A device and method for detecting axial focal region temperature distribution by a lateral probe

Abstract

The application discloses a device and method for realizing axial focal region temperature distribution detection through a lateral probe, and the device comprises a temperature measurement module, an imaging ultrasonic module, a lateral imaging probe, a distance measurement module and a position control module; the imaging ultrasonic module sends an electric pulse signal to the lateral imaging probe, and obtains an ultrasonic image and ultrasonic radio frequency data through the lateral imaging probe; the axis of the lateral imaging probe and the axis of a focused ultrasonic transducer always intersect; the temperature measurement module controls the lateral imaging probe to cyclically scan a temperature measurement ROI region through the position control module; and the distance measurement module is used for obtaining a mapping focal point depth D of the temperature measurement ROI region in the field of view of the lateral imaging probe. The application can solve the problem that the ultrasonic temperature measurement method cannot be applied due to the fact that the imaging ultrasonic probe and the transducer are coaxially designed, the ultrasonic radio frequency data are disturbed by a false image, and two-dimensional or three-dimensional temperature distribution detection of an axial focal region can be realized.

Description

TECHNICAL FIELD

[0001] The present application relates to a device and method for detecting temperature distribution of axial focal region by lateral probe, belonging to the field of biomedical instruments and equipment. BACKGROUND

[0002] Focused ultrasound is a kind of non-invasive treatment technology, which realizes the treatment by emitting ultrasound waves from the outside of the body to the inside of the body and converging into a focal region at a specific position, so as to produce a thermal effect on the focal region and the nearby tissue.

[0003] Since focused ultrasound mainly plays a therapeutic role by heating the tissue, temperature measurement of the focal region and the nearby tissue is beneficial to the implementation of focused ultrasound technology, and temperature measurement is also the basis for further ultrasound dose control of focused ultrasound. In addition, for the treatment target area near important or sensitive organs, measuring the temperature of the focal region and the nearby tissue also provides a means to ensure the safety of the implementation process of focused ultrasound.

[0004] Patent ZL201710876349.5 discloses an ultrasonic method for measuring temperature changes of biological tissue based on thermal expansion and gating algorithm, which can be used to measure the temperature of the focal region and the nearby tissue, but due to the design of common focused ultrasound equipment, the method will be affected by artifacts in actual scenarios, resulting in temperature measurement failure. The common focused ultrasound equipment on the market usually includes an imaging ultrasound probe and a transducer device for emitting focused ultrasound. The imaging ultrasound probe is embedded in the center opening of the transducer. This structure design causes the imaging ultrasound probe to be disturbed by artifacts caused by inter-structure reflection during imaging, and cannot output effective ultrasonic radio frequency data for temperature measurement calculation.

[0005] Therefore, a device and method capable of solving the artifact interference are needed to successfully apply the above-mentioned ultrasonic temperature measurement method in actual engineering equipment. SUMMARY

[0006] The purpose of the present application is to provide a device and method for detecting temperature distribution of axial focal region by lateral probe, which can solve the problem that the ultrasonic temperature measurement method cannot be applied due to the artifact interference of ultrasonic radio frequency data caused by the coaxial design of the imaging ultrasound probe and the transducer, and can realize two-dimensional or three-dimensional temperature distribution detection of the axial focal region.

[0007] To achieve the above-mentioned purpose, the technical solutions adopted by the present application are as follows:

[0008] On the one hand, the present application provides a device for detecting temperature distribution of axial focal region by lateral probe, which comprises a temperature measurement module, an imaging ultrasound module, a lateral imaging probe, a distance measurement module, a position control module,

[0009] The imaging ultrasound module is connected to the temperature measurement module and the lateral imaging probe. The imaging ultrasound module sends an electrical pulse signal to the lateral imaging probe and obtains ultrasound images and ultrasound radio frequency data through the lateral imaging probe.

[0010] The lateral imaging probe is mounted on the position control module, and its axis always intersects with the axis of the focused ultrasound transducer. The position control module drives the lateral imaging probe to move, and the movement allows the imaging field of the lateral imaging probe to traverse the temperature measurement ROI area.

[0011] The position control module is connected to the temperature measurement module, and the temperature measurement module controls the lateral imaging probe to perform cyclic scanning of the temperature measurement ROI area through the position control module;

[0012] The ranging module is connected to the temperature measuring module. The ranging module is used to obtain the mapping focal depth D of the temperature measuring ROI region within the field of view of the lateral imaging probe, and transmit the mapping focal depth D to the temperature measuring module.

[0013] Furthermore, the ranging module includes a ranging processing unit and a capacitive grating electronic rangefinder, used to measure the distance from the intersection point of the focused ultrasonic transducer axis and the lateral imaging probe axis to the frontmost face of the lateral imaging probe transducer, i.e., the mapped focal depth D. The ranging processing unit internally stores a distance compensation value, which is the distance between the focused ultrasonic transducer axis and the front face of the lateral imaging probe when the lateral imaging probe is in its initial state.

[0014] Furthermore, the position control module includes a parallel movement mechanism, which drives the lateral imaging probe to move up and down along the axis of the focused ultrasonic transducer via a support. Based on this structure, the method steps for the ranging module to obtain the mapped focal depth D include:

[0015] (1) The movement distance of the lateral imaging probe along its axis is measured by the capacitive grating electronic rangefinder;

[0016] (2) The moving distance and the distance compensation value are added together to obtain the mapping focus depth D.

[0017] Alternatively, the position control module may include a fan-shaped rotation mechanism located at the tail end of the bracket for mounting the lateral imaging probe, which drives the front end of the lateral imaging probe to perform a fan-shaped rotational motion. Based on this structural form, the ranging module further includes an angle sensor used to measure the deflection angle of the lateral imaging probe; the method steps for the ranging module to obtain the mapping focal depth D include:

[0018] (1) Measure the distance the lateral imaging probe moves along its axis using a capacitive grating electronic rangefinder;

[0019] (2) Measure the deflection angle using an angle sensor;

[0020] (3) Based on the geometric relationship, the distance compensation value and the deflection angle are calculated and then added to the moving distance to obtain the mapping focus depth D.

[0021] Furthermore, the temperature measurement module includes a temperature processing unit electrically connected to the device for controlling the device. The temperature processing unit internally contains an ultrasonic temperature measurement method based on ultrasonic radio frequency data. The temperature processing unit calculates the mapped (projected) area of ​​the temperature measurement ROI within the field of view of the lateral imaging probe based on the relative geometric relationship between the focusing transducer and the lateral imaging probe. This geometric relationship is determined by the actual structural design. The temperature processing unit calculates the ultrasonic radio frequency data acquisition boundary (hereinafter referred to as the acquisition boundary) based on the mapped area. The acquisition boundary is used to select the range of ultrasonic radio frequency data to be acquired. To ensure that the temperature measurement ROI can obtain a complete temperature distribution and higher temperature measurement accuracy, the acquisition boundary usually adds a certain boundary threshold to the mapped area; this threshold is usually set according to the actual situation.

[0022] Furthermore, the temperature measurement processing unit transmits the mapping focal depth and acquisition boundary to the imaging ultrasound module.

[0023] Furthermore, the imaging ultrasound module crops the entire ultrasound radio frequency data according to the mapping focal depth and acquisition boundary to obtain radio frequency data of the acquisition area.

[0024] Furthermore, the imaging ultrasound module transmits the radio frequency data of the acquisition area to the temperature measurement module. The reason this invention requires selecting the acquisition boundary, rather than transmitting all the ultrasound radio frequency data of the entire ultrasound image to the temperature measurement module, is to reduce the data bandwidth pressure between the temperature measurement module and the imaging ultrasound module, thereby increasing the data transmission frequency and achieving high frame rate ultrasound temperature measurement. In practical embodiments, if sufficient bandwidth margin is available, data clipping can be omitted; a larger radio frequency data range is beneficial for improving the accuracy of ultrasound temperature measurement.

[0025] Furthermore, the position control module controls the lateral imaging probe to perform cyclic scanning of the temperature measurement ROI area, thereby obtaining multiple sets of mapped area temperature data that can cover the entire ROI area. The frequency and accuracy of the cyclic scanning are determined according to actual needs.

[0026] Furthermore, the temperature processing unit constructs the temperature distribution of the entire temperature measurement ROI region based on the geometric relationship between the mapping region and the temperature measurement ROI region by cyclically scanning all the temperature data of the mapped region.

[0027] Furthermore, when a new set of mapped region temperature data is obtained, the temperature processing unit quickly updates the data at the corresponding position in the temperature distribution of the temperature measurement ROI region.

[0028] It should be noted that in practical embodiments, for non-phased array focused ultrasound devices, when the target position changes during treatment, the relative position of the lateral imaging probe and the focused ultrasound transducer will change, and the mapped focal depth will also change accordingly. On the other hand, during treatment, the lateral imaging probe needs to be in contact with the human skin, and is affected by physiological cycle movements such as breathing, which will also cause the mapped focal depth to change. Considering both of these factors, in practical embodiments:

[0029] 1) The measurement frequency of the distance measuring module for the depth of the mapped focus should be greater than the frequency of the human physiological movement cycle;

[0030] 2) The processor should transmit the latest acquired mapping focus depth to the temperature measurement module in real time; more preferably, the latest data should only be acquired through the ranging module when it is necessary to transmit the mapping focus depth to the temperature measurement module. This method can maintain the periodic characteristics of physiological cycle movement to the greatest extent, and can further align the periodic data through methods such as respiratory gating.

[0031] 3) Another way to deal with physiological cycle movements is to ensure that each measurement of the depth of the mapped focus by the ranging module occurs at the same moment in the physiological movement cycle. This cycle data can be set according to actual measurements of different human bodies.

[0032] In one scenario, the temperature-measuring ROI is three-dimensional. In this embodiment, the mapping region is a two-dimensional region.

[0033] In another scenario, the temperature-measuring ROI is two-dimensional, representing an axial section of the focal domain of the focused ultrasound transducer. It may also include the distribution area of ​​nearby tissue within the plane of the focal domain's axial section. Because the focal domain of a focused ultrasound transducer is typically an axis-symmetric ellipsoid, for ease of design and calculation, in this embodiment, an axial section of the focal domain perpendicular to the axis of the lateral imaging probe is usually chosen as the temperature-measuring ROI. In this embodiment, the mapping area is transformed from two-dimensional to one-dimensional; that is, the temperature-measuring ROI is mapped as a line segment within the lateral imaging probe's field of view.

[0034] On the other hand, the present invention also provides a method for detecting axial focal zone temperature distribution using a lateral probe, comprising the following steps:

[0035] Step 100: Select the temperature measurement ROI area;

[0036] Step 101: Calculate the number of layers c that need to be scanned to completely cover the ROI region;

[0037] Step 102: Move the lateral imaging probe to the nth scanning layer using the position control module;

[0038] Step 103, calculate the mapping region S of the nth scan layer. n ;

[0039] Step 104, calculate the acquisition boundary A of the nth scan layer. n ;

[0040] Step 105: Measure the distance X that the lateral imaging probe moves along its axis using the ranging module;

[0041] Step 106, calculate the mapping focus depth D;

[0042] Step 107, based on D and A n Radio frequency data (RFA) of the acquisition area was selected from the ultrasonic radio frequency data of the lateral imaging probe. n ;

[0043] Step 108, the temperature measurement module according to RFA n Calculate A n Temperature data of the region TA n ;

[0044] Step 109, from TA n S was selected from n Regional temperature data TS n ;

[0045] Step 110: Scan sequentially to obtain group c temperature data {TS} i};

[0046] Step 111: Reconstruct the three-dimensional temperature distribution {tempT(x,y,z)} based on the temperature data of group c;

[0047] Step 112: Based on the coordinates of the temperature measurement ROI region and {tempT(x,y,z)}, reconstruct the temperature distribution {T(x,y,z)} of the temperature measurement ROI region.

[0048] Furthermore, the ranging module is first set to the zero position, and the axis of the lateral imaging probe passes through the focal point of the focused ultrasonic transducer. The compensation distance from the front end of the lateral imaging probe to the focal point is denoted as... The angle between the perpendicular line from the axis of the lateral imaging probe to the axis of the focused ultrasound transducer is denoted as α.

[0049] Then, the temperature measurement ROI area is set as a cube aligned with the axes of the focused ultrasound probe, with height denoted as H, length as L, and width as W; the step value for the lateral imaging probe to move up and down for scanning is set to... The number of scanning layers c is calculated according to formula (1); the mapping area of ​​the temperature measurement ROI region in the field of view of the lateral imaging probe, the mapping area of ​​each layer has the same size, the length is L, the width is W0, and the mapping area S n Let it be S n (L, W0); Calculate according to formula (2):

[0050] (1)

[0051] (2);

[0052] Then calculate the depth of the mapped focus D according to formula (4):

[0053] (4).

[0054] Furthermore, the ranging module is first set to the zero position, and the axis of the lateral imaging probe passes through the focal point of the focused ultrasonic transducer. The compensation distance from the front end of the lateral imaging probe to the focal point is denoted as... The angle between the perpendicular line from the axis of the lateral imaging probe to the axis of the focused ultrasound transducer is denoted as α.

[0055] Then, the temperature measurement ROI area is set as a cube with the axes of the focused ultrasound probe aligned, with height denoted as H, length denoted as L, and width denoted as W; H1 is the vertical distance from the focal point to the upper plane of the temperature measurement ROI area, H2 is the vertical distance from the focal point to the lower plane of the temperature measurement ROI area, and the required sector angle φ for covering the temperature measurement ROI area is calculated by formula (5); the step angle of the lateral imaging probe sector scan is set as... The number of scan layers c is calculated according to formula (6); refer to Figure 5 The temperature measurement ROI is mapped to the field of view of the lateral imaging probe. The length of the mapped region in each layer is the same (L), but the width is different. The width of the nth layer is denoted as W. n Mapping region S n Let it be S n (L, W) n ), W n Calculate according to formula (7):

[0056] (5)

[0057] In the formula, PL is the length from the front end to the rear end of the lateral imaging probe;

[0058] (6)

[0059] (7)

[0060] The depth of the mapped focus, D, is calculated according to formula (8):

[0061] (8).

[0062] Furthermore, a boundary threshold is set to increase the sampling boundary. : Let ∆b be the threshold for increasing length and ∆b be the threshold for increasing width. The acquisition boundary An is calculated according to formula (3):

[0063] (3);

[0064] Then the imaging ultrasound module determines the mapping focal depth D and the acquisition boundary A. n Radio frequency data (RFA) of the acquisition area was selected from the ultrasonic radio frequency data of the lateral imaging probe. n The data is then transmitted to the temperature measurement module; the temperature measurement module uses a temperature measurement algorithm to analyze the RFA. n Calculated as temperature data TA n Then, according to formula (3), from TA n Select S n Regional temperature data TS n ;

[0065] After completing the temperature data measurement for the current layer, the temperature measurement module adjusts the lateral imaging probe to the (n+1)th scanning layer via the position control module, and performs the above calculation steps to obtain the temperature data TS. n+1 ; Complete the scanning of layer c sequentially to obtain group c temperature data {TS i}; Based on the inter-slice step value via {TS i The three-dimensional temperature distribution {tempT(x,y,z)} is reconstructed; based on the coordinates of the temperature measurement ROI region, the temperature distribution {T(x,y,z)} of the temperature measurement ROI region is selected from {tempT(x,y,z)}.

[0066] The beneficial effects of the present invention are as follows: The device and method provided by the present invention for detecting the temperature distribution in the axial focal region through a lateral probe can solve the problem that artifacts caused by the coaxial design of the imaging ultrasonic probe and transducer interfere with the ultrasonic radio frequency data, making the ultrasonic temperature measurement method unusable. It can realize the detection of two-dimensional or three-dimensional temperature distribution in the axial focal region.

[0067] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0068] Figure 1 This is a schematic diagram of the architecture of an axial temperature measurement device achieved through a lateral probe;

[0069] In the diagram: 1 is the position control module, 2 is the ranging module, 3 is the lateral imaging probe, 31 is the temperature measurement module, and 32 is the imaging ultrasound module.

[0070] Figure 2 This is a flowchart illustrating the implementation of the temperature measurement method of the present invention.

[0071] Figure 3 This is a partial structural schematic diagram of one embodiment;

[0072] In the diagram: 1 is the position control module, 4 is the focused ultrasound transducer, 5 is a schematic diagram of the focused ultrasound transducer axis, 6 is a schematic diagram of the lateral imaging probe axis, 7 is a schematic diagram of the focused ultrasound transducer focal zone, 8 is a schematic diagram of the temperature measurement ROI area, 12 is a schematic diagram of the angle α between the perpendicular line from the lateral imaging probe axis to the focused ultrasound transducer axis, 18 is a schematic diagram of the initial zero position of the ranging module, and 19 is the distance compensation value of the ranging module. The illustration.

[0073] Figure 4 yes Figure 3 Schematic diagram of layered scanning of the temperature measurement ROI region in the embodiment shown;

[0074] In the diagram: 13 is a schematic of the mapping area.

[0075] Figure 5 This is a schematic diagram of the mapping area and acquisition boundary, where (a) is the mapping area S of the ROI region in the field of view of the lateral imaging probe. n The diagram shows that (b) represents the mapping region S. n and the acquisition boundary A n The illustration;

[0076] In the figure: 14 is a schematic diagram of the acquisition boundary, 15 is a schematic diagram of the mapping focus, 16 is a schematic diagram of the mapping focus depth D, and 17 is a schematic diagram of the field of view of the lateral imaging probe.

[0077] Figure 6 This is a schematic diagram illustrating the process of reconstructing the temperature distribution within the temperature measurement ROI region.

[0078] Figure 7 This is a partial structural schematic diagram of another embodiment;

[0079] In the diagram: 9 represents the sector-shaped rotating mechanism.

[0080] Figure 8 yes Figure 7 Schematic diagram of layered scanning of the temperature measurement ROI region in the embodiment shown;

[0081] In the figure: 20 is the sector angle φ required for the lateral imaging probe to cover the temperature measurement ROI area; 21 is the length PL from the front face of the lateral imaging probe to the rotating shaft of the sector moving mechanical device; H1 is the vertical distance from the focal point to the upper plane of the temperature measurement ROI area; and H2 is the vertical distance from the focal point to the lower plane of the temperature measurement ROI area. Detailed Implementation

[0082] The present invention will now be described in detail with reference to the accompanying drawings and specific embodiments.

[0083] like Figure 1 The diagram illustrates the architecture of one embodiment of the present invention. In this embodiment, the device proposed by the present invention includes a temperature measurement module, an imaging ultrasound module, a lateral imaging probe, a ranging module, and a position control module.

[0084] The ranging module is connected to the temperature measurement module. The ranging module is used to obtain the mapped focal depth D of the temperature measurement ROI region within the field of view of the lateral imaging probe, and transmits the mapped focal depth D to the temperature measurement module.

[0085] The imaging ultrasound module is connected to the temperature measurement module and the lateral imaging probe. The imaging ultrasound module sends electrical pulse signals to the lateral imaging probe, obtains ultrasound images and ultrasound radio frequency data through the lateral imaging probe, and transmits the ultrasound radio frequency data to the temperature measurement module. Here, the ultrasound radio frequency data specifically refers to RF data.

[0086] The position control module is connected to the temperature measurement module. The temperature measurement module controls the lateral imaging probe to perform cyclic scanning of the temperature measurement ROI area through the position control module.

[0087] like Figure 2 The diagram shows a flowchart of a method according to an embodiment of the present invention.

[0088] Step 100: Select the temperature measurement ROI region. In practical applications, to simplify calculations, the temperature measurement ROI region is usually selected as a regular shape, such as a cubic region symmetrical about the axis of the focused ultrasound probe.

[0089] Step 101: Calculate the number of layers c that need to be scanned to completely cover the ROI region.

[0090] Step 102: Move the lateral imaging probe to the nth scanning layer using the position control module.

[0091] Step 103, calculate the mapping region S of the nth scan layer. n .

[0092] Step 104, calculate the acquisition boundary A of the nth scan layer. n .

[0093] Step 105: The electronic rangefinder reads the distance X that the lateral imaging probe has moved.

[0094] Step 106: Calculate the mapping focus depth D.

[0095] Step 107, based on D and A n Radio frequency data (RFA) of the acquisition area was selected from the ultrasonic radio frequency data of the lateral imaging probe. n .

[0096] Step 108, the temperature measurement module according to RFA n Calculate A n Temperature data of the region TA n .

[0097] Step 109, from TA n S was selected from n Regional temperature data TS n Step 110: Scan sequentially to obtain group c temperature data {TS}. i}

[0098] Step 111: Reconstruct the three-dimensional temperature distribution {tempT(x,y,z)} based on the temperature data of group c.

[0099] Step 112: Based on the coordinates of the temperature measurement ROI region and {tempT(x,y,z)}, reconstruct the temperature distribution {T(x,y,z)} of the temperature measurement ROI region.

[0100] like Figure 3 The diagram illustrates one embodiment of a lateral imaging probe, a ranging module, and a position control module. In this embodiment, the lateral imaging probe is mounted on the ranging module, the ranging module is mounted on the position control module, the position control module is mounted on the focused ultrasound transducer, and the axis of the lateral imaging probe always intersects the axis of the focused ultrasound transducer.

[0101] In this embodiment, the position control module includes a mechanical device capable of vertical parallel movement, which drives the lateral imaging probe to move horizontally in the vertical direction, parallel to the axis of the focused ultrasonic transducer. In this embodiment, the ranging module can move back and forth on the position control module, parallel to the axis of the lateral imaging probe. The ranging module is designed as a capacitive grating sensor electronic rangefinder, achieving a measurement accuracy of 0.1 mm and a measurement frequency of 500 Hz, far exceeding the frequency of human respiratory movements. Since the lateral imaging probe is mounted on the ranging module, its back-and-forth movement along its axis drives the ranging module, thereby measuring the distance traveled by the lateral imaging probe.

[0102] like Figure 3The diagram shows the initial state of this embodiment, where the ranging module is in the zero position and the axis of the lateral imaging probe passes through the focal point (center of the focal region) of the focused ultrasonic transducer. The compensation distance from the front end of the lateral imaging probe to the focal point is denoted as... The angle between the perpendicular line from the axis of the lateral imaging probe to the axis of the focused ultrasound transducer is denoted as α.

[0103] like Figure 4 As shown, it demonstrates Figure 3 The lateral imaging probe in the illustrated embodiment scans the temperature measurement ROI region. For ease of calculation, the temperature measurement ROI region is defined as a cube aligned with the axes of the focused ultrasound probe, with height denoted as H, length denoted as L, and width denoted as W. The step value for the lateral imaging probe's vertical scanning movement is set to... The number of scan layers, c, is calculated according to formula (1). Combined with... Figure 5 The dashed box in the figure represents the mapped area of ​​the temperature measurement ROI in the field of view of the lateral imaging probe. The mapped area of ​​each layer has the same size, with a length of L and a width of W0. The mapped area S n Let it be S n (L, W0). Calculate according to formula (2).

[0104] Formula (1)

[0105] Formula (2)

[0106] Set the boundary threshold for increasing the acquisition boundary. : The threshold is increased along the length direction. The threshold value is increased in the width direction, and the acquisition boundary An is calculated according to formula (3).

[0107] Formula (3)

[0108] refer to Figure 3 and Figure 5 The temperature measurement module measures the moving distance X of the lateral imaging probe through the ranging module, and calculates the mapping focal depth D according to formula (4). In this embodiment, the mapping focal depth D is the acquisition boundary A. n The center point.

[0109] Formula (4)

[0110] refer to Figure 5 (b) The imaging ultrasound module determines the focal depth D and the acquisition boundary A based on the mapping focal depth D. n Radio frequency data (RFA) of the acquisition area was selected from the ultrasonic radio frequency data of the lateral imaging probe. n And transmit it to the temperature measurement module.

[0111] refer to Figure 6 The temperature measurement module uses a temperature measurement algorithm to measure the RFA. n Calculated as temperature data TA n The temperature measurement algorithm used in this embodiment is the ultrasonic temperature measurement method disclosed in patent ZL201710876349.5. According to formula (3), from TA n Select S n Regional temperature data TS n .

[0112] After completing the temperature data measurement for the current layer, the temperature measurement module adjusts the lateral imaging probe to the (n+1)th scanning layer via the position control module, and performs the above calculation steps to obtain the temperature data TS. n+1 The scan of layer c was completed sequentially, yielding group c of temperature data {TS}. i Based on the inter-slice step value via {TS i The three-dimensional temperature distribution {tempT(x,y,z)} is reconstructed, as follows: Figure 6 As shown in (c). Based on the coordinates of the temperature measurement ROI region, the temperature distribution {T(x,y,z)} of the temperature measurement ROI region is selected from {tempT(x,y,z)}, as follows. Figure 6 As shown in (d).

[0113] like Figure 7 The diagram illustrates another embodiment of the lateral imaging probe, ranging module, and position control module. In this embodiment, the tail end of the lateral imaging probe is mounted on the position control module, which is mounted on the ranging module. The ranging module is mechanically mounted to the focused ultrasound transducer, and the axis of the lateral imaging probe always intersects the axis of the focused ultrasound transducer.

[0114] In this embodiment, the position control module includes a fan-shaped rotating mechanical device that can drive the lateral imaging probe to move along the fan-shaped direction. The position control module is equipped with an angle sensor to measure the angle of the fan-shaped rotation. The ranging module is designed as a capacitive grating sensor electronic rangefinder, with a measurement accuracy of 0.1 mm and a measurement frequency of 500 Hz, far exceeding the frequency of human breathing. Since the lateral imaging probe is mounted on the ranging module via the position control module, the movement of the lateral imaging probe along its axial direction can drive the movement of the ranging module, thereby enabling the measurement of the distance traveled by the lateral imaging probe.

[0115] like Figure 7 The diagram shows the initial state of this embodiment, where the ranging module is in the zero position and the axis of the lateral imaging probe passes through the focal point (center of the focal region) of the focused ultrasonic transducer. The compensation distance from the front end of the lateral imaging probe to the focal point is denoted as... The angle between the perpendicular line from the axis of the lateral imaging probe to the axis of the focused ultrasound transducer is denoted as α.

[0116] like Figure 8 As shown, it demonstrates Figure 7 The lateral imaging probe of the illustrated embodiment scans the temperature measurement ROI area. For ease of calculation, the temperature measurement ROI area is set as a cube with the axes of the focused ultrasound probe aligned, with height denoted as H, length denoted as L, and width denoted as W. H1 is the vertical distance from the focal point to the upper plane of the temperature measurement ROI area, and H2 is the vertical distance from the focal point to the lower plane of the temperature measurement ROI area. The required sector angle φ to cover the temperature measurement ROI area is calculated by formula (5). The step angle of the lateral imaging probe sector scan is set as... The number of scan layers, c, is calculated according to formula (6). (Reference) Figure 5 The dashed boxes in the figure represent the mapped regions of the temperature measurement ROI within the field of view of the lateral imaging probe. Each layer has the same length (L) but different widths; the width of the nth layer is denoted as W. n Mapping region S n Let it be S n (L, W) n W n Calculate according to formula (7).

[0117] Formula (5)

[0118] In the formula, PL is the length from the front end to the rear end of the lateral imaging probe.

[0119] Formula (6)

[0120] Formula (7)

[0121] The mapping focus depth D is calculated according to formula (8).

[0122] Formula (8)

[0123] The subsequent temperature measurement steps in this embodiment are the same as Figure 3 The calculation methods in the illustrated embodiments are similar, and the foregoing content can be referenced.

[0124] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the above embodiments do not limit the scope of protection of the present invention in any way, and all technical solutions obtained by equivalent substitution or other means fall within the scope of protection of the present invention.

[0125] All parts not covered in this invention are the same as or can be implemented using existing technologies.

Claims

1. A device for detecting axial focal zone temperature distribution using a lateral probe, characterized in that, It includes a temperature measurement module, an imaging ultrasound module, a lateral imaging probe, a ranging module, and a position control module. The imaging ultrasound module is connected to the temperature measurement module and the lateral imaging probe. The imaging ultrasound module sends an electrical pulse signal to the lateral imaging probe and obtains ultrasound images and ultrasound radio frequency data through the lateral imaging probe. The lateral imaging probe is mounted on the position control module, and its axis always intersects with the axis of the focused ultrasound transducer. The position control module drives the lateral imaging probe to move, and the movement allows the imaging field of the lateral imaging probe to traverse the temperature measurement ROI area. The position control module is connected to the temperature measurement module, and the temperature measurement module controls the lateral imaging probe to perform cyclic scanning of the temperature measurement ROI area through the position control module; The ranging module is connected to the temperature measuring module. The ranging module is used to obtain the mapping focal depth D of the temperature measuring ROI region within the field of view of the lateral imaging probe, and transmit the mapping focal depth D to the temperature measuring module. The mapping focal depth D is the distance from the intersection point of the axis of the focused ultrasonic transducer and the axis of the lateral imaging probe to the frontmost face of the transducer of the lateral imaging probe.

2. The device for detecting axial focal zone temperature distribution using a lateral probe according to claim 1, characterized in that, The ranging module includes a ranging processing unit and a capacitive electronic rangefinder, used to measure the depth D of the mapped focus. The ranging processing unit stores a distance compensation value, which is the distance between the axis of the focused ultrasonic transducer and the front end face of the lateral imaging probe when the lateral imaging probe is in its initial state.

3. The device for detecting axial focal zone temperature distribution using a lateral probe according to claim 2, characterized in that, The position control module includes a parallel movement mechanism, which drives the lateral imaging probe to move up and down along the axis of the focused ultrasonic transducer via a bracket.

4. The device for detecting axial focal zone temperature distribution using a lateral probe according to claim 2, characterized in that, The position control module includes a fan-shaped rotation mechanism located at the tail end of the bracket for mounting the lateral imaging probe, which drives the front end of the lateral imaging probe to rotate in a fan shape.

5. The device for detecting axial focal zone temperature distribution using a lateral probe according to claim 3, characterized in that, The method steps for the ranging module to obtain the mapping focus depth D include: (1) The movement distance of the lateral imaging probe along its axis is measured by the capacitive grating electronic rangefinder; (2) The moving distance and the distance compensation value are added together to obtain the mapping focus depth D.

6. The device for detecting axial focal zone temperature distribution using a lateral probe according to claim 4, characterized in that, The ranging module further includes an angle sensor, which is used to measure the deflection angle of the lateral imaging probe; the method steps for the ranging module to obtain the mapped focal depth D include: (1) Measure the distance the lateral imaging probe moves along its axis using a capacitive grating electronic rangefinder; (2) Measure the deflection angle using an angle sensor; (3) Based on the geometric relationship, the distance compensation value and the deflection angle are calculated and then added to the moving distance to obtain the mapping focus depth D.

7. A method for detecting axial focal zone temperature distribution using a lateral probe, characterized in that... Includes the following steps: Step 100: Select the temperature measurement ROI area; Step 101: Calculate the number of layers c that need to be scanned to completely cover the ROI region; Step 102: Move the lateral imaging probe to the nth scanning layer using the position control module; Step 103, calculate the mapping region S of the nth scan layer. n ; Step 104, calculate the acquisition boundary A of the nth scan layer. n ; Step 105: Measure the distance X that the lateral imaging probe moves along its axis using the ranging module; Step 106: Calculate the mapping focal depth D, which is the distance from the intersection of the axis of the focused ultrasound transducer and the axis of the lateral imaging probe to the frontmost face of the lateral imaging probe transducer. Step 107, based on D and A n Radio frequency data (RFA) of the acquisition area was selected from the ultrasonic radio frequency data of the lateral imaging probe. n ; Step 108, the temperature measurement module according to RFA n Calculate A n Temperature data of the region TA n ; Step 109, from TA n S was selected from n Regional temperature data TS n ; Step 110: Scan sequentially to obtain group c temperature data {TS} i }; Step 111: Reconstruct the three-dimensional temperature distribution {tempT(x,y,z)} based on the temperature data of group c; Step 112: Based on the coordinates of the temperature measurement ROI region and {tempT(x,y,z)}, reconstruct the temperature distribution {T(x,y,z)} of the temperature measurement ROI region.

8. The method for detecting axial focal zone temperature distribution using a lateral probe according to claim 7, characterized in that, First, set the ranging module to the zero position, and ensure the axis of the lateral imaging probe passes through the focal point of the focused ultrasonic transducer. The compensation distance from the front face of the lateral imaging probe to the focal point is denoted as... The angle between the perpendicular line from the axis of the lateral imaging probe to the axis of the focused ultrasound transducer is denoted as α. Then, the temperature measurement ROI area is set as a cube aligned with the axes of the focused ultrasound probe, with height denoted as H, length as L, and width as W; the step value for the lateral imaging probe to move up and down for scanning is set to... The number of scanning layers c is calculated according to formula (1); the mapping area of ​​the temperature measurement ROI region in the field of view of the lateral imaging probe, the mapping area of ​​each layer has the same size, the length is L, the width is W0, and the mapping area S n Let it be S n (L, W0); W0 is calculated according to formula (2): （1） （2）； Then calculate the depth of the mapped focus D according to formula (4): （4）。 9. The method for detecting axial focal zone temperature distribution using a lateral probe according to claim 7, characterized in that, First, set the ranging module to the zero position, and ensure the axis of the lateral imaging probe passes through the focal point of the focused ultrasonic transducer. The compensation distance from the front face of the lateral imaging probe to the focal point is denoted as... The angle between the perpendicular line from the axis of the lateral imaging probe to the axis of the focused ultrasound transducer is denoted as α. Then, the temperature measurement ROI area is set as a cube with the axes of the focused ultrasound probe aligned, with height denoted as H, length denoted as L, and width denoted as W; H1 is the vertical distance from the focal point to the upper plane of the temperature measurement ROI area, H2 is the vertical distance from the focal point to the lower plane of the temperature measurement ROI area, and the required sector angle φ for covering the temperature measurement ROI area is calculated by formula (5); the step angle of the lateral imaging probe sector scan is set as... The number of scanning layers c is calculated according to formula (6); the mapping area of ​​the temperature measurement ROI region in the field of view of the lateral imaging probe, the length of the mapping area of ​​each layer is the same L, but the width is different, and the width of the nth layer is denoted as W. n Mapping region S n Let it be S n (L, W) n ), W n Calculate according to formula (7): （5） In the formula, PL is the length from the front end to the rear end of the lateral imaging probe; （6） （7） The depth of the mapped focus, D, is calculated according to formula (8): （8）。 10. A method for detecting axial focal zone temperature distribution using a lateral probe according to claim 8 or 9, characterized in that, Set the boundary threshold for increasing the acquisition boundary. : The threshold is increased along the length direction. The threshold value is increased in the width direction. The acquisition boundary An is calculated according to formula (3): （3）； Then the imaging ultrasound module determines the mapping focal depth D and the acquisition boundary A. n Radio frequency data (RFA) of the acquisition area was selected from the ultrasonic radio frequency data of the lateral imaging probe. n The data is then transmitted to the temperature measurement module; the temperature measurement module uses a temperature measurement algorithm to analyze the RFA. n Calculated as temperature data TA n Then, according to formula (3), from TA n Select S n Regional temperature data TS n ; After completing the temperature data measurement for the current layer, the temperature measurement module adjusts the lateral imaging probe to the (n+1)th scanning layer via the position control module, and performs the above calculation steps to obtain the temperature data TS. n+1 ; The scan of layer c was completed sequentially, and the temperature data of group c {TS} was obtained. i }; Based on the inter-slice step value via {TS i The three-dimensional temperature distribution {tempT(x,y,z)} is reconstructed; based on the coordinates of the temperature measurement ROI region, the temperature distribution {T(x,y,z)} of the temperature measurement ROI region is selected from {tempT(x,y,z)}.

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