilitate negative pressure drainage of the pressure action pool 140.
[0076] Please refer to the sixth embodiment. Figures 1 to 6 The embodiment of the present application provides an assembly seat 160 , which includes an assembly tube 168 and a back cell electrode 165 .
[0077] The assembly tube 168 is a plastic assembly tube, which is provided with an axial drainage chamber 167 and a radial liquid outlet groove 1611 which are connected to each other. The radial liquid outlet groove 1611 is used to discharge the gas or liquid in the axial drainage chamber 167; the rear cell electrode 165 is connected to the assembly tube 168 and extends to the axial drainage chamber 167.
[0078] The outer surface of the assembly cylinder 168 is provided with a recessed area connected to the radial liquid outlet groove 1611 to form a guide groove 1612. The guide groove 1612 can make the gas or liquid in the axial drainage chamber 167 flow smoothly to the pressure pool 140 through the guide groove 1612 (for example, diagonally above) after it comes out of the radial liquid outlet groove 1611 (for example, directly above). Thus, the two assembly seats 160 can share a pressure pool 140 connected to the two assembly seats 160. The pressure pool 140 passes through the through hole 133 (which can be Figure 5 The fan-shaped structure shown in FIG. 1 is connected to the installation cavity 130 and is further connected to the axial drainage cavity 167 through the guide groove 1612 and the radial liquid outlet groove 1611 in sequence.
[0079] The assembly cylinder 168 is provided with a buckling portion 1631, which is aligned with the radial liquid outlet groove 1611. The buckling portion 1631 can be a buckling hole. The buckling portion 1631 and the radial liquid outlet groove 1611 are aligned to facilitate demolding from the same direction during injection molding.
[0080] The inner end of the radial liquid outlet groove 1611 and the inner end of the assembly tube 168 are at a first preset distance; the inner end of the rear cell electrode 165 and the inner end of the assembly tube 168 are at a second preset distance; the first preset distance is less than or equal to the second preset distance. When the first preset distance is less than the second preset distance, the bubbles in the axial drainage cavity 167 are more easily discharged from the axial drainage cavity 167. If bubbles remain in the axial drainage cavity 167, the detection accuracy will be affected.
[0081] The axial length of the radial liquid outlet groove 1611 in the axial drainage cavity 167 is greater than or equal to the length of the rear cell electrode 165 extending toward the axial drainage cavity 167 .
[0082] The inner end of the assembly tube 168 is provided with a microporous sheet 170 that allows cells to pass through one by one. The distance from the inner end of the rear cell electrode 165 to the microporous sheet 170 is a third preset distance, and the third preset distance is 0.2-2 times the axial length of the axial drainage cavity 167. The inner end of the assembly tube 168 is provided with a sink 1613, and the microporous sheet 170 is connected to the sink 1613 in a cooperative manner.
[0083] In the embodiment of the present application, the assembly cylinder 168 includes a rear pool cylinder 161, an end plate 162 and an outer cylinder 163 that are integrally connected. The rear pool cylinder 161 is provided with an axial drainage chamber 167 and a radial liquid outlet groove 1611. The end plate 162 radially connects the rear pool cylinder 161 and the outer cylinder 163. The outer cylinder 163 is spaced apart and sleeved on the outer periphery of the rear pool cylinder 161. The buckling portion 1631 is provided on the outer cylinder 163.
[0084] The present application also provides a test kit, which includes a box body 100 and the aforementioned assembly seat 160, the box body 100 is provided with a front pool 120 and an installation cavity 130 that are connected to each other; the assembly cylinder 168 of the assembly seat 160 is connected to the installation cavity 130, the front pool 120 is connected to the axial drainage cavity 167 through the micropores 172 of the microporous sheet 170, the front pool 120, the installation cavity 130, the axial drainage cavity 167, the radial liquid outlet groove 1611, and the pressure action pool 140 together constitute a drainage channel, and the axial drainage cavity 167 can receive negative pressure to suck the sample to be tested in the front pool 120 through the micropores 172 of the microporous sheet 170.
[0085] The reagent kit and its assembly seat 160 provided in this embodiment have novel structures and are easy to manufacture and assemble.
[0086] Please refer to the seventh embodiment. Figures 1 to 6The embodiment of the present application provides a kit, which includes a box body 100 , a hemolytic agent pool 106 disposed on the box body 100 , and a diluent pool 111 disposed near the hemolytic agent pool 106 .
[0087] At least any two of the hemolytic agent pool 106, the diluent pool 111 and the box body 100 are integrally connected, and at least any two of the hemolytic agent pool 106, the diluent pool 111 and the box body 100 are detachably connected. In other words, the box body 100, the hemolytic agent pool 106 and the diluent pool 111 can be a conjoined structure or any separate structure.
[0088] For example, the box body 100, the hemolytic agent pool 106, and the diluent pool 111 are three independent parts and can be detachably connected to each other; or, the diluent pool 111 and the box body 100 are an integral structure, and a separate hemolytic agent container 206 is detachably assembled in the hemolytic agent pool 106; or, the hemolytic agent pool 106 and the box body 100 are an integral structure, and a separate diluent pool test tube is detachably assembled in the diluent pool 111; or, the hemolytic agent pool 106 and the diluent pool 111 are connected as a whole and are detachably connected to the box body 100.
[0089] Any two of the hemolytic agent pool 106, the diluent pool 111, and the box body 100 form a combined unit, and an assembly portion (e.g., the inner peripheral wall of the insertion hole provided on the box body 100) is provided on the combined unit, and a disassembly portion (e.g., the inner peripheral wall of the insertion hole provided on the box body 100) is provided on the other one of the hemolytic agent pool 106, the diluent pool 111, and the box body 100. Figure 3 The outer peripheral wall of the hemolytic agent container 206 shown in the figure), the disassembly portion is cooperatively connected with the assembly portion.
[0090] The surface of the assembly portion or the disassembly portion is further provided with a protruding structure 2061 , and the protruding structure 2061 can make the hemolytic agent container 206 abut and fit tightly with the insertion hole provided on the box body 100 .
[0091] In one embodiment, two assembly positions are provided on the box body 100 , and the hemolytic agent pool 106 and the diluent pool 111 are respectively installed in the two assembly positions.
[0092] In the embodiment of the present application, the box body 100 includes a front pool 120 and a mounting cavity 130 that are connected to each other. The front pool 120 and the mounting cavity 130 are connected through a through hole 132 (see Figure 5 and Figure 6 ) is connected, the front pool 120 is equipped with a front pool electrode 121, the test kit also includes an assembly seat 160 connected to the installation cavity 130, the assembly seat 160 is provided with a microporous sheet 170 and a rear pool electrode 165, the microporous sheet 170 is installed at the through hole 132, the front pool electrode 121 and the rear pool electrode 165 are respectively spaced apart on both sides of the microporous sheet 170, the assembly seat 160 includes an assembly cylinder 168, the assembly cylinder 168 is provided with an axial drainage cavity 167 and a radial liquid outlet groove 1611.
[0093] In the embodiment of the present application, the assembly cylinder 168 includes a rear pool cylinder 161, an end plate 162 and an outer cylinder 163 that are integrally connected. The rear pool cylinder 161 is provided with an axial drainage chamber 167 and a radial liquid outlet groove 1611. The end plate 162 radially connects the rear pool cylinder 161 and the outer cylinder 163. The outer cylinder 163 is spaced apart and sleeved on the outer periphery of the rear pool cylinder 161.
[0094] The usage of the diluent pool 111 is generally relatively large, so in the embodiment of the present application, the volume of the diluent pool 111 is greater than or equal to the volume of the hemolytic agent pool 106 .
[0095] The open ends of the diluent reservoir 111 and the hemolytic agent reservoir 106 are provided with sealing films to facilitate long-term storage of the diluent and hemolytic agent.
[0096] The kit provided in this embodiment has a novel structure and multiple detachable solutions, and can adapt to a variety of different detection needs.
[0097] Please refer to the eighth embodiment. Figures 1 to 6 An embodiment of the present application provides a test kit, which includes a box body 100 and at least one item detection pool, and the at least one item detection pool is integrally connected to the box body 100 or detachably connected.
[0098] The item detection pool includes a first item detection pool for performing a first item detection and a second item detection pool for performing a second item detection. The first item detection pool and / or the second item detection pool are integrally connected to the box body 100 or are detachably connected.
[0099] The test kit also includes a third item detection pool for performing a third item detection, and the third item detection pool is integrally connected to the box body 100 or detachably connected thereto.
[0100] The second project detection pool and the third project detection pool are arranged on the same side of the first project detection pool; or the second project detection pool and the third project detection pool are arranged on both sides of the first project detection pool respectively.
[0101] The detection items of the first item detection pool, the second item detection pool, and the third item detection pool can be selected from specific protein detection, biochemical detection, immunological detection, and routine blood test. For example, the front pool 120, the installation cavity 130, the assembly seat 160, and the pressure pool 140 can be used in conjunction to perform routine blood tests, and the optical detection cup can be used to perform specific protein detection, biochemical detection, immunological detection, etc.
[0102] The detection items of the first item detection pool, the second item detection pool, and the third item detection pool are the same, different, or not completely the same; or any one of the first item detection pool, the second item detection pool, and the third item detection pool supports more than two detection items.
[0103] The box body 100 is provided with an insertion hole, which may include a rectangular insertion hole 107 and a circular insertion hole 108. The second item detection pool is inserted through the insertion hole, or the second item detection pool is provided with a flange to cooperate with the insertion hole.
[0104] The second item detection cell includes a first cell body 207, a second cell body 208, and a connector 2071 connecting the first cell body 207 and the second cell body 208. The connector 2071 connects the first cell body 207 and the second cell body 208 to the box body 100 in the form of an assembly.
[0105] The first item detection pool and / or the second item detection pool are light-transmitting plastic pools or glass pools. The opening ends of the first item detection pool and / or the second item detection pool are provided with sealing films, which can be pierced by the piercing head 204 provided on the box body 100 for use.
[0106] The kit provided in this embodiment has a novel structure and multiple detachable solutions, and can adapt to a variety of different detection needs.
[0107] Please refer to the ninth embodiment. Figures 1 to 6 An embodiment of the present application provides a test kit, which includes a box body 100, and the box body 100 includes a front pool 120, an installation cavity 130 and a pressure pool. The front pool 120 is connected to the installation cavity 130, and the pressure pool 140 is connected to the installation cavity 130. The pressure pool 140 is vertically arranged, and the installation cavity 130 is horizontally arranged.
[0108] The opening end of the installation cavity 130 faces the outer surface of the box body 100 . The test kit also includes an assembly seat 160 , which is connected to the installation cavity 130 . The assembly seat 160 is provided with an axial drainage cavity 167 , which is connected to the pressure pool 140 .
[0109] A drainage gap is formed between the installation cavity 130 and the assembly seat 160 , and the axial drainage cavity 167 is connected to the pressure application pool 140 through the drainage gap.
[0110] The assembly seat 160 is provided with a radial liquid outlet groove 1611, and the axial drainage chamber 167 is connected to the pressure application pool 140 through the radial liquid outlet groove 1611; the assembly seat 160 is provided with a guide groove 1612 adjacent to the radial liquid outlet groove 1611, and the axial drainage chamber 167 is connected to the pressure application pool 140 through the radial liquid outlet groove 1611 and the guide groove 1612.
[0111] The assembly seat 160 is provided with a microporous sheet 170 and a rear cell electrode 165 , and the front cell 120 is provided with a front cell electrode 121 . The front cell electrode 121 and the rear cell electrode 165 are respectively spaced apart and located on both sides of the microporous sheet 170 .
[0112] The assembly seat 160 and the installation cavity 130 are snap-fitted, threaded, interference-fitted, laser-welded, or adhesively-fitted.
[0113] The reagent kit further includes an inner sealing ring 164 and an outer sealing ring 166 . The inner sealing ring 164 is disposed between the microporous sheet 170 and the box body 100 , and the outer sealing ring 166 is disposed between the assembly seat 160 and the box body 100 .
[0114] In the embodiment of the present application, the front pool 120 and the installation cavity 130 are both in two groups, and a pressure pool 140 is connected to the two groups of installation cavities 130 .
[0115] The test kit provided in this embodiment has a novel structure, wherein the front pool 120, the mounting cavity 130, and the pressure pool 140 are interconnected and arranged vertically in sequence. The open end of the pressure pool 140 is located on the upper surface of the box body 100, and the negative pressure source can be applied from above the box body 100, thereby simplifying the structure of the box body 100 and avoiding the side of the box body 100 having more protruding structures.
[0116] Please refer to the tenth embodiment. Figures 1 to 6 An embodiment of the present application provides a reagent kit, which includes a plurality of first pool positions, and the centers of the plurality of first pool positions are arranged roughly in a first straight line or a first arc.
[0117] The test kit also includes a plurality of second pools arranged approximately in a second straight line at the center, and the first straight line and the second straight line are arranged in parallel or vertically spaced relation.
[0118] Alternatively, the reagent kit includes a plurality of second pool positions arranged in a second arc at the center, the first arc and the second arc are arranged in parallel and spaced apart, and the arc can be an arc corresponding to a central angle of 0 to 360.
[0119] The plurality of first cell sites and / or the plurality of second cell sites include impedance detection cells and / or optical detection cells.
[0120] The multiple first pool positions and / or the multiple second pool positions also include a diluent pool 111, which is used to encapsulate the diluent; the multiple first pool positions and / or the multiple second pool positions also include a hemolytic agent pool 106, which is used to encapsulate the hemolytic agent; or the multiple first pool positions and / or the multiple second pool positions also include a sample dilution pool 112, which is used for sample dilution.
[0121] The impedance detection pool is provided with a light-transmitting detection window for cooperating with optical detection, that is, one of the front pools 120 is provided with a light-transmitting detection window for cooperating with optical detection. The front pool 120 can be made of transparent plastic as a whole, and the transmittance and smoothness of the light-transmitting detection window can be the same as those of the front pool 120 or higher than other parts of the front pool 120.
[0122] The plurality of first pool positions and / or the plurality of second pool positions further include a plurality of insertion holes.
[0123] The plurality of first pool positions and / or the plurality of second pool positions include at least one pipette tip accommodating pool (101, 102, 103) and / or a sample accommodating pool 105.
[0124] The plurality of first pool positions and / or the plurality of second pool positions include at least one puncture head accommodating pool 104. The kit provided in the present application is a degradable plastic kit, and by arranging the plurality of pool positions in a straight line, it is convenient for the pipetting device to move a shorter path during automated testing, wherein the pipetting device is used to transfer and mix the liquids in each pool body.
[0125] Please refer to the eleventh embodiment. Figures 1 to 6 The embodiment of the present application provides a test kit, which includes a box body 100, on which are provided a detection area (such as the area formed by the front pool 120, the installation cavity 130, the pressure action pool 140, and the assembly seat 160), a reagent area (such as the area formed by the diluent pool 111, the hemolytic agent pool 106, and the sample holding pool 105), and an accessory placement area (such as the area formed by the pipette tip holding pools 101, 102, 103 and the puncture head holding pool 104).
[0126] The box body 100 also includes an expandable area (such as the area formed by the rectangular insertion hole 107 and the circular insertion hole 108 in the figure), which is arranged close to the detection area, located on one side of the detection area, or located on one side of the reagent area.
[0127] The accessory placement area is arranged close to the reagent area, and the detection area is arranged close to the reagent area.
[0128] The detection area includes an impedance detection cell and / or an optical detection cell, and the optical detection cell is used to detect any one of the parameters of HGB, CRP, and SAA.
[0129] The reagent area includes at least one of a diluent pool, a hemolytic agent pool, and a sample holding pool 105 .
[0130] The reagent area includes a cell body area, and the cell body area is used to detachably mount at least one of a diluent container, a hemolytic agent container 206 and a sample containing cell 105 .
[0131] The accessory placement area includes placement positions for pipette tips 201 , 202 , 203 and / or puncture head 204 .
[0132] The expandable area includes a detachable optical detection cell and / or an impedance detection cell, and the optical detection cell includes a cell for detecting any one of the parameters of HGB, CRP, and SAA.
[0133] The test kit provided in the present application is a degradable plastic test kit, which can facilitate the movement of the pipetting device over a shorter path during automatic detection through a partitioned setting.
[0134] Please refer to the twelfth embodiment. Figures 1 to 6 The embodiment of the present application provides a test kit, which includes a box body 100, on which a detection area (such as an area formed by a front pool 120, a mounting cavity 130, a pressure pool 140, and an assembly seat 160), a reagent area (such as an area formed by a diluent pool 111, a hemolytic agent pool 106, and a sample holding pool 105) and an accessory placement area (such as an area formed by pipette tip holding pools 101, 102, 103 and a puncture head holding pool 104) are arranged, and the reagent area is arranged close to the accessory placement area.
[0135] The box body 100 also includes an expandable area (such as the area formed by the rectangular insertion hole 107 and the circular insertion hole 108 in the figure), which is arranged close to the detection area. Alternatively, the expandable area is arranged close to the side of the detection area or close to the side of the reagent area.
[0136] The reagent area includes a plurality of reagent cells, and the plurality of reagent cells are arranged roughly in a straight line or in an arc.
[0137] The detection area includes an impedance detection cell and / or an optical detection cell, and the optical detection cell is used to detect any one of the parameters of HGB, CRP, and SAA.
[0138] The accessory placement area includes placement positions for pipette tips 201 , 202 , 203 and / or puncture head 204 .
[0139] The expandable area includes a detachable optical detection cell and / or an impedance detection cell, and the optical detection cell includes a cell for detecting any one of the parameters of HGB, CRP, and SAA.
[0140] The reagent area includes at least two cell body areas, and at least two cell body areas include bottomed pools and / or bottomless insertion holes.
[0141] The accessory area includes one or more bottomed pools for mounting pipette tips 201 , 202 , 203 and / or piercing head 204 .
[0142] The expandable area is provided with a circular insertion hole 108 and a rectangular insertion hole 107, which are used to install a detection pool, which is an optical detection pool and / or an impedance detection pool. The test kit provided in this application is a degradable plastic test kit, which can facilitate the movement of the pipette device for a shorter path during automatic detection through a partitioned setting.
[0143] Please refer to the thirteenth embodiment. Figures 1 to 6An embodiment of the present application provides a test kit, which includes a box body 100. The test kit is used for sample detection. The box body 100 is provided with a supporting portion so that the test kit can be stably supported on a receiving surface.
[0144] In one embodiment, the box body 100 includes two support plates (not shown), which serve as support parts. The support plates may be provided with a mark, which may be a barcode, a QR code or an identification chip to record relevant parameters of the test kit.
[0145] The box body 100 is provided with at least one supporting platform or supporting surface near the center of gravity of the reagent box, and the supporting platform or supporting surface serves as a supporting portion.
[0146] In one embodiment, the box body 100 is provided with three supporting protrusions, and the three supporting protrusions form a triangle, and the projection of the center of gravity of the reagent box falls within the area surrounded by the triangle.
[0147] In one embodiment, the box body 100 includes at least one pool body, and the bottom of the pool body can be used as a support portion.
[0148] Optionally, the supporting plate or the supporting platform or the supporting surface or the supporting protrusion and the bottom of the pool body serve together as a supporting portion.
[0149] The pool body includes a receiving chamber and a skirt 124 extending downward from the receiving chamber (see Figure 6 , the structure below the bottom 123 of the front pool 120), the skirt 124 serves as a support portion, and the accommodating cavity can be used to hold reagents, samples, or accessories (201-204).
[0150] The box body 100 provided in the present application is a degradable plastic box body. The test kit is provided with an impedance detection cell and / or an optical detection cell.
[0151] The reagent kit provided in this embodiment is provided with more pools, and a stable support may be formed through the bottom of the pools and / or additionally provided support parts to prevent the reagent kit from tipping over easily.
[0152] Please refer to the fourteenth embodiment. Figures 1 to 6 The embodiment of the present application provides a test kit, which includes a box body 100, and the box body 100 includes a plurality of pool bodies. The pool body includes a accommodating cavity and a support portion connected to the accommodating cavity. The support portion is a solid structure or a hollow structure. The provision of a solid or hollow support portion can increase the relative height of the bottom of the accommodating cavity, which can facilitate the absorption of reagents. The corresponding pipetting device does not need to be inserted too deeply, thereby saving the pre-stored amount of reagents. If it is a solid structure, the center of gravity of the box body 100 can also be moved down, and the overall stability can be more stable; when it is hollow, the plastic material of the box body 100 can be saved.
[0153] The height of the supporting portion is greater than or equal to the wall thickness of the accommodating cavity. The bottom of the accommodating cavity may be a conical bottom, specifically a conical arc bottom, a triangular pyramid bottom or a polygonal pyramid bottom, and the conical bottom extends into the hollow area at the bottom of the supporting portion; or the bottom of the accommodating cavity is a plane bottom, and the accommodating cavity is connected to the supporting portion through the plane bottom.
[0154] When the supporting part is a hollow structure, an open end or a closed end is provided at the bottom of the supporting part.
[0155] The accommodating cavity and the supporting part are integrally formed or detachably connected.
[0156] When the support part is a hollow structure, the cross section of the hollow structure is square, circular, polygonal or irregular, and the height of the support part is 0.1 to 0.8 times the height of the pool body.
[0157] The aforementioned cell body may specifically be any cell body such as a reagent cell, a detection cell, a sample dilution cell 112 or an accessory placement cell (101-104).
[0158] The aforementioned detection cell is used for impedance detection or optical detection.
[0159] An embodiment of the present application also provides a sample detection device, which includes the aforementioned test kit and a detection seat that cooperates with the test kit. The detection seat is used for sample analysis and detection. The detection seat is provided with a power supply component that is electrically connected to the front cell electrode 121 and the rear cell electrode 165. The detection seat may also be provided with optical detection components located on opposite sides of the optical detection cell (for example, the first cell body 207).
[0160] The reagent kit provided in this embodiment can facilitate liquid transfer by a liquid transfer device by setting pool bottoms of different heights. The liquid transfer device does not need to be inserted too deep, thereby saving the pre-stored amount of reagents.
[0161] Please refer to the fifteenth embodiment. Figures 1 to 6 An embodiment of the present application provides a test kit, which includes a box body 100, and the box body 100 is provided with an accessory placement area (101-104), and the accessory placement area is used to place accessories (201-204).
[0162] The lower side of the accessory placement area is provided with a liquid-leakage-proof structure, which can be a bottom pool. The liquid-leakage-proof structure is integrally formed with the box body 100 or is detachably connected. The accessory placement area is provided with a placement hole, and the accessories (201-204) are placed in the placement hole.
[0163] The aperture of the placement hole is smaller than or equal to the maximum radial dimension of the accessory (201-204), so as to prevent the accessory (201-204) from being completely sunk into the placement hole and to prevent the bottom of the accessory (201-204) from contacting and deforming with the bottom of the pool body when the accessory (201-204) is plugged in.
[0164] The box body 100 is provided with a receiving cavity corresponding to the placement hole, and the accessories (201-204) are received in the receiving cavity. The bottom of the receiving cavity is a sealing structure.
[0165] The accommodating cavity and the box body 100 are integrally formed or detachably connected.
[0166] The inner cavity depth of the accommodating cavity is greater than or equal to the length of the accessory (201-204) extending into the accommodating cavity, so as to prevent the accessory (201-204) from protruding too much from the surface of the box body 100 when placed in the accommodating cavity, and at the same time, to prevent the bottom of the accessory (201-204) from contacting and deforming with the bottom of the pool body when the accessory (201-204) is plugged in.
[0167] The length of the attachment (201-204) extending into the accommodating cavity is 0.4 to 1 times the length of the attachment.
[0168] The embodiment of the present application also provides a sample detection device, which includes the aforementioned test kit and a detection seat that cooperates with the test kit, and the detection seat is used for sample analysis and detection.
[0169] When the accessories of the reagent kit provided in this embodiment are removed, the accessories can be received by the bottom pool to prevent the residual liquid carried on the surface of the accessories from leaking.
[0170] Please refer to the sixteenth embodiment. Figures 1 to 6 An embodiment of the present application provides a detection cup assembly, which includes a first cell body 207 and a second cell body 208 connected to the first cell body 207 .
[0171] The first cell body 207 is connected to the second cell body 208 via a connecting piece 2071 , and the connecting piece 2071 is integrally formed with at least one of the first cell body 207 and the second cell body 208 or is detachably connected thereto.
[0172] The connecting member 2071 is provided with at least one cup holder 2072 , and the cup holder 2072 is detachably connected to the first cell body 207 or the second cell body 208 .
[0173] In one embodiment, the connecting member 2071 is provided with a cup holder 2072 and is integrally connected to the first tank body 207 . The cup holder 2072 is provided with a placement hole, and the shape of the placement hole is the same as or different from the cross-sectional shape of the first tank body 207 .
[0174] In one embodiment, the connecting member 2071 is provided with two cup holders 2072 , and the two cup holders 2072 are respectively provided with a first placement hole and a second placement hole, and the shapes of the first placement hole and the second placement hole are the same or different.
[0175] The first cell body 207 is a detection cup, and the second cell body 208 is a reagent cup. During detection, the reagent in the second cell body 208 is added to the first cell body 207 to prepare the sample to be detected and then the detection is performed.
[0176] An optical detection window is provided on the first cell body 207 for optical detection, such as optical detection by transmitted light or optical detection by scattered light.
[0177] The cross-sectional shapes of the first cell body 207 and the second cell body 208 are the same or different; or the heights of the first cell body 207 and the second cell body 208 are the same or different. The differentiated settings can achieve a fool-proof effect and facilitate assembly and identification.
[0178] The embodiment of the present application also provides a test kit, which includes a box body 100 and the aforementioned detection cup assembly, the box body 100 is provided with a mounting portion, the detection cup assembly is provided with a matching portion, and the mounting portion is connected to the matching portion.
[0179] The mating part may be a raised part or a recessed part provided on the side surface of the detection cup assembly, which is matingly connected with the mounting part; or the mating part may be a positioning flange provided on the detection cup assembly, which is matingly connected with the mounting part, for example, by using a flange structure to be hung with the insertion hole on the box body 100.
[0180] The detection cup assembly provided in this embodiment has a novel structure. Specific detection items can be equipped with corresponding required reagents on the cup holder 2072, which can greatly improve the detection efficiency and allow flexible selection of detection items.
[0181] Please refer to the seventeenth embodiment. Figures 1 to 6 An embodiment of the present application provides a test kit, which includes a box body 100 and an assembly seat 160.
[0182] The box body 100 includes a front cell 120, and the front cell 120 is equipped with a front cell electrode 121; the assembly seat 160 is connected to the box body 100, and the assembly seat 160 is equipped with a rear cell electrode 165, and the front cell electrode 121 and the rear cell electrode 165 are arranged at intervals.
[0183] In the embodiment of the present application, the axis of the front cell electrode 121 and the axis of the rear cell electrode 165 are roughly in the same straight line. Experimental verification shows that the detection accuracy is relatively high when the axis of the front cell electrode 121 and the rear cell electrode 165 are coaxial. Both the front cell electrode 121 and the rear cell electrode 165 are columnar electrodes, and the manufacturing process and assembly process are relatively simple.
[0184] The assembly seat 160 is provided with an axial drainage cavity 167 , and the axial drainage cavity 167 is connected with the front cell 120 through a microporous sheet 170 . The front cell electrode 121 and the rear cell electrode 165 are located on both sides of the microporous sheet 170 .
[0185] The microporous sheet 170 includes a sheet body 171 , which is provided with micropores 172 that allow cells to pass through one by one. The microporous sheet 170 is mounted on the assembly seat 160 or the box body 100 , or the microporous sheet 170 and the assembly seat 160 or the box body 100 are an integrally formed structure.
[0186] The axis of the front cell electrode 121 , the axis of the back cell electrode 165 , and the axis of the microporous sheet 170 are substantially in the same straight line.
[0187] The front cell electrode 121 protrudes, is flush with, or is recessed in the inner wall of the front cell 120; the rear cell electrode 165 protrudes, is flush with, or is recessed in the bottom wall of the axial drainage cavity 167. The two ends of the front cell electrode 121 and the rear cell electrode 165 are not particularly limited. The front cell electrode 121 and the rear cell electrode 165 are in contact with the test liquid during detection, and the outer ends of the front cell electrode 121 and the rear cell electrode 165 are used for external power supply components.
[0188] The box body 100 is provided with a mounting cavity 130 , and the assembly seat 160 includes an assembly tube 168 , and the mounting cavity 130 is coaxially connected with the assembly tube 168 .
[0189] The assembly cylinder 168 and the installation cavity 130 are snap-fitted, threaded, interference-fitted, laser-welded, or adhesively-fitted.
[0190] The front cell electrode 121 is disposed on the box body 100 and protrudes, is flush with, or is recessed on the outer side of the box body 100 . The rear cell electrode 165 is disposed on the assembly seat 160 and protrudes, is flush with, or is recessed on the outer side of the assembly seat 160 .
[0191] The embodiment of the present application also provides a sample detection device, which includes the aforementioned test kit and a detection seat that cooperates with the test kit, and the detection seat is used for sample analysis and detection.
[0192] Please refer to the eighteenth embodiment. Figures 1 to 6 An embodiment of the present application provides a test kit, which includes a box body 100 and a gripping portion 150 , wherein the gripping portion 150 is disposed on the box body 100 .
[0193] The gripping portion 150 may be disposed near the center of the side edge of the box body 100 , or near the center of the upper surface of the box body 100 .
[0194] There are two gripping portions 150 , which are disposed on two opposite sides of the box body 100 .
[0195] The gripping portion 150 protrudes from the upper surface or the side surface of the box body 100. The outer surface of the gripping portion 150 is provided with a buckle protrusion 151 or a buckle recess.
[0196] An anti-slip portion 152 is disposed on the top or outer side of the grip portion 150 .
[0197] The gripping portion 150 is an elastic member, and a recessed portion 154 is provided on the side of the box body 100 . The gripping portion 150 is connected with the recessed portion 154 in a cooperative manner.
[0198] The gripping portion 150 and the recessed portion 154 are connected integrally or detachably.
[0199] The gripping portion 150 is slidably connected to the recessed portion 154 so that the gripping portion 150 and the box body 100 can move relative to each other. The gripping portion 150 can be extended and retracted relative to the box body 100, which is convenient for storage and does not occupy space. The gripping portion 150 can be pulled out when needed.
[0200] The embodiment of the present application further provides a sample detection device, which includes the aforementioned test kit and a detection seat matched with the test kit, and the holding portion 150 is matched and connected with the detection seat.
[0201] Please refer to the nineteenth embodiment. Figures 1 to 6 An embodiment of the present application provides a test kit, which includes a box body 100 and a blocking portion 153.
[0202] The box body 100 includes at least one pool position (eg, a sample containing pool 105 ); the pool position is used to place a test tube (eg, a sample tube 205 ).
[0203] The blocking portion 153 is disposed at one side of the pool, and is used to hook the test tube cap (not shown) of the test tube to prevent the opened test tube cap from returning to cover the open end of the test tube.
[0204] In a specific embodiment, the blocking portion 153 may be protruding, flush, or recessed on the upper surface or side surface of the box body 100 .
[0205] In one embodiment, the blocking portion 153 includes a connecting piece connected to the box body 100 and a stopper portion extending from the connecting piece. A hook portion extending toward the box body 100 is provided at the end of the stopper portion.
[0206] In another embodiment, the side surface of the box body 100 protrudes outward to form a blocking portion 153; or the blocking portion 153 is a groove set on the upper surface of the box body 100; or the upper surface of the box body 100 is provided with a recessed portion, and the inner wall of the recessed portion forms the blocking portion 153, and the test tube cap of the test tube can be inserted into the recessed portion after being opened, and the size of the recessed portion can correspond to the size of the test tube cap to achieve a relatively tight fit.
[0207] The blocking portion 153 is integrally formed or detachably connected with the box body 100. Specifically, the blocking portion 153 is snap-fitted, plug-fitted, threadedly connected with the box body 100, or detachably connected with the box body 100 via screws / pins.
[0208] In other embodiments, the blocking portion 153 is also slidably connected to the box body 100 .
[0209] In the embodiment of the present application, the pool position (eg, the sample containing pool 105 ) is disposed close to the edge of the box body 100 , and the blocking portion 153 is disposed at the edge of the box body 100 .
[0210] The embodiment of the present application further provides a sample detection device, which includes the aforementioned test kit and a detection seat that cooperates with the test kit, and the detection seat is used for sample analysis.
[0211] The above are only implementation methods of the present application, and are not intended to limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.
Claims
1. An assembly seat, characterized in that: The assembly seat comprises: An assembly cylinder, which is a plastic assembly cylinder and is provided with an axial drainage cavity and a radial liquid outlet groove which are communicated with each other, and the radial liquid outlet groove is used to discharge the gas or liquid in the axial drainage cavity; a rear cell electrode connected to the assembly tube and extending toward the axial drainage cavity; The axial length of the radial liquid outlet groove in the axial drainage cavity is greater than or equal to the length of the rear cell electrode extending to the axial drainage cavity; The inner end of the assembly cylinder is provided with a microporous sheet allowing cells to pass through one by one.
2. The assembly seat according to claim 1, characterized in that: The outer surface of the assembly cylinder is provided with a recessed area connected with the radial liquid outlet groove to form a guide groove.
3. The assembly seat according to claim 1, characterized in that: The assembly cylinder is provided with a buckling portion, and the buckling portion is aligned with the radial liquid outlet groove.
4. The assembly seat according to claim 1, characterized in that: A first preset distance is formed between the inner end of the radial liquid outlet groove and the inner end of the assembly cylinder; The inner end of the rear cell electrode and the inner end of the assembly tube are at a second preset distance; The first preset distance is less than or equal to the second preset distance.
5. The assembly seat according to claim 1, characterized in that: The distance from the inner end of the back cell electrode to the microporous sheet is a third preset distance, and the third preset distance is 0.2-2 times the axial length of the axial drainage cavity.
6. The assembly seat according to claim 1, characterized in that: The inner end of the assembly cylinder is provided with a sinking platform, and the microporous sheet is cooperatively connected with the sinking platform.
7. The assembly seat according to claim 3, characterized in that: The assembly tube includes a rear pool tube, an end plate and an outer tube that are integrally connected. The rear pool tube is provided with the axial drainage cavity and the radial liquid outlet groove. The end plate radially connects the rear pool tube and the outer tube. The outer tube is sleeved on the outer periphery of the rear pool tube at intervals. The buckling portion is arranged corresponding to the positioning protrusion.
8. A kit, characterized in that: The kit comprises: The box body is provided with a front pool, a mounting cavity and a pressure action pool which are interconnected; The assembly seat according to any one of claims 1 to 7, wherein the assembly cylinder is connected to the installation cavity, the front pool is connected to the axial drainage cavity, and the front pool, the installation cavity, the axial drainage cavity, the radial liquid outlet groove, and the pressure action pool together constitute a drainage channel.
Citation Information
Patent Citations
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