A multi-lumen tube for use with a circulating fluid to cool an ultrasonic thrombolytic catheter transducer

Abstract

The present application relates to a kind of multi-cavity tube that can be used to cool ultrasonic thrombolytic catheter transducer with circulating liquid, comprising main pipeline, the central part of main pipeline is main cavity, and the tube wall of main pipeline is provided with drug liquid cavity and physiological saline backwater cavity;Main cavity is used for the wire through of ultrasonic transducer, and the far end of main cavity is circular, and diameter is equal to the diameter of the far end of wire, and the cross-sectional area of other positions of main cavity is greater than the cross-sectional area of wire;The outer wall of main pipeline close to far end is provided with drug liquid outlet hole, and the inner wall of main pipeline close to far end is provided with physiological saline circulation hole;Drug liquid cavity does not communicate with main cavity and physiological saline backwater cavity, and drug liquid cavity communicates with drug liquid outlet hole, and drug liquid cavity extends to the proximal end of main pipeline;Physiological saline backwater cavity communicates with main cavity by physiological saline circulation hole, and physiological saline backwater cavity extends to the proximal end of main pipeline.The product of the present application is simple in structure, and has excellent heat dissipation effect, and can avoid physiological saline flowing into human blood vessels.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of intravascular thrombus removal treatment, and relates to a multi-lumen tube capable of cooling an ultrasonic thrombolytic catheter transducer with circulating liquid. BACKGROUND

[0002] Intravascular thrombus is a relatively common clinical disease. A large volume of thrombus is difficult to be absorbed by itself, and often causes peripheral vascular occlusion, and even serious risk diseases such as myocardial infarction, ischemic stroke and pulmonary embolism, which seriously endanger human life and health. Traditional surgical thrombectomy has obvious defects, and causes great damage to patients. Relatively advanced drug thrombolysis and balloon angioplasty have a long drug thrombolysis time and general effect, and often cause complications such as nerve damage and tissue hemorrhage due to the use of drugs.

[0003] Studies have shown that, on the basis of catheter thrombolysis, the application of ultrasound can enhance the thrombolytic effect of drugs. Ultrasound produces cavitation effect, enhances the interaction between drugs and thrombus, and accelerates the dissolution of thrombus. However, in the process of ultrasonic thrombolysis, the ultrasonic transducer will heat up, which will cause damage to the device and reduce the efficiency if the heat is not removed in time. In general applications, it is easy to think of using flowing condensed water to remove heat in the case of ultrasonic transducer heating. In the application of interventional catheters, the general method is to pass physiological saline through the ultrasonic transducer catheter. The physiological saline is flowed through the ultrasonic transducer at a flow rate that can be tolerated by the human body, and then flowed into the human body blood vessels, so as to remove the heat of the transducer and cool the transducer. However, the method of flowing physiological saline through the transducer and into the human body blood vessels is restricted by the conditions of the human body. If the flow rate is too large, the human body cannot withstand it, and therefore the heat dissipation effect is general. SUMMARY

[0004] The purpose of the present application is to solve the problems in the prior art, and provide a multi-lumen tube capable of cooling an ultrasonic thrombolytic catheter transducer with circulating liquid.

[0005] To achieve the above-mentioned purpose, the technical scheme adopted by the present application is as follows:

[0006] A multi-lumen tube capable of cooling an ultrasonic thrombolytic catheter transducer with circulating liquid, comprising a main pipe, a main lumen in the center of the main pipe, and one or more than one drug liquid lumen and one or more than one physiological saline backwater lumen on the pipe wall of the main pipe;

[0007] The main lumen is used for passing an ultrasonic transducer guide wire, the distal end of the main lumen is circular, and the diameter is equal to the diameter of the distal end of the guide wire to avoid physiological saline flowing into the human body blood vessels, and the cross-sectional area of other positions of the main lumen is greater than the cross-sectional area of the guide wire;

[0008] The outer wall of the main pipe near the distal end is provided with more than one drug liquid outlet hole, and the inner wall of the main pipe near the distal end is provided with more than one physiological saline circulation hole;

[0009] The drug liquid cavity is not communicated with the main cavity and the physiological saline backwater cavity, the drug liquid cavity is communicated with the drug liquid outlet hole, and the drug liquid cavity extends to the proximal end of the main pipe;

[0010] The physiological saline backwater cavity is communicated with the main cavity through the physiological saline circulation hole, and the physiological saline backwater cavity extends to the proximal end of the main pipe.

[0011] As a preferred technical solution:

[0012] The multi-cavity pipe for cooling the transducer of the ultrasonic thrombolytic catheter by circulating liquid as described above comprises a cylindrical pipe section, and the proximal end of the main pipe is one end of the cylindrical pipe section.

[0013] The multi-cavity pipe for cooling the transducer of the ultrasonic thrombolytic catheter by circulating liquid as described above further comprises a connecting piece.

[0014] The connecting piece comprises an outer pipe, an inner pipe, a partition piece, a blocking piece, a physiological saline discharge pipe and a drug liquid injection pipe.

[0015] The distal end of the outer pipe is fixedly sleeved on the cylindrical pipe section, and the inner diameter of the outer pipe at other positions is greater than the outer diameter of the cylindrical pipe section.

[0016] The inner pipe is a cylindrical pipe with an inner diameter greater than the diameter of the guide wire, is located in the outer pipe, and the distal end of the inner pipe is attached to the proximal end of the main pipe.

[0017] The partition piece is an annular structure and is sleeved on the inner pipe; the outer pipe, the partition piece, the inner pipe and the main pipe jointly form a drug liquid storage cavity, and the drug liquid storage cavity is communicated with all the drug liquid cavities.

[0018] The blocking piece is an annular structure and is located at the proximal end of the outer pipe; the blocking piece, the inner pipe, the partition piece and the outer pipe jointly form a physiological saline storage cavity.

[0019] The physiological saline discharge pipe and the drug liquid injection pipe are located outside the outer pipe, the physiological saline discharge pipe is communicated with the physiological saline storage cavity, and the drug liquid injection pipe is communicated with the drug liquid storage cavity.

[0020] The partition piece is provided with a physiological saline through hole, the physiological saline through hole extends to the distal end of the inner pipe along the axial direction of the inner pipe to form a physiological saline backwater passage, the number of the physiological saline backwater passage is the same as that of the physiological saline backwater cavity, and the physiological saline backwater passage is connected with the physiological saline backwater cavity one by one; the physiological saline backwater passage is not in contact with the drug liquid injection pipe.

[0021] A multi-cavity tube for cooling an ultrasonic thrombolytic catheter transducer with circulating liquid as described above, the outer tube is connected by a connecting cone outer tube and a connecting cylinder outer tube which are coaxial and have the same wall thickness, the large end of the connecting cone outer tube is connected with the connecting cylinder outer tube, the inner diameter of the large end of the connecting cone outer tube is the same as the inner diameter of the connecting cylinder outer tube, and the inner diameter of the small end of the connecting cone outer tube is equal to the outer diameter of the cylindrical pipe section; the partition is located in the connecting cylinder outer tube.

[0022] A multi-cavity tube for cooling an ultrasonic thrombolytic catheter transducer with circulating liquid as described above, the main cavity is connected by a cone cavity and a cylindrical cavity which are coaxial, the large end of the cone cavity is connected with the cylindrical cavity, the diameter of the large end of the cone cavity is the same as the diameter of the cylindrical cavity, and the diameter of the small end of the cone cavity is equal to the diameter of the distal end of the guide wire; the cylindrical cavity is the central part of the cylindrical pipe section, the drug liquid cavity, the physiological saline backwater cavity, the drug liquid outlet hole and the physiological saline circulation hole are all arranged in the cylindrical pipe section, and the lengths of the drug liquid cavity and the physiological saline backwater cavity are the same as the cylindrical pipe section.

[0023] A multi-cavity tube for cooling an ultrasonic thrombolytic catheter transducer with circulating liquid as described above, the cross sections of the drug liquid cavity and the physiological saline backwater cavity are all fan-shaped and have the same size, the fan shape includes a long circular arc and a short circular arc, all the long circular arcs of the fan shapes are located on the same circle and are uniformly distributed, and all the short circular arcs of the fan shapes are located on the same circle and are uniformly distributed.

[0024] A multi-cavity tube for cooling an ultrasonic thrombolytic catheter transducer with circulating liquid as described above, the number of the physiological saline backwater cavities is two and they are symmetrically distributed, the number of the drug liquid cavities is four, and the cross-sectional shape and size of the physiological saline backwater passage are the same as those of the physiological saline backwater cavity.

[0025] Advantages

[0026] The multi-cavity tube for cooling an ultrasonic thrombolytic catheter transducer with circulating liquid can avoid the physiological saline flowing into the human body blood vessels, does not need to consider the tolerance of the human body, can maximize the heat dissipation of the ultrasonic transducer, thereby maximizing the performance of the ultrasonic transducer, improving the thrombolytic efficiency, reducing the thrombolytic time, and at the same time, in the thrombolytic process, no liquid enters the human body blood vessels, reducing the stimulation to the already diseased blood vessels, and improving the safety of the use of the instrument. BRIEF DESCRIPTION OF DRAWINGS

[0027] Figure 1 It is a schematic diagram of the overall appearance of the application;

[0028] Figure 2 It is Figure 1 It is a schematic diagram of the cross-sectional structure of A-A direction in the figure;

[0029] Figure 3 It is Figure 1A cross-sectional structure diagram of the middle B-B direction;

[0030] Figure 4 For Figure 1 A cross-sectional structure diagram of the middle C-C direction;

[0031] Figure 5 For Figure 1 A cross-sectional structure diagram of the middle D-D direction;

[0032] Figure 6 For Figure 1 A cross-sectional structure diagram of the middle E-E direction;

[0033] Figure 7 A three-dimensional structure diagram of the cylindrical pipe of the present application;

[0034] Figure 8 A cross-sectional structure diagram of the main pipe along the radial direction of the cylindrical pipe of the present application;

[0035] Figure 9 A flow direction diagram of the drug solution in the main pipe;

[0036] Figure 10 A flow direction diagram of the physiological saline in the present application;

[0037] Figure 11 A three-dimensional structure diagram of the distal end of the connecting piece of the present application (the obturator is omitted for the convenience of understanding);

[0038] Figure 12 A three-dimensional structure diagram of the proximal end of the connecting piece of the present application (the obturator is omitted for the convenience of understanding);

[0039] Wherein, 1-wire, 2-circular cone cavity, 3-cylindrical cavity, 4-drug solution outflow hole, 5-physiological saline circulation hole, 6-drug solution cavity, 7-physiological saline backwater cavity, 8-inner tube, 9-septum, 10-physiological saline discharge pipe, 11-drug solution injection pipe, 12-connecting piece circular cone outer pipe, 13-connecting piece cylindrical outer pipe, 14-physiological saline through hole, 15-main pipe, 16-obturator, 17-drug solution storage cavity, 18-physiological saline storage cavity. DETAILED DESCRIPTION

[0040] The present application will be further described below in conjunction with specific embodiments. It should be understood that these embodiments are only used to illustrate the present application and not used to limit the scope of the present application. In addition, it should be understood that after reading the content taught by the present application, those skilled in the art can make various modifications or changes to the present application, and these equivalent forms also fall within the scope defined by the appended claims of the present application.

[0041] A multi-cavity pipe for cooling the transducer of an ultrasonic thrombolytic catheter with circulating liquid, comprising Figures 1-12As shown, it includes the main pipe 15 and connectors;

[0042] like Figure 8 As shown, the central part of the main conduit 15 is the main cavity through which the guide wire 1 of the ultrasonic transducer passes. The main cavity is formed by connecting a coaxial frustum cavity 2 and a cylindrical cavity 3. The large end of the frustum cavity 2 is connected to the cylindrical cavity 3, and the diameter of the large end of the frustum cavity 2 is the same as the diameter of the cylindrical cavity 3. The diameter of the small end of the frustum cavity 2 is equal to the diameter of the distal end of the guide wire 1. The cylindrical cavity 3 is the central part of a cylindrical tube, and the frustum cavity 2 is the central part of a frustum tube. The main conduit 15 is formed by connecting the aforementioned cylindrical tube and the aforementioned frustum tube. The distal end of the main cavity is the small end of the frustum cavity 2.

[0043] like Figure 7 As shown, one or more medicine outlet holes 4 are provided on the outer wall near the distal end of the cylindrical pipe, and one or more saline circulation holes 5 are provided on the inner wall near the distal end of the cylindrical pipe.

[0044] like Figure 4 , Figure 5 As shown, the cylindrical pipe has four drug solution channels 6 and two symmetrically distributed saline return channels 7 inside its wall; the lengths of the drug solution channels 6 and the saline return channels 7 are the same as those of the cylindrical pipe, and the cross-sections of the drug solution channels 6 and the saline return channels 7 are all fan-shaped and have the same size. The fan shape includes long arcs and short arcs. The long arcs of all fan shapes are located on the same circle and are evenly distributed, and the short arcs of all fan shapes are located on the same circle and are evenly distributed.

[0045] The drug solution channel 6 is not connected to the main channel or the saline return channel 7. The drug solution channel 6 is connected to the drug solution outlet 4. The saline return channel 7 is connected to the main channel through the saline circulation hole 5.

[0046] like Figures 1-3 , Figures 10-12 As shown, the connector includes an outer tube, an inner tube 8, a diaphragm 9, a sealing plate 16, a saline discharge tube 10, and a drug injection tube 11;

[0047] The outer tube is formed by connecting a coaxial frustum outer tube 12 and a cylindrical outer tube 13 with the same wall thickness. The large end of the frustum outer tube 12 is connected to the cylindrical outer tube 13. The inner diameter of the large end of the frustum outer tube 12 is the same as the inner diameter of the cylindrical outer tube 13. The inner diameter of the small end of the frustum outer tube 12 is equal to the outer diameter of the cylindrical tube. The far end of the outer tube is fixedly sleeved on the near end of the main tube 15.

[0048] The inner tube 8 is a cylindrical tube with an inner diameter larger than that of the guide wire 1; the distal end of the inner tube 8 is attached to the proximal end of the main pipe 15.

[0049] The spacer 9 is annular structure, and the spacer 9 is provided with physiological saline through holes 14, the physiological saline through holes 14 extend to the distal end of the inner tube 8 along the axial direction of the inner tube 8 to form physiological saline backwater channels, the physiological saline backwater channels are same in number with the physiological saline backwater channels 7, and are connected one by one in one-to-one correspondence;

[0050] The blocking piece 16 is annular structure;

[0051] The inner tube 8 is located in the outer tube; the physiological saline discharge pipe 10 and the liquid medicine injection pipe 11 are located outside the outer tube, the liquid medicine injection pipe 11 does not contact the physiological saline backwater channels; the spacer 9 is located in the connecting piece cylindrical outer tube 13 and is sleeved on the inner tube 8, the outer tube, the spacer 9, the inner tube 8 and the main pipeline 15 jointly enclose the liquid medicine storage cavity 17, the liquid medicine storage cavity 17 is communicated with the liquid medicine injection pipe 11 and all the liquid medicine channels 6; the blocking piece 16 is located at the proximal end of the outer tube, and the blocking piece 16, the inner tube 8, the spacer 9 and the outer tube jointly enclose the physiological saline storage cavity 18, and the physiological saline storage cavity 18 is communicated with the physiological saline discharge pipe 10 and all the physiological saline backwater channels.

[0052] As shown in the figure, Figure 10 When the multi-cavity tube of the application is used, the physiological saline is sent into the main channel in the central part of the main pipeline 15 together with the guide wire through the inner tube 8, and because the small end diameter of the circular cone channel 2 is equal to the diameter of the distal end of the guide wire 1, the physiological saline will not flow out from the small end of the circular cone channel 2, but enter the physiological saline backwater channel 7 through the physiological saline circulation hole 5, then enter the physiological saline backwater channel 7 connected with the physiological saline backwater channel 7, and then successively pass through the physiological saline storage cavity 18 and the physiological saline discharge pipe 10 to be discharged; the liquid medicine enters the liquid medicine storage cavity 17 through the liquid medicine injection pipe 11, then enters the liquid medicine channel 6 communicated with the liquid medicine storage cavity 17, and finally flows out through the liquid medicine outflow hole 4.

Claims

1. A multi-lumen tube for use with circulating fluid to cool the transducer of an ultrasonic thrombolysis catheter, characterized in that, It includes a main pipeline, the central part of which is the main cavity, and the pipe wall of the main pipeline has one or more drug solution cavities and one or more saline return water cavities. The main cavity is used for the ultrasonic transducer guidewire to pass through. The distal end of the main cavity is circular and its diameter is equal to the diameter of the distal end of the guidewire. The cross-sectional area of ​​other parts of the main cavity is larger than the cross-sectional area of ​​the guidewire. One or more medicine outlet holes are provided on the outer wall near the distal end of the main pipe, and one or more saline circulation holes are provided on the inner wall near the distal end of the main pipe. The drug solution channels are not connected to the main channel or the saline return channel. The drug solution channels are connected to the drug solution outflow hole and extend to the proximal end of the main channel. The saline return channel is connected to the main channel through the saline circulation hole, and the saline return channel extends to the proximal end of the main channel. The main pipeline consists of a cylindrical pipe section, with the proximal end of the main pipeline being one end of the cylindrical pipe section. The multi-lumen tube of the ultrasonic thrombolytic catheter transducer, which can be cooled by circulating fluid, also includes connectors. The connectors include an outer tube, an inner tube, a septum, a sealing plate, a saline discharge tube, and a drug injection tube; The distal end of the outer tube is fixedly sleeved on the cylindrical pipe section, and the inner diameter of the outer tube at other locations is larger than the outer diameter of the cylindrical pipe section. The inner tube is a cylindrical tube with an inner diameter larger than that of the guide wire; the inner tube is located inside the outer tube; the distal end of the inner tube is in contact with the proximal end of the main pipe. The partition is a ring structure that fits onto the inner tube; the outer tube, partition, inner tube, and main pipe together form a medicine storage cavity, which is connected to all medicine channels. The occlusion piece has a ring structure and is located at the proximal end of the outer tube; the occlusion piece, the inner tube, the septum, and the outer tube together form a saline storage cavity; The saline drain tube and the drug injection tube are located outside the outer tube. The saline drain tube is connected to the saline storage chamber, and the drug injection tube is connected to the drug storage chamber. The septum is provided with saline through holes, which extend along the axial direction of the inner tube to the distal end of the inner tube to form saline return channels. The number of saline return channels and saline return cavities are the same and they are connected one-to-one. The saline return channels do not contact the drug injection tube.

2. The multi-lumen tube of an ultrasonic thrombolytic catheter transducer that can be cooled with circulating fluid according to claim 1, characterized in that, The outer tube is formed by connecting a coaxial frustum outer tube and a cylindrical outer tube with the same wall thickness. The large end of the frustum outer tube is connected to the cylindrical outer tube. The inner diameter of the large end of the frustum outer tube is the same as the inner diameter of the cylindrical outer tube. The inner diameter of the small end of the frustum outer tube is equal to the outer diameter of the cylindrical pipe section. The partition is located inside the cylindrical outer tube.

3. A multi-lumen tube for use with a circulating fluid-cooled ultrasonic thrombolysis catheter transducer according to claim 1, characterized in that, The main channel is formed by connecting a coaxial frustum channel and a cylindrical channel. The large end of the frustum channel is connected to the cylindrical channel, and the diameter of the large end of the frustum channel is the same as the diameter of the cylindrical channel. The diameter of the small end of the frustum channel is equal to the diameter of the distal end of the guidewire. The cylindrical channel is the central part of the cylindrical pipe section. The drug solution channel, the saline return channel, the drug solution outlet, and the saline circulation hole are all located in the cylindrical pipe section. The lengths of the drug solution channel and the saline return channel are the same as those of the cylindrical pipe section.

4. A multi-lumen tube for an ultrasonic thrombolysis catheter transducer that can be cooled with circulating fluid according to claim 3, characterized in that, The cross-sections of the drug solution cavity and the saline return cavity are both fan-shaped and of the same size. The fan shape includes long arcs and short arcs. The long arcs of all fan shapes are located on the same circle and are evenly distributed. The short arcs of all fan shapes are located on the same circle and are evenly distributed.

5. A multi-lumen tube for an ultrasonic thrombolysis catheter transducer that can be cooled with circulating fluid according to claim 4, characterized in that, There are two saline return channels, which are symmetrically distributed; there are four drug solution channels; the cross-sectional shape and size of the saline return channel are the same as those of the saline return channel.

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