Hook and blocking device

Abstract

The present invention discloses a hook and an occluder, wherein the hook is used to be fixed on the occluder, the occluder is formed by interweaving a first direction line and a second direction line, and the hook includes a positioning body and a hook portion; wherein the positioning body is provided with a first positioning portion and a second positioning portion, the first positioning portion and the second positioning portion are used to limit the hook to the first direction line and the second direction line respectively, or the first positioning portion and the second positioning portion are used to simultaneously limit the hook axially to the first direction line / the second direction line with different force application directions; the hook portion is formed by bending the positioning body, and the projection of the hook portion on the positioning body forms an angle ɑ with the axis of the positioning body, and the value range of the angle ɑ is greater than 0 degrees and less than 90 degrees. The hook provided by the present invention can be fixed to the occluder without other auxiliary parts such as sutures, and has excellent stability and firmness, and can increase the support strength of the occluder.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a hook and blocking device. Background Art

[0002] When atrial fibrillation occurs in patients, thrombus will form in the left atrial appendage. Thromboembolism will cause the risk of long-term disability or death. Left atrial appendage occlusion can reduce these risks by blocking the left atrial appendage. At present, the commonly used left atrial appendage occluders in clinical practice often have the problem of incomplete surface endothelialization, and thrombus is easily formed on the surface of the occluder, which then becomes one of the complications that seriously threaten the health and life of patients. In addition, the material of the existing left atrial appendage occluder is mostly nickel-titanium alloy. Due to its non-degradable characteristics, after the implantation operation, the stent will remain in the human body for a long time, causing a series of chronic problems such as occluder detachment, incomplete endothelialization of the occluder, thrombus related to the device, and device wear of the tissue around the atrial appendage.

[0003] The emergence of degradable left atrial appendage occluder can well alleviate the above problems, but the support and memory performance of degradable materials are poor, and there is a high risk of falling off after implantation; in order to prevent falling off, the relevant technology often adds a memory hook with better support to the degradable left atrial appendage occluder, and combines it with the degradable left atrial appendage occluder by suture, but this greatly increases the volume of non-degradable materials and increases the risk of memory hook falling off. How to effectively combine the degradable material in the occluder with a smaller volume of non-degradable materials to balance the above problems is a problem that urgently needs to be solved in the current technical field. Summary of the invention

[0004] In order to at least overcome the problems existing in the related art to a certain extent, one of the purposes of the present application is to provide a hook, which can be installed on the occluder through its own structure, without the need for other auxiliary parts such as sutures for fixation, and the hook has excellent stability and firmness, and can increase the support strength of the occluder;

[0005] Another object of the present application is to provide an occluder, on which the aforementioned hook is provided, the occluder has a stable occluding effect and a high supporting strength of the occluding disk. The specific technical solution is as follows:

[0006] According to a first aspect of an embodiment of the present application, there is provided a hook for fixing on an occluder, wherein the occluder is formed by interweaving a first direction line and a second direction line, and the hook comprises a hook having a positioning body and a hook portion; wherein:

[0007] The positioning body is provided with a first positioning portion and a second positioning portion, the first positioning portion and the second positioning portion are used to limit the hook on the first direction line and the second direction line respectively, or the first positioning portion and the second positioning portion are used to limit the axial direction of the hook on the first direction line / the second direction line at the same time with different force directions;

[0008] The hook portion is formed by bending the positioning body, and a projection of the hook portion on the positioning body forms an angle ɑ with an axis of the positioning body. The value range of the angle ɑ is greater than 0 degrees and less than 90 degrees.

[0009] In some embodiments, the first positioning portion is disposed along the axial direction of the positioning body.

[0010] In some embodiments, the first positioning portion includes at least two first positioning holes axially opened on the positioning body; the second positioning portion includes at least two second positioning holes opened between the first positioning holes, and the first positioning hole and the second positioning hole are used to pass through the first direction line and the second direction line respectively; preferably, the connecting line between the second positioning holes and the connecting line between the first positioning holes have an angle β, and the value of the angle β is equal to the value of the angle between the first direction line and the second direction line.

[0011] Preferably, there are two first positioning holes, and the two first positioning holes are respectively opened at two ends of the positioning body; preferably, bulging parts are formed on the positioning body corresponding to the first positioning hole and the second positioning hole.

[0012] In some embodiments, a hook portion is provided beside each of the first positioning holes, and the hook portion is formed by extending and bending the positioning body, and the bending angle γ formed between each of the hook portions and the positioning body is the same.

[0013] In some embodiments, the positioning body has a first side and a second side relative to each other, the first positioning portion includes a first part and a second part respectively arranged on the first side and the second side, the first part is detachably connected to the second part, and the first side and the second side can be bent toward each other so that the positioning body is fixed on the first direction line / second direction line through the buckling of the first part and the second part.

[0014] In some embodiments, the first portion and the second portion are hooks that can be fastened to each other.

[0015] In some embodiments, the first portion is a plurality of buckle grooves axially opened on the first edge, and the second portion is a connecting protrusion corresponding to and matching the buckle grooves one by one.

[0016] In some embodiments, the second positioning portion includes at least one pair of barbs disposed opposite to each other, and the two barbs are disposed along the axial direction of the positioning body; preferably, the second positioning portion includes two pairs of barbs, and the two pairs of barbs are disposed flush in the axial direction.

[0017] In some embodiments, the hook portion is formed by cutting and then bending the positioning body; preferably, the hook portion is axially cut from the end of the positioning body into a strip body whose root is connected to the positioning body, and the strip body is bent in a bending direction opposite to the barb.

[0018] In some embodiments, a projection of the hook portion on the positioning body is located on a first side or a second side of an axis of the positioning body, wherein the first side is an opposite side to the second side.

[0019] In some embodiments, when the projection of the hook on the positioning body is located on the first side of the axis of the positioning body, the first positioning portion is used to limit the axial direction of the hook to the first direction line; when the projection of the hook on the positioning body is located on the second side of the axis of the positioning body, the first positioning portion is used to limit the axial direction of the hook to the second direction line.

[0020] According to a second aspect of an embodiment of the present application, there is provided an occluder formed by interweaving a first direction line and a second direction line, comprising:

[0021] A fixing plate, provided with a plurality of the hooks, for fixing in the left atrial appendage through the hooks;

[0022] The occluding disk has a diameter larger than the fixing disk and is used for occluding the left atrial appendage.

[0023] In some embodiments, the hook includes the hook, the first positioning portion of the hook includes two first positioning holes axially opened at both ends of the positioning body, the second positioning portion of the hook includes two second positioning holes opened between the first positioning holes, the connecting line between the second positioning holes and the connecting line between the first positioning holes have an angle β, and the value of the angle β is equal to the value of the angle between the first direction line and the second direction line;

[0024] A hook portion is provided beside each of the first positioning holes, and the hook portion is formed by extending and bending the positioning body, and the bending angle and bending direction of each of the hook portions are the same;

[0025] The first positioning portion of the hook is disposed on a first direction line designated on the fixing plate, and the second positioning portion of the hook is disposed on a second direction line corresponding to the second positioning portion, and the hooks have the same hanging direction.

[0026] In some embodiments, the hooks are respectively disposed on the first direction line and the second direction line of the fixed plate, and the hooks have the same hanging direction.

[0027] In some embodiments, the hooks are arranged in a wavy line along the circumference of the fixing plate.

[0028] In some embodiments, the positioning body has a first side and a second side opposite to each other, the first positioning portion comprises a first part and a second part respectively arranged on the first side and the second side, and the first part is detachably connected to the second part;

[0029] The second positioning portion comprises at least a pair of barbs disposed opposite to each other, and the two barbs are disposed along the axial direction of the positioning body;

[0030] The positioning body is wrapped around the designated first direction line / the designated second direction line after the first side and the second side are bent toward each other, the first part and the second part of the positioning body are interlocked so that the positioning body is sleeved on the designated first direction line / the designated second direction line, and the barbs are pierced and fixed on the designated first direction line / the designated second direction line by external pressure;

[0031] The first direction line intersects with the second direction line to form a node, and the two barbs are respectively fixed on both sides of the node on the designated first direction line / designated second direction line.

[0032] The technical solution provided by the embodiments of the present application has at least the following beneficial effects:

[0033] The hook of the present application can be directly fixed on the occluder based on the positioning body without other auxiliary structures such as sutures, thereby reducing the proportion of non-degradable materials in the occluder. Specifically, the positioning body includes a first positioning part and a second positioning part. The positioning body can be fixed on the first direction line through the first positioning part, and fixed on the second direction line through the second positioning part; or, the positioning body can be fixed on the second direction line through the first positioning part, and fixed on the first direction line through the second positioning part. Based on the first direction line and the second direction line being interwoven and woven into the occluder, the first positioning part and the second positioning part can stably fix the hook on the occluder; in addition, the first positioning part and the second positioning part can be fixed on the same direction line at the same time under the premise of different force application directions, for example, they can be fixed on the first direction line at the same time, or they can be fixed on the second direction line at the same time, so that the hook can be stably fixed on the occluder under the complementary condition;

[0034] The present application is based on the fact that the hook is formed by bending the positioning body, and the hook is axially fixed on the first direction line / the second direction line. The fixing direction of the positioning body on the occluder disk is fixed with the axis parallel to the first direction line or the second direction line. When the value range of the angle ɑ between the projection on the positioning body and the axis of the positioning body is greater than 0 degrees and less than 90 degrees, it can be ensured that when the hook is fixed on the occluder, the hook and the left atrial appendage have a stable fixed angle.

[0035] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and, together with the description, serve to explain the principles of the present application.

[0037] Figure 1 A schematic diagram of the installation method of the hook provided in Example 1 of the present invention on the occluder;

[0038] Figure 2 A schematic diagram of the structure of a hook provided in Example 1 of the present invention;

[0039] Figure 3 for Figure 2 Side view of the middle hook;

[0040] Figure 4 A schematic diagram of the structure of another hook provided in Embodiment 1 of the present invention;

[0041] Figure 5 A schematic diagram of the installation method of the hook provided in Example 2 of the present invention on the occluder;

[0042] Figure 6 A schematic diagram of the structure of a hook provided in Example 2 of the present invention;

[0043] Figure 7 for Figure 6 A top view of the middle hook;

[0044] Figure 8 for Figure 7 A partial enlarged schematic diagram of the first positioning portion at position A in the middle;

[0045] Fig. 9 A schematic diagram of the deployment of the hook provided in Embodiment 2 of the present invention;

[0046] Fig.10 A schematic diagram of the connection relationship between the hook and the first direction line / the second direction line provided in Embodiment 2 of the present invention;

[0047] Fig.11 for Fig.10Sectional view along line AA;

[0048] Fig.12 A schematic diagram of the structure of an occluder provided by an embodiment of the present invention;

[0049] Fig.13 A force analysis diagram of a hook arrangement in one embodiment of the present invention;

[0050] Fig.14 This is a schematic diagram of the installation position of the occluder in the left atrial appendage in one embodiment of the present invention;

[0051] Fig.15 It is a schematic diagram of the side contour line of an occluder in one embodiment of the present invention;

[0052] Fig.16 It is a schematic diagram of releasing the occluder through the delivery sheath in one embodiment of the present invention;

[0053] Fig.17 This is a schematic diagram of the occluder being recovered through a delivery sheath in one embodiment of the present invention.

[0054] Description of reference numerals:

[0055] 100, first hook; 110, positioning body; 111, first positioning portion; 1111, first part; 1112, second part; 112, second positioning portion; 1121, barb; 120, hook portion; 130, bulging portion;

[0056] 200, second hook;

[0057] 300, occluder; 310, fixing plate; 320, occluding plate; 330, first direction line; 340, second direction line;

[0058] 400, left atrial appendage;

[0059] 500. Delivery sheath. DETAILED DESCRIPTION

[0060] Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, unless otherwise indicated, the same numbers in different drawings represent the same or similar elements. The implementations described in the following exemplary embodiments do not represent all implementations consistent with the present application. Instead, they are merely examples of methods consistent with some aspects of the present application as detailed in the appended claims.

[0061] In the related art, a hook with memory properties is usually provided on the degradable occluder to increase the supporting strength and prevent the occluder from falling off. However, auxiliary structures such as sutures are usually required to fix the hook to the occluder, which will increase the proportion of non-degradable materials. At the same time, the additional components increase the risk of the memory hook and the occluder falling off, or there are structural design defects that are not conducive to the effective combination of the hook and the occluder.

[0062] Based on the analysis and discovery of the above problems, this application is proposed.

[0063] The present application provides a hook for fixing on an occluder, wherein the occluder is formed by interweaving a first direction line and a second direction line, and the hook comprises a hook having a positioning body and a hook portion; wherein:

[0064] The positioning body is provided with a first positioning portion and a second positioning portion, the first positioning portion is used to limit the axial direction of the hook on the first direction line, and the second positioning portion is used to limit the axial direction of the hook on the second direction line; or the first positioning portion and the second positioning portion are used to limit the axial direction of the hook on the first direction line / the second direction line at the same time with different force application directions;

[0065] The hook portion is formed by bending the positioning body, and a projection of the hook portion on the positioning body forms an angle ɑ with an axis of the positioning body. The value range of the angle ɑ is greater than 0 degrees and less than 90 degrees.

[0066] The hook of the present application can be directly fixed on the occluder based on the positioning body without other auxiliary structures such as sutures, thereby reducing the proportion of non-degradable materials in the occluder. Specifically, the positioning body includes a first positioning part and a second positioning part. The positioning body can be fixed on the first direction line through the first positioning part, and fixed on the second direction line through the second positioning part; or, the positioning body can be fixed on the second direction line through the first positioning part, and fixed on the first direction line through the second positioning part. Based on the first direction line and the second direction line being interwoven and woven into the occluder, the first positioning part and the second positioning part can stably fix the hook on the occluder; in addition, the first positioning part and the second positioning part can be fixed on the same direction line at the same time under the premise of different force application directions, for example, they can be fixed on the first direction line at the same time, or they can be fixed on the second direction line at the same time, so that the hook can be stably fixed on the occluder under the complementary condition;

[0067] The present application is based on the fact that the hook is formed by bending the positioning body, and the hook is axially fixed on the first direction line / the second direction line. The fixing direction of the positioning body on the occluder disk is fixed with the axis parallel to the first direction line or the second direction line. When the value range of the angle ɑ between the projection on the positioning body and the axis of the positioning body is greater than 0 degrees and less than 90 degrees, it can be ensured that when the hook is fixed on the occluder, the hook and the left atrial appendage have a stable fixed angle.

[0068] In some embodiments, the first positioning portion includes at least two first positioning holes axially opened on the positioning body; the second positioning portion includes at least two second positioning holes opened between the first positioning holes, the first positioning hole and the second positioning hole are used to penetrate the first direction line and the second direction line respectively; preferably, the line connecting the second positioning holes and the line connecting the first positioning holes have an angle β, and the value of the angle β is equal to the value of the angle between the first direction line and the second direction line. In these embodiments, the first positioning portion and the second positioning portion are respectively a plurality of positioning holes arranged on the positioning body, wherein the angle between the line connecting each first positioning hole and the line connecting each second positioning hole is the same as the angle between the first direction and the second direction line, so that, for example, the first direction line can be smoothly inserted into the first positioning hole, and the second direction line can be smoothly inserted into the second positioning hole, based on the cross setting of the first direction line and the second direction line, therefore, the first positioning portion and the second positioning portion can limit the hook on the occluder in different directions, and the hook will not be detached from the occluder when the occluder is not damaged.

[0069] Preferably, there are two first positioning holes, and the two first positioning holes are respectively opened at both ends of the positioning body; preferably, a bulge is formed on the positioning body corresponding to the first positioning hole and the second positioning hole. In these embodiments, in order to reduce production costs and balance force stability, two first positioning holes and two second positioning holes can be set, wherein the first positioning hole and the second positioning hole are opened on the bulge of the positioning body to increase the force strength of the positioning body and improve its service life.

[0070] In some embodiments, a hook is provided beside each of the first positioning holes, and the hook is formed by extending and bending the positioning body, and the bending angle γ formed between each hook and the positioning body is the same. In these embodiments, multiple hooks can be provided, and the position of the hook is not limited to being provided beside the first positioning hole. However, if the hook is provided beside the first positioning hole, since the first positioning hole can be fixed on the first direction line when in use, the stability is better, and the stable connection of the hook to the left atrial appendage can be ensured. In addition, the bending angle γ formed between the hook and the positioning body should be the same, so that when the left atrial appendage is fixed, each hook can ensure that the force direction is consistent, increase the fixing strength in the left atrial appendage, and prevent slipping.

[0071] In some embodiments, the positioning body has a first side and a second side that are opposite to each other, the first positioning portion includes a first part and a second part that are respectively arranged on the first side and the second side, the first part and the second part are detachably connected, and the first side and the second side can be bent toward each other so that the positioning body is fixed on the first direction line / the second direction line through the buckling of the first part and the second part. In these embodiments, based on the buckling of the first part and the second part in the first positioning portion, the positioning body is cylindrically sleeved on the first direction line / the second direction line when in use, so as to be axially limited on the first direction line / the second direction line.

[0072] In some embodiments, the first portion and the second portion are hooks that can be fastened to each other.

[0073] In some embodiments, the first portion is a plurality of buckle grooves axially opened on the first edge, and the second portion is a connecting protrusion corresponding to and matching the buckle grooves one by one.

[0074] In some embodiments, the second positioning portion includes at least one pair of barbs disposed opposite to each other, and the two barbs are disposed along the axial direction of the positioning body. In these embodiments, the second positioning portion radially limits the positioning body on the corresponding first direction line / second direction line through the barbs disposed opposite to each other, that is, the hook is limited in a direction different from that of the first positioning portion, so that the hook can be stably fixed on the first direction line / second direction line. Preferably, the second positioning portion includes two pairs of barbs, and the two pairs of barbs are flushly disposed in the axial direction. Of course, in order to further increase the connection stability between the hook and the occluder, multiple pairs of barbs can be provided. Based on the volume of the positioning body and other actual conditions, two pairs of flush barbs can be provided to ensure the stability of the connection.

[0075] In some embodiments, the hook portion is formed by bending the positioning body after cutting. In these embodiments, the hook portion is also formed by bending the positioning body, but the difference is that the hook portion in these embodiments is formed by bending the positioning body after cutting. Preferably, the hook portion is axially cut from the end of the positioning body into a strip body whose root is connected to the positioning body, and the strip body is bent in a bending direction opposite to the barb.

[0076] In some embodiments, the projection of the hook portion on the positioning body is located on a first side or a second side of the axis of the positioning body, wherein the first side is the opposite side of the second side.

[0077] In some embodiments, when the projection of the hook on the positioning body is located on the first side of the axis of the positioning body, the first positioning portion is used to limit the axial direction of the hook to the first direction line; when the projection of the hook on the positioning body is located on the second side of the axis of the positioning body, the first positioning portion is used to limit the axial direction of the hook to the second direction line.

[0078] According to a second aspect of an embodiment of the present application, there is provided an occluder formed by interweaving a first direction line and a second direction line, comprising:

[0079] A fixing plate, provided with a plurality of the hooks, for fixing in the left atrial appendage through the hooks;

[0080] The occluding disk has a diameter larger than the fixing disk and is used for occluding the left atrial appendage.

[0081] In these embodiments, the occluder is fixed in the left atrial appendage based on the above-mentioned hook provided on the fixing plate of the occluder. Based on the structural characteristics of the hook itself, it can be directly fixed on the occluder without other auxiliary structures, and is firmly connected to the occluder and is not easy to fall off, thereby enhancing the occluding effect of the occluder.

[0082] In some embodiments, the hooks are respectively provided on the first direction line and the second direction line of the fixed disk, and the hooks have the same hanging direction. In these embodiments, whether the positioning body is fixed on the fixed disk in a strip shape or a curled cylindrical shape, based on the different bending directions of the hook in the hook, that is, when the hook is axially fixed on the first direction line, the projection of the hook on the positioning body is located on the first side of the axis of the positioning body, and when the hook is axially fixed on the second direction line, the projection of the hook on the positioning body is located on the second side of the axis of the positioning body, and at this time, the hanging direction of the hook is the same, therefore, it can be understood that two mirror-symmetrical hooks are axially fixed on the first direction line and the second direction line respectively, and the hooks are respectively provided in two directions, and both can form two forms. When in use, the hooks of the two forms are respectively axially fixed on the first direction line and the second direction line, and the hooks of the two forms have the same hanging direction on the left atrial appendage, so that the hanging force can be applied in the same direction to prevent the occluder from being unhooked, and the hooks are respectively provided on the first direction line and the second direction line, which is equivalent to providing reinforcing ribs in both directions, thereby greatly enhancing the supporting force of the occluder.

[0083] In some embodiments, the hooks are arranged in a wavy line along the circumference of the fixed disk. In these embodiments, since the fixed disk is woven from the first direction line and the second direction line, the first direction line and the second direction line will form a plurality of diamond grids, and the wavy line arrangement shape of the hooks and the second hooks makes them necessarily located on the adjacent two sides of a certain diamond grid or close to the adjacent vertices of the diamond grid, which can increase the support strength of the occluder and make the occlusion effect more stable.

[0084] In some embodiments, the positioning body has a first side and a second side opposite to each other, the first positioning portion comprises a first part and a second part respectively arranged on the first side and the second side, and the first part is detachably connected to the second part;

[0085] The second positioning portion comprises at least a pair of barbs disposed opposite to each other, and the two barbs are disposed along the axial direction of the positioning body;

[0086] The positioning body is wrapped around the designated first direction line / the designated second direction line after the first side and the second side are bent toward each other, the first part and the second part of the positioning body are interlocked so that the positioning body is sleeved on the designated first direction line / the designated second direction line, and the barbs are pierced and fixed on the designated first direction line / the designated second direction line by external pressure;

[0087] The first direction line intersects with the second direction line to form a node, and the two barbs are respectively fixed on both sides of the node on the specified first direction line / specified second direction line. In these embodiments, when two passes are arranged on both sides of the node, the stability of the connection between the hook and the fixed plate can be further improved.

[0088] In order to more clearly understand the hook and occluder provided in the embodiments of the present disclosure, specific embodiments of the present invention will be described below with reference to the accompanying drawings. In this process, the thickness of the wires or the sizes of the structural elements shown in the drawings may be shown in an exaggerated manner for the sake of clarity and convenience of the description.

[0089] See also Figure 1, This embodiment provides a hook, which is formed by cutting and heat treating a memory metal material, and is used in conjunction with an occluder 300 formed by weaving wires. The memory metal material can be either a non-degradable memory material or a degradable memory metal material, such as nickel-titanium wire, polymer wire or degradable magnesium alloy. A developing coating is attached to the surface of the hook, which is convenient for doctors to see the position of the hook in the left atrial appendage under angiography during operation, so as to determine whether the occluder is stable; the hook is mainly fixed to the occluder 300 by threading the wire, and the occluder 300 is interwoven by a first direction line 330 and a second direction line 340, including an occluder outer layer and a flow-blocking membrane; 3: forming ring, hook and welding ball; wherein, the occluder outer layer as a skeleton component includes a fixing disk and a occluding disk formed by weaving and heat treating a degradable wire; the flow-blocking membrane is fixed to the occluder outer layer by degradable wires, thereby forming a flow-blocking isolation effect; the hook is connected and fixed to the fixing disk of the occluder outer layer by perforation or pressing.

[0090] See also Figure 2-4 as well as Figure 6-9 The hook has a positioning body 110 and a hook portion 120; the positioning body 110 is provided with a first positioning portion 111 and a second positioning portion 112, the first positioning portion 111 and the second positioning portion 112 are used to limit the hook on the first direction line 330 and the second direction line 340 respectively, or the first positioning portion 111 and the second positioning portion 112 are used to simultaneously limit the axial direction of the hook on the first direction line 330 / the second direction line 340 with different force directions; the hook portion is formed by bending the positioning body 110, and the projection of the hook portion 120 on the positioning body 110 forms an angle ɑ with the axis of the positioning body 110, and the value range of the angle ɑ is greater than 0 degrees and less than 90 degrees.

[0091] The hook of the present application can be directly fixed on the occluder 300 based on the positioning body 110 without other auxiliary structures such as sutures, thereby reducing the proportion of non-degradable materials in the occluder 300. Specifically, the positioning body 110 includes a first positioning portion 111 and a second positioning portion 112. The positioning body 110 can be fixed on the first direction line 330 through the first positioning portion 111, and fixed on the second direction line 340 through the second positioning portion 112; or, the positioning body 110 can be fixed on the second direction line 340 through the first positioning portion 111, and fixed on the first direction line 340 through the second positioning portion 112. Based on the first direction line 330 and the second direction line 340 being interwoven and woven into the occluder 300, the first positioning portion 111 and the second positioning portion 112 can stably fix the hook on the occluder 300; in addition, the first The positioning portion 111 and the second positioning portion 112 can be fixed on the same direction line at the same time under the premise of different force directions, for example, they are fixed on the first direction line 330 at the same time, or they are fixed on the second direction line 340 at the same time, so that the hook is stably fixed on the occluder 300 under the condition of complementarity; the present application is based on the fact that the hook portion 120 is bent by the positioning body 110, and the hook is axially fixed on the first direction line 330 / the second direction line 340, then the fixing direction of the positioning body 110 on the occluder disk 300 is fixed with the axis parallel to the first direction line 330 or the second direction line 340, and when the value range of the angle ɑ between the projection on the positioning body 110 and the axis of the positioning body 110 is greater than 0 degrees and less than 90 degrees, it can be ensured that when the hook is fixed on the occluder 300, the hook portion 120 and the left atrial appendage 400 have a stable fixed angle.

[0092] The hook of the present application is based on the positioning body 110, which can enable the hook to be directly fixed on the occluder 300 without other auxiliary structures such as sutures, thereby reducing the proportion of non-degradable materials in the occluder 300. Specifically, the positioning body 110 includes a first positioning portion 111 and a second positioning portion 112. The positioning body 110 can be fixed on the first direction line 330 through the first positioning portion 111, and the second positioning portion 112 is fixed on the second direction line 340; or, the positioning body 110 can be fixed on the second direction line 340 through the first positioning portion 111, and fixed on the first direction line 330 through the second positioning portion 112. Based on the first direction line 330 and the second direction line 340 being interwoven and woven into the occluder 300, the first positioning portion 111 and the second positioning portion 112 can stably fix the hook on the occluder 300; in addition, the first positioning portion 111 and the second positioning portion 112 can be fixed on the same direction line at the same time under the premise of different force directions, for example, they can be fixed on the first direction line 330 at the same time, or they can be fixed on the second direction line 340 at the same time, so that the hook can be stably fixed on the occluder 300 under the condition of complementarity; based on The hook portion 120 is formed by bending the positioning body 110, and the hook is axially fixed on the first direction line 330 / the second direction line 340. The fixing direction of the positioning body 110 on the occluder 300 is fixed with the axis parallel to the first direction line 330 or the second direction line 340. When the value range of the angle ɑ between the projection on the positioning body 110 and the axis of the positioning body 110 is greater than 0 degrees and less than 90 degrees, it can be ensured that when the hook is fixed on the occluder 300, the hook portion 120 and the left atrial appendage 400 have a stable fixed angle.

[0093] Embodiment 1: In the first aspect, the present application will firstly describe the hook connected to the fixing plate by perforation:

[0094] See also Figure 2 and Figure 3 In the present embodiment, the positioning body 110 is roughly strip-shaped, and two ends of the positioning body 110 are respectively formed with two bulging parts 130 located on the axis of the positioning body, and the middle part of the two ends also has two bulging parts 130 protruding to both sides, wherein the first positioning part 111 is a first positioning hole opened on the two bulging parts 130 at the ends, and the second positioning part 112 is a second positioning hole opened on the two bulging parts 130 in the middle, and the connecting line between the second positioning holes and the connecting line between the first positioning holes have an angle β, and the value of the angle β is equal to the value of the angle between the first direction line and the second direction line. Among them, the first positioning hole is used to axially penetrate on the first direction line 330 or the second direction line 340, and the second positioning hole is used to penetrate on the other direction line. For example, when the first positioning hole is penetrated on the first direction line 330, the second positioning hole is penetrated on the second direction line 340; of course, in actual use, please refer to Figure 1, the first positioning hole can also be penetrated at the junction of the first direction line 330 and the second direction line 340, that is, the first positioning hole can be penetrated on the first direction line 330 and the second direction line 340 at the same time, so as to be more stably fixed on the occluder 300. In this embodiment, the bulging part 130 can expand the area on the positioning body 110 where it is located, which is convenient for opening the first positioning hole or the second positioning hole, and at the same time can increase the strength of the positioning body 110. Of course, the bulging part 130 is not necessarily provided, and the first positioning hole or the second positioning hole can be directly opened at the corresponding position of the positioning body 110. In addition, based on the small range of deformation of the first direction line 330 and the second direction line 340, the angle between the connecting line between the second positioning holes and the connecting line between the first positioning holes can be approximately equal to the value of the angle between the first direction line and the second direction line.

[0095] The hook portion 120 is formed by bending the positioning body 110. Specifically, the ... Figure 1-2 and Figure 4 , Figure 1-2 and Figure 4 The orientation of each component is consistent, for example, the left or right side) of the positioning body 110 is extended and bent, and the bending angle γ formed between each hook portion 120 and the positioning body 110 is the same. In this embodiment, there are two first positioning holes, and accordingly, two hook portions 120 are provided. Figure 2 and Figure 3 , the bending angle γ formed between the two hooks 120 and the positioning body 110 is the same, that is, from the bending direction, the projections of the two hooks 120 on the positioning body 110 form an angle ɑ with the axis of the positioning body 110, and the value range of the angle ɑ is greater than 0 degree and less than 90 degrees. From the bending angle, the bending angles of the two hooks 120 relative to the positioning body 110 are both γ. Setting the bending angle and the bending direction to be the same can ensure that when in use, the hooking direction of the hook 120 on the left atrial appendage 400 is consistent, and the resultant force is larger, thereby increasing the effective occlusion of the left atrial appendage by the occluder 300.

[0096] In this example, please continue to refer to Figure 1-2 and Figure 4 , when the projection of the hook 120 on the positioning body 110 forms an angle ɑ with the axis of the positioning body 110, and the value range of the angle ɑ is greater than 0 degrees and less than 90 degrees, the bending direction of the hook 120 can be two, that is, the projection of the hook 120 on the positioning body 110 is located on the first side or the second side of the axis of the positioning body 110, wherein the first side is the opposite side of the second side. Figure 2 As shown, it is assumed that when the projection of the hook portion 120 on the positioning body 110 is located on the first side of the axis of the positioning body 110 ( Figure 2The hook formed when the hook portion 120 is axially limited on the first direction line 330 through the first positioning portion 111 is the first hook 100, and the first hook 100 is used to be axially limited on the first direction line 330 through the first positioning portion 111; when the projection of the hook portion 120 on the positioning body 110 is located on the second side of the axis of the positioning body 110 ( Figure 2 The hook formed when the first hook 200 is axially limited to the second direction line 340 through the first positioning portion 111 is a second hook 200.

[0097] Embodiment 2: The second aspect of the present application will describe the hook fixed to the fixing plate 310 by pressing:

[0098] See also Figure 5-11 In this embodiment, the length-to-width ratio of the positioning body 110 is greater than 1:1, and the two long sides of the positioning body 110 are respectively the first side and the second side that are opposite to each other. The first positioning portion 111 includes a first portion 1111 and a second portion 1112 that are respectively arranged on the first side and the second side. The first portion 1111 and the second portion 1112 are detachably connected, and the first side and the second side can be bent toward each other so that the positioning body 110 is fixed on the first direction line 330 / the second direction line 340 through the buckling of the first portion 1111 and the second portion 1112. That is, in this embodiment, the shape of the positioning body 110 in the use state can be considered to be a cylindrical shape that can be opened and closed in the axial direction, wherein the opening and closing method is mainly realized by the cooperation of the first portion 1111 and the second portion 1112, please refer to Figure 7-8 , the first part 1111 and the second part 1112 can be hooks that can be fastened to each other; please refer to Fig. 9 The first part 1111 may also be a plurality of buckle grooves axially opened on the first side, and the second part 1112 may be a connecting protrusion corresponding to and matching the buckle grooves one by one.

[0099] See also Figure 6 The second positioning portion 112 includes at least one pair of barbs 1121 disposed opposite to each other, and the two barbs 1121 are disposed along the axial direction of the positioning body. Of course, the second positioning portion 112 may include multiple pairs of barbs 1121, for example, the second positioning portion 112 includes two pairs of barbs 1121, and the two pairs of barbs 1121 are disposed flush in the axial direction of the positioning body 110.

[0100] In this embodiment, the structure of the hook portion 120 is shown in FIG. Figure 6 , which is formed by cutting and then bending the positioning body 110. Specifically, the hook portion 120 is axially cut from the end of the positioning body 110 to form a strip body whose root is connected to the positioning body 110, and the strip body is bent in a bending direction opposite to the barb 1121.

[0101] In this embodiment, two types of hooks can be formed according to the projection of the hook portion 120 on the positioning body 110 being located on different sides of the axis of the positioning body 110. When the projection of the barb 120 on the positioning body 110 is located on the first side of the axis of the positioning body 110, the first hook 100 is formed. Figure 5 or Figure 6 The first side is the right side of the axis of the positioning body 110. At this time, the root of the hook 120 is on the left side of the axis of the positioning body 110. When the projection of the barb 120 on the positioning body 110 is located on the second side of the axis of the positioning body 110, a second hook 200 is formed. Please refer to Figure 5 The second side is the left side of the axis of the positioning body 110 , and at this time, the root of the hook 120 is on the right side of the axis of the positioning body 110 .

[0102] When using, please refer to Figure 10-11 , the first side and the second side of the positioning body 110 are bent toward each other, and the positioning body 110 is sleeved on the first direction line 330 / the second direction line 340. At this time, the barb 1121 is bent toward the fixed disk 310, and the hook portion 120 is bent away from the fixed disk 310, that is, the bending directions of the barb 1121 and the hook portion 120 are different. At this time, the barb 1121 of the second positioning portion 112 is pressed into the corresponding first direction line 330 / the second direction line 340 by pressing, and finally, the positioning body is axially buckled on the first direction line 330 / the second direction line 340 through the first part 1111 and the second part 1112 of the first positioning portion 111, so that the hook is fixed on the fixed disk 310.

[0103] Embodiment 3: The third aspect of the present application will describe an occluder 300:

[0104] See also Fig.12 The occluder 300 is formed by interweaving a first direction line 330 and a second direction line 340, and includes a fixed disk 310 and an occluding disk 320. The fixed disk 310 is provided with a plurality of hooks for fixing in the left atrial appendage 400 through the hooks; the occluding disk 320 has a diameter greater than that of the fixed disk 310 and is used for occluding the left atrial appendage 400.

[0105] The hook of this embodiment is the hook described in the first aspect, including a first hook 100 and a second hook 200. The first hook 100 and the second hook 200 each have two hook portions 120 disposed up and down, and the included angles ɑ between the projection of the hook portion 120 on the positioning body 110 and the axis of the positioning body 110 are equal, and the bending angles γ between the hook portion 120 and the positioning body 110 are also equal. Fig.13In the process of preparing the fixing plate 300, the first direction line 330 is passed through the two first positioning holes of the first hook 100, and the second direction line 340 is passed through the two second positioning holes of the first hook 100. Since the first direction line 330 and the second direction line 340 form a cross structure, the first hook 100 is fixed; the fixing principle of the second hook 200 is the same. When the first positioning hole of the second hook 200 is penetrated on the second direction line 340, the second positioning hole is penetrated on the first direction line 330. When using, please refer to Fig.14 When the occluder 300 is implanted, the fixing plate 310 will be compressed by the left atrial appendage 400 of different shapes, causing the fixing plate 310 to deform. Fig.15 Since the fixing plate 310 and the hook are relatively fixed, the deformation of the fixing plate 310 will drive the hook to fix different positions in the left atrial appendage 400, thereby making the occlusion stable.

[0106] In this way, the fixing method of the structure itself completely eliminates the need for other auxiliary components for fixing, improves the stability and firmness of the hook, and greatly reduces the volume of non-degradable materials. In addition, the first hook 100 and the second hook 200 are spaced apart on the fixing plate 310 of the occluder 300, and the plurality of hooks are arranged in a wavy line on the fixing plate 310, and the adjacent first hook 100 and the second hook 200 form two adjacent sides of a shape similar to a rhombus, which increases the support strength of the occluding plate 320 and makes the occluding effect more stable.

[0107] Fig.16 is a schematic diagram of the occluder 300 being released through the delivery sheath 500. Fig.17 This is a schematic diagram of the occluder 300 being recovered through the delivery sheath 500. Since the hook portion 120 has memory, when the occluder 300 is released from the delivery sheath 500, it will immediately return to the finalized J-shaped structural state; when the occluder 300 is recovered into the delivery sheath 500, the hook portion 120 is subjected to a certain force and becomes a linearly expanded state in the delivery sheath 500.

[0108] Embodiment 4: The fourth aspect of the present application will describe another occluder 300:

[0109] The occluder 300 in this embodiment is different from the occluder 300 provided in the fourth aspect in that the hook adopts the hook described in the second aspect, that is, the positioning body 110 of the hook has a first side and a second side opposite to each other, the first positioning portion 111 includes a first part 1111 and a second part 1112 respectively arranged on the first side and the second side, and the first part 1111 and the second part 1112 are detachably connected; the second positioning portion 112 includes at least a pair of barbs 1121 arranged opposite to each other, and the two barbs 1121 are arranged along the axial direction of the positioning body; the positioning body 110 is wrapped around the designated first direction line 330 / designated second direction line 340 after the first side and the second side are bent opposite to each other, the first part 1111 and the second part 1112 of the first positioning portion 111 are interlocked to make the positioning body 110 sleeved on the designated first direction line 330 / designated second direction line 340, and the barbs 1121 are pierced and fixed on the designated first direction line 330 / designated second direction line 340 under external pressure. In order to improve the stability of the hook, based on the intersection of the first direction line 330 and the second direction line 340 to form a node, the two barbs 1121 can be fixed on both sides of the node on the designated first direction line 330 / designated second direction line 349 respectively.

[0110] Similarly, like the occluder 300 described in the third aspect, the hook in this embodiment also includes a first hook 100 and a second hook 200, the hook-shaped directions of the hook portions 120 of the first hook 100 and the second hook 200 are opposite, and the first hook 100 and the second hook 200 are arranged on the skeleton of the occluder 100 in an up-down staggered manner and arranged at intervals, so that the hooks on the fixing plate 310 can be evenly and effectively distributed.

[0111] It is understood that the same or similar parts in the above embodiments can refer to each other, and the content not described in detail in some embodiments can refer to the same or similar content in other embodiments. It should be noted that the terms in the description of this application are defined in consideration of the functions in the present invention, and may vary according to the intentions or conventions of the users and operators. Therefore, the definition of such terms should be defined based on the content of this specification as a whole.

[0112] For example, the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0113] In the description of this specification, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0114] The description with reference to the terms "one embodiment", "some embodiments", "examples", "specific examples", or "some examples" means that the specific features, structures, materials, or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described may be combined in any one or more embodiments or examples in a suitable manner.

[0115] Although the embodiments of the present application have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be understood as limitations on the present application. Ordinary technicians in this field can change, modify, replace and modify the above embodiments within the scope of the present application.

Claims

1. A hook, characterized in that: Used to be fixed on the occluder, the occluder is formed by interweaving the first direction line and the second direction line, and the hook includes a positioning body and a hook part; wherein, The positioning body is provided with a first positioning portion and a second positioning portion, and the first positioning portion and the second positioning portion are used to limit the hook to the first direction line and the second direction line respectively. The hook portion is formed by bending the positioning body, and the projection of the hook portion on the positioning body forms an angle ɑ with the axis of the positioning body, and the value range of the angle ɑ is greater than 0 degrees and less than 90 degrees, wherein the first positioning portion includes at least two first positioning holes axially opened on the positioning body; the second positioning portion includes at least two second positioning holes opened between the first positioning holes, and the first positioning hole and the second positioning hole are used to pass through the first direction line and the second direction line respectively.

2. The hook according to claim 1, characterized in that: A line connecting the second positioning holes and a line connecting the first positioning holes have an angle β, and a value of the angle β is equal to a value of an angle between the first direction line and the second direction line.

3. The hook according to claim 2, characterized in that: There are two first positioning holes, and the two first positioning holes are respectively opened at two ends of the positioning body.

4. The hook according to claim 3, characterized in that: A bulging portion is formed on the positioning body corresponding to the first positioning hole and the second positioning hole.

5. The hook according to claim 2, characterized in that: A hook portion is provided beside each of the first positioning holes. The hook portion is formed by extending and bending the positioning body. The bending angles γ formed between each of the hook portions and the positioning body are the same.

6. The hook according to any one of claims 1 to 5, characterized in that: The projection of the hook portion on the positioning body is located on a first side or a second side of an axis of the positioning body, wherein the first side is an opposite side to the second side.

7. The hook according to claim 6, characterized in that: When the projection of the hook on the positioning body is located on the first side of the axis of the positioning body, the first positioning portion is used to limit the axial direction of the hook to the first direction line; when the projection of the hook on the positioning body is located on the second side of the axis of the positioning body, the first positioning portion is used to limit the axial direction of the hook to the second direction line.

8. An occluder, characterized in that: It is interwoven by the first direction line and the second direction line, and includes: a fixing plate, provided with a plurality of hooks as claimed in claim 6, for fixing in the left atrial appendage via the hooks; The occluding disk has a diameter larger than the fixing disk and is used for occluding the left atrial appendage.

9. The occluder according to claim 8, characterized in that: The hooks are respectively arranged on the first direction line and the second direction line of the fixing plate, and the hanging directions of the hooks are the same.

10. The occluder according to claim 8, characterized in that: The hooks are arranged in a wavy line along the circumference of the fixing plate.

Images