Cell dispensing refrigeration system and cell dispensing method

Abstract

The application relates to the technical field of cell dispensing, and provides a cell dispensing refrigeration system and a cell dispensing method.The cell dispensing refrigeration system comprises a control module, a refrigeration panel, a compressor, a temperature detection module, a liquid input module and a liquid output module, the refrigeration panel is used for mounting a liquid bag, the compressor is connected with the control module, the compressor is used for conveying refrigerant to the refrigeration panel, the temperature detection module is mounted on the refrigeration panel, the temperature detection module is connected with the control module, the temperature detection module is used for detecting the temperature of the liquid bag, so that the control module is adapted to adjust the power of the compressor according to the temperature of the liquid bag, the liquid input module is communicated with the liquid bag, and the liquid output module is communicated with the liquid bag.According to the cell dispensing refrigeration system provided by the application, the automatic cooling and dispensing of cell liquid are realized, the degree of automation of the system is improved, the automatic adjustment of the power of the compressor is realized, and the power consumption of the system is reduced.

Description

Technical Field

[0001] This application relates to the field of cell packaging technology, and in particular to cell packaging refrigeration systems and cell packaging methods. Background Technology

[0002] In the cell preparation process, cells need to be centrifuged, and then mixed with cryopreservation solution and dispensed for subsequent output. Cell dispensing equipment requires cryogenic storage of cells during dispensing to minimize cell toxicity during the dispensing process.

[0003] The cell dispensing equipment in related technologies has a low degree of automation, and in order to ensure the cooling effect, the refrigerator often operates at maximum power, resulting in high power consumption. Summary of the Invention

[0004] This application aims to address at least one of the technical problems existing in the related art. To this end, this application proposes a cell dispensing refrigeration system, which realizes automated cooling and dispensing of cell liquid, improves the automation level of the system, and can adjust the operating status of the compressor according to the temperature of the liquid bag, so that the power of the compressor changes with the temperature of the liquid bag, realizing automated adjustment of the compressor power, enabling the compressor to operate at optimal power, and reducing the power consumption of the system.

[0005] This application also proposes a cell dispensing method.

[0006] The cell dispensing refrigeration system according to an embodiment of this application includes:

[0007] Control module;

[0008] Refrigeration panel for mounting liquid bags;

[0009] A compressor, connected to the control module, is used to deliver refrigerant to the refrigeration panel to regulate the temperature of the liquid bag so that the temperature of the liquid bag is at a preset temperature value.

[0010] A temperature detection module is installed on the refrigeration panel and is connected to the control module. The temperature detection module is used to detect the temperature of the liquid bag, so that the control module is adapted to adjust the power of the compressor according to the temperature of the liquid bag.

[0011] A liquid input module is connected to the liquid bag, and the liquid input module is used to deliver the liquid to be processed into the liquid bag;

[0012] A liquid output module is connected to the liquid bag, and the liquid in the liquid bag is adapted to flow out through the liquid output module.

[0013] According to the cell dispensing and refrigeration system of this application embodiment, the liquid to be processed is delivered into the liquid bag through the liquid input module. The refrigeration panel cools the liquid in the liquid bag until the temperature of the liquid in the liquid bag reaches a preset value. Then, the liquid is output through the liquid output module for dispensing, thereby realizing automated cooling and dispensing of cell liquid and improving the automation level of the system. In addition, the temperature detection module detects the temperature of the liquid bag in real time and transmits the detection data to the control module. The control module adjusts the working power of the compressor according to the difference between the real-time temperature of the liquid bag and the preset temperature value. Thus, the operating state of the compressor can be adjusted according to the temperature of the liquid bag, so that the power of the compressor changes with the temperature of the liquid bag, realizing automated adjustment of the compressor power. The compressor can operate at the optimal power, reducing the power consumption of the system.

[0014] According to one embodiment of this application, the temperature detection module includes a temperature probe, which is mounted on the refrigeration panel and abuts against the outer wall of the liquid bag. The temperature probe is connected to the control module.

[0015] According to one embodiment of this application, the temperature detection module includes at least two temperature probes, which detect the temperature at different locations of the liquid bag.

[0016] According to one embodiment of this application, the cell dispensing refrigeration system includes a mixing module, which is mounted on the refrigeration panel and connected to the control module. The mixing module is used to mix the liquid in the liquid bag.

[0017] According to one embodiment of this application, the temperature probe is provided at the upper part, the middle part, and the lower part of the liquid bag, and the lower part of the liquid bag is located between the mixing module and the cooling panel.

[0018] According to one embodiment of this application, the cell dispensing refrigeration system includes an electronic valve, one end of which is connected to the compressor and the other end of which is connected to the refrigeration panel. The electronic valve is electrically or communicatively connected to the control module.

[0019] The cell dispensing method according to the second aspect of this application includes:

[0020] The liquid to be processed is transferred into the liquid bag;

[0021] Obtain the temperature and volume data of the liquid bag;

[0022] Start the compressor and keep it running at low power for a predetermined time to gradually deliver refrigerant to the refrigeration panel;

[0023] The temperature difference between the temperature of the liquid bag and the preset temperature value is determined, and the cooling power of the compressor is adjusted according to the temperature difference so that the liquid temperature in the liquid bag is reduced to the preset temperature value.

[0024] The liquid at the preset temperature value is output from the liquid bag and dispensed.

[0025] According to one embodiment of this application, obtaining the temperature data and volume data of the liquid bag includes:

[0026] The temperature at different locations on the liquid bag was obtained;

[0027] If the temperature difference between any two different locations in the liquid bag exceeds a first preset value, the liquid in the liquid bag will be mixed.

[0028] According to one embodiment of this application, mixing the liquid in the liquid bag includes:

[0029] The liquid in the lower part of the liquid bag is squeezed upwards, dividing the liquid bag into an upper part containing the solution and a lower part not containing the solution;

[0030] Temperature is detected at at least two locations on the upper part of the liquid bag containing the solution;

[0031] If the temperature difference between any two positions in the upper part is still greater than the first preset value, then continue mixing.

[0032] If the temperature difference between any two positions in the upper part is less than the first preset value, then stop mixing or continue mixing.

[0033] According to one embodiment of this application, determining the temperature difference between the temperature of the liquid bag and a preset temperature value, and adjusting the cooling power of the compressor based on the temperature difference, includes:

[0034] If the temperature difference is less than the second preset value, the compressor is controlled to be in a low-power state.

[0035] If the temperature difference is between the second preset value and the third preset value, the compressor is controlled to operate at half of its rated power, wherein the third preset value is greater than the second preset value;

[0036] If the temperature difference is greater than the third preset value, the compressor is controlled to operate at its rated power.

[0037] Additional aspects and advantages of this application will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of this application. Attached Figure Description

[0038] To more clearly illustrate the technical solutions in the embodiments or related technologies of this application, the accompanying drawings used in the description of the embodiments or related technologies will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0039] Figure 1 This is a schematic block diagram of the cell dispensing and refrigeration system provided in the embodiments of this application;

[0040] Figure 2 This is a schematic diagram of the structure of the refrigeration panel, liquid bag, and mixing module of the cell dispensing refrigeration system provided in the embodiments of this application;

[0041] Figure 3 This is a schematic diagram of the cell dispensing method provided in the embodiments of this application.

[0042] Figure label:

[0043] 1. Control module; 2. Refrigeration panel; 3. Liquid bag; 4. Compressor; 5. Temperature detection module;

[0044] 6. Liquid input module; 7. Liquid output module; 8. Mixing module; 81. Mixing plate. Detailed Implementation

[0045] The embodiments of this application will be described in further detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this application, but should not be used to limit the scope of this application.

[0046] In the description of the embodiments of this application, it should be noted that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the embodiments of this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this application. In addition, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0047] In the description of the embodiments of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "connected" and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of this application based on the specific circumstances.

[0048] In the embodiments of this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0049] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the embodiments of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0050] The following is combined with Figures 1 to 3 This application describes the cell dispensing refrigeration system and cell dispensing method.

[0051] According to the embodiments of the first aspect of this application, such as Figure 1 and Figure 2As shown, the cell dispensing refrigeration system includes a control module 1, a refrigeration panel 2, a compressor 4, a temperature detection module 5, a liquid input module 6, and a liquid output module 7. The refrigeration panel 2 is used to install a liquid bag 3. The compressor 4 is connected to the control module 1 and is used to supply refrigerant to the refrigeration panel 2 to regulate the temperature of the liquid bag 3 so that the temperature of the liquid bag 3 is at a preset temperature value. The temperature detection module 5 is installed on the refrigeration panel 2 and is connected to the control module 1. The temperature detection module 5 is used to detect the temperature of the liquid bag 3, so that the control module 1 can adjust the power of the compressor 4 according to the temperature of the liquid bag 3. The liquid input module 6 is connected to the liquid bag 3 and is used to deliver the liquid to be processed into the liquid bag 3. The liquid output module 7 is connected to the liquid bag 3, and the liquid in the liquid bag 3 is suitable for flowing out through the liquid output module 7.

[0052] In operation, control module 1 starts compressor 4 and initially operates it at low power, allowing it to slowly deliver refrigerant to the refrigerant pipes of the refrigeration panel 2. This enables the mechanical structure to adapt to temperature changes. Compared to related technologies that directly and rapidly deliver refrigerant to the refrigeration panel 2 upon system startup, this application effectively improves the system's lifespan. The liquid to be processed is delivered to the liquid bag 3 via liquid input module 6, and the temperature of the liquid bag 3 is detected by temperature detection module 5 to obtain its initial temperature. Control module 1 then automatically adjusts the power of compressor 4 based on the initial temperature of the liquid bag 3 to regulate the temperature of the liquid within it. Temperature detection module 5 continuously monitors the temperature of liquid bag 3 and transmits the real-time temperature to control module 1. Control module 1 compares the real-time temperature of liquid bag 3 with a preset temperature value, ensuring that the operating power of compressor 4 is proportional to the difference between the real-time temperature of liquid bag 3 and the preset temperature value. That is, the greater the difference between the real-time temperature of liquid bag 3 and the preset temperature value, the higher the operating power of compressor 4. Therefore, the operating power of compressor 4 can be adjusted based on the real-time temperature of liquid bag 3. When the temperature of the liquid inside liquid bag 3 reaches the preset value, the liquid inside liquid bag 3 is output through liquid output module 7, which can control the amount of liquid output, thus performing liquid dispensing. This achieves automated cooling and dispensing of cell fluid, improving the system's automation level. The operating status of compressor 4 can be adjusted according to the temperature of liquid bag 3, causing the power of compressor 4 to change with the temperature of liquid bag 3, achieving automated power adjustment of compressor 4. Compressor 4 can operate at optimal power, reducing system power consumption.

[0053] The cell dispensing refrigeration system of this application embodiment delivers the liquid to be processed into the liquid bag 3 through the liquid input module 6. The refrigeration panel 2 cools the liquid in the liquid bag 3 until the temperature of the liquid in the liquid bag 3 reaches a preset value. Then, the liquid is output through the liquid output module 7 for dispensing, thereby realizing automated cooling and dispensing of cell liquid and improving the automation level of the system. In addition, the temperature detection module 5 detects the temperature of the liquid bag 3 in real time and transmits the detection data to the control module 1. The control module 1 adjusts the working power of the compressor 4 according to the difference between the real-time temperature of the liquid bag 3 and the preset temperature value. Thus, the operating state of the compressor 4 can be adjusted according to the temperature of the liquid bag 3, so that the power of the compressor 4 changes with the temperature of the liquid bag 3. This realizes the automated adjustment of the power of the compressor 4, and the compressor 4 can operate at the optimal power, reducing the power consumption of the system.

[0054] In the embodiments of this application, the connection between the compressor 4 and the control module 1, and the connection between the temperature detection module 5 and the control module 1, can be either an electrical connection or a communication connection.

[0055] In the embodiments of this application, the control module 1 is equipped with a PID temperature control program, which enables the control module 1 to immediately detect the current temperature of the liquid bag 3 after obtaining the input set target temperature. When the temperature of the liquid bag 3 is lower than the target temperature, the compressor 4 will be started. However, when the temperature of the liquid bag 3 is close to the target temperature, the power of the compressor 4 will be controlled at a low power state to allow the temperature of the liquid bag 3 to gradually approach the target temperature. When the temperature of the liquid bag 3 exceeds the set temperature, the compressor 4 will be turned off.

[0056] In the embodiments of this application, the control module 1 is, for example, a compressor driver. However, it should be understood that the control module 1 can also be any other suitable component with control functions.

[0057] In one embodiment of this application, a hook is provided on the cooling panel 2, and a through hole matching the hook is provided at the upper end of the liquid bag 3. In use, the hook is passed through the through hole of the liquid bag 3, so that the liquid bag 3 can be hung on the cooling panel 2, thereby facilitating temperature detection and temperature adjustment of the liquid bag 3.

[0058] In one embodiment of this application, the temperature detection module 5 includes a temperature probe mounted on the refrigeration panel 2, abutting against the outer wall of the liquid bag 3, and connected to the control module 1. In use, the temperature probe is mounted on the refrigeration panel 2 and brought into contact with the outer wall of the liquid bag 3, allowing the probe to detect the temperature of the liquid bag 3 without contacting the liquid inside. This enables non-contact temperature data acquisition. The temperature probe then transmits the detected temperature data to the control module 1, allowing the control module 1 to control the operating power of the compressor 4 based on the real-time temperature of the liquid bag 3, thereby maintaining the temperature of the liquid bag 3 at a preset value.

[0059] In one embodiment of this application, the temperature detection module 5 includes at least two temperature probes, which detect the temperature at different locations on the liquid bag 3. In use, by setting at least two temperature probes on the cooling panel 2 to detect the temperature at different locations on the liquid bag 3, temperature data at different locations on the liquid bag 3 can be obtained, allowing for a more accurate determination of the real-time temperature of the liquid bag 3. Furthermore, even if one temperature probe malfunctions, the other temperature probes can still detect the temperature of the liquid bag 3.

[0060] In one embodiment of this application, such as Figure 1 and Figure 2 As shown, the cell dispensing and refrigeration system includes a mixing module 8, which is mounted on the refrigeration panel 2 and connected to the control module 1. The mixing module 8 is used to mix the liquid in the liquid bag 3. During use, two or more temperature probes simultaneously detect the temperature at different locations on the liquid bag 3. When the temperature difference between any two locations on the liquid bag 3 exceeds a preset value, the control module 1 sends a corresponding signal to the mixing module 8, which then starts working. The mixing module 8 mixes the liquid in the liquid bag 3, ensuring that the liquid is mixed together and that the temperature at different locations on the liquid bag 3 remains consistent.

[0061] In the embodiments of this application, when the temperature difference between any two locations of the liquid bag 3 exceeds, for example, a first preset value, the mixing module 8 will begin to mix the liquid in the liquid bag 3.

[0062] In the embodiments of this application, such as Figure 1 and Figure 2As shown, the mixing module 8 includes a mixing plate 81, which is mounted on the cooling panel 2. The liquid bag 3 is located between the mixing plate 81 and the cooling panel 2. The mixing plate 81 can reciprocate relative to the cooling panel 2. In use, the reciprocating movement of the mixing plate 81 relative to the cooling panel 2 is controlled, so that the mixing plate 81 moves closer to or further away from the cooling panel 2. When the mixing plate 81 moves closer to the cooling panel 2, it squeezes the liquid bag 3, thereby squeezing the liquid in the liquid bag 3 and mixing the liquids together, thus achieving the mixing operation of the liquid bag 3.

[0063] Specifically, the lower part of the liquid bag 3 is located between the mixing plate 81 and the cooling plate 2, that is, the mixing plate 81 can squeeze the lower part of the liquid bag 3, squeezing the liquid in the lower part of the liquid bag 3 upward, so that the liquid in the liquid bag 3 is mixed together.

[0064] In one embodiment of this application, such as Figure 1 As shown, temperature probes are installed at the top, middle, and bottom of the liquid bag 3. The bottom of the liquid bag 3 is located between the mixing module 8 and the cooling panel 2. During operation, new liquid to be processed flows into the liquid bag 3, and liquid also flows out. The flow of liquid in the liquid bag 3 causes temperature changes. When the temperature difference between any two locations in the liquid bag 3 exceeds a preset value, the mixing module 8 is activated. The mixing module 8 squeezes the liquid at the bottom of the liquid bag 3 upwards, mixing the liquids together. Before the mixing module 8 squeezes the lower part of the liquid bag 3, the temperature probes at the upper and middle parts of the liquid bag 3 do not work temporarily, that is, the temperature of the upper and middle parts of the liquid bag 3 is not detected temporarily. This is because as the liquid flows out, there may be no liquid in the upper and middle parts of the liquid bag 3 at this time, thus avoiding the detection of temperature data that does not match the liquid temperature. When the mixing module 8 squeezes the liquid bag 3, the temperature probes at the upper and middle parts of the liquid bag 3 start to detect the temperature of the liquid bag 3, ensuring the accuracy of temperature detection.

[0065] Specifically, a temperature probe can also be installed at the outlet of liquid bag 3 or any other suitable location to further improve the comprehensiveness and accuracy of temperature detection of liquid bag 3.

[0066] In one embodiment of this application, the cell dispensing refrigeration system includes an electronic valve. One end of the electronic valve is connected to the compressor 4, and the other end is connected to the refrigeration panel 2. The electronic valve is electrically or communicatively connected to the control module 1. In use, one end of the electronic valve is connected to the compressor 4 via a pipe, and the other end is connected to the refrigeration panel 2, so that the refrigerant delivered from the compressor 4 to the refrigeration panel 2 must pass through the electronic valve. The temperature detection module 5 detects the actual temperature of the liquid bag 3 and transmits the detection data to the control module 1. Based on the comparison between the actual temperature of the liquid bag 3 and the preset temperature, the control module 1 adjusts the operating power of the compressor 4 and the opening degree of the electronic valve according to the temperature difference between the actual temperature of the liquid bag 3 and the preset temperature. This ensures that the operating power of the compressor 4 and the opening degree of the electronic valve are proportional to the magnitude of the temperature difference, thereby achieving the optimal refrigeration effect, avoiding prolonged operation at maximum power, and reducing the system's power consumption.

[0067] In one embodiment of this application, the liquid input module 6 includes a first peristaltic pump, one end of which is connected to the inlet of the liquid bag 3, and the other end of which is connected to the liquid to be processed. In use, the first peristaltic pump can deliver the liquid to be processed into the liquid bag 3, achieving automatic delivery of the liquid and improving the automation level of the system.

[0068] In one embodiment of this application, the liquid output module 7 includes a second peristaltic pump, one end of which is connected to the liquid bag 3, and the other end of which is connected to the outlet of the liquid bag 3. In use, the second peristaltic pump can transport the liquid in the liquid bag 3 to a dispensing container or other components, achieving automatic outflow of liquid from the liquid bag 3 and improving the system's automation level.

[0069] According to an embodiment of the second aspect of this application, such as Figure 3 As shown, the cell dispensing method includes:

[0070] 101. Transfer the liquid to be processed into liquid bag 3;

[0071] Specifically, the liquid to be processed is automatically transported into the liquid bag 3 through the liquid input module 6, such as the peristaltic pump, which improves the automation level of the system.

[0072] 102. Obtain the temperature and volume data of liquid bag 3;

[0073] Specifically, the temperature of the liquid bag 3 is detected by the temperature detection module 5 to obtain the temperature data of the liquid bag 3. Measurement is performed when the peristaltic pump delivers the liquid to be processed into the liquid bag 3 to obtain the volume data of the liquid bag 3. Alternatively, the weight of the liquid bag 3 can be detected, and the volume data of the liquid bag 3 can be obtained based on the density of the liquid. Other suitable methods can also be used to obtain the volume data of the liquid bag 3, which will not be described in detail here.

[0074] 103. Start compressor 4 and keep compressor 4 running at low power for a predetermined time to gradually deliver refrigerant to refrigeration panel 2;

[0075] Specifically, when starting compressor 4, in order to better control the overall power, the machine adopts a slow start method. When starting the cell dispensing refrigeration system, the system will keep compressor 4 in a low power and low speed working state for four to six minutes. This state is to allow the refrigerant to slowly enter the refrigeration pipe of the refrigeration panel 2, so that the refrigeration panel 2 is in a slow temperature change state, giving the mechanical structure time to adapt, which can increase the service life of the system.

[0076] Furthermore, when compressor 4 is started, it operates at low power for five minutes to gradually deliver refrigerant to the cooling panel 2. At this time, the power of compressor 4 is less than half of its rated power. In this embodiment, the power of compressor 4 is less than 150W.

[0077] 104. Determine the temperature difference between the temperature of liquid bag 3 and the preset temperature value, and adjust the cooling power of compressor 4 according to the temperature difference so that the liquid temperature in liquid bag 3 is reduced to the preset temperature value.

[0078] Specifically, the operating power of compressor 4 is adjusted according to the temperature difference, so that the operating power of compressor 4 is proportional to the size of the temperature difference. That is, the greater the difference between the temperature of liquid bag 3 and the preset temperature value, the higher the operating power of compressor 4. Thus, the operating power of compressor 4 can be adjusted according to the temperature of liquid bag 3, so that the power of compressor 4 changes with the temperature of liquid bag 3, realizing the automatic adjustment of the power of compressor 4. Compressor 4 can operate at the optimal power, reducing the power consumption of the system.

[0079] 105. The liquid at the preset temperature is output from the liquid bag 3 and dispensed.

[0080] Specifically, the liquid output module 7, such as the peristaltic pump, outputs the refrigerated liquid at a preset temperature from the liquid bag 3 and performs dispensing, thereby realizing automated cooling and dispensing of cell fluid and improving the automation level of the system.

[0081] In one embodiment of this application, obtaining temperature and volume data of the liquid bag 3 specifically includes:

[0082] The temperature at different locations in liquid bag 3 was obtained;

[0083] If the temperature difference between any two different locations in the liquid bag 3 exceeds a first preset value, the liquid inside the liquid bag 3 is mixed. During use, at least two temperature probes are installed on the cooling panel 2 to detect the temperature at different locations in the liquid bag 3, thereby obtaining temperature data for different locations in the liquid bag 3. When the temperature difference between any two locations in the liquid bag 3 exceeds the first preset value, a mixing operation is performed on the liquid bag 3 to mix the liquid inside, thus ensuring that the temperature at different locations in the liquid bag 3 remains consistent.

[0084] In the embodiments of this application, the first preset value is, for example, 2 degrees Celsius. However, it should be understood that the first preset value can also be any other suitable value, and the value of the first preset value can be increased or decreased according to the actual situation.

[0085] In one embodiment of this application, the liquid in the mixing bag 3 specifically includes:

[0086] Squeeze the liquid in the lower part of the liquid bag 3 upwards to divide the liquid bag 3 into an upper part containing the solution and a lower part not containing the solution;

[0087] Temperature is detected at at least two locations on the upper part of the liquid bag 3 containing the solution;

[0088] If the temperature difference between any two positions in the upper part is still greater than the first preset value, then continue mixing.

[0089] If the temperature difference between any two positions in the upper part is less than the first preset value, then stop mixing or continue mixing.

[0090] During use, as liquid flows into or out of liquid bag 3, the temperature inside liquid bag 3 changes. When the temperature difference between any two locations in liquid bag 3 exceeds a preset value, liquid bag 3 is squeezed to mix the liquid. Before squeezing liquid bag 3, temperature detection of the middle and upper parts of liquid bag 3 is paused because, as liquid flows out, the upper and middle parts of liquid bag 3 may be empty, thus avoiding discrepancies between the detected temperature data and the liquid temperature. When liquid bag 3 is squeezed, the liquid at the bottom of liquid bag 3 is forced to the upper middle part, dividing liquid bag 3 into an upper part containing solution and a lower part without solution. The temperature of the part containing solution is then detected to ensure accuracy. If the temperature difference between any two locations in the upper part containing solution is still greater than the first preset value, further mixing is required, and the squeezing and mixing operation of liquid bag 3 continues. If the temperature difference between any two locations in the upper part containing solution is less than the first preset value, the mixing operation can be stopped or continued to ensure thorough mixing of the liquid inside liquid bag 3.

[0091] In one embodiment of this application, determining the temperature difference between the temperature of the liquid bag 3 and a preset temperature value, and adjusting the cooling power of the compressor 4 according to the temperature difference, specifically includes:

[0092] If the temperature difference is less than the second preset value, the compressor 4 is controlled to be in a low-power state.

[0093] If the temperature difference is between the second preset value and the third preset value, the compressor 4 is controlled to operate at half of its rated power, wherein the third preset value is greater than the second preset value;

[0094] If the temperature difference is greater than the third preset value, control the compressor 4 to operate at rated power.

[0095] During use, the temperature detection module 5 detects the temperature of the liquid bag 3 and compares it with a preset temperature value. Based on the temperature difference between the liquid bag 3 and the preset temperature value, the operating power of the compressor 4 is controlled. This allows the compressor 4 to adjust its operating state in real time according to the preset temperature value, ensuring it operates at its optimal power and avoiding prolonged high-power operation, thus reducing power consumption. When the temperature difference is large, it automatically operates at maximum power, ensuring that the liquid in the liquid bag 3 reaches the preset temperature value within a preset time, even with varying quantities and initial temperatures.

[0096] In the embodiments of this application, the second preset value is, for example, 5 degrees Celsius, and the third preset value is, for example, 10 degrees Celsius. However, it should be understood that the second and third preset values ​​can also be any other suitable values. The second and third preset values ​​can be increased or decreased according to actual needs, as long as the third preset value is greater than the second preset value.

[0097] In one embodiment of this application, the cell dispensing method includes: determining whether the liquid in the liquid bag 3 is less than 0.5 mL; if so, stopping the acquisition of temperature data for the liquid bag 3. In use, by comparing the amount of liquid input into the liquid bag 3 with the amount of liquid output from the liquid bag 3, the amount of liquid remaining in the liquid bag 3 can be determined. When the liquid in the liquid bag 3 is less than 0.5 mL, the acquisition of temperature data for the liquid bag 3 is stopped to avoid inaccurate temperature data.

[0098] Finally, it should be noted that the above embodiments are only used to illustrate this application and are not intended to limit this application. Although this application has been described in detail with reference to the embodiments, those skilled in the art should understand that various combinations, modifications, or equivalent substitutions of the technical solutions of this application do not depart from the spirit and scope of the technical solutions of this application and should be covered within the scope of the claims of this application.

Claims

1. A cell dispensing method, applied to a cell dispensing refrigeration system, the cell dispensing refrigeration system comprising: Control module; Refrigeration panel for mounting liquid bags; A compressor, connected to the control module, is used to deliver refrigerant to the refrigeration panel to regulate the temperature of the liquid bag so that the temperature of the liquid bag is at a preset temperature value. A temperature detection module is installed on the refrigeration panel and is connected to the control module. The temperature detection module is used to detect the temperature of the liquid bag, so that the control module is adapted to adjust the power of the compressor according to the temperature of the liquid bag. A liquid input module is connected to the liquid bag, and the liquid input module is used to deliver the liquid to be processed into the liquid bag; A liquid output module is connected to the liquid bag, and the liquid in the liquid bag is adapted to flow out through the liquid output module; The cell dispensing method includes: The liquid to be processed is transferred into the liquid bag; Obtain the temperature and volume data of the liquid bag; Start the compressor and keep it running at low power for a predetermined time to gradually deliver refrigerant to the refrigeration panel; The temperature difference between the temperature of the liquid bag and the preset temperature value is determined, and the cooling power of the compressor is adjusted according to the temperature difference so that the liquid temperature in the liquid bag is reduced to the preset temperature value. The liquid at the preset temperature value is output from the liquid bag and dispensed. The acquisition of the temperature and volume data of the liquid bag includes: The temperature at different locations on the liquid bag was obtained; If the temperature difference between any two different locations in the liquid bag exceeds a first preset value, the liquid in the liquid bag will be mixed.

2. The cell partitioning method of claim 1, wherein, The temperature detection module includes a temperature probe, which is mounted on the refrigeration panel and abuts against the outer wall of the liquid bag. The temperature probe is connected to the control module.

3. The cell partitioning method of claim 2, wherein, The temperature detection module includes at least two temperature probes, which detect the temperature at different locations on the liquid bag.

4. The cell partitioning method of claim 3, wherein, The cell dispensing and refrigeration system includes a mixing module, which is mounted on the refrigeration panel and connected to the control module. The mixing module is used to mix the liquid in the liquid bag.

5. The cell partitioning method of claim 4, wherein, The temperature probes are provided at the upper part, middle part, and lower part of the liquid bag, with the lower part of the liquid bag located between the mixing module and the cooling panel.

6. The cell aliquoting method according to any one of claims 1 to 5, wherein, The cell dispensing refrigeration system includes an electronic valve, one end of which is connected to the compressor and the other end of which is connected to the refrigeration panel. The electronic valve is electrically or communicatively connected to the control module.

7. The cell subdivision method of claim 1, wherein, The mixing of the liquid in the liquid bag includes: The liquid in the lower part of the liquid bag is squeezed upwards, dividing the liquid bag into an upper part containing the solution and a lower part not containing the solution; Temperature is detected at at least two locations on the upper part of the liquid bag containing the solution; If the temperature difference between any two positions in the upper part is still greater than the first preset value, then continue mixing. If the temperature difference between any two positions in the upper part is less than the first preset value, then stop mixing or continue mixing.

8. The cell dispensing method according to claim 1, characterized in that, The step of determining the temperature difference between the temperature of the liquid bag and a preset temperature value, and adjusting the cooling power of the compressor based on the temperature difference, includes: If the temperature difference is less than the second preset value, the compressor is controlled to be in a low-power state. If the temperature difference is between the second preset value and the third preset value, the compressor is controlled to operate at half of its rated power, wherein the third preset value is greater than the second preset value; If the temperature difference is greater than the third preset value, the compressor is controlled to operate at its rated power.

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