A sterilization control method, system, sterilizer and medium for pharmaceutical packaging materials

Abstract

The present invention discloses a sterilization control method, system, sterilizer and medium for pharmaceutical packaging materials, and relates to the field of sterilization control. It judges whether the temperature of an inner chamber reaches a preset temperature. If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the heating rate and the current heating power of the current heating device are determined according to the operation information. It is judged based on the heating rate whether the heating power needs to be adjusted. If the heating power needs to be adjusted, the heating power is adjusted to the preset power, thereby realizing accurate control of the temperature rise during the sterilization process according to the information of the sterilizer in operation, and improving the safety of the sterilization process.

Description

Technical Field

[0001] The present invention relates to the field of sterilization control, and in particular to a sterilization control method, system, sterilizer and medium for pharmaceutical packaging materials. Background Art

[0002] As the requirements for pharmaceutical packaging materials become increasingly stringent, the inspection and requirements for pharmaceutical packaging materials are also getting higher and higher. The sterilization requirements for pharmaceutical packaging materials are very different from those for ordinary equipment and items. Before testing pharmaceutical packaging materials, they must first be sterilized with high-temperature steam. There are strict requirements for the heating and cooling processes. There are few sterilization equipment on the market for this pharmaceutical packaging material process, and most users use ordinary equipment for processing.

[0003] In the prior art, most sterilizers on the market can only kill microorganisms and achieve a predetermined sterilization effect, but cannot effectively and accurately control the temperature rise process. Summary of the invention

[0004] The purpose of the present invention is to provide a sterilization control method, system, sterilizer and medium for pharmaceutical packaging materials, by judging whether the temperature of the inner chamber reaches the preset temperature. If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the heating rate and the current heating power of the current heating device are determined according to the operation information. Based on the heating rate, it is judged whether the heating power needs to be adjusted. If the heating power needs to be adjusted, the heating power is adjusted to the preset power, thereby realizing accurate control of the temperature rise during the sterilization process according to the information of the sterilizer in operation, and improving the safety of the sterilization process.

[0005] In order to solve the above technical problems, the present invention provides a sterilization control method for pharmaceutical packaging materials, which is applied to a sterilizer, wherein the sterilizer comprises: a heating device arranged in an inner chamber of the sterilizer, a cooling device arranged in the inner chamber of the sterilizer, and a control module arranged in the inner chamber of the sterilizer, wherein the control module is connected to the heating device and the cooling device respectively; the method comprises:

[0006] Determining whether the temperature of the inner chamber reaches a preset temperature;

[0007] If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the current heating rate and the current heating power of the heating device are determined according to the operation information;

[0008] Determining whether the heating power needs to be adjusted based on the heating rate;

[0009] If the heating power needs to be adjusted, the heating power is adjusted to a preset power.

[0010] Preferably, judging whether the heating power needs to be adjusted based on the temperature of the sterilizer after the first preset time, and if the heating power needs to be adjusted, adjusting the heating power to a preset power comprises:

[0011] controlling the heating device to heat at the heating rate for a first preset time, and calculating the temperature of the sterilizer after the first preset time;

[0012] determining a first temperature difference between the preset temperature and the temperature of the sterilizer after the first preset time has elapsed;

[0013] determining a current percentage between the first temperature difference and a target first temperature difference;

[0014] If the current percentage is less than the first preset percentage, adjusting the heating power to the first preset power;

[0015] If the current percentage is not less than the first preset percentage and greater than the second preset percentage, the heating power is adjusted to the second preset power; wherein the second preset power is less than the first preset power.

[0016] Preferably, calculating the temperature of the sterilizer after the first preset time has passed comprises:

[0017] Calculating the product of the first preset time and the heating rate to obtain a temperature change value;

[0018] The temperature change value and the preset temperature are summed to obtain the temperature of the sterilizer after the first preset time has passed.

[0019] Preferably, before controlling the heating device to heat at the heating rate for a first preset time, the method further comprises:

[0020] Determining the magnitude relationship between the heating rate and a preset rate;

[0021] If the heating rate is equal to the preset rate, triggering the step of controlling the heating device to heat at the heating rate for a first preset time;

[0022] If the heating rate is greater than the preset rate, controlling the heating device to stop heating;

[0023] If the heating rate is less than the preset rate, the heating device is controlled to heat at the heating rate for a second preset time, and the second preset time is greater than the first preset time.

[0024] Preferably, after controlling the heating device to heat at the heating rate for a first preset time, the method further comprises:

[0025] Determining the magnitude relationship between the current temperature of the inner chamber and the target temperature;

[0026] If the current temperature of the inner chamber is greater than or equal to the target temperature, determining whether the pressure of the inner chamber is less than a preset pressure value;

[0027] If the pressure of the inner chamber is lower than the preset pressure value, controlling the cooling device to cool down;

[0028] If the current temperature of the inner chamber is lower than the target temperature, the heating device is controlled to heat at the heating rate for the first preset time, and the process jumps again to the step of determining the magnitude relationship between the current temperature of the inner chamber and the target temperature.

[0029] Preferably, controlling the cooling device to cool down comprises:

[0030] Controlling the cooling device to cool down the first preset time at a target cooling rate, and calculating the temperature of the sterilizer after cooling, wherein the target cooling rate is equal to the heating rate;

[0031] Determining a second temperature difference between the current temperature of the inner chamber and the temperature of the sterilizer after the temperature is reduced;

[0032] determining a current percentage between the second temperature difference and a target second temperature difference;

[0033] If the current percentage is less than the first preset percentage, adjusting the cooling power to the first preset power;

[0034] If the current percentage is not less than the first preset percentage and greater than the second preset percentage, the cooling power is adjusted to the second preset power.

[0035] Preferably, after controlling the cooling device to cool down at the target cooling rate for the first preset time, the method further includes:

[0036] Determining the magnitude relationship between the current temperature of the inner chamber and the preset temperature;

[0037] If the current temperature of the inner chamber is less than or equal to the preset temperature, controlling the cooling device to stop cooling;

[0038] If the current temperature of the inner chamber is greater than the preset temperature, the cooling device is controlled to cool at the target cooling rate for the first preset time, and the process jumps again to the step of determining the magnitude relationship between the current temperature of the inner chamber and the preset temperature.

[0039] In order to solve the above technical problems, the present invention also provides a sterilization control system for pharmaceutical packaging materials, which is applied to a sterilizer, wherein the sterilizer comprises: a heating device arranged in an inner chamber of the sterilizer, a cooling device arranged in an inner chamber of the sterilizer, and a control module arranged in the inner chamber of the sterilizer, wherein the control module is connected to the heating device and the cooling device respectively; the system comprises:

[0040] a first judging unit, configured to judge whether the temperature of the inner chamber reaches a preset temperature, and if so, trigger the determining unit;

[0041] The determining unit is used to determine the current operation information of the sterilizer, and determine the current heating rate and the current heating power of the heating device according to the operation information;

[0042] a second judging unit, configured to judge whether the heating power needs to be adjusted based on the heating rate, and if so, trigger an adjusting unit;

[0043] The adjustment unit is used to adjust the heating power to a preset power.

[0044] In order to solve the above technical problems, the present invention also provides a sterilizer, comprising:

[0045] A heating device disposed in the sterilizer chamber;

[0046] A cooling device provided in the sterilizer chamber;

[0047] A control module is arranged in the inner chamber of the sterilizer, and the control module is connected to the heating device and the cooling device respectively, and is used to implement the steps of the sterilization control method of the pharmaceutical packaging material as described above when executing the computer program.

[0048] In order to solve the above technical problems, the present invention also provides a computer-readable storage medium, on which a computer program is stored. When the computer program is executed by a processor, the steps of the sterilization control method for pharmaceutical packaging materials as described above are implemented.

[0049] The purpose of the present invention is to provide a sterilization control method, system, sterilizer and medium for pharmaceutical packaging materials, by judging whether the temperature of the inner chamber reaches the preset temperature. If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the heating rate and the current heating power of the current heating device are determined according to the operation information. Based on the heating rate, it is judged whether the heating power needs to be adjusted. If the heating power needs to be adjusted, the heating power is adjusted to the preset power, thereby realizing accurate control of the temperature rise during the sterilization process according to the information of the sterilizer in operation, and improving the safety of the sterilization process. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the prior art and the drawings required for use in the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0051] Figure 1 A process flow chart of a sterilization control method for pharmaceutical packaging materials provided by the present invention;

[0052] Figure 2 A schematic diagram of a process control provided by the present invention;

[0053] Figure 3 A curve diagram of uniform heating and uniform cooling provided by the present invention;

[0054] Figure 4 A curve diagram of rapid heating and rapid cooling provided by the present invention;

[0055] Figure 5 A schematic diagram of the structure of a sterilizer provided by the present invention;

[0056] Figure 6 A schematic diagram of the structure of a system provided by the present invention;

[0057] Figure 7 A schematic diagram of uniform rate temperature control provided by the present invention;

[0058] Figure 8 A high-precision control circuit diagram provided by the present invention. DETAILED DESCRIPTION

[0059] The core of the present invention is to provide a sterilization control method, system, sterilizer and medium for pharmaceutical packaging materials, which realizes accurate control of temperature rise during the sterilization process according to information from the sterilizer in operation, thereby improving the safety of the sterilization process.

[0060] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0061] Please refer to Figure 1 , Figure 1 The present invention provides a process flow chart of a sterilization control method for pharmaceutical packaging materials. The sterilizer is applied to a sterilizer, and the sterilizer includes: a heating device arranged in an inner chamber of the sterilizer, a cooling device arranged in an inner chamber of the sterilizer, and a control module arranged in the inner chamber of the sterilizer, and the control module is connected to the heating device and the cooling device respectively; the method includes:

[0062] S10: Determine whether the temperature of the inner chamber reaches a preset temperature;

[0063] In the present invention, in order to adjust the heating power of the heating device, it is necessary to ensure that the temperature of the inner chamber of the sterilizer reaches the preset temperature, so it is necessary to first determine whether the temperature of the inner chamber reaches the preset temperature, thereby ensuring the accuracy of the solution.

[0064] It should be noted that in actual applications, before the temperature of the inner chamber reaches the preset temperature, the sterilizer generally needs to perform several steps, specifically: 1. Perform water inlet control, and the water inlet pipe passes through a pure water filter and a pure water solenoid valve to bring the water level in the inner chamber to a predetermined water level; 2. After the water level is reached, the steam generated by the heating element and the exhaust pipe 111 are used to discharge the steam and air mixture through a filter and an exhaust solenoid valve to ensure the uniformity of the steam; 3. After the steam is discharged, it is necessary to condense the steam through a heat exchanger 21, and then condense it through a condensing device 24 for a second time. At the same time, there will be a low water level requirement in the steam collecting bottle 22 to ensure the secondary condensation effect of the condensing device 24. Finally, the excess steam is condensed three times in the steam collecting bottle 22 to ensure that there is no steam discharged; 4. A steam collecting bottle water level sensor 25 and an overflow port are provided in the steam collecting bottle 22 to ensure that when the condensed water in the steam collecting bottle 22 is full, the operator can be reminded to drain or overflow. When the temperature of the inner chamber reaches the boiling point (i.e., the preset temperature in the present invention), different process controls are entered according to different process curves. The specific process controls are as follows: Figure 2 The curves of uniform heating and cooling are shown in Figure 3 As shown in the figure, the curves of rapid heating and rapid cooling are as follows Figure 4 shown.

[0065] It should also be noted that the sterilizer is composed of multiple parts, specifically a cooling water inlet filter 1, a cooling water inlet valve 2, a cooling water inlet nozzle 13, a cooling water inlet nozzle 24, a movable temperature sensor 5, a sterilizer body and a sealed door 6, an insulation layer 7, a load basket 8, a sterilization load 9, a load support frame 10, a fixed temperature sensor 11, a pure water inlet filter 12, a pure water inlet valve 13, a power heating element 114, a power heating element 215, a power heating element 316, a cooling water inlet pipe 17, a pure water inlet pipe 18, an exhaust filter 19, an exhaust solenoid valve 20, a heat exchanger 21, a steam collecting bottle 22, an exhaust pipe 23, a condensing device 24, a steam collecting bottle water level sensor 25, an overflow interface 26, an inner chamber water level sensor 27, and a pressure sensor 28. The structure of the sterilizer is as follows Figure 5 shown.

[0066] It should also be noted that the heating device includes: a power heating element 114, a power heating element 215, and a power heating element 316; and the fixed temperature sensor 11 is disposed in the fixed probe.

[0067] S11: If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the heating rate and the current heating power of the current heating device are determined according to the operation information;

[0068] In the present invention, because it is necessary to judge whether the heating power needs to be adjusted based on the heating rate, if the temperature of the inner chamber reaches the preset temperature, the heating rate of the current heating device and the current heating power are determined based on the current operation information of the sterilizer, which is more convenient for subsequent judgment on whether the current heating power needs to be adjusted.

[0069] S12: judging whether the heating power needs to be adjusted based on the heating rate;

[0070] In the present invention, whether the heating power needs to be adjusted is judged based on the heating rate. The heating rate can be used to more accurately judge whether the heating power needs to be adjusted.

[0071] It should be noted that in actual application, the power is uniformly controlled by the system. The system includes: control system 101, heating module 102, exhaust control module 103, rapid cooling module 104, detection module 105, high-precision control circuit 106, heating device 1107, heating device 2108, heating device 3109, steam condensing device 110, exhaust pipeline 111, wastewater collection device 112, wide-angle nozzle 113, water inlet pipeline 114, movable temperature detection 115, pressure detection 116, fixed probe temperature detection 117, water level detection 118. The structure of the system is as follows: Figure 6As shown, the heating module 102 is used to control the output power of the heating device 1107, the heating device 2108, and the heating device 3109 by the high-precision control circuit 106 (control module) to heat the device, wherein the power of the three heating devices is different and is divided into three power gradients, and the temperature of the fixed temperature sensor 11 gradually increases under the heating condition.

[0072] S13: If the heating power needs to be adjusted, the heating power is adjusted to a preset power.

[0073] In the present invention, if the heating power needs to be adjusted, the heating power is adjusted to a preset power to achieve control of the heating during the sterilization process of the sterilizer.

[0074] The present embodiment provides a sterilization control method for pharmaceutical packaging materials, by judging whether the temperature of the inner chamber reaches a preset temperature. If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the heating rate and the current heating power of the current heating device are determined according to the operation information. Based on the heating rate, it is judged whether the heating power needs to be adjusted. If the heating power needs to be adjusted, the heating power is adjusted to the preset power. This realizes accurate control of the temperature rise during the sterilization process according to the information of the sterilizer in operation, thereby improving the safety of the sterilization process.

[0075] Based on the above embodiments:

[0076] As a preferred embodiment, judging whether the heating power needs to be adjusted based on the temperature of the sterilizer after the first preset time, and if the heating power needs to be adjusted, adjusting the heating power to the preset power includes:

[0077] Controlling the heating device to heat at a heating rate for a first preset time, and calculating the temperature of the sterilizer after the first preset time has passed;

[0078] determining a first temperature difference between a preset temperature and a temperature of the sterilizer after a first preset time;

[0079] determining a current percentage between the first temperature difference and a target first temperature difference;

[0080] If the current percentage is less than the first preset percentage, the heating power is adjusted to the first preset power;

[0081] If the current percentage is not less than the first preset percentage and greater than the second preset percentage, the heating power is adjusted to the second preset power; wherein the second preset power is less than the first preset power.

[0082] In the present invention, the heating device is controlled to heat at a heating rate for a first preset time, and the temperature of the sterilizer after heating is determined, and then the temperature difference before and after heating is determined, and then the current percentage between the temperature difference and the target first temperature difference is determined based on the temperature difference, and finally, according to the relationship between the current percentage and the first preset percentage and the second preset percentage, it is determined whether the heating power should be adjusted to the first preset power or the second preset power, so as to more accurately adjust the heating power.

[0083] It should be noted that, in actual applications, the first preset percentage is generally 50%, and the second preset percentage is generally 60%. When the percentage is within 50%, the output power P is fully heated (the power heating element 114, the power heating element 215, and the power heating element 316 are started at the same time). When the percentage exceeds 60%, the output power P is partially heated (the power heating element 114, the power heating element 215, and the power heating element 316 are partially started).

[0084] It should also be noted that in practical applications, uniform rate temperature control is Figure 7 shown.

[0085] As a preferred embodiment, calculating the temperature of the sterilizer after the first preset time has passed includes:

[0086] Calculating the product of the first preset time and the heating rate to obtain a temperature change value;

[0087] The temperature change value and the preset temperature are summed to obtain the temperature of the sterilizer after the first preset time has passed.

[0088] In the present invention, the method for calculating the temperature of the sterilizer after the first preset time is to calculate the product between the first preset time and the heating rate, and use the obtained product as the temperature change value, sum the temperature change value and the preset temperature to obtain the temperature of the sterilizer after the first preset time. The specific calculation process can be expressed by the formula: T1=V×F+T0, T1 is the temperature of the sterilizer after the first preset time; T0 is the preset temperature; V is the heating rate, unit ℃ / s; F is the first preset time, unit s, which can more accurately obtain the temperature of the sterilizer after the first preset time.

[0089] It should be noted that, in practical applications, the first preset time is generally 60 seconds, and may also be other durations, which is not particularly limited in the present invention.

[0090] It should also be noted that the control system 101 detects the temperature value of the fixed probe through the detection module 105, and calculates the temperature of the sterilizer after the first preset time according to the calculation formula.

[0091] As a preferred embodiment, before controlling the heating device to heat at a heating rate for a first preset time, the method further includes:

[0092] Determine the relationship between the heating rate and the preset rate;

[0093] If the heating rate is equal to the preset rate, triggering the step of controlling the heating device to heat at the heating rate for a first preset time;

[0094] If the heating rate is greater than the preset rate, the heating device is controlled to stop heating;

[0095] If the heating rate is less than the preset rate, the heating device is controlled to heat at the heating rate for a second preset time, and the second preset time is greater than the first preset time.

[0096] In the present invention, before controlling the heating device to heat at a heating rate for a first preset time, a judgment is made on the size relationship between the heating rate and the preset rate. If the heating rate is equal to the preset rate, it is proved that the heating rate is appropriate at this time, and the step of controlling the heating device to heat at the heating rate for the first preset time is performed; if the heating rate is greater than the preset rate, it is proved that the heating rate is too large at this time, and the heating device needs to be controlled to stop heating; if the heating rate is less than the preset rate, it is proved that the heating rate is too small, and the heating device needs to be controlled to heat at the heating rate for a second preset time (the second preset time is greater than the first preset time).

[0097] It should be noted that, in practical applications, the second preset time may be 10% longer than the first preset time, and the present invention does not make any special limitation thereto.

[0098] As a preferred embodiment, after controlling the heating device to heat at the heating rate for the first preset time, the method further comprises:

[0099] Determine the relationship between the current temperature of the interior room and the target temperature;

[0100] If the current temperature of the inner chamber is greater than or equal to the target temperature, determining whether the pressure of the inner chamber is less than a preset pressure value;

[0101] If the pressure in the inner chamber is lower than the preset pressure value, the cooling device is controlled to cool down;

[0102] If the current temperature of the inner chamber is lower than the target temperature, the heating device is controlled to heat at a heating rate for a first preset time, and the process jumps again to the step of determining the magnitude relationship between the current temperature of the inner chamber and the target temperature.

[0103] In the present invention, after controlling the heating device to heat at a heating rate for a first preset time, it is also necessary to determine the relationship between the current temperature of the inner chamber and the target temperature. If the current temperature of the inner chamber is greater than or equal to the target temperature, it is determined whether the pressure of the inner chamber is less than the preset pressure value. If the pressure of the inner chamber is less than the preset pressure value, the cooling device is controlled to cool down. If the current temperature of the inner chamber is less than the target temperature, it is necessary to control the heating device to heat at a heating rate for a first preset time, and re-determine the relationship between the current temperature of the inner chamber and the target temperature, thereby ensuring that the cooling device can carry out the cooling process normally and improving the safety and stability of the cooling process.

[0104] As a preferred embodiment, controlling the cooling device to cool down includes:

[0105] Controlling the cooling device to cool down the temperature at a target cooling rate for a first preset time, and calculating the temperature of the sterilizer after cooling down, wherein the target cooling rate is equal to the heating rate;

[0106] Determine a second temperature difference between the current temperature of the inner chamber and the temperature of the sterilizer after the temperature is reduced;

[0107] determining a current percentage between the second temperature difference and a target second temperature difference;

[0108] If the current percentage is less than the first preset percentage, the cooling power is adjusted to the first preset power;

[0109] If the current percentage is not less than the first preset percentage and greater than the second preset percentage, the cooling power is adjusted to the second preset power.

[0110] In the present invention, the process of controlling the cooling device to cool down is similar to the process of controlling the heating device to heat up. First, the second temperature difference between the current temperature of the inner chamber and the temperature of the sterilizer after cooling is determined; then the current percentage between the second temperature difference and the target second temperature difference is determined; if the current percentage is less than the first preset percentage, the cooling power is adjusted to the first preset power; if the current percentage is not less than the first preset percentage and greater than the second preset percentage, the cooling power is adjusted to the second preset power. The cooling process of the sterilizer is also controlled, thereby improving the safety of the sterilization process.

[0111] It should be noted that during the heating process, the heating module 102 controls all heating elements through the high-precision control circuit 106 and works at full power. After the temperature reaches a preset temperature (for example, 121°C), it enters the maintenance stage. After the maintenance time is up, it enters the rapid cooling stage. During the rapid cooling process, the cooling water inlet valve 2 is opened, and the cooling water is filtered through the cooling water filter, and then passes through the cooling water inlet valve 2 and the cooling water inlet pipe 17, and finally through the cooling water inlet nozzle 13 and the cooling water inlet nozzle 24, for 120° wide-angle spraying. The water mist is directly sprayed onto the sterilization load 9, thereby achieving the purpose of rapid cooling. When the movable temperature sensor 5 detects that the temperature of the sterilization load 9 reaches room temperature (default 25°C), the program ends.

[0112] As a preferred embodiment, after controlling the cooling device to cool down at the target cooling rate for a first preset time, the method further includes:

[0113] Determine the relationship between the current temperature of the inner chamber and the preset temperature;

[0114] If the current temperature of the inner chamber is less than or equal to the preset temperature, the cooling device is controlled to stop cooling;

[0115] If the current temperature of the inner chamber is greater than the preset temperature, the cooling device is controlled to cool at a target cooling rate for a first preset time, and the process jumps again to the step of determining the magnitude relationship between the current temperature of the inner chamber and the preset temperature.

[0116] In the present invention, after controlling the cooling device to cool down at the target cooling rate for the first preset time, it is also necessary to determine the relationship between the temperature of the inner room after cooling and the preset temperature; if the current temperature of the inner room is less than or equal to the preset temperature, the cooling device is controlled to stop cooling; if the current temperature of the inner room is greater than the preset temperature, the cooling device is controlled to cool down at the target cooling rate for the first preset time, and the relationship between the current temperature of the inner room and the preset temperature is re-determined, so as to more accurately control the cooling device to stop cooling.

[0117] The present invention also provides an embodiment corresponding to a sterilization control system for pharmaceutical packaging materials, which is applied to a sterilizer, wherein the sterilizer comprises: a heating device arranged in an inner chamber of the sterilizer, a cooling device arranged in an inner chamber of the sterilizer, and a control module arranged in the inner chamber of the sterilizer, wherein the control module is connected to the heating device and the cooling device respectively; the system comprises:

[0118] A first judging unit, configured to judge whether the temperature of the inner chamber reaches a preset temperature, and if so, trigger the determining unit;

[0119] A determination unit, used to determine the current operation information of the sterilizer, and determine the heating rate and current heating power of the current heating device according to the operation information;

[0120] A second judging unit, configured to judge whether the heating power needs to be adjusted based on the heating rate, and if so, trigger the adjusting unit;

[0121] The adjusting unit is used to adjust the heating power to a preset power.

[0122] Since the embodiments of the sterilization control system part of pharmaceutical packaging materials correspond to the embodiments of the method part, please refer to the description of the embodiments of the method part for the embodiments of the sterilization control system part of pharmaceutical packaging materials, which will not be repeated here.

[0123] The present invention also provides a corresponding embodiment of a sterilizer, including:

[0124] A heating device disposed in the sterilizer chamber;

[0125] A cooling device provided in the sterilizer chamber;

[0126] A control module is arranged in the inner chamber of the sterilizer, and the control module is connected to the heating device and the cooling device respectively, and is used to implement the steps of the sterilization control method for pharmaceutical packaging materials as described above when executing a computer program.

[0127] Since the embodiments of the sterilizer part correspond to the embodiments of the method part, please refer to the description of the embodiments of the method part for the embodiments of the sterilizer part, which will not be repeated here.

[0128] It should be noted that after the control module (high-precision control circuit 106) is powered on, the U19 level conversion chip starts to work. When the control signal is not generated, due to the pull-down effect of R63 / R64 / R65, U19 outputs a high level, the optocoupler OTP1 is not turned on, and the thyristor turns off the output and remains in a safe state. 101- The MCU main control chip in the control system 101 sends a control signal, Q14 / Q15 / Q16, etc. are from the MCU chip. When the signal is high, the nA to nY output of the U19 inverter is low. The low-level signal controls the PIN2_CAT pin of the optocoupler OTP1. When this pin is low, the +5V power supply pulls up the diode anode ANO pin of the optocoupler OTP1 through the RO3 resistor, and the current passes through RO3 and the light-emitting diode of the optocoupler OTP1. After the diode is turned on, the output terminals MT1 and MT2 are closed. When the +5V power supply passes through the RO5 resistor and the light-emitting diode Q14, this diode is lit. When MT1 and MT2 are turned on, the voltage passes through RO6 to apply the forward voltage to the control electrode of PIN3 of thyristor ACQ1, and then passes through RO4 to the other end of AC220. At this time, PION1 and PIN2 of thyristor ACQ1 are turned on. CO1 and RO7 form a resistor-capacitor filter to filter the sudden interference of high-frequency and high-voltage to protect the thyristor. VR1 varistor clamps the excessive surge voltage, and the resistor-capacitor filter forms a double protection.

[0129] During the control process, we can control the actions of ACQ1, ACQ2, and ACQ3 by outputting output signals of different high and low frequencies through the MCU main control chip in the control system 101, and finally realize the heating frequency and heating time function not exceeding 100Hz. The structure of the control module is as follows: Figure 8 shown.

[0130] The present invention also provides an embodiment corresponding to a computer-readable storage medium, on which a computer program is stored, and when the computer program is executed by a processor, the steps of the sterilization control method for pharmaceutical packaging materials as described above are implemented.

[0131] It is understandable that if the method in the above embodiment is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present application is essentially or the part that contributes to the prior art or all or part of the technical solution can be embodied in the form of a software product, and the computer software product is stored in a storage medium to execute all or part of the steps of the methods of each embodiment of the present application. The aforementioned storage medium includes: U disk, mobile hard disk, read-only memory (ROM), random access memory (RAM), disk or optical disk and other media that can store program code.

[0132] Since the embodiments of the computer-readable storage medium part correspond to the embodiments of the method part, please refer to the description of the embodiments of the method part for the embodiments of the computer-readable storage medium part, which will not be repeated here.

[0133] It should be noted that, in this specification, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "comprise", "include" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the statement "comprises a ..." does not exclude the presence of other identical elements in the process, method, article or device including the element.

[0134] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A sterilization control method for pharmaceutical packaging materials, characterized in that: Applied to a sterilizer, the sterilizer comprises: a heating device arranged in an inner chamber of the sterilizer, a cooling device arranged in the inner chamber of the sterilizer, and a control module arranged in the inner chamber of the sterilizer, the control module being connected to the heating device and the cooling device respectively; the method comprises: Determining whether the temperature of the inner chamber reaches a preset temperature; If the temperature of the inner chamber reaches the preset temperature, the current operation information of the sterilizer is determined, and the current heating rate and the current heating power of the heating device are determined according to the operation information; Controlling the heating device to heat at the heating rate for a first preset time, and calculating the temperature of the sterilizer after the first preset time has passed; determining a first temperature difference between the preset temperature and the temperature of the sterilizer after the first preset time has elapsed; determining a current percentage between the first temperature difference and a target first temperature difference; If the current percentage is less than the first preset percentage, adjusting the heating power to the first preset power; If the current percentage is not less than the first preset percentage and greater than the second preset percentage, the heating power is adjusted to the second preset power; wherein the second preset power is less than the first preset power.

2. The sterilization control method for pharmaceutical packaging materials according to claim 1, characterized in that: Calculating the temperature of the sterilizer after the first preset time has passed, comprising: Calculating the product of the first preset time and the heating rate to obtain a temperature change value; The temperature change value and the preset temperature are summed to obtain the temperature of the sterilizer after the first preset time has passed.

3. The sterilization control method for pharmaceutical packaging materials according to claim 1, characterized in that: Before controlling the heating device to heat at the heating rate for a first preset time, the method further includes: Determining the magnitude relationship between the heating rate and a preset rate; If the heating rate is equal to the preset rate, triggering the step of controlling the heating device to heat at the heating rate for a first preset time; If the heating rate is greater than the preset rate, controlling the heating device to stop heating; If the heating rate is less than the preset rate, the heating device is controlled to heat at the heating rate for a second preset time, and the second preset time is greater than the first preset time.

4. The sterilization control method for pharmaceutical packaging materials according to any one of claims 1 to 3, characterized in that: After controlling the heating device to heat at the heating rate for a first preset time, the method further comprises: Determining the magnitude relationship between the current temperature of the inner chamber and the target temperature; If the current temperature of the inner chamber is greater than or equal to the target temperature, determining whether the pressure of the inner chamber is less than a preset pressure value; If the pressure of the inner chamber is lower than the preset pressure value, controlling the cooling device to cool down; If the current temperature of the inner chamber is lower than the target temperature, the heating device is controlled to heat at the heating rate for the first preset time, and the process jumps again to the step of determining the magnitude relationship between the current temperature of the inner chamber and the target temperature.

5. The sterilization control method for pharmaceutical packaging materials according to claim 4, characterized in that: Controlling the cooling device to cool down the temperature includes: Controlling the cooling device to cool down the first preset time at a target cooling rate, and calculating the temperature of the sterilizer after cooling, wherein the target cooling rate is equal to the heating rate; Determining a second temperature difference between the current temperature of the inner chamber and the temperature of the sterilizer after the temperature is reduced; determining a current percentage between the second temperature difference and a target second temperature difference; If the current percentage is less than the first preset percentage, the cooling power is adjusted to the first preset power; If the current percentage is not less than the first preset percentage and greater than the second preset percentage, the cooling power is adjusted to the second preset power.

6. The sterilization control method for pharmaceutical packaging materials according to claim 5, characterized in that: After controlling the cooling device to cool down at the target cooling rate for the first preset time, the method further includes: Determining the magnitude relationship between the current temperature of the inner chamber and the preset temperature; If the current temperature of the inner chamber is less than or equal to the preset temperature, controlling the cooling device to stop cooling; If the current temperature of the inner chamber is greater than the preset temperature, the cooling device is controlled to cool at the target cooling rate for the first preset time, and the process jumps again to the step of determining the magnitude relationship between the current temperature of the inner chamber and the preset temperature.

7. A sterilization control system for pharmaceutical packaging materials, characterized in that: Applied to a sterilizer, the sterilizer comprises: a heating device arranged in an inner chamber of the sterilizer, a cooling device arranged in an inner chamber of the sterilizer, and a control module arranged in the inner chamber of the sterilizer, the control module being connected to the heating device and the cooling device respectively; the system comprises: a first judging unit, configured to judge whether the temperature of the inner chamber reaches a preset temperature, and if so, trigger the determining unit; The determining unit is used to determine the current operation information of the sterilizer, and determine the current heating rate and the current heating power of the heating device according to the operation information; a second judgment unit, configured to control the heating device to heat at the heating rate for a first preset time, and calculate the temperature of the sterilizer after the first preset time; determine a first temperature difference between the preset temperature and the temperature of the sterilizer after the first preset time; determine a current percentage between the first temperature difference and a target first temperature difference, and trigger an adjustment unit if the current percentage is less than a first preset percentage, or if the current percentage is not less than the first preset percentage and greater than a second preset percentage; The adjustment unit is used to adjust the heating power to the first preset power if the current percentage is less than the first preset percentage; if the current percentage is not less than the first preset percentage and greater than the second preset percentage, adjust the heating power to the second preset power; wherein the second preset power is less than the first preset power.

8. A sterilizer, characterized in that: include: A heating device disposed in the sterilizer chamber; A cooling device provided in the sterilizer chamber; A control module is arranged in the inner chamber of the sterilizer, and the control module is connected to the heating device and the cooling device respectively, and is used to implement the steps of the sterilization control method of the pharmaceutical packaging material as claimed in any one of claims 1 to 6 when executing the computer program.

9. A computer-readable storage medium, characterized in that: The computer-readable storage medium stores a computer program, and when the computer program is executed by a processor, the steps of the sterilization control method for pharmaceutical packaging materials according to any one of claims 1 to 6 are implemented.

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