A gene chip data integration method, device and medium based on identification resolution

Abstract

This application discloses a gene chip data integration method, device and medium based on identification resolution, which is used to solve the technical problems that the data between existing platforms cannot be connected, the number of research repetitions is large, the number of test samples is small, and the credibility of the results is low. The method includes: determining the upstream and downstream equipment corresponding to the animal and plant gene fragments of the test sample; encoding the sample animal and plant gene fragments and upstream and downstream equipment based on identification resolution technology and identifying them through the DNA fragments of the gene chip; determining the existing research data corresponding to the DNA fragments, and registering the sample animal and plant gene fragments with identification, upstream and downstream equipment and existing research data to the secondary node of the identification resolution system; obtaining the existing research data of the gene chip from the secondary node according to the DNA fragments to perform digital twins and generate corresponding updated data, registering the updated data to the secondary node to realize the data integration of the gene chip, realize the interconnection and interoperability of data, reduce repetitive research, and improve the output rate of scientific research results.

Description

Technical Field

[0001] The present application relates to the field of gene chip technology, and in particular to a gene chip data integration method, device and medium based on identifier resolution. Background Art

[0002] Gene chips, also known as DNA microarrays, DNA chips, and biochips, utilize the principle of nucleic acid hybridization sequencing, i.e., determining nucleic acid sequences by hybridization with a set of nucleic acid probes of known sequence. Probes of known nucleotide sequences are immobilized on the surface of a substrate. High-density, addressable DNA molecular microarrays are created on the substrate surface. By complementing the labeled sample nucleic acid sequences, sequencing and massively parallel detection of information related to unknown biological genes are performed. Gene chip technology offers advantages such as high throughput, miniaturization, automation, rapidity, and accuracy. Gene chip technology is widely used in plant pathogen detection, stress resistance gene expression, transgenic detection, novel gene discovery, and mutant gene screening.

[0003] However, existing gene chip design costs are high. Basic experiments often require repeated research due to data inaccessibility between platforms, resulting in low data utilization efficiency and a low output rate of scientific research results. Furthermore, data is subject to high levels of uncontrollable factors. Due to the high cost of gene chips and the small number of test samples, experimental results lack credibility. Summary of the Invention

[0004] The embodiments of the present application provide a gene chip data integration method, device and medium based on identifier resolution, which are used to solve the technical problems of high design costs of existing gene chips, the inability to connect data between platforms in basic experiments, the high number of research repetitions, low data utilization efficiency, low output rate of scientific research results, high uncontrollable factors in the data, high cost of gene chips, small number of test samples, and lack of credibility of experimental results.

[0005] On the one hand, the embodiments of the present application provide a method for integrating gene chip data based on identifier resolution, comprising:

[0006] Obtaining sample animal and plant gene fragments corresponding to the gene chip, and determining upstream and downstream equipment corresponding to the gene chip detecting the sample animal and plant gene fragments;

[0007] Based on the identification resolution technology, the sample animal and plant gene fragments and the upstream and downstream devices are encoded, and the encoded sample animal and plant gene fragments and the upstream and downstream devices are identified through the DNA fragments of the gene chip;

[0008] Determine the existing research data corresponding to the DNA fragment of the gene chip, and register the sample animal and plant gene fragment with the identifier, the upstream and downstream equipment, and the existing research data to the secondary node in the identity resolution system;

[0009] According to the DNA fragment of the gene chip, the existing research data of the gene chip is obtained from the secondary node for digital twinning, and the updated data corresponding to the gene chip is generated, so that the updated data is registered to the secondary node to realize the data integration of the gene chip.

[0010] In one implementation of the present application, encoding the sample plant and animal gene fragments and the upstream and downstream devices based on the identification resolution technology specifically includes:

[0011] Determining the gene chip preparation equipment and gene chip reading equipment in the upstream and downstream equipment;

[0012] Based on the identification resolution technology and in accordance with the preset coding rules, the sample animal and plant gene fragments, the gene chip preparation equipment and the gene chip reading equipment are encoded to obtain the sample animal and plant gene fragments, the gene chip preparation equipment and the gene chip reading equipment in a unified coding form.

[0013] In one implementation of the present application, determining the existing research data corresponding to the DNA fragments of the gene chip specifically includes:

[0014] Determining existing research data corresponding to the DNA fragments of the gene chip; wherein the existing research data at least includes: relevant trait phenotypic information, signal pathway level information, protein expression level information, and metabolic pathway level information;

[0015] Classifying the existing research data according to the animal and plant species corresponding to the DNA fragments to obtain a plurality of sub-existing research data, and integrating the sub-existing research data of the same species;

[0016] The integrated sub-existing research data is marked by the DNA fragment.

[0017] In one implementation of the present application, after determining the existing research data corresponding to the DNA fragments of the gene chip, the method further includes:

[0018] Based on blockchain technology, a gene library corresponding to the gene chip is constructed, and the sample source, parent information, planting and collection data corresponding to the sample animal and plant gene fragments are encrypted according to the public key corresponding to the DNA fragment in the blockchain;

[0019] The existing research data, relevant literature and research results corresponding to the DNA fragment are stored in the corresponding DNA fragment in the gene library, so as to obtain the existing research data, relevant literature and research results based on the corresponding DNA fragment.

[0020] In one implementation of the present application, the method of obtaining the existing research data of the gene chip from the secondary node for digital twinning based on the DNA fragment of the gene chip and generating updated data corresponding to the gene chip specifically includes:

[0021] By scanning the identification code corresponding to the DNA fragment of the gene chip, the existing research data corresponding to the gene chip is obtained from the secondary node of the identification resolution system;

[0022] Based on the existing research data, a digital twin is generated through a digital twin experimental model, and a modification request is sent to the data integration entity of the gene chip;

[0023] The permission request information returned by the data integration subject is received, and based on the permission request information, update data corresponding to the gene chip is generated.

[0024] In one implementation of the present application, registering the updated data to the secondary node to achieve data integration of the gene chip specifically includes:

[0025] Comparing the updated data with the existing research data in the secondary node to determine data in the updated data that is identical to the existing research data in the secondary node;

[0026] Filtering duplicate values ​​of the data in the updated data that are identical to the existing research data, and converting the data format of the filtered updated data into a preset format;

[0027] The updated data in a preset format is registered to the secondary node to achieve data integration of the gene chip.

[0028] In one implementation of the present application, before obtaining the sample plant or animal gene fragment corresponding to the gene chip and determining the upstream and downstream devices corresponding to the sample plant or animal gene fragment detected by the gene chip, the method further includes:

[0029] Based on the Hadoop framework, all data corresponding to the gene chip are collected and analyzed using the Hive data analysis tool to determine the internal data corresponding to the internal system and the external data corresponding to the external server.

[0030] Based on the hybrid cloud architecture, a private cloud platform is constructed, and the internal data corresponding to the internal system is deployed on the private cloud platform, and the external data corresponding to the external server is deployed on the public cloud platform to realize data management of the gene chip.

[0031] In one implementation of the present application, after registering the updated data to the secondary node to achieve data integration of the gene chip, the method further includes:

[0032] Obtaining the identification code corresponding to the DNA fragment of the gene chip and the data after integration of the gene chip;

[0033] According to the identification code and the integrated data, a knowledge graph corresponding to the gene chip is constructed to display the data corresponding to the gene chip through the knowledge graph.

[0034] On the other hand, an embodiment of the present application further provides a gene chip data integration device based on identity resolution, the device comprising:

[0035] at least one processor;

[0036] and, a memory communicatively coupled to the at least one processor;

[0037] The memory stores instructions that can be executed by the at least one processor, and the instructions are executed by the at least one processor so that the at least one processor can execute the above-mentioned gene chip data integration method based on identifier resolution.

[0038] On the other hand, an embodiment of the present application further provides a non-volatile computer storage medium storing computer-executable instructions, wherein the computer-executable instructions are configured to:

[0039] Such as the above-mentioned gene chip data integration method based on identifier resolution.

[0040] The present invention provides a method, device, and medium for integrating gene chip data based on identifier resolution, which have at least the following beneficial effects:

[0041] By encoding the sample animal and plant gene fragments corresponding to the gene chip and the upstream and downstream equipment corresponding to the sample animal and plant gene fragments detected by the gene chip, and identifying the sample animal and plant gene fragments and upstream and downstream equipment through the NDA fragment of the gene chip, the coding identification corresponding to the sample animal and plant gene fragments and upstream and downstream equipment can be determined, and then data traceability can be performed based on the coding identification, thereby improving the utilization efficiency of the upstream and downstream equipment of the gene chip and facilitating the unified management of the equipment; determining the existing research data corresponding to the DNA fragment of the gene chip, and registering the existing research data, sample animal and plant gene fragments and upstream and downstream equipment to the secondary node in the identification resolution system, so that data interoperability can be achieved through the identification resolution system, providing data support for subsequent exploration of the relationship between gene expression; according to the DNA fragment of the gene chip, the existing research data is obtained from the secondary node for data twinning, and updated data corresponding to the gene chip is generated, which can reduce repetitive research and improve the standardization of the gene chip and the experimental repeatability; by registering the updated data to the secondary node, the data integration of the gene chip is realized, and the output rate of scientific research results is improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application. In the drawings:

[0043] Figure 1 A schematic diagram of a flow chart of a gene chip data integration method based on identifier resolution provided in an embodiment of the present application;

[0044] Figure 2 A schematic diagram of the internal structure of a gene chip data integration device based on identity resolution provided in an embodiment of the present application. DETAILED DESCRIPTION

[0045] To make the purpose, technical solutions, and advantages of this application more clear, the technical solutions of this application will be clearly and completely described below in conjunction with the specific embodiments of this application and the corresponding drawings. Obviously, the embodiments described are only part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0046] The embodiments of the present application provide a gene chip data integration method, device, and medium based on identity resolution, which encodes the sample animal and plant gene fragments corresponding to the gene chip and the upstream and downstream devices corresponding to the sample animal and plant gene fragments detected by the gene chip, and identifies the sample animal and plant gene fragments and upstream and downstream devices through the DNA fragments of the gene chip, thereby determining the coding identifiers corresponding to the sample animal and plant gene fragments and the upstream and downstream devices, and then tracing the data according to the coding identifiers, improving the utilization efficiency of the upstream and downstream devices of the gene chip, and facilitating the unified management of the upstream and downstream devices; determining the existing research data corresponding to the DNA fragments of the gene chip, and registering the existing research data, sample animal and plant gene fragments, and upstream and downstream devices to the secondary node in the identity resolution system, which can realize data interconnection and interoperability through the identity resolution system, and provide data support for subsequent exploration of the relationship between gene expression; according to the DNA fragments of the gene chip, obtaining the existing research data from the secondary node for data twinning, and generating updated data corresponding to the gene chip, which can reduce repetitive research and improve the standardization of the gene chip and the experimental repeatability; by registering the updated data to the secondary node, the data integration of the gene chip is realized, and the output rate of scientific research results is improved. It solves the technical problems of high design costs of existing gene chips, the inability to connect data between platforms in basic experiments, the high number of research repetitions, low data utilization efficiency, low output rate of scientific research results, high uncontrollable factors in the data, high cost of gene chips, small number of test samples, and lack of credibility of experimental results.

[0047] Figure 1 The following is a flow chart of a gene chip data integration method based on identifier resolution provided in the embodiment of the present application. Figure 1 As shown, a gene chip data integration method based on identifier resolution provided in an embodiment of the present application may mainly include the following steps:

[0048] Step 101: Obtain the sample plant and animal gene fragments corresponding to the gene chip, and determine the upstream and downstream devices corresponding to the gene chip detection of the sample plant and animal gene fragments.

[0049] Because gene UTR regions share common promoters, genes with similar expression profiles may share common regulatory elements and be regulated by the same upstream factors. A gene transcription regulatory network is a directed network with transcription factors and regulated genes as nodes and regulatory relationships as edges. Currently, gene and pathway databases are not integrated with gene chip design and subsequent data analysis. Data interoperability is not achieved in data acquisition, transmission, calculation, and analysis, and the authenticity and security of the data cannot be guaranteed.

[0050] In order to solve the above problems, this application uses the DNA fragments corresponding to different traits in the gene chip as unique identity identifiers. The server obtains the sample animal and plant gene fragments corresponding to the gene chip, and based on the sample animal and plant fragments, determines the corresponding upstream and downstream devices when the gene chip detects the sample animal and plant fragments, so that the sample animal and plant fragments and upstream and downstream devices related to the gene chip can be obtained.

[0051] In one embodiment of the present application, before obtaining the sample plant or animal gene fragments corresponding to the gene chip and determining the upstream and downstream devices corresponding to the gene chip detection sample plant or animal gene fragments, the server uses the Hadoop technology framework to collect all data corresponding to the gene chip, and uses the Hive data analysis tool to perform data analysis on all the collected data corresponding to the gene chip, thereby determining the internal data corresponding to the internal system and the external data corresponding to the external server. Then, a hybrid cloud architecture is used to deploy all the data corresponding to the gene chip. The server builds a private cloud platform, deploys the internal data belonging to the internal system on the private cloud platform, and deploys the external data belonging to the external server on the public cloud platform, thereby realizing data management of the gene chip.

[0052] Step 102: Based on the identification resolution technology, the sample animal and plant gene fragments and upstream and downstream devices are encoded, and the encoded sample animal and plant gene fragments and upstream and downstream devices are identified through the DNA fragments of the gene chip.

[0053] The identification resolution system helps break down data silos and supports the use of private identifiers between enterprises and research institutes within a unified ecosystem. The Industrial Internet identification resolution system can establish unified public identifiers across all sectors, industries, and value chains. It supports compatibility with mainstream international identification systems and provides a public query portal and standardized query services to support the exchange and sharing of identification data within the system.

[0054] By replacing private identifiers with public identifiers, identification resolution can effectively connect data silos across various links, between enterprises, and between research institutions, fully enhancing the integration of "production," "learning," and "research," effectively breaking down information transmission barriers and improving R&D and innovation efficiency. During R&D and production, by scanning identification codes, data from the entire upstream and downstream chain of gene chips, including design and development, experimental material sources, related field research, testing instruments, analysis platform data, and regulatory platforms, can be automatically obtained, enabling more efficient, flexible, intelligent, and accurate parameter configuration, instrument and equipment control, and problem analysis.

[0055] Based on identification resolution technology, the server encodes the obtained sample animal and plant gene fragments and the determined upstream and downstream devices, and identifies the encoded sample animal and plant gene fragments and upstream and downstream devices through DNA fragments of different characteristics in the gene chip, so as to determine the identification codes of the sample animal and plant gene fragments and upstream and downstream devices, so as to facilitate the subsequent finding of the sample animal and plant gene fragments and upstream and downstream devices corresponding to the DNA fragments of the gene chip according to the determined identification codes.

[0056] Specifically, the server determines the gene chip preparation equipment and gene chip reading equipment in the upstream and downstream devices of the encoded gene chip, and based on the identification resolution technology, encodes the sample animal and plant gene fragments, gene chip preparation equipment and gene chip reading equipment corresponding to the gene chip according to the preset coding rules, so as to obtain sample animal and plant gene fragments, gene chip preparation equipment and gene chip reading equipment with a unified coding form.

[0057] Step 103: Determine the existing research data corresponding to the DNA fragment of the gene chip, and register the sample animal and plant gene fragments with identification, upstream and downstream equipment and existing research data to the secondary node in the identification resolution system.

[0058] The server determines the existing research data corresponding to the DNA fragments of the gene chip, and then registers the identified sample animal and plant gene fragments, upstream and downstream equipment, and existing research data to the secondary node in the identification resolution system. The identification resolution system is used to achieve interconnection and interoperability of gene chip-related data, providing data support for subsequent exploration of the relationship between gene expression, reducing repetitive research, and improving the output rate of scientific research results.

[0059] Specifically, the server determines the existing research data corresponding to the DNA fragment of the gene chip. It should be noted that the existing research data in the embodiment of the present application at least includes: relevant trait phenotypic information, signal pathway level information, protein expression level information and metabolic pathway level information.

[0060] For example, the gene chip technology used in screening plant pathogens, studying specific stress genes, and detecting genetically modified agricultural products can utilize the unique identity of specific DNA fragments. Based on this technology, the genetic data involved in the research are first analyzed, and the feasibility of the gene chip design is simulated by digital twins to reduce R&D costs.

[0061] The server then classifies the existing research data according to the animal and plant species corresponding to the DNA fragments, so as to obtain multiple sub-existing research data, and integrate the sub-existing research data of the same type, and identify the integrated sub-existing research data through DNA fragments, so that the entire detection process is standardized and proceduralized, and the entire chain of data can be traced.

[0062] In one embodiment of the present application, after determining the existing research data corresponding to the DNA fragment of the gene chip, the server constructs a gene library corresponding to the gene chip based on blockchain technology, and encrypts the sample source, parent information, planting and collection data corresponding to the sample animal and plant gene fragment according to the public key corresponding to the DNA fragment in the blockchain, and then stores the existing research data, relevant literature and research results corresponding to the DNA fragment in the gene library to the corresponding DNA fragment, so as to facilitate the subsequent acquisition of existing research data, relevant literature and research results according to the DNA fragment corresponding to the gene chip, reduce repetitive research, and improve the output rate of scientific research results.

[0063] Step 104: Based on the DNA fragment of the gene chip, obtain the existing research data of the gene chip from the secondary node for digital twinning, and generate updated data corresponding to the gene chip to register the updated data to the secondary node to realize data integration of the gene chip.

[0064] The server scans the DNA fragments of the gene chip, obtains the existing research data of the gene chip from the secondary node of the identification resolution system and performs digital twinning, so as to generate updated data corresponding to the gene chip, and then registers the updated data to the secondary node to realize the data integration of the gene chip.

[0065] Specifically, the server scans the identification code corresponding to the DNA fragment of the gene chip, obtains the existing research data corresponding to the gene chip from the secondary node of the identification resolution system, and then performs digital twinning through the digital twin experimental model based on the existing research data, and sends a modification request to the data integration entity of the gene chip. When receiving the permission request information returned by the data integration entity, the server generates the updated data corresponding to the gene chip based on the permission request information.

[0066] The server compares the updated data with the existing research data in the secondary node, and can determine the data in the updated data that is identical to the existing research data in the secondary node, and then filters out the duplicate values ​​of the data in the updated data that is identical to the existing research data, converts the data format of the filtered updated data into a preset format, and then registers the updated data in the preset format to the secondary node, thereby realizing data integration of the gene chip.

[0067] In one embodiment of the present application, after registering the updated data to the secondary node and realizing the data integration of the gene chip, the server obtains the identification code corresponding to the DNA fragment of the gene chip and the data after the integration of the gene chip, and then constructs the knowledge graph corresponding to the gene chip based on the identification code and the integrated data, so that the data corresponding to the gene chip can be displayed through the knowledge graph.

[0068] The above is an embodiment of the method proposed in this application. Based on the same inventive concept, this application embodiment also provides a gene chip data integration device based on identity resolution, the structure of which is as follows: Figure 2 shown.

[0069] Figure 2 This is a schematic diagram of the internal structure of a gene chip data integration device based on identity resolution provided in an embodiment of the present application. Figure 2 As shown, the equipment includes:

[0070] at least one processor;

[0071] and, a memory communicatively coupled to the at least one processor;

[0072] The memory stores instructions that can be executed by at least one processor, and the instructions are executed by the at least one processor to enable the at least one processor to:

[0073] Obtain the sample animal and plant gene fragments corresponding to the gene chip, and determine the upstream and downstream equipment corresponding to the gene chip detection sample animal and plant gene fragments;

[0074] Based on the identification resolution technology, the sample animal and plant gene fragments and upstream and downstream equipment are encoded, and the encoded sample animal and plant gene fragments and upstream and downstream equipment are identified through the DNA fragments of the gene chip;

[0075] Determine the existing research data corresponding to the DNA fragments of the gene chip, and register the identified sample animal and plant gene fragments, upstream and downstream equipment, and existing research data to the secondary node in the identification resolution system;

[0076] According to the DNA fragments of the gene chip, the existing research data of the gene chip is obtained from the secondary node for digital twinning, and the updated data corresponding to the gene chip is generated to register the updated data to the secondary node to realize the data integration of the gene chip.

[0077] The embodiment of the present application further provides a non-volatile computer storage medium storing computer-executable instructions, wherein the computer-executable instructions are configured as follows:

[0078] Obtain the sample animal and plant gene fragments corresponding to the gene chip, and determine the upstream and downstream equipment corresponding to the gene chip detection sample animal and plant gene fragments;

[0079] Based on the identification resolution technology, the sample animal and plant gene fragments and upstream and downstream equipment are encoded, and the encoded sample animal and plant gene fragments and upstream and downstream equipment are identified through the DNA fragments of the gene chip;

[0080] Determine the existing research data corresponding to the DNA fragments of the gene chip, and register the identified sample animal and plant gene fragments, upstream and downstream equipment, and existing research data to the secondary node in the identification resolution system;

[0081] According to the DNA fragments of the gene chip, the existing research data of the gene chip is obtained from the secondary node for digital twinning, and the updated data corresponding to the gene chip is generated to register the updated data to the secondary node to realize the data integration of the gene chip.

[0082] The various embodiments in this application are described in a progressive manner. Similar portions between the various embodiments can be referred to in conjunction with each other. Each embodiment focuses on the differences between the other embodiments. In particular, the device and medium embodiments are generally similar to the method embodiments, so their descriptions are relatively simple. For relevant portions, refer to the descriptions of the method embodiments.

[0083] The devices and media provided in the embodiments of the present application correspond one-to-one to the methods. Therefore, the devices and media also have similar beneficial technical effects to their corresponding methods. Since the beneficial technical effects of the methods have been described in detail above, the beneficial technical effects of the devices and media will not be repeated here.

[0084] Those skilled in the art will appreciate that the embodiments of the present application can be provided as methods, systems, or computer program products. Therefore, the present application can adopt the form of a complete hardware embodiment, a complete software embodiment, or an embodiment in combination with software and hardware. Moreover, the present application can adopt the form of a computer program product implemented on one or more computer-usable storage media (including but not limited to magnetic disk storage, CD-ROM, optical storage, etc.) that contain computer-usable program code.

[0085] The present application is described with reference to the flowcharts and / or block diagrams of the methods, devices (systems), and computer program products according to the embodiments of the present application. It should be understood that each process and / or box in the flowchart and / or block diagram, as well as the combination of the processes and / or boxes in the flowchart and / or block diagram, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, a special-purpose computer, an embedded processor, or other programmable data processing device to produce a machine, so that the instructions executed by the processor of the computer or other programmable data processing device generate instructions for implementing the steps in the process. Figure 1 a process or multiple processes and / or boxes Figure 1 A device that provides the functions specified in a block or multiple blocks.

[0086] These computer program instructions may also be stored in a computer readable memory that can direct a computer or other programmable data processing device to work in a specific manner, so that the instructions stored in the computer readable memory produce an article of manufacture comprising an instruction device, which implements the process Figure 1 a process or multiple processes and / or boxes Figure 1 The function specified in one or more boxes.

[0087] These computer program instructions can also be loaded onto a computer or other programmable data processing device so that a series of operational steps are executed on the computer or other programmable device to produce a computer-implemented process, thereby providing the instructions executed on the computer or other programmable device for implementing the process. Figure 1 a process or multiple processes and / or boxes Figure 1 A step that specifies a function in one or more boxes.

[0088] In a typical configuration, a computing device includes one or more processors (CPUs), input / output interfaces, network interfaces, and memory.

[0089] Memory may include non-permanent storage in a computer-readable medium, random access memory (RAM) and / or non-volatile memory in the form of read-only memory (ROM) or flash RAM. Memory is an example of a computer-readable medium.

[0090] Computer-readable media includes permanent and non-permanent, removable and non-removable media that can be implemented by any method or technology to store information. The information can be computer-readable instructions, data structures, program modules or other data. Examples of computer storage media include, but are not limited to, phase change memory (PRAM), static random access memory (SRAM), dynamic random access memory (DRAM), other types of random access memory (RAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), flash memory or other memory technology, compact disc read-only memory (CD-ROM), digital versatile disc (DVD) or other optical storage, magnetic cassettes, magnetic tape, magnetic disk storage or other magnetic storage devices or any other non-transmission media that can be used to store information that can be accessed by a computing device. As defined herein, computer-readable media does not include transitory computer-readable media (transitory media), such as modulated data signals and carrier waves.

[0091] It should also be noted that the terms "comprises," "includes," or any other variations thereof are intended to encompass non-exclusive inclusion, such that a process, method, commodity, or apparatus that includes a series of elements includes not only those elements but also other elements not explicitly listed, or includes elements inherent to such process, method, commodity, or apparatus. In the absence of further limitations, an element defined by the phrase "comprises a ..." does not exclude the presence of other identical elements in the process, method, commodity, or apparatus that includes the element.

[0092] The foregoing is merely an embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various changes and variations. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present application should all be included within the scope of the claims of the present application.

Claims

1. A gene chip data integration method based on identifier resolution, characterized in that: The method comprises: Obtaining sample animal and plant gene fragments corresponding to the gene chip, and determining upstream and downstream equipment corresponding to the gene chip detecting the sample animal and plant gene fragments; Based on the identification resolution technology, the sample animal and plant gene fragments and the upstream and downstream devices are encoded, and the encoded sample animal and plant gene fragments and the upstream and downstream devices are identified through the DNA fragments of the gene chip; Determine the existing research data corresponding to the DNA fragment of the gene chip, and register the sample animal and plant gene fragment with the identifier, the upstream and downstream equipment, and the existing research data to the secondary node in the identity resolution system; According to the DNA fragment of the gene chip, the existing research data of the gene chip is obtained from the secondary node for digital twinning, and the updated data corresponding to the gene chip is generated, so as to register the updated data to the secondary node to realize the data integration of the gene chip; The method of obtaining the existing research data of the gene chip from the secondary node based on the DNA fragment of the gene chip for digital twinning and generating updated data corresponding to the gene chip specifically includes: By scanning the identification code corresponding to the DNA fragment of the gene chip, the existing research data corresponding to the gene chip is obtained from the secondary node of the identification resolution system; Based on the existing research data, a digital twin is generated through a digital twin experimental model, and a modification request is sent to the data integration entity of the gene chip; The permission request information returned by the data integration subject is received, and based on the permission request information, update data corresponding to the gene chip is generated.

2. A gene chip data integration method based on identity resolution according to claim 1, characterized in that: The encoding of the sample plant and animal gene fragments and the upstream and downstream devices based on the identification resolution technology specifically includes: Determining the gene chip preparation equipment and gene chip reading equipment in the upstream and downstream equipment; Based on the identification resolution technology and in accordance with the preset coding rules, the sample animal and plant gene fragments, the gene chip preparation equipment and the gene chip reading equipment are encoded to obtain the sample animal and plant gene fragments, the gene chip preparation equipment and the gene chip reading equipment in a unified coding form.

3. The method for integrating gene chip data based on identity resolution according to claim 1, characterized in that: The determination of the existing research data corresponding to the DNA fragments of the gene chip specifically includes: Determining existing research data corresponding to the DNA fragments of the gene chip; wherein the existing research data at least includes: relevant trait phenotypic information, signal pathway level information, protein expression level information, and metabolic pathway level information; Classifying the existing research data according to the animal and plant species corresponding to the DNA fragments to obtain a plurality of sub-existing research data, and integrating the sub-existing research data of the same species; The integrated sub-existing research data is marked by the DNA fragment.

4. The method for integrating gene chip data based on identity resolution according to claim 1, characterized in that: After determining the existing research data corresponding to the DNA fragments of the gene chip, the method further includes: Based on blockchain technology, a gene library corresponding to the gene chip is constructed, and the sample source, parent information, planting and collection data corresponding to the sample animal and plant gene fragments are encrypted according to the public key corresponding to the DNA fragment in the blockchain; The existing research data, relevant literature and research results corresponding to the DNA fragment are stored in the corresponding DNA fragment in the gene library, so as to obtain the existing research data, relevant literature and research results based on the corresponding DNA fragment.

5. The method for integrating gene chip data based on identity resolution according to claim 1, characterized in that: Registering the updated data to the secondary node to achieve data integration of the gene chip specifically includes: Comparing the updated data with the existing research data in the secondary node to determine data in the updated data that is identical to the existing research data in the secondary node; Filtering duplicate values ​​of the data in the updated data that are identical to the existing research data, and converting the data format of the filtered updated data into a preset format; The updated data in a preset format is registered to the secondary node to achieve data integration of the gene chip.

6. The method for integrating gene chip data based on identity resolution according to claim 1, characterized in that: Before obtaining the sample plant and animal gene fragments corresponding to the gene chip and determining the upstream and downstream devices corresponding to the sample plant and animal gene fragments detected by the gene chip, the method further includes: Based on the Hadoop framework, all data corresponding to the gene chip are collected and analyzed using the Hive data analysis tool to determine the internal data corresponding to the internal system and the external data corresponding to the external server. Based on the hybrid cloud architecture, a private cloud platform is constructed, and the internal data corresponding to the internal system is deployed on the private cloud platform, and the external data corresponding to the external server is deployed on the public cloud platform to realize data management of the gene chip.

7. The method for integrating gene chip data based on identity resolution according to claim 1, characterized in that: After registering the updated data to the secondary node to achieve data integration of the gene chip, the method further includes: Obtaining the identification code corresponding to the DNA fragment of the gene chip and the data after integration of the gene chip; According to the identification code and the integrated data, a knowledge graph corresponding to the gene chip is constructed to display the data corresponding to the gene chip through the knowledge graph.

8. A gene chip data integration device based on identity resolution, characterized in that: The device comprises: at least one processor; and, a memory communicatively coupled to the at least one processor; The memory stores instructions that can be executed by the at least one processor, and the instructions are executed by the at least one processor so that the at least one processor can execute the gene chip data integration method based on identifier resolution as described in any one of claims 1 to 7.

9. A non-volatile computer storage medium storing computer executable instructions, characterized in that: The computer executable instructions are configured to: A gene chip data integration method based on identifier resolution as described in any one of claims 1 to 7.

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