Control method of gas supply system and gas supply system
By obtaining the gas concentration in the biological incubator, calculating the difference value and switching the gas supply cylinder according to the preset value and time conditions, the problem of untimely switching of gas concentration in the prior art is solved, and efficient utilization of gas and healthy growth of cells and tissues is achieved.
Patent Information
- Application Number
- CN202210749014.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-06-28
- Publication Date
- 2025-06-06
- Estimated Expiration
- 2042-06-28
AI Technical Summary
The existing biological incubator cannot switch the main gas supply cylinder and the spare gas supply cylinder in time according to the gas concentration in the biological incubator, resulting in gas waste or affecting the growth of cells and tissues.
By obtaining the gas concentration in the incubator, the difference between the standard concentration is calculated, and switching according to the preset value and time conditions, selectively switching to a backup gas supply cylinder for gas supply.
It realizes timely switching gas supply cylinders according to the gas concentration to avoid gas waste, ensure the stable gas concentration in the incubator, and promote the normal growth of cells and tissues.
Smart Images

Figure CN115248606B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of biological culture equipment, and specifically provides a control method of an air supply system and an air supply system. Background Art
[0002] The biological incubator is a device that simulates the formation of a cell or tissue-like structure in the incubator for in vitro culture.
[0003] Take the CO2 incubator as an example. The CO2 incubator can provide the appropriate temperature and CO2 concentration required for the growth of cells and tissues. The CO2 gas is provided by an external gas cylinder, which generally includes a main gas supply cylinder and a backup gas supply cylinder. When the CO2 in the main gas supply cylinder is exhausted, it is necessary to switch to the backup gas supply cylinder to supply gas to the CO2 incubator.
[0004] The existing biological incubator cannot switch the main gas supply cylinder and the backup gas supply cylinder in time according to the gas concentration in the biological incubator, thereby causing waste of gas in the cylinder or affecting the growth of cells and tissues in the incubator.
[0005] Therefore, this field needs a new technical solution to solve the above problems. Summary of the invention
[0006] The present invention aims to solve the above technical problem, that is, to solve the problem that the existing biological incubator cannot switch the main gas supply cylinder and the backup gas supply cylinder in time according to the gas concentration in the biological incubator.
[0007] In a first aspect, the present invention provides a control method for a gas supply system, the gas supply system comprising an incubator, a main gas supply cylinder and a spare gas supply cylinder, the control method comprising: obtaining a gas concentration C in the incubator; 1 According to the gas concentration C 1 and standard concentration C 0 , selectively switching to the backup gas supply cylinder to supply gas to the incubator.
[0008] In the preferred technical solution of the above control method, "according to the gas concentration C 1 and standard concentration C 0 , selectively switching to the standby gas supply cylinder to supply gas to the incubator” includes: calculating the first difference △ 1 =C 0 -C 1 ; The first difference △ 1 With the first preset value A 1 performing a comparison; and selectively switching to the backup gas supply cylinder to supply gas to the incubator based on the comparison result.
[0009] In the preferred technical solution of the above control method, the specific steps of "selectively switching to supplying gas to the incubator from the backup gas supply cylinder according to the comparison result" include: if △ 1 ≤A 1 , then the incubator is not switched to be supplied with gas from the backup gas cylinder; if △ 1 >A 1 The duration reaches the first preset time T 1 , then further determine that at the second preset time T 2 Whether the gas concentration in the incubator increases within the time limit; and according to the judgment result, selectively switching to the backup gas supply cylinder to supply gas to the incubator.
[0010] In the preferred technical solution of the above control method, the specific step of "selectively switching to the backup gas supply cylinder to supply gas to the incubator according to the judgment result" includes: if the judgment result is "yes", not switching to the backup gas supply cylinder to supply gas to the incubator; if the judgment result is "no", increasing the gas supply volume of the main gas supply cylinder, and further judging whether the backup gas supply cylinder is switched to the backup gas supply cylinder within the third preset time T. 3 Whether the gas concentration in the incubator increases within the time limit; and according to the judgment result, selectively switching to the backup gas supply cylinder to supply gas to the incubator.
[0011] In the preferred technical scheme of the above-mentioned control method, the specific step of "selectively switching to the backup gas supply cylinder to supply gas to the incubator according to the judgment result" includes: if the judgment result is "yes", then do not switch to the backup gas supply cylinder to supply gas to the incubator; if the judgment result is "no", then switch to the backup gas supply cylinder to supply gas to the incubator.
[0012] In a preferred technical solution of the above control method, the gas supply system further includes an alarm device, and when the judgment result is "no", the control method further includes: activating the alarm device.
[0013] In the preferred technical solution of the above control method, the specific step of "increasing the gas supply of the main gas supply cylinder" includes: adjusting the valve opening of the main gas supply cylinder to the maximum opening.
[0014] In the preferred technical solution of the above control method, the control method of the present invention further comprises: if △ 1 >A 1 The duration reaches the fourth preset time T 4 When the incubator is switched to be supplied with gas by the standby gas supply cylinder.
[0015] In the preferred technical solution of the above control method, “determining that at the second preset time T 2 The specific steps of "whether the gas concentration in the incubator increases within the range of 1 to 2000" include: calculating the second difference △ 2 =C i+n -C i ; The second difference △ 2 With the second preset value A 2 Compare; if △ 2 >A 2 , it is determined that within the second preset time T 2 The gas concentration in the incubator increases within ; wherein, C i is the gas concentration in the incubator obtained at the beginning of the judgment, C i+n It is the gas concentration in the incubator obtained every n set time periods after the judgment starts.
[0016] In a second aspect, the present invention provides an air supply system. The air supply system of the present invention includes a controller, and the controller is configured to be able to execute the control method described above.
[0017] When the above technical scheme is adopted, the gas supply system of the present invention can selectively switch to the backup gas supply cylinder for gas supply to the incubator according to the gas concentration and the standard concentration, so that the present invention can timely switch the gas supply from the main gas supply cylinder to the backup gas supply cylinder according to the gas concentration and the standard concentration in the incubator. On the one hand, it can prevent the main gas supply cylinder from switching untimely and causing the gas supply system to supply gas to the incubator intermittently, thereby affecting the growth of cells and tissues in the incubator; on the other hand, it can prevent the waste of residual gas in the main gas supply cylinder due to premature switching of the main gas supply cylinder. At the same time, compared with setting a pressure sensor in the cylinder and switching the gas supply from the main gas supply cylinder to the backup gas supply cylinder according to the value of the pressure sensor, it can save the use of pressure sensors, thereby reducing the cost of the gas supply system.
[0018] Furthermore, by first calculating the difference between the gas concentration in the incubator and the standard concentration, and then comparing the difference with the first preset value, compared with directly comparing the gas concentration with the standard concentration, it is possible to avoid misjudgment of the gas concentration in the incubator due to detection errors in the gas concentration in the incubator, thereby making the judgment of switching between the main gas supply cylinder and the backup gas supply cylinder more accurate.
[0019] Furthermore, by taking the first difference △ 1 With the first preset value A 1 For comparison, selectively switch to the backup gas cylinder to supply gas to the incubator. On the one hand, when △ 1 ≤A1 When △ , the incubator is not switched to the backup gas supply cylinder for gas supply, which indicates that the difference between the gas concentration in the incubator and the standard concentration is small, that is, the main gas supply cylinder can provide gas to the incubator so that the concentration in the incubator provides a suitable concentration of gas for the growth of cells and tissues in the incubator. At this time, there is no need to switch the gas supply cylinder; on the other hand, when △ 1 >A 1 The duration reaches the first preset time T 1 , further determine at the second preset time T 2 Whether the gas concentration in the incubator increases within 2 hours, and when △ 1 >A 1 Then, it is further determined that at the second preset time T 2 By monitoring whether the gas concentration in the incubator is lower than the standard concentration for a period of time exceeding the first preset time T 1 Then further determine at the second preset time T 2 Whether the gas concentration in the incubator increases within a certain period of time can avoid the error of gas concentration detection causing △ 1 >A 1 The misjudgment caused by △ 1 >A 1 The duration reaches the first preset time T 1 , indicating that the gas concentration in the incubator is lower than the standard concentration for a period of time. At this time, it may be that the gas volume in the main gas supply cylinder is insufficient, or there is no gas in the main gas supply cylinder. Therefore, it is necessary to further judge the gas concentration in the second preset time T 2 The gas concentration in the incubator increases within a certain period of time to determine whether the main gas supply cylinder is still supplying gas to the incubator.
[0020] Furthermore, by determining at the second preset time T 2 Whether the gas concentration in the incubator increases within the second preset time T 2 If the gas concentration in the incubator increases within the second preset time T, it means that the main gas supply cylinder is still supplying gas to the incubator, that is, there is still residual gas in the main gas supply cylinder. Therefore, the incubator is not switched to the backup gas supply cylinder to supply gas to the incubator, so as to avoid wasting the residual gas in the main gas supply cylinder. On the other hand, if the gas concentration in the incubator increases within the second preset time T, it means that the main gas supply cylinder is still supplying gas to the incubator, that is, there is still residual gas in the main gas supply cylinder. 2 If the gas concentration in the incubator does not increase within the second preset time T, it may be that the main gas cylinder has run out of gas. Alternatively, it may be that there is still gas in the main gas cylinder, but the gas intake is slow due to insufficient gas volume, resulting in the second preset time T. 2The gas concentration in the incubator does not increase within the third preset time T. Therefore, it is necessary to further increase the gas supply of the main gas supply cylinder and detect 3 By determining whether the gas concentration in the incubator increases within a certain period of time, it is determined whether the main gas supply cylinder can supply gas to the incubator, and further whether there is any residual gas in the main gas supply cylinder, thereby avoiding the waste of the residual gas in the main gas supply cylinder.
[0021] Furthermore, based on the judgment result of whether the gas concentration in the incubator increases within the third preset time, the method selectively switches to the backup gas supply cylinder for gas supply to the incubator. On the one hand, if the gas concentration in the incubator increases within the third preset time after the gas supply of the main gas supply cylinder is increased, it means that although the gas volume in the main gas supply cylinder is insufficient, there is still residual gas. At this time, the method does not switch to the backup gas supply cylinder for gas supply to the incubator to avoid wasting the residual gas in the main gas supply cylinder. On the other hand, if the gas concentration in the incubator still does not increase within the third preset time after the gas supply of the main gas supply cylinder is increased, it means that there is no gas in the main gas supply cylinder. At this time, it is necessary to switch to the backup gas supply cylinder for gas supply to the incubator to avoid affecting the growth of cells and tissues in the incubator due to insufficient gas supply in the incubator.
[0022] Furthermore, when △ 1 >A 1 The duration reaches the fourth preset time T 4 When △ 1 >A 1 The duration reaches the fourth preset time T 4 It means that the gas concentration in the incubator has been lower than the standard concentration for too long. At this time, timely switching to the spare gas supply cylinder to supply gas to the incubator can avoid the normal growth of cells and tissues in the incubator being affected by the gas concentration in the incubator being lower than the standard concentration for a long time.
[0023] In addition, the gas supply system further provided by the present invention on the basis of the above-mentioned technical solution adopts the control method introduced above, and thus has the beneficial effects of the above-mentioned control method. Compared with the gas supply system before the improvement, the gas supply system of the present invention is more accurate in judging when switching between the main gas supply cylinder and the backup gas supply cylinder, and the switching is more timely, thereby avoiding gas waste while ensuring that the normal growth of cells and tissues in the incubator is not affected. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings, in which:
[0025] Figure 1It is a structural schematic diagram of the gas supply system of the present invention;
[0026] Figure 2 is a flow chart of the control method of the present invention;
[0027] Figure 3 is a flow chart of an embodiment of a control method of the present invention.
[0028] List of reference numerals:
[0029] 1. Incubator; 11. Gas concentration sensor; 12. Alarm device; 2. Main gas supply cylinder; 21. First pipeline; 211. First control valve; 3. Backup gas supply cylinder; 31. Second pipeline; 311. Second control valve. DETAILED DESCRIPTION
[0030] The preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only used to explain the technical principles of the present invention and are not intended to limit the protection scope of the present invention.
[0031] It should be noted that in the description of the present invention, the term "inside" is based on the direction or position relationship shown in the drawings, which is only for the convenience of description, and does not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first", "second", "third", and "fourth" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.
[0032] In addition, it should be noted that in the description of the present invention, unless otherwise clearly specified and limited, the terms "disposed" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0033] Based on the problem pointed out in the background technology that the existing biological incubator cannot timely switch the main gas supply cylinder and the backup gas supply cylinder according to the gas concentration in the biological incubator. The present invention provides a control method for a gas supply system, aiming to enable the gas supply system of the present invention to switch to the backup gas supply cylinder to supply gas to the incubator in time according to the gas concentration in the incubator.
[0034] See also Figure 1 , Figure 1 It is a structural schematic diagram of the gas supply system of the present invention.
[0035] like Figure 1As shown, the gas supply system of the present invention includes an incubator 1, a main gas supply cylinder 2 and a backup gas supply cylinder 3. Both the main gas supply cylinder 2 and the backup gas supply cylinder 3 can supply gas to the incubator 1. Under normal circumstances, the incubator 1 is supplied with gas through the main gas supply cylinder 2. When the gas in the main gas supply cylinder 2 is insufficient, it automatically switches to the backup gas supply cylinder 3 for gas supply.
[0036] Exemplarily, the main gas supply cylinder 2 and the backup gas supply cylinder 3 both store carbon dioxide gas, and the main gas supply cylinder 2 and the backup gas supply cylinder 3 are connected to the incubator 1 through the first pipeline 21 and the second pipeline 31, respectively. The first control valve 211 and the second control valve 311 are respectively provided on the first pipeline 21 and the second pipeline 31, and the switching between the main gas supply cylinder 2 and the backup gas supply cylinder 3 is realized by controlling the opening and closing of the first control valve 211 and the second control valve 311.
[0037] It should be noted that in actual application, it is not limited to the above-mentioned main gas supply cylinder 2 and spare gas supply cylinder 3 being connected to the incubator 1 through the first pipeline 21 and the second pipeline 31 respectively, and the switching between the main gas supply cylinder 2 and the spare gas supply cylinder 3 is achieved by controlling the first control valve 211 and the second control valve 311 provided on the first pipeline 21 and the second pipeline 31. For example, the gas supply ports of the main gas supply cylinder 2 and the spare gas supply cylinder 3 can also be directly connected to the incubator 1, and the switching between the main gas supply cylinder 2 and the spare gas supply cylinder 3 can be achieved by controlling the control valves on the main gas supply cylinder 2 and the spare gas supply cylinder 3, etc. Such flexible adjustment and change do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention. Of course, preferably, the switching between the main gas supply cylinder 2 and the spare gas supply cylinder 3 is achieved by controlling the first control valve 211 and the second control valve 311 provided on the first pipeline 21 and the second pipeline 31.
[0038] It should also be noted that, in actual applications, those skilled in the art may set both the first control valve 211 and the second control valve 311 as manual valves, or both the first control valve 211 and the second control valve 311 as electrically-controlled valves, or one of the first control valve 211 and the second control valve 311 may be set as a manual valve and the other of the first control valve 211 and the second control valve 311 may be set as an electrically-controlled valve, and so on. Such adjustments and changes to the specific setting types of the first control valve 211 and the second control valve 311 do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0039] Preferably, the first control valve 211 and the second control valve 311 are both configured as electrically controlled valves.
[0040] The following describes a specific embodiment of the present invention by taking the example that the main gas supply cylinder 2 supplies gas to the incubator 1 (ie, the first control valve 211 is open) and the spare gas supply cylinder 3 is used as a spare (the second control valve 311 is closed).
[0041] Continue reading Figure 2 , Figure 2 is a flow chart of the control method of the present invention.
[0042] like Figure 2 As shown, the control method of the present invention comprises the following steps:
[0043] S100: Obtain the gas concentration C in incubator 1 1 ;
[0044] S200: According to gas concentration C 1 and standard concentration C 0 , selectively switch to the backup gas supply cylinder 3 to supply gas to the incubator 1.
[0045] Through such an arrangement, the gas supply from the main gas supply cylinder 2 to the incubator 1 can be switched to the backup gas supply cylinder 3 in time according to the gas concentration and the standard concentration in the incubator 1. On the one hand, it can prevent the main gas supply cylinder 2 from being switched untimely, causing the gas supply system to interrupt the gas supply to the incubator 1, thereby affecting the growth of cells and tissues in the incubator 1; on the other hand, it can prevent the waste of the main gas supply cylinder 2 due to the premature switching of the main gas supply cylinder 2. At the same time, compared with the method of setting a pressure sensor in the main gas supply cylinder 2 and switching the gas supply from the main gas supply cylinder 2 to the backup gas supply cylinder 3 according to the value of the pressure sensor, it can save the use of pressure sensors, thereby reducing the cost of the gas supply system.
[0046] It should also be noted that, in actual applications, those skilled in the art can switch the gas supply from the main gas supply cylinder 2 to the backup gas supply cylinder 3 by closing the control valve on the main gas supply cylinder 2 and opening the control valve on the backup gas supply cylinder 3, or switch the gas supply from the main gas supply cylinder 2 to the backup gas supply cylinder 3 by closing the first control valve 211 and opening the second control valve 311, and so on. Such flexible adjustments and changes do not deviate from the principles and scope of the present invention and should be included in the protection scope of the present invention.
[0047] Preferably, the switch from supplying gas to the incubator 1 from the main gas supply cylinder 2 to supplying gas to the incubator 1 from the backup gas supply cylinder 3 is implemented by closing the first control valve 211 and opening the second control valve 311 .
[0048] It should be noted that, in actual applications, technicians in this field can set a gas concentration sensor in the incubator 1, and obtain the gas concentration in the incubator 1 through the value of the gas concentration sensor, or set a gas concentration detector in the incubator 1, and obtain the gas concentration in the incubator 1 through the value of the gas concentration detector, and so on. Such adjustments and changes to the specific method of obtaining the gas concentration in the incubator 1 do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0049] Preferably, if Figure 1 As shown, a gas concentration sensor 11 is arranged in the incubator 1 .
[0050] Exemplarily, the incubator 1 is a carbon dioxide incubator, the gas is carbon dioxide, and a carbon dioxide concentration sensor is provided in the incubator 1, and the carbon dioxide concentration in the incubator 1 is obtained according to the value of the carbon dioxide concentration sensor.
[0051] It should be noted that, in practical applications, the control method of the present invention is not limited to the gas supply of carbon dioxide. For example, it can also be applied to the gas supply of oxygen, or it can also be applied to the gas supply of nitrogen, etc. Such flexible adjustments and changes do not deviate from the principle and scope of the present invention and should be included in the protection scope of the present invention.
[0052] It should also be noted that, in actual applications, technicians in this field can set the standard concentration to a fixed value, or set the standard concentration to a set value input by the user, etc. Such flexible adjustments and changes do not deviate from the principles and scope of the present invention and should be included in the protection scope of the present invention.
[0053] Exemplarily, the standard concentration is set to a fixed value, such as 15.0%.
[0054] It should be noted that, in actual applications, those skilled in the art may first calculate the difference between the gas concentration and the standard concentration, and then compare the difference with a preset value, or first calculate the ratio of the gas concentration to the standard concentration, and then compare the ratio with a preset value, or directly compare the gas concentration with the standard concentration, and so on. Such flexible adjustments and changes do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0055] Continue reading Figure 2 , and then see Figure 3 , Figure 3 is a flow chart of an embodiment of a control method of the present invention.
[0056] Preferably, if Figure 2 and Figure 3 As shown, "According to the gas concentration C 1 and standard concentration C 0 The specific steps of selectively switching to the standby gas supply cylinder 3 to supply gas to the incubator 1 include:
[0057] S210: Calculate the first difference △ 1 =C 0 -C 1 ;
[0058] S220: The first difference △ 1 With the first preset value A 1 Make comparisons;
[0059] S230: According to the comparison result, selectively switch to using the spare gas supply cylinder 3 to supply gas to the incubator 1.
[0060] By such a setting, the difference between the gas concentration in the incubator 1 and the standard concentration and the first preset value A 1 By comparison, compared with directly comparing the gas concentration with the standard concentration, it is possible to avoid misjudgment of the gas concentration in the incubator 1 due to detection errors of the gas concentration in the incubator 1, thereby making the judgment of switching between the main gas supply cylinder 2 and the backup gas supply cylinder 3 more accurate.
[0061] It should be noted that, in practical applications, technicians in this field can set the unit of gas concentration to a percentage, or they can set the unit of gas concentration to ppm, etc. Such flexible adjustment and change of the unit of gas concentration does not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0062] Exemplarily, the unit of the gas concentration is set to percentage, such as the gas concentration is 15.0%.
[0063] It should be noted that those skilled in the art can set the first preset value A through experience or experiments. 1 The numerical value of .
[0064] Exemplarily, the first preset value is set to 1.0%.
[0065] like Figure 3 As shown, the specific steps of “selectively switching to supplying gas to the incubator 1 from the spare gas supply cylinder 3 according to the comparison result” include:
[0066] S231: If △ 1 ≤A 1 , the incubator 1 is not supplied with gas by the spare gas cylinder 3;
[0067] S232: If △1 >A 1 The duration reaches the first preset time T 1 , then further determine that at the second preset time T 2 Whether the gas concentration in the incubator 1 increases within a period of time; according to the judgment result, selectively switch to the backup gas supply cylinder 3 to supply gas to the incubator 1.
[0068] Through such a setting, on the one hand, when △ 1 ≤A 1 When , it indicates that the difference between the gas concentration in the incubator 1 and the standard concentration is small, that is, the main gas supply cylinder 2 can provide gas to the incubator 1 so that the concentration in the incubator 1 provides a suitable concentration of gas for the growth of cells and tissues in the incubator 1, and no switching is required at this time.
[0069] On the other hand, when △ 1 >A 1 The duration reaches the first preset time T 1 , further determine at the second preset time T 2 Whether the gas concentration in the incubator 1 increases within △ 1 >A 1 Then, it is further determined that at the second preset time T 2 By monitoring whether the gas concentration in the incubator 1 is lower than the standard concentration for a period of time exceeding the first preset time T 1 Then further determine at the second preset time T 2 Whether the gas concentration in the incubator 1 increases within a certain period of time can avoid the error of gas concentration detection causing △ 1 >A 1 The misjudgment caused by △ 1 >A 1 The duration reaches the first preset time T 1 , indicating that the gas concentration in the incubator 1 is lower than the standard concentration for a period of time. At this time, it is possible that the gas volume in the main gas supply cylinder 2 is insufficient, or there is no gas in the main gas supply cylinder 2. Therefore, it is necessary to further determine whether the gas concentration in the second preset time T 2 Whether the gas concentration in the incubator 1 increases within a certain period of time can be used to determine whether the main gas supply cylinder 2 is still supplying gas to the incubator 1.
[0070] It should be noted that in practical applications, it is not limited to when △ 1 >A 1 The duration reaches the first preset time T 1 When further determining at the second preset time T 2Whether the gas concentration in the incubator 1 increases within △ 1 >A 1 , then further determine that at the second preset time T 2 Whether the gas concentration in the incubator 1 increases, etc., such flexible adjustment and change does not deviate from the principle and scope of the present invention and should be included in the protection scope of the present invention.
[0071] Of course, it is preferably set to 1 >A 1 The duration reaches the first preset time T 1 When further determining at the second preset time T 2 Whether the gas concentration in the incubator 1 increases.
[0072] With this setting, as long as △ 1 >A 1 When further determining at the second preset time T 2 Compared with whether the gas concentration in incubator 1 increases, when △ 1 >A 1 The duration reaches the first preset time T 1 Then, it is further determined that at the second preset time T 2 Whether the gas concentration in the incubator 1 increases within a certain period of time can avoid the error of gas concentration detection causing a △ 1 >A 1 The misjudgment caused by the situation can be avoided, thereby making the judgment of the difference between the gas concentration in the incubator 1 and the standard concentration more accurate, and the judgment of the switch between the main gas supply cylinder 2 and the backup gas supply cylinder 3 more precise.
[0073] Exemplarily, the first preset time T is set 1 180s, standard concentration C 0 is 15.0%, the first preset value A 1 The value is 1.0%. The following describes an embodiment in which the gas supply to the incubator 1 is not switched to the standby gas supply cylinder 3 in combination with the following situations.
[0074] Case 1: If the detected gas concentration C in incubator 1 1 is 14.0%, then the first difference △ 1 =15.0%-14.0%, that is, △ 1 =1.0%,△ 1 =A 1 At this time, the gas supply to the incubator 1 is not switched to the backup gas supply cylinder 3 .
[0075] Scenario 2: If the detected gas concentration C in incubator 1 is1 is 14.5%, then the first difference △ 1 =15.0%-14.5%, that is, △ 1 =0.5%,△ 1 <A 1 At this time, the gas supply to the incubator 1 is not switched to the backup gas supply cylinder 3.
[0076] Scenario 3: If the detected gas concentration C in incubator 1 is 1 is 13.0%, then the first difference △ 1 =15.0%-13.0%, that is, △ 1 =2.0%,△ 1 >A 1 , but 1 >A 1 The duration is only 150 seconds, and at this time, the gas supply to the incubator 1 is not switched to the backup gas cylinder 3.
[0077] Exemplarily, the first preset time T is set 1 180s, standard concentration C 0 is 15.0%, the first preset value A 1 If the detected gas concentration C in the incubator 1 is 1.0%, 1 is 13.0%, then the first difference △ 1 =15.0%-13.0%, that is, △ 1 =2.0%,△ 1 >A 1 , and △ 1 >A 1 The duration is 180s, then further determine that in the second preset time T 2 Whether the gas concentration in the incubator 1 increases.
[0078] Preferably, “determining at the second preset time T 2 The specific steps of "whether the gas concentration in the incubator 1 increases" include:
[0079] Calculate the second difference △ 2 =C i+n -C i ;
[0080] The second difference △ 2 With the second preset value A 2 Make comparisons;
[0081] If 2 >A 2 , it is determined that at the second preset time T 2 The gas concentration in the incubator 1 increases;
[0082] Among them, C i is the gas concentration in the incubator 1 obtained at the beginning of the judgment, C i+n It is the gas concentration in the incubator 1 obtained every n set time periods after the judgment starts.
[0083] By such setting, that is, by calculating the second preset time T 2 The difference between the gas concentrations in the incubator 1 obtained twice is △ 2 Is it greater than the second preset value A? 2 , to determine whether the gas concentration in the incubator 1 increases, compared with directly comparing the gas concentrations in the incubator 1 obtained twice, it can avoid misjudgment caused by detection errors of the gas concentration in the incubator 1, making the judgment result more reliable.
[0084] It should be noted that, in practical applications, when determining whether the gas concentration in the incubator 1 is increased, the technicians in this field may first obtain the gas concentration in the incubator 1 (i.e., C i ), as the reference concentration for judging whether the gas concentration is increasing, and then obtain the gas concentration in the incubator 1 every n set time (i.e., C i+n ), C i+n With C i Alternatively, the gas concentration in the incubator 1 can be continuously obtained during the entire control process. In this case, the gas concentration in the incubator 1 obtained at the beginning of the judgment (i.e., C i ), as a reference concentration for judging whether the gas concentration has increased, and then the gas concentration in the incubator 1 (i.e., C i+n ) and C i Such flexible adjustment and change do not deviate from the principle and scope of the present invention and should be limited within the protection scope of the present invention. Of course, it is preferred to continuously obtain the gas concentration in the incubator 1 during the entire control process.
[0085] Exemplarily, the first preset time T is set 1 is 180s, the second preset time T 2 is 120s, the standard concentration is 15.0%, the set time is 10s, the first preset value A1 is 1.0%, and the second preset value A 2 It is 0.2%.
[0086] When 1 When the duration of >15.0% reaches 180s, the gas concentration in the incubator 1 detected at this time is recorded as C i , assuming C i = 13.0%, and the gas concentration in the incubator 1 obtained at an interval of 10s is Ci+1 =13.5%, the second difference △ 2 =C i+1 -C i =13.5%-13.0%=0.5%>0.2%, which means that the gas concentration in incubator 1 increased within 120s.
[0087] If C i+1 =13.0%, that is, △ 2 =0%<0.2%; then continue to calculate the gas concentration C in the incubator 1 obtained after another 10s interval i+2 With C i The difference of 2 , until △ 2 >0.2%.
[0088] However, if the gas concentration in incubator 1 obtained at 120 s is i The difference between 2 All of them were no more than 0.2%, indicating that the gas concentration in the incubator 1 did not increase within 120 s.
[0089] Preferably, the specific steps of “selectively switching to supplying gas to the incubator 1 from the spare gas supply cylinder 3 according to the judgment result” include:
[0090] If the judgment result is "yes", the gas supply to the incubator 1 by the spare gas supply cylinder 3 is not switched;
[0091] If the judgment result is "No", the gas supply of the main gas supply cylinder 2 is increased, and further judgment is made within the third preset time T 3 Whether the gas concentration in the incubator 1 increases;
[0092] According to the judgment result, the gas supply to the incubator 1 is selectively switched to the backup gas supply cylinder 3 .
[0093] By such a setting, on the one hand, if the second preset time T 2 If the gas concentration in the incubator 1 increases within a certain period of time, it means that the main gas supply cylinder 2 is still supplying gas to the incubator 1, that is, there is still residual gas in the main gas supply cylinder 2. Therefore, the gas supply to the incubator 1 is not switched to the backup gas supply cylinder 3 at this time to avoid wasting the residual gas in the main gas supply cylinder 2.
[0094] On the other hand, if at the second preset time T 2 If the gas concentration in the incubator 1 does not increase within the second preset time T, it may be that the main gas supply cylinder 2 has run out of gas. Alternatively, it may be that although there is still gas in the main gas supply cylinder 2, the pressure in the main gas supply cylinder 2 is insufficient and the gas intake is slow, resulting in the second preset time T. 2Within the third preset time T, the gas concentration in the incubator 1 does not increase. Therefore, it is necessary to further increase the gas supply of the main gas supply cylinder 2 and detect 3 Whether the gas concentration in the incubator 1 increases within a certain period of time can be used to determine whether the main gas supply cylinder 2 can supply gas to the incubator 1, and then to determine whether there is any residual gas in the main gas supply cylinder 2, thereby avoiding the waste of the residual gas in the main gas supply cylinder 2.
[0095] It should be noted that, in actual applications, those skilled in the art may increase the gas supply volume of the main gas supply cylinder 2 by adjusting the valve opening of the main gas supply cylinder 2 to the maximum opening, or may increase the opening of the first control valve 211, or may intervene in the PID control of the main gas supply cylinder 2 during normal gas supply, such as changing the duty cycle intake during normal gas supply to a fixed duty cycle intake, etc. Such adjustments and changes to the specific implementation method of increasing the gas supply volume of the main gas supply cylinder 2 do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0096] Preferably, the control method of the present invention further comprises: setting the increase in the gas supply amount of the main gas supply cylinder 2 to adjust the valve opening of the main gas supply cylinder 2 to a maximum opening.
[0097] It should be noted that, in practical applications, those skilled in the art may change the second preset time T 2 and the third preset time T 3 Alternatively, the second preset time T 2 and the third preset time T 3 Such flexible adjustments and changes do not deviate from the principle and scope of the present invention and should be included in the protection scope of the present invention.
[0098] Preferably, the second preset time T 2 and the third preset time T 3 Set to the same.
[0099] Exemplarily, the second preset time T 2 and the third preset time T 3 Both are set to 120s.
[0100] Preferably, the specific steps of “selectively switching to supplying gas to the incubator 1 from the spare gas supply cylinder 3 according to the judgment result” include:
[0101] If the judgment result is "yes", the gas supply to the incubator 1 by the spare gas supply cylinder 3 is not switched;
[0102] If the judgment result is "No", the gas supply to the incubator 1 is switched to the backup gas supply cylinder 3 .
[0103] Through such an arrangement, on the one hand, if after the gas supply of the main gas supply cylinder 2 is increased, the gas concentration in the incubator 1 increases within the third preset time, it means that there is still residual gas in the main gas supply cylinder 2. At this time, the gas supply to the incubator 1 is not switched to the backup gas supply cylinder 3, so as to avoid wasting the residual gas in the main gas supply cylinder 2. On the other hand, if after the gas supply of the main gas supply cylinder 2 is increased, the gas concentration in the incubator 1 still does not increase within the third preset time, it means that there is no residual gas in the main gas supply cylinder 2. At this time, it is necessary to switch to the backup gas supply cylinder 3 to supply the incubator 1, so as to avoid affecting the growth of cells and tissues in the incubator 1 due to insufficient gas supply in the incubator 1.
[0104] It should be noted that, it is determined that at the third preset time T 3 The specific steps and judgment of whether the gas concentration in the inner incubator 1 increases within the second preset time T 2 The specific steps for determining whether the gas concentration in the incubator 1 increases are the same as those for determining whether the gas concentration in the incubator 1 increases, and will not be repeated here.
[0105] It should be noted that, in actual applications, those skilled in the art may set the switching of the gas supply from the main gas supply cylinder 2 to the backup gas supply cylinder 3 to be performed by the user manually operating the first control valve 211 and the second control valve 311, or may set the first control valve 211 and the second control valve 311 to be electrically controlled valves, and set the switching of the gas supply from the main gas supply cylinder 2 to the backup gas supply cylinder 3 to be performed automatically, and so on. Such flexible adjustments and changes do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0106] Preferably, the gas supply system of the present invention further includes an alarm device.
[0107] It should be noted that, in actual applications, those skilled in the art may set the alarm device on the incubator 1, or may set the alarm device on the main gas supply cylinder 2, or may set the alarm device on the backup gas supply cylinder 3, and so on. Such adjustments and changes to the specific setting position of the alarm device do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0108] Preferably, if Figure 1 As shown, the alarm device 12 is arranged on the incubator 1 .
[0109] It should be noted that, in actual applications, those skilled in the art may configure the alarm device 12 as a sound alarm module, or may configure the alarm device 12 as a light alarm module, or may configure the alarm device 12 as a combination of sound and light alarm module, etc. Such adjustments and changes to the specific setting types of the alarm device 12 do not deviate from the principles and scope of the present invention, and should be included in the protection scope of the present invention.
[0110] Preferably, the alarm device 12 is configured as a sound and light combined alarm module.
[0111] Preferably, at the second preset time T 2 When the gas concentration in the incubator 1 does not increase within the time limit, the control method of the present invention further comprises: activating the alarm device 12.
[0112] Through such an arrangement, on the one hand, a low concentration alarm can be issued in the incubator 1 through the alarm device 12, and the user can be informed that the gas concentration in the incubator 1 is lower than the standard concentration, so that the user can understand the gas concentration in the incubator 1; on the other hand, the user can be reminded that the amount of gas in the main gas supply cylinder 2 is running low, and the gas supply to the incubator 1 will soon be switched to the backup gas supply cylinder 3.
[0113] It should be noted that, in practical applications, it is not limited to setting the alarm device 12 to be on the second preset time T 2 The alarm device 12 is activated when the gas concentration in the incubator 1 does not increase within a third preset time T. For example, the alarm device 12 can also be set to increase the gas supply of the main gas supply cylinder 2 and then start the alarm within the third preset time T. 3 The incubator 1 is started when the gas concentration does not increase within the second preset time T, etc. Such flexible adjustment and change do not deviate from the principle and scope of the present invention and should be included in the protection scope of the present invention. Of course, preferably, the second preset time T 2 The alarm device 12 is activated when the gas concentration in the incubator 1 does not increase within a certain period of time.
[0114] Preferably, the control method of the present invention further comprises: after the alarm device 12 is started, when the gas supply to the incubator 1 is switched to the backup gas supply cylinder 3, the alarm device 12 stops working.
[0115] Through such a setting, the user can be reminded that the switching of the gas supply system has been completed. On the one hand, the gas concentration in the incubator 1 will gradually return to the normal concentration, so that the user can understand the gas concentration in the incubator 1; on the other hand, the user can be reminded to replace the exhausted main gas supply cylinder 2 with a cylinder full of gas, so that when the gas in the spare gas supply cylinder 3 is exhausted, it can be switched to the main gas supply cylinder 2 to supply gas to the incubator 1.
[0116] Preferably, if Figure 3 As shown, the control method of the present invention also includes:
[0117] S233: If △ 1 >A 1 The duration reaches the fourth preset time T 4 When the incubator 1 is switched to the standby gas supply cylinder 3, the gas supply to the incubator 1 is switched to the standby gas supply cylinder 3.
[0118] With this setting, if △ 1 >A 1 The duration reaches the fourth preset time T 4 When the gas concentration in the incubator 1 is lower than the standard concentration for too long, timely switching to the standby gas supply cylinder 3 to supply gas to the incubator 1 can avoid the normal growth of cells and tissues in the incubator 1 being affected by the gas concentration in the incubator 1 being lower than the standard concentration for a long time.
[0119] It should be noted that the gas supply system of the present invention includes a controller, and the controller is configured to execute the control method introduced above.
[0120] It should also be noted that, in actual applications, those skilled in the art can configure the controller to be communicatively connected to the gas concentration sensor 11, the first control valve 211, the second control valve 311, and the alarm device 12, so as to realize intelligent collection of the gas concentration in the incubator 1, intelligent switching of the gas supply system, and intelligent reminder of the situation in the incubator 1.
[0121] It should also be noted that, although the specific embodiment of the present invention is described in conjunction with the main gas supply cylinder 2 first supplying gas to the incubator 1, and when the gas in the main gas supply cylinder 2 is exhausted, switching to the backup gas supply cylinder 3 to supply gas to the incubator 1, the control method of the present invention is also applicable to the situation where the backup gas supply cylinder 3 supplies gas to the incubator 1, and when the gas in the backup gas supply cylinder 3 is exhausted, switching to the main gas supply cylinder 2 to supply gas to the incubator 1, and so on. Such flexible adjustments and changes do not deviate from the principle and scope of the present invention, and should be included in the protection scope of the present invention.
[0122] So far, the technical solutions of the present invention have been described in conjunction with the preferred embodiments shown in the accompanying drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will fall within the protection scope of the present invention.
Claims
1. A control method for a gas supply system, It is characterized in that The gas supply system includes an incubator, a main gas supply cylinder and a spare gas supply cylinder, and the control method includes: Get the gas concentration C in the incubator 1 ; According to the gas concentration C 1 and standard concentration C 0 , selectively switching to supplying gas to the incubator from the standby gas supply cylinder; Calculate the first difference △ 1 =C 0 -C 1 ; The first difference △ 1 With the first preset value A 1 Make comparisons; If 1 ≤A 1 , the incubator is not supplied with gas by the standby gas supply cylinder; If 1 >A 1 The duration reaches the first preset time T 1 , then further determine that at the second preset time T 2 Whether the gas concentration in the incubator increases within the time period; According to the judgment result, the incubator is selectively supplied with gas from the backup gas supply cylinder.
2. The control method according to claim 1, It is characterized in that The specific steps of "selectively switching to supplying gas to the incubator from the standby gas supply cylinder according to the judgment result" include: If the judgment result is "yes", the incubator is not supplied with gas by the standby gas supply cylinder; If the judgment result is "no", the gas supply of the main gas supply cylinder is increased, and further judgment is made within the third preset time T 3 Whether the gas concentration in the incubator increases within the time period; According to the judgment result, the incubator is selectively supplied with gas from the backup gas supply cylinder.
3. The control method according to claim 2, It is characterized in that The specific steps of "selectively switching to supplying gas to the incubator from the standby gas supply cylinder according to the judgment result" include: If the judgment result is "yes", the incubator is not supplied with gas by the standby gas supply cylinder; If the judgment result is "no", switch to using the backup gas supply cylinder to supply gas to the incubator.
4. The control method according to claim 2, It is characterized in that The gas supply system further includes an alarm device. When the judgment result is "no", the control method further includes: Activate the alarm device.
5. The control method according to claim 2, It is characterized in that The specific steps of "increasing the gas supply volume of the main gas supply cylinder" include: Adjust the valve opening of the main gas supply cylinder to the maximum opening.
6. The control method according to claim 1, It is characterized in that The control method of the present invention further includes: If 1 >A 1 The duration reaches the fourth preset time T 4 When the incubator is switched to be supplied with gas by the standby gas supply cylinder.
7. The control method according to any one of claims 1 to 6, It is characterized in that "Judge in the second preset time T 2 The specific steps of "whether the gas concentration in the incubator increases" include: Calculate the second difference △ 2 =C i+n -C i ; The second difference △ 2 With the second preset value A 2 Make comparisons; If 2 >A 2 , it is determined that within the second preset time T 2 The gas concentration in the incubator increases within a period of time; Among them, C i is the gas concentration in the incubator obtained at the beginning of the judgment, C i+n It is the gas concentration in the incubator obtained every n set time periods after the judgment starts. 8 . An air supply system, comprising a controller, wherein the controller is configured to execute the control method according to claim 1 .
Citation Information
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