Ion transport device adjustment method, system, device, and controller

Abstract

The present application relates to a method, system, device, and controller for adjusting an ion transmission device. The method includes: obtaining an ion beam imaging image; the ion beam imaging image refers to an image formed on a fluorescent screen by incident ions under the influence of input electrical parameters of the ion transmission device; iteratively determining a target fitness value based on the ion beam imaging image, adjusting the input electrical parameters of the ion transmission device according to the target fitness value, and obtaining an ion beam imaging image generated under the influence of the adjusted input electrical parameters until an end condition is met; the target fitness value is used to characterize the degree of correlation between the actual imaging area and the target imaging area of ​​the ion beam imaging image; adjusting the input electrical parameters of the ion transmission device to target electrical parameters, where the target electrical parameters are the electrical parameters of the ion beam imaging image corresponding to the maximum target fitness value, thereby improving the transmission efficiency and focusing effect of the ion transmission device.

Description

Technical Field

[0001] The present application relates to the technical field of ion transmission device adjustment, and in particular to an ion transmission device adjustment method, system, device, and controller. Background Art

[0002] With the development of the field of ion detection, mass spectrometers play a key role in ion detection. How to improve the transmission efficiency and focusing degree of the ion transmission device in the mass spectrometer is the key to improving the detection resolution of the mass spectrometer.

[0003] To address the above issues, SIMION (ion optical problem simulation software) simulation is currently used to adjust the electrical parameters of the ion transmission device. However, since this technology obtains the ion motion trajectory through simulation software, it cannot intuitively and quickly reflect the ion transmission trajectory and focusing degree. Moreover, the simulation results cannot reflect the actual movement of the ions, resulting in poor transmission efficiency and focusing degree of the ion transmission device. Summary of the Invention

[0004] Based on this, it is necessary to provide an ion transmission device adjustment method, system, device, and controller that can improve the transmission efficiency and focusing degree of the ion transmission device in order to address the above technical problems.

[0005] In a first aspect, a method for adjusting an ion transmission device is provided, the method comprising:

[0006] Acquire an ion beam imaging image; the ion beam imaging image refers to an image formed on a fluorescent screen by incident ions under the action of input electrical parameters of an ion transmission device;

[0007] Iteratively executing the process of determining a target fitness value based on the ion beam imaging image, adjusting the input electrical parameters of the ion transmission device based on the target fitness value, and obtaining an ion beam imaging image generated based on the adjusted input electrical parameters until an end condition is satisfied; the target fitness value is used to characterize the degree of correlation between the actual imaging area and the target imaging area of ​​the ion beam imaging image;

[0008] The input electrical parameter of the ion transmission device is adjusted to be the target electrical parameter, and the target electrical parameter is the input electrical parameter of the ion beam imaging image corresponding to the maximum target adaptation value.

[0009] In one embodiment, the target imaging region includes a first target region and a second target region, and the second target region is located within the first target region; and determining the target adaptation value according to the ion beam imaging image includes:

[0010] determining a first adaptation value based on the number of ions located in the first target area;

[0011] When the first fitness value is greater than the first preset threshold, a target fitness value is determined according to the number of ions located in the second target area.

[0012] In one embodiment, the ion beam imaging image includes a first ion beam imaging image and a second ion beam imaging image, the first ion beam imaging image is an image of the ion beam exit position in the transmission region of the ion transmission device, and the second ion beam imaging image is an image of the ion beam exit position in the modulation region of the ion transmission device. Determining the target adaptation value based on the ion beam imaging image includes:

[0013] determining a second adaptation value according to the first ion beam imaging image;

[0014] determining a third adaptation value according to the second ion beam imaging image;

[0015] When the third fitness value is greater than or equal to the second fitness value, the third fitness value is selected as the target fitness value.

[0016] In one embodiment, the target imaging area of ​​the modulation region of the ion transmission device includes a first target area and a second target area, and the second target area is located within the first target area; and determining the third adaptation value based on the second ion beam imaging image includes:

[0017] determining a fourth adaptation value based on the number of ions located in the first target area;

[0018] When the fourth fitness value is greater than the second preset threshold, a third fitness value is determined according to the number of ions located in the second target area.

[0019] In one embodiment, the method further includes:

[0020] When the third fitness value is smaller than the second fitness value, the process proceeds to the step of acquiring an ion beam imaging image.

[0021] In a second aspect, an ion transport device adjustment system is provided, the system comprising:

[0022] An ion transmission device, which is used to form an ion beam imaging image on a fluorescent screen under the action of input electrical parameters;

[0023] A controller is connected to the ion transmission device and is used to execute the steps of the above-mentioned ion transmission device adjustment method.

[0024] In one embodiment, the ion transport device adjustment system further comprises:

[0025] The camera device is arranged on the back side of the fluorescent screen for receiving incident ions, and is used to obtain ion beam imaging images.

[0026] In one embodiment, the ion transport device further comprises:

[0027] A movable device is mechanically connected to the fluorescent screen, and is used to drive the fluorescent screen to move to the ion beam exit position of the ion transmission area of ​​the ion transmission device and the ion beam exit position of the ion transmission area of ​​the ion transmission device at different times to obtain an ion beam imaging image;

[0028] Among them, the ion beam imaging image includes a first ion beam imaging image and a second ion beam imaging image. The first ion beam imaging image is an image of the ion beam emission position in the transmission area of ​​the ion transmission device, and the second ion beam imaging image is an image of the ion beam emission position in the modulation area of ​​the ion transmission device.

[0029] In one embodiment, the ion transport device comprises:

[0030] Radio frequency quadrupole, which is used to receive the incident ion beam;

[0031] Electrostatic quadrupole: The electrostatic quadrupole is placed behind the ion ejection position of the radio frequency quadrupole and is used to adjust the direction of ion beam transmission;

[0032] One-dimensional lens: The one-dimensional lens is placed after the ion exit position of the electrostatic quadrupole and is used to adjust the ion beam transmission direction;

[0033] A modulation accelerator is located after the ion emission position of the one-dimensional lens and is used to adjust the transmission speed of the ion beam;

[0034] The fluorescent screen is placed behind the ion exit position of the one-dimensional lens. The fluorescent screen is used to receive the ion beam and form an ion beam imaging image.

[0035] In a third aspect, an ion transmission device adjustment device is provided, the device comprising:

[0036] An image acquisition module is used to acquire an ion beam imaging image; an ion beam imaging image refers to an image formed on a fluorescent screen by incident ions under the action of input electrical parameters of an ion transmission device;

[0037] a target fitness value determination module, configured to iteratively determine a target fitness value based on the ion beam imaging image, adjust the input electrical parameters of the ion transmission device based on the target fitness value, and obtain an ion beam imaging image generated based on the adjusted input electrical parameters until an end condition is satisfied; the target fitness value is used to characterize the degree of correlation between the actual imaging area and the target imaging area of ​​the ion beam imaging image;

[0038] The regulating module is used to regulate the input electrical parameter of the ion transmission device to the target electrical parameter, where the target electrical parameter is the input electrical parameter of the ion beam imaging image corresponding to the maximum target adaptation value.

[0039] In a fourth aspect, a controller is provided, comprising a memory and a processor, wherein the memory stores a computer program, and the processor implements the steps of the above-mentioned ion transmission device adjustment method when executing the computer program.

[0040] This application has at least the following beneficial effects:

[0041] The above-described ion transmission device adjustment method, system, device, and controller obtain ion beam imaging images formed when different electrical parameters are input to the ion transmission device, and determine a target fitness value reflecting the degree of correlation between the actual imaging area and the target imaging area based on the ion beam imaging image to understand the transmission efficiency and focusing effect of the ion beam. The input electrical parameters of the ion transmission device are adjusted based on the transmission efficiency and focusing effect reflected by the target fitness value, and an ion beam imaging image of the ion transmission device under the influence of the adjusted input electrical parameters is obtained. The above process is repeated until an end condition is satisfied. The electrical parameters of the ion beam imaging image corresponding to the maximum target fitness value are then selected from the multiple target fitness values ​​obtained as the target electrical parameters, and the input electrical parameters of the ion transmission device are adjusted to the target electrical parameters, thereby improving the transmission efficiency and focusing effect of the ion transmission device. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] Figure 1 A diagram showing an application environment of an ion transmission device adjustment method according to an embodiment;

[0043] Figure 2 Schematic diagram of a flow chart of a method for adjusting an ion transport device in one embodiment;

[0044] Figure 3a is a schematic diagram of an ion beam imaging image in one embodiment;

[0045] Figure 3b A schematic diagram of an ion beam imaging image in another embodiment;

[0046] Figure 4 is a schematic flow chart of a method for adjusting an ion transport device in another embodiment;

[0047] Figure 5 Schematic diagram of a flow chart of a method for adjusting an ion transport device in another embodiment;

[0048] Figure 6 A schematic flow chart of a method for adjusting an ion transmission device in yet another embodiment;

[0049] Figure 7A schematic structural diagram of an ion transport device adjustment system according to an embodiment;

[0050] Figure 8 is a schematic structural diagram of an ion transmission device in one embodiment;

[0051] Figure 9 is a structural block diagram of an ion transport device adjustment device in one embodiment;

[0052] Figure 10 FIG. 4 is a diagram showing the internal structure of a controller in one embodiment. DETAILED DESCRIPTION

[0053] In order to make the purpose, technical solutions and advantages of this application more clear, the following further describes this application in detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain this application and are not intended to limit this application.

[0054] The ion transmission device adjustment method provided in the embodiment of the present application can be applied to Figure 1 In the application environment shown, the ion transmission device 102 communicates with the controller 104. The controller 104 can obtain the ion beam imaging image output by the ion transmission device 102; the ion beam imaging image refers to the image of the incident ions formed on the fluorescent screen under the action of the input electrical parameters of the ion transmission device 102; then, iteratively executing the target fitness value based on the ion beam imaging image, adjusting the input electrical parameters of the ion transmission device 102 according to the target fitness value, and obtaining the ion beam imaging image generated under the action of the adjusted input electrical parameters until the end condition is met; the target fitness value is used to represent the degree of correlation between the actual imaging area and the target imaging area of ​​the ion beam imaging image; the controller 104 adjusts the input electrical parameters of the ion transmission device 102 to the target electrical parameters, which are the input electrical parameters of the ion beam imaging image corresponding to the maximum target fitness value. By adjusting the input electrical parameters with the highest degree of correlation between the actual imaging area and the target imaging area as the updated electrical parameters, the updated electrical parameters are applied to subsequent ion transmission control, and online adjustment is performed, thereby improving the ion focusing degree while ensuring transmission efficiency.

[0055] In one embodiment, Figure 2 As shown, a method for adjusting an ion transmission device is provided, which is applied to Figure 1 The controller in the example is used to illustrate the following steps:

[0056] S202, acquiring an ion beam imaging image; the ion beam imaging image refers to an image formed on a fluorescent screen by incident ions under the action of input electrical parameters of an ion transmission device.

[0057] Among them, the electrical parameters can refer to the input voltages required by the various components in the ion transmission device, that is, they can refer to the combination parameters composed of different input voltages; the electrical parameters can also refer to the combination composed of input parameters of different dimensions, such as the combination composed of the voltage, current, inductance and other parameters of the devices in the ion transmission device. For each set of different electrical parameter inputs, after the ion beam passes through the ion transmission device, an ion beam imaging image corresponding to its input electrical parameters will be formed on the fluorescent screen. For example, under the action of a certain input electrical parameter, an ion beam imaging image corresponding to the input electrical parameter will be formed on the fluorescent screen. Figure 3a The ion beam imaging image shown in FIG. 1 is shown in FIG. 2 ; and under the action of another input electrical parameter, the image shown in FIG. 2 is formed on the fluorescent screen. Figure 3b The ion beam imaging image shown is shown. The input electrical parameters can refer to randomly initialized electrical parameters or electrical parameters after iterative update.

[0058] S204, iteratively executes the target fitness value based on the ion beam imaging image, adjusts the input electrical parameters of the ion transmission device according to the target fitness value, and obtains the ion beam imaging image generated under the action of the adjusted input electrical parameters until the end condition is met; the target fitness value is used to characterize the degree of correlation between the actual imaging area and the target imaging area of ​​the ion beam imaging image.

[0059] The target adaptation value is used to characterize the degree of correlation between the actual imaging area and the target imaging area in the above ion beam imaging image. Specifically, it can refer to the proportion of the actual imaging area in the target area. For example, Figure 3a As shown, the target imaging area refers to the area enclosed by rectangle 302; the actual imaging area refers to the imaging spot of the ion beam on the fluorescent screen, such as area 304 composed of multiple spots; thus, the target fitness value can be obtained based on the proportion of area 304 composed of the imaging spots in the target area 302. Alternatively, the target fitness value can refer to the number of ions in the actual imaging area that fall in the target imaging area. The target fitness value can also refer to the set of distances from the center of each imaging spot in the actual imaging area to the center of the target imaging area. The end condition can refer to reaching a preset number of iterations, where the preset number of iterations can be set according to the actual parameter optimization accuracy requirements.

[0060] Specifically, the target fitness value is determined based on the degree of correlation between the actual imaging area and the target imaging area in the ion beam imaging image corresponding to different electrical parameters, and when the termination condition is not met, the particle swarm algorithm is used to iteratively update the input electrical parameters, and the ion beam imaging image corresponding to the updated electrical parameters is continuously acquired, thereby continuously acquiring the target fitness value under different input electrical parameters until the termination condition is met. It should be noted that the particle swarm algorithm used when updating the input electrical parameters is well known to those skilled in the art and will not be described in detail here. Furthermore, when iteratively updating the parameters, the iterative algorithm parameters can be adjusted according to the adjustable accuracy and adjustable range of the ion transmission device parameters, for example, to adjust the termination condition.

[0061] S206 , adjusting the input electrical parameters of the ion transmission device to target electrical parameters, where the target electrical parameters are electrical parameters of the ion beam imaging image corresponding to the maximum target adaptation value.

[0062] Among them, the maximum target adaptation value determined through the above steps represents that in the ion beam imaging image, the degree of correlation between the actual imaging area and the target imaging area is the greatest, that is, under the action of the electrical parameters corresponding to the maximum target adaptation value, the ion transmission device has the best transmission efficiency and focusing effect on the ion beam.

[0063] In the above embodiment, ion beam imaging images formed when the electrical parameters of the input ion transmission device are different are obtained, and a target fitness value reflecting the degree of correlation between the actual imaging area and the target imaging area is determined based on the ion beam imaging image to understand the transmission efficiency and focusing effect of the ion beam. The input electrical parameters of the ion transmission device are adjusted based on the transmission efficiency and focusing effect reflected by the target fitness value, and an ion beam imaging image of the ion transmission device under the adjusted input electrical parameters is obtained. The above process is repeated until an end condition is met. Then, from the multiple target fitness values ​​obtained, the electrical parameters of the ion beam imaging image corresponding to the maximum target fitness value are selected as the target electrical parameters, and the input electrical parameters of the ion transmission device are adjusted to the target electrical parameters, thereby improving the transmission efficiency and focusing effect of the ion transmission device.

[0064] In one embodiment, Figure 4 As shown, the target imaging area includes a first target area and a second target area, and the second target area is located within the first target area; determining the target adaptation value according to the ion beam imaging image includes:

[0065] S402: Determine a first adaptation value according to the number of ions located in the first target area.

[0066] The first target area may refer to the entire target imaging area, and the second target area may refer to a smaller area within the first target area. In a specific embodiment, the second target area may refer to an area with the center of the first target area as the center and the radius of the ion imaging spot as the radius. The meaning represented by the first fitness value is the same as the meaning represented by the above-mentioned target fitness value, but the corresponding area is the first target area, which will not be repeated here.

[0067] Specifically, as described in the above embodiment, the target adaptation value may refer to the number of ions in the actual imaging area that fall in the target imaging area. By comparing the number of ions in the target imaging area with the number of ions initially input into the ion transmission device, and obtaining a first adaptation value based on the comparison result, the transmission efficiency of the ion transmission device under the input parameters can be intuitively known.

[0068] S404 : When the first fitness value is greater than the first preset threshold, determine a target fitness value according to the number of ions located in the second target area.

[0069] The first preset threshold is a minimum limit for characterizing the ion transmission efficiency of the ion transmission device. Specifically, if the threshold is less than or equal to the first preset threshold, it indicates that the ion transmission efficiency of the ion transmission device, under the influence of the input electrical parameters, no longer meets the device's operational accuracy requirements. It should be noted that the first preset threshold can be set based on actual accuracy requirements.

[0070] Specifically, when the first fitness value is greater than the first preset threshold, that is, after ensuring that the transmission efficiency of the ion transmission device meets certain requirements, the target fitness value is further determined based on the number of ions in a smaller second target area falling within the first target area, so as to ensure that the determined target fitness value can more accurately reflect the transmission efficiency and focusing degree of the ion transmission device.

[0071] In the above embodiment, a first fitness value is first determined based on the number of ions in a first target region within the target imaging area. If the first fitness value is greater than a first preset threshold, that is, if the transmission efficiency of the ion transmission device is ensured to meet certain requirements, a target fitness value is further determined based on the number of ions in a second target region. This ensures that the determined target fitness value more accurately reflects the transmission efficiency and focusing degree of the ion transmission device.

[0072] In one embodiment, Figure 5As shown, the ion beam imaging image includes a first ion beam imaging image and a second ion beam imaging image. The first ion beam imaging image is an image of the ion beam exit position in the transmission region of the ion transmission device, and the second ion beam imaging image is an image of the ion beam exit position in the modulation region of the ion transmission device. Step S204 of determining the target adaptation value based on the ion beam imaging image includes:

[0073] S502: Determine a second adaptation value according to the first ion beam imaging image.

[0074] S504: Determine a third adaptation value according to the second ion beam imaging image.

[0075] The meanings represented by the second and third fitness values ​​are similar to those of the target fitness value in the above-mentioned embodiment. It should be emphasized that the second fitness value represents the degree of correlation between the actual imaging area and the target imaging area when the ion beam is imaged at the exit position of the transmission area, that is, it reflects the transmission efficiency and focusing degree of the transmission area of ​​the ion transmission device; the third fitness value represents the degree of correlation between the actual imaging area and the target imaging area when the ion beam is imaged at the exit position of the modulation area, that is, it reflects the transmission efficiency and focusing degree of the modulation area of ​​the ion transmission device. Furthermore, the specific implementation methods for determining the second and third fitness values ​​in the above-mentioned steps can also refer to the specific methods for determining the target fitness value in the above-mentioned embodiment, and will not be repeated here.

[0076] S506: When the third fitness value is greater than or equal to the second fitness value, select the third fitness value as the target fitness value.

[0077] Specifically, the second fitness value obtained based on the ion beam exit position of the transmission zone of the ion transmission device is compared with the third fitness value obtained based on the ion beam exit position of the modulation zone of the ion transmission device. When the third fitness value is greater than or equal to the second fitness value, that is, after passing through the modulation zone, the transmission efficiency and focusing degree of the ion beam are increased, and the third fitness value at this time is determined as the target fitness value, so that the determined electrical parameters can better improve the transmission efficiency and focusing degree of the ion transmission device.

[0078] In one embodiment, Figure 6 As shown, the target imaging area of ​​the modulation region of the ion transmission device includes a first target area and a second target area, and the second target area is located within the first target area; determining the third adaptation value according to the second ion beam imaging image includes:

[0079] S602: Determine a fourth adaptation value according to the number of ions located in the first target area.

[0080] S604 : When the fourth fitness value is greater than the second preset threshold, determine a third fitness value according to the number of ions located in the second target area.

[0081] Among them, the meaning represented by the fourth fitness value is similar to the meaning represented by the first fitness value in the above embodiment, and the meaning represented by the second preset threshold is similar to the meaning represented by the first preset threshold in the above embodiment, which will not be repeated here.

[0082] In the above embodiment, the fourth fitness value is determined based on the first target area of ​​the target imaging area of ​​the modulation zone of the ion transmission device, and then the third fitness value is determined when the fourth fitness value is greater than the second preset threshold value, so that the determined third fitness value can better reflect the transmission efficiency and focusing degree of the modulation zone in the ion transmission device.

[0083] In one embodiment, Figure 5 As shown, the above method also includes:

[0084] S508 : When the third fitness value is smaller than the second fitness value, the process proceeds to the step of acquiring an ion beam imaging image.

[0085] When the third fitness value is smaller than the second fitness value, it indicates that the ion beam is in a divergent state after passing through the modulation area of ​​the ion transmission device, that is, the third fitness value at this time is not suitable as the target fitness value. The third fitness value at this time is discarded and the step of acquiring the ion beam imaging image is re-entered to further ensure that the determined target fitness value is more suitable for adjusting the ion transmission device.

[0086] It should be understood that, although the various steps in the flowcharts involved in the various embodiments described above are displayed in sequence according to the instructions of the arrows, these steps are not necessarily executed in sequence in the order indicated by the arrows. Unless otherwise specified herein, there is no strict order restriction on the execution of these steps, and these steps can be executed in other orders. Moreover, at least a portion of the steps in the flowcharts involved in the various embodiments described above can include multiple steps or multiple stages, and these steps or stages are not necessarily executed and completed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily to be carried out in sequence, but can be executed in turn or alternately with other steps or at least a portion of steps or stages in other steps.

[0087] In one embodiment, Figure 1As shown, an ion transport device adjustment system is provided, comprising: an ion transport device 102 and a controller 104. The ion transport device 102 is configured to cause incident ions to form an ion beam imaging image on a fluorescent screen under the influence of input electrical parameters; the controller 104 is connected to the ion transport device 102 and configured to execute the steps of the ion transport device adjustment method of the above embodiment to achieve the corresponding beneficial effects of the above method embodiment.

[0088] In one embodiment, Figure 7 As shown, the ion transport device adjustment system further includes an imaging device 702. The imaging device 702 is disposed on the back side of the fluorescent screen that receives incident ions. The imaging device 702 is used to acquire an ion beam imaging image and transmit the image to the controller 104 to execute the steps of the ion transport device adjustment method in the above embodiment.

[0089] In one embodiment, Figure 8 As shown, the ion transmission device includes a movable device 802. The movable device 802 is mechanically connected to the fluorescent screen, and the movable device 802 is used to drive the fluorescent screen to move to the ion beam exit position of the ion transmission region of the ion transmission device and the ion beam exit position of the ion transmission region of the ion transmission device at different times to obtain ion beam imaging images;

[0090] Among them, the ion beam imaging image includes a first ion beam imaging image and a second ion beam imaging image. The first ion beam imaging image is an image of the ion beam emission position in the transmission area of ​​the ion transmission device, and the second ion beam imaging image is an image of the ion beam emission position in the modulation area of ​​the ion transmission device.

[0091] The movement of the fluorescent screen can be achieved in a variety of ways, such as micro-motor drive, or guide rail, or rod wire conduction. For example, one end of the fluorescent screen is fixedly connected to the connecting member, and the other end of the connecting member is movably connected to the guide rail of the movable device 802, and a micro-motor is provided on the guide rail. Under the control of the controller 104, the micro-motor drives the connecting member to move on the guide rail, and the connecting member drives the fluorescent screen to move, thereby realizing imaging at the ion beam exit position in the transmission area and the ion beam exit position in the modulation area respectively. As described in the above embodiment, for the introduction of adjusting the input electrical parameters of the ion transmission device based on the first ion beam imaging image and the second ion beam imaging image, it can be seen that by performing ion beam imaging images at different positions, the focusing degree can be further improved by adjusting the input electrical parameters. The implementation process described in the above method embodiment will not be repeated here, but those skilled in the art should understand the implementation process of the ion transmission device adjustment system provided in the embodiment of the present application based on the above records.

[0092] In one embodiment, Figure 8As shown, the ion transmission device further includes: a radio frequency quadrupole 804, an electrostatic quadrupole 806, a one-dimensional lens 808, a modulation accelerator 810, and a fluorescent screen 812. The radio frequency quadrupole 804 is used to receive the incident ion beam; the electrostatic quadrupole 806 is placed after the ion exit position of the radio frequency quadrupole 804 and is used to adjust the transmission direction of the ion beam; the one-dimensional lens 808 is placed after the ion exit position of the electrostatic quadrupole 806 and is used to adjust the transmission direction of the ion beam; the modulation accelerator 810 is placed after the ion exit position of the one-dimensional lens 808 and is used to adjust the transmission speed of the ion beam; and the fluorescent screen 812 is placed after the ion exit position of the one-dimensional lens and is used to receive the ion beam and form an ion beam imaging image.

[0093] In one embodiment, Figure 8 As shown, the modulation acceleration device 810 further includes a repeller plate 8102 , which is placed in the modulation region and is used to push ions into the mass analyzer under the action of the pulse voltage.

[0094] The selection of components such as the radio frequency quadrupole 804 in the ion transmission device is not limited here. Figure 8 The specific structure and the spacing distances between different parts given in the specification do not limit the ion transmission device provided in the embodiments of the present application. It should be understood that the ion transmission devices that can realize the above-mentioned ion transmission path are all within the scope of protection of this application.

[0095] Based on the same inventive concept, embodiments of the present application further provide an ion transport device adjustment device for implementing the aforementioned ion transport device adjustment method. The solution provided by this device is similar to the solution described in the aforementioned method. Therefore, the specific limitations of one or more embodiments of the ion transport device adjustment device provided below can be found in the aforementioned limitations of the ion transport device adjustment method and will not be further elaborated here.

[0096] In one embodiment, Figure 9 As shown, an ion transmission device adjustment device is provided, the device comprising:

[0097] The image acquisition module 902 is used to acquire an ion beam imaging image; the ion beam imaging image refers to an image formed on the fluorescent screen by the incident ions under the action of the input electrical parameters of the ion transmission device.

[0098] The target fitness value determination module 904 is used to iteratively determine the target fitness value based on the ion beam imaging image, adjust the input electrical parameters of the ion transmission device based on the target fitness value, and obtain the ion beam imaging image generated under the action of the adjusted input electrical parameters until the end condition is met; the target fitness value is used to characterize the degree of correlation between the actual imaging area of ​​the ion beam imaging image and the target imaging area.

[0099] The adjustment module 906 is used to adjust the input electrical parameters of the ion transmission device to target electrical parameters, where the target electrical parameters are the input electrical parameters of the ion beam imaging image corresponding to the maximum target adaptation value.

[0100] In one embodiment, the target fitness value determination module 904 includes:

[0101] The first fitness value determining unit is configured to determine a first fitness value according to the number of ions located in the first target area.

[0102] The target fitness value determining unit is configured to determine the target fitness value according to the number of ions located in the second target area when the first fitness value is greater than a first preset threshold.

[0103] In one embodiment, the target fitness value determination module 904 further includes:

[0104] The second fitness value determining unit is configured to determine a second fitness value according to the first ion beam imaging image.

[0105] The third fitness value determining unit is configured to determine a third fitness value according to the second ion beam imaging image.

[0106] The target fitness value selecting unit is configured to select the third fitness value as the target fitness value when the third fitness value is greater than or equal to the second fitness value.

[0107] In one embodiment, the third fitness value determining unit includes:

[0108] a fourth fitness value determining unit, configured to determine a fourth fitness value according to the number of ions located in the first target area;

[0109] The third fitness value selecting unit is configured to determine the third fitness value according to the number of ions located in the second target area when the fourth fitness value is greater than the second preset threshold.

[0110] In one embodiment, the target fitness value determination module 904 further includes:

[0111] The failure jump unit is used to enter the step of acquiring an ion beam imaging image when the third fitness value is smaller than the second fitness value.

[0112] Each module in the aforementioned ion transport control device can be implemented in whole or in part through software, hardware, or a combination thereof. Each module can be embedded in or independent of a processor within a controller in hardware form, or can be stored in memory within the controller in software form, allowing the processor to call and execute the corresponding operations of each module.

[0113] In one embodiment, a controller is provided, which includes a processor, a memory, an input / output interface, a communication interface, a display unit and an input device. The processor, the memory and the input / output interface are connected via a system bus, and the communication interface, the display unit and the input device are connected to the system bus via the input / output interface. The processor of the controller is used to provide computing and control capabilities. The memory of the controller includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The input / output interface of the controller is used to exchange information between the processor and an external device. The communication interface of the controller is used to communicate with an external terminal in a wired or wireless manner, and the wireless manner can be achieved through WIFI, a mobile cellular network, NFC (near field communication) or other technologies. When the computer program is executed by the processor, a method for adjusting an ion transmission device is implemented. The display unit of the controller is used to form a visually visible picture, which can be a display screen, a projection device or a virtual reality imaging device. The display screen can be a liquid crystal display screen or an electronic ink display screen, and the input device of the controller can be a touch layer covering the display screen, or a button, trackball or touchpad set on the controller shell, or an external keyboard, touchpad or mouse.

[0114] Those skilled in the art will understand that Figure 10 The structure shown in the figure is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the controller to which the solution of the present application is applied. The specific controller may include more or fewer components than shown in the figure, or combine certain components, or have a different component arrangement.

[0115] In one embodiment, a controller is provided, including a memory and a processor. The memory stores a computer program, and the processor implements the steps in the above method embodiments when executing the computer program.

[0116] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the steps in the above-mentioned method embodiments are implemented.

[0117] In one embodiment, a computer program product is provided, including a computer program, which implements the steps in the above method embodiments when executed by a processor.

[0118] Those skilled in the art will appreciate that all or part of the processes in the above-mentioned embodiment methods can be implemented by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to memory, database or other media used in the embodiments provided in this application may include at least one of non-volatile and volatile memory. Non-volatile memory may include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory may include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM). The database involved in the various embodiments provided herein may include at least one of a relational database and a non-relational database. Non-relational databases may include, but are not limited to, distributed databases based on blockchains. The processor involved in the various embodiments provided herein may be, but are not limited to, a general-purpose processor, a central processing unit, a graphics processing unit, a digital signal processor, a programmable logic unit, a data processing logic unit based on quantum computing, and the like.

[0119] The technical features of the above embodiments can be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0120] The above-described embodiments merely represent several implementation methods of the present application. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the present application. It should be noted that a person of ordinary skill in the art may make various modifications and improvements without departing from the spirit of the present application, and these modifications and improvements fall within the scope of protection of the present application. Therefore, the scope of protection of the present application shall be determined by the appended claims.

Claims

1. A method for adjusting an ion transmission device, characterized in that: The method comprises: Acquire an ion beam imaging image; the ion beam imaging image refers to an image formed on a fluorescent screen by incident ions under the action of input electrical parameters of the ion transmission device; Iteratively determining a target fitness value based on the ion beam imaging image, adjusting an input electrical parameter of the ion transmission device based on the target fitness value, and acquiring an ion beam imaging image generated based on the adjusted input electrical parameter until an end condition is satisfied; the target fitness value is used to characterize a degree of correlation between an actual imaging area and a target imaging area of ​​the ion beam imaging image; The input electrical parameter of the ion transmission device is adjusted to a target electrical parameter, where the target electrical parameter is an input electrical parameter of an ion beam imaging image corresponding to a maximum target adaptation value.

2. The method according to claim 1, characterized in that The target imaging area includes a first target area and a second target area, and the second target area is located within the first target area; and determining the target adaptation value according to the ion beam imaging image includes: determining a first adaptation value based on the number of ions located in the first target area; In a case where the first fitness value is greater than a first preset threshold, the target fitness value is determined according to the number of ions located in the second target area.

3. The method according to claim 1, characterized in that The ion beam imaging image includes a first ion beam imaging image and a second ion beam imaging image, wherein the first ion beam imaging image is an image of an ion beam exit position in a transmission region of the ion transmission device, and the second ion beam imaging image is an image of an ion beam exit position in a modulation region of the ion transmission device. Determining the target adaptation value based on the ion beam imaging images includes: determining a second adaptation value according to the first ion beam imaging image; determining a third adaptation value according to the second ion beam imaging image; When the third fitness value is greater than or equal to the second fitness value, the third fitness value is selected as the target fitness value.

4. The method according to claim 3, characterized in that The target imaging area of ​​the modulation region of the ion transmission device includes a first target area and a second target area, and the second target area is located within the first target area; and determining the third adaptation value according to the second ion beam imaging image includes: determining a fourth adaptation value based on the number of ions located in the first target area; In a case where the fourth fitness value is greater than the second preset threshold, a third fitness value is determined according to the number of ions located in the second target area.

5. The method according to claim 3, characterized in that The method further comprises: When the third fitness value is smaller than the second fitness value, the process proceeds to the step of acquiring the ion beam imaging image.

6. An ion transport device adjustment system, characterized in that: The system comprises: An ion transmission device, wherein the ion transmission device is used to form an ion beam imaging image on the fluorescent screen under the action of input electrical parameters; A controller is connected to the ion transport device and is used to execute the steps of the ion transport device adjustment method according to any one of claims 1 to 5.

7. The ion transport device adjustment system according to claim 6, wherein: Also includes: An imaging device is provided on the back side of the fluorescent screen for receiving incident ions, and is used for acquiring an imaging image of the ion beam.

8. The ion transport device adjustment system according to claim 6, wherein: The ion transmission device comprises: a movable device, the movable device being mechanically connected to the fluorescent screen, and the movable device being used to drive the fluorescent screen to move to the ion beam exit position of the transmission region of the ion transmission device and the ion beam exit position of the modulation region of the ion transmission device at different times, so as to obtain the ion beam imaging image; Among them, the ion beam imaging image includes a first ion beam imaging image and a second ion beam imaging image, the first ion beam imaging image is an image of the ion beam emission position in the transmission area of ​​the ion transmission device, and the second ion beam imaging image is an image of the ion beam emission position in the modulation area of ​​the ion transmission device.

9. The ion transport device adjustment system according to claim 6, wherein: The ion transport device further comprises: a radio frequency quadrupole, wherein the radio frequency quadrupole is used to receive an incident ion beam; An electrostatic quadrupole, the electrostatic quadrupole being placed behind the ion ejection position of the radio frequency quadrupole and being used to adjust the ion beam transmission direction; a one-dimensional lens, the one-dimensional lens being placed behind the ion exit position of the electrostatic quadrupole and being used to adjust the ion beam transmission direction; A modulation acceleration device, the modulation acceleration device is located after the ion exit position of the one-dimensional lens, and the modulation acceleration device is used to adjust the transmission speed of the ion beam; A fluorescent screen is placed behind the ion exit position of the one-dimensional lens, and is used to receive the ion beam and form an imaging image of the ion beam.

10. An ion transmission device adjustment device, characterized in that: The device comprises: An image acquisition module, configured to acquire an ion beam imaging image; the ion beam imaging image refers to an image formed on a fluorescent screen by incident ions under the action of input electrical parameters of the ion transmission device; a target fitness value determination module, configured to iteratively determine a target fitness value based on the ion beam imaging image, adjust an input electrical parameter of the ion transmission device based on the target fitness value, and obtain an ion beam imaging image generated based on the adjusted input electrical parameter, until an end condition is satisfied; the target fitness value is used to characterize a degree of correlation between an actual imaging area and a target imaging area of ​​the ion beam imaging image; The adjustment module is used to adjust the input electrical parameter of the ion transmission device to a target electrical parameter, where the target electrical parameter is the input electrical parameter of the ion beam imaging image corresponding to the maximum target adaptation value.

11. A controller comprising a memory and a processor, wherein the memory stores a computer program, wherein: When the processor executes the computer program, the steps of the method according to any one of claims 1 to 5 are implemented.

Images