Blood cross-circulation system of severed limbs

Abstract

The present invention provides a blood cross-circulation system for severed limbs, which belongs to the technical field of medical systems; it includes a power source, an oxygenation device, a control device, a donor animal, and a severed limb connection device, wherein the severed limb is arranged in the severed limb connection device; the donor animal provides neck venous blood, which cooperates with the power source to drive the blood to flow in the entire system, and the oxygenation device first oxygenates the venous blood into arterial blood, and adjusts the blood flow direction and flow rate through the control device to allow part of the blood to flow directly back into the donor animal, and another part of the blood flows into the severed limb and then flows back into the donor animal and in front of the power source. The blood cross-circulation system for severed limbs provided by the present invention can effectively restore and maintain the blood circulation of the severed limb, avoid tissue hypoxia, necrosis, and even death, and can establish blood circulation between the donor animal and the severed limb, thereby maximally maintaining the vitality of the severed limb, and the use effect is good.

Description

Technical Field

[0001] The invention relates to the technical field of medical systems, and in particular to a blood cross-circulation system for severed limbs. Background Art

[0002] In the medical field, especially in trauma treatment, organ transplantation and surgical treatment, it is often necessary to deal with severed limbs. The severed limb means that the blood circulation between the limb and the rest of the body is cut off, which can lead to tissue hypoxia, necrosis and even death. Therefore, how to effectively restore and maintain the blood circulation of severed limbs is an urgent problem to be solved in the medical community.

[0003] At present, the traditional solution is to directly replant the severed limb during surgery, but this requires strict surgical conditions and the success rate is affected by many factors. In addition, in some special cases, such as prolonged ischemia or severe tissue damage, direct replantation may not be possible. Therefore, new methods are urgently needed to maintain the vitality of severed limbs.

[0004] Therefore, the present application provides a severed limb blood cross-circulation system to solve the above-mentioned technical problems. Summary of the invention

[0005] The technical problem to be solved by the present invention is to provide a blood cross-circulation system for severed limbs to solve the problem in the prior art that the blood circulation of severed limbs is cut off, leading to tissue hypoxia, necrosis and even death.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions:

[0007] A severed limb blood cross-circulation system, comprising a power source, an oxygenation device, a regulating device, a donor animal, and a severed limb connecting device, wherein the severed limb is arranged in the severed limb connecting device;

[0008] The donor animal provides neck venous blood, which cooperates with the power source to drive the blood to flow in the entire system, and the oxygenation device first oxygenates the venous blood into arterial blood, and adjusts the blood flow direction and flow rate through the control device to allow part of the blood to flow directly back into the donor animal, and allow another part of the blood to flow into the severed limb and then flow back into the donor animal and in front of the power source.

[0009] As a further preferred embodiment, the power source includes a power pump, and the pressure of the power pump is greater than the total resistance in the system and less than the safe pressure that the blood in the system can withstand.

[0010] As a further preferred embodiment, the total resistance in the system includes the pipeline resistance in the system, the resistance of the regulating device and the resistance of the oxygenation device.

[0011] As a further preferred embodiment, the factors that determine the safe pressure that the blood can withstand in the system include: the blood properties of the donor animal, the vascular elasticity of the donor animal and the severed limb, and the blood flow rate inside the donor animal and the severed limb.

[0012] As a further preferred embodiment, the oxygenation device is a lung membrane installed behind the output end of the power pump, which is used to oxygenate venous blood into arterial blood to simulate human lung function.

[0013] As a further preferred embodiment, the control device includes a control valve, a flow monitor and a pressure monitor. The control valve is installed after the oxygenation device to control the blood flow direction and opening and closing. The flow monitor is mainly used to monitor the blood flow, and the pressure monitor is used to monitor the pressure of the blood in the system to ensure that the blood can flow normally in the system.

[0014] As a further preferred embodiment, the regulating valve controls the blood flow from the power source to the oxygenation device, and controls the blood flow from the oxygenation device to the severed limb.

[0015] As a further preferred embodiment, the donor animal is a pig to provide blood to maintain the operation of the extracorporeal circulation system, and the severed limb connecting device is used to connect the severed limb to the extracorporeal circulation system to ensure that blood can flow to and supply the severed limb.

[0016] As a further preferred embodiment, the severed limb connection device comprises a chassis for storing physiological saline, a severed limb placement box is fixed on the top of the chassis, a plurality of nozzles are installed on the top of the severed limb placement box, and the nozzles extend into the chassis through pipes and are connected to a pump body.

[0017] As a further preferred embodiment, a placement table is provided on the bottom surface of the severed limb placement box directly below the multiple nozzles, multiple straps are installed on the placement table, and multiple return pipes are also installed on the surface of the placement table, and the return pipes extend into the top of the box.

[0018] Compared with the prior art, the present invention has at least the following beneficial effects:

[0019] 1. The severed limb blood cross-circulation system provided by the present invention can effectively restore and maintain the blood circulation of the severed limbs through a power source, an oxygenation device, a regulating device, a donor animal and a severed limb connection device, thereby avoiding tissue hypoxia, necrosis and even death.

[0020] 2. The solution of the present invention allows part of the blood to flow directly back into the donor animal, and the other part of the blood flows into the severed limb and then flows back into the body of the donor animal, thereby maintaining the vitality of the severed limb to the greatest extent.

[0021] 3. The present invention uses pigs as donor animals, whose blood has high compatibility and can effectively maintain the operation of the extracorporeal circulation system.

[0022] 4. The solution of the present invention can effectively maintain the blood circulation of the severed limb during the operation, thereby improving the success rate of the operation.

[0023] 5. The solution of the present invention can effectively maintain the vitality of the severed limb after the limb is severed, providing a good foundation for subsequent treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The accompanying drawings, which are incorporated herein and constitute a part of the specification, illustrate embodiments of the present disclosure and, together with the description, further serve to explain the principles of the present disclosure and to enable those skilled in the relevant art to make and use the present disclosure.

[0025] Figure 1 This is a schematic diagram of the structure of the blood cross-circulation system of severed limbs;

[0026] Figure 2 A schematic block diagram of a control device in a blood cross-circulation system for severed limbs;

[0027] Figure 3 Advantages of selecting donor animals for blood cross-circulation systems of severed limbs;

[0028] Figure 4 Flow chart of the steps involved in constructing a blood cross-circulation system for an amputated limb;

[0029] Figure 5 A schematic diagram of the structure of a severed limb connection device in a severed limb blood cross-circulation system;

[0030] Figure 6 This is a schematic diagram of the internal structure of the severed limb connection device in the blood cross-circulation system of the severed limb.

[0031] In the figure: 1, chassis; 101, liquid level tube; 2, limb placement box; 201, box door; 3, nozzle; 4, control panel; 5, placement table; 501, strap; 502, return pipe.

[0032] As shown in the figure, in order to clearly implement the structure of the embodiment of the present invention, specific structures and devices are marked in the figure, but this is only for illustrative purposes and is not intended to limit the present invention to the specific structure, device and environment. According to specific needs, ordinary technicians in this field can adjust or modify these devices and environments, and the adjustments or modifications made are still included in the scope of the attached claims. DETAILED DESCRIPTION

[0033] The severed limb blood cross-circulation system provided by the present invention is described in detail below in conjunction with the accompanying drawings and specific embodiments. At the same time, it is explained here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments, and those skilled in the art may also adopt other alternatives to implement some known technologies; and the accompanying drawings are only for more specific description of the embodiments, and are not intended to specifically limit the present invention.

[0034] It should be noted that the references to "one embodiment", "embodiment", "exemplary embodiments", "some embodiments" and the like in the specification indicate that the embodiments described may include specific features, structures or characteristics, but not every embodiment may include the specific features, structures or characteristics. In addition, when a specific feature, structure or characteristic is described in conjunction with an embodiment, it should be within the knowledge of a person skilled in the art to implement such feature, structure or characteristic in conjunction with other embodiments (whether or not explicitly described).

[0035] In general, a term can be understood, at least in part, from its use in context. For example, depending, at least in part, on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in the singular sense, or can be used to describe a combination of features, structures, or characteristics in the plural sense. Additionally, the term "based on" can be understood as not necessarily intended to convey an exclusive set of factors, but can instead, depending, at least in part, on the context, allow for the presence of other factors that are not necessarily explicitly described.

[0036] It will be understood that the meaning of “on,” “over,” and “above” in this disclosure should be interpreted in the broadest manner, so that “on” means not only “directly on” something, but also includes the meaning of being “on” something with intervening features or layers therebetween, and “on” or “over” means not only “on” or “above” something, but also includes the meaning of being “on” or “above” something with no intervening features or layers therebetween.

[0037] Additionally, spatially relative terms such as "under," "beneath," "lower," "above," "upper," and the like may be used herein for descriptive convenience to describe the relationship of one element or feature to another element or features, as shown in the accompanying drawings. Spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially relative descriptors used herein may be similarly interpreted accordingly.

[0038] like Figure 1 As shown, an embodiment of the present invention provides a severed limb blood cross-circulation system, comprising a power source, an oxygenation device, a regulating device, a donor animal, and a severed limb connecting device, wherein the severed limb is arranged in the severed limb connecting device.

[0039] The donor animal provides neck venous blood, which cooperates with the power source to drive the blood to flow in the entire system, and the oxygenation device first oxygenates the venous blood into arterial blood, and adjusts the blood flow direction and flow rate through the control device to allow most of the blood to flow directly back into the donor animal, and another small part of the blood to flow into the severed limb and then flow back to the donor animal and in front of the power source.

[0040] Among them, the power source includes a power pump, and the pressure range provided by the power pump is set specifically according to the application scenario and requirements. In the present severed limb blood cross-circulation system, the pressure of the power pump should be large enough to drive the blood to flow through the entire system, but not too large to avoid causing excessive pressure on the blood, leading to blood vessel rupture or other complications, that is, the pressure of the power pump is greater than the total resistance in the system and less than the safe pressure that the blood in the system can withstand.

[0041] In a specific implementation, the total resistance in the system includes the resistance of the pipeline in the system, the resistance of the regulating device and the resistance of the oxygenation device, and the factors in the system that determine the safe pressure that the blood can withstand include: the blood properties of the donor animal, the vascular elasticity of the donor animal and the severed limb, and the blood flow velocity inside the donor animal and the severed limb.

[0042] The oxygenation device is a lung membrane installed behind the output end of the power pump, which is used to oxygenate venous blood into arterial blood to simulate the function of human lungs. Specifically, the membrane lung is usually made of one or more layers of semipermeable membranes, which allow oxygen and carbon dioxide to pass through, but not blood cells and other macromolecules. When blood flows through the membrane lung, oxygen will pass through the semipermeable membrane from the oxygen-rich gas into the blood. At the same time, the carbon dioxide in the blood will also be discharged from the blood through the semipermeable membrane. The blood can be mixed with the oxygen-rich gas through the semipermeable membrane to achieve blood oxygenation. At the same time, in the specific implementation, the membrane lung also needs to take into account the flow rate and pressure of the blood to ensure that the blood can flow smoothly through the membrane lung and achieve an effective oxygenation effect.

[0043] like Figure 2 As shown, the control device includes a control valve, a flow monitor and a pressure monitor.

[0044] The regulating valve is installed behind the oxygenation device and is used to control the blood flow direction and opening and closing. Specifically, the regulating valve controls the blood flow from the power source to the oxygenation device, and controls the blood flow from the oxygenation device to the severed limb.

[0045] The flow monitor is mainly used to monitor the flow of blood to ensure that the blood can flow normally in the system, and can monitor the flow of blood in real time. If an abnormal situation is found, an alarm can be issued in time for timely processing.

[0046] The pressure monitor is mainly used to monitor and control the pressure in the blood circulation system to ensure that the blood can flow smoothly in the system.

[0047] like Figure 3 As shown, the donor animal is a pig, which provides blood to maintain the operation of the extracorporeal circulation system. In addition, the present invention uses pigs as donor animals for human body amputation, which has significant advantages such as physiological similarity, easy acquisition, and economic benefits.

[0048] The severed limb connection device is used to connect the severed limb to an extracorporeal circulation system to ensure that blood can flow to and supply the severed limb.

[0049] like Figure 5 and Figure 6As shown, the severed limb connection device includes a chassis 1 for storing physiological saline, a severed limb placement box 2 is fixed on the top of the chassis 1, openings are provided on both sides of the severed limb placement box 2, and a box door 201 is installed, a plurality of nozzles 3 are installed on the top of the severed limb placement box 2, and the nozzles 3 extend into the chassis 1 through pipes and are connected to a pump body 301, and a control panel 4 is installed on the upper end surface of the severed limb placement box 2, which can be used to control the pump body 301 to extract the physiological saline in the chassis 1, so as to spray the physiological saline on the severed limb placed in the severed limb placement box 2, thereby facilitating further ensuring the vitality of the severed limb.

[0050] At the same time, a placement table 5 is arranged on the bottom surface of the severed limb placement box 2 just below the multiple nozzles 3, and multiple straps 501 are installed on the placement table 5. Multiple return pipes 502 are also installed on the surface of the placement table 5, and the return pipes 502 extend into the top of the chassis 1.

[0051] In specific implementation, a liquid level tube 101 is provided on the side of the chassis 1, a liquid inlet is provided at the top of the liquid level tube 101, and a sealing plug is provided. A roller and a water outlet are also provided on the bottom side of the chassis 1, and a sealing plug is also provided at the water outlet.

[0052] Among them, in this embodiment, the severed limb connection device also includes components such as a vascular cannula, a tourniquet, a connecting pipe and a fixing device. These components work together to connect the blood vessels of the severed limb to the system to form a closed circulatory system.

[0053] In addition, for the construction of the above system, Figure 4 The specific steps are as follows:

[0054] S1. Material preparation: Ensure that all necessary materials are complete and functioning properly, including the pig, power pump, membrane lung (oxygenator), control valve, severed limb, two flow monitors and two pressure monitors.

[0055] S2. System layout: The membrane lung is placed behind the power pump to receive the blood pushed by the power pump and perform oxygenation processing.

[0056] S3. Connect the pipeline: Use appropriate pipeline to connect the pig's internal jugular vein to the power pump to ensure that blood can flow smoothly from the internal jugular vein to the power pump.

[0057] S4. Install the membrane lung: The membrane lung should be placed after the power pump and connected to the power pump outlet to oxygenate the blood.

[0058] S5. Set up a regulating valve: Install a regulating valve on the arterial blood route after membrane lung oxygenation to control the ratio of blood returning to the pig's body and flowing to the severed limb.

[0059] S6. Connect the severed limb: Connect part of the output of the regulating valve to the severed limb artery to provide oxygenated blood to the severed limb.

[0060] S7. Venous return of severed limbs: Ensure that the blood in the severed limb veins can flow back to the pig’s internal jugular vein to form a closed loop.

[0061] S8. Monitoring system: A flow monitor and a pressure monitor are installed in the system to monitor blood flow and pressure respectively to ensure stable operation of the system.

[0062] S9. Debugging and testing: After the system is assembled, debugging is performed to ensure that all components are working properly, and actual testing is performed to verify whether the system can effectively maintain the vitality of the severed limb.

[0063] S10. Continuous monitoring: During system operation, blood flow and pressure are continuously monitored, and control valves are adjusted in time to adapt to the physiological changes of pigs and ensure blood supply to severed limbs.

[0064] Therefore, through the above steps, an effective blood cross-circulation system for severed limbs can be constructed to provide necessary blood circulation for the severed limbs during surgery and maintain the vitality and function of the tissues.

[0065] In summary, the severed limb blood cross-circulation system provided by the present invention can effectively restore and maintain the blood circulation of the severed limb, avoiding tissue hypoxia, necrosis and even death. This system can allow part of the blood to flow directly back into the donor animal, and the other part of the blood flows into the severed limb and then flows back into the donor animal, thereby maintaining the vitality of the severed limb to the maximum extent. This system uses pigs as donor animals, and their blood has high compatibility and can effectively maintain the operation of the extracorporeal circulation system. This system can effectively maintain the blood circulation of the severed limb when the limb is severed during surgery, thereby improving the success rate of the operation. This system can effectively maintain the vitality of the severed limb after the limb is severed, providing a good foundation for subsequent treatment.

[0066] The present invention covers any substitution, modification, equivalent method and scheme made on the essence and scope of the present invention. In order to make the public have a thorough understanding of the present invention, specific details are described in detail in the following preferred embodiments of the present invention, but those skilled in the art can fully understand the present invention without the description of these details. In addition, in order to avoid unnecessary confusion about the essence of the present invention, well-known methods, processes, procedures, components and circuits are not described in detail.

[0067] A person skilled in the art will appreciate that all or part of the steps in the above-mentioned embodiment method can be completed by instructing related hardware through a program, and the program can be stored in a computer-readable storage medium, such as ROM / RAM, a disk, an optical disk, etc.

[0068] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A blood cross-circulation system for severed limbs, characterized in that: It comprises a power source, an oxygenation device, a regulating device, a donor animal and a severed limb connecting device, wherein the severed limb is arranged in the severed limb connecting device; The donor animal provides neck venous blood, which cooperates with the power source to drive the blood to flow in the entire system, and the oxygenation device first oxygenates the venous blood into arterial blood, and adjusts the blood flow direction and flow rate through the control device to allow part of the blood to flow directly back into the donor animal, and allow another part of the blood to flow into the severed limb and then flow back into the donor animal and in front of the power source.

2. The severed limb blood cross-circulation system according to claim 1, characterized in that: The power source comprises a power pump, and the pressure of the power pump is greater than the total resistance in the system and less than the safe pressure that the blood in the system can withstand.

3. The severed limb blood cross-circulation system according to claim 2, characterized in that: The total resistance in the system includes the pipeline resistance in the system, the resistance of the regulating device and the resistance of the oxygenation device.

4. The severed limb blood cross-circulation system according to claim 2, characterized in that: The factors that determine the safe pressure that the blood can withstand in the system include: the blood properties of the donor animal, the elasticity of the blood vessels of the donor animal and the severed limb, and the blood flow rate inside the donor animal and the severed limb.

5. The severed limb blood cross-circulation system according to claim 2, characterized in that: The oxygenation device is a lung membrane installed behind the output end of the power pump, which is used to oxygenate venous blood into arterial blood to simulate the human lung function.

6. The severed limb blood cross-circulation system according to claim 1, characterized in that: The control device includes a control valve, a flow monitor and a pressure monitor. The control valve is installed behind the oxygenation device to control the blood flow direction and opening and closing. The flow monitor is mainly used to monitor the blood flow, and the pressure monitor is used to monitor the pressure of the blood in the system to ensure that the blood can flow normally in the system.

7. The severed limb blood cross-circulation system according to claim 6, characterized in that: The regulating valve controls blood flow from the power source to the oxygenation device and controls blood flow from the oxygenation device to the severed limb.

8. The severed limb blood cross-circulation system according to claim 1, characterized in that: The donor animal is a pig, which provides blood to maintain the operation of the extracorporeal circulation system, and the severed limb connecting device is used to connect the severed limb with the extracorporeal circulation system to ensure that blood can flow to and supply the severed limb.

9. The severed limb blood cross-circulation system according to claim 1, characterized in that: The severed limb connection device comprises a chassis for storing physiological saline, a severed limb placement box is fixed on the top of the chassis, a plurality of nozzles are installed on the top of the severed limb placement box, and the nozzles extend into the chassis through pipelines and are connected to a pump body.

10. The severed limb blood cross-circulation system according to claim 9, characterized in that: A placement table is arranged on the bottom surface of the severed limb placement box, corresponding to the position directly below the plurality of nozzles. A plurality of straps are installed on the placement table, and a plurality of return pipes are also installed on the surface of the placement table. The return pipes extend into the top of the box.

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