A hair growth Chinese medicine composition and preparation method thereof

By using a specific epiphysealial composition prepared by a specific proportion, the problem of scalp pathogenic stimulation caused by the existing Chinese medicine compositions caused by the existing Chinese medicine compositions has achieved a significant effect of improving hair volume and reducing hair loss traces. At the same time, the skin is reduced to the skin The side effects occur.

CN116747267BActive Publication Date: 2025-01-28CHENGDU LONGQUANYI DISTRICT FIRST PEOPLES HOSPITAL
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Patent Information

Application Number
CN202310940217.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-07-28
Publication Date
2025-01-28
Estimated Expiration
2043-07-28

AI Technical Summary

Technical Problem

Existing hair-growing Chinese medicine compositions are prone to cause pathological irritation of the scalp when applied externally, resulting in side effects such as rash, pustules, peeling, urticaria, itching, pain, etc.

Method used

The use of a new type of Chinese medicine composition, including astragalus, cinnamon, pipe -side leaves, softened Shouwu, osteoma, bone fragments, sinensis, red flowers, asarum, ginseng leaves, tomb heads, 玳玳 flowers, and taushu, and Pu Hua and Pu, and Flower and Pu, Flower and Flower and Flower and Flower Flower and Flower Flower and Poor Flowers Chinese medicines such as Shenmu are prepared into scalp treatment through specific proportion and preparation methods.

Benefits of technology

This composition can effectively reduce the stimulus effect on the scalp, reduce skin pathological symptoms such as rash, pustules, peeling, etc., significantly increase the amount of hair, reduce hair loss traces, control oil secretion, and have good hair and skin care effects.

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Abstract

The invention discloses a hair-growth Chinese medicine composition, comprising 500g-800g of astragalus, 300g-400g of cinnamon bark, 300g-500g of oriental arborvitae leaf, 300g-400g of processed polygonum multiflorum, 300g-450g of psoralea corylifolia, 200g-400g of drynaria, 150g-350g of angelica, 100g-250g of safflower, 120g-260g of asarum and the like. The hair-growth Chinese medicinal composition of the present invention comprises ingredients such as Polygonum multiflorum, Platycladus orientalis leaves, Psoralea corylifolia, Rhizoma Drynariae and the like. The various Chinese medicinal ingredients can cooperate with each other to invigorate qi, activate blood circulation and dredge meridians; can regulate the growth environment of hair, promote blood circulation in the head, repair damaged hair follicles and promote the growth of new hair; can achieve a good therapeutic effect on seborrheic alopecia; can reduce the irritation of hair-growth fluid to the scalp, and reduce the occurrence of skin pathological symptoms such as rashes, pustules, peeling, urticaria, itching and pain.
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Description

Technical Field

[0001] The invention relates to the technical field of hair growth and health care, and in particular to a hair growth Chinese medicine composition. Background Art

[0002] Hair loss refers to the phenomenon of hair falling out. Normally lost hair is in the catagen and telogen phases. Since the hair entering the catagen and the hair entering the new growth phase are constantly in a dynamic balance, the normal amount of hair can be maintained. Pathological hair loss refers to abnormal or excessive hair loss, and there are many reasons for it.

[0003] There are two treatment options for hair loss. The first method is hair transplantation, which is to transplant hair follicles from the scalp where hair still grows to the area where hair does not grow, that is, from the back of the head to the front. The second method is local application of medication, which can effectively prevent continued hair loss caused by various reasons and promote hair regeneration in areas where hair is already bald or thin. Seborrheic alopecia often occurs in young and middle-aged people. It manifests as thicker oily secretions on the scalp, shiny hair, sparse and thin, or dry hair, more dandruff, dull, sparse and thin.

[0004] In the treatment of hair loss, Chinese medicine or Chinese medicine combination is often used for treatment or auxiliary treatment. For example, "Qianjin Fang" discloses: mulberry leaves, hemp leaves, each gram. Boil the medicine with rice wine water for 100 times, and take the water to bathe the hair. The formula of Polygonum multiflorum for treating hair loss is: Polygonum multiflorum, raw cypress, black sesame, Eclipta prostrata, Ligustrum lucidum, raw earth, each gram, tangerine peel, Sichuan pepper, and Daqing salt. Add milliliters of water, boil until milliliters, take the juice, put in black beans, and boil until the juice is completely absorbed by the beans. After drying the beans, chew and take 100 grams each time, 100 times a day, and stop when cured. The formula of Gastrodia elata for treating hair loss: Gastrodia elata, Polygonum multiflorum, cooked earth, white peony, angelica, papaya, Cuscuta australis, Chuanxiong. Grind them into powder, mix them into honey pills, each pill is grams. Take the pills in the morning and evening, with warm water.

[0005] For example, CN202111194150.7 discloses a drug for preventing hair loss and hair growth and a preparation method thereof. The specific preparation formula of the drug for preventing hair loss and hair growth includes: 2-3 parts of Polygonum multiflorum, 3-4 parts of wolfberry, 2-3 parts of mulberry, 1-2 parts of Angelica sinensis, 4-6 parts of Salvia miltiorrhiza, 2-4 parts of Chrysanthemum indica, 3-5 parts of Astragalus, 3-5 parts of Eclipta prostrata, 1-3 parts of Rehmannia root, 4-6 parts of dried ginger, 2-3 parts of Gleditsia sinensis, 3-4 parts of Deer antler, 3-5 parts of black sesame, 1-3 parts of walnut and 3-5 parts of straw ash liquid. More effective drugs can be prepared to treat hair loss and hair growth. When washing hair, the drug can be directly mixed with water to wash the hair without being taken into the human body, thereby reducing side effects on the human body and avoiding effects on the human body.

[0006] For example, CN201010156147.1 discloses an anti-hair loss agent, which is composed of the following substances: quinine sulfate: 2-4, linalool: 5-10, phenylethyl alcohol: 4-6, cinnamyl alcohol: 1-3, geraniol: 3-6, glycerin: 30-40, rose oil: 30-40, eugenol: 10-20, ethanol: 2300-2500, and distilled water: 80-100. The present invention has good effects: it can significantly control hair loss, promote the metabolic cycle of hair, enhance the vitality of hair, supplement nutrition, restore the growth rate of hair, strengthen hair roots, and can penetrate into hair follicles to remove grease, inhibit sebaceous glands, and let hair grow again. It feels cool when used; it has good therapeutic effects on seborrheic alopecia, alopecia areata, mixed alopecia, postpartum alopecia, etc.

[0007] It can be known from the prior art that hair growth-related pharmaceutical preparations include oral and topical preparations. Oral preparations are mainly for regulating qi and blood, while topical preparations are more effective for direct effects on scalp hair follicles, thereby achieving better hair growth and hair loss prevention effects. Statistics from the prior art show that most hair growth Chinese medicine compositions include Polygonum multiflorum, Astragalus, Dried Ginger, Angelica, Cinnamon, Platycladus orientalis, Psoralea corylifolia, Drynaria fortunei, etc.; different Chinese medicine compositions have different therapeutic effects.

[0008] However, the above-mentioned Chinese medicine composition has certain side effects, especially when applied externally. For example, astragalus may cause allergic reactions, such as rashes, urticaria, etc.; cinnamon powder can irritate the skin, causing skin itching, rashes, etc.; washing hair with Platycladus orientalis leaves may cause local itching and pain in the scalp tissue, and there will also be peeling. Some patients will experience symptoms of poisoning after use, such as dizziness, headache, etc., and may also be accompanied by numbness of the limbs, and there will also be difficulty breathing and shock. After contact with psoralea corylifolia, contact dermatitis may occur, such as changes in skin color, accompanied by itching, especially after being exposed to sunlight, sun-like damage occurs, and local skin can feel a burning sensation, and the pain is obvious, also known as phototoxic dermatitis. Angelica can achieve a whitening effect, but frequent or long-term use will cause redness, swelling, and pain in the skin, and may even cause local papules. Severe patients will also experience a local burning sensation.

[0009] In addition, some chemicals are usually added to hair growth liquid, such as ethanol, dipotassium glycyrrhizinate, minoxidil and other ingredients. These ingredients are somewhat irritating. Hair follicles are relatively fragile, and long-term use may also damage the hair follicles, causing rashes, pustules and pain symptoms.

[0010] Therefore, the Chinese medicine compositions in the prior art are more concerned with the anti-hair loss effect or hair growth effect, and pay less attention to the side effects such as pathological scalp irritation, rash, pustules, skin pain, etc.; these symptoms generally disappear automatically after drug withdrawal, but because hair growth is a long process, the patient's scalp may be in a pathological state for a long time during the treatment of hair loss. Summary of the invention

[0011] The purpose of the present invention is to provide a hair growth promoting Chinese medicinal composition and a preparation method thereof.

[0012] One of the purposes of the present invention is:

[0013] How to reduce the pathological stimulation of the scalp by the anti-hair loss and hair growth Chinese medicine composition preparation in the prior art, and reduce the occurrence of skin pathological symptoms such as scalp redness, rash, pustules, etc.

[0014] To achieve the above object, one embodiment of the present invention provides a hair growth promoting Chinese medicine composition, comprising the following Chinese medicines in a weight ratio:

[0015] Astragalus 500g~800g; Cinnamon 300g~400g; Platycladus orientalis leaves 300g~500g;

[0016] 300g~400g of processed Polygonum multiflorum; 300g~450g of Psoralea corylifolia; 200g~400g of Drynaria fortunei;

[0017] Angelica 150g~350g; Safflower 100g~250g; Asarum 120g~260g;

[0018] Ginseng leaves 130g~220g; Mutouhui 100g~200g; Daidai flower 100g~200g;

[0019] 50g to 100g of Poria cocos.

[0020] In the optimized embodiment of the present invention, the following Chinese medicines are included in the weight ratio:

[0021] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g;

[0022] 360g processed Polygonum multiflorum; 360g Psoralea corylifolia; 360g Drynaria fortunei;

[0023] Angelica 180g; Safflower 180g; Asarum 180g;

[0024] 180g ginseng leaves; 120g mutouhui; 130g daidai flower;

[0025] 60g of Poria cocos.

[0026] In the optimized embodiment of the present invention, the following Chinese medicines are included in the weight ratio:

[0027] Astragalus 550g; Cinnamon 320g; Platycladus orientalis leaves 300g;

[0028] 310g of processed Polygonum multiflorum; 360g of Psoralea corylifolia; 260g of Drynaria fortunei;

[0029] Angelica 220g; Safflower 180g; Asarum 230g;

[0030] 160g ginseng leaves; 140g mutouhui; 150g daidai flower;

[0031] 50g of Poria cocos.

[0032] Based on the above-mentioned Chinese medicine composition, the present invention discloses a method for preparing the hair-growth Chinese medicine composition, comprising the following steps:

[0033] (1) The following Chinese medicines are used as raw materials in a weight ratio:

[0034] Astragalus 500g~800g; Cinnamon 300g~400g; Platycladus orientalis leaves 300g~500g;

[0035] 300g~400g of processed Polygonum multiflorum; 300g~450g of Psoralea corylifolia; 200g~400g of Drynaria fortunei;

[0036] Angelica 150g~350g; Safflower 100g~250g; Asarum 120g~260g;

[0037] Ginseng leaves 130g~220g; Mutouhui 100g~200g; Daidai flower 100g~200g;

[0038] 50g-100g of Poria cocos;

[0039] (2) The above raw materials are prepared into a hair growth tincture, and the preparation method of the hair growth tincture is as follows:

[0040] Various Chinese medicines are crushed into coarse powder or sliced, immersed in 40% to 50% ethanol solution by mass, stirred and sealed, and immersed for 2d to 4d; the filtrate is obtained after filtering, and the filter residue is poured into water for decoction; after decoction, it is filtered and the filtrate is combined; then it is boiled for 5min to 10min, and finely filtered after cooling; after fine filtration, 3% to 5% glycerol by mass of the filtrate is added, stirred evenly, and filtered to obtain the hair growth tincture.

[0041] In the optimized embodiment of the present invention, the raw materials in the preparation method include:

[0042] Astragalus 550g; Cinnamon 320g; Platycladus orientalis leaves 300g;

[0043] 310g of processed Polygonum multiflorum; 360g of Psoralea corylifolia; 260g of Drynaria fortunei;

[0044] Angelica 220g; Safflower 180g; Asarum 230g;

[0045] 160g ginseng leaves; 140g mutouhui; 150g daidai flower;

[0046] 50g of Poria cocos.

[0047] In summary, the present invention has the following advantages:

[0048] 1. The hair-growth Chinese medicine composition of the present invention includes ingredients such as Polygonum multiflorum, Platycladus orientalis leaves, Psoralea corylifolia, and Drynaria fortunei. The various Chinese medicine ingredients can cooperate with each other to invigorate qi and activate blood circulation, and dredge meridians; can regulate the growth environment of hair, promote blood circulation in the head, repair damaged hair follicles, and promote new hair growth; and can achieve a good therapeutic effect on seborrheic alopecia.

[0049] 2. The composition of the present invention can reduce the irritation of hair growth liquid to the scalp and reduce the occurrence of skin pathological symptoms such as rash, pustules, peeling, urticaria, itching, pain, etc. DETAILED DESCRIPTION

[0050] The present invention provides a hair growth promoting Chinese medicine composition, comprising the following Chinese medicines in a weight ratio:

[0051] Astragalus 500g~800g; Cinnamon 300g~400g; Platycladus orientalis leaves 300g~500g;

[0052] 300g~400g of processed Polygonum multiflorum; 300g~450g of Psoralea corylifolia; 200g~400g of Drynaria fortunei;

[0053] Angelica 150g~350g; Safflower 100g~250g; Asarum 120g~260g;

[0054] Ginseng leaves 130g~220g; Mutouhui 100g~200g; Daidai flower 100g~200g;

[0055] 50g to 100g of Poria cocos.

[0056] In one embodiment of the present invention, the hair growth promoting Chinese medicine composition comprises the following Chinese medicines in a weight ratio:

[0057] Astragalus 550g; Cinnamon 320g; Platycladus orientalis leaves 300g;

[0058] 310g of processed Polygonum multiflorum; 360g of Psoralea corylifolia; 260g of Drynaria fortunei;

[0059] Angelica 220g; Safflower 180g; Asarum 230g;

[0060] 160g ginseng leaves; 140g mutouhui; 150g daidai flower;

[0061] 50g of Poria cocos.

[0062] The present invention discloses a method for preparing a hair-growth-promoting Chinese medicine composition, comprising the following steps:

[0063] (1) The following Chinese medicines are used as raw materials in a weight ratio:

[0064] Astragalus 500g~800g; Cinnamon 300g~400g; Platycladus orientalis leaves 300g~500g;

[0065] 300g~400g of processed Polygonum multiflorum; 300g~450g of Psoralea corylifolia; 200g~400g of Drynaria fortunei;

[0066] Angelica 150g~350g; Safflower 100g~250g; Asarum 120g~260g;

[0067] Ginseng leaves 130g~220g; Mutouhui 100g~200g; Daidai flower 100g~200g;

[0068] 50g-100g of Poria cocos;

[0069] (2) The above raw materials are prepared into a hair growth tincture, and the preparation method of the hair growth tincture is as follows:

[0070] Various Chinese medicines are crushed into coarse powder or sliced, immersed in 40% to 50% ethanol solution by mass, stirred and sealed, and immersed for 2d to 4d; the filtrate is obtained after filtering, and the filter residue is poured into water for decoction; after decoction, it is filtered and the filtrate is combined; then it is boiled for 5min to 10min, and finely filtered after cooling; after fine filtration, 3% to 5% glycerol by mass of the filtrate is added, stirred evenly, and filtered to obtain the hair growth tincture.

[0071] The present invention adds a variety of traditional Chinese medicine components, which are obtained according to the principle of mutual synergistic compatibility of traditional Chinese medicines. The ratio of the traditional Chinese medicine components can be appropriately adjusted according to actual conditions and applicable populations.

[0072] Astragalus: It has the effects of strengthening the spleen and replenishing the middle, raising yang and lifting the sunken, strengthening the body's defense and strengthening the exterior, promoting urination, and removing toxins and promoting tissue regeneration. It is mainly used to treat spleen qi deficiency syndrome, lung qi deficiency syndrome, qi deficiency and spontaneous sweating syndrome, qi and blood deficiency, sores that are difficult to heal or ulcers that are difficult to heal, or sores that are difficult to heal for a long time.

[0073] Cinnamon; it has the effects of warming the middle and tonifying the kidney, dispelling cold and relieving pain. It is mainly used to treat cold pain in the waist and knees, stomach pain due to deficiency and cold, chronic indigestion, abdominal pain, vomiting and diarrhea, amenorrhea caused by cold and other diseases.

[0074] Platycladus orientalis leaves; bitter, slightly cold, clearing, astringent, sticky, astringent, enters the lung, liver, spleen, and large intestine meridians. It cools the blood, astringes and stops bleeding, and is an important medicine for treating internal and external bleeding. It should be used raw for those with blood heat, and fried for those with cold deficiency. It can also clear the lungs, resolve phlegm and stop coughing, and can be used to treat lung heat, cough, asthma and excessive phlegm. It can also clear heat, cool blood and promote hair growth and black hair, and can be used to treat hair loss and premature graying of hair due to blood heat. This product mainly contains flavonoids, such as quercetin, quercetin, kaempferol, etc.; contains volatile oils, such as cedarwood, acetic acid pine oil, and tannins. It has the effects of cooling blood and stopping bleeding, resolving phlegm and relieving cough, and promoting hair growth and black hair.

[0075] Polygonum multiflorum; enters the liver and kidney meridians, and has different properties and effects when used in processed and raw forms. When used in processed form, it is slightly warm, sweet and astringent, not greasy or dry, good at nourishing the liver and kidney, benefiting the essence and blood, and blackening the hair. It is a good tonic medicine and is good at treating the deficiency of essence and blood. When used in raw form, it is flat and slightly cool, more bitter than sweet, good at purging but weak in tonifying deficiency, can detoxify, stop malaria, moisten the intestines, and treat sores, scrofula, long-term malaria due to physical weakness, and constipation due to dry intestines. This product contains anthraquinone compounds, the main components of which are chrysophanol and rhubarb, as well as lecithin, crude fat, etc. It has the functions of detoxification, eliminating carbuncle, stopping malaria, and moistening the intestines.

[0076] Psoralea corylifolia; bitter, pungent, warm and dry, warming and astringent, enters the kidney and spleen meridians. It can nourish the kidney and strengthen yang, consolidate essence and reduce urine, and promote qi and relieve asthma. It can treat impotence due to kidney deficiency, spermatorrhea, and asthma due to kidney deficiency; it can also warm the spleen and stop diarrhea, and is an important medicine for diarrhea due to spleen and kidney yang deficiency. It is known as "broken old paper", which is the homophone of its correct name. This product contains coumarins such as psoralen and isopsoralen, flavonoids such as astragaloside, and monoterpene phenols such as bakuchiol. It also contains ingredients such as stigmasterol, sitosterol, glucoside, and raffinose. It has the effects of nourishing the kidney and strengthening yang, consolidating essence and reducing urine, warming the spleen and stopping diarrhea, and promoting qi and relieving asthma.

[0077] Drynaria fortunei: bitter and warm in nature. Enters the liver and kidney meridians. Mainly contains naringin, methyl eugenol, drynaria fortunei dihydroflavonoid glycosides, drynaria acid, sitosterol, protocatechuic acid and other ingredients. It has the effects of healing wounds and relieving pain, strengthening the kidney and strengthening bones; external use can eliminate wind and remove spots.

[0078] Angelica sinensis: sweet and nourishing, pungent and warm, dispersing, mainly enters the liver and heart meridians, and also enters the spleen meridian. It is good at nourishing blood and activating blood circulation, regulating menstruation and relieving pain, moistening the intestines and relieving constipation, and can dispel cold. It is suitable for all symptoms of blood deficiency, blood stasis and cold, especially for those with dry intestines and constipation. It is not only an important medicine for regulating menstruation in gynecology, but also a good product for blood tonic in internal medicine. It is also commonly used for swelling and wound treatment in surgery and trauma. It mainly contains volatile oils such as ligustilide, angelica ketone, cinnamaldehyde, n-butyl furanolide, verbenone, safrole, organic acid components such as ferulic acid, vanillic acid, niacin, succinic acid, and angelica polysaccharides, amino acids, vitamin A and other ingredients.

[0079] Safflower: used for amenorrhea, dysmenorrhea, lochia retention, abdominal masses, chest pain, abdominal pain due to blood stasis, stabbing pain in the chest and flanks, injuries from falls, and sores and swelling.

[0080] Asarum; pungent and warm in nature. It enters the heart, lung and kidney meridians. Asarum has a strong aromatic smell, and is pungent and warm. It enters the heart, lung and kidney meridians, and penetrates the inside and outside. It is slightly toxic but has strong effects. It is good at dispelling wind and cold, opening the orifices and relieving pain. It is a good medicine for treating pain caused by wind and cold, rheumatism, and headache caused by sinusitis and nasal congestion. It can warm and dispel lung cold, and resolve phlegm and fluid. It is an important medicine for treating cold fluid in the lungs. It is most suitable for Shaoyin headache, sinusitis headache and toothache. This product contains lignin components, volatile oils, and trace amounts of aristolochic acid I. It has the effects of dispelling cold, dispelling wind and relieving pain, opening the orifices, warming the lungs and resolving fluid.

[0081] Ginseng leaf: bitter and sweet, cold in nature, enters the lung and stomach meridians. It mainly contains ginsenosides, kaempferol, ginseng flavonoids and other ingredients. It has the effects of replenishing qi, benefiting the lungs, dispelling heat and promoting body fluid. It is often used for cough due to qi deficiency, irritability due to summer heat, thirst due to loss of body fluid, unclear head and fatigue of limbs.

[0082] Mutouhui: It is the root of Patrinia corydalis or Patrinia heterophylla of the Patrinaceae family. It tastes bitter, slightly sour and astringent, and is cool in nature. It enters the heart and liver meridians. It has the effects of drying dampness and stopping leucorrhea, astringing and stopping bleeding, clearing away heat and detoxifying. It can treat leucorrhea, metrorrhagia, diarrhea, dysentery, jaundice, malaria, intestinal carbuncle, sore swelling, traumatic injury, cervical cancer, gastric cancer and other diseases.

[0083] Daidai flower; spicy, sweet, slightly bitter, neutral in nature. It has the effects of regulating qi and relieving chest tightness, harmonizing the stomach and stopping vomiting. It is often used for chest tightness, abdominal distension and pain, loss of appetite, nausea and vomiting.

[0084] Fushenmu, a Chinese medicine name. It is the pine root in the middle of the sclerotium of the Polyporaceae fungus Poria cocos (Schw.) Wolf. It has the effect of calming the liver and tranquilizing the mind. It is used for palpitations and forgetfulness, slurred speech due to stroke, and beriberi and cramps.

[0085] Embodiment 1:

[0086] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0087] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g;

[0088] 360g processed Polygonum multiflorum; 360g Psoralea corylifolia; 360g Drynaria fortunei;

[0089] Angelica 180g; Safflower 180g; Asarum 180g;

[0090] 180g of ginseng leaves; 120g of mulberry leaves; 130g of daidai flowers; 60g of poria wood.

[0091] The preparation method of the hair-growth-promoting Chinese medicine composition comprises the following steps:

[0092] (1) Prepare Chinese medicine raw materials according to the formula;

[0093] (2) Grind various Chinese medicines into coarse powder or slices, add 40% ethanol solution by mass to immerse, stir and seal, and immerse for 3 days; obtain the filtrate after filtering, and pour the filter residue into water for decoction, with the weight ratio of water to filter residue being 3:1. Filter after decoction and combine the filtrate; then boil for 6 minutes, cool and filter; after fine filtration, add 4% glycerol by mass of the filtrate, stir evenly and filter to obtain hair growth tincture.

[0094] Embodiment 2:

[0095] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0096] Astragalus 550g; Cinnamon 320g; Platycladus orientalis leaves 300g;

[0097] 310g of processed Polygonum multiflorum; 360g of Psoralea corylifolia; 260g of Drynaria fortunei;

[0098] Angelica 220g; Safflower 180g; Asarum 230g;

[0099] 160g of ginseng leaves; 140g of mutouhui; 150g of daidaihua; 50g of poria wood.

[0100] The preparation method of the hair-growth-promoting Chinese medicine composition comprises the following steps:

[0101] (1) Prepare Chinese medicine raw materials according to the formula;

[0102] (2) Grind various Chinese medicines into coarse powder or slices, add 40% ethanol solution by mass to immerse, stir and seal, and immerse for 3 days; obtain the filtrate after filtering, and pour the filter residue into water for decoction, with the weight ratio of water to filter residue being 3:1. Filter after decoction and combine the filtrate; then boil for 6 minutes, cool and filter; after fine filtration, add 4% glycerol by mass of the filtrate, stir evenly and filter to obtain hair growth tincture.

[0103] Embodiment 3:

[0104] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0105] Astragalus 520g; Cinnamon 310g; Platycladus orientalis leaves 320g;

[0106] 330g of processed Polygonum multiflorum; 350g of Psoralea corylifolia; 280g of Drynaria fortunei;

[0107] Angelica 230g; Safflower 160g; Asarum 220g;

[0108] 180g ginseng leaves; 150g mulberry leaf; 160g daidai flower; 60g poria wood.

[0109] The preparation method of the hair-growth-promoting Chinese medicine composition comprises the following steps:

[0110] (1) Prepare Chinese medicine raw materials according to the formula;

[0111] (2) Grind various Chinese medicines into coarse powder or slices, add 40% ethanol solution by mass to immerse, stir and seal, and immerse for 3 days; obtain the filtrate after filtering, and pour the filter residue into water for decoction, with the weight ratio of water to filter residue being 3:1. Filter after decoction and combine the filtrate; then boil for 5 minutes, cool and filter; after fine filtration, add 5% glycerol by mass of the filtrate, stir evenly and filter to obtain hair growth tincture.

[0112] Embodiment 4:

[0113] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0114] Astragalus 580g; Cinnamon 350g; Platycladus orientalis leaves 320g;

[0115] 260g of processed Polygonum multiflorum; 290g of Psoralea corylifolia; 230g of Drynaria fortunei;

[0116] Chinese Angelica 200g; Safflower 200g; Asarum 250g;

[0117] 180g of ginseng leaves; 120g of mulberry leaves; 160g of daidai flowers; 70g of poria wood.

[0118] The preparation method of the hair-growth-promoting Chinese medicine composition comprises the following steps:

[0119] (1) Prepare Chinese medicine raw materials according to the formula;

[0120] (2) Grind various Chinese medicines into coarse powder or slices, add 40% ethanol solution by mass to immerse, stir and seal, and immerse for 3 days; obtain the filtrate after filtering, and pour the filter residue into water for decoction, with the weight ratio of water to filter residue being 3:1. Filter after decoction and combine the filtrate; then boil for 6 minutes, cool and filter; after fine filtration, add 4% glycerol by mass of the filtrate, stir evenly and filter to obtain hair growth tincture.

[0121] Embodiment 5:

[0122] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0123] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 260g;

[0124] 280g of processed Polygonum multiflorum; 320g of Psoralea corylifolia; 230g of Drynaria fortunei;

[0125] Angelica 210g; Carthamus tinctorius 220g; Asarum 240g;

[0126] 180g of ginseng leaves; 160g of mutouhui; 160g of daidaihua; 90g of poria wood.

[0127] The preparation method of the hair-growth-promoting Chinese medicine composition comprises the following steps:

[0128] (1) Prepare Chinese medicine raw materials according to the formula;

[0129] (2) Grind various Chinese medicines into coarse powder or slices, add 40% ethanol solution by mass to immerse, stir and seal, and immerse for 3 days; obtain the filtrate after filtering, and pour the filter residue into water for decoction, with the weight ratio of water to filter residue being 3:1. Filter after decoction and combine the filtrate; then boil for 6 minutes, cool and filter; after fine filtration, add 4% glycerol by mass of the filtrate, stir evenly and filter to obtain hair growth tincture.

[0130] Experimental Example 1: Hair Growth Effect Experiment

[0131] (1) Experimental records of 90 patients, including 60 males and 30 females; the patients were between 35 and 50 years old with alopecia areata and sparse hair. All patients were divided into five groups, each with 30 people, 20 males and 10 females. The first group was treated with the drug of Example 1, the second group was treated with the drug of Example 2, and the third group was treated with the drug of Example 3.

[0132] (2) All patients should wash their hair before using the medicine, and then test their hair density after drying their hair; hair density is the total number of hair roots per square centimeter. Select an area with more severe hair loss in the area of ​​the patient's alopecia areata or hair loss as the marking area; mark the test site, and test the marked area or test site each time. The position of the marked area tested for each patient may be different, but the area of ​​the marked area of ​​each patient at each position is the same; the hair density of the patient can be obtained after each test is completed. The average hair density of each group is the ratio of the sum of the hair density values ​​of all patients in the group to the number of people, that is, the average hair density can be obtained.

[0133] (3) Each patient was smeared with the hair growth tincture of the present invention, twice a day, with about 10 ml of the hair growth tincture applied each time, and massaged for 3-5 minutes after application. The hair growth tincture was used continuously for 2 months, and the hair density after 2 months of use was tested. The average hair density before treatment and the average hair density after 2 months of treatment were calculated for each group or each corresponding embodiment. The hair density of the patient before applying the drug was used as a comparison to test the hair growth effect of the hair growth tincture of the present invention, and its specific hair growth effect is as follows.

[0134] Group Average hair density before treatment Average hair density after 2 months Example 1 76±6 103±10 Example 2 65±8 91±6 Example 3 87±12 122±12 Example 4 59±6 76±8

[0135] From the above, it can be known that the hair growth tincture of the present invention can significantly increase the amount of hair after being used for a period of time. From the on-site usage situation, after use, the traces of hair loss are reduced, the hair follicles are healthy, and the oil control effect is also relatively ideal.

[0136] Experimental Example 2: Effect of Hair Growth Tincture on Skin Care

[0137] (A1) Experimental records of 200 patients, aged 35 to 50 years old, with alopecia areata and sparse hair; all patients were divided into 5 groups, 40 in each group. Each group of patients was treated with the same medication, and the specific medications for each group are as follows:

[0138] Experimental Group A:

[0139] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0140] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g;

[0141] 360g processed Polygonum multiflorum; 360g Psoralea corylifolia; 360g Drynaria fortunei;

[0142] Angelica 180g; Safflower 180g; Asarum 180g;

[0143] 180g of ginseng leaves; 120g of mulberry leaves; 130g of daidai flowers; 60g of poria wood.

[0144] The preparation method of the hair-growth-promoting Chinese medicine composition comprises the following steps:

[0145] (1) Prepare Chinese medicine raw materials according to the formula;

[0146] (2) Grind various Chinese medicines into coarse powder or slices, add 40% ethanol solution by mass to immerse, stir and seal, and immerse for 3 days; obtain the filtrate after filtering, and pour the filter residue into water for decoction, with the weight ratio of water to filter residue being 3:1. Filter after decoction and combine the filtrate; then boil for 6 minutes, cool and filter; after fine filtration, add 4% glycerol by mass of the filtrate, stir evenly and filter to obtain hair growth tincture.

[0147] That is, the first group adopted the Chinese medicine composition of Example 1.

[0148] Control group 1:

[0149] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0150] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g;

[0151] 360g processed Polygonum multiflorum; 360g Psoralea corylifolia; 360g Drynaria fortunei;

[0152] 180g of Angelica sinensis; 180g of safflower; 180g of asarum; 180g of ginseng leaf.

[0153] Compared with the first group, 120g of Mutouhui, 130g of Daidaihua and 60g of Fushenmu were reduced.

[0154] Control group 2:

[0155] The hair growth Chinese medicine composition includes the following Chinese medicines in weight ratio:

[0156] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g;

[0157] 360g processed Polygonum multiflorum; 360g Psoralea corylifolia; 360g Drynaria fortunei;

[0158] 180g of Angelica sinensis; 180g of safflower; 180g of asarum; 180g of ginseng leaf; 60g of Poria cocos.

[0159] Compared with the first group, the amount of tomb return was reduced by 120g and the amount of Dai Dai Hua was reduced by 130g.

[0160] Control group 3

[0161] Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g; Processed Polygonum multiflorum 360g; Psoralea corylifolia 360g;

[0162] Drynaria fortunei 360g; Chinese angelica 180g; Carthamus tinctorius 180g; Asarum 180g;

[0163] 180g ginseng leaves; 50g salvia miltiorrhiza, 50g camellia seeds.

[0164] Compared with the first group, the amount of Mutouhui, Daidaihua and Fushenmu was reduced by 120g; and the amount of Salvia miltiorrhiza and Camellia oleifera were increased by 50g.

[0165] Control group 4:

[0166] Quinine sulfate: 2-4, linalool: 5-10, phenylethyl alcohol: 4-6, cinnamyl alcohol: 1-3, geraniol: 3-6, glycerol: 30-40, rose oil: 30-40, eugenol: 10-20, ethanol: 2300-2500, distilled water: 80-100. Control group 4 is a chemical type of hair growth liquid.

[0167] (A2) Each patient was given a hair growth product twice a day, and massaged for 5 minutes after each application. After 2 weeks of continuous use, the patient's head skin was checked for pathological symptoms, including redness, swelling, rash, pustules, pain, peeling, etc. The number of patients with pathological symptoms in each group was recorded.

[0168] (A3) Test results of the patients’ scalp after using the hair growth products in each group

[0169] Group Mild symptoms Moderate symptoms Severe symptoms Total symptoms Asymptomatic Experimental Group A 2 1 0 3 37 Control group 1 5 3 1 9 31 Control group 2 7 4 0 11 29 Control group 3 6 3 1 10 30 Control group 4 11 5 2 18 22

[0170] From the above experiments, it can be seen that the number of asymptomatic patients of the hair growth tincture in the experimental group A of the present invention is the largest, and the number of asymptomatic patients in the control group 4 is the smallest, indicating that the pharmaceutical composition corresponding to Example 1 of the present invention has the smallest irritation to the skin, has a milder use experience, is not likely to cause pathological problems of the skin, and reduces the side effects of the scalp after using the drug. The product of the present invention has good long-term safety, that is, it will not have adverse effects on the human scalp under long-term use.

Claims

1. A hair growth promoting Chinese medicine composition, which is made from the following Chinese medicine raw materials in the following weight ratios: Astragalus 500g~800g; Cinnamon 300g~400g; Platycladus orientalis leaves 300g~500g; 300g~400g of processed Polygonum multiflorum; 300g~450g of Psoralea corylifolia; 200g~400g of Drynaria fortunei; Angelica 150g~350g; Safflower 100g~250g; Asarum 120g~260g; Ginseng leaves 130g~220g; Mutouhui 100g~200g; Daidai flower 100g~200g; 50g to 100g of Poria cocos.

2. The hair-growth-promoting Chinese medicinal composition according to claim 1, characterized in that: Made from the following Chinese medicinal materials in the following weight ratios: Astragalus 600g; Cinnamon 360g; Platycladus orientalis leaves 360g; 360g processed Polygonum multiflorum; 360g Psoralea corylifolia; 360g Drynaria fortunei; Angelica 180g; Safflower 180g; Asarum 180g; 180g ginseng leaves; 120g mutouhui; 130g daidai flower; 60g of Poria cocos.

3. The hair-growth-promoting Chinese medicinal composition according to claim 1, characterized in that: Made from the following Chinese medicinal materials in the following weight ratios: Astragalus 550g; Cinnamon 320g; Platycladus orientalis leaves 300g; 310g of processed Polygonum multiflorum; 360g of Psoralea corylifolia; 260g of Drynaria fortunei; Angelica 220g; Safflower 180g; Asarum 230g; 160g ginseng leaves; 140g mutouhui; 150g daidai flower; 50g of Poria cocos.

4. A method for preparing a hair-growth-promoting Chinese medicine composition, characterized in that: The following steps are involved: (1) The following Chinese medicines are used as raw materials in a weight ratio: Astragalus 500g~800g; Cinnamon 300g~400g; Platycladus orientalis leaves 300g~500g; 300g~400g of processed Polygonum multiflorum; 300g~450g of Psoralea corylifolia; 200g~400g of Drynaria fortunei; Angelica 150g~350g; Safflower 100g~250g; Asarum 120g~260g; Ginseng leaves 130g~220g; Mutouhui 100g~200g; Daidai flower 100g~200g; 50g-100g of Poria cocos; (2) The above raw materials are prepared into a hair growth tincture, and the preparation method of the hair growth tincture is as follows: Various Chinese medicines are crushed into coarse powder or sliced, immersed in 40% to 50% ethanol solution by mass, stirred and sealed, and immersed for 2d to 4d; the filtrate is obtained after filtering, and the filter residue is poured into water for decoction; after decoction, it is filtered and the filtrate is combined; then it is boiled for 5min to 10min, and finely filtered after cooling; after fine filtration, 3% to 5% glycerol by mass of the filtrate is added, stirred evenly, and filtered to obtain the hair growth tincture.

5. The preparation method according to claim 4, characterized in that: The Chinese medicine raw materials are: Astragalus 550g; Cinnamon 320g; Platycladus orientalis leaves 300g; 310g of processed Polygonum multiflorum; 360g of Psoralea corylifolia; 260g of Drynaria fortunei; Angelica 220g; Safflower 180g; Asarum 230g; 160g ginseng leaves; 140g mutouhui; 150g daidai flower; 50g of Poria cocos.

Citation Information

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