A serial specimen preparation method and system

Abstract

The present invention discloses a serial specimen preparation system, which belongs to the field of cell and bacteria detection. It includes a frame, a negative pressure generating device is provided on the frame, and the air extraction end of the negative pressure generating device is connected to the upper part of the waste liquid container through an air pipe. The upper end of the frame is provided with a workbench, and the workbench is provided with a mounting hole for placing a cup body. Below the mounting hole is provided a connecting pipe connected to the upper part of the waste liquid container. A support is provided above the workbench, and the support is mounted on the support. The liquid outlet at the lower end of the specimen container passes through the support and is connected to the upper end of the telescopic tube. The lower end of the telescopic tube is connected to a sealing cover, which is mounted on a lifting seat, and the lifting seat is connected to a lifting drive mechanism. The upper end of the workbench is provided with a pressing sampling device for pressing the filter membrane cup into the rubber seat. The purpose of the present invention is to automatically complete specimen filling and keep the target sample intercepted on the filter membrane within a reasonable range.

Description

Technical Field

[0001] The present invention relates to the field of cell and bacteria detection, and in particular to a serial specimen preparation method and system. Background Art

[0002] After collecting samples such as saliva, the samples usually need to be digested or pretreated to prepare specimens. Digestion and other pretreatments can inactivate harmful pathogens in the samples and remove interfering substances. After the sample digestion is completed, the liquid specimen needs to be extracted using a sampling device, and then the liquid specimen is filtered through a retention membrane (filter membrane) such as a microporous filter membrane to retain the target components.

[0003] For example, in a microporous filter membrane preparation device disclosed in patent publication number CN205981829U, a liquid specimen is dripped into a cup body, and then the cup body is placed in a negative pressure device. With the negative pressure, the liquid passes through the microporous filter membrane, and the target component is retained by the microporous filter membrane, thereby facilitating subsequent preparation and detection.

[0004] When using the above-mentioned membrane filter method to collect specimens for cell and bacterial testing, the amount of specimen that the membrane can filter can vary due to different specimen properties. Existing methods often rely on manual sample addition and visually observe the rate at which liquid flows through the microporous membrane to determine whether the filtration volume has reached the maximum flux of the microporous membrane, ensuring that more target components are retained and no specimen is wasted. However, due to the large variability in human judgment, this method can easily result in too little target being intercepted, affecting detection, or too much target being intercepted, causing clogging of the microporous membrane. Therefore, there is still room for improvement in the microporous membrane liquid sample addition and filtration method. Summary of the Invention

[0005] The purpose of the present invention is to address the above problems and provide a serial specimen preparation method and system that can automatically add liquid specimens and keep the target sample intercepted on the filter membrane within a reasonable range.

[0006] To achieve the above objectives, the technical solution adopted by the present invention is: a serial specimen preparation system, which includes a frame, a negative pressure generating device is provided on the frame, an air suction end of the negative pressure generating device is connected to the upper part of the waste liquid container through an air pipe, a workbench is provided at the upper end of the frame, a mounting hole for placing a cup body is provided on the workbench, and a connecting pipe connected to the upper part of the waste liquid container is provided below the mounting hole, so that the negative pressure generating device can absorb the gas in the cup body. In order to automatically connect the cup body with the specimen container, a support is provided above the workbench, and the specimen container is installed on the support. The liquid outlet pipe at the lower end of the specimen container passes through the support and is connected to the upper end of the telescopic tube, and the lower end of the telescopic tube is connected to the sealing cover, which is installed on the lifting seat, and the lifting seat is connected to the lifting drive mechanism; the lifting seat moves toward the cup body under the drive of the lifting drive mechanism, so that the sealing cover covers the upper end of the cup body, thereby completing the connection between the cup body and the specimen container.

[0007] The negative pressure generating device extracts the gas in the waste liquid container, the connecting pipe and the cup body, so that the liquid specimen in the specimen container enters the cup body. The liquid passes through the filter membrane at the lower end of the cup body and is drawn into the waste liquid container. The cells, bacteria and other target objects in the liquid specimen are intercepted by the filter membrane. As the number of target objects on the filter membrane increases, the pass rate of the filter membrane gradually decreases. When the suction generated by the negative pressure generating device is not enough to extract the specimen, the target objects on the filter membrane just meet the requirements.

[0008] Furthermore, in order to simplify the structure and facilitate observation by the inspectors, a piston adapted to its inner diameter is provided in the specimen container, and a push-pull rod is provided on the piston on the side opposite to the liquid outlet tube. When the suction force generated by the negative pressure generating device is not enough to move the piston, the target object on the filter membrane just meets the requirements.

[0009] Furthermore, in order to improve the level of automation, a sampling part is provided between the lifting seat and the workbench. A through hole is provided on the sampling part. A clamping device for clamping the cup body is provided in the through hole. The clamping device fixes the cup body and then moves with the sampling part, thereby automatically removing the cup body from the workbench.

[0010] Furthermore, a specific structure and installation method of the clamping device is that the interior of the sampling part is hollow, and the clamping device includes a first clamping part and a second clamping part placed on both sides of the cup body, the first clamping part is connected to the first driving part, and the second clamping part is connected to the second driving part.

[0011] Furthermore, a specific working mode of the clamping device and the sampling part is that the end surface of the sampling part is connected to the sliding part in a lifting manner, and the sliding part moves in the transverse direction; the support and the workbench slide relatively.

[0012] Furthermore, in order to ensure that the sampling portion moves along with the sliding portion, the upper portion of the sampling portion is magnetically connected to the extension portion on the sliding portion.

[0013] Furthermore, in order to make the sampling part and the sliding part adsorbed together, a spring in contact with the lower end surface of the sampling part is provided on the upper end of the workbench.

[0014] Furthermore, in order to make the sampling part and the sliding part adsorbed together, the lower end of the lifting seat and the upper end of the sampling part are connected magnetically.

[0015] Furthermore, in order to quickly complete the installation of the cup body and maintain the sealing of the connection, a rubber seat is provided in the installation hole, and a supporting mesh plate is provided in the rubber seat. The supporting mesh plate is in contact with the filter membrane, thereby ensuring that the filter membrane will not be damaged during negative pressure operation.

[0016] A method for preparing specimens using a serial specimen preparation system comprises the following steps:

[0017] First, the pre-treated specimen is placed in a sealed specimen container, which is then sealed and connected to the upper end of the cup body. A filter membrane is provided at the lower part of the cup body. The lower part of the cup body is sealed and connected to the upper part of the waste liquid container through a telescopic tube. The waste liquid container is connected to the air extraction end of the negative pressure generating device through an air pipe.

[0018] Second: The negative pressure generating device extracts the gas below the filter membrane, making the air pressure above the filter membrane greater than the air pressure below the filter membrane. Under the action of the pressure difference, the specimen in the specimen container enters the cup body, and the liquid in the specimen passes through the filter membrane into the waste liquid container. The target object in the specimen is stopped by the filter membrane;

[0019] 3: By detecting the air pressure under the specimen container or filter membrane, the negative pressure generating device is turned off to complete the specimen collection.

[0020] The beneficial effects of the present invention are: it solves the problem of large errors in judging whether the filtration volume of the filter membrane has reached the maximum flux by visually observing the liquid flow rate during the existing manual filling of liquid specimens; the present application uses a negative pressure generating device to draw the specimen in the specimen container into the cup body. As the number of target objects on the filter membrane increases, it becomes difficult for the gas in the cup body and the specimen container to pass through the filter membrane, so that the pressure difference generated by the negative pressure generating device cannot overcome the friction between the piston and the inner wall of the specimen container. At this time, the piston cannot be lowered, or a sensing unit such as an air pressure sensor and a negative pressure sensor is set at the connecting pipeline. The sensing unit sends a signal to the control unit. After the control unit analyzes the data, it turns off the negative pressure generating device, ensuring that the target objects on the filter membrane will not have a small retention amount or an excessive retention amount of the target objects, causing the filter membrane to be blocked, so that the target objects intercepted on the filter membrane are kept within a reasonable range.

[0021] 1. The lower end of the specimen container is connected to the sealing cover through a telescopic tube. The sealing cover moves in the vertical direction with the lifting seat. When the lifting seat descends, the sealing cover can be quickly connected in series with the cup body. After the specimen is filled, the sealing cover rises with the lifting seat and separates from the cup body, thereby automatically completing the disassembly and assembly of the cup body and the specimen container, improving efficiency.

[0022] 2. The cup body passes through the through hole on the sampling part. When the specimen is extracted, the clamping device in the sampling part fixes the cup body to prevent it from rising with the sealing cover. At the same time, when the sealing cover is separated from the cup body, the sampling part rises to connect with the extension part, so that the cup body is separated from the workbench, thereby improving the level of automation.

[0023] 3. The support and the sliding part can move relative to the workbench, so that the positions of the three can be staggered to simultaneously place a new cup, place a specimen container or clamp a specimen, and collect the cup containing the target object, thereby improving detection efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a front structural schematic diagram of the present invention in working state.

[0025] Figure 2 This is a schematic diagram of the front structure when the cup body is open.

[0026] Figure 3 It is a side structural schematic diagram of the present invention.

[0027] Figure 4 Schematic diagram of the internal structure of the sampling part in side view.

[0028] Figure 5 Schematic diagram of the internal structure of the sampling part from a top view.

[0029] Figure 6 It is a structural diagram of the rubber seat.

[0030] Figure 7 It is a structural diagram of the cup body.

[0031] Figure 8 Schematic diagram of the structure of the specimen container.

[0032] The text labels in the figure are as follows: 1. frame; 2. negative pressure generating device; 3. waste liquid container; 4. workbench; 5. cup body; 501. filter membrane; 6. connecting pipe; 7. support; 8. specimen container; 801. piston; 802. push-pull rod; 803. liquid outlet pipe; 9. telescopic tube; 10. sealing cover; 11. lifting seat; 12. lifting drive mechanism; 13. sampling part; 14. through hole; 15. first clamping part; 16. second clamping part; 17. first drive part; 18. second drive part; 19. sliding part; 20. extension part; 21. spring; 22. rubber seat; 23. support mesh plate; 24. guide rail; 25. pressing plate; 26. L-shaped plate; 27. first connecting rod; 28. second connecting rod. DETAILED DESCRIPTION

[0033] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention is described in detail below with reference to the accompanying drawings. The description in this part is only exemplary and explanatory and should not have any limiting effect on the scope of protection of the present invention.

[0034] Example 1, as Figure 1-3 As shown in Figures 6-8, the specific structure of the present invention is a serial specimen preparation system, which includes a frame 1, on which a negative pressure generating device 2 is provided. The negative pressure generating device 2 can adopt a negative pressure pump. The suction end of the negative pressure generating device 2 is connected to the upper part of the waste liquid container 3 through an air pipe. A workbench 4 is provided at the upper end of the frame 1, and a mounting hole for placing a cup body 5 is provided on the workbench 4. A rubber seat 22 is provided in the mounting hole. The rubber seat 22 can adopt a sealing structure for negative pressure suction of a microporous filter membrane cup disclosed in the patent with publication number CN208420488U, and a supporting mesh plate 23 is provided in the rubber seat 22.

[0035] A connecting pipe 6 connected to the upper part of the waste liquid container 3 is provided below the installation hole. A support 7 is provided above the workbench 4 , and a specimen container 8 is installed on the support 7 .

[0036] The specimen container 8 can be a syringe with the needle removed or other sealed container. The pressure inside the specimen container 8 is lower than the external air pressure. In this embodiment, a piston 801 adapted to its inner diameter is provided in the specimen container 8. A push-pull rod 802 is provided on the piston 801 on the opposite side of the liquid outlet pipe 803. The liquid outlet pipe 803 at the lower end of the specimen container 8 passes through the support 7 and is connected to the upper end of the telescopic tube 9. The telescopic tube 9 can be a plastic hose, etc. The lower end of the telescopic tube 9 is connected to the sealing cover 10, and the sealing cover 10 is installed on the lifting seat 11. The lifting seat 11 is connected to the lifting drive mechanism 12. The lifting drive mechanism 12 can be a hydraulic cylinder, an electric push rod, etc. In this embodiment, a cylinder is used, and the lifting drive mechanism 12 is installed on the support.

[0037] Specific detection process: The operator extends the liquid outlet tube 803 of the specimen container 8 into the digestion container. At this time, the piston 801 is located at the proximal end of the liquid outlet tube 803. Then, the operator pulls the piston 801 toward the distal end of the liquid outlet tube 803, so that the sample enters the specimen container 8 from the liquid outlet tube 803.

[0038] The specimen container 8 containing the sample is clamped to the support 7. A countersunk hole can be set on the support 7. The inner diameter of the countersunk hole is adapted to the outer diameter of the specimen container 8. A through hole is set at the bottom of the countersunk hole so that the liquid outlet pipe 803 can extend out of the lower end of the support 7. Then the upper end of the telescopic tube 9 is fixed to the liquid outlet pipe 803, and the lower end of the telescopic tube 9 is fixed to the liquid inlet pipe at the upper end of the sealing cover; the sealing cover 10 is a shell structure with an open lower end. A soft rubber layer can be set on the inner wall of the sealing cover. The soft rubber layer is made of rubber, silicone, etc., and the inner diameter of the soft rubber layer is less than or equal to The outer diameter of the cup body 5, the inner wall of the sealing cover is still provided with a pressing plate 25, and the pressing plate 25 is located above the side wall of the cup body 5. The cup body 5 can adopt the cup body structure adopted in a microporous filter membrane making device disclosed in publication number CN205981829U; the connection method of the sealing cover 10 and the lifting seat 11 can be to provide a through hole on the lifting seat 11, and the sealing cover 10 is tightly matched with the through hole, or the sealing cover 10 is connected to the through hole by a thread, or the sealing cover 10 can be fixed to the lifting seat 11 by means of snaps, bolts, etc.

[0039] The inspector installs the cup body 5 into the rubber seat 22. After the above work is completed, the lifting seat 11 moves toward the cup body 5 under the drive of the lifting drive mechanism 12, so that the sealing cover 10 wraps the upper part of the cup body 5. The soft rubber layer can ensure the sealing of the connection between the cup body 5 and the sealing cover 10, and the clamping plate 25 contacts the upper end of the cup body 5, so that the cup body 5 descends, ensuring that the filter membrane 501 contacts the supporting mesh plate 23. At this time, the waste liquid container 3, the connecting pipe 6, the cup body 5 and the specimen container 8 are connected in series into a whole.

[0040] Then turn on the negative pressure generating device 2, which extracts the gas in the waste liquid container 3, the connecting pipe 6, and the cup body 5, thereby generating a pressure difference with the upper end of the piston. The pressure difference between the cup body 5 and the top of the piston 801 pushes the piston down, and allows the sample in the specimen container 8 to flow into the cup body 5.

[0041] The liquid in the sample flows through the filter membrane 501 into the waste liquid container 3 along with the airflow generated by the negative pressure generating device 2. The cells, bacteria and other target objects in the sample are intercepted by the filter membrane 501. As the number of target objects on the filter membrane 501 increases, the permeability of the filter membrane 501 gradually decreases, and the suction force of the negative pressure generating device 2 on the filter membrane 501 gradually decreases. When the suction force generated by the pressure difference cannot overcome the friction between the piston and the inner wall of the specimen container 8, the piston 801 will not move downward, and the filter membrane 501 reaches the optimal flux. The operator closes the negative pressure generating device 2 by observing the movement process of the piston 801 to complete the preparation of the specimen.

[0042] Example 2, as Figure 1 As shown, the specific structure and working mode of this embodiment refer to Example 1, but in this embodiment, a sensing unit is provided on the connecting pipe 4. The sensing unit can adopt an air pressure sensor, a negative pressure sensor, etc. The detection data of the sensing unit is sent to the control unit, and the processor, single-chip microcomputer and other processing systems in the control unit analyze the data. Then, based on the analysis results, the control unit sends an instruction to the negative pressure generating device 2.

[0043] Specific detection process: The liquid in the sample flows into the waste liquid container 3 through the filter membrane 501 along with the airflow generated by the negative pressure generating device 2. The target objects such as cells and bacteria in the sample are intercepted by the filter membrane 501. As the number of target objects on the filter membrane 501 increases, the permeability of the filter membrane 501 gradually decreases. The air above the filter membrane 501 has difficulty passing through the filter membrane 501, which reduces the air pressure in the waste liquid container 3 and the connecting pipe 6. At this time, the sensor unit sends the detection data to the control unit, which is connected to the negative pressure generating device 2. After analyzing the data, the control unit sends a shutdown instruction to the negative pressure generating device 2, and then the negative pressure generating device 2 stops working, completing one sample filling. The above can be controlled by a PLC system.

[0044] Example 3, as Figure 1-5 As shown, the specific structure and working method of this embodiment refer to embodiment 1 or 2, but in this embodiment, a sampling portion 13 is provided between the lifting base 11 and the workbench 4. The sampling portion 13 is provided with a through hole 14, and a clamping device for clamping the cup body 5 is provided in the through hole 14. The clamping device can be an air bag provided on the inner wall of the through hole 14. When the cup body 5 needs to be clamped, air is pumped into the air bag to expand the air bag, thereby clamping the cup body 5. Alternatively, a pneumatic clamping finger can be used.

[0045] In this embodiment, the interior of the sampling portion 13 is hollow, and the clamping device includes a first clamping portion 15 and a second clamping portion 16 placed on both sides of the cup body 5. The first clamping portion 15 is connected to the first drive portion 17, and the second clamping portion 16 is connected to the second drive portion 18. When multiple cup bodies 5 are arranged side by side, the first clamping portion 15 and the second clamping portion 16 are staggered, and two adjacent first clamping portions 15 are connected by a first connecting rod 27, and two adjacent second clamping portions 16 are connected by a second connecting rod 28. The second connecting rod 28 passes through the through hole on the first clamping portion 15, thereby realizing linkage. The second drive portion 18 and the first drive portion 17 can be hydraulic cylinders, electric push rods, etc. In this embodiment, a cylinder arranged at the lower end of the sampling portion 13 is used.

[0046] Clamping process: the cup body 5 is inserted into the through hole 14. When the cup body 5 needs to be clamped, the first driving part 17 and the second driving part 18 respectively drive the first clamping part 15 and the second clamping part 16 to move toward each other, thereby fixing the cup body 5.

[0047] Example 4, as Figure 1-3 As shown, the specific structure and working mode of this embodiment refer to embodiments 1-3, but in this embodiment, horizontal guide rails 24 are arranged at intervals along the vertical direction on the frame 1, and an L-shaped plate 26 is provided on the end face of the sampling portion 13. The upper end face of the L-shaped plate 26 is higher than the upper end face of the sampling portion 13, and the upper end face of the L-shaped plate 26 is connected to the sliding portion 19 through a vertical keyway. The sliding portion 19 is a plate-like structure with a through middle portion. The sliding portion 19 and the support 7 are respectively arranged on the guide rails 24, and the sliding portion 19 and the support 7 are driven to move by a rodless cylinder or the like.

[0048] The specific testing process is as follows: in the initial state, the sliding portion 19 and the support 7 are placed on the left and right sides of the workbench 4. The tester loads the specimen container 8 onto the support 7. The sliding portion 19 and the support 7 then slide to the top of the workbench 4. The lifting seat 11 descends, driving the sampling portion 13 downward, allowing the cup 5 to be inserted into the through hole 14. When the sealing cover 10 contacts the cup 5, the negative pressure generating device 2 begins to operate. After the specimen preparation is completed, the lifting seat 11 and the sampling portion 13 rise. During the ascending process of the sampling portion 13, the cup 5 is taken out of the rubber seat 22 by the clamping device. The sliding portion 19 and the support 7 then slide to the left and right sides of the workbench 4, respectively. At this point, there are three working areas: the support 7, where the tester is responsible for replenishing or replacing the sample; the workbench 4, where the tester is responsible for placing a new cup 5 in the rubber seat 22; and the sliding portion 19, where the tester removes the specimen and cup 5. After these operations are completed, a new specimen preparation can begin, thereby improving efficiency.

[0049] Example 5, as Figure 1-2 As shown, the specific structure and working mode of this embodiment refer to Example 4, but in this embodiment, the upper portion of the sampling portion 13 is magnetically connected to the extension portion 20 on the sliding portion 19, and the extension portion 20 extends toward the center line of the sampling portion 13. The distance between the extension portions 20 on both sides is greater than the outer diameter of the lifting seat 11, so that the lifting seat 11 can pass through the extension portion 20. The outer diameter of the sampling portion 13 is greater than the distance between the extension portions 20 on both sides. The sampling portion 13 rises to the extension portion 20 and is adsorbed together, so that the sampling portion 13 and the sliding portion 19 can move laterally together.

[0050] To allow the sampling portion 13 to rise and attach to the extension portion 20, a spring 21 is installed at the upper end of the workbench 4, contacting the lower end surface of the sampling portion 13. When the lifting base 11 pushes the sampling portion 13 downward, the spring 21 is compressed. To prevent the spring 21 from tilting, it can be placed on the outside of the telescopic tube. After the lifting base 11 rises, the sampling portion 13 is no longer restrained by the lifting base 11, and the spring 21 rebounds, pushing the sampling portion 13 up, so that the sampling portion 13 and the extension portion 20 are attached together.

[0051] Alternatively, the lower end of the lifting seat 11 is magnetically connected to the upper end of the sampling portion 13. When the lifting seat 11 rises, the sampling portion 13 moves upward together with the lifting seat 11 until the sampling portion 13 is blocked by the extension portion 20 and cannot continue to move upward, while the lifting seat 11 continues to move upward, at which time the sampling portion 13 and the lifting seat 11 are separated.

[0052] It should be noted that, in this article, the terms "comprises", "includes" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, article or apparatus that includes a series of elements includes not only those elements, but also includes other elements not explicitly listed, or also includes elements that are inherent to such process, method, article or apparatus.

[0053] This article uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only used to help understand the method of the present invention and its core ideas. The above is only a preferred implementation method of the present invention. It should be pointed out that due to the limitations of textual expression, there are objectively infinite specific structures. For ordinary technicians in this technical field, without departing from the principles of the present invention, they can make several improvements, modifications or changes, and can also combine the above technical features in an appropriate manner; these improvements, modifications, changes or combinations, or the direct application of the inventive concept and technical solution to other occasions without improvement, should be regarded as the scope of protection of the present invention.

Claims

1. A serial specimen preparation system, comprising a frame (1), wherein a negative pressure generating device (2) is provided on the frame (1), and an air extraction end of the negative pressure generating device (2) is connected to the upper part of a waste liquid container (3) through an air pipe, characterized in that: A workbench (4) is provided at the upper end of the frame (1), a mounting hole is provided on the workbench (4), a rubber seat (22) is provided in the mounting hole, a cup body (5) is placed in the rubber seat (22), a filter membrane (501) is provided below the cup body (5), a connecting pipe (6) connected to the upper part of the waste liquid container (3) is provided below the mounting hole, a support (7) is provided above the workbench (4), a specimen container (8) is installed on the support (7), a liquid outlet pipe (803) at the lower end of the specimen container (8) passes through the support (7) and is connected to the upper end of the telescopic tube (9), the telescopic tube (9) The lower end is connected to the sealing cover (10), the sealing cover (10) is installed on the lifting seat (11), the lifting seat (11) is connected to the lifting drive mechanism (12), a sampling part (13) is provided between the lifting seat (11) and the workbench (4), the sampling part (13) is provided with a through hole (14), and a clamping device for clamping the cup body (5) is provided in the through hole (14); a piston (801) adapted to the inner diameter of the specimen container (8) is provided in the specimen container (8), and a push-pull rod (802) is provided on the piston (801) on the side opposite to the liquid outlet pipe (803).

2. A serial specimen preparation system according to claim 1, characterized in that: The sampling portion (13) is hollow inside, and the clamping device includes a first clamping portion (15) and a second clamping portion (16) placed on both sides of the cup body (5), the first clamping portion (15) is connected to the first driving portion (17), and the second clamping portion (16) is connected to the second driving portion (18).

3. The serial specimen preparation system according to claim 1, characterized in that: The end surface of the sampling portion (13) is connected to the sliding portion (19) in a lifting manner, and the sliding portion (19) moves in the transverse direction; the support (7) and the workbench (4) slide relative to each other.

4. The serial specimen preparation system according to claim 3, characterized in that: The upper portion of the sampling portion (13) is magnetically connected to the extension portion (20) on the sliding portion (19).

5. The serial specimen preparation system according to claim 4, characterized in that: The upper end of the workbench (4) is provided with a spring (21) that contacts the lower end surface of the sampling portion (13).

6. The serial specimen preparation system according to claim 4, characterized in that: The lower end of the lifting seat (11) and the upper end of the sampling portion (13) are connected magnetically.

7. The serial specimen preparation system according to claim 4, characterized in that: A supporting mesh plate (23) is provided in the adhesive seat (22).

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