Thrombectomy Device

Abstract

The present invention relates to the field of medical equipment, and provides a thrombus removal device, which comprises a conveying assembly and a thrombus removal bracket, wherein the conveying assembly comprises an end, an inner tube, an intermediate tube, an outer tube and a suction catheter, wherein the end is connected to one end of the inner tube, the intermediate tube is movably sleeved with the inner tube, the outer tube is movably sleeved with the intermediate tube, a drug spraying hole is provided on the tube wall of the outer tube, the outer tube is suitable for conveying thrombolytic drugs to be sprayed from the drug spraying hole, the suction catheter is movably sleeved with the outer tube, and the suction catheter is suitable for aspirating thrombus; one end of the thrombus removal bracket is connected to the end, and the other end is connected to one end of the intermediate tube adjacent to the end, the thrombus removal bracket is sleeved on the outside of the inner tube and the intermediate tube, and the thrombus removal bracket moves with the inner tube and the intermediate tube to be exposed outside the outer tube or received inside the outer tube. The present invention improves the thrombus removal effect and efficiency through a combination of thrombolysis and mechanical thrombus removal.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a thrombus removal device. Background Art

[0002] Venous thromboembolism (VTE) includes pulmonary thromboembolism (PE) and deep vein thrombosis (DVT). PE and DVT have the same risk factors, and more than 95% of emboli originate from the lower limbs. They are two clinical manifestations of VTE in different parts and stages. PE is the third leading cause of death after coronary heart disease and stroke. It is characterized by high incidence, high disability rate and high mortality rate. It is a severe and emergency disease of the respiratory system. However, there are relatively few new technologies aimed at reducing the incidence and mortality of PE.

[0003] At present, common treatments for pulmonary embolism include anticoagulation, thrombolysis, mechanical thrombectomy and other treatment methods. Among the related technologies, mechanical thrombectomy is mainly achieved through dissolution, crushing, suction, stent or basket thrombectomy, and is currently the main clinical treatment method. The current thrombectomy method is mainly to embed a thrombectomy stent into the thrombus, and then drag the thrombus into the suction catheter to achieve the purpose of thrombus capture and suction removal. The method of capturing thrombi with a thrombectomy stent and removing them by suction with a suction catheter is generally safe and effective, but because the thrombus often needs to be cut and grasped during the thrombus removal process, some broken thrombi will be missed, and for large thrombi, incomplete thrombus removal is prone to occur. Summary of the invention

[0004] The present invention aims to solve at least one of the technical problems existing in the related art. To this end, the present invention proposes a thrombus removal device, which aims to combine thrombolysis through a spray hole and mechanical thrombus removal, thereby improving the thrombus removal effect and efficiency.

[0005] The thrombus removal device according to the first embodiment of the present invention comprises:

[0006] A delivery assembly, the delivery assembly comprises an end cap, an inner tube, an intermediate tube, an outer tube and a suction catheter, the end cap is connected to one end of the inner tube, the intermediate tube is movably sleeved on the inner tube, the outer tube is movably sleeved on the intermediate tube, a spray hole is provided on the tube wall of the outer tube, the outer tube is suitable for delivering thrombolytic drugs to be sprayed from the spray hole, the suction catheter is movably sleeved on the outer tube, and the suction catheter is suitable for suctioning thrombus;

[0007] A thrombus removal bracket, one end of which is connected to the end head, and the other end is connected to an end of the middle tube adjacent to the end head. The thrombus removal bracket is sleeved on the outside of the inner tube and the middle tube, and the thrombus removal bracket moves with the inner tube and the middle tube to be exposed outside the outer tube or accommodated inside the outer tube.

[0008] According to the thrombus removal device of the embodiment of the present invention, the inner tube, the middle tube and the outer tube part that are movably sleeved in sequence are passed through the thrombus through the end, so that the spray hole on the outer tube corresponds to the thrombus. In this way, by injecting thrombolytic drugs into the outer tube, the thrombus is pre-treated first and part of the thrombus is dissolved. At the same time, the middle tube and the inner tube inside the outer tube are movable. After the outer tube passes through the thrombus and injects thrombolytic drugs to pre-treat the thrombus, the middle tube and the inner tube extend out, thereby driving the thrombus removal bracket to appear outside the outer tube, and moving the outer tube toward the tube mouth of the suction catheter, so that the thrombus removal bracket drives the thrombus to the suction catheter for suction, thereby achieving the removal of the thrombus. Through the combination of thrombolysis and mechanical thrombectomy, the thrombus removal effect and efficiency are improved.

[0009] According to one embodiment of the present invention, a storage section is provided at one end of the outer tube adjacent to the end head, and the thrombus removal bracket can be stored in the storage section. The outer tube is also provided with a spraying section, and the spraying section is arranged adjacent to the storage section. The spraying section is located at an end of the storage section away from the end head, and the spraying hole is arranged in the spraying section.

[0010] According to one embodiment of the present invention, there are multiple spray holes, and the multiple spray holes are evenly distributed along the circumference of the spray section.

[0011] According to one embodiment of the present invention, the thrombus removal stent comprises:

[0012] A body, wherein the body is sleeved on the inner tube and the middle tube, one end of the body is connected to the end head, and the other end of the body is connected to an end of the middle tube adjacent to the end head;

[0013] A net disk, the net disk being arranged at one end of the body adjacent to the end head;

[0014] At least two net bags, which are arranged on the body and located on the side of the net plate facing away from the end head, with a predetermined distance between adjacent net bags, and at least two net bags having the same or different diameters;

[0015] Wherein, the diameter of the net disk is greater than the diameter of the net bag.

[0016] According to an embodiment of the present invention, the mesh disk is curved in an arc shape in a direction away from the end head.

[0017] According to one embodiment of the present invention, the mesh disk is provided with a coating.

[0018] According to one embodiment of the present invention, the net bag comprises a first section and a second section connected in a direction away from the end head, and the taper of the first section of part or all of the net bag is the same as or different from the taper of the second section.

[0019] According to one embodiment of the present invention, the thrombus removal bracket also includes a plurality of mesh disks, all of which are located on the side of the net bag facing the end head, with a spacing between two adjacent mesh disks, and a diameter of the mesh disk adjacent to the end head is larger than a diameter of the other mesh disks.

[0020] According to an embodiment of the present invention, the mesh disk and the mesh bag are both woven from silk materials, and the weaving density of the mesh disk is greater than that of the mesh bag.

[0021] According to one embodiment of the present invention, the wire diameter of the net disk is smaller than the wire diameter of the net bag.

[0022] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or related technologies, the drawings required for use in the embodiments or related technical descriptions are briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0024] Figure 1 is a schematic structural diagram of a thrombus removal device provided by an embodiment of the present invention;

[0025] Figure 2 is a perspective structural diagram of the thrombus removal device provided by an embodiment of the present invention when the thrombus removal bracket is released;

[0026] Figure 3 is a schematic diagram of the structure of the thrombus removal device provided by an embodiment of the present invention when the thrombus removal bracket is stored;

[0027] Figure 4 It is a partial structural schematic diagram of an outer tube in a thrombus removal device provided in an embodiment of the present invention;

[0028] Figure 5 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in an embodiment of the present invention;

[0029] Figure 6 is a front view of a first mesh disk in the thrombus removal device provided by an embodiment of the present invention;

[0030] Figure 7 is a front view of a first net bag in the thrombus removal device provided by an embodiment of the present invention;

[0031] Figure 8 is a schematic structural diagram of a first network disk in the thrombus removal device provided in an embodiment of the present invention;

[0032] Fig. 9 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in another embodiment of the present invention;

[0033] Fig.10 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in another embodiment of the present invention;

[0034] Fig.11 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in yet another embodiment of the present invention;

[0035] Fig.12 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in yet another embodiment of the present invention;

[0036] Fig.13 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in yet another embodiment of the present invention;

[0037] Fig.14 is a schematic structural diagram of a thrombus removal bracket in a thrombus removal device provided in yet another embodiment of the present invention;

[0038] Fig.15 is a schematic structural diagram of a thrombus removal process of a thrombus removal device provided by an embodiment of the present invention;

[0039] Fig.16 is a schematic structural diagram of a thrombus removal process of a thrombus removal device provided by an embodiment of the present invention;

[0040] Fig.17 4 is a schematic structural diagram of the thrombus removal process of the thrombus removal device provided in an embodiment of the present invention.

[0041] Reference numerals:

[0042] 100. Thrombectomy device; 1. Thrombectomy bracket; 10. Main body; 11. First mesh disk; 111. Coating; 12. First mesh bag; 121. First section; 122. Second section; 13. Second mesh bag; 131. Third section; 132. Fourth section; 14. Second mesh disk; 15. Third mesh bag; 21. End; 22. Inner tube; 23. Middle tube; 24. Outer tube; 241. Spray hole; 242. Storage section; 243. Spray section; 25. Suction catheter; 26. First developing device; 27. Second developing device; 200. Thrombus. DETAILED DESCRIPTION

[0043] The following embodiments of the present invention are described in further detail in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0044] In the description of the embodiments of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the embodiments of the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limitations on the embodiments of the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0045] In the description of the embodiments of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific circumstances.

[0046] In the embodiments of the present invention, unless otherwise clearly specified and limited, the first feature being "above" or "below" the second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0047] The term "proximal end" generally refers to the end of the corresponding component closer to the operator, and the term "distal end" refers to the end of the corresponding component farther from the operator.

[0048] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the embodiment of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0049] Please refer to Figures 1 to 4 According to the first embodiment of the present invention, the thrombus removal device 100 includes a conveying component and a thrombus removal bracket 1. The conveying component includes an end 21, an inner tube 22, an intermediate tube 23, an outer tube 24 and a suction catheter 25. The end 21 is connected to one end of the inner tube 22. The intermediate tube 23 is movably mounted on the inner tube 22. The outer tube 24 is movably mounted on the intermediate tube 23. A spray hole 241 is provided on the tube wall of the outer tube 24. The outer tube 24 is suitable for conveying thrombolytic drugs to be sprayed from the spray hole 241. The suction catheter 25 is movably mounted on the outer tube 24. The suction catheter 25 is suitable for aspirating thrombus 200. One end of the thrombus removal bracket 1 is connected to the end 21, and the other end is connected to one end of the intermediate tube 23 adjacent to the end 21. The thrombus removal bracket 1 is mounted on the outside of the inner tube 22 and the intermediate tube 23. The thrombus removal bracket 1 moves with the inner tube 22 and the intermediate tube 23 to be exposed outside the outer tube 24 or stored inside the outer tube 24.

[0050] In this embodiment, the inner tube 22, the middle tube 23, the outer tube 24 and the suction catheter 25 are movably connected from the inside to the outside, and the end 21 is connected to one end of the inner tube 22. According to one embodiment of the present invention, the end 21 is in a cone shape. The end 21 is used to pass through the thrombus 200 during the advancement process to facilitate advancement, so that the spraying hole 241 on the outer tube 24 sprays the thrombus 200. It can be understood that there is a gap between the middle tube 23 and the outer tube 24 to deliver the thrombolytic drug through the outer tube 24. In this way, there is no need to set up a drug delivery pipeline separately, which reduces the complexity of the structure. It should be noted that during the advancement of the delivery component, the thrombus removal stent 1 is stored inside the outer tube 24 to avoid affecting the advancement. In addition, the thrombus removal stent 1 is released after the thrombolytic pretreatment. In this way, the end 21 can be blocked at one end of the outer tube 24 and tightly matched with the outer tube 24, so that a sealed space is formed at one end of the outer tube 24 adjacent to the spray hole 241. When injecting thrombolytic drugs, they can be sprayed out at the spray hole 241 to avoid leakage of thrombolytic drugs at the end of the outer tube 24, so as to improve the accuracy of thrombolysis. After reaching the position of the thrombus 200, the middle tube 23 and the inner tube 22 can be pushed to release the thrombus removal stent 1, so as to facilitate the mechanical thrombus removal operation. Optionally, a first developing device 26 and a second developing device 27 can be respectively provided at both ends of the thrombus removal stent 1 to facilitate observation of the position of the thrombus removal stent 1. Optionally, the material of the developing device is a platinum-iridium alloy.

[0051] Exemplarily, one end of the thrombus removal stent 1 is connected to one end of the inner tube 22 adjacent to the end 21, and the other end is connected to the intermediate tube 23, so that the inner tube 22 can move axially relative to the intermediate tube 23, thereby adjusting the axial length of the thrombus removal stent 1 to facilitate subsequent thrombus removal operations. Optionally, the thrombus removal stent 1 is composed of a mesh structure, which is woven from nickel-titanium wires in a mesh tube shape and molded, and the connection of the nickel-titanium wires is smoothly transitioned. Optionally, the thrombus removal stent 1 can be recovered as a whole into the suction catheter 25 after the thrombus 200 is removed to complete the removal of the thrombus 200.

[0052] Understandably, traditional single thrombus treatment methods, whether thrombolysis or mechanical thrombectomy, cannot effectively treat thrombus problems. Clinically, there is an urgent need for a thrombus treatment device that can not only improve the effect of catheter thrombolysis, but also completely remove thrombi and prevent thrombus escape.

[0053] According to the thrombus removal device 100 of the embodiment of the present invention, the inner tube 22, the middle tube 23 and the outer tube 24, which are movably sleeved in sequence, are partially passed through the thrombus 200 through the end 21, so that the spraying hole 241 on the outer tube 24 corresponds to the thrombus 200. In this way, the thrombus 200 is pre-treated by injecting thrombolytic drugs into the outer tube 24, and part of the thrombus 200 is dissolved. At the same time, the middle tube 23 and the inner tube 22 inside the outer tube 24 are movable. After the outer tube 24 passes through the thrombus 200 and injects thrombolytic drugs to pre-treat the thrombus 200, the middle tube 23 and the inner tube 22 extend, thereby driving the thrombus removal stent 1 to be exposed outside the outer tube 24, and moving the outer tube 24 toward the tube mouth of the suction catheter 25, so that the thrombus removal stent 1 drives the thrombus 200 to the suction catheter 25 for suction, thereby removing the thrombus 200. By combining thrombolysis and mechanical thrombus removal, the thrombus removal effect and efficiency are improved. It is understandable that before the thrombus removal stent 1 is released, thrombolytic drugs can be injected to pre-treat the thrombus 200, which can not only significantly reduce the dosage and time of thrombolytic drugs, thereby reducing serious complications such as thrombolytic bleeding, but also achieve a minimally invasive effect. At the same time, after the advance thrombolytic treatment, the thrombus 200 will be partially softened or ruptured, which improves the efficiency of subsequent cutting and pulling of the thrombus 200, and can reduce the residual thrombus 200.

[0054] Please refer to Figure 3 and Figure 4 According to one embodiment of the present invention, a receiving section 242 is provided at one end of the outer tube 24 adjacent to the terminal 21, and the thrombus removal bracket 1 can be received in the receiving section 242. The outer tube 24 is also provided with a spraying section 243, which is disposed adjacent to the receiving section 242. The spraying section 243 is located at one end of the receiving section 242 away from the terminal 21, and the spraying hole 241 is disposed in the spraying section 243.

[0055] In this embodiment, the length of the storage section 242 is adapted to the length of the thrombus removal bracket 1, so as to facilitate the storage of the thrombus removal bracket 1. That is, the storage section 242 and the medicine spraying section 243 are sequentially provided in the direction away from the end of the outer tube 24 from the end head 21, and the medicine spraying hole 241 is provided in the medicine spraying section 243. In this way, when the thrombus removal bracket 1 is stored in the storage section 242, the thrombus removal bracket 1 will not block the medicine spraying hole 241, and the thrombus removal bracket 1 will not hinder the thrombolytic drug from being sprayed from the medicine spraying hole 241, so that the thrombolytic drug can be smoothly sprayed from the medicine spraying hole 241, thereby improving the thrombolytic efficiency. It can be understood that in order to prevent the medicine spraying hole 241 from being blocked by the thrombus removal bracket 1 corresponding to the thrombus removal bracket 1, the thrombus removal bracket 1 is stored in the storage section 242, and the medicine spraying hole 241 is provided in the medicine spraying section 243, so as to separate the two. In addition, even if the thrombus removal stent 1 does not block the drug spraying hole 241, the arrangement of the thrombus removal stent 1 corresponding to the drug spraying hole 241 is likely to affect the efficiency of the thrombolytic drug spraying from the drug spraying hole 241. Exemplarily, after the receiving section 242 passes through the thrombus 200, the drug spraying section 243 is located at the thrombus 200, so that the drug is sprayed for thrombolysis, and then the receiving section 242 releases the thrombus removal stent 1 to block the fragments of the thrombus 200, so as to prevent it from escaping to the distal end of the branch vessel and causing secondary blockage, thereby improving the thrombus removal effect.

[0056] According to one embodiment of the present invention, the number of the medicine spraying holes 241 is multiple, and the multiple medicine spraying holes 241 are evenly distributed along the circumference of the medicine spraying section 243. It can be understood that the multiple medicine spraying holes 241 can be spread all over the medicine spraying section 243, and the multiple medicine spraying holes 241 are evenly distributed along the circumference of the medicine spraying section 243, so that the thrombolytic drug can be evenly sprayed along the circumference of the medicine spraying section 243 to improve the thrombolytic efficiency. Optionally, the length of the medicine spraying section 243 is set to 40-60 mm.

[0057] like Figure 5 As shown, according to one embodiment of the present invention, the thrombus removal bracket 1 includes a main body 10, a first net dish 11, a first net bag 12 and a second net bag 13, the main body 10 is sleeved on the inner tube 22 and the middle tube 23, one end of the main body 10 is connected to the end 21, and the other end is connected to an end of the middle tube 23 adjacent to the end 21; the first net dish 11 is arranged at one end of the main body 10 adjacent to the end 21; the first net bag 12 is arranged on the main body 10, and is located on the side of the first net dish 11 facing away from the end 21; the second net bag 13 is arranged on the main body 10, and is located on the side of the first net bag 12 facing away from the end 21; wherein, the diameter of the first net dish 11 is greater than the diameters of the first net bag 12 and the second net bag 13.

[0058] In this embodiment, the first net plate 11, the first net bag 12 and the second net bag 13 are sequentially arranged at intervals on the body 10. After the thrombus 200 is subjected to thrombolysis, the thrombus removal stent 1 is recovered, and the thrombus 200 is cut and partially intercepted by the first net bag 12 and the second net bag 13. Then, the first net plate 11 intercepts the broken thrombus 200, so as to remove the thrombus 200. Of course, multiple net plates or multiple net bags can also be provided to improve the cutting effect of the thrombus 200 and the interception effect of the broken thrombus 200. Among them, the diameter of the net plate is larger than the diameter of the net bag, so that the net plate can better intercept the thrombus 200. Optionally, the mesh disk and the mesh bag are both woven from silk materials, and the weaving density of the mesh disk is greater than that of the mesh bag. In addition, the wire diameter of the mesh disk can be set smaller than that of the mesh bag. In this way, the mesh of the mesh disk is tight, and its supporting force with the inner wall of the blood vessel is small, so that it can fit closely to the blood vessel without damaging the inner wall of the blood vessel; while the mesh of the mesh bag is sparse, and its supporting force is large, so that large blood clots can be effectively cut 200.

[0059] In this embodiment, the whole mesh structure of the thrombus removal stent 1 can be made of nickel-titanium shape memory alloy wire, which is a self-expanding metal stent. That is, when the thrombus removal stent 1 is released outside the outer tube 24, the first mesh plate 11, the first mesh bag 12 and the second mesh bag 13 automatically expand and open to form a disc-shaped structure, so as to achieve the effect of intercepting the thrombus 200. Figure 6 As shown, it can be understood that the diameter of the first net plate 11 is set to be larger than the diameter of the first net bag 12 and the second net bag 13. When the thrombus removal stent 1 is released, the first net plate 11 contacts the blood vessel wall, so that the first net plate 11 can intercept the thrombus 200 and prevent the thrombus 200 from escaping. At the same time, the first net bag 12 and the second net bag 13 have smaller diameters and are used to cut the thrombus 200. Due to their smaller diameters, they will not contact the blood vessel wall after release, avoiding damage to the blood vessel wall. Please refer to Figure 6 and Figure 7It can be understood that the first net plate 11, the first net bag 12 and the second net bag 13 are all woven from nickel-titanium wires. Optionally, the weaving density of the first net plate 11 is set to be greater than the weaving density of the first net bag 12 and the second net bag 13. In this way, the contact area between the first net plate 11 and the thrombus 200 is larger, so as to improve its ability to block and break the thrombus 200; while the weaving density of the first net bag 12 and the second net bag 13 is smaller, the contact area between the first net plate 11 and the thrombus 200 is smaller, and the cutting force on the thrombus 200 is greater, so as to improve its ability to cut the thrombus 200. Optionally, the wire diameter of the first net plate 11 is set to be smaller than the wire diameter of the first net bag 12 and the second net bag 13. The mesh of the first net plate 11 is tight, and its supporting force with the inner wall of the blood vessel is small, so as to fit the blood vessel closely without damaging the inner wall of the blood vessel; while the mesh of the first net bag 12 and the second net bag 13 is sparse, and the supporting force is greater, so as to effectively cut large thrombi 200. It should be noted that the first net bag 12 and the second net bag 13 effectively break up the thrombus 200 , and perform distal blocking through the first net plate 11 , and finally the thrombus 200 is sucked out through the suction catheter 25 , thereby completing the removal of the thrombus 200 .

[0060] like Fig. 9 As shown, according to one embodiment of the present invention, the first mesh plate 11 is curved in an arc shape in the direction away from the end head 21. That is, the first mesh plate 11 can be in a wing shape, an umbrella shape, or a cone shape, so as to increase the fit between the first mesh plate 11 and the blood vessel wall and enhance the blocking ability of breaking the thrombus 200.

[0061] like Figure 8 As shown, according to one embodiment of the present invention, the first mesh plate 11 is provided with a coating 111. It is understandable that the coating 111 can be provided on one side of the first mesh plate 11 close to the end 21, and the coating 111 covers the mesh holes to further collect and block the escaping broken thrombus 200, thereby improving the thrombus removal effect.

[0062] Please refer to Fig.10 and Fig.11According to one embodiment of the present invention, the first net bag 12 includes a first section 121 and a second section 122 connected in a direction away from the end 21, and the taper of the first section 121 is the same as the taper of the second section 122, that is, the projection areas of the first section 121 and the second section 122 on the body 10 are the same, that is, the first section 121 and the second section 122 are combined to form a flying saucer shape, that is, the first section 121 and the second section 122 are symmetrically arranged. Alternatively, the taper of the first section 121 is greater than the taper of the second section 122, that is, the projection area of ​​the first section 121 on the body 10 is smaller than the projection area of ​​the second section 122 on the body 10, that is, the first section 121 and the second section 122 are combined to form a bud shape, the first section 121 is close to the end 21, and the second section 122 is far away from the end 21, and the thrombus 200 is mainly cut by the second section 122. Thus, the surface area of ​​the second section 122 is greater than that of the first section 121 , the braided wires at the second section 122 are more sparse, and the second section 122 cuts the thrombus 200 to improve the cutting ability of cutting large thrombus 200 .

[0063] Optionally, the second net bag 13 includes a third section 131 and a fourth section 132 connected in a direction away from the end 21, and the taper of the third section 131 is the same as the taper of the fourth section 132, or the taper of the third section 131 is greater than the taper of the fourth section 132. It can be understood that the third section 131 has the same structure and function as the first section 121, and the fourth section 132 has the same structure and function as the second section 122, which will not be repeated here.

[0064] like Fig.12 and Fig.14 As shown, according to one embodiment of the present invention, the thrombus removal bracket 1 further includes a second mesh plate 14, which is disposed between the first mesh plate 11 and the first net bag 12, and the diameter of the second mesh plate 14 is smaller than the diameter of the first mesh plate 11. It can be understood that the first mesh plate 11 has a smaller metal wire diameter and a smaller supporting force, and the force of pulling the thrombus 200 as a whole is limited for old mural thrombi 200. In order to increase the ability to intercept and pull the thrombi 200, a second mesh plate 14 can be added to the side of the first mesh plate 11 facing away from the end 21. Optionally, the diameter of the second mesh plate 14 is smaller than that of the first mesh plate 11, the braided wires are closely arranged, and the wire diameter is consistent with that of the first mesh plate 11.

[0065] like Fig.13 and Fig.14As shown, according to one embodiment of the present invention, the thrombus removal stent 1 further includes a third net bag 15, which is disposed between the first net bag 12 and the second net bag 13, and the diameter of the third net bag 15 is smaller than the diameters of the first net bag 12 and the second net bag 13. In this embodiment, in order to increase the ability of the thrombus removal stent 1 to pull out the thrombus 200, a third net bag 15 can be added between the first net bag 12 and the second net bag 13, the overall structure of the third net bag 15 is the same as the second net bag 13, and the diameter of the third net bag 15 is slightly smaller. When removing the thrombus, the third net bag 15 can cooperate with the first net bag 12 and the second net bag 13 to cut the large thrombus 200 to different degrees, thereby increasing the ability to remove the thrombus.

[0066] Please refer to Figures 15 to 17 In one embodiment, the thrombus removal process is as follows: first, the assembled thrombus removal stent 1 is delivered to the site of the thrombus 200 through the conveying assembly, the position is determined by the developing device of the thrombus removal stent 1, and the outer tube 24 with the spray hole 241 is placed inside the thrombus 200, and thrombolytic treatment is performed by injecting thrombolytic drugs; then the thrombus removal stent 1 is released, and according to the developing device, the first net plate 11 of the thrombus removal stent 1 is released at the distal end of the thrombus 200, the first net bag 12 and the second net bag 13 are released in the thrombus 200, the release position is adjusted by pushing the inner tube 22, and the middle tube 23 is pulled to achieve the cutting of the thrombus 200, which can be repeated. The outer tube 24 is pulled to pull the entire thrombus removal stent 1 and the thrombus 200 to the mouth of the suction catheter 25 for suction, so as to achieve the complete removal of the thrombus 200.

[0067] Finally, it should be noted that the above embodiments are only used to illustrate the present invention, rather than to limit the present invention. Although the present invention is described in detail with reference to the embodiments, it should be understood by those skilled in the art that various combinations, modifications or equivalent substitutions of the technical solutions of the present invention do not depart from the spirit and scope of the technical solutions of the present invention, and should be included in the scope of the claims of the present invention.

Claims

1. A thrombus removal device, characterized in that: include: A delivery assembly, the delivery assembly comprises an end cap, an inner tube, an intermediate tube, an outer tube and a suction catheter, the end cap is connected to one end of the inner tube, the intermediate tube is movably sleeved on the inner tube, the outer tube is movably sleeved on the intermediate tube, a spray hole is provided on the tube wall of the outer tube, the outer tube is suitable for delivering thrombolytic drugs to be sprayed from the spray hole, the suction catheter is movably sleeved on the outer tube, and the suction catheter is suitable for suctioning thrombus; a thrombus removal bracket, one end of which is connected to the end head, and the other end of which is connected to an end of the intermediate tube adjacent to the end head, the thrombus removal bracket being sleeved on the outside of the inner tube and the intermediate tube, and the thrombus removal bracket moving with the inner tube and the intermediate tube to be exposed outside the outer tube or received inside the outer tube; The outer tube has a storage section at one end adjacent to the end head, and the thrombus removal bracket can be stored in the storage section. The outer tube is also provided with a spraying section, which is arranged adjacent to the storage section. The spraying section is located at one end of the storage section away from the end head, and the spraying hole is arranged in the spraying section.

2. The thrombus removal device according to claim 1, characterized in that: There are multiple spray holes, and the multiple spray holes are evenly distributed along the circumference of the spray section.

3. The thrombus removal device according to claim 1, characterized in that: The thrombus removal stent comprises: A body, wherein the body is sleeved on the inner tube and the middle tube, one end of the body is connected to the end head, and the other end of the body is connected to an end of the middle tube adjacent to the end head; A net disk, the net disk being arranged at one end of the body adjacent to the end head; At least two net bags, which are arranged on the body and located on the side of the net plate facing away from the end head, with a predetermined distance between adjacent net bags, and at least two net bags having the same or different diameters; Wherein, the diameter of the net disk is greater than the diameter of the net bag.

4. The thrombus removal device according to claim 3, characterized in that: The mesh plate is curved in an arc shape in a direction away from the end head.

5. The thrombus removal device according to claim 3, characterized in that: The mesh disk is provided with a covering film.

6. The thrombus removal device according to claim 3, characterized in that: The net bag comprises a first section and a second section connected in a direction away from the end head, and the taper of the first section of part or all of the net bag is the same as or different from the taper of the second section.

7. The thrombus removal device according to claim 3, characterized in that: The thrombus removal bracket also includes a plurality of mesh disks, all of which are located on the side of the net bag facing the end head, with a spacing between adjacent mesh disks, and a diameter of the mesh disk adjacent to the end head being larger than a diameter of the other mesh disks.

8. The thrombus removal device according to any one of claims 3 to 7, characterized in that: The net disk and the net bag are both formed by weaving silk materials, and the weaving density of the net disk is greater than that of the net bag.

9. The thrombus removal device according to claim 8, characterized in that: The wire diameter of the net disk is smaller than the wire diameter of the net bag.

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