blood pump

Abstract

The present application relates to a blood pump, which includes a primary pumping device, a first catheter, a secondary pumping device, and a second catheter connected in sequence; wherein the primary pumping device is provided with a first inlet and a first outlet; the secondary pumping device is provided with a second inlet and a second outlet, and the second inlet is provided on the peripheral wall of the secondary pumping device. The blood pump of the present application utilizes a primary pumping device and a secondary pumping device to achieve two-stage drive, greatly improving the drive of the blood pump. In addition, by providing the second inlet on the peripheral wall of the secondary pumping device, the second inlet is prevented from occupying the space on the distal end face of the secondary pumping device, so that the proximal end of the first catheter is connected to the distal end of the secondary pumping device, without expanding the diameter of the distal end of the secondary pumping device, so that the diameter of the distal end of the secondary pumping device is smaller, reducing the risk of the distal end of the secondary pumping device colliding and damaging the blood vessel wall, and reducing the difficulty of implantation.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a blood pump. Background Art

[0002] Blood pumps, as heart assist devices, are typically used to partially or completely replace the heart's work to assist the patient's blood circulation. However, traditional blood pumps often suffer from drawbacks such as insufficient power to drive blood flow. Summary of the Invention

[0003] Based on this, the present application provides a blood pump, aiming to solve the problem of insufficient driving force of traditional blood pumps.

[0004] In one embodiment, the blood pump includes a primary pumping device, a first conduit, a secondary pumping device and a second conduit connected in sequence; wherein the primary pumping device is provided with a first inlet and a first outlet; the secondary pumping device is provided with a second inlet and a second outlet, and the second inlet is arranged on the outer peripheral wall of the secondary pumping device.

[0005] In one embodiment, a connecting end is provided at the distal end of the secondary pumping device; a first sleeve portion is provided at the proximal end of the first conduit, and the first sleeve portion is sleeved on the outer circumference of the connecting end and fixedly connected to the connecting end.

[0006] In one embodiment, the first sleeve portion is configured to be trumpet-shaped, and the inner diameter of the first sleeve portion is configured to gradually increase in the direction along the first conduit to the secondary pumping device; the connecting end includes a first diameter-reducing circumferential surface, and the first diameter-reducing circumferential surface is configured to imitate the shape of the inner circumferential surface of the first sleeve portion so as to be adaptively connected to the first sleeve portion.

[0007] In one embodiment, the proximal end of the first catheter is further provided with a fixing cover, which is sleeved on the outer periphery of the first sleeve portion. The fixing cover is provided with a reducing opening and an expanding opening, and the periphery of the expanding opening is fixedly connected to the connecting end; the periphery of the reducing opening is sleeved on the first catheter, and the diameter of the reducing opening is smaller than the diameter of the first sleeve portion.

[0008] In one embodiment, the fixing cover is made of metal material, the periphery of the expanded diameter opening of the fixing cover is welded to the connecting end; and the outer peripheral surface of the fixing cover and the outer peripheral surface of the connecting end are smoothly transitioned and docked.

[0009] In one embodiment, the distal end of the second catheter is provided with a second sleeve portion, and the proximal end of the secondary pumping device is provided with a fixing pin for the second sleeve portion to be sleeved and fixed; the interior of the secondary pumping device is also provided with a fixing tube, one end of the fixing tube is inserted and fixed to the fixing pin, and the other end is inserted and fixed to the connecting end.

[0010] In one embodiment, the primary pumping device includes a casing assembly, the casing assembly including a primary casing, an outlet pipe provided with the first outlet, and an inlet pipe provided with the first inlet, the primary casing connecting the outlet pipe and the inlet pipe; the secondary pumping device includes a secondary casing, the secondary casing provided with the second inlet and the second outlet; wherein the primary casing is an elastic tube; and the secondary casing is a rigid tube.

[0011] In one embodiment, the second inlet is provided on the outer peripheral wall of the distal end of the secondary sleeve; the second inlet comprises a plurality of inlet holes, and the plurality of inlet holes are spaced apart and distributed along the circumference of the secondary sleeve.

[0012] In one embodiment, a first flushing pipe is provided inside the first conduit to supply flushing liquid to the primary pumping device, and a second flushing pipe is provided inside the second conduit to supply flushing liquid to the secondary pumping device; the secondary pumping device is provided with an intermediate channel, which extends along the axial direction of the secondary pumping device and passes through the secondary pumping device to connect the first flushing pipe and the second flushing pipe.

[0013] In one embodiment, the secondary pumping device includes a secondary motor, a secondary casing, and a secondary impeller arranged in the secondary casing; wherein, the secondary motor includes a rotating shaft, one end of the rotating shaft is rotatably passed through the interior of the secondary motor, and the other end passes through the secondary impeller to be rotatably connected to the distal end of the secondary casing, and the rotating shaft can drive the secondary impeller to rotate; the interior of the rotating shaft is hollow to form at least a part of the intermediate channel.

[0014] In one embodiment, the secondary pumping device includes a secondary motor, a fixed tube, a secondary casing, and a secondary impeller arranged in the secondary casing; wherein, one end of the fixed tube is fixed to the inside of the secondary motor, and the other end passes through the secondary impeller to be fixed to the distal end of the secondary casing, and the interior of the fixed tube is hollow to form at least a part of the intermediate channel; the secondary impeller is capable of rotating around the fixed tube.

[0015] In one embodiment, the secondary motor includes a housing and a stator, a rotor, and a rotating shaft mounted within the housing; wherein the rotating shaft is sleeved around the outer periphery of the fixed tube, and a distal end of the rotating shaft extends out of the housing to be connected and fixed to the secondary impeller, and the rotating shaft is rotatable relative to the fixed tube; the rotor is connected and fixed to the outer periphery of the rotating shaft; and the stator is capable of generating a magnetic field to drive the rotor to rotate.

[0016] Alternatively, the secondary motor includes a housing and a stator and a rotor installed in the housing; the rotor is connected to the secondary impeller, and the stator can generate a magnetic field to drive the rotor to rotate.

[0017] In one embodiment, at least one of the inner circumference of the rotating shaft and the outer circumference of the fixing tube is made of ceramic.

[0018] And / or, a first gap is formed between the inner circumference of the rotating shaft and the outer circumference of the fixed tube, and the first gap communicates with the second flushing tube and the lumen of the secondary sleeve;

[0019] And / or, a magnetic ring is provided on one of the inner circumference of the rotating shaft and the outer circumference of the fixed tube, and a magnet is provided on the other, and the magnetic ring and the magnet repel each other so that the inner circumference of the rotating shaft is suspended relative to the outer circumference of the fixed tube.

[0020] In one embodiment, the diameter D3 of the fixed tube is smaller than the outer diameter D1 of the first conduit;

[0021] and / or, the outer diameter D1 of the first conduit is smaller than the outer diameter D2 of the second conduit;

[0022] And / or, the outer diameter D2 of the second conduit is less than twice the outer diameter D1 of the first conduit.

[0023] In one embodiment, the length of the first catheter is 180 mm to 300 mm, so that the secondary pumping device can be located in the descending portion of the aorta.

[0024] The blood pump provided by the above solution, by providing a primary pumping device, a first catheter, a secondary pumping device, and a second catheter connected in sequence, achieves a two-stage drive using the primary and secondary pumping devices, significantly improving the driving force of the blood pump and increasing the blood pumping volume. Furthermore, because the blood pump of the present application has the second inlet of the secondary pumping device disposed on the peripheral wall of the secondary pumping device, compared to disposing the second inlet on the distal end face of the secondary pumping device, the blood pump of the present application can avoid the second inlet occupying space on the distal end face of the secondary pumping device, thereby facilitating the connection between the proximal end of the first catheter and the distal end of the secondary pumping device. This eliminates the need to expand the diameter of the distal end of the secondary pumping device, resulting in a smaller diameter at the distal end of the secondary pumping device, thereby reducing the risk of the distal end of the secondary pumping device colliding with and damaging the blood vessel wall, and simplifying implantation difficulty. Furthermore, blood can enter through the second inlet on the peripheral surface of the secondary pumping device, thereby reducing the impact of blood flow at the second inlet on the connection between the first catheter and the secondary pumping device, and preventing the proximal end of the first catheter from loosening. In addition, since the area of ​​the outer wall of the secondary pumping device is larger than the area of ​​its distal end face, the inlet area of ​​the second inlet can be designed to be larger, which is conducive to the blood in the aorta entering the secondary pumping device through the second inlet, and can greatly increase the blood flow pumped by the secondary pumping device. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 Schematic diagram of the structure of a blood pump in one embodiment of the present application.

[0026] Figure 2 This is a schematic diagram of a blood pump inserted into a portion of the aorta in one embodiment of the present application.

[0027] Figure 3 for Figure 2 Cross-sectional view of a blood pump inserted into part of the aorta.

[0028] Figure 4 for Figure 1 Schematic diagram of the connection between the secondary pumping device and the first and second conduits.

[0029] Figure 5 for Figure 4 Exploded view of the assembly structure of the secondary pumping device, the first conduit and the second conduit.

[0030] Figure 6 for Figure 1 Schematic diagram of the connection between the secondary pumping device and the first and second conduits.

[0031] Figure 7 for Figure 6 Exploded view of the secondary pumping unit in Figure 1.

[0032] Figure 8This is a schematic diagram of another embodiment of the secondary pumping device in one embodiment of the present application.

[0033] Figure 9 for Figure 8 Sectional view of the secondary pumping unit along AA.

[0034] Figure 10 for Figure 9 The enlarged schematic diagram of P1 in FIG.

[0035] Figure 11 for Figure 9 The enlarged schematic diagram of P2 in FIG.

[0036] Figure 12 for Figure 8 Sectional view of the secondary pumping device along BB.

[0037] Figure 13 Schematic diagram of the assembly of the rotating shaft and the fixed pipe of the secondary pumping device in one embodiment of the present application.

[0038] Figure 14 for Figure 13 A transverse cross-sectional view showing one of the mating configurations of the rotating shaft and the fixed tube.

[0039] Figure 15 for Figure 13 A transverse cross-sectional view showing another matching method between the rotating shaft and the fixed tube.

[0040] Figure 16 Schematic diagram of the structure of the main pumping device in one embodiment of the present application.

[0041] Description of reference numerals:

[0042]

[0043] DETAILED DESCRIPTION

[0044] To make the above-mentioned objects, features, and advantages of the present application more clearly understood, the specific embodiments of the present application are described in detail below with reference to the accompanying drawings. The following description sets forth many specific details to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways than those described herein, and those skilled in the art can make similar improvements without violating the scope of the present application. Therefore, the present application is not limited to the specific embodiments disclosed below.

[0045] In the description of this application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing this application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0046] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Therefore, a feature specified as "first" or "second" may explicitly or implicitly include at least one of such features. In the description of this application, if the term "plurality" appears, "plurality" means at least two, for example, two, three, etc., unless otherwise specifically defined.

[0047] In this application, unless otherwise specified or limited, the terms "mounted," "connected," "connected," "fixed," etc., should be interpreted broadly. For example, these terms may refer to fixed connections, removable connections, or integration; mechanical connections or electrical connections; direct connections or indirect connections through an intermediary; and internal communication between two components or interaction between two components, unless otherwise specified. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances.

[0048] In this application, unless otherwise expressly specified or limited, if a first feature is described as being "above" or "below" a second feature, or similar descriptions, this may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Furthermore, when a first feature is described as being "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is described as being "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.

[0049] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only embodiment.

[0050] This application provides an embodiment of a blood pump. The blood pump can be used to assist blood flow in the right ventricle or the left ventricle, without limitation. To avoid redundancy, the following description uses the blood pump's application in assisting blood flow in the right ventricle as an example. For ease of description, "proximal" is defined as the end of an interventional medical device closer to the operator, and "distal" is defined as the end of an interventional medical device farther from the operator, but this is not intended to be limiting.

[0051] See also Figures 1 to 3 The blood pump 10 includes a primary pumping device 100, a first conduit 200, a secondary pumping device 300, and a second conduit 400, which are connected in sequence. The primary pumping device 100 has a first inlet 101 and a first outlet 102; the secondary pumping device 300 has a second inlet 301 and a second outlet 302, with the second inlet 301 being located on the outer circumference of the secondary pumping device 300.

[0052] Specifically, the distal end of the primary pumping device 100 can be connected to a pigtail tube (not shown), which supports and positions the primary pumping device 100 against the inner wall of the heart. The proximal end of the primary pumping device 100 is connected to the distal end of the first catheter 200, which is in turn connected to the distal end of the secondary pumping device 300. The proximal end of the secondary pumping device 300 is connected to the distal end of the second catheter 400.

[0053] After the blood pump 10 is introduced into the patient's body, the primary pumping device 100 passes through the valve from the aorta 20 and partially extends into the ventricle, so that the first inlet 101 of the primary pumping device 100 is located in the ventricle, and the first outlet 102 of the primary pumping device 100 is located in the aorta 20; the secondary pumping device 300 and the first catheter 200 are located in the aorta 20; the second catheter 400 extends from the secondary pumping device 300 to the outside of the patient's body. When the blood pump 10 is started, the blood in the ventricle flows into the primary pumping device 100 from the first inlet 101, is accelerated by the primary pumping device 100, and flows out from the first outlet 102 to the ascending part 22 of the aorta 20, and then flows along the ascending part 22 of the aorta 20 toward the aortic arch 22; then, the blood meets the secondary pumping device 300 and is sucked into it by the second inlet 301 of the secondary pumping device 300. The secondary pumping device 300 accelerates the sucked blood again and discharges it from the second outlet 302 to the descending part 23 of the aorta 20, thereby accelerating the blood flow, allowing the blood to flow smoothly through the aortic arch 22, and accelerating blood circulation.

[0054] Thus, the blood pump 10 of the present application is configured with a primary pumping device 100, a first conduit 200, a secondary pumping device 300, and a second conduit 400, and the primary pumping device 100, the first conduit 200, the secondary pumping device 300, and the second conduit 400 are connected in sequence, and the blood is accelerated at least twice by the primary pumping device 100 and the secondary pumping device 300, so that the blood pump 10 has a dual-stage drive function, which can effectively enhance the driving force of the blood pump 10 and increase the blood flow rate pumped by the blood pump 10. Due to the presence of the secondary pumping device 300, the secondary pumping device 300 generates a negative pressure at the aortic arch 22, accelerating the blood in the ascending portion 22 of the aorta 20 to flow toward the descending portion 23 of the aorta 20, thereby increasing the blood flow rate.

[0055] It is understood that because the blood pump 10 of the present application includes a primary pumping device 100 and a secondary pumping device 300, while ensuring that the total pumping power of the blood pump 10 is no less than the pumping power of a conventional blood pump 10, the pumping power of a single pumping device (such as the primary pumping device 100 or the secondary pumping device 300) can be appropriately reduced to reduce the axial dimension of the single pumping device, thereby reducing the length of the primary pumping device 100 for easier implantation in the patient. In particular, reducing the length of the primary pumping device 100 can significantly reduce the difficulty of passing the primary pumping device 100 through the aortic arch 22.

[0056] In particular, since the second inlet 301 of the blood pump 10 of the present application is disposed on the outer peripheral wall of the secondary pumping device 300, the second inlet 301 can have a larger inlet area, thereby facilitating the blood in the aorta 20 to enter the secondary pumping device 300 through the second inlet 301, thereby significantly increasing the blood flow rate pumped by the secondary pumping device 300. Furthermore, since the proximal end of the first catheter 200 of the blood pump 10 is connected to the distal end of the secondary pumping device 300, if the second inlet 301 of the secondary pumping device 300 is also disposed at the distal end of the secondary pumping device 300, not only would the diameter of the distal end of the secondary pumping device 300 be increased, increasing the risk of the distal end of the secondary pumping device 300 colliding and damaging the blood vessel wall, but the blood flow at the second inlet 301 would easily scour the connection between the first catheter 200 and the secondary pumping device 300, potentially causing the first catheter 200 to fall off. Therefore, the blood pump 10 of the present application sets the second inlet 301 on the outer wall of the secondary pumping device 300, which not only eliminates the need to expand the diameter of the distal end of the secondary pumping device 300, reducing the risk of the distal end of the secondary pumping device 300 colliding and damaging the blood vessel wall, but also reduces the erosion of the blood flow at the second inlet 301 on the connection between the first catheter 200 and the secondary pumping device 300, preventing the proximal end of the first catheter 200 from loosening.

[0057] like Figure 3 As shown, in some embodiments, the length of first catheter 200 can be selected to be between 180 mm and 300 mm. This length of first catheter 200 allows secondary pumping device 300 to enter descending portion 23 of aorta 20 and be positioned above the renal arteries, thereby increasing renal artery blood flow. The length of first catheter 200 can be, but is not limited to, 190 mm, 200 mm, 220 mm, 250 mm, 280 mm, 290 mm, and the like.

[0058] See also Figure 4 and Figure 5 In some embodiments, a first flushing channel is provided within the primary pumping device 100 for injecting flushing fluid (e.g., saline) to prevent blood from entering the primary pumping device 100 and causing thrombosis, and also to dissipate heat from the primary pumping device 100. A second flushing channel is provided within the secondary pumping device 300 for injecting flushing fluid (e.g., saline) to prevent blood from entering the secondary pumping device 300 and causing thrombosis, and also to dissipate heat from the secondary pumping device 300. To this end, a first flushing tube 220 for supplying flushing fluid to the primary pumping device 100 is provided within the first catheter 200; and a second flushing tube 420 for supplying flushing fluid to the secondary pumping device 300 is provided within the second catheter 400.

[0059] In this embodiment, to prevent the first flushing pipe 220 from passing through the secondary pumping device 300, an intermediate passage 303 is provided within the secondary pumping device 300, extending axially through the secondary pumping device 300. The intermediate passage 303 connects the first flushing pipe 220 with the second flushing pipe 420. In other words, the distal end of the second flushing pipe 420 is connected to both the second flushing channel and the intermediate channel of the secondary pumping device 300. This design allows a portion of the flushing fluid supplied by the second flushing pipe 420 to enter the second flushing channel for supply to the secondary pumping device 300, while the remaining portion is transported through the intermediate passage 303 to the first flushing pipe 220, and then supplied to the primary pumping device 100 through the first flushing pipe 220.

[0060] In some embodiments, a first electrical wire (not shown) is further disposed within the first conduit 200. The distal end of the first electrical wire is connected to the primary pumping device 100 to provide electrical energy to the primary pumping device 100. Preferably, the first electrical wire and the first irrigation tube 220 are disposed within the first conduit 200 without interfering with each other. In this embodiment, the first electrical wire passes through the second conduit 400, the intermediate channel 303 of the secondary pumping device 300, and the first conduit 200 from its proximal end to its distal end before being connected to the primary pumping device 100. A second electrical wire (not shown) is also disposed within the second conduit 400. The distal end of the second electrical wire is connected to the secondary pumping device 300 to provide electrical energy to the secondary pumping device 300. Preferably, the second electrical wire and the second irrigation tube 420 are disposed within the first conduit 200 without interfering with each other. Since the first electrical wire, the second electrical wire, and the second irrigation tube 420 all need to pass through the second conduit 400, only the first electrical wire and the first irrigation tube 220 need to pass through the first conduit 200. In some embodiments, the outer diameter D1 of the first catheter 200 is smaller than the outer diameter D2 of the second catheter 400. More preferably, the outer diameter D2 of the second catheter 400 is less than twice the outer diameter D1 of the first catheter 200 to prevent the outer diameter D2 of the second catheter 400 from being too large and affecting its implantation in the human body.

[0061] It is worth mentioning that if the first catheter 200 is passed through the secondary pumping device 300, there may be multiple defects: ① The diameter of the first catheter 200 needs to be reduced, and the inner cavity of the first catheter 200 is difficult to accommodate the wires of the main pumping device 100 and the first flushing tube 220, and the strength of the first catheter 200 will be too small, making it difficult to manipulate and guide the secondary pumping device 300 through the blood vessel 200 and into the heart; ② If the diameter of the first catheter 200 is not reduced, the diameter of the secondary pumping device 300 needs to be increased, which will cause the volume of the secondary pumping device 300 to increase, thereby increasing the difficulty of implantation into the human body; ③ The first catheter 200 is likely to interfere with the internal components of the secondary pumping device 300 during the process of passing through the secondary pumping device 300, and the gap between the outer periphery of the first catheter 200 and the secondary pumping device 300 is difficult to seal, which is prone to blood seepage and thrombosis accidents.

[0062] Compared with the above-mentioned method of inserting the first catheter 200, the proximal end of the first catheter 200 of the present application is only connected to the distal end of the secondary pumping device 300, and the flushing fluid or wire is transmitted through the intermediate channel 303 inside the secondary pumping device 300, thereby overcoming at least one of the above-mentioned three defects. There is no need to reduce the diameter of the first catheter 200, nor to increase the diameter of the secondary pumping device 300, so that the secondary pumping device 300 has a smaller volume, thereby reducing the difficulty of implantation.

[0063] See also Figures 4 to 6 In some embodiments, in order to facilitate the connection between the first catheter 200 and the distal end of the secondary pumping device 300, the distal end of the secondary pumping device 300 is provided with a connecting end 324; the proximal end of the first catheter 200 is provided with a first sleeve portion 210, which is sleeved on the outer peripheral surface of the connecting end 324 and is fixedly connected to the connecting end 324.

[0064] Specifically, the secondary pumping device 300 includes a secondary sleeve 320 with a larger diameter in the middle and smaller diameters at both ends. The larger diameter portion accommodates the larger diameter secondary impeller 330. The secondary sleeve 320 is provided with a second inlet 301 and a second outlet 302. The proximal portion of the secondary sleeve 320 is connected to the second catheter 400, and the distal portion of the secondary sleeve 320 is provided with the connecting end 324. The second inlet 301 is adjacent to the connecting end 324 and includes multiple outlet holes. Multiple connecting posts 325 are formed between adjacent outlet holes, with the distal end of each connecting post 325 fixedly connected to the connecting end 324. The first sleeve 210 is sleeved onto the outer circumference of the connecting end 324, with the two portions in surface-to-surface contact, effectively sealing the proximal end of the first catheter 200 and preventing blood from seeping into the first catheter 200.

[0065] See also Figures 5 to 7In some embodiments, the first sleeve portion 210 is configured to be trumpet-shaped, and the inner diameter of the first sleeve portion 210 is gradually increased in the direction along the first conduit 200 to the secondary pumping device 300; the connecting end 324 includes a first diameter-reducing circumferential surface 324a, and the first diameter-reducing circumferential surface 324a is configured to imitate the shape of the inner circumferential surface of the first sleeve portion 210 so as to be adaptively connected to the first sleeve portion 210.

[0066] Specifically, the connecting end 324 includes a tapered portion 3241 and a spherical portion 3242. The spherical portion 3242 is used to direct fluid toward the second inlet 301. The tapered portion 3241 has a conical or truncated cone-shaped structure. A first reduced diameter surface 324a is formed on the outer circumference of the tapered portion 3241 to fit snugly with the first sleeve portion 210. The first sleeve portion 210 is sleeved onto the outer portion of the first reduced diameter surface 324a. The inner circumference of the first sleeve portion 210 is connected to the first reduced diameter surface 324a. In this embodiment, the first sleeve portion 210 and the first reduced diameter surface 324a are glued together. The tighter the fit along the direction from the secondary pumping device 300 to the first conduit 200, the greater the sealing performance of the proximal end of the first conduit 200.

[0067] See also Figures 7 to 9 In some embodiments, a fixing cap 350 is further disposed at the proximal end of the first conduit 200. The fixing cap 350 has an annular structure and is sleeved around the outer periphery of the first sleeve portion 210. The fixing cap 350 has a reduced diameter opening 351 and an expanded diameter opening 352. The periphery of the expanded diameter opening 352 is fixedly connected to the connecting end 324, while the periphery of the reduced diameter opening 351 is sleeved around the first conduit 200. The diameter of the reduced diameter opening 351 is smaller than that of the first sleeve portion 210. When the fixing cap 350 connects the secondary pumping device 300 to the first conduit 200, the fixing cap 350 sleeves around the outer periphery of the first sleeve portion 210, which sleeves around the first reduced diameter peripheral surface 324a. The fixing cap 350 is fixedly connected to the first reduced diameter peripheral surface 324a, thereby strengthening the connection between the first conduit 200 and the secondary pumping device 300. In this embodiment, the fixing cover 350 is made of metal material, the periphery of the enlarged diameter opening 352 of the fixing cover 350 is welded to the connecting end 324 , and the outer peripheral surface of the fixing cover 350 and the outer peripheral surface of the connecting end 324 are smoothly transitioned and docked.

[0068] In some embodiments, the junction between the conical portion 3241 and the spherical portion 3242 of the connecting end 324 forms a joint, and the diameter of the joint is the maximum diameter of the spherical portion. The joint is connected to the distal end of the connecting post, allowing the spherical portion 3242 to extend into the interior of the secondary cannula 320, thereby guiding blood to flow along the wall and enter the secondary cannula 320 through the second inlet 301. Preferably, the spherical portion 3242 has a hemispherical structure.

[0069] In some embodiments, the second outlet 302 includes a plurality of outlet holes that are circumferentially spaced apart along the circumference of the secondary sleeve 320. The circumferential width of each outlet hole decreases from the distal end to the proximal end.

[0070] See also Figures 7 to 9 In some embodiments, a fixing pin 315 is provided at the proximal end of the secondary pumping device 300, and a second sleeve portion 410 is provided at the distal end of the second conduit 400. The second sleeve portion 410 is sleeved onto the proximal end of the fixing pin 315. Specifically, the diameter of the second sleeve portion 410 increases from the proximal end to the distal end. The outer periphery of the fixing pin 315 is also wrapped with a positioning cap 317. The outer periphery of the positioning cap 317 has a second diameter-reducing surface that is contoured to the inner periphery of the second sleeve portion 410, so that the second sleeve portion 410 fits snugly with the second diameter-reducing surface.

[0071] See also Figures 9 to 11 There are various possible designs for forming the intermediate passage 303 of the secondary pumping device 300. For example, the rotating shaft 314 of the secondary pumping device 300 can be configured as a hollow tube, so that the intermediate passage 303 is formed by utilizing the inner cavity of the rotating shaft 314. Alternatively, a fixed tube 340 can be added to the secondary pumping device 300, passing through the rotating shaft 314 and also configured as a hollow tube, so that the inner cavity of the fixed tube 340 forms the intermediate passage 303.

[0072] See also Figures 9 to 11 In some embodiments, the secondary pumping device 300 includes a secondary motor 310, a fixed tube 340, a secondary sleeve 320, and a secondary impeller 330 disposed in the secondary sleeve 320; wherein one end of the fixed tube 340 is fixed to the inside of the secondary motor 310, and the other end passes through the secondary impeller 330 to be fixed to the distal end of the secondary sleeve 320; the secondary impeller 330 is capable of rotating around the fixed tube 340; the interior of the fixed tube 340 is hollow to form at least a portion of the intermediate channel 303.

[0073] Specifically, the proximal end of the secondary motor 310 is fixedly connected to the second conduit 400; the distal end of the secondary motor 310 is fixedly connected to the proximal end of the secondary sleeve 320; and the distal end of the secondary sleeve 320 is fixedly connected to the first conduit 200. The second inlet 301 and the second outlet 302 are both provided on the secondary sleeve 320. The secondary impeller 330 is disposed within the secondary sleeve 320 and adjacent to the second outlet 302. The fixed tube 340 has a first end 341 and a second end 342, and the second end 342 is far away from the first end 341; wherein the first end 341 is passed through the interior of the secondary motor 310 and fixed to the proximal end of the secondary motor 310 (such as the fixing pin 315), so that the first end 341 is connected to the second flushing tube 420 fixed to the proximal end of the secondary motor 310; the second end 342 passes through the distal end of the secondary motor 310, passes through the secondary impeller 330, passes through the tube cavity of the secondary sleeve 320 and is fixed to the distal end of the secondary sleeve 320, so that the second end 342 is connected to the first flushing tube 220 fixed to the distal end of the secondary motor 310.

[0074] It is understood that the distal end of the primary pumping device 100 can be positioned within the ventricle via a pigtail tube, while the central portion of the primary pumping device 100 can be positioned by being clamped by the valve. Regarding the secondary pumping device 300, the secondary pumping device 300 is entirely positioned within the artery. The second catheter 400 and the first catheter 200 are typically relatively flexible, and therefore may not be sufficient to stably support the secondary pumping device 300. In the present application, a fixing tube 340 is disposed within the secondary pumping device 300. This fixing tube 340 supports the secondary pumping device 300, allowing the rotating shaft 314 and the secondary impeller 330 of the secondary pumping device 300 to rotate stably, thereby enhancing the stability of the secondary pumping device 300. Optionally, the fixing tube 340 is made of metal. The diameter D3 of the fixing tube 340 is smaller than the outer diameter D1 of the first catheter 200.

[0075] See also Figure 7 、 Figure 9 and Figure 10 Furthermore, the secondary motor 310 includes a housing 311 and a stator 312, a rotor 313 and a rotating shaft 314 installed in the housing 311; wherein the rotating shaft 314 is sleeved on the outer circumference of the fixed tube 340, and the distal end of the rotating shaft 314 passes through the housing 311 to be connected and fixed to the secondary impeller 330, and the rotating shaft 314 can rotate relative to the fixed tube 340; the rotor 313 is connected and fixed to the outer circumferential surface of the rotating shaft 314; the stator 312 can generate a magnetic field to drive the rotor 313 to rotate.

[0076] The rotating shaft 314 is rotatably mounted on the outer circumference of the fixed tube 340. The distal end of the rotating shaft 314 extends through the housing 311 to be fixedly connected to the secondary impeller 330. The rotor 313 is fixedly connected to the outer circumference of the rotating shaft 314, and the stator 312 surrounds the outer circumference of the rotating shaft 314. The rotor 313, stator 312, sensor 360, and secondary impeller 330 are all connected to the outer circumference of the rotating shaft 314. The rotor 313, sensor 360, and stator 312 are all located inside the housing 311. There are two rotors 313, one at each end of the stator 312, and fixedly connected to the rotating shaft 314. The shell 311 includes a cylindrical shell 311a, a proximal cover 311b and a distal cover 311c; wherein the proximal cover 311b is connected to the proximal end of the cylindrical shell 311a, and the distal cover 311c is connected to the distal end of the shell 311 to protect the rotor 313, the sensor 360 and the stator 312 to prevent blood from entering the interior of the shell 311.

[0077] See also Figure 9 、 Figure 13 and Figure 14 Optionally, at least one of the inner circumferential surface 314a of the rotating shaft 314 and the outer circumferential surface 34c of the fixed tube 340 is made of ceramic to reduce the friction coefficient between the rotating shaft 314 and the fixed tube 340 and reduce the friction force when the rotating shaft 314 and the fixed tube 340 rotate relative to each other.

[0078] See also Figure 9 、 Figure 13 and Figure 14 Optionally, a first gap 304 is formed between the inner circumference of the rotating shaft 314 and the outer circumference of the fixed tube 340. The first gap 304 connects the second flushing tube 420 and the lumen of the secondary sleeve 320. The secondary impeller 330 is provided with a through hole that axially penetrates the secondary impeller 330. The proximal portion of the through hole allows the rotating shaft 314 to be inserted and fixed, while the distal portion of the through hole allows the fixed tube 340 to pass through. A second gap is formed between the outer circumference of the fixed tube 340 and the inner circumference of the distal portion of the through hole. This second gap connects the first gap 304 with the lumen of the secondary sleeve 320.

[0079] This design allows the flushing fluid in the second flushing tube 420 to partially enter the first gap 304 and be discharged into the lumen of the secondary sleeve 320 through the second gap. This lubricates the inner circumference of the rotating shaft 314 and the outer circumference of the fixed tube 340, reducing the friction coefficient between the rotating shaft 314 and the fixed tube 340, and reducing the friction force during relative rotation of the rotating shaft 314 and the fixed tube 340. Furthermore, it removes heat generated by friction, dissipating heat from the rotating shaft 314 and the fixed tube 340. It also prevents blood in the lumen of the secondary sleeve 320 from entering the secondary motor 310 through the exit hole of the secondary impeller 330. Furthermore, it also allows the rotating shaft 314 to be suspended relative to the fixed tube 340, reducing friction between the rotating shaft 314 and the fixed tube 340.

[0080] See also Figure 9 、 Figure 13 and Figure 15 In addition, in other embodiments, a magnetic ring 317 is provided between one of the inner circumferential surface 314a of the rotating shaft 314 and the outer circumferential surface 34c of the fixed tube 340, and a magnet 318 is provided between the other. The magnetic ring 317 and the magnet 318 repel each other, so that the inner circumferential surface 314a of the rotating shaft 314 is suspended relative to the outer circumferential surface 34c of the fixed tube 340. For example, the magnetic ring 317 can be embedded in one of the inner circumferential surface 314a of the rotating shaft 314 and the magnet 318 can be provided on the other. The magnetic ring 317 and the magnet 318 repel each other and generate a repulsive force, so that the rotating shaft 314 is suspended relative to the fixed tube 340, so that the two do not contact each other, thereby reducing friction between the rotating shaft 314 and the fixed tube 340 during rotation.

[0081] In some embodiments, unlike the above-described embodiments, the secondary motor 310 may not include a rotating shaft 314, i.e., the secondary motor 310 is a shaftless motor. Specifically, the secondary motor 310 includes a housing 311, a stator 312, and a rotor 313 mounted within the housing 311. The rotor 313 is connected to the secondary impeller 330, and the stator 312 is capable of generating a magnetic field that drives the rotor 313 to rotate. In other words, the rotor 313 of the secondary motor 310 is directly connected to the secondary impeller 330, i.e., the rotor 313 is disposed on the secondary impeller 330. The stator 312 of the secondary motor 310 drives the rotor 313 of the secondary impeller 330 to rotate, thereby causing the rotor 313 to drive the secondary impeller 330 to rotate about the fixed tube 340.

[0082] In other embodiments, the secondary pumping device 300 does not include the fixed tube 340, and instead directly forms a portion of the intermediate passage 303 by hollowing the interior of the rotating shaft 314. Specifically, the secondary pumping device 300 includes a secondary motor 310, a secondary sleeve 320, and a secondary impeller 330 disposed within the secondary sleeve 320. The secondary motor 310 includes a rotating shaft 314, one end of which is rotatably disposed within the interior of the secondary motor 310 and the other end of which passes through the secondary impeller 330 and is rotatably connected to the distal end of the secondary sleeve 320. The rotating shaft 314 is configured to drive the secondary impeller 330 in rotation, and the hollow interior of the rotating shaft 314 forms at least a portion of the intermediate passage 303. As the rotating shaft 314 drives the secondary impeller 330 in rotation, the intermediate passage 303 within the rotating shaft 314 can carry the irrigation fluid to the first irrigation pipe 220 within the first conduit 200.

[0083] See also Figure 6 and Figure 16 In some embodiments, the primary casing 120 connects the outlet pipe 150 and the inlet pipe 140. The secondary pumping device 300 includes a secondary casing 320, which has a second inlet 301 and a second outlet 302 (eg, Figure 6 The main pumping device 100 includes a casing assembly, the casing assembly includes a main casing 120, an outlet pipe 150 having a first outlet 102 and an inlet pipe 140 having a first inlet 101 (as shown); Figure 16 As shown in FIG, the outlet tube 150 is connected to the proximal end of the primary sleeve 120, and the inlet tube 140 is connected to the distal end of the primary sleeve 120. The primary sleeve 120 is an elastic tube; the secondary sleeve 320 is a rigid tube.

[0084] The above design allows the primary cannula 120 to have excellent elasticity, allowing it to fully deform and adapt to the shape of the blood vessel, thereby facilitating its entry into the ventricle. Furthermore, since the primary pumping device 100 is clamped within the valve of the aorta 20 when entering the ventricle, the elasticity of the primary cannula 120 can buffer the forces acting between the valve and the primary cannula 120, reducing the reaction force on the valve and preventing valve damage. Since the secondary pumping device 300 is entirely located within the artery, the secondary cannula 320 of the secondary pumping device 300 does not contact the valve 21. Therefore, the secondary cannula 320 can be configured as a rigid tube, that is, the secondary cannula 320 can be made of a metal material, making it less susceptible to compression and deformation, ensuring smooth blood flow.

[0085] In some embodiments, the primary pumping device 100 further includes a primary motor 110 and a primary impeller 130. The primary motor 110 connects the first conduit 200 and the outlet tube 150. The primary impeller 130 is disposed within the outlet tube 150 and is connected to the rotating shaft of the primary motor 110. Optionally, the power of the secondary motor 310 is less than or equal to that of the primary motor 110. This design allows the primary pumping device 100 to pump blood through the aortic arch 22 while preventing the secondary motor 310 from being overpowered, thus reducing its size and simplifying implantation.

[0086] The blood pump 10 provided by the above-described solution comprises a primary pumping device 100, a first catheter 200, a secondary pumping device 300, and a second catheter 400, which are sequentially connected and communicated with each other. This allows, when the blood pump 10 is in operation, intraventricular blood flows sequentially from the first inlet 101 and first outlet 102 of the primary pumping device 100 into the ascending portion 22 of the aorta 20, and then flows out from the second inlet 301 and second outlet 302 of the secondary pumping device 300 into the descending portion 23 of the aorta 20. The presence of the secondary pumping device 300 generates negative pressure at the aortic arch 22, accelerating the flow of blood from the ascending portion 22 of the aorta 20 to the descending portion 23 of the aorta 20, thereby increasing blood flow. Furthermore, while ensuring sufficient blood flow, the diameter of each pump (primary pumping device 100 and secondary pumping device 300) can be reduced, thereby simplifying implantation.

[0087] Furthermore, because the second inlet 301 of the blood pump 10 of the present application is disposed on the outer peripheral wall of the secondary pumping device 300, the second inlet 301 can have a larger inlet area, thereby facilitating the blood in the aorta 20 to enter the secondary pumping device 300 through the second inlet 301 and significantly reducing the collision of the blood with the housing 311 of the secondary pumping device 300. Furthermore, because the proximal end of the first catheter 200 of the blood pump 10 is connected to the distal end of the secondary pumping device 300, if the second inlet 301 of the secondary pumping device 300 is disposed at the distal end, the blood flow at the second inlet 301 can easily flush the connection between the first catheter 200 and the secondary pumping device 300, thereby easily causing the first catheter 200 to fall off. Therefore, the blood pump 10 of the present application sets the second inlet 301 on the outer wall of the secondary pumping device 300, which not only avoids interference with the first catheter 200, but also reduces the erosion of the blood flow at the second inlet 301 on the connection between the first catheter 200 and the secondary pumping device 300, thereby preventing the proximal end of the first catheter 200 from loosening.

[0088] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0089] The above-described embodiments merely represent several implementation methods of the present application. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that a person of ordinary skill in the art may make various modifications and improvements without departing from the spirit of the present application, and these modifications and improvements fall within the scope of protection of the present application. Therefore, the scope of protection of the present patent application shall be determined by the appended claims.

Claims

1. A blood pump, characterized in that: The blood pump comprises a primary pumping device, a first conduit, a secondary pumping device and a second conduit connected in sequence; wherein, The primary pumping device is provided with a first inlet and a first outlet; the secondary pumping device is provided with a second inlet and a second outlet, and the second inlet is provided on the outer peripheral wall of the secondary pumping device; The secondary pumping device includes a secondary motor, a fixed tube, a secondary sleeve, and a secondary impeller disposed in the secondary sleeve; one end of the fixed tube is fixed to the interior of the secondary motor, and the other end passes through the secondary impeller and is fixed to the secondary sleeve; the secondary motor includes a housing and a rotating shaft mounted on the housing, the rotating shaft is sleeved on the outer circumference of the fixed tube, the distal end of the rotating shaft passes through the housing to be connected and fixed to the secondary impeller, and the rotating shaft is rotatable relative to the fixed tube; The blood pump also has at least one of the following features: At least one of the inner circumferential surface of the rotating shaft and the outer circumferential surface of the fixed tube is made of ceramic; A first gap is formed between the inner circumference of the rotating shaft and the outer circumference of the fixed tube, and the first gap is capable of allowing the flushing liquid to pass through; A magnetic ring is provided on one of the inner circumference of the rotating shaft and an outer circumference of the fixed tube, and a magnet is provided on the other. The magnetic ring and the magnet repel each other so that the inner circumference of the rotating shaft is suspended relative to the outer circumference of the fixed tube.

2. The blood pump according to claim 1, wherein The distal end of the secondary pumping device is provided with a connecting end; the proximal end of the first conduit is provided with a first sleeve portion, which is sleeved on the outer peripheral surface of the connecting end and fixedly connected to the connecting end.

3. The blood pump according to claim 2, characterized in that The first sleeve portion is configured to be trumpet-shaped, and the inner diameter of the first sleeve portion is configured to gradually increase in the direction along the first conduit to the secondary pumping device; the connecting end includes a first diameter-reducing circumferential surface, and the first diameter-reducing circumferential surface is configured to imitate the shape of the inner circumferential surface of the first sleeve portion so as to be adaptively connected to the first sleeve portion.

4. The blood pump according to claim 2, characterized in that The proximal end of the first catheter is also provided with a fixed cover, which is sleeved on the outer periphery of the first sleeve connection portion. The fixed cover is provided with a reducing diameter opening and an expanding diameter opening, and the periphery of the expanding diameter opening is fixedly connected to the connecting end; the periphery of the reducing diameter opening is sleeved on the first catheter, and the minimum diameter of the reducing diameter opening is smaller than the minimum diameter of the first sleeve connection portion.

5. The blood pump according to claim 4, characterized in that The fixing cover is made of metal material, the periphery of the enlarged diameter opening of the fixing cover is welded to the connecting end, and the outer peripheral surface of the fixing cover and the outer peripheral surface of the connecting end are smoothly transitioned and docked.

6. The blood pump according to any one of claims 2 to 5, characterized in that The distal end of the second catheter is provided with a second sleeve portion, and the proximal end of the secondary pumping device is provided with a fixing pin for the second sleeve portion to be sleeved and fixed; the interior of the secondary pumping device is also provided with a fixing tube, one end of the fixing tube is inserted and fixed to the fixing pin, and the other end is inserted and fixed to the connecting end.

7. The blood pump according to any one of claims 1 to 5, characterized in that The primary pumping device includes a casing assembly, which includes a primary casing, an outlet pipe provided with the first outlet, and an inlet pipe provided with the first inlet, and the primary casing connects the outlet pipe and the inlet pipe; the secondary pumping device includes a secondary casing, and the secondary casing is provided with the second inlet and the second outlet; wherein the primary casing is an elastic tube; the secondary casing is a rigid tube.

8. The blood pump according to claim 7, characterized in that The second inlet is provided on the outer peripheral wall of the distal end of the secondary sleeve; the second inlet comprises a plurality of inlet holes, and the plurality of inlet holes are distributed at intervals along the circumference of the secondary sleeve.

9. The blood pump according to any one of claims 1 to 5, characterized in that A first flushing pipe is provided inside the first conduit to supply flushing liquid to the primary pumping device, and a second flushing pipe is provided inside the second conduit to supply flushing liquid to the secondary pumping device; The secondary pumping device is provided with an intermediate passage, which extends along the axial direction of the secondary pumping device and penetrates the secondary pumping device to connect the first flushing pipe and the second flushing pipe.

10. The blood pump according to claim 9, characterized in that The inner hollow of the rotating shaft forms at least a portion of the middle channel.

11. The blood pump according to claim 9, characterized in that The interior hollowness of the fixed pipe forms at least a portion of the intermediate channel; and the secondary impeller is rotatable around the fixed pipe.

12. The blood pump according to claim 11, characterized in that The secondary motor further comprises a stator and a rotor mounted in the housing; wherein the rotor is fixedly connected to the outer circumference of the rotating shaft, and the stator is capable of generating a magnetic field to drive the rotor to rotate; Alternatively, the rotor is connected to the secondary impeller, and the stator can generate a magnetic field to drive the rotor to rotate.

13. The blood pump according to claim 12, characterized in that A first gap is formed between the inner circumferential surface of the rotating shaft and the outer circumferential surface of the fixed tube, and the first gap communicates with the second flushing tube and the lumen of the secondary sleeve.

14. The blood pump according to claim 11, characterized in that The diameter D3 of the fixed tube is smaller than the outer diameter D1 of the first conduit; and / or, the outer diameter D1 of the first conduit is smaller than the outer diameter D2 of the second conduit; And / or, the outer diameter D2 of the second conduit is less than twice the outer diameter D1 of the first conduit.

15. The blood pump according to any one of claims 1 to 5, characterized in that The length of the first catheter is 180 mm to 300 mm to enable the secondary pumping device to be located in the descending portion of the aorta.

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