A kind of plant-extracted fruit acid body lotion and preparation method thereof

Abstract

The present application relates to a plant-derived fruit acid body lotion and a preparation method thereof. In the present application, titanium dioxide nanoparticles loaded with superoxide dismutase are added to the body lotion, so that superoxide dismutase and nano-titanium dioxide have a synergistic effect, and its antioxidant activity can be significantly improved.

Description

Technical Field

[0001] The present application relates to the technical field of cosmetics, and in particular to a plant-based fruit acid body lotion and a preparation method thereof. Background Art

[0002] The skin is the largest organ in the human body, accounting for 5%-15% of the body weight, with a total area of ​​1.5-2 square meters. The thickness varies from person to person and from part to part, ranging from 0.5 to 4 mm. The skin covers the whole body, protecting various tissues and organs in the body from physical, mechanical, chemical and pathogenic microbial invasions. The skin has two barrier functions: on the one hand, it prevents the loss of water, electrolytes and other substances in the body, and on the other hand, it prevents the invasion of harmful substances from the outside world and maintains the stability of the human body's internal environment. It plays an important protective function physiologically. At the same time, the skin also participates in the body's metabolic process. Increased urea nitrogen content in the human body will lead to accelerated fatigue.

[0003] Skin will develop dry skin, wrinkles and pigmentation as the weather changes, age increases, and various factors such as wind and sun exposure. Generally, various cosmetics such as lotions and emulsions are used to protect the skin and reduce the above problems. With the improvement of living standards and the development of science and technology, people have higher and higher requirements for beauty and skin care products, which has promoted the rapid development of the cosmetics industry.

[0004] Body lotion is a common cosmetic product, which mainly has the functions of keeping the skin moisturized, whitening and repairing skin damage. There are many kinds of body lotions on the market, but their functions are relatively single. The addition of multifunctional body lotions will be more responsible and easy to irritate some sensitive skin; therefore, it is necessary to study a body lotion with multiple functions. Summary of the invention

[0005] In order to enable the body lotion to play the role of moisturizing, preventing wrinkles and repairing skin damage, the present application provides a plant-based fruit acid body lotion and a preparation method thereof.

[0006] In the first aspect, a plant-based fruit acid body lotion comprises the following components in proportion by mass:

[0007] 4-6 parts of glycerin, 3-5 parts of liquid paraffin, 1-3 parts of ethylhexyl palmitate, 1-3 parts of polydimethylsiloxane, 1-3 parts of glyceryl stearate, 1-3.75 parts of cetearyl alcohol, 0.5-1 parts of PEG-100 stearate, 0.3-0.6 parts of phenoxyethanol, 0.2-0.4 parts of p-hydroxyacetophenone, 0.1-0.3 parts of niacinamide, 0.1-0.3 parts of carbomer, 0.10-0.15 parts of aminomethyl propanol, 0.05-10 parts of jojoba seed oil, 0.05-10 parts of avocado tree butter, 0.05-0.15 parts of allantoin, 0.05-0.15 parts of xanthan gum, 0.005-0.015 parts of sodium hyaluronate, 0.001-0.003 parts of purslane extract, 0.01-0.06 parts of butylene glycol, 0.04-0.06 parts of ethylhexylglycerin, 0.04-0.06 parts of caprylyl glycol, 0.03-0.05 parts of lactic acid, 0.005-0.007 parts of citric acid, 0.001-0.002 parts of gluconic acid, 0.002-0.004 parts of tartaric acid, 0.01-0.02 parts of 1,3-propylene glycol, 0.08-0.1 parts of flavor, and 60-85 parts of water.

[0008] By adopting the above technical scheme, fruit acid (lactic acid, citric acid, gluconic acid and tartaric acid) is added to the body lotion in the present application, which has a good exfoliating and moisturizing effect, and can also promote the metabolism of the skin and make the skin smooth; fruit acid can also play a role in complexing heavy metal ions, which can reduce the appearance of spots. Glycerin and ethylhexylglycerol are added to the present application as moisturizers, which can play a good moisturizing effect. Liquid paraffin, ethylhexyl palmitate, and polydimethylsiloxane are added as emollients in the present application, which can keep the skin soft and smooth, and can play a role in lubricating the skin; the emollient in the present application also includes jojoba seed oil and avocado tree fruit fat, which is a plant oil, which can not only moisturize the skin, but also replace the lipids lost in the stratum corneum, reduce flaky skin, and improve the appearance of the skin, so the synergistic effect of the two types of emollients can better play a moisturizing effect. The present application also includes a variety of skin conditioning agents. The first is niacinamide, which can reduce the transport of melanin to the stratum corneum of the skin, reduce the deposition of melanin in the stratum corneum, and prevent the skin from darkening. Niacinamide can significantly reduce the area and number of brown spots on the skin, and the skin spots can be seen to be lighter in color with the naked eye; the second is allantoin, which can promote cell growth, soften keratin, and can combine with various substances to form complex salts. It has the effects of light protection, sterilization, antiseptic, analgesia, and antioxidant, and can keep the skin hydrated, moisturized and soft; the fourth is sodium hyaluronate, which has anti-wrinkle and anti-ultraviolet effects, and it can also moisturize the skin; the fifth is purslane extract, which also contains a large amount of purslane polysaccharides, which can improve the body's immune ability, and it has a strong antioxidant effect, which can delay skin aging, and the purslane extract has anti-inflammatory and anti-allergic effects, which can reduce allergic reactions caused by other components; a variety of skin conditioning agents can improve the skin's microenvironment, keep the skin moisturized, and reduce the growth of spots. The present application also includes a variety of emulsifiers, thickeners, pH adjusters, etc., which can improve the stability of the body lotion and its affinity with the skin during the preparation process, making the body lotion easy to spread on the skin while being refreshing and non-greasy.

[0009] Preferably, a plant-based fruit acid body lotion comprises, by weight, 5 parts of glycerin, 5 parts of liquid paraffin, 2 parts of ethylhexyl palmitate, 2 parts of polydimethylsiloxane, 2.75 parts of glyceryl stearate, 2 parts of cetearyl alcohol, 0.75 parts of PEG-100 stearate, 0.45 parts of phenoxyethanol, 0.3 parts of p-hydroxyacetophenone, 0.2 parts of niacinamide, 0.2 parts of carbomer, 0.12 parts of aminomethyl propanol, 5 parts of jojoba seed oil, and 0.5 parts of cholinesterase inhibitor. 5 parts of olea europaea fruit fat, 0.1 parts of allantoin, 0.1 parts of xanthan gum, 0.01 parts of sodium hyaluronate, 0.002 parts of purslane extract, 0.05 parts of butylene glycol, 0.05 parts of ethylhexylglycerin, 0.05 parts of caprylyl glycol, 0.486 parts of lactic acid, 0.006 parts of citric acid, 0.0012 parts of gluconic acid, 0.004 parts of tartaric acid, 0.012 parts of 1,3-propylene glycol, 0.099 parts of flavor, and 79.4988 parts of water.

[0010] By adopting the above technical scheme, the proportion performance of each component is further controlled in the present application, so that the body lotion can have the effects of moisturizing, anti-wrinkle, anti-aging, damage repair, anti-allergy, etc., and the body lotion can be better spread and absorbed on the skin while keeping the skin fresh.

[0011] Preferably, the method for preparing the purslane extract comprises the following steps:

[0012] After the purslane is crushed, water, cellulase and pectinase are added and mixed to perform enzymolysis. After the enzymolysis is completed, pure water is added to perform heating and pressurized extraction. After the extraction is completed, the extraction is filtered to obtain an extract; after the extract is concentrated, an extract of purslane is obtained.

[0013] By adopting the above-mentioned technical scheme, the purslane extract in the present application is first enzymatically hydrolyzed with cellulase and pectinase, which can destroy the fiber structure of purslane, thereby making the active polysaccharides and flavonoids easier to dissolve; during the extraction, further pressurization and heating can be performed to release the active substances in purslane into water, thereby increasing the content of active ingredients in the extract; in the case of a small amount added in the present application, it still has a good skin care effect.

[0014] Preferably, during the enzymatic hydrolysis process, the mass ratio of purslane powder, cellulase, pectinase and water is: 100:(0.5-0.8):(0.2-0.3):(120-180), the enzymatic hydrolysis temperature is 40-50°C, and the enzymatic hydrolysis time is 30-40 minutes; during the extraction process, the amount of water added is 5-8 times that of the purslane powder, the extraction tank is pressurized at 1.0-1.5MPa, the extraction temperature is 60-75°C, and the extraction time is 1-2h; the density of the concentrated extract is 1.05-1.08.

[0015] By adopting the above technical scheme, controlling the enzymatic hydrolysis and extraction conditions in the present application can enrich the active substances in Purslane and increase the concentration of its active substances, thereby better achieving the antioxidant, anti-inflammatory and anti-allergic effects.

[0016] Preferably, the plant-based fruit acid body lotion further comprises 0.001 to 0.005 parts of titanium dioxide nanoparticles loaded with superoxide dismutase.

[0017] By adopting the above technical solution, the superoxide dismutase SOD in the present application has a good effective scavenger of superoxide anion free radicals, and titanium dioxide has a good anti-ultraviolet effect, but the stability of SOD is relatively poor, so porous titanium dioxide is used in the present application to adsorb SOD to improve its stability. The addition of SOD and titanium dioxide in the present application can better improve the antioxidant and anti-ultraviolet effects of the body lotion.

[0018] Preferably, the method for preparing superoxide dismutase-loaded titanium dioxide nanoparticles comprises the following steps: dissolving superoxide dismutase in water, then adding porous nano-titanium dioxide thereto, vacuumizing under stirring conditions for adsorption, filtering after adsorption, and freeze-drying to obtain superoxide dismutase-loaded titanium dioxide nanoparticles.

[0019] By adopting the above technical solution, in the present application, after superoxide dismutase is dissolved in water, a pressure difference is formed inside the pores of nano-titanium dioxide under vacuum conditions, so that the superoxide dismutase can be adsorbed into the pores of titanium dioxide; in order to avoid enzyme inactivation, freeze-drying is used as the drying method in the present application.

[0020] Preferably, the concentration of superoxide dismutase in water is 0.5-1 mg / mL, the mass ratio of superoxide dismutase to porous nano-titanium dioxide is 1:(50-200), and the adsorption time is 2-3 h.

[0021] By adopting the above technical solution, the present application can control the superoxide dismutase loading amount by controlling the adsorption conditions, thereby ensuring the effect of the titanium dioxide nanoparticles loaded with superoxide dismutase.

[0022] In the second aspect, the present application provides a method for preparing a plant-based fruit acid body lotion, using the following technical solution:

[0023] A method for preparing a plant-based fruit acid body lotion comprises the following steps:

[0024] S1: According to the properties of the raw materials, they are divided into phases A, B, C, D, and E;

[0025] Phase A: 20-29 parts of water, carbomer; Phase B: 20-28 parts of water, glycerin, p-hydroxyacetophenone, allantoin, xanthan gum, sodium hyaluronate; Phase C: liquid paraffin, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, jojoba seed oil, avocado tree butter; Phase D: 20-27 parts of water, aminomethyl propanol; Phase E: phenoxyethanol, niacinamide, purslane extract , butylene glycol, ethylhexylglycerin, caprylyl glycol, lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol, essence, and 0.07-0.1 parts of water; in phase E, purslane extract, butylene glycol and 0.03-0.05 parts of water are first mixed, and then phase E is added; lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol and 0.04-0.05 parts of water are first mixed, and then phase E is added;

[0026] S2: Add the raw materials of phase A into the water phase pot, stir thoroughly to make them swell evenly, heat and keep warm, and set aside;

[0027] S3: Add phase B into the main pot, stir and heat to keep warm, set aside;

[0028] S4: Add phase C to the oil pan and heat until completely melted;

[0029] S5: Vacuum the main pot, draw the raw materials obtained in step S2 and step S4 into the main pot, control the temperature at 85℃~90℃, stir for 8~15min, circulate and homogenize at 2500~3500r / min for 2~4min, add phase D, continue stirring and turn on cooling water to cool down; cool down to 40℃-45℃, add phase E into the main pot, stir for 20~40min, take samples for testing and discharge the materials to obtain plant-based fruit acid body lotion.

[0030] By adopting the above technical scheme, in this application, the raw materials are first classified according to their properties, the water phase and the oil phase are separated, and then they are mixed and emulsified, and then the D phase adjuster is added, and finally the high temperature-intolerant E phase active substance is added, so that each phase can be fully mixed and evenly, and a homogeneous and effective body lotion can be formed.

[0031] Preferably, in step S1, in phase E, purslane extract, butylene glycol and 0.03-0.05 parts of water are first mixed and then added to phase E; lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol and 0.04-0.05 parts of water are first mixed and then added to phase E; if superoxide dismutase-loaded titanium dioxide nanoparticles are added, they are also added to phase E.

[0032] By adopting the above technical scheme, the purslane extract and fruit acid in the E phase of the present application are the main active substances in the body lotion, so their dispersibility in the body lotion will have a direct impact on the effect of the body lotion. In the present application, butylene glycol and water are first used to dissolve the purslane extract, which can make it better dispersed in the body lotion. The cultivation of fruit acid is the same. Because the superoxide dismutase titanium dioxide nanoparticles are not very resistant to high temperatures, adding them to the E phase can better protect their activity.

[0033] Preferably, in step S2, the heating temperature is 80-85°C, and the mixture is kept warm for more than 20 minutes before being drawn into the main pot; in step S3, the heating temperature is 85-95°C, and the mixture is kept warm for more than 20 minutes before being drawn into other components; in step S4, the heating temperature is 85-95°C.

[0034] By adopting the above technical solution, the temperature and insulation time are controlled in the present application, so that each phase can be fully dissolved and mixed evenly, which is beneficial to the subsequent emulsification and mixing uniformity, thereby better improving the effect of the body lotion.

[0035] In summary, the present application includes at least one of the following beneficial technical effects:

[0036] 1. In this application, by adding jojoba seed oil and avocado tree fruit fat to the body lotion, the moisturizing effect of the body lotion can be significantly improved, the skin can be nourished, and the dry and rough skin can be improved. In this application, the extract of purslane is added, which can reduce the sensitivity of the skin, improve its antioxidant and anti-inflammatory properties, and can play a good role in conditioning the skin. The fruit acid composition in this application can promote the renewal of keratin and play a role in delicate skin; the synergistic cooperation between the components can make the body lotion have multiple functions and is not easy to cause allergies.

[0037] 2. In the present application, the preparation of purslane extract adopts the process of enzymatic hydrolysis + pressure extraction, which can better extract the active ingredients in purslane, thereby improving its comprehensive effect.

[0038] 3. In the preparation method of the present application, the raw materials are grouped according to their properties, which can enable better emulsification between the components and also enable the components to be fully mixed to form a homogeneous emulsion, thereby helping to improve the overall performance of the body lotion. DETAILED DESCRIPTION

[0039] Preparation Examples 1 to 4 Preparation of Portulaca Oleracea Extract

[0040] Preparation Example 1

[0041] The dried purslane is crushed and passed through a 60-mesh sieve to obtain purslane powder; 200 g of purslane is added with 280 mL of water, 1.4 g of cellulase and 0.5 g of pectinase, and the mixture is heated to 45° C. for enzymolysis for 30 min. After the enzymolysis is completed, 1.2 L of pure water is added thereto, the mixture is heated to 70° C., pressurized to 1.0 MPa, and extracted for 1.5 h. After the extraction is completed, the mixture is filtered to obtain an extract; the extract is concentrated to a density of 1.05 to 1.08 to obtain a purslane extract.

[0042] Preparation Example 2

[0043] The dried purslane is crushed and passed through a 60-mesh sieve to obtain purslane powder; 200 g of purslane is added with 240 mL of water, 1.0 g of cellulase and 0.6 g of pectinase, and the mixture is heated to 50° C. for enzymolysis for 40 min. After the enzymolysis is completed, 1.4 L of pure water is added thereto, the mixture is heated to 75° C., pressurized to 1.5 MPa, and extracted for 1 h. After the extraction is completed, the mixture is filtered to obtain an extract; the extract is concentrated to a density of 1.05 to 1.08 to obtain a purslane extract.

[0044] Preparation Example 3

[0045] The dried purslane is crushed and passed through a 60-mesh sieve to obtain purslane powder; 200 g of purslane is added with 360 mL of water, 1.6 g of cellulase and 0.4 g of pectinase, and the mixture is heated to 45° C. for enzymolysis for 20 min. After the enzymolysis is completed, 1.0 L of pure water is added thereto, the mixture is heated to 60° C., pressurized to 1.0 MPa, and extracted for 2 h. After the extraction is completed, the mixture is filtered to obtain an extract; the extract is concentrated to a density of 1.05 to 1.08 to obtain a purslane extract.

[0046] Preparation Example 4

[0047] The dried purslane is crushed and passed through a 60-mesh sieve to obtain purslane powder; 200 g of purslane is added with 1.48 L of pure water, heated to 70° C., pressurized to 1.0 MPa, and extracted for 2 hours. After the extraction is completed, it is filtered to obtain an extract; the extract is concentrated to a density of 1.05 to 1.08 to obtain a purslane extract.

[0048] Preparation Examples 5 to 6 are preparations of titanium dioxide nanoparticles loaded with superoxide dismutase

[0049] Preparation Example 5

[0050] 80 mg of superoxide dismutase was dissolved in 80 mL of water, and then 8 g of porous nano-titanium dioxide was added thereto. Under stirring conditions, vacuum was drawn for adsorption for 2 hours. After the adsorption was completed, the mixture was filtered and freeze-dried to obtain titanium dioxide nanoparticles loaded with superoxide dismutase.

[0051] Preparation Example 6

[0052] 80 mg of superoxide dismutase was dissolved in 160 mL of water, and then 4 g of porous nano-titanium dioxide was added thereto. Under stirring conditions, vacuum was drawn for adsorption for 3 hours. After the adsorption was completed, the mixture was filtered and freeze-dried to obtain titanium dioxide nanoparticles loaded with superoxide dismutase.

[0053] Examples 1 to 3

[0054] The raw material ratios in Examples 1 to 3 are shown in Table 1:

[0055] Table 1

[0056]

[0057]

[0058] The raw material compositions in Examples 1 to 3 are shown in Table 1, and the phase separation is as follows:

[0059] Example 1 Phase separation: Phase A: 28 kg water, carbomer; Phase B: 25 kg water, glycerin, p-hydroxyacetophenone, allantoin, xanthan gum, sodium hyaluronate; Phase C: liquid paraffin, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, jojoba seed oil, avocado tree butter; Phase D: 26.3032 kg water, aminomethyl propanol; Phase E: phenoxyethanol, niacinamide, macadamia Purslane extract, butylene glycol, ethylhexylglycerin, caprylyl glycol, lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol, essence, and 0.0480 kg of water; in phase E, purslane extract, butylene glycol, and 0.03-0.05 parts of water are first mixed, and then phase E is added; lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol, and 0.0498 kg of water are first mixed, and then phase E is added;

[0060] The other phase separations of Example 2 are consistent with those of Example 1, except that the distribution of water is different:

[0061] Phase A: 27 kg of water; Phase B: 26 kg of water; Phase D: 25.103 kg of water; Phase E, fruit acid part: 0.05 kg of water; Extract part: 0.03 kg of water.

[0062] The other phase separations of Example 3 are consistent with those of Example 1, except that the distribution of water is different:

[0063] Phase A: 27 kg of water; Phase B: 26 kg of water; Phase D: 24.675 kg of water; Phase E, fruit acid part: 0.04 kg of water; Extract part: 0.05 kg of water.

[0064] The preparation steps are as follows:

[0065] S1: Add the raw materials of phase A into the water phase pot, stir thoroughly to swell evenly, heat to 85℃ and keep warm for 20min, and set aside;

[0066] S2: Add phase B into the main pot, stir and heat to 90℃ for 20 min, set aside;

[0067] S3: Add phase C into an oil pan and heat to 90°C until completely melted;

[0068] S4: evacuate the main pot, draw the raw materials obtained in step S2 and step S4 into the main pot, control the temperature at 90°C, stir for 10 minutes, circulate and homogenize at 3000r / min for 3 minutes, add phase D, continue stirring and turn on cooling water to cool down; cool down to 45°C, add phase E into the main pot, stir for 30 minutes, take samples for testing and discharge the materials to obtain the plant-based fruit acid body lotion.

[0069] Comparative Example 1

[0070] The method is basically the same as Example 1, except that jojoba seed oil is not added and avocado fruit of equal mass is used instead.

[0071] Comparative Example 2

[0072] The method is basically the same as Example 1, except that avocado oil is not added and jojoba seed oil of equal mass is used instead.

[0073] Comparative Example 3

[0074] The method is basically the same as Example 1, except that the fruit acid composition (lactic acid, citric acid, gluconic acid, and tartaric acid components) is not added.

[0075] Comparative Example 4

[0076] The same as Example 1, except that the purslane extract component (purslane extract) is not added.

[0077] Example 4

[0078] The method is basically the same as Example 1, except that the purslane extract in Preparation Example 4 is added.

[0079] The body lotions in Examples 1 to 4 and Comparative Examples 1 to 4 were subjected to the following tests.

[0080] Moisture retention test:

[0081] Use 5% glycerol as a positive control; accurately weigh the body lotion and positive control samples and place them in the same empty bottle. Then place the samples and controls in a constant temperature and humidity device at 20°C and 40% humidity. After 24 hours, weigh the samples and calculate the moisturizing rate.

[0082] Where: m t is the mass after being placed for 24 hours, m0 is the mass of the empty bottle, and m is the mass of the sample.

[0083] In the moisturizing effect evaluation: the higher the moisturizing rate, the stronger the moisturizing effect of the sample. If the 24h moisturizing rate of the sample is higher than that of the positive control, it means that it has a certain moisturizing effect.

[0084] Allergy test:

[0085] The hyaluronidase inhibition test was used for evaluation.

[0086] The body lotion was diluted to a sample mass concentration of 2%; the positive control (dipotassium glycyrrhizinate) was prepared to a mass concentration of 3%; and pure water was used as a negative control.

[0087] Set up sample groups, sample background groups, solvent groups and solvent background groups. Each group needs to set up 3 parallels. Add different reagent solutions to the four groups respectively. After standing at room temperature for 30 minutes, the color will develop. Use a UV spectrophotometer to measure the absorbance at 528nm.

[0088] Wherein: A- is the absorbance of the reaction solution without sample; B- is the absorbance of the reaction solution without sample and enzyme; C is the absorbance of the reaction solution containing sample and enzyme; D- is the absorbance of the reaction solution containing sample and no enzyme.

[0089] Evaluation criteria: If the hyaluronic acid inhibition rate of the sample is higher than that of the negative control and there is a significant difference (P < 0.05), it is considered that the test product has a certain soothing effect.

[0090] Antioxidant test:

[0091] Preparation of reference substance: Accurately weigh about 3 mg of DPPH, dissolve it in anhydrous ethanol, make up to volume in a 50 mL volumetric flask, and refrigerate it for later use (prepare it when needed, it can only be stable for 5 hours, dark blue).

[0092] Use a pipette to take 2ml of water, and then take 2ml of DPPH solution and shake thoroughly; after 30 minutes, measure the absorbance A value (Ac) at 517nm; use a pipette to take 2ml of sample solution; then take 2ml of ethanol and shake thoroughly. After 30 minutes, measure the absorbance A value (Aj) at 517nm; use a pipette to take 2ml of sample solution, and then take 2ml of DPPH solution and shake thoroughly. Let stand at room temperature for 30 minutes and measure the absorbance A value (Ai). Perform three parallel measurements to calculate the clearance rate;

[0093]

[0094] Wherein: K is the scavenging rate of the free radical scavenger on DPPH free radicals; Ai is the absorbance of the DPPH solution after adding the sample; Aj is the absorbance of the solution with only the sample added but no DPPH added; Ac is the absorbance of the solution with only DPPH added but no sample added.

[0095] The test results are shown in Table 2.

[0096] Table 2

[0097]

[0098]

[0099] From the data in Table 2, it can be seen that the body lotions in the examples and comparative examples have certain moisturizing effects, anti-allergic soothing effects and antioxidant effects. Among Examples 1 to 4, the effect of Example 3 is the best in terms of overall effects, and the effect of Example 1 is second; this may be due to the change in the proportion of the additives, but overall, Examples 1 to 4 all have good effects.

[0100] Compared with Comparative Examples 1 and 2, Example 1 mainly changes the type of plant oil in Comparative Examples 1 and 2; in terms of effect, the moisturizing effect of Comparative Examples 1 and 2 decreases significantly, and the changes in other effects are not obvious, indicating that the combination of the two plant oils can enhance the moisturizing effect of body lotion.

[0101] Compared with Comparative Example 3, Example 1 mainly does not add fruit acid substances, and its moisturizing effect and antioxidant effect are reduced to a certain extent, but its anti-allergic and soothing effect is slightly increased; this may be because fruit acid substances can cause certain allergies, but because the amount added is very small, the improvement is not obvious; however, without adding fruit acid substances, its moisturizing effect and antioxidant effect are significantly reduced, indicating that fruit acid substances have strong moisturizing and antioxidant properties.

[0102] Compared with Example 4, in Example 1, no purslane extract was added to the purslane extract. In terms of effect, its moisturizing, anti-allergic soothing and antioxidant properties were significantly reduced, indicating that although the amount of purslane extract added was not high, it could significantly improve the comprehensive performance of the body lotion.

[0103] Compared with Example 1 and Example 4, the purslane extract added in Example 4 was not enzymatically hydrolyzed, and its comprehensive performance was reduced to a certain extent. This may be because it was not enzymatically hydrolyzed, and the active substances were less than those in Example 1, so its comprehensive performance was reduced.

[0104] Embodiment 5-6

[0105] The component ratios in Examples 5 to 6 are shown in Table 3.

[0106] Table 3

[0107]

[0108]

[0109] The preparation method in Example 5 is:

[0110] The other phase separations of Example 5 are consistent with those of Example 1, except that the distribution of water is different:

[0111] Phase A: 27 kg of water; Phase B: 26 kg of water; Phase D: 24.675 kg of water; Phase E, fruit acid part: 0.04 kg of water; Extract part: 0.05 kg of water.

[0112] The preparation steps are as follows:

[0113] The preparation steps are as follows:

[0114] S1: Add the raw materials of phase A into the water phase pot, stir thoroughly to swell evenly, heat to 85℃ and keep warm for 20min, and set aside;

[0115] S2: Add phase B into the main pot, stir and heat to 85℃ for 20 min, set aside;

[0116] S3: Add phase C into a pan and heat to 95°C until completely melted;

[0117] S4: evacuate the main pot, draw the raw materials obtained in step S2 and step S4 into the main pot, control the temperature at 85°C, stir for 15 minutes, circulate and homogenize at 3500r / min for 2 minutes, add phase D, continue stirring and turn on cooling water to cool down; cool to 40°C, add phase E into the main pot, stir for 30 minutes, take samples for testing and discharge the materials to obtain the plant-based fruit acid body lotion.

[0118] The preparation method in Example 6 is as follows:

[0119] Phase A: 27 kg of water; Phase B: 26 kg of water; Phase D: 25.103 kg of water; Phase E, fruit acid part: 0.05 kg of water; Extract part: 0.03 kg of water.

[0120] The preparation steps are as follows:

[0121] S1: Add the raw materials of phase A into the water phase pot, stir thoroughly to make them swell evenly, heat to 80℃ and keep warm for 20min, and set aside;

[0122] S2: Add phase B into the main pot, stir and heat to 95℃ for 20 min, set aside;

[0123] S3: Add phase C into a pan and heat to 95°C until completely melted;

[0124] S4: evacuate the main pot, draw the raw materials obtained in step S2 and step S4 into the main pot, control the temperature at 90°C, stir for 8 minutes, circulate and homogenize at 2500r / min for 4 minutes, add phase D, continue stirring and turn on cooling water to cool down; cool down to 40°C, add phase E into the main pot, stir for 30 minutes, take samples for testing and discharge the materials to obtain the plant-based fruit acid body lotion.

[0125] The body lotions in Examples 6 and 7 were tested for moisturizing, anti-allergic soothing and antioxidant properties, and the results are shown in Table 4.

[0126] Table 4

[0127]

[0128]

[0129] In Examples 5 and 6, the product formula and method parameters are mainly modified. From the performance point of view, the comprehensive performance will fluctuate to a certain extent, but the overall effect is maintained at a relatively good level.

[0130] Example 7

[0131] The method is basically the same as Example 1, except that, on the basis of Example 1, 0.004 kg of titanium dioxide nanoparticles loaded with superoxide dismutase (Preparation Example 5) is added to phase E.

[0132] Example 8

[0133] The method is basically the same as Example 3, except that, on the basis of Example 3, 0.003 kg of titanium dioxide nanoparticles loaded with superoxide dismutase (Preparation Example 6) is added to phase E.

[0134] Example 9

[0135] The method is basically the same as Example 5, except that, on the basis of Example 5, 0.001 kg of titanium dioxide nanoparticles loaded with superoxide dismutase (Preparation Example 5) is added to phase E.

[0136] Example 10

[0137] The method is basically the same as Example 6, except that, on the basis of Example 6, 0.005 kg of titanium dioxide nanoparticles loaded with superoxide dismutase (Preparation Example 5) is added to phase E.

[0138] Embodiment 11

[0139] The process is basically the same as Example 7, except that 0.004 kg of titanium dioxide nanoparticles are added to the E phase.

[0140] Example 12

[0141] The method is basically the same as Example 7, except that 0.0004 kg of superoxide dismutase is added to phase E.

[0142] The body lotions prepared in Examples 7 to 10 were tested for performance, and the results are shown in Table 5.

[0143] Table 5

[0144]

[0145]

[0146] From the data in Table 5, it can be seen from the data in Examples 6 to 10 that, compared with the titanium dioxide nanoparticles loaded with superoxide dismutase not added, the antioxidant effect is significantly improved, and the improvement of the moisturizing rate and the hyaluronidase inhibition rate is not obvious, indicating that the addition of titanium dioxide nanoparticles loaded with superoxide dismutase can significantly improve its antioxidant performance.

[0147] It can be seen from the data in Examples 11 and 12 that the antioxidant performance of porous titanium dioxide nanoparticles is only slightly improved by adding only porous titanium dioxide nanoparticles, and the antioxidant effect of superoxide dismutase is also improved to a relatively small extent by adding only superoxide dismutase. This may be because the uncoated superoxide dismutase in the body lotion is easy to react with other substances or is not stable enough, resulting in reduced activity, and thus the antioxidant effect is not significantly improved; it may also be that superoxide dismutase and nano-titanium dioxide have a synergistic effect, thereby significantly improving its antioxidant activity.

[0148] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A plant-derived fruit acid body lotion, characterized in that: The composition comprises the following components in parts by weight: 4-6 parts of glycerin, 3-5 parts of liquid paraffin, 1-3 parts of ethylhexyl palmitate, 1-3 parts of polydimethylsiloxane, 1-3.75 parts of glyceryl stearate, 1-3 parts of cetearyl alcohol, 0.5-1 parts of PEG-100 stearate, 0.3-0.6 parts of phenoxyethanol, 0.2-0.4 parts of p-hydroxyacetophenone, 0.1-0.3 parts of niacinamide, 0.1-0.3 parts of carbomer, 0.10-0.15 parts of aminomethyl propanol, 0.05-10 parts of jojoba seed oil, 0.05-10 parts of avocado tree butter, 0.05-0.15 parts of allantoin, yellow 0.05-0.15 parts of original gum, 0.005-0.015 parts of sodium hyaluronate, 0.001-0.003 parts of purslane extract, 0.01-0.06 parts of butylene glycol, 0.04-0.06 parts of ethylhexylglycerin, 0.04-0.06 parts of caprylyl glycol, 0.03-0.05 parts of lactic acid, 0.005-0.007 parts of citric acid, 0.001-0.002 parts of gluconic acid, 0.002-0.004 parts of tartaric acid, 0.01-0.02 parts of 1,3-propylene glycol, 0.08-0.1 parts of flavor, 60-85 parts of water; The plant-based fruit acid body lotion further comprises 0.001 to 0.005 parts of titanium dioxide nanoparticles loaded with superoxide dismutase; The method for preparing superoxide dismutase-loaded titanium dioxide nanoparticles comprises the following steps: dissolving superoxide dismutase in water, then adding porous nano-titanium dioxide thereto, vacuumizing under stirring conditions for adsorption, filtering after adsorption, and freeze-drying to obtain superoxide dismutase-loaded titanium dioxide nanoparticles; The concentration of superoxide dismutase in water is 0.5-1 mg / mL, the mass ratio of superoxide dismutase to porous nano-titanium dioxide is 1:(50-200), and the adsorption time is 2-3 hours.

2. The plant extract fruit acid body lotion according to claim 1, characterized in that: According to the mass ratio, 5 parts of glycerin, 5 parts of liquid paraffin, 2 parts of ethylhexyl palmitate, 2 parts of polydimethylsiloxane, 2.75 parts of glyceryl stearate, 2 parts of cetearyl alcohol, 0.75 parts of PEG-100 stearate, 0.45 parts of phenoxyethanol, 0.3 parts of p-hydroxyacetophenone, 0.2 parts of niacinamide, 0.2 parts of carbomer, 0.12 parts of aminomethyl propanol, 5 parts of jojoba seed oil, 5 parts of avocado tree butter, urea 0.1 part of cystine, 0.1 part of xanthan gum, 0.01 part of sodium hyaluronate, 0.002 parts of purslane extract, 0.05 parts of butylene glycol, 0.05 parts of ethylhexylglycerin, 0.05 parts of caprylyl glycol, 0.0486 parts of lactic acid, 0.006 parts of citric acid, 0.0012 parts of gluconic acid, 0.004 parts of tartaric acid, 0.012 parts of 1,3-propylene glycol, 0.099 parts of flavor, and 79.4988 parts of water.

3. The plant-based fruit acid body lotion according to claim 1, characterized in that: The preparation method of the purslane extract comprises the following steps: After the purslane is crushed, water, cellulase and pectinase are added and mixed to perform enzymolysis. After the enzymolysis is completed, pure water is added to perform heating and pressurized extraction. After the extraction is completed, the extraction is filtered to obtain an extract; after the extract is concentrated, an extract of purslane is obtained.

4. The plant-based fruit acid body lotion according to claim 3, characterized in that: During the enzymatic hydrolysis process, the mass ratio of purslane powder, cellulase, pectinase and water is: 100:(0.5-0.8):(0.2-0.3):(120-180), the enzymatic hydrolysis temperature is 40-50°C, and the enzymatic hydrolysis time is 30-40 minutes; during the extraction process, the amount of water added is 5-8 times the mass of the purslane powder, the extraction tank is pressurized at 1.0-1.5MPa, the extraction temperature is 60-75°C, and the extraction time is 1-2h; and the density of the concentrated extract is 1.05-1.08g / mL.

5. A method for preparing the plant-based fruit acid body lotion according to any one of claims 1 to 4, comprising the following steps: S1: According to the properties of the raw materials, they are divided into phases A, B, C, D, and E; Phase A: 20-29 parts of water, carbomer; Phase B: 20-28 parts of water, glycerin, p-hydroxyacetophenone, allantoin, xanthan gum, sodium hyaluronate; Phase C: liquid paraffin, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, jojoba seed oil, avocado tree butter; Phase D: 20-27 parts of water, aminomethyl propanol; Phase E: phenoxyethanol, niacinamide, purslane extract, butylene glycol, ethylhexylglycerin, caprylyl glycol, lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol, fragrance, water 0.07~ 0.1 part and titanium dioxide nanoparticles loaded with superoxide dismutase; the E phase is prepared by the following steps: purslane extract, butylene glycol and 0.03-0.05 part of water are mixed to obtain a mixed solution I; lactic acid, citric acid, gluconic acid, tartaric acid, 1,3-propylene glycol and 0.04-0.05 part of water are mixed to obtain a mixed solution II; phenoxyethanol, niacinamide, ethylhexylglycerin, caprylyl glycol, essence and titanium dioxide nanoparticles loaded with superoxide dismutase are mixed, added to the mixed solution I, stirred, and then added to the mixed solution II, and stirred to obtain the E phase; S2: Add the raw materials of phase A into the water phase pot, stir thoroughly to make them swell evenly, heat and keep warm, and set aside; S3: Add phase B into the main pot, stir and heat to keep warm, set aside; S4: Add phase C to the oil pan and heat until completely melted; S5: Vacuum the main pot, draw the raw materials obtained in step S2 and step S4 into the main pot, control the temperature at 85℃~90℃, stir for 8~15min, circulate and homogenize at 2500~3500r / min for 2~4min, add phase D, continue stirring and turn on cooling water to cool down; cool down to 40℃-45℃, add phase E into the main pot, stir for 20~40min, take samples for testing and discharge the materials to obtain the plant-based fruit acid body lotion.

6. The method for preparing the plant-based fruit acid body lotion according to claim 5, characterized in that: In step S2, the heating temperature is 80-85°C, and the main pot can be pumped in after being kept warm for more than 20 minutes; in step S3, the heating temperature is 85-95°C, and other components can be pumped in after being kept warm for more than 20 minutes; in step S4, the heating temperature is 85-95°C.

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