A tertiary amine group functionalized silver-loaded glass antibacterial agent, and a preparation method and application thereof

Abstract

The application relates to the field of antibacterial agents, in particular to a tertiary amine group functionalized silver-loaded glass antibacterial agent and a preparation method and application thereof; a preparation method of a tertiary amine group functionalized silver-loaded glass antibacterial agent is provided, and the steps include the following: S1, boron trioxide, silicon dioxide, sodium oxide and silver nitrate are weighed according to weight fractions, mixed and sequentially subjected to smelting treatment, cooling treatment and crushing treatment to prepare silver-loaded glass; S2, the silver-loaded glass is subjected to modification and activation treatment by using dimethyl vinyl chlorosilane ethanol aqueous solution to prepare modified and activated silver-loaded glass, monomers, initiators and crosslinking agents are added into the modified and activated silver-loaded glass to carry out free radical polymerization reaction, and washing and drying treatment is carried out, so that the tertiary amine group functionalized silver-loaded glass antibacterial agent is obtained; the tertiary amine group functionalized silver-loaded glass antibacterial agent of the application achieves the effect of high-efficiency bacteriostasis through the synergistic effect of silver and the tertiary amine group; the filter core shell prepared by the application can prevent initial adhesion and aggregation of bacteria and other microorganisms.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of antibacterial agents, in particular to a tertiary amine group functionalized silver-loaded glass antibacterial agent and a preparation method and application thereof. BACKGROUND

[0002] In recent years, with the rapid development of industrial economy, air pollution seriously affects people's health, and the development of household water purification, medical and pharmaceutical and food industries also puts forward higher requirements for air cleanliness. At present, air filter core filtration is one of the more effective ways of air purification.

[0003] The existing air filter core assembly provides favorable conditions for the growth and reproduction of microorganisms inside, causing air filter core microbial contamination. The existing air filter core assembly shell has high hydrophobicity, and the initial adhesion of bacteria and other microorganisms on the material surface is high, which leads to microbial contamination of ordinary air filter core assemblies after a period of use if not cleaned in time, thereby affecting the performance of the air filter core. In addition, cleaning the air filter core assembly not only increases the labor / time cost, but also reduces the user experience.

[0004] Therefore, there is an urgent need for an antibacterial agent that can prevent the initial adhesion and aggregation of bacteria and other microorganisms, thereby inhibiting the growth and reproduction of bacteria inside and on the surface of the air filter core assembly. SUMMARY

[0005] The purpose of the present application is to overcome the shortcomings of the prior art and provide a tertiary amine group functionalized silver-loaded glass antibacterial agent and a preparation method and application thereof.

[0006] To achieve the above-mentioned purpose, the technical solution adopted by the present application is:

[0007] The first aspect of the present application is to provide a preparation method of a tertiary amine group functionalized silver-loaded glass antibacterial agent, comprising the following steps:

[0008] S1. Weigh boron trioxide, silicon dioxide, sodium oxide and silver nitrate by weight fraction, mix and sequentially perform melting treatment, cooling treatment and crushing treatment to obtain silver-loaded glass;

[0009] S2. Modify and activate the silver-loaded glass with dimethylvinylchlorosilane ethanol aqueous solution to obtain modified and activated silver-loaded glass. Add monomer, initiator and crosslinking agent to the modified and activated silver-loaded glass to perform free radical polymerization reaction, and perform washing and drying treatment to obtain the tertiary amine group functionalized silver-loaded glass antibacterial agent.

[0010] Preferably, in step S1, the mass ratio of the boron trioxide, the silicon dioxide, the sodium oxide and the silver nitrate is (30-35):(50-55):(5-15).

[0011] Preferably, in step S1, the smelting process comprises: after the mixed boron trioxide, silicon dioxide, sodium oxide and silver nitrate are heated to 1300-1330℃ at a heating rate of 3-5℃ / min, holding for 20-40min.

[0012] Preferably, in the aqueous ethanol solution of dimethylvinylchlorosilane, the volume fraction of dimethylvinylchlorosilane is 1-3%.

[0013] Preferably, the monomer comprises diethylamine; the initiator comprises 2,2-azoisobutyronitrile; and the crosslinking agent comprises ethylene glycol dimethacrylate.

[0014] Preferably, in step S2, the molar ratio of the modified activated silver-loaded glass, the monomer, the initiator and the crosslinking agent is (1-3):(6-9):1:(1-3).

[0015] Preferably, in step S2, the washing and drying process comprises: after washing with deionized water, ethanol and acetone in sequence, the reaction product is subjected to a drying process.

[0016] The second aspect of the present application is to provide a tertiary amine functionalized silver-loaded glass antibacterial agent prepared by the above preparation method.

[0017] The third aspect of the present application is to provide an air filter element assembly, at least a part of which is made of a tertiary amine functionalized silver-loaded glass antibacterial material, which is prepared by the above preparation method or as described above.

[0018] Preferably, the air filter element assembly comprises: a filter element shell, a filter element cover bottom arranged at the inner top end of the filter element shell, a filter element filter screen arranged in the filter element shell, and a filter element end cover detachably connected to the bottom end of the filter element shell.

[0019] The filter element shell is made of a mixture of the tertiary amine functionalized silver-loaded glass antibacterial agent and a resin; the middle part of the filter element shell is provided with an air inlet along the radial direction of the filter element shell; the cross section of the filter element filter screen is annular, and the inner wall top end of the filter element shell and the top end of the filter element filter screen form a first gap, and the inner wall of the filter element shell and the outer wall of the filter element filter screen form a second gap.

[0020] The filter element cover bottom has a first part arranged in the first gap, a plurality of second parts arranged in the second gap are arranged on the outer periphery of the first part, and a third part arranged in a third gap formed by the inner ring of the filter element filter screen is arranged in the middle part of the first part.

[0021] The fourth gap is formed between the bottom end of the inner wall of the filter core shell and the bottom end of the filter core filter screen; the filter core end cover has a fourth part arranged in the fourth gap, the outer peripheral top end of the fourth part is provided with a plurality of fifth parts arranged in the second gap, the second part has a fifth gap between the bottom end and the top end of the fifth part; the middle top end of the fourth part is provided with a sixth part arranged in the third gap, the sixth part has a sixth gap between the top end and the bottom end of the third part; the middle bottom end of the fourth part is provided with a seventh part extending to the outside of the filter core shell; a sealing ring is sleeved on the outer wall of the seventh part; the middle part of the filter core end cover is provided with an air outlet penetrating through the seventh part and the sixth part.

[0022] Preferably, the outer peripheral bottom end of the fourth part is provided with a plurality of eighth parts extending to the outside of the bottom end of the filter core shell.

[0023] Preferably, the cross section of the filter core filter screen perpendicular to the axial direction of the filter core shell is annular.

[0024] Preferably, the resin comprises at least one of polyethylene or polypropylene.

[0025] Compared with the prior art, the above technical scheme has the following technical effects:

[0026] The tertiary amine group functionalized silver-loaded glass antibacterial agent of the application achieves high-efficiency bacteriostatic effect through the synergistic effect of silver and the tertiary amine group, silver reacts with the sulfhydryl group (-SH) of the cell membrane protein of bacteria and other microorganisms, and silver acts as a catalytic center to induce the production of reactive oxygen species (ROS), thereby achieving persistent, efficient and broad-spectrum antibacterial performance; the tertiary amine group can spontaneously present nitrogen (N)-protonation induction, contact and damage the negatively charged cell wall of bacteria and other microorganisms, and effectively inhibit the growth and reproduction of bacteria; the filter core shell made of the tertiary amine group functionalized silver-loaded glass antibacterial agent of the application can prevent the initial adhesion and aggregation of bacteria and other microorganisms, thereby inhibiting the growth and reproduction of bacteria inside and on the surface of the air filter core assembly; at the same time, the filter core shell of the application is not prone to discoloration. BRIEF DESCRIPTION OF DRAWINGS

[0027] Fig. 1 It is a basic structure schematic diagram of the air filter core assembly in an embodiment of the application;

[0028] Fig. 2 It is a sectional view of the air filter core assembly in an embodiment of the application;

[0029] The reference signs in the drawings include:

[0030] Filter core shell 1; filter core cover bottom 2; filter core filter screen 3; filter core end cover 4; sealing ring 5; air inlet 6; air outlet 7. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of the present application.

[0032] It should be noted that the embodiments in the present application and the features in the embodiments can be combined with each other without conflict.

[0033] The present application will be further described below with reference to the drawings and specific embodiments, but is not limited to the present application.

[0034] Embodiment 1

[0035] As shown in the drawings, the present embodiment provides an air filter assembly, comprising: a filter core shell 1, a filter core cover bottom 2 arranged at the top end inside the filter core shell 1, a filter core filter screen 3 arranged inside the filter core shell 1, and a filter core end cover 4 detachably connected with the bottom end of the filter core shell 1. Figs. 1-2 Among them, the filter core shell 1 adopts a mixture material of the tertiary amine group functionalized silver-loaded glass antibacterial agent and the resin; the middle part of the filter core shell 1 is provided with an air inlet 6 along the radial direction of the filter core shell 1; the cross section of the filter core filter screen 3 is annular, and a first gap is formed between the top end of the inner wall of the filter core shell 1 and the top end of the filter core filter screen 3, and a second gap is formed between the inner wall of the filter core shell 1 and the outer wall of the filter core filter screen 3.

[0036] The filter core cover bottom 2 has a first part arranged in the first gap, a plurality of second parts arranged in the second gap are arranged on the outer periphery of the first part, and a third part arranged in a third gap formed by the inner ring of the filter core filter screen 3 is arranged in the middle part of the first part.

[0037]

[0038] ​The fourth gap is formed between the inner wall bottom end of the filter core shell 1 and the bottom end of the filter core filter screen 3; the filter core end cover 4 has a fourth part, the fourth part is arranged in the fourth gap, the outer peripheral top end of the fourth part is provided with a plurality of fifth parts, the fifth parts are arranged in the second gap, the bottom end of the second part and the top end of the fifth part have a fifth gap; the outer peripheral bottom end of the fourth part is provided with a plurality of eighth parts, the eighth parts extend to the outside of the bottom end of the filter core shell 1; the middle top end of the fourth part is provided with a sixth part, the sixth part is arranged in the third gap, the top end of the sixth part and the bottom end of the third part have a sixth gap; the middle bottom end of the fourth part is provided with a seventh part, the seventh part extends to the outside of the filter core shell 1; the sealing ring 5 is sleeved on the outer wall of the seventh part; the middle part of the filter core end cover 4 is provided with an air outlet 7, the air outlet 7 penetrates through the seventh part and the sixth part.

[0039] Embodiment 2

[0040] The embodiment provides a preparation method of a filter core shell, and steps include:

[0041] S1, boron trioxide, silicon dioxide, sodium oxide and silver nitrate are weighed according to weight fractions, mixed and sequentially subjected to melting treatment, cooling treatment and crushing treatment to obtain silver-loaded glass; the mass ratio of the boron trioxide, the silicon dioxide, the sodium oxide and the silver nitrate is 30:50:10;5;

[0042] The melting treatment comprises: the boron trioxide, the silicon dioxide, the sodium oxide and the silver nitrate are placed in a platinum-gold crucible, heated to 1300℃ at a heating rate of 5℃ / min in a silicon-molybdenum furnace, and then kept for 30 min;

[0043] S2, the silver-loaded glass is subjected to modification and activation treatment for 24 h by using an ethanol aqueous solution of dimethylvinylchlorosilane with a volume fraction of 2% to obtain modified and activated silver-loaded glass, diethylamine, 2,2-azoisobutyronitrile and ethylene glycol dimethacrylate are added to the modified and activated silver-loaded glass, and a free radical polymerization reaction is carried out under vacuum at 65℃ for 24 h, and then the reaction product is sequentially washed and dried by using deionized water, ethanol and acetone to obtain a tertiary amine group functionalized silver-loaded glass antibacterial agent;

[0044] The molar ratio of the modified and activated silver-loaded glass, the diethylamine, the 2,2-azoisobutyronitrile and the ethylene glycol dimethacrylate is 2:8:1:2;

[0045] S3, drying the polyethylene, polypropylene and the tertiary amine group functionalized silver-loaded glass antibacterial agent at 65-75°C, then weighing the polyethylene, polypropylene and the tertiary amine group functionalized silver-loaded glass antibacterial agent, mixing them uniformly at 230°C, and then extruding, cooling and granulating to obtain a tertiary amine group functionalized silver-loaded glass antibacterial master batch; in the tertiary amine group functionalized silver-loaded glass antibacterial master batch, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial agent is 13%.

[0046] S4, uniformly adding the tertiary amine group functionalized silver-loaded glass antibacterial master batch into the polyethylene and polypropylene, and then injecting the mixture into an injection molding machine to obtain the filter core shell; in the filter core shell, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial master batch is 3%.

[0047] Example 3

[0048] This example provides another method for preparing a filter core shell, comprising the following steps:

[0049] S1, same as step S1 in Example 2;

[0050] S2, same as step S2 in Example 2;

[0051] S3, in the tertiary amine group functionalized silver-loaded glass antibacterial master batch, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial agent is 15%; the rest is the same as step S3 in Example 2;

[0052] S4, in the filter core shell, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial master batch is 5%; the rest is the same as step S4 in Example 2.

[0053] Comparative Example 1

[0054] This comparative example provides another method for preparing a filter core shell, comprising the following steps:

[0055] S1, same as step S1 in Example 3;

[0056] S2, replacing the tertiary amine group functionalized silver-loaded glass antibacterial agent in step S3 in Example 3 with a common silver-loaded glass antibacterial agent; the rest is the same as step S3 in Example 3;

[0057] S3, replacing the tertiary amine group functionalized silver-loaded glass antibacterial master batch in step S4 in Example 3 with the antibacterial master batch prepared in step S2 in this comparative example; the rest is the same as step S4 in Example 3.

[0058] Comparative Example 2

[0059] This comparative example provides another method for preparing a filter core shell, comprising the following steps:

[0060] S1, same as step S1 in Example 2;

[0061] S2, same as step S2 in example 2;

[0062] S3, in the tertiary amine group functionalized silver-loaded glass antibacterial masterbatch, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial agent is 14%; the rest is the same as step S3 in example 2;

[0063] S4, in the filter core shell, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial masterbatch is 2.5%; the rest is the same as step S4 in example 2.

[0064] Comparative example 3

[0065] This comparative example provides another method for preparing a filter core shell, the steps comprising:

[0066] S1, same as step S1 in example 2;

[0067] S2, same as step S2 in example 2;

[0068] S3, in the tertiary amine group functionalized silver-loaded glass antibacterial masterbatch, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial agent is 13%; the rest is the same as step S3 in example 2;

[0069] S4, in the filter core shell, the mass fraction of the tertiary amine group functionalized silver-loaded glass antibacterial masterbatch is 6%; the rest is the same as step S4 in example 2.

[0070] Comparative example 4

[0071] This comparative example provides another method for preparing a filter core shell, the steps comprising:

[0072] Mixing polyethylene and polypropylene, injecting into an injection molding machine to obtain the filter core shell.

[0073] Detection example

[0074] The filter core shells prepared by the preparation methods described in examples 2-3 and comparative examples 1-4 are detected for performance, and the results are shown in tables 1-3;

[0075] Table 1

[0076]

[0077] Table 2

[0078]

[0079] Table 3

[0080]

[0081] In summary, the tertiary amine group functionalized silver-loaded glass antibacterial agent of the present application achieves high-efficiency bacteriostatic effect through the synergistic effect of silver and tertiary amine group, silver reacts with the sulfhydryl group (-SH) of the cell membrane protein of bacteria and other microorganisms, and silver acts as a catalytic center to induce the production of reactive oxygen species (ROS), which has persistent, efficient and broad-spectrum antibacterial performance, the tertiary amine group can spontaneously present nitrogen (N)-protonation induction, contact and destroy the negatively charged cell wall of bacteria and other microorganisms, and can effectively inhibit the growth and reproduction of bacteria; the filter element shell made of the tertiary amine group functionalized silver-loaded glass antibacterial agent of the present application can prevent the initial adhesion and aggregation of bacteria and other microorganisms, thereby inhibiting the growth and reproduction of bacteria inside and on the surface of the air filter element assembly, and at the same time, the filter element shell of the present application is not prone to discoloration.

[0082] The above merely describes the preferred embodiments of the present application, and is not intended to limit the implementation and protection scope of the present application. It should be realized by those skilled in the art that any equivalent replacement and obvious change made according to the content of the present application should be included in the protection scope of the present application.

Claims

1. A method for preparing a tertiary amine group functionalized silver-loaded glass antibacterial agent, characterized by the steps of The method comprises the following steps: S1, taking boric oxide, silicon dioxide, sodium oxide and silver nitrate by weight parts, mixing and sequentially carrying out melting treatment, cooling treatment and crushing treatment to prepare silver-loaded glass; S2, modifying and activating the silver-loaded glass by using dimethylvinylchlorosilane ethanol aqueous solution to prepare modified and activated silver-loaded glass, adding monomer, initiator and crosslinking agent to carry out free radical polymerization reaction, and carrying out washing and drying treatment to obtain the tertiary amine group functionalized silver-loaded glass antibacterial agent; The monomer comprises diethylamine; the initiator comprises 2,2-azoisobutyronitrile; and the crosslinking agent comprises ethylene glycol dimethacrylate. In step S2, the molar ratio of the modified and activated silver-loaded glass, the monomer, the initiator and the crosslinking agent is (1-3):(6-9):1:(1-3).

2. The production method according to claim 1, characterized by, In step S1, the mass ratio of the boric oxide, the silicon dioxide, the sodium oxide and the silver nitrate is (30-35):(50-55):(5-15):

5.

3. The preparation method according to claim 1, characterized in that, In step S1, the melting treatment comprises the following steps: after the mixed boric oxide, silicon dioxide, sodium oxide and silver nitrate are heated to 1300-1330°C at a heating rate of 3-5°C / min, heat preservation is carried out for 20-40 min.

4. The method of claim 1, wherein, The volume fraction of dimethylvinylchlorosilane in the dimethylvinylchlorosilane ethanol aqueous solution is 1-3%.

5. The preparation method according to claim 1, characterized in that, In step S2, the washing and drying treatment comprises the following steps: after washing is carried out by using deionized water, ethanol and acetone as washing agents in sequence, the reaction product is subjected to drying treatment.

6. A tertiary amine group functionalized silver-loaded glass antibacterial agent prepared by the preparation method in any one of claims 1-5.

7. An air filter cartridge assembly comprising: At least part of the air filter element assembly is made of a tertiary amine group functionalized silver-loaded glass antibacterial material prepared by the preparation method in any one of claims 1-5 or the method in claim 6.

8. The air filter cartridge assembly according to claim 7 wherein, The method comprises the following steps: The filter element housing (1), the filter element cover bottom (2) arranged at the top end inside the filter element housing (1), the filter element filter screen (3) arranged inside the filter element housing (1), and the filter element end cover (4) detachably connected to the bottom end of the filter element housing (1); The filter element housing (1) is made of a mixture of the tertiary amine group functionalized silver-loaded glass antibacterial agent and resin; the middle part of the filter element housing (1) is provided with an air inlet (6) along the radial direction of the filter element housing (1); the cross section of the filter element filter screen (3) is annular, and the first gap is formed between the top end of the inner wall of the filter element housing (1) and the top end of the filter element filter screen (3); and the second gap is formed between the inner wall of the filter element housing (1) and the outer wall of the filter element filter screen (3). The filter core cover bottom (2) has a first part arranged in the first gap, the outer periphery of the first part is provided with a plurality of second parts arranged in the second gap, the middle part of the first part is provided with a third part arranged in the third gap formed by the inner ring of the filter core screen (3); The inner wall bottom end of the filter core shell (1) and the bottom end of the filter core screen (3) form a fourth gap; the filter core end cover (4) has a fourth part arranged in the fourth gap, the outer periphery top end of the fourth part is provided with a plurality of fifth parts arranged in the second gap, the bottom end of the second part and the top end of the fifth part have a fifth gap; the middle part top end of the fourth part is provided with a sixth part arranged in the third gap, the top end of the sixth part and the bottom end of the third part have a sixth gap; the middle part bottom end of the fourth part is provided with a seventh part extending to the outside of the filter core shell (1); the outer wall of the seventh part is sleeved with a sealing ring (5); the middle part of the filter core end cover (4) is provided with an air outlet (7), the air outlet (7) penetrates through the seventh part and the sixth part.

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