Sample Detection Method and Sample Analyzer

Abstract

An embodiment of the present invention discloses a sample detection method, which is applied to a sample analyzer. The sample analyzer includes: a reaction cup transfer module; the method includes: during the detection process, controlling the reaction cup transfer module to transfer a reaction cup from a first position to a second position, and performing a mixing operation during the transfer from the first position to the second position; detecting based on the mixed sample. This sample detection method not only has a simple process, strong reagent compatibility, but also a fast detection speed. In addition, a sample analyzer is also provided.

Description

Technical Field

[0001] The present invention relates to the technical field of medical detection, and particularly to a sample detection method and a sample analyzer. Background Art

[0002] The processing flow of existing sample analyzers is usually to first add a sample to a dry and clean reaction cup, then use a gripper to transfer the reaction cup to a constant temperature module (incubation module) for incubation to 37 degrees, then transfer the reaction cup to the position for adding reagents. After the reagent needle adds the reagents, the gripper grabs and mixes the reaction cup, and then transfers it to the detection module for detection. After the detection is completed, the gripper transfers the reaction cup to the waste cup bin position.

[0003] It can be seen from this working method that after the reagent is added to the reaction cup, first the gripper grabs the reaction cup from the reagent addition position, then mixes it, and after mixing, places it in the detection channel for detection. It can be seen that there are too many actions that need to occupy time between adding the reagent and starting the detection. For some detection items with very short reaction times, such as the FIB item, the higher the concentration of sample FIB, the shorter the reaction time. According to this process, when the reaction cup is placed in the detection channel, the reaction has already started, and the true reaction time collected by the collection channel is seriously insufficient, resulting in an untrue result. In the prior art, to solve this problem, usually the reagent is modified to extend the start reaction time after the reagent is mixed with the sample to make up for this problem. However, modifying the reagent is a very complex and troublesome thing, which requires a lot of manpower and material resources, and also limits the reagent compatibility of the instrument. Therefore, there is an urgent need to provide a sample detection method with a simple reaction process, strong reagent compatibility, and fast detection speed. Summary of the Invention

[0004] Based on this, in view of the above problems, it is necessary to propose a sample detection method and a sample analyzer with a simple process, strong reagent compatibility, and fast detection speed.

[0005] A sample detection method is applied to a sample analyzer, and the sample analyzer includes: a reaction cup transfer module;

[0006] The method includes:

[0007] During the detection process, control the reaction cup transfer module to transfer the reaction cup from a first position to a second position, and perform a mixing operation during the transfer from the first position to the second position;

[0008] Perform detection based on the mixed sample.

[0009] In one embodiment, the first position is a reagent addition position, and the second position is a detection module; controlling the reaction cup transfer module to transfer the reaction cup from the first position to the second position and performing a mixing operation during the transfer from the first position to the second position includes: controlling the reaction cup transfer module to transfer the reaction cup with added reagent from the reagent addition position to the detection module and performing a mixing operation during the transfer to the detection module.

[0010] In one embodiment, the sample analyzer further includes: an incubation module, a reagent addition position, and a detection module; before controlling the reaction cup transfer module to transfer the reaction cup from the first position to the second position and performing a mixing operation during the transfer from the first position to the second position, it further includes: controlling the reaction cup transfer module to place the reaction cup with added sample into the incubation module, and the incubation module is used to incubate the sample in the reaction cup; controlling the reaction cup transfer module to transfer the incubated reaction cup to the reagent addition position, and controlling the reagent needle to run to the reagent addition position to add the reagent; performing detection based on the mixed sample includes: controlling the detection module to perform detection based on the mixed sample.

[0011] In one embodiment, controlling the reaction cup transfer module to transfer the reaction cup with added reagent from the reagent addition position to the detection module and performing a mixing operation during the transfer to the detection module includes: obtaining a preset mixing time corresponding to the item to be tested, and determining the target moving speed of the reaction cup transfer module according to the preset mixing time; controlling the reaction cup transfer module to transfer the reaction cup with added reagent to the detection module at the target moving speed and performing a mixing operation during the transfer.

[0012] In one embodiment, determining the target moving speed of the reaction cup transfer module according to the preset mixing time includes: obtaining a preset transfer time, where the preset transfer time refers to the transfer time when the reaction cup transfer module transfers the reaction cup from the reagent addition position to the detection module at a preset transfer speed; when the preset mixing time is not greater than the preset transfer time, using the preset transfer speed as the target moving speed; when the preset mixing time is greater than the preset transfer time, calculating the target moving speed according to the preset mixing time and the transfer distance, and the transfer distance is the moving distance when the reaction cup transfer module transfers the reaction cup from the reagent addition position to the detection module.

[0013] In one embodiment, controlling the reaction cup transfer module to transfer the reaction cup with added reagents to the detection module at the target moving speed and performing a mixing operation during the transfer includes: when the preset mixing time is not greater than the preset transfer time, determining a mixing start position and a mixing end position; controlling the reaction cup transfer module to transfer at the target moving speed, starting the mixing operation when reaching the mixing start position, and stopping the mixing operation when reaching the mixing end position.

[0014] In one embodiment, the mixing end position is a position that has not reached the detection module to ensure that the liquid level of the mixed sample is restored to calm when reaching the detection module.

[0015] In one embodiment, the reagent addition position is a virtual reagent addition position, and the virtual reagent addition position is located at a suspended position.

[0016] In one embodiment, the sample analyzer further includes: a virtual sample addition position; the method includes: controlling the reaction cup transfer module to clamp the reaction cup and stay at the virtual sample addition position; controlling the sample addition needle to run to the virtual sample addition position to add a sample to the reaction cup.

[0017] In one embodiment, the first position is a sample addition position, and the second position is an incubation module; during the detection process, controlling the reaction cup transfer module to transfer the reaction cup from the first position to the second position and performing a mixing operation during the transfer from the first position to the second position includes: obtaining a test item to be tested, and when the test item to be tested is a dilution type item, controlling the reaction cup with added diluent and sample to be transferred to the incubation module and performing a mixing operation during the transfer to the incubation module.

[0018] In one embodiment, the reaction cup transfer module includes: a motion mechanism and a mixing mechanism, where the motion mechanism is used to grab and transfer the reaction cup, and the mixing mechanism performs a mixing operation on the sample and reagent in the reaction cup.

[0019] A sample analyzer includes: a reaction cup transfer module, a first position, and a second position; wherein, the reaction cup transfer module is used to transfer the reaction cup from the first position to the second position, perform a mixing operation during the transfer from the first position to the second position, and perform detection based on the mixed sample.

[0020] In one embodiment, the first position is a reagent addition position, and the second position is a detection module; using the reaction cup transfer module to transfer the reaction cup with added reagents from the reagent addition position to the detection module and performing a mixing operation during the transfer to the detection module.

[0021] In one embodiment, the sample analyzer further includes: an incubation module and a controller; the incubation module and the detection module are arranged in sequence; the reaction cup transfer module is located above the incubation module and the detection module; the controller is connected to the incubation module, the detection module, and the reaction cup transfer module; wherein, the reaction cup transfer module is used to transfer the incubated reaction cup to the reagent addition position, and the reagent needle is controlled to run to the reagent addition position to add reagents; after the reagents are added, the controller controls the reaction cup transfer module to transfer the reaction cup to the detection module, and a mixing operation is performed during the transfer to the detection module.

[0022] In one embodiment, the reaction cup transfer module includes: a motion mechanism and a mixing mechanism, the motion mechanism is used to grab the reaction cup and transfer it, and the mixing mechanism performs a mixing operation on the sample and reagents in the reaction cup.

[0023] In one embodiment, the reagent addition position is a virtual reagent addition position, and the virtual reagent addition position is located at a suspended position.

[0024] In one embodiment, the sample analyzer further includes: a virtual sample addition position, and the virtual sample addition position is arranged at a suspended position.

[0025] For the above sample detection method and sample analyzer, in order to avoid inaccurate results caused by too fast reaction, the reaction cup is transferred from the first position to the second position in a manner of mixing while transferring. Compared with the traditional method of transferring first and then mixing, this method is equivalent to performing the transfer operation and the mixing operation in parallel, greatly saving time, being beneficial to improving the accuracy of the detection result, and compared with the traditional method that requires modifying reagents, this method not only has a simple process, strong reagent compatibility, but also a fast detection speed. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0027] Among them:

[0028] Figure 1 is a flowchart of the sample detection method in one embodiment;

[0029] Figure 2 is a flowchart of the method of mixing during the transfer in one embodiment;

[0030] Figure 3 is a structural block diagram of a sample analyzer in one embodiment;

[0031] Figure 4 is a structural block diagram of a sample analyzer in another embodiment. Specific Embodiments

[0032] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0033] As Figure 1 shown, a sample detection method is proposed, which is applied to a sample analyzer. The sample analyzer includes: a reaction cup transfer module;

[0034] The above sample detection method includes:

[0035] Step 102, during the detection process, control the reaction cup transfer module to transfer the reaction cup from the first position to the second position, and perform a mixing operation during the transfer from the first position to the second position;

[0036] Among them, the sample analyzer can specifically be a coagulation analyzer. The reaction cup transfer module is implemented by a transfer device and is used to transfer the reaction cup from one position to another. For example, a gripper can be used to grab the reaction cup and then transfer it. Compared with the traditional method that requires transfer first and then mixing, in this embodiment of the invention, the mixing operation is performed during the transfer, which is equivalent to performing the transfer operation and the mixing operation in parallel, greatly saving time, being beneficial to improving the accuracy of the detection result, and increasing the detection speed.

[0037] The first position and the second position can be custom-set according to actual needs. In one embodiment, the first position is the reagent addition position, and the second position is the detection position. Reagent is added to the sample in the reaction cup at the reagent addition position, and after the addition, the operation of transferring while mixing is adopted to achieve the purpose of saving time. In another embodiment, the first position is the sample addition position, and the second position is the incubation position. For some test items, two or more samples need to be added during sample addition, so mixing is also required after sample addition. The method of transferring while mixing is adopted to save time. For example, for dilution-type items, the sample and the diluent need to be added simultaneously during sample addition, and then mixing is required.

[0038] Step 104, perform detection based on the mixed sample.

[0039] Among them, after the sample in the reaction cup is mixed evenly, detection is performed based on the evenly mixed sample. Specifically, the magnetic bead method or the optical method can be used for detection.

[0040] For the above sample detection method, in order to avoid false results caused by too fast reaction, the reaction cup is transferred from the first position to the second position in a manner of mixing while transferring. Compared with the traditional method of transferring first and then mixing, this method is equivalent to performing the transfer operation and the mixing operation in parallel, greatly saving time, being beneficial to improving the accuracy of the detection result, and compared with the traditional method that requires modifying reagents, this method not only has a simple process, strong reagent compatibility, but also a fast detection speed.

[0041] In one embodiment, the first position is the reagent addition position, and the second position is the detection module; the reaction cup transfer module is controlled to transfer the reaction cup from the first position to the second position, and a mixing operation is performed during the process of transferring from the first position to the second position, including: controlling the reaction cup transfer module to transfer the reaction cup with added reagent from the reagent addition position to the detection module, and performing a mixing operation during the process of transferring to the detection module.

[0042] Among them, in the specific scenario of a sample analyzer, the first position is the reagent addition position. The reagent addition position can be a physical reagent addition position or a virtual reagent addition position. The physical reagent addition position means that there is a support device for placing the reaction cup at the corresponding position, and the virtual reagent addition position means a position suspended in the air without support, and it is necessary to rely on the gripper in the reaction cup transfer module to hold the reaction cup and stay at the reagent addition position. The second position is the detection module (i.e., the detection position), and the detection module is used to detect the sample in the reaction cup. The reaction cup with added reagent is transferred from the reagent addition position to the detection module, and then detection is performed in the detection module. The detection module can be a magnetic bead method detection module, an optical detection module, or of course other detection modules. After adding reagents to the sample, in order to avoid taking too much time before reaching the detection module, mixing is performed during the process of transferring the sample with added reagent from the reagent addition position to the detection module, that is, mixing while transferring. Among them, the transfer operation and the mixing operation can be partially overlapped according to needs, and of course can also be completely overlapped. By performing the transfer and mixing in parallel to achieve the purpose of saving time, it is not only beneficial to improving the accuracy of the detection result, but also beneficial to improving the overall detection speed.

[0043] In one embodiment, the sample analyzer further includes: an incubation module, a reagent addition position, and a detection module; before the reaction cup transfer module is controlled to transfer the reaction cup from the first position to the second position and perform a mixing operation during the transfer from the first position to the second position, it further includes: controlling the reaction cup transfer module to place the reaction cup after adding the sample into the incubation module, and the incubation module is used to incubate the sample in the reaction cup; controlling the reaction cup transfer module to transfer the incubated reaction cup to the reagent addition position, and controlling the reagent needle to run to the reagent addition position to add the reagent; performing detection based on the mixed sample, including: controlling the detection module to perform sample detection based on the mixed sample.

[0044] Among them, the process of the sample analyzer performing sample detection includes: adding the sample into the reaction cup, then transferring the reaction cup with the added sample to the incubation module for incubation, then transferring the incubated sample to the reagent addition position to add the reagent, after adding the reagent, transferring the sample with the added reagent to the detection module, performing mixing during the transfer process, and then performing detection based on the mixed sample in the detection module. Applying the above sample analysis and detection method in the sample analyzer can not only improve the detection speed but also be beneficial to improving the accuracy of the detection results.

[0045] As Figure 2 shown, in one embodiment, controlling the reaction cup transfer module to transfer the reaction cup with the added reagent from the reagent addition position to the detection module and perform a mixing operation during the transfer to the detection module includes:

[0046] Step 202, obtain the preset mixing time corresponding to the test item to be tested, and determine the target moving speed of the reaction cup transfer module according to the preset mixing time.

[0047] Among them, the preset mixing time refers to the theoretical time required for performing the mixing operation in the test item. The preset mixing time can be preset according to the actual situation of each test item. In order to ensure that the mixing is completed or just completed before reaching the detection module, it is necessary to determine the target moving speed according to the preset mixing time. Generally, the distance from one position to another in the sample analyzer is fixed, so the target moving speed can be controlled to match the preset mixing time, so that the mixing is just completed or just completed when reaching the detection module and the liquid level in the reaction cup is calm or stable.

[0048] Step 204, control the reaction cup transfer module to transfer the reaction cup with the added reagent to the detection module at the target moving speed and perform a mixing operation during the transfer.

[0049] Among them, the target moving speed can be a speed calculated according to a preset mixing time. For example, given the moving distance, the target moving speed is calculated based on the moving distance and the preset mixing time. For instance, when the determined moving distance is 20 cm and the preset mixing time is 5 s, the target moving speed can be calculated by dividing the moving distance by the preset mixing time, resulting in 4 cm / s. The target moving speed can also be preset. For example, two transfer speeds can be preset, namely the first transfer speed and the second transfer speed, where the first transfer speed is greater than the second transfer speed. First, a preset transfer time needs to be set, and the target moving speed is determined by comparing the preset mixing time and the preset transfer time. When the preset mixing time is not greater than the preset transfer time, the first transfer speed is used as the target moving speed. When the preset mixing time is greater than the preset transfer time, the second transfer speed is used as the target moving speed. That is, only two speed gears need to be set. When the preset mixing time is relatively long, the low-speed gear is used for transfer. Conversely, when the preset mixing time is relatively short, the high-speed gear is used for transfer.

[0050] Determining the target moving speed according to the preset mixing time can ensure complete mixing before reaching the detection module, so that detection can be directly carried out after reaching the detection module. On the one hand, it is more conducive to saving time, and on the other hand, it can also make the detection result more accurate.

[0051] In one embodiment, determining the target moving speed of the reaction cup transfer module according to the preset mixing time includes: obtaining the preset moving time, which refers to the transfer time for the reaction cup transfer module to transfer the reaction cup from the reagent addition position to the position corresponding to the detection module at the preset transfer speed; when the preset mixing time is not greater than the preset transfer time, the preset transfer speed is used as the target moving speed; when the preset mixing time is greater than the preset transfer time, the target moving speed is calculated based on the preset mixing time and the transfer distance, and the transfer distance is the moving distance for the reaction cup transfer module to transfer the reaction cup from the reagent addition position to the position corresponding to the detection module.

[0052] Among them, the preset moving time refers to the preset transfer time from one position to another. The preset transfer speed refers to the preset moving speed when transferring from one position to another. The preset moving time and the preset transfer speed are corresponding, that is, the preset transfer time is the time required for transfer at the preset transfer speed. When the preset mixing time is not greater than the preset transfer time, it means that there is enough time for mixing during the transfer at the preset transfer speed. At this time, the preset transfer speed is directly used as the target transfer speed. When the preset mixing time is greater than the preset transfer time, it means that if the transfer is carried out at the preset transfer speed, there is not enough time for mixing. Therefore, it is necessary to re-determine the target transfer speed. The method for determining the target transfer speed is to calculate the target moving speed according to the preset mixing time and the transfer distance. There are various ways to calculate the target moving speed. Among them, one way is to calculate the average speed based on the transfer distance and the preset mixing time, and use the calculated average speed as the target moving speed. Another way is to preset two preset transfer speeds, namely the first preset speed and the second preset speed, and the first preset speed is greater than the second preset speed. When the average speed is greater than the first preset speed, the first preset speed is used as the target moving speed. When the translation speed is not greater than the first preset speed, the second preset speed is used as the target moving speed. It should be noted that the second preset speed is the preset minimum speed, and the calculated translation speed cannot be less than the second preset speed. Of course, multiple speed gears (more than two gears) can also be preset for selection according to needs. By determining the target moving speed, the purpose of saving the detection time and improving the detection accuracy is achieved by controlling the target moving speed.

[0053] In one embodiment, the reaction cup transfer module is controlled to transfer the reaction cup added with the reagent to the detection module at the target moving speed, and a mixing operation is performed during the transfer, including: when the preset mixing time is not greater than the preset transfer time, determining the mixing start position and the mixing end position; controlling the reaction cup transfer module to transfer at the target moving speed, starting the mixing operation when transferring to the mixing start position, and stopping the mixing operation when reaching the mixing end position.

[0054] Among them, in order to more accurately control the end time of mixing so that the mixing is just completed when reaching the detection module and the liquid level in the reaction cup returns to calm, when the preset mixing time is not greater than the preset transfer time, the mixing control can be performed by further determining the mixing start position and the mixing end position. For example, when the preset transfer time is 10 s and the preset mixing time is 6 s, the mixing end position can be set at the 9 s position, and then the corresponding mixing start position is set at the 4 s position, that is, the mixing starts at the 4 s from the start of transfer and ends at the 9 s position. By determining the mixing start position and the mixing end position, the mixing operation can be more precisely controlled, which is beneficial to subsequent more accurate detection and obtaining more real detection results. In one embodiment, the mixing end position is a position that has not reached the detection module to ensure that the liquid level of the mixed sample returns to calm when reaching the detection module.

[0055] In one embodiment, the reagent addition position is a virtual reagent addition position, and the virtual reagent addition position is located at a suspended position.

[0056] Among them, adopting the virtual reagent addition position for the reagent addition position is beneficial to saving occupied space. And compared with the physical reagent addition position (where the reaction cup needs to be placed at the physical addition position first, then the reagent is added, and after the reagent is added, the reaction cup needs to be grabbed and transferred to the detection module), the virtual addition position does not need to be grabbed and placed back and forth, which is beneficial to saving the detection time.

[0057] In one embodiment, the sample analyzer further includes: a virtual sample addition position; controlling the reaction cup transfer module to clamp the reaction cup and stay at the virtual sample addition position; controlling the sample addition needle to run to the virtual sample addition position to add the sample into the reaction cup.

[0058] Among them, adopting the virtual sample addition position for the sample addition position, compared with the physical sample addition position (where the reaction cup needs to be placed at the physical sample addition position first, then the sample is added, and after the sample is added, the reaction cup needs to be grabbed and transferred to the incubation module), the design of this virtual sample addition position is not only beneficial to saving space, but also beneficial to saving the detection time.

[0059] In one embodiment, the first position is the sample addition position, and the second position is the incubation module; during the detection process, controlling the reaction cup transfer module to transfer the reaction cup from the first position to the second position, and performing a mixing operation during the transfer from the first position to the second position, including: obtaining the item to be tested, when the item to be tested is a dilution type item, controlling the reaction cup after adding the diluent and the sample to be transferred to the incubation module, and performing a mixing operation during the transfer to the incubation module.

[0060] Among them, for dilution projects, while adding samples, diluent also needs to be added, and then the two are mixed. To save time, the reaction cups after adding diluent and samples are transferred to the incubation module in a way of mixing while transferring.

[0061] In one embodiment, the reaction cup transfer module includes: a motion mechanism and a mixing mechanism. The motion mechanism is used to grab and transfer the reaction cup, and the mixing mechanism performs a mixing operation on the samples and reagents in the reaction cup.

[0062] Among them, the motion mechanism is driven by a first motor and is used to grab and transfer the reaction cup. The mixing mechanism is driven by a second motor and is used to mix the samples and reagents in the reaction cup. In one embodiment, the motion mechanism is used to control the horizontal movement of the reaction cup, and the mixing mechanism is used to control the up and down movement of the reaction cup to achieve the purpose of mixing. The reaction cup transfer module is provided with both a motion mechanism and a mixing mechanism to achieve the purpose of mixing while transferring.

[0063] As Figure 3 shown, in one embodiment, a sample analyzer 300 is proposed, which includes: a reaction cup transfer module 302, a first position 304, and a second position 306; among them, the reaction cup transfer module is used to transfer the reaction cup from the first position to the second position, and a mixing operation is performed during the process of transferring from the first position to the second position, and detection is performed based on the mixed samples.

[0064] In one embodiment, the first position is the reagent addition position, and the second position is the detection module; the reaction cup transfer module is used to transfer the reaction cup after adding reagents from the reagent addition position to the detection module, and a mixing operation is performed during the process of transferring to the detection module.

[0065] As Figure 4 shown, it is a structural block diagram of a sample analyzer in one embodiment. In one embodiment, the sample analyzer further includes: an incubation module 308 and a controller 310; the incubation module 308 and the detection module (second position) 306 are arranged in sequence; the reaction cup transfer module is located above the incubation module and the detection module; the controller is connected to the incubation module, the detection module, and the reaction cup transfer module; among them, the reaction cup transfer module is used to transfer the incubated reaction cup to the reagent addition position (first position), and control the reagent needle to run to the reagent addition position to add reagents; after adding the reagents, the controller controls the reaction cup transfer module to transfer the reaction cup to the detection module, and a mixing operation is performed during the process of transferring to the detection module.

[0066] In one embodiment, the reaction cup transfer module includes: a motion mechanism and a mixing mechanism. The motion mechanism is used to grab the reaction cup and transfer it, and the mixing mechanism performs a mixing operation on the samples and reagents in the reaction cup.

[0067] In one embodiment, the reagent addition position is a virtual reagent addition position, and the virtual reagent addition position is located at a suspended position.

[0068] In one embodiment, the sample analyzer further includes: a virtual sample addition position, and the virtual sample addition position is arranged at a suspended position.

[0069] It can be understood that the above sample detection method and the sample analyzer belong to a general inventive concept, and the content in an embodiment of a sample detection method and a sample analyzer can be mutually applicable.

[0070] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. The program can be stored in a non-volatile computer-readable storage medium. When the program is executed, it can include the processes of the embodiments of the above methods. Among them, any reference to a memory, storage, database, or other medium used in the various embodiments provided in the present application can include non-volatile and / or volatile memories. Non-volatile memories can include read-only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM), or flash memory. Volatile memories can include random access memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in many forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double data rate SDRAM (DDR SDRAM), enhanced SDRAM (ESDRAM), synchronous link DRAM (SLDRAM), Rambus direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and Rambus dynamic RAM (RDRAM), etc.

[0071] The technical features of the above embodiments can be combined arbitrarily. For the sake of concise description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope described in this specification.

[0072] The above-described embodiments merely represent several implementation manners of the present application. The description thereof is relatively specific and detailed, but it should not be construed as a limitation on the patent scope of the present application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several modifications and improvements can still be made, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the appended claims.

Claims

1. A sample detection method, characterized in that, Applied to a sample analyzer, the sample analyzer includes: a reaction cup transfer module; The method includes: During the detection process, controlling the reaction cup transfer module to transfer the reaction cup from a first position to a second position, and performing a mixing operation during the transfer from the first position to the second position; Performing detection based on the mixed sample; The first position is a reagent addition position, and the second position is a detection module; controlling the reaction cup transfer module to transfer the reaction cup from the first position to the second position and performing a mixing operation during the transfer from the first position to the second position includes: controlling the reaction cup transfer module to transfer the reaction cup with added reagent from the reagent addition position to the detection module and performing a mixing operation during the transfer to the detection module; Controlling the reaction cup transfer module to transfer the reaction cup with added reagent from the reagent addition position to the detection module and performing a mixing operation during the transfer to the detection module includes: obtaining a preset mixing time corresponding to the item to be tested, and determining a target moving speed of the reaction cup transfer module according to the preset mixing time; controlling the reaction cup transfer module to transfer the reaction cup with added reagent to the detection module at the target moving speed and performing a mixing operation during the transfer; Determining the target moving speed of the reaction cup transfer module according to the preset mixing time includes: Obtaining a preset moving time, where the preset moving time refers to the transfer time when the reaction cup transfer module transfers the reaction cup from the reagent addition position to the detection module at a preset transfer speed; When the preset mixing time is not greater than the preset moving time, taking the preset transfer speed as the target moving speed; When the preset mixing time is greater than the preset moving time, calculating the target moving speed according to the preset mixing time and the transfer distance, where the transfer distance is the moving distance when the reaction cup transfer module transfers the reaction cup from the reagent addition position to the detection module.

2. The method according to claim 1, characterized in that The sample analyzer further includes: an incubation module, a reagent addition position, and a detection module; Before controlling the reaction cup transfer module to transfer the reaction cup from the first position to the second position and performing a mixing operation during the transfer from the first position to the second position, it further includes: Controlling the reaction cup transfer module to place the reaction cup with added sample into the incubation module, and the incubation module is used to incubate the sample in the reaction cup; Controlling the reaction cup transfer module to transfer the incubated reaction cup to the reagent addition position, and controlling the reagent needle to run to the reagent addition position to add reagent; Performing detection based on the mixed sample includes: Controlling the detection module to perform detection based on the mixed sample.

3. The method according to claim 1, wherein Controlling the reaction cup transfer module to transfer the reaction cup with added reagent to the detection module at the target moving speed and performing a mixing operation during the transfer includes: When the preset mixing time is not greater than the preset moving time, determining a mixing start position and a mixing end position; Control the reaction cup transfer module to transfer at a target moving speed, start the mixing operation when it is transferred to the mixing start position, and stop the mixing operation when it reaches the mixing end position.

4. The method according to claim 3, wherein The mixing end position is the position that has not reached the detection module, so as to ensure that the liquid level of the mixed sample returns to calm when it reaches the detection module.

5. The method according to any one of claims 1 to 4, characterized in that, The reagent addition position is a virtual reagent addition position, and the virtual reagent addition position is located at a suspended position.

6. The method according to claim 1, characterized in that, The sample analyzer further includes: a virtual sample addition position; The method further includes: Control the reaction cup transfer module to clamp the reaction cup and stay at the virtual sample addition position; Control the sample addition needle to run to the virtual sample addition position and add the sample to the reaction cup.

7. The method according to claim 1, wherein The first position is the sample addition position, and the second position is the incubation module; During the detection process, control the reaction cup transfer module to transfer the reaction cup from the first position to the second position, and perform a mixing operation during the transfer from the first position to the second position, including: Obtain the item to be tested. When the item to be tested is a dilution type item, control the reaction cup after adding the diluent and the sample to be transferred to the incubation module, and perform a mixing operation during the transfer to the incubation module.

8. The method according to claim 1, characterized in that, The reaction cup transfer module includes: a motion mechanism and a mixing mechanism. The motion mechanism is used to grab and transfer the reaction cup, and the mixing mechanism performs a mixing operation on the sample and reagent in the reaction cup.

9. A sample analyzer, applied to the sample detection method according to any one of claims 1-8, characterized in that, Including: A reaction cup transfer module, a first position, and a second position; Among them, use the reaction cup transfer module to transfer the reaction cup from the first position to the second position, perform a mixing operation during the transfer from the first position to the second position, and perform detection based on the mixed sample.

10. The sample analyzer according to claim 9, characterized in that, The first position is the reagent addition position, and the second position is the detection module; Use the reaction cup transfer module to transfer the reaction cup after adding the reagent from the reagent addition position to the detection module, and perform a mixing operation during the transfer to the detection module.

11. The sample analyzer according to claim 10, characterized in that, The sample analyzer further includes: an incubation module and a controller; The incubation module and the detection module are arranged in sequence; The reaction cup transfer module is located above the incubation module and the detection module; The controller is connected to the incubation module, the detection module, and the reaction cup transfer module; Among them, use the reaction cup transfer module to transfer the reaction cup after incubation to the reagent addition position, and control the reagent needle to run to the reagent addition position to add the reagent; After adding the reagent, the controller controls the reaction cup transfer module to transfer the reaction cup to the detection module, and perform a mixing operation during the transfer to the detection module.

12. The sample analyzer according to claim 9, characterized in that, The reaction cup transfer module includes: a motion mechanism and a mixing mechanism. The motion mechanism is used to grab and transfer the reaction cup, and the mixing mechanism performs a mixing operation on the sample and reagent in the reaction cup.

13. The sample analyzer according to claim 9, wherein, The reagent addition position is a virtual reagent addition position, and the virtual reagent addition position is located at a suspended position.

14. The sample analyzer according to claim 9, characterized in that, The sample analyzer further includes: a virtual sample addition position, and the virtual sample addition position is arranged at a suspended position.

Images