Anti-embolism filter and filter membrane

Abstract

The present invention provides an anti-embolism filter and filter membrane. The anti-embolism filter comprises a support; a filter membrane comprising an outer membrane and an inner membrane, the outer membrane being connected to the support; the inner membrane being connected to the outer membrane, and a containment space being formed between the inner and outer membranes. The present invention utilizes the filter membrane to block embolic particles from entering the brain through the bloodstream. The inner and outer membranes then encapsulate the embolic particles within the containment space formed by the membranes, recovering them, and removing them from the body.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to an anti-embolism filter and a filter membrane. Background Art

[0002] Embolic particles from thrombi, calcifications, and atheromatous plaques generated during cardiac interventional procedures can be dislodged through surgery or catheterization and enter the bloodstream, where they can embolize via cerebral vessels in the brain or other vital organs downstream. Cerebral embolism can lead to neuropsychological deficits, stroke, and even death. Therefore, blocking the bloodstream from embolic particles entering the brain is essential during surgery.

[0003] Current anti-embolism filters have the ability to block embolic particles, but the effect of recovering embolic particles is not ideal. Summary of the Invention

[0004] The technical problem to be solved by the present application is to provide an anti-embolism filter that can block embolic particles from entering the brain through the bloodstream and can also recover the embolic particles.

[0005] The present application provides an anti-embolism filter, comprising: a bracket; a filter membrane, wherein the filter membrane comprises an outer membrane and an inner membrane, the outer membrane is connected to the bracket, the inner membrane is connected to the outer membrane, and a receiving space is formed between the inner membrane and the outer membrane.

[0006] The present application blocks embolic particles from entering the brain through the bloodstream through a filter membrane, and wraps the embolic particles in the containment space formed by the inner and outer membranes and recovers them out of the body. Even tiny embolic particles can be completely taken out, and the recovery is more thorough, reducing the risk of embolic particles entering the brain.

[0007] In some embodiments, the inner membrane is connected to the outer membrane at the downstream end in the blood flow direction; a connecting component is connected between the inner membrane and the outer membrane or the stent at the upstream end in the blood flow direction.

[0008] In the present application, the connecting component can prevent the inner membrane from shifting under the impact of blood flow, thereby keeping the inner membrane in the outer membrane, and further ensuring that a receiving space for receiving embolic particles is always formed between the inner membrane and the outer membrane.

[0009] In some embodiments, the inner membrane is formed with a small port and a large port, wherein the small port is located at the upstream end of the inner membrane in the blood flow direction and is connected to the connecting component, and the large port is located at the downstream end of the inner membrane in the blood flow direction and is connected to the outer membrane.

[0010] In some embodiments, the small port of the inner membrane is located in the middle of the length direction of the outer membrane; or, the small port of the inner membrane is located close to the middle of the length direction of the outer membrane.

[0011] In this application, the inner membrane extends from the downstream end to the upstream end in the direction of blood flow, and the small port faces the direction of blood flow for inserting a catheter. When no catheter is inserted, the small port closes under the impact of blood flow to prevent embolic particles in the blood flow from passing through.

[0012] In some embodiments, the inner membrane includes a connected conical segment and a cylindrical segment, the conical segment is located downstream of the cylindrical segment in the direction of blood flow, the small port is arranged in the cylindrical segment, and the large port is arranged in the conical segment.

[0013] In this application, the cylindrical section is a straight structure that is flattened and closed by the impact of blood flow when no catheter is inserted. This prevents embolic particles such as thrombi in the blood flow from flowing out of the small port. When passing through the catheter, the cylindrical section has an overlapping portion with the catheter, which can better fit the catheter and prevent embolic particles such as thrombi from escaping through the gap between the catheter and the cylindrical section. The diameter of the cylindrical section can be adapted to the diameter of the catheter insertion portion, ensuring that the catheter can pass through the cylindrical section while also preventing embolic particles from escaping.

[0014] In some embodiments, the conical section is coaxial with the cylindrical section. The conical section and the cylindrical section are centrally symmetrical structures, and no circumferential positioning needs to be considered when placing them. The small port can be located in the center at any angle, which facilitates placement.

[0015] In some embodiments, the connecting component includes a connecting belt and / or a support rod.

[0016] In some embodiments, the connecting component includes a connecting wire, and the connecting wire includes a first connecting segment, and the first connecting segment is embedded in the inner membrane or attached to the surface of the inner membrane.

[0017] In some embodiments, the connecting line includes a second connecting segment connected to the first connecting segment, and the second connecting segment is embedded in the outer membrane or attached to the surface of the inner membrane.

[0018] In some embodiments, the connecting line includes a third connecting segment whose two ends are respectively connected to the first connecting segment and the second connecting segment, and the third connecting segment is located between the small port of the inner membrane and the upstream end of the outer membrane in the blood flow direction.

[0019] In some embodiments, a plurality of the connecting components are provided, and the plurality of connecting components are distributed along the circumference of the inner membrane.

[0020] In some embodiments, the stent is formed with a cavity, the filter membrane is located in the cavity, and the outer membrane is attached to the inner surface of the stent.

[0021] The present application provides a filter membrane for an anti-embolism filter, wherein the filter membrane is the filter membrane as described in any of the above embodiments.

[0022] The present application blocks embolic particles from entering the brain through the bloodstream through a filter membrane, and wraps the embolic particles in the containment space formed by the inner membrane and the outer membrane to recover them and take them out of the body.

[0023] The present application provides an anti-embolism filter, comprising: a stent capable of forming a cavity; a filter membrane, arranged in the cavity of the stent, the filter membrane comprising an outer membrane and an inner membrane, the outer membrane being attached to the inner surface of the stent, a receiving space being formed between the outer membrane and the inner membrane, the inner membrane comprising a connected conical section and a cylindrical section, the conical section being located downstream of the cylindrical section in the direction of blood flow, the downstream end of the conical section in the direction of blood flow being connected to the downstream end of the outer membrane in the direction of blood flow, and a connecting component being connected between the upstream end of the cylindrical section in the direction of blood flow and the upstream end of the outer membrane in the direction of blood flow. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following is a brief introduction to the drawings required for use in the embodiments of the present application. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0025] Figure 1 A schematic structural diagram of an anti-embolism filter provided in an embodiment of the present application in an implanted state;

[0026] Figure 2 This is a schematic structural diagram of an anti-embolism filter in a delivery state provided by an embodiment of the present application;

[0027] Figure 3 A cross-sectional view of the filter membrane of the anti-embolism filter provided in an embodiment of the present application;

[0028] Figure 4 A cross-sectional view of an anti-embolism filter provided in another embodiment of the present application;

[0029] Figure 5 A cross-sectional view of a filter membrane of an anti-embolism filter provided in yet another embodiment of the present application;

[0030] Figure 6 This is a schematic diagram of the connecting line structure provided in an embodiment of the present application. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present application will be described below in conjunction with the drawings in the embodiments of the present application.

[0032] It should be noted that similar reference numerals and letters represent similar items in the following drawings. Therefore, once an item is defined in one drawing, it does not need to be further defined or explained in subsequent drawings. At the same time, in the description of this application, the terms "first", "second", etc. are only used to distinguish the description and should not be understood as indicating or implying relative importance.

[0033] Please refer to Figure 1 and Figure 2 , Figure 1 A schematic structural diagram of an anti-embolism filter provided in an embodiment of the present application. Figure 2 This is a schematic structural diagram of an anti-embolism filter in a delivery state provided in an embodiment of the present application.

[0034] An embodiment of the present application provides an anti-embolism filter, comprising: a bracket 10; a filter membrane 20, the filter membrane comprising an outer membrane 21 and an inner membrane 22, the outer membrane 21 being connected to the bracket 10, the inner membrane 22 being connected to the outer membrane 21, and a receiving space 23 being formed between the inner membrane 22 and the outer membrane 21.

[0035] The anti-embolism filter has a radially contractible delivery state ( Figure 2 shown) and the implanted state in radial expansion ( Figure 1 As shown in FIG, when the anti-embolism filter is implanted, the stent 10 and the filter membrane 20 are radially expanded, forming a radial support between the stent 10 and the blood vessel wall. The blood flows through the filter membrane 20 and is filtered, blocking embolic particles such as thrombus, calcification and atheromatous plaques during the operation and accommodating them in the accommodation space 23 formed between the inner membrane 22 and the outer membrane 21. When the operation is completed, the anti-embolism filter is changed from the implanted state to the transport state through the corresponding recovery device. At this time, the stent 10 and the filter membrane 20 are radially contracted, wrapping the embolic particles in the accommodation space 23 and finally taking them out of the body.

[0036] The anti-embolism filter of the present embodiment blocks embolic particles from entering the brain through the bloodstream via the filter membrane 20. The endo- and exo-membranes 22 and 21 enclose the embolic particles within the containment space formed by the membranes, allowing them to be recovered and removed from the body. Because the filter pores of the filter membrane can be smaller than those formed by the stent itself in the prior art, and because the filter membrane of the present invention forms a containment space, even relatively small embolic particles can be recovered and removed, resulting in more thorough recovery and reducing the risk of embolic particles entering the brain.

[0037] In some embodiments, reference Figure 3 The inner membrane 22 is connected to the outer membrane 21 at the downstream end 221 in the blood flow direction A; a connecting component 30 is connected between the inner membrane 22 and the outer membrane 21 or the stent 10 at the upstream end 222 in the blood flow direction A. For ease of display, the filter membrane structure, Figure 3The stent is not shown in the figure. In actual use, the outer membrane 21 is attached to the stent 10.

[0038] The connecting component 30 can prevent the inner membrane 22 from shifting under the impact of blood flow, thereby retaining the inner membrane 22 in the outer membrane 21, so that a receiving space 23 for receiving embolic particles is always formed between the inner membrane 22 and the outer membrane 21.

[0039] In some examples, the connecting member 30 includes a connecting belt and / or a support rod. The connecting member 30 can be a flexible connecting belt or a rigid support rod. The flexible connecting belt can pull and / or pull the endothelium 22 under the impact of blood flow. The rigid support rod can provide support for the endothelium 22 under the impact of blood flow.

[0040] Optionally, refer to Figure 4 The connecting parts 30 may be provided in plurality, and the plurality of connecting parts 20 are distributed along the circumference C of the inner membrane 22. When impacted by blood flow, multiple positions of the inner membrane 22 form pulling and / or traction and / or support to ensure that the inner membrane 22 always remains in the outer membrane 21.

[0041] In some embodiments, reference Figure 2 The inner membrane 22 is formed with a small port 223 and a large port 224, wherein the small port 223 is located at the upstream end 222 of the inner membrane 22 in the blood flow direction, and the small port 223 is connected to the connecting component 30, and the large port 224 is located at the downstream end 221 of the inner membrane 22 in the blood flow direction and is connected to the outer membrane 21.

[0042] The inner membrane 22 extends from the downstream end 221 in the blood flow direction A to the upstream end 222, and the small port 223 faces the blood flow direction A for inserting a catheter. When no catheter is inserted, the small port 223 closes under the impact of blood flow to prevent embolic particles from passing through.

[0043] For example, the large port 224 of the inner membrane 22 can be connected to the downstream end of the outer membrane 21 in the blood flow direction A by gluing or suturing. The inner membrane 22 extends from the large port 224 to the small port 223 along the reverse blood flow direction (the direction opposite to the blood flow direction A), and the diameter of the inner membrane 22 decreases from the large port 224 to the small port 223.

[0044] In some embodiments, the small port 223 of the inner membrane 22 is located in the middle of the length direction of the outer membrane 21 ; or, the small port 223 of the inner membrane 22 is located close to the middle of the length direction of the outer membrane 21 .

[0045] The small port 223 of the inner membrane 22 is at or near the middle position in the length direction of the outer membrane 21. On the one hand, it ensures that the inner membrane 22 is in the inner cavity of the outer membrane 21. On the other hand, it ensures that the inlet space at the upstream end of the outer membrane 21 is not affected. The embolic particles follow the blood flow and smoothly enter the inner cavity of the outer membrane 21. They are then blocked by the inner membrane 22 and then contained in the containing space formed between the inner membrane 22 and the outer membrane 21.

[0046] In some embodiments, reference Figure 3 The inner membrane 22 includes a connected conical section 225 and a cylindrical section 226. In the blood flow direction A, the conical section 225 is located downstream of the cylindrical section 226. The small port 223 is set in the cylindrical section 226, and the large port 224 is set in the conical section 225.

[0047] Cylindrical section 226 is a straight structure that, when not inserted into the catheter, is flattened and closed by the impact of blood flow, preventing thrombi and other embolic particles in the bloodstream from escaping from small port 223. When passing through the catheter, cylindrical section 226 overlaps with the catheter for a certain portion, providing a better fit and preventing thrombi and other embolic particles from escaping through the gap between the catheter and the cylindrical section. The diameter of cylindrical section 226 is compatible with the diameter of the catheter insertion portion, ensuring that the catheter can pass through cylindrical section 226 while also preventing embolic particles from escaping.

[0048] In some embodiments, the conical section 225 is coaxial with the cylindrical section 226. The conical section 225 and the cylindrical section 226 are centrally symmetrical structures, and no circumferential positioning is required when placing them. The small port 223 can be located in the center at any angle, which facilitates placement.

[0049] In other embodiments, the conical section 225 and the cylindrical section 226 may be non-coaxial, and the conical section 225 and the cylindrical section 226 may be eccentric. In this case, the small port 223 can be positioned upwards for easy positioning during placement. This facilitates the passage of subsequent surgical instruments through the small port 223 after placement, and the eccentric structure further facilitates the passage of subsequent surgical instruments.

[0050] In some embodiments, reference Figure 5 and Figure 6 The connecting component 30 may include a connecting line, the connecting line includes a first connecting segment 31, and the first connecting segment 31 is buried in the inner membrane 22.

[0051] The connecting line further includes a second connecting section 32 connected to the first connecting section 31 , and the second connecting section 32 is buried in the outer membrane 21 .

[0052] The connecting line further includes a third connecting segment 33 connected to the first connecting segment 31 and the second connecting segment 32 at both ends. The third connecting segment 33 is located between the small port 223 of the inner membrane 22 and the upstream end 211 of the outer membrane 21 in the blood flow direction.

[0053] Optionally, the first connecting segment 31 , the second connecting segment 32 and the third connecting segment 33 may form a closed structure. The connection may be by knotting, bonding or indirectly connecting the closed structure through a polymer filter membrane at the end 223 of the cylindrical segment 226 .

[0054] The connecting line can be directly fused and embedded into the polymer filter membrane, or fixed to the filter membrane surface by bonding or suturing. The connecting line is attached to the surface of the polymer membrane and can be located outside the filter membrane 22 or inside the filter membrane 20, or partially outside and partially inside the filter membrane 20. A preferred structure is one in which the first connecting segment 31 and the second connecting segment 32 are embedded in the middle of the filter membrane, with the polymer filter membrane encapsulating the first and second connecting segments 31, 32.

[0055] The connecting wire can be a slender structure, comprising a single or multiple twisted strands or ropes with good flexibility. Alternatively, it can be a ribbon-like structure, characterized by its flexibility and bendability. Preferably, its maximum cross-sectional dimension is between 0.05 and 0.2 mm. Multiple slender structures can be arranged along the circumference, with one or more strands. Multiple strands can be evenly or unevenly distributed.

[0056] In some embodiments, the stent 10 is formed with a cavity 11, and the filter membrane 20 is located in the cavity 11, wherein the outer membrane 21 is attached to the inner surface of the stent 10. When the stent 10 is deployed, the outer membrane 21 may be cylindrical.

[0057] The embodiment of the present application further provides a filter membrane for an anti-embolism filter, which is the filter membrane 20 mentioned in the above embodiment.

[0058] The present application also provides an anti-embolism filter, referring to Figure 1-6 , including: a stent 10 capable of forming a cavity 11 in an expanded state; a filter membrane 20 is arranged in the cavity 11 of the stent 10, the filter membrane 20 includes an outer membrane 21 and an inner membrane 22, the outer membrane 21 is attached to the inner surface of the stent 10, and a receiving space 23 is formed between the outer membrane 21 and the inner membrane 20, the inner membrane 22 includes a connected conical section 225 and a cylindrical section 226, in the blood flow direction A, the conical section 225 is located downstream of the cylindrical section 226, the downstream end 221 of the conical section 225 in the blood flow direction C is connected to the downstream end 211 of the outer membrane 21 in the blood flow direction, and a connecting component is connected between the upstream end 223 of the cylindrical section 226 in the blood flow direction A and the upstream end 212 of the outer membrane 21 in the blood flow direction A.

[0059] Filter holes can be formed on the inner membrane 22 and / or the outer membrane 21. The filter membrane 20 can be made of a polymer film, and the inner membrane 22 has a conical structure, and the closing end (small port 223) of the conical structure is located in the middle of the two ports of the outer membrane 21. The outer membrane can be cylindrical, and the inner membrane has a conical structure, and both the outer membrane and the inner membrane are polymer film structures. In order to maintain the conical structure of the inner membrane and insert it inverted into the cylindrical structure of the outer membrane, a connecting component 30 is provided at the port (small port 223) at one end of the inner membrane, and the connecting component 30 is connected to the opening of the port (upstream end 212) of the outer membrane. The length of the connecting component 30 is set to ensure that the small port of the inner membrane 22 is located inside the outer membrane 21.

[0060] The anti-embolism filter is equipped with a filter membrane that can block embolic particles such as thrombi and detached plaques, and capture these embolic particles in the containment space between the inner and outer membranes. During the recovery process, all captured embolic particles such as thrombi and detached plaques can be taken out of the body, ensuring the protection of distal blood vessels throughout the operation, preventing the occurrence of distal embolic events to the greatest extent, and achieving protection of distal arterial vessels throughout the body.

[0061] The foregoing is merely an embodiment of the present application and is not intended to limit the scope of protection of the present application. Various modifications and variations are possible for those skilled in the art. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application shall be included within the scope of protection of the present application. It should be noted that similar reference numerals and letters represent similar items in the following figures. Therefore, once an item is defined in one figure, it does not need to be further defined or explained in subsequent figures.

[0062] The above description is merely a specific embodiment of the present application, but the scope of protection of the present application is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present application should be included in the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of the rights described above.

[0063] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply the existence of any such actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or device comprising the element.

Claims

1. An anti-embolism filter, characterized in that: include: Bracket; a filter membrane, the filter membrane comprising an outer membrane and an inner membrane, the outer membrane being connected to the support, the inner membrane being connected to the outer membrane, and a receiving space being formed between the inner membrane and the outer membrane; The inner membrane includes a connected conical segment and a cylindrical segment. In the direction of blood flow, the conical segment is located downstream of the cylindrical segment. The inner membrane is formed with a small port and a large port. The small port is arranged in the cylindrical segment, and the large port is arranged in the conical segment. The small port is used for inserting a catheter, wherein when the catheter is not inserted, the small port can be closed under the impact of blood flow.

2. The anti-embolism filter according to claim 1, characterized in that The inner membrane is connected to the outer membrane at a downstream end in the blood flow direction; A connecting component is connected between the upstream end of the inner membrane in the blood flow direction and the outer membrane or the stent.

3. The anti-embolism filter according to claim 2, characterized in that The small port is located at the upstream end of the inner membrane in the blood flow direction and is connected to the connecting component. The large port is located at the downstream end of the inner membrane in the blood flow direction and is connected to the outer membrane.

4. The anti-embolism filter according to claim 3, characterized in that The small port of the inner membrane is located in the middle of the outer membrane in the length direction; or, The small port of the inner membrane is located close to the middle position in the length direction of the outer membrane.

5. The anti-embolism filter according to claim 2, characterized in that The conical section is coaxial with the cylindrical section.

6. The anti-embolism filter according to any one of claims 2 to 5, characterized in that: The connecting components include connecting belts and / or supporting rods.

7. The anti-embolism filter according to any one of claims 2 to 5, characterized in that: The connecting component includes a connecting line, and the connecting line includes a first connecting segment. The first connecting segment is embedded in the inner membrane or attached to the surface of the inner membrane.

8. The anti-embolism filter according to claim 7, characterized in that The connecting line includes a second connecting segment connected to the first connecting segment, and the second connecting segment is embedded in the outer membrane or attached to the surface of the inner membrane.

9. The anti-embolism filter according to claim 8, characterized in that The connecting line includes a third connecting segment with two ends respectively connected to the first connecting segment and the second connecting segment. The third connecting segment is located between the small port of the inner membrane and the upstream end of the outer membrane in the blood flow direction.

10. The anti-embolism filter according to any one of claims 2 to 5, characterized in that: A plurality of connecting components are provided, and the plurality of connecting components are distributed along the circumference of the inner membrane.

11. The anti-embolism filter according to any one of claims 1 to 5, characterized in that: The support is formed with a cavity, and the filter membrane is located in the cavity, wherein the outer membrane is attached to the inner surface of the support.

12. An anti-embolism filter, characterized in that: include: a stent capable of forming a cavity; A filter membrane is arranged in the cavity of the support, and the filter membrane includes an outer membrane and an inner membrane. The outer membrane is attached to the inner surface of the support, and a receiving space is formed between the outer membrane and the inner membrane. The inner membrane includes a connected conical section and a cylindrical section. In the direction of blood flow, the conical section is located downstream of the cylindrical section, and the downstream end of the conical section in the direction of blood flow is connected to the downstream end of the outer membrane in the direction of blood flow. A connecting component is connected between the upstream end of the cylindrical section in the direction of blood flow and the upstream end of the outer membrane in the direction of blood flow.

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