Preparation method of a nanofiber membrane with coexisting hydrophilicity and hydrophobicity

Abstract

The application provides a preparation method of a hydrophilic and hydrophobic coexisting nanofiber membrane, and the nanofiber membrane is directly prepared in situ on the skin by using electrostatic spinning method with PVB / PVP as the material. The two structures of PVB / PVP are independent and coexist, the hydrophilic PVP of the prepared nanofiber membrane is dissolved, the adhesion with the skin is increased, the hydrophobic PVB maintains the original structure, the existence of the membrane is maintained, meanwhile, the water loss in the membrane is blocked, and the effect of moisture retention is achieved. When used, the nanofiber membrane can be prepared after the skin is coated with a moisturizing skin care product, and the action time of the skin care product can be effectively prolonged and the skin can be kept moist after the film is formed.

Description

Technical Field

[0001] This invention relates to the field of nanomembrane material technology, and more particularly to a method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties. Background Technology

[0002] Traditional face masks have complex manufacturing processes and long production cycles. Furthermore, for one of the most important aspects of skincare—moisturizing—face masks often lack sufficient hydration. Most masks dry out within 15-20 minutes of use, significantly reducing the effectiveness of the skincare essence on the skin. In addition, most face masks are mass-produced by combining non-woven fabric with a specific skincare essence, making it impossible to offer multiple benefits.

[0003] In recent years, electrospinning technology has seen rapid development and application in fields such as biology, medicine, and sensing. This technology utilizes electrostatic high voltage to charge polymer fibers into filaments, which can then be deposited into films with certain mechanical properties. By adding other functional materials to the polymer, the resulting film can possess different functional characteristics. Compared to traditional non-woven fabric masks, electrospinning fiber film formation technology is more convenient and faster, especially with the advent of portable electrospinning guns, which allow for rapid in-situ film formation.

[0004] Traditional coating methods require pre-fabricated finished products before use, while advanced electrospinning technology enables in-situ coating, making it more convenient and faster. However, most coating materials produced using electrospinning technology currently possess only single hydrophilic or hydrophobic properties, limiting their application areas. Therefore, it is particularly important to develop a highly efficient and convenient coating composition with both hydrophilic and hydrophobic properties, applicable to a wide range of fields, based on electrospinning technology. Applications include moisturizing and preventing moisture loss, such as skin hydration and fruit preservation.

[0005] To address the issues of poor moisturizing properties in face masks and the fact that each mask only offers a single function, a water-resistant coating composition needs to be developed. This coating composition should be combined with electrospinning technology to achieve efficient in-situ film formation, while also being compatible with various skincare products to prolong moisturizing effects and increase the skin's absorption time of the active ingredients in the skincare serum.

[0006] In view of this, it is necessary to improve the existing technology of keeping face masks moist for a long time in order to solve the above problems. Summary of the Invention

[0007] The purpose of this invention is to disclose a method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties. This membrane can be hydrophilic and adhere closely to the skin to form a film, while also being hydrophobic on the outside to moisturize, which greatly improves the adhesion to the skin and the moisturizing effect.

[0008] To achieve the above objectives, the present invention provides a method for preparing nanofiber membranes with both hydrophilic and hydrophobic properties, comprising the following steps:

[0009] Step 1: Weigh a certain amount of PVB (polyvinyl butyral) powder and dissolve it in anhydrous ethanol;

[0010] Step 2: Weigh a certain amount of PDMS (polydimethylsiloxane) and add it to the above mixture, then stir until homogeneous to obtain a PVB / PDMS solution;

[0011] Step 3: Weigh a certain amount of PVP (polyvinylpyrrolidone) powder and add it to anhydrous ethanol to dissolve it and obtain a PVP solution;

[0012] Step 4: Mix the PVB / PDMS solution and PVP solution in the specified ratio until homogeneous to obtain a PVB / PDMS / PVP mixture.

[0013] Step 5: Prepare nanofiber membranes by electrospinning using a dressing gun.

[0014] In some embodiments, the following steps are also included: applying a skin care product to the skin, and then preparing a nanofiber membrane on the skin by electrospinning; after standing for 15-20 minutes, peeling off the nanofiber membrane.

[0015] In some embodiments, in step one, 11 parts of PVB powder are weighed and dissolved in 100 parts of anhydrous ethanol.

[0016] In some embodiments, in step three, 11 parts of PVP powder are weighed and added to 100 parts of anhydrous ethanol to dissolve and obtain a PVP solution.

[0017] In some embodiments, in step four, 3-7 parts of PVB / PDMS solution and 3-7 parts of PVP solution are weighed and stirred to obtain a PVB / PDMS / PVP mixture.

[0018] In some embodiments, the electrospinning working conditions in step five are: a voltage of 8-12kV, a feeding speed of 1.5-3mL / h, and a receiving distance of 8-20cm.

[0019] In some embodiments, the skin care product is a moisturizing skin care product.

[0020] In some embodiments, the moisturizing skincare product is one or more of serums, creams, and collagen solutions.

[0021] Compared with the prior art, the beneficial effects of the present invention are: the membrane composition can be in-situ coated with an electrospinning gun, making the preparation method convenient; after film formation, it is both hydrophilic and hydrophobic. After the fiber membrane is formed in situ on the skin surface, the inner side of the membrane surface that adheres to the skin has good hydrophilicity, while the membrane surface exposed to dry air has good hydrophobicity, thus forming a barrier that locks moisture in the inner side of the membrane surface, achieving a moisturizing effect; it can also be combined with different skin care products to prepare a coating composition, reducing the evaporation of skin care products exposed to air and achieving a good absorption effect of slow release of skin care products into the skin. Attached Figure Description

[0022] Figure 1 Microscopic dimensions of nanofiber membranes with different polymer dosages;

[0023] Figure 2 The diagram shows the changes in the microstructure of nanofiber membranes after dissolving PVP with water vapor under different polymer dosages.

[0024] Figure 3 A comparison of the hydrophilicity and hydrophobicity of electrospun membranes made from PVP solution and PVB / PDMS / PVP solution.

[0025] Figure 4 This is a diagram showing the water contact angle for different polymer contents. Detailed Implementation

[0026] The present invention will now be described in detail with reference to the embodiments shown in the accompanying drawings. However, it should be noted that these embodiments are not intended to limit the present invention. Equivalent changes or substitutions in function, method, or structure made by those skilled in the art based on these embodiments are all within the scope of protection of the present invention.

[0027] PVB (polyvinyl butyral), a commonly used support material, is a resin that easily adheres to various surfaces, is highly tough and elastic, and has strong bonding strength and high optical clarity.

[0028] PVP (polyvinylpyrrolidone) offers both hydrophilic and lipophilic chemistry and has been used as an excipient in several conventional, controlled, and novel drug delivery systems due to its solubility and availability in various grades, providing effects such as film formation, complexation, solubilization, adhesion, stabilization, suspension, thickening, and others. PVP has been found in numerous biomedical applications, and its unique properties include amphiphilicity, hydrogen bonding and complexation, solubility, and compatibility with other polymers and therapeutic agents. With advancements in technologies such as electrospinning, electrospraying, and 3D / 4D printing, PVP has been identified as an ideal material for preparing nanofibers.

[0029] A method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties includes the following steps:

[0030] Step 1: Weigh a certain amount of PVB (polyvinyl butyral) powder and dissolve it in anhydrous ethanol;

[0031] Step 2: Weigh a certain amount of PDMS (polydimethylsiloxane) and add it to the above mixture, then stir until homogeneous to obtain a PVB / PDMS solution;

[0032] Step 3: Weigh a certain amount of PVP (polyvinylpyrrolidone) powder and add it to anhydrous ethanol to dissolve it and obtain a PVP solution;

[0033] Step 4: Mix the PVB / PDMS solution and PVP solution in the specified ratio until homogeneous to obtain a PVB / PDMS / PVP mixture.

[0034] Step 5: Prepare nanofiber membranes by electrospinning using a dressing gun.

[0035] In step one, 11 parts of PVB powder are weighed and dissolved in 100 parts of anhydrous ethanol; in step three, 11 parts of PVP powder are weighed and dissolved in 100 parts of anhydrous ethanol to obtain a PVP solution; in step four, 3-7 parts of PVB / PDMS solution and 3-7 parts of PVP solution are weighed and stirred to obtain a PVB / PDMS / PVP mixture; in step five, the electrospinning working conditions are: voltage value of 8-12kV, feeding speed of 1.5-3mL / h, and receiving distance of 8-20cm.

[0036] The nanofiber membrane prepared in this embodiment has good hydrophilicity and hydrophobicity.

[0037] The nanofiber membrane prepared by the above method can be used to prepare a mask substrate. The membrane can be formed in situ on the skin surface using a dressing gun. After the membrane is formed, the inner side of the membrane that is close to the skin has good hydrophilicity, while the membrane surface exposed to dry air has good hydrophobicity, thus forming a barrier that locks moisture in the inner side of the membrane surface, achieving a moisturizing effect.

[0038] It can be used in conjunction with different skin care products to form a film in place, reducing the evaporation of skin care products exposed to the air and achieving a good absorption effect of slow release of skin care products into the skin.

[0039] Therefore, the above preparation method also includes the following steps: applying the skin care product to the skin, and then preparing a nanofiber membrane on the skin by electrospinning; after standing for 15-20 minutes, peeling off the nanofiber membrane.

[0040] The skincare product is a moisturizing skincare product. In this embodiment, the moisturizing skincare product is one or more of the following: serum, cream, and collagen solution.

[0041] like Figure 1-4 As shown, Figure 1 These are the microstructures of nanofiber membranes with different polymer dosages (PVB content gradually increases from left to right). Figure 2 These are diagrams showing the changes in the microstructure of nanofiber membranes after PVP dissolution with water vapor at different polymer dosages (corresponding to...). Figure 1 (Amount of polymer used) Figure 3 This is a comparison of the hydrophilicity and hydrophobicity of electrospun membranes made from PVP solution and PVB / PDMS / PVP solution. Figure 4 This is a water contact angle diagram for different polymer contents (PVB content gradually increases from left to right).

[0042] from Figure 1-4 It can be seen from this that Figure 1 The transparent, linear structure is a PVP microstructure, which, after being dissolved by water vapor, Figure 2 The microstructure of PVP was dissolved, while the microstructure of PVB remained unchanged. Furthermore, with increasing PVB content, the retained structure became increasingly dense, indicating that the two structures coexisted independently. This result validates the hydrophilic dissolution of PVP after coating, increasing its adhesion to the skin; while PVB, being hydrophobic, maintained its original structure, preserving the membrane and preventing moisture loss, thus achieving a moisturizing effect and prolonging the action time of skincare products.

[0043] like Figure 3 As shown, the PVP membrane on the left is hydrophilic, but becomes hydrophobic after the addition of PVB / PDMS. Figure 4 As shown, with the increase of PVB content, the contact angle of the nanofiber membrane increases from 30° to 131°.

[0044] The detailed descriptions listed above are merely specific descriptions of feasible embodiments of the present invention, and are not intended to limit the scope of protection of the present invention. All equivalent embodiments or modifications made without departing from the spirit of the present invention should be included within the scope of protection of the present invention.

[0045] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties, characterized in that, Includes the following steps: Step 1: Weigh a certain amount of PVB (polyvinyl butyral) powder and dissolve it in anhydrous ethanol; Step 2: Weigh a certain amount of PDMS (polydimethylsiloxane) and add it to the above mixture, then stir until homogeneous to obtain a PVB / PDMS solution; Step 3: Weigh a certain amount of PVP (polyvinylpyrrolidone) powder and add it to anhydrous ethanol to dissolve it and obtain a PVP solution; Step 4: Mix the PVB / PDMS solution and PVP solution in the specified ratio until homogeneous to obtain a PVB / PDMS / PVP mixture. Step 5: Prepare nanofiber membranes in situ on the skin surface using a dressing gun via electrospinning. The working conditions for electrospinning are: voltage 8-12kV, feeding speed 1.5-3 mL / h, and receiving distance 8-20 cm.

2. The method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties according to claim 1, characterized in that, It also includes the following steps: Apply skincare products to the skin, and then prepare a nanofiber membrane on the skin by electrospinning; after standing for 15-20 minutes, peel off the nanofiber membrane.

3. The method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties according to claim 1, characterized in that, In step one, 11 parts of PVB powder are weighed and dissolved in 100 parts of anhydrous ethanol.

4. The method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties according to claim 3, characterized in that, In step three, 11 parts of PVP powder are weighed and added to 100 parts of anhydrous ethanol to dissolve and obtain a PVP solution.

5. The method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties according to claim 4, characterized in that, In step four, 3-7 parts of PVB / PDMS solution and 3-7 parts of PVP solution are weighed and stirred to obtain a PVB / PDMS / PVP mixture.

6. The method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties according to claim 2, characterized in that, The skincare product in question is a moisturizing skincare product.

7. The method for preparing a nanofiber membrane with both hydrophilic and hydrophobic properties according to claim 6, characterized in that, The moisturizing skincare products mentioned are one or more of the following: serums, creams, and collagen solutions.

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