Mass spectrometer air curtain baffle automatic cleaning device and method

Abstract

The present invention discloses an automatic cleaning device and method for a mass spectrometer air curtain baffle, comprising: an ion source body, which is hollow inside to form a accommodating chamber, wherein an air curtain baffle is arranged in the accommodating chamber; a cleaning component, which is provided with no less than two groups, and the two cleaning components are symmetrically arranged, and the cleaning component is connected to the accommodating chamber; and a controller, which is electrically or wirelessly connected to the cleaning component. According to the present invention, the cleaning solvent in the first material storage part and the second material storage part is successively transported by a cleaning driver to automatically clean the air curtain baffle through a cleaning head, without the need for tedious manual disassembly of the ion source for cleaning, the cleaning is fast, the cleaning effect is good, the cleaning time is greatly shortened, the cleaning efficiency of the ion source is improved, the operation of the staff is convenient, and the service life of the equipment is improved, so that the detection sensitivity of the equipment after cleaning is enhanced, the detection accuracy of the equipment is high, and the detection efficiency of the equipment is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of mass spectrometry analysis, and more specifically, to an automatic cleaning device for a mass spectrometer air curtain baffle, and also to a cleaning method for a mass spectrometer air curtain baffle. Background Art

[0002] Mass spectrometry is an analytical method for measuring the charge-mass ratio of ions. It can be used to analyze isotopic composition, organic structure and elemental composition. Its basic principle is to ionize the components in the sample in the ion source to generate positively charged ions with different charge-mass ratios. After the acceleration electric field, an ion beam is formed and enters the mass analyzer. In the mass analyzer, the electric field and magnetic field are used to cause opposite velocity dispersion, and they are focused separately to obtain a mass spectrum to determine their mass. Mass spectrometers are generally composed of sample introduction system, ion source, mass analyzer, detector, data processing system and other parts. The ion source is a device that ionizes neutral atoms or molecules and extracts ion beams from them. It is an indispensable component of various types of mass spectrometers. The performance of the ion source determines the ionization efficiency and, to a large extent, the sensitivity of the mass spectrometer. There are two common ionization methods: one is that the sample is ionized in the form of gas in the ion source, and the other is that charged ions are sputtered from the solid surface or solution. In many cases, sampling and ionization are carried out simultaneously.

[0003] The air curtain baffle (Cutain Plate) is a partial structure for ion transmission. On the one hand, it can block impurity ions, and on the other hand, it can avoid ion clustering as much as possible. Since the equipment detects a large number of samples every day, it is easy for the air curtain baffle to accumulate various salts, strong acid reagents, strong base reagents, non-volatile ion pair reagents, etc., which in turn causes signal suppression and contaminates the ion source. Therefore, during the detection process, the ion source needs to be frequently disassembled and the air curtain baffle cleaned. The current equipment does not have an automatic cleaning function, and the experimenter needs to judge whether it should be cleaned based on the detection situation and visual observation. In addition, during the cleaning process, the equipment needs to be put in standby mode first, the ion source needs to be disassembled, and then cleaned and dried with dust-free paper, and finally the ion source needs to be reinstalled, which undoubtedly greatly increases the workload of the experimenter.

[0004] In view of this, it is necessary to develop an automatic cleaning device and method for the air curtain baffle of a mass spectrometer to solve the above problems. Summary of the invention

[0005] In view of the shortcomings of the prior art, the main purpose of the present invention is to provide an automatic cleaning device for the air curtain baffle of a mass spectrometer, which uses a cleaning driver to successively transport the cleaning solvent in the first material storage part and the second material storage part through the cleaning head to automatically clean the air curtain baffle, without the need for cumbersome manual disassembly of the ion source for cleaning, with fast cleaning and good cleaning effect, greatly shortening the cleaning time, improving the cleaning efficiency of the ion source, facilitating the operation of the staff, and at the same time prolonging the service life of the equipment, thereby enhancing the detection sensitivity of the equipment after cleaning, and the detection accuracy of the equipment is high, and the detection efficiency of the equipment is improved. .

[0006] In order to achieve these purposes and other advantages according to the present invention, there is provided an automatic cleaning device for a mass spectrometer air curtain baffle, comprising: an ion source body, the interior of which is hollow to form an accommodating cavity, wherein the air curtain baffle is arranged in the accommodating cavity;

[0007] A cleaning assembly, which is provided in at least two groups, and the two cleaning assemblies are arranged symmetrically, and the cleaning assembly is connected to the accommodating chamber; and

[0008] A controller, which is electrically or wirelessly connected to the cleaning component;

[0009] Wherein, the cleaning assembly comprises: a cleaning head, which is fixedly mounted on the ion source body, and the output port of the cleaning head is connected to the accommodating cavity;

[0010] A cleaning driver, whose output end is connected to the cleaning head and the cleaning head, and the cleaning driver is electrically or wirelessly connected to the controller;

[0011] A first material storage member connected to an input end of the cleaning drive; and

[0012] A second material storage member, which is connected to the input end of the cleaning drive;

[0013] The first material storage member and the second material storage member both store cleaning solvents. Under the control of the controller, the cleaning driver respectively transports the cleaning solvents in the first material storage member and the second material storage member to clean the air curtain baffle through the cleaning head.

[0014] Preferably, the cleaning component also includes: a three-way valve, which is electrically or wirelessly connected to the controller, and the output end of the three-way valve is connected to the input end of the cleaning driver, the first input end of the three-way valve is connected to the controller, and the second input end of the three-way valve is connected to the controller.

[0015] Preferably, the cleaning solvents stored in the first material storage member and the second material storage member are different.

[0016] Preferably, it further comprises: a sprayer fixedly installed in the accommodating cavity;

[0017] No less than two auxiliary heaters are arranged, and the auxiliary heaters are fixedly installed in the accommodating cavity; and

[0018] A baffle, which is movably arranged in the accommodating cavity;

[0019] The sprayer and the auxiliary heater are both electrically or wirelessly connected to the controller.

[0020] Preferably, a temperature sensor and a temperature alarm are arranged in the accommodating chamber, and the temperature sensor and the temperature alarm are both electrically or wirelessly connected to the controller. The temperature sensor is used to sense the temperature of the accommodating chamber.

[0021] When the temperature sensor senses that the temperature in the accommodation chamber is abnormal, the temperature alarm issues an abnormal alarm.

[0022] On the other hand, the present invention further provides a method for cleaning a mass spectrometer air curtain baffle, the method being applied to the automatic cleaning device for the mass spectrometer air curtain baffle as described in any one of the above items, the method comprising the following steps:

[0023] The control baffle blocks the tapered hole of the air curtain baffle;

[0024] Control reagent A to automatically flush the air curtain baffle at a certain rate for a certain period of time;

[0025] Control reagent B to automatically flush the air curtain baffle at a certain rate for a certain period of time;

[0026] Heat and dry the air curtain baffle for a certain period of time;

[0027] The control baffle returns to its original position automatically.

[0028] Preferably, the reagent A is methanol water, and the reagent B is methanol.

[0029] Preferably, the controlling reagent A to automatically flush the air curtain baffle at a certain rate for a certain period of time comprises:

[0030] The cleaning drive delivers reagent A at a rate of 10 μL / min-30 μL / min through the cleaning head to automatically flush the air curtain baffle for 2 minutes.

[0031] Preferably, the controlling reagent B to automatically flush the air curtain baffle at a certain rate for a certain period of time comprises:

[0032] The cleaning drive delivers reagent B at a rate of 10 μL / min-30 μL / min through the cleaning head to automatically flush the air curtain baffle for 2 minutes.

[0033] Preferably, the step of heating and drying the air curtain baffle for a certain period of time comprises:

[0034] Control the nebulizer to start and provide atomizing gas at a flow rate of 30 to 70 psi;

[0035] Control the auxiliary heater to start, heat the temperature to 100-200°C, and heat and dry the air curtain baffle for 1 minute.

[0036] One of the above technical solutions has the following advantages or beneficial effects: the present invention uses a cleaning driver to successively transport the cleaning solvent in the first material storage part and the second material storage part through the cleaning head to automatically clean the air curtain baffle, without the need for tedious manual disassembly of the ion source for cleaning. The cleaning is fast and the cleaning effect is good, which greatly shortens the cleaning time, improves the cleaning efficiency of the ion source, facilitates the operation of the staff, and at the same time increases the service life of the equipment, thereby enhancing the detection sensitivity of the equipment after cleaning, and the equipment detection accuracy is high, thereby improving the detection efficiency of the equipment.

[0037] Other advantages, objectives and features of the present invention will be embodied in part through the following description, and in part will be understood by those skilled in the art through study and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings of the embodiments are briefly introduced below. Obviously, the drawings in the following description only relate to some embodiments of the present invention, but are not intended to limit the present invention.

[0039] Figure 1 A three-dimensional structural view of an automatic cleaning device for an air curtain baffle of a mass spectrometer according to an embodiment of the present invention;

[0040] Figure 2 A rear view of an automatic cleaning device for an air curtain baffle of a mass spectrometer according to one embodiment of the present invention;

[0041] Figure 3 The figure is a flow chart of a method for cleaning a gas curtain baffle of a mass spectrometer according to one embodiment of the present invention. DETAILED DESCRIPTION

[0042] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0043] In the drawings, the shapes and dimensions may be exaggerated for clarity, and the same reference numerals will be used throughout to designate the same or like components.

[0044] Unless otherwise defined, the technical or scientific terms used herein shall have the usual meanings understood by persons of ordinary skill in the field to which the invention belongs. The words "first", "second" and similar words used in the patent application specification and claims of the present invention do not indicate any order, quantity or importance, but are only used to distinguish different components. Similarly, words such as "one", "one" or "the" do not indicate a quantity limitation, but indicate the existence of at least one. Words such as "include" or "comprise" and similar words mean that the elements or objects appearing before "include" or "comprise" include the elements or objects listed after "include" or "comprise" and their equivalents, and do not exclude other elements or objects. "Up", "down", "left", "right" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0045] In the following description, words such as center, thickness, height, length, front, back, rear, left, right, top, bottom, upper, lower, etc. are defined relative to the structure shown in the drawings. In particular, "height" is equivalent to the dimension from top to bottom, "width" is equivalent to the dimension from left to right, and "depth" is equivalent to the dimension from front to back. They are relative concepts and may change accordingly according to their different positions and different usage states. Therefore, these or other directions should not be interpreted as restrictive terms.

[0046] Terms related to attachment, coupling and the like (eg, "connected" and "attached") refer to a relationship in which structures are directly or indirectly fixed or attached to each other through intermediate structures, as well as a relationship in which they are movable or rigidly attached, unless expressly stated otherwise.

[0047] According to one embodiment of the present invention, Figures 1-2 As shown in the figure, it can be seen that the mass spectrometer air curtain baffle automatic cleaning device 100 includes: an ion source body 110, the interior of which is hollow to form a receiving chamber 111, and an air curtain baffle 112 is arranged in the receiving chamber 111;

[0048] No less than two cleaning assemblies 120 are provided, and the two cleaning assemblies 120 are arranged symmetrically, and the cleaning assemblies 120 are connected to the accommodating chamber 111; and

[0049] A controller, which is electrically or wirelessly connected to the cleaning component 120;

[0050] The cleaning assembly 120 includes: a cleaning head 121, which is fixedly mounted on the ion source body 110, and the output port of the cleaning head 121 is connected to the accommodating chamber 111;

[0051] A cleaning driver 122, whose output end is connected to the cleaning head 121 and the cleaning head 121, and the cleaning driver 122 is electrically or wirelessly connected to the controller;

[0052] A first material storage member 123, which is connected to the input end of the cleaning driver 122; and

[0053] A second material storage member 124, which is connected to the input end of the cleaning driver 122;

[0054] The first material storage member 123 and the second material storage member 124 both store cleaning solvents. Under the control of the controller, the cleaning driver 122 respectively transports the cleaning solvents in the first material storage member 123 and the second material storage member 124 to clean the air curtain baffle 112 through the cleaning head 121 .

[0055] It is understandable that during the experiment of the mass spectrometer, salt, organic solvent and sample impurities will be generated on the air curtain baffle 112 on the ion source body 110, which needs to be cleaned in time. After each normal detection work of the equipment is completed, the present invention uses the cleaning driver 122 to successively transport the cleaning solvent in the first storage part 123 and the second storage part 124 through the cleaning head 121 to automatically clean the air curtain baffle 112. There is no need for tedious manual disassembly of the ion source for cleaning. The cleaning is fast and the cleaning effect is good, which greatly shortens the cleaning time, improves the cleaning efficiency of the ion source, facilitates the operation of the staff, and at the same time increases the service life of the equipment, thereby enhancing the detection sensitivity of the equipment after cleaning, and the detection accuracy of the equipment is high, thereby improving the detection efficiency of the equipment.

[0056] In a preferred embodiment of the present invention, the controller may be a conventional product or a conventional control chip or other conventional products that can realize the control function of the present invention. The present invention does not make specific restrictions. The control chip is installed on the ion source body 110 .

[0057] The cleaning head 121 and the air curtain baffle 112 are arranged at a certain angle. The angle between the axial direction of the cleaning head 121 and the air curtain baffle 112 is defined as α, and the angle α is 50° to 70°.

[0058] In one embodiment of the present invention, the angle α is 50°, in another embodiment of the present invention, the angle α is 70°, and in yet another embodiment of the present invention, the angle α is 60°.

[0059] The staff can make a specific selection of the angle between the axial direction of the cleaning head 121 and the air curtain baffle 112 according to the actual situation.

[0060] In the present invention, the angle between the cleaning head 121 and the air curtain baffle 112 is limited to improve the cleaning efficiency, so that the cleaning component has a better cleaning effect.

[0061] Furthermore, the cleaning component 120 also includes: a three-way valve 125, which is electrically or wirelessly connected to the controller, and the output end of the three-way valve 125 is connected to the input end of the cleaning driver 122, the first input end of the three-way valve 125 is connected to the first material storage part 123, and the second input end of the three-way valve 125 is connected to the second material storage part 124.

[0062] Specifically, when the cleaning driver 122 delivers the cleaning solvent in the first material storage member 123 to clean the air curtain baffle 112 through the cleaning head 121, the controller sends a control instruction to the three-way valve 125 to control the three-way valve 125 to connect the cleaning driver 122 with the first material storage member 123;

[0063] When the cleaning driver 122 delivers the cleaning solvent in the second material storage member 124 to clean the air curtain baffle 112 through the cleaning head 121 , the controller sends a control instruction to the three-way valve 125 to control the three-way valve 125 to connect the cleaning driver 122 with the second material storage member 124 .

[0064] In the present invention, a three-way valve 125 is provided to enable a single cleaning driver 122 to separately deliver cleaning solvents to a plurality of material storage members, without the need to provide a plurality of cleaning drivers, thereby simplifying the structure and reducing the cost.

[0065] Furthermore, the cleaning solvents stored in the first material storage member 123 and the second material storage member 124 are different.

[0066] In a preferred embodiment of the present invention, the cleaning solvent stored in the first storage member 123 is methanol water, and the cleaning solvent stored in the second storage member 124 is methanol.

[0067] The first material storage part 123 and the second material storage part 124 are both provided with material presence sensors and empty alarms, and the material presence sensors and the empty alarms are both electrically or wirelessly connected to the controller. The material presence sensors are used to sense whether there is cleaning solvent in the first material storage part 123 and the second material storage part 124.

[0068] When the material presence sensor senses that there is no cleaning solvent in the first material storage part 123 or the second material storage part 124, the material presence sensor sends a feedback signal to the controller. After receiving the feedback signal, the controller sends a control instruction to the vacancy alarm according to the feedback result to control the vacancy alarm to issue an vacancy alarm, so as to remind the staff to replenish the cleaning solvent to the first material storage part 123 or the second material storage part 124 in time.

[0069] In one embodiment of the present invention, the vacancy alarm can be light, sound, image, text, etc. In a preferred embodiment of the present invention, the vacancy alarm is sound, and the vacancy alarm sounds emitted by the corresponding alarms on the first storage component 123 and the second storage component 124 are different, so that the staff can distinguish which storage component is empty and perform corresponding operations.

[0070] Furthermore, the mass spectrometer air curtain baffle automatic cleaning device 100 further includes: a sprayer 130, which is fixedly installed in the accommodating chamber 111;

[0071] No less than two auxiliary heaters 140 are arranged, and the auxiliary heaters 140 are fixedly installed in the accommodating cavity 111; and

[0072] A baffle (not shown), which is movably arranged in the accommodating cavity 111;

[0073] The sprayer 130 and the auxiliary heater 140 are both electrically or wirelessly connected to the controller.

[0074] It is understandable that a sampling cone hole is provided in the central area of ​​the air curtain baffle 112. When the air curtain baffle 112 is cleaned, the sampling cone hole needs to be blocked. In the present invention, a baffle is provided. When the air curtain baffle 112 is automatically cleaned, the baffle blocks the sampling cone hole under the action of a driving force, thereby preventing the automatic cleaning device from contaminating other components when performing an automatic cleaning operation on the air curtain baffle, thereby affecting the detection efficiency of the overall equipment.

[0075] In a specific embodiment of the present invention, the driving force may be provided by a worker, or the driving force may be provided by a driving device such as a motor.

[0076] When the cleaning driver 122 respectively transports the cleaning solvents in the first material storage member 123 and the second material storage member 124 through the cleaning head 121 to clean the air curtain baffle 112, the controller sends control instructions to the sprayer 130 and the auxiliary heater 140 respectively to control the start-up of the sprayer 130, the sprayer 130 provides atomizing gas, and synchronously controls the start-up of the auxiliary heater 140 to form a heating environment in the accommodating cavity 111, so as to heat and dry the air curtain baffle 112.

[0077] In a preferred embodiment of the present invention, the mass spectrometer air curtain baffle automatic cleaning device 100 also includes: a waste liquid discharge port 150, wherein the waste liquid discharge port 150 is located in the bottom area of ​​the ion source body 110, and one end of the waste liquid discharge port 150 is connected to the accommodating cavity 111, and the other end of the waste liquid discharge port 150 is connected to an external waste liquid recovery device.

[0078] Specifically, the cleaning driver 122 transports the cleaning solvent in the first material storage part 123 and the second material storage part 124 to clean the air curtain baffle 112, and discharges the waste liquid generated through the waste liquid discharge port 150 to an external waste liquid recovery device for recovery to prevent secondary pollution.

[0079] Furthermore, a temperature sensor and a temperature alarm are arranged in the accommodating chamber 111. The temperature sensor and the temperature alarm are both electrically or wirelessly connected to the controller. The temperature sensor is used to sense the temperature of the accommodating chamber 111.

[0080] When the temperature sensor senses that the temperature in the accommodation chamber 111 is abnormal, the temperature alarm issues an abnormal alarm.

[0081] When the auxiliary heater 140 heats and dries the air curtain single plate 112, the temperature sensor senses the temperature of the accommodating cavity 111. When the temperature sensor senses that the temperature in the accommodating cavity 111 is abnormal, the temperature sensor sends a feedback signal to the controller. The controller receives the feedback signal and sends control instructions to the temperature alarm and the auxiliary heater 140 respectively according to the feedback result, so as to control the temperature alarm to issue an abnormal alarm and control the auxiliary heater 140 to adjust the temperature.

[0082] Specifically, when the temperature sensor senses that the temperature in the accommodating chamber 111 is lower than a predetermined temperature, the temperature sensor sends a feedback signal to the controller, and the controller receives the feedback signal and sends a control instruction to the auxiliary heater 140 according to the feedback result, so as to control the auxiliary heater 140 to increase the temperature in the accommodating chamber 111;

[0083] When the temperature sensor senses that the temperature in the accommodating cavity 111 is higher than a predetermined temperature, the temperature sensor sends a feedback signal to the controller. The controller receives the feedback signal and sends a control instruction to the auxiliary heater 140 based on the feedback result to control the auxiliary heater 140 to lower the temperature in the accommodating cavity 111.

[0084] The present invention monitors the temperature in the accommodating cavity 111 by arranging a temperature sensor and a temperature alarm to prevent the auxiliary heater 140 from heating and drying the air curtain single plate 112 at a temperature that is too low, resulting in low heating and drying efficiency and affecting the heating and drying effect. At the same time, the auxiliary heater 140 is prevented from heating and drying the air curtain single plate 112 at a temperature that is too high, causing damage to components.

[0085] On the other hand, combined Figure 3 The present invention also provides a method for cleaning a mass spectrometer air curtain baffle, the method being applied to the mass spectrometer air curtain baffle automatic cleaning device as described in any one of the above items, the method comprising the following steps:

[0086] Step S1, controlling the blocking piece to block the tapered hole of the air curtain baffle;

[0087] Step S2, controlling reagent A to automatically flush the air curtain baffle at a certain rate for a certain period of time;

[0088] Step S3, controlling reagent B to automatically flush the air curtain baffle at a certain rate for a certain period of time;

[0089] Step S4, heating and drying the air curtain baffle for a certain period of time;

[0090] Step S5, controlling the baffle to automatically return to its original position.

[0091] Furthermore, the reagent A is methanol water, and the reagent B is methanol.

[0092] Further, in step S2, the controlling reagent A to automatically flush the air curtain baffle at a certain rate for a certain period of time includes:

[0093] The cleaning drive delivers reagent A at a rate of 10 μL / min-30 μL / min through the cleaning head to automatically flush the air curtain baffle for 2 minutes.

[0094] Specifically, in one embodiment of the present invention, the cleaning driver transports reagent A through the cleaning head to automatically flush the air curtain baffle at a rate of 10 μL / min for 2 minutes; in another embodiment of the present invention, the cleaning driver transports reagent A through the cleaning head to automatically flush the air curtain baffle at a rate of 30 μL / min for 2 minutes; in yet another embodiment of the present invention, the cleaning driver transports reagent A through the cleaning head to automatically flush the air curtain baffle at a rate of 20 μL / min for 2 minutes.

[0095] The specific setting of the flow rate of reagent A in the present invention can be selected by the staff according to the actual situation, and is not specifically limited in the present invention.

[0096] In the present invention, by setting the reagent A to the above flow rate to flush the air curtain baffle, the air curtain baffle can be cleaned in a short time, so as to have a better flushing effect and improve the cleaning efficiency of the air curtain baffle.

[0097] Further, in step S3, the controlling reagent B to automatically flush the air curtain baffle at a certain rate for a certain period of time includes:

[0098] The cleaning drive delivers reagent B at a rate of 10 μL / min-30 μL / min through the cleaning head to automatically flush the air curtain baffle for 2 minutes.

[0099] Specifically, in one embodiment of the present invention, the cleaning driver transports reagent B through the cleaning head to automatically flush the air curtain baffle at a rate of 10 μL / min for 2 minutes; in another embodiment of the present invention, the cleaning driver transports reagent B through the cleaning head to automatically flush the air curtain baffle at a rate of 30 μL / min for 2 minutes; in yet another embodiment of the present invention, the cleaning driver transports reagent B through the cleaning head to automatically flush the air curtain baffle at a rate of 20 μL / min for 2 minutes.

[0100] The specific setting of the flow rate of reagent B in the present invention can be selected by the staff according to the actual situation, and is not specifically limited in the present invention.

[0101] In the present invention, by setting the reagent B to the above flow rate to flush the air curtain baffle, the air curtain baffle can be cleaned in a short time, so as to have a better flushing effect and improve the cleaning efficiency of the air curtain baffle.

[0102] Further, in step S4, heating and drying the air curtain baffle for a certain period of time comprises:

[0103] Control the nebulizer to start and provide atomizing gas at a flow rate of 30 to 70 psi;

[0104] Control the auxiliary heater to start, heat the temperature to 100-200°C, and heat and dry the air curtain baffle for 1 minute.

[0105] Specifically, in one embodiment of the present invention, the sprayer is controlled to start and provide atomizing gas at a flow rate of 30 psi; the auxiliary heater is controlled to start and heat the temperature to 100°C, and the air curtain baffle is heated and blown dry for 1 min; in another embodiment of the present invention, the sprayer is controlled to start and provide atomizing gas at a flow rate of 370 psi; the auxiliary heater is controlled to start and heat the temperature to 1200°C, and the air curtain baffle is heated and blown dry for 1 min; in yet another embodiment of the present invention, the sprayer is controlled to start and provide atomizing gas at a flow rate of 50 psi; the auxiliary heater is controlled to start and heat the temperature to 150°C, and the air curtain baffle is heated and blown dry for 1 min.

[0106] The specific settings of the flow rate of the atomizing gas provided by the sprayer and the heating temperature of the auxiliary heater in the present invention can be selected by the staff according to the actual situation, and are not specifically limited in the present invention.

[0107] In the present invention, the air curtain baffle is heated and blown by using the above data, thereby greatly improving the cleaning efficiency of the air curtain baffle, and the air curtain baffle can be blown dry in a short time, greatly shortening the cleaning time of the air curtain baffle.

[0108] In a specific embodiment of the present invention:

[0109] When the normal detection work of the mass spectrometer is completed, under the action of the driving force, the baffle blocks the sampling cone hole, and the controller sends the three-way valve 125 in the control instruction to control the three-way valve 125 to connect the cleaning driver 122 with the first storage part 123. Under the action of the cleaning driver 122, the reagent A in the first storage part 123 automatically flushes the air curtain baffle at a rate of 10μL / min-30μL / min for 2 minutes through the cleaning head 121. When the reagent A in the first storage part 123 automatically flushes the air curtain baffle, the controller controls the three-way valve 125 in the control instruction to control the three-way valve 125 to connect the cleaning driver 122 with the second storage part 124. Under the action of the cleaning driver 122, the reagent B in the second storage part 124 passes through the cleaning head 121 at a rate of 10μL / min-30μL / min. The washing head 121 automatically rinses the air curtain baffle for 2 minutes. When the reagent B in the second material storage part 124 automatically rinses the air curtain baffle, the generated waste liquid is discharged to the external waste liquid recovery equipment through the waste liquid discharge port 150 for recovery. At the same time, the controller sends control instructions to the sprayer 130 and the auxiliary heater 140 respectively to control the start of the sprayer 130. The sprayer 130 provides atomizing gas at a flow rate of 30 to 70 psi. The auxiliary heater 140 is synchronously controlled to start to heat the temperature in the accommodating chamber 111 to 100 to 200°C to heat and dry the air curtain baffle 112 for 1 minute. After the heating and drying of the air curtain baffle 112 is completed, the controller sends a control instruction to the controller to send a control instruction to the baffle to control the baffle to automatically return to its original position. The cleaning of the air curtain baffle in the ion source is completed, and the mass spectrometer can continue to perform detection work.

[0110] The number of devices and processing scales described here are used to simplify the description of the present invention. Applications, modifications and variations of the present invention will be obvious to those skilled in the art.

[0111] Although the embodiments of the present invention have been disclosed above, they are not limited to the applications listed in the specification and the embodiments. It can be fully applied to various fields suitable for the present invention. For those familiar with the art, additional modifications can be easily realized. Therefore, without departing from the general concept defined by the claims and equivalent scope, the present invention is not limited to the specific details and the illustrations shown and described here.

Claims

1. An automatic cleaning device for a mass spectrometer air curtain baffle, characterized in that: include: An ion source body (110) whose interior is hollow to form a receiving chamber (111), wherein an air curtain baffle (112) is arranged in the receiving chamber (111); Cleaning components (120), which are provided in at least two groups, and the two cleaning components (120) are arranged symmetrically, and the cleaning components (120) are connected to the accommodating chamber (111); as well as A controller, which is electrically or wirelessly connected to the cleaning component (120); The cleaning component (120) comprises: a cleaning head (121) which is fixedly mounted on the ion source body (110), and an output port of the cleaning head (121) is in communication with the accommodating chamber (111); A cleaning driver (122), the output end of which is connected to the cleaning head (121) and the cleaning head (121), and the cleaning driver (122) is electrically or wirelessly connected to the controller; a first material storage member (123), which is connected to an input end of the cleaning drive (122); and A second material storage member (124) which is connected to an input end of the cleaning drive (122); The first material storage member (123) and the second material storage member (124) both store cleaning solvents. Under the control of the controller, the cleaning driver (122) respectively transports the cleaning solvents in the first material storage member (123) and the second material storage member (124) through the cleaning head (121) to clean the air curtain baffle (112). The cleaning component (120) further comprises: a three-way valve (125), wherein the three-way valve (125) is electrically or wirelessly connected to the controller, and an output end of the three-way valve (125) is connected to an input end of the cleaning driver (122), a first input end of the three-way valve (125) is connected to the first material storage member (123), and a second input end of the three-way valve (125) is connected to the second material storage member (124). It also includes: a sprayer (130) fixedly installed in the accommodating cavity (111); No less than two auxiliary heaters (140) are arranged, and the auxiliary heaters (140) are fixedly installed in the accommodating cavity (111); and a baffle, which is movably arranged in the accommodating cavity (111); The sprayer (130) and the auxiliary heater (140) are both electrically or wirelessly connected to the controller.

2. The automatic cleaning device for the air curtain baffle of a mass spectrometer according to claim 1, characterized in that: The cleaning solvents stored in the first material storage member (123) and the second material storage member (124) are different.

3. The automatic cleaning device for the air curtain baffle of a mass spectrometer according to claim 1, characterized in that: A temperature sensor and a temperature alarm are also arranged in the accommodating chamber (111), and the temperature sensor and the temperature alarm are both electrically or wirelessly connected to the controller. The temperature sensor is used to sense the temperature of the accommodating chamber (111). When the temperature sensor senses that the temperature in the accommodating chamber (111) is abnormal, the temperature alarm issues an abnormality alarm.

4. A method for cleaning a mass spectrometer air curtain baffle, the method being applied to an automatic cleaning device for a mass spectrometer air curtain baffle as claimed in any one of claims 1 to 3, characterized in that: The method comprises the following steps: The control baffle blocks the tapered hole of the air curtain baffle; Control reagent A to automatically flush the air curtain baffle at a certain rate for a certain period of time; Control reagent B to automatically flush the air curtain baffle at a certain rate for a certain period of time; Heat and dry the air curtain baffle for a certain period of time; The control baffle returns to its original position automatically.

5. The method for cleaning the gas curtain baffle of a mass spectrometer according to claim 4, characterized in that: The reagent A is methanol water, and the reagent B is methanol.

6. The method for cleaning the gas curtain baffle of a mass spectrometer according to claim 4, characterized in that: The controlling reagent A to automatically flush the air curtain baffle at a certain rate for a certain period of time comprises: The cleaning drive delivers reagent A at a rate of 10 μL / min-30 μL / min through the cleaning head to automatically flush the air curtain baffle for 2 minutes.

7. The method for cleaning the gas curtain baffle of a mass spectrometer according to claim 4, characterized in that: The controlling reagent B to automatically flush the air curtain baffle at a certain rate for a certain period of time comprises: The cleaning drive delivers reagent B at a rate of 10 μL / min-30 μL / min through the cleaning head to automatically flush the air curtain baffle for 2 minutes.

8. The method for cleaning the gas curtain baffle of a mass spectrometer according to claim 4, characterized in that: The step of heating and drying the air curtain baffle for a certain period of time comprises: Control the nebulizer to start and provide atomizing gas at a flow rate of 30~70psi; Control the auxiliary heater to start, heat the temperature to 100~200℃, and heat and dry the air curtain baffle for 1 minute.

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