A powder mixing pharmaceutical equipment for pharmaceutical engineering

Abstract

This invention discloses a powder mixing pharmaceutical device for pharmaceutical engineering, comprising a cylindrical drum, a fixed plate fixedly connected to the top of the drum, an openable cover hinged to the outer wall of the fixed plate, a motor fixedly connected to the top of the fixed plate, a connecting rod fixedly connected to the output end of the motor, and a mixing mechanism provided on the outer wall of the connecting rod. This relates to the field of pharmaceutical technology. By setting up the mixing mechanism, the bearing disc B rotates on the outer wall of the annular sleeve, causing the spring to deform. Simultaneously, the rotation of the threaded rod and the bearing disc B causes the threaded rod and the bearing disc B to rotate synchronously. Furthermore, the bristles on the outer wall of the stirring rod are agitated by the rotating threaded rod, causing the bristles to rebound due to their own elasticity, rapidly agitating the powder and improving the powder mixing efficiency. The rapid rebound of the bristles also disperses any clumps of powder adhering to the bristles, preventing adhesion from affecting the mixing effect.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical technology, specifically to a powder mixing pharmaceutical equipment for pharmaceutical engineering. Background Technology

[0002] The chemical pharmaceutical manufacturing sector consists of two parts: active pharmaceutical ingredient (API) production and pharmaceutical formulation production. APIs are the material basis for pharmaceutical production, but they must be processed into pharmaceutical formulations suitable for oral administration to become pharmaceuticals.

[0003] Referring to patent application CN114307739A, a powder mixing pharmaceutical device for pharmaceutical engineering is described, specifically a powder mixing pharmaceutical device for pharmaceutical engineering, relating to the pharmaceutical field. It includes a housing and support legs fixed to the bottom of the housing; the housing is fixedly connected to an inlet and an outlet; the housing is fixedly connected to a secondary dosing tank mechanism and a first support; the first support is fixedly connected to a first motor support; the first motor support is fixedly connected to a first motor; the output shaft of the first motor is fixedly connected to a first rotating shaft; the first rotating shaft is fixedly connected to a rotating rod mechanism; the rotating rod mechanism is rotatably connected to a mixing mechanism; the mixing mechanism is rotatably connected to a connecting rod mechanism; the connecting rod mechanism is fixedly connected to a slider mechanism; the slider mechanism is fixedly connected to a dial wheel discharge mechanism; and the dial wheel discharge mechanism is rotatably connected to a second support.

[0004] In current pharmaceutical engineering, when mixing powders, the powders are less fluid than liquids and have poor flowability. Therefore, it is easy for uneven mixing to occur between the top and bottom layers, as well as between the inner and outer layers. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a powder mixing pharmaceutical equipment for pharmaceutical engineering, thereby solving the aforementioned problems.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solution: a powder mixing pharmaceutical equipment for pharmaceutical engineering, comprising a cylindrical barrel, a first fixed plate fixedly connected to the top of the cylindrical barrel, an opening and closing cover hinged to the outer wall of the first fixed plate, a motor fixedly connected to the top of the first fixed plate, a connecting rod fixedly connected to the output end of the motor, and a mixing mechanism provided on the outer wall of the connecting rod;

[0007] The hybrid mechanism includes:

[0008] The connecting sleeve is a hollow cylindrical structure. The inner wall of the connecting sleeve is fixedly connected to the outer wall of the connecting rod. A fixing sleeve is fixedly connected to the outer wall of the connecting sleeve. A stirring rod is fixedly connected to the outer wall of the fixing sleeve. Brush bristles are fixedly connected to the outer wall of the stirring rod. The connecting sleeve is used to rotate synchronously with the connecting rod and drive the stirring rod to rotate.

[0009] An annular sleeve is provided, with a sliding rod fixedly connected to its outer wall. One end of the sliding rod is slidably connected to the inner wall of the cylindrical barrel. A rotating sleeve is rotatably connected to the outer wall of the stirring rod, and a lever is fixedly connected to the outer wall of the rotating sleeve.

[0010] Preferably, a bearing disk A is fixedly connected to the outer wall of the rotating sleeve, and a turntable is fixedly connected to the outer wall of the bearing disk A. The outer wall of the turntable is provided with a toothed groove A, and the inner wall of the annular sleeve is provided with a toothed groove B. The outer wall of the bearing disk A is rotatably connected to the outer wall of the annular sleeve, thereby allowing rotation.

[0011] Preferably, the inner wall of the tooth groove B meshes with the inner wall of the tooth groove A, the outer wall of the annular sleeve is rotatably connected to the bearing disk B, the outer wall of the bearing disk B is fixedly connected to the spring, one end of the spring is fixedly connected to the ring, the inner wall of the ring is fixedly connected to the outer wall of the stirring rod, and the stirring rod is provided with a flipping mechanism.

[0012] Preferably, the flipping mechanism includes a groove, which is formed inside the dial plate. The groove and the inner wall of the dial plate have a circular hole. A threaded rod is fixedly connected to the outer wall of the gear. One end of the threaded rod is fixedly connected to a second fixing plate. The inner wall of the second fixing plate is rotatably connected to the outer wall of the stirring rod, thereby allowing relative rotation.

[0013] Preferably, the outer wall of the threaded rod is threaded with an internal threaded sleeve, the outer wall of the internal threaded sleeve is fixedly connected to a limiting plate, the outer wall of the limiting plate is fixedly connected to a small spring, one end of the small spring is fixedly connected to the outer wall of the second fixing plate, and the outer wall of the second fixing plate is fixedly connected to a telescopic rod, one end of the telescopic rod is fixedly connected to the outer wall of the limiting plate, thereby fixing the limiting plate.

[0014] Preferably, the inner wall of the groove is an arc-shaped inclined surface, and the inner wall of the circular hole is a perfect circle, so that powder can pass through.

[0015] Preferably, the thread helix angle of the outer wall of the threaded rod is greater than 45 degrees, and the thread pitch of the outer wall of the threaded rod is large, thereby reducing the rotational friction.

[0016] Preferably, the bristles are made of rubber and are elastic, thus allowing them to deform.

[0017] This invention provides a powder mixing pharmaceutical device for pharmaceutical engineering. It has the following beneficial effects:

[0018] 1. This invention, through the setting of a mixing mechanism, when the gear is driven to rotate and move, the gear will synchronously drive the threaded rod and bearing disk B to rotate. The bearing disk B rotates on the outer wall of the annular sleeve, causing the spring to deform. At the same time, through the rotation of the threaded rod and bearing disk B, the threaded rod and bearing disk B will rotate synchronously, and the bristles on the outer wall of the stirring rod will be pushed against the outer wall of the rotating threaded rod. After being pushed, the bristles will rebound again due to their own elasticity, which will quickly push the powder, thereby improving the powder mixing efficiency. Furthermore, through the rapid rebound of the bristles, the powder adhering to the bristles will be shaken off, avoiding adhesion that affects the powder mixing effect.

[0019] 2. By setting up a flipping mechanism, when the threaded rod is driven by the gear to move in the tooth groove B, the threaded rod itself will also rotate. Through its own rotation and the thread of the threaded rod, the powder is more finely rotated and dispersed.

[0020] 3. By setting up a flipping mechanism, when the threaded rod rotates, the thread of the threaded rod drives the inner thread sleeve on the outer wall of the threaded rod to move through the thread. The inner thread sleeve is limited by a limiting plate, preventing it from rotating. Thus, the limiting plate moves quickly on the thread of the outer wall of the threaded rod with a large helix angle and a large pitch. The horizontal movement of the limiting plate quickly pushes the bristles on the outer wall of the stirring rod laterally. As the bristles are vertically pushed and rebounded by the threaded rod, they are also horizontally pushed and rebounded, improving the mixing effect of the powder. Furthermore, the limiting plate pushes the powder in the center of the barrel outward, while the outer powder is then crowded inward, achieving a flipping and mixing effect of the inner and outer layers of powder.

[0021] 4. By setting a flipping mechanism, and when the connecting sleeve is driven to rotate slowly for slow mixing, the round hole inside the dial plate allows the powder to pass through continuously. At this time, the dial plate is unable to overcome the elastic force of the spring and will not rotate. The powder is continuously separated and broken through the round hole. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of the present invention;

[0023] Figure 2 This is a schematic diagram of the connecting rod of the present invention;

[0024] Figure 3 This is a schematic diagram of the structure of the mixing mechanism of the present invention;

[0025] Figure 4 This is a schematic diagram of the structure of the mixing mechanism of the present invention;

[0026] Figure 5 For the present invention Figure 4Enlarged view of point A;

[0027] Figure 6 This is a schematic diagram of the disassembled structure of the mixing mechanism of the present invention;

[0028] Figure 7 This is a schematic diagram of the structure of the mixing mechanism of the present invention;

[0029] Figure 8 This is a schematic diagram of the structure of the mixing mechanism of the present invention;

[0030] Figure 9 For the three-dimensional transformation of the hybrid mechanism of the present invention Figure 1 ;

[0031] Figure 10 For the three-dimensional transformation of the hybrid mechanism of the present invention Figure 2 ;

[0032] Figure 11 For the present invention Figure 4 Enlarged view of point B;

[0033] Figure 12 This is a schematic diagram of the disassembled structure of the flipping mechanism of the present invention.

[0034] In the diagram: 1. Opening / closing lid; 2. Circular barrel; 3. Mixing mechanism; 301. Connecting sleeve; 302. Fixing sleeve; 303. Stirring rod; 304. Brush bristles; 305. Annular sleeve; 306. Sliding rod; 307. Rotating sleeve; 308. Paddle plate; 310. Turntable; 311. Gear groove A; 312. Gear; 313. Gear groove B; 314. Bearing disc A; 315. Bearing disc B; 316. Spring; 317. Circular ring; 4. Flipping mechanism; 401. Groove; 402. Circular hole; 403. Threaded rod; 404. Second fixing plate; 405. Internal threaded sleeve; 406. Limiting disc; 407. Telescopic rod; 408. Small spring; 5. Motor; 6. First fixing plate; 7. Connecting rod. Detailed Implementation

[0035] Example 1, please refer to Figure 1-3 The present invention provides a technical solution: a powder mixing pharmaceutical equipment for pharmaceutical engineering, including a cylindrical barrel 2, a first fixed plate 6 fixedly connected to the top of the cylindrical barrel 2, an opening and closing cover 1 hinged to the outer wall of the first fixed plate 6, a motor 5 fixedly connected to the top of the first fixed plate 6, a connecting rod 7 fixedly connected to the output end of the motor 5, and a mixing mechanism 3 provided on the outer wall of the connecting rod 7.

[0036] Hybrid mechanism 3 includes:

[0037] Connecting sleeve 301 is a hollow cylindrical structure. The inner wall of connecting sleeve 301 is fixedly connected to the outer wall of connecting rod 7. A fixing sleeve 302 is fixedly connected to the outer wall of connecting sleeve 301. A stirring rod 303 is fixedly connected to the outer wall of fixing sleeve 302. Brush bristles 304 are fixedly connected to the outer wall of stirring rod 303. Connecting sleeve 301 is used to rotate synchronously with connecting rod 7 and drive stirring rod 303 to rotate.

[0038] An annular sleeve 305 has a sliding rod 306 fixedly connected to its outer wall. One end of the sliding rod 306 is slidably connected to the inner wall of the cylindrical barrel 2. A rotating sleeve 307 is rotatably connected to the outer wall of the stirring rod 303. A lever 308 is fixedly connected to the outer wall of the rotating sleeve 307.

[0039] The powder to be mixed is placed into the cylindrical container 2 by opening the cover 1. Then, the motor 5 is started to drive the connecting rod 7 to rotate rapidly. The connecting rod 7 drives the connecting sleeve 301 to rotate synchronously. The rotation of the connecting sleeve 301 drives the fixed sleeve 302 and the stirring rod 303 to rotate. The rotation of the stirring rod 303 is used to fully stir the powder inside the cylindrical container 2 to make it evenly mixed. The brush bristles 304 on the outer wall are used to finely stir and separate the powder, so that the powder does not clump together and is more integrated. After the motor 5 controls the connecting rod 7 to rotate for a period of time, it automatically stops and starts to reverse. This process is repeated.

[0040] Example 2, please refer to Figure 1-10 Based on Embodiment 1, the present invention provides a technical solution: a bearing disk A314 is fixedly connected to the outer wall of the rotating sleeve 307, a turntable 310 is fixedly connected to the outer wall of the bearing disk A314, a toothed groove A311 is opened on the outer wall of the turntable 310, a toothed groove B313 is opened on the inner wall of the annular sleeve 305, and the outer wall of the bearing disk A314 is rotatably connected to the outer wall of the annular sleeve 305.

[0041] Gear 312 meshes with the inner wall of tooth groove B313 and tooth groove A311. Bearing disk B315 is rotatably connected to the outer wall of annular sleeve 305. Spring 316 is fixedly connected to the outer wall of bearing disk B315. Ring 317 is fixedly connected to one end of spring 316. The inner wall of ring 317 is fixedly connected to the outer wall of stirring rod 303. A flipping mechanism 4 is provided on the outside of stirring rod 303.

[0042] When the connecting sleeve 301 is driven to rotate rapidly, the stirring rod 303 also rotates rapidly in sync. The deflector 308 at the end of the stirring rod 303 is pushed by the reaction force of the powder inside the cylinder 2, thereby driving the deflector 308 to drive the rotating sleeve 307 to rotate on the outer wall of the stirring rod 303. The deflector 308 gradually changes from a vertical state to a horizontal state. As the rotating sleeve 307 rotates, it drives the rotating sleeve 307 and the bearing disk A314 to rotate synchronously. When the bearing disk A314 is driven to rotate, it will synchronously drive the turntable 310 on the outer wall of the stirring rod 303 to rotate. The toothed groove A311 on the outer wall of the turntable 310 continuously meshes with the outer wall of the gear 312, driving the gear 312 to rotate and move its position in the toothed groove B313 on the inner wall of the annular sleeve 305. Simultaneously, when gear 312 is driven to rotate and move, gear 312 will synchronously drive threaded rod 403 and bearing disk B315 to rotate. Bearing disk B315 rotates on the outer wall of annular sleeve 305, causing spring 316 to deform. At the same time, through the rotation of threaded rod 403 and bearing disk B315, threaded rod 403 and bearing disk B315 will rotate synchronously, and the bristles 304 on the outer wall of stirring rod 303 will be pushed against the outer wall of rotating threaded rod 403. After being pushed, the bristles 304 will rebound again due to their own elasticity, which will quickly push the powder, thereby improving the powder mixing efficiency. Furthermore, through the rapid rebound of bristles 304, the powder adhering to bristles 304 will be shaken off, avoiding adhesion that affects the powder mixing effect.

[0043] Example 3, please refer to Figure 1-12 Based on Embodiment 1 and Embodiment 2, the present invention provides a technical solution: the flipping mechanism 4 includes a groove 318, the groove 318 is opened inside the dial plate 308, the groove 318 and the inner wall of the dial plate 308 are provided with a round hole 402, the outer wall of the gear 312 is fixedly connected to a threaded rod 403, one end of the threaded rod 403 is fixedly connected to a second fixing plate 404, and the inner wall of the second fixing plate 404 is rotatably connected to the outer wall of the stirring rod 303.

[0044] The threaded rod 403 has an internal threaded sleeve 405 threaded to its outer wall. The inner threaded sleeve 405 has a limiting plate 406 fixedly connected to its outer wall. The limiting plate 406 has a small spring 408 fixedly connected to its outer wall. One end of the small spring 408 is fixedly connected to the outer wall of the second fixing plate 404. The second fixing plate 404 has a telescopic rod 407 fixedly connected to its outer wall. One end of the telescopic rod 407 is fixedly connected to the outer wall of the limiting plate 406.

[0045] The inner wall of groove 318 is an arc-shaped inclined surface, and the inner wall of hole 402 is a perfect circle.

[0046] The thread helix angle on the outer wall of threaded rod 403 is greater than 45 degrees, and the thread pitch on the outer wall of threaded rod 403 is relatively large.

[0047] The brush bristles are made of 304 rubber and are elastic.

[0048] When the threaded rod 403 is driven by the gear 312 to move in the tooth groove B313, the threaded rod 403 itself will also rotate. The threaded rod 403 will achieve a more refined rotation and dispersion effect on the powder through its own rotation and its own thread.

[0049] Meanwhile, since the annular sleeve 305 is fixed by the sliding rod 306, and one end of the sliding rod 306 is slidably connected to the inner wall of the cylinder 2, the annular sleeve 305 is limited and cannot rotate. Therefore, the rotation of the turntable 310 will drive the gear 312 to rotate along the tooth groove B313 on the inner wall of the annular sleeve 305.

[0050] Furthermore, as the threaded rod 403 rotates, the thread of the threaded rod 403 drives the inner threaded sleeve 405 on the outer wall of the threaded rod 403 to move along the thread. The inner threaded sleeve 405 is limited by the limiting plate 406, preventing it from rotating. Thus, the limiting plate 406 moves quickly on the thread of the outer wall of the threaded rod 403 with a large helix angle and a large pitch. The horizontal movement of the limiting plate 406 quickly pushes the bristles 304 on the outer wall of the stirring rod 303 laterally. As the bristles 304 are vertically pushed and rebounded by the threaded rod 403, they are also horizontally pushed and rebounded, improving the mixing effect of the powder. The limiting plate 406 pushes the powder in the center of the cylinder 2 outward, while the outer powder is then crowded inward, achieving a layering and mixing effect of the inner and outer powders.

[0051] Furthermore, when the connecting sleeve 301 is driven to rotate slowly for slow mixing, the round hole 402 inside the dial plate 308 allows the powder to pass through continuously. At this time, the dial plate 308 is unable to overcome the elastic force of the spring 316 and will not rotate. The powder is continuously separated and crushed through the round hole 402. When the connecting sleeve 301 rotates at a faster speed, and the amount of powder passing through the round hole 402 is insufficient, the powder will push the groove 318 opened inside the dial plate 308 and be multiplied by the groove 318, thereby improving the pushing effect of the powder on the dial plate 308. When the dial plate 308 drives the rotating sleeve 307 and the bearing disk A314 to rotate, it drives the rotating disk 310 to rotate synchronously. The rotation of the rotating disk 310 causes the gear 312 to drive the threaded rod 403 and the bearing disk B315 to rotate, thereby overcoming the elastic force of the spring 316 and causing it to deform.

[0052] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A powder mixing pharmaceutical equipment for pharmaceutical engineering, comprising a cylindrical drum (2), wherein a first fixing plate (6) is fixedly connected to the top of the cylindrical drum (2), an opening and closing cover (1) is hinged to the outer wall of the first fixing plate (6), and a motor (5) is fixedly connected to the top of the first fixing plate (6), characterized in that: The output end of the motor (5) is fixedly connected to a connecting rod (7), and a mixing mechanism (3) is provided on the outer wall of the connecting rod (7). The hybrid mechanism (3) includes: The connecting sleeve (301) is a hollow cylindrical structure. The inner wall of the connecting sleeve (301) is fixedly connected to the outer wall of the connecting rod (7). A fixing sleeve (302) is fixedly connected to the outer wall of the connecting sleeve (301). A stirring rod (303) is fixedly connected to the outer wall of the fixing sleeve (302). A brush (304) is fixedly connected to the outer wall of the stirring rod (303). The connecting sleeve (301) is used to rotate synchronously with the connecting rod (7) and drive the stirring rod (303) to rotate. An annular sleeve (305) is provided with a sliding rod (306) fixedly connected to its outer wall. One end of the sliding rod (306) is slidably connected to the inner wall of the cylindrical barrel (2). A rotating sleeve (307) is rotatably connected to the outer wall of the stirring rod (303). A lever plate (308) is fixedly connected to the outer wall of the rotating sleeve (307). The outer wall of the rotating sleeve (307) is fixedly connected to a bearing disk A (314), the outer wall of the bearing disk A (314) is fixedly connected to a turntable (310), the outer wall of the turntable (310) is provided with a toothed groove A (311), the inner wall of the annular sleeve (305) is provided with a toothed groove B (313), and the outer wall of the bearing disk A (314) is rotatably connected to the outer wall of the annular sleeve (305). The toothed groove B (313) meshes with the inner wall of the toothed groove A (311) with a gear (312). The outer wall of the annular sleeve (305) is rotatably connected to a bearing disk B (315). The outer wall of the bearing disk B (315) is fixedly connected to a spring (316). One end of the spring (316) is fixedly connected to a ring (317). The inner wall of the ring (317) is fixedly connected to the outer wall of the stirring rod (303). The stirring rod (303) is provided with a flipping mechanism (4) on the outside. The flipping mechanism (4) includes a groove (318) which is opened inside the dial plate (308). The groove (318) and the inner wall of the dial plate (308) are provided with a round hole (402). A threaded rod (403) is fixedly connected to the outer wall of the gear (312). A second fixing plate (404) is fixedly connected to one end of the threaded rod (403). The inner wall of the second fixing plate (404) is rotatably connected to the outer wall of the stirring rod (303). The bristles (304) are made of rubber and are elastic. When the connecting sleeve (301) is driven to rotate rapidly, the stirring rod (303) also rotates rapidly in sync. The deflector (308) at the end of the stirring rod (303) is pushed by the reaction force of the powder inside the barrel (2), thereby pushing the deflector (308) to drive the rotating sleeve (307) to rotate on the outer wall of the stirring rod (303). The deflector (308) gradually changes from a vertical state to a horizontal state. As the rotating sleeve (307) rotates, it drives the rotating sleeve (307) and the bearing disk A (314) to rotate synchronously. When the bearing disk A (314) is driven to rotate, it will drive the turntable (310) on the outer wall of the stirring rod (303) to rotate synchronously. The toothed groove A (311) on the outer wall of the turntable (310) continuously meshes with the outer wall of the gear (312), driving the gear (312) to move in the toothed groove B (313) on the inner wall of the annular sleeve (305). When the gear (312) is rotated and moved, the gear (312) will drive the threaded rod (403) and bearing disk B (315) to rotate synchronously. The bearing disk B (315) rotates on the outer wall of the annular sleeve (305), and causes the spring (316) to deform. At the same time, the rotation of the threaded rod (403) and bearing disk B (315) will drive the threaded rod (403) and bearing disk B (315) to rotate synchronously. The bristles (304) on the outer wall of the stirring rod (303) will be pushed against the outer wall of the rotating threaded rod (403). After the bristles (304) are pushed, they will rebound again with their own elasticity, which will quickly push the powder, improve the powder mixing efficiency, and shake off the powder adhering to the bristles (304) through the rapid rebound of the bristles (304).

2. The powder mixing pharmaceutical equipment for pharmaceutical engineering according to claim 1, characterized in that: The threaded rod (403) is threaded to the outer wall with an inner threaded sleeve (405). The inner threaded sleeve (405) is fixedly connected to the outer wall with a limiting plate (406). The limiting plate (406) is fixedly connected to the outer wall with a small spring (408). One end of the small spring (408) is fixedly connected to the outer wall of the second fixing plate (404). The second fixing plate (404) is fixedly connected to the outer wall with a telescopic rod (407). One end of the telescopic rod (407) is fixedly connected to the outer wall of the limiting plate (406).

3. The powder mixing pharmaceutical equipment for pharmaceutical engineering according to claim 2, characterized in that: The inner wall of the groove (318) is an arc-shaped inclined surface, and the inner wall of the circular hole (402) is a perfect circle.

4. A powder mixing pharmaceutical equipment for pharmaceutical engineering according to claim 3, characterized in that: The thread helix angle on the outer wall of the threaded rod (403) is greater than forty-five degrees.

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