A medical device that is easy to implant

Abstract

The present application relates to the field of medical devices, and in particular to a medical device that is easy to implant, comprising an implant and a delivery system, the delivery system comprising a first delivery tube and a second delivery tube, the implant comprising a valve prosthesis and a centering device, the centering device comprising a support portion and a connecting portion movably connected to the support portion, the second delivery tube being provided with a limiting portion detachably connected to the connecting portion; and the centering device being pre-installed between the first delivery tube and the second delivery tube, and during the release of the centering device, at least part of the limiting portion moves relative to the second delivery tube, while the connecting portion can move relative to the limiting portion.

Description

Technical Field

[0001] The present application belongs to the field of medical devices, and specifically relates to a medical device that is easy to implant. Background Art

[0002] With the extension of human life expectancy and the aging of society, aortic valve disease has become an increasingly common valvular disease. Globally, the number of patients with aortic valve disease increased from 42.9 million in 2015 to 46.1 million in 2019. It is estimated that by 2025, the combined number of AS and AR will reach 52 million worldwide, with a compound annual growth rate of 2.0% from 2019 to 2025.

[0003] TAVR involves transcatheter placement of a fully assembled artificial aortic valve into the affected aortic valve via a vascular / cardiac apex approach, functionally replacing the aortic valve and benefiting patients who are not suitable for traditional surgical treatment. However, problems are often encountered during TAVR procedures. For example, when implanting a device with a clamp, the delivery system struggles to ensure that the implant is aligned with the center of the aortic valve, making it difficult to accurately position the clamp and release the implant.

[0004] Patent CN202211085174.3 discloses a valve delivery system that can be stably released and recovered, including: an implant device, a delivery catheter, a release device and a restraint device; the restraint device can move away from and move close to the release device in a restricted manner, and the release device is connected to the delivery catheter; when the implant device is pre-installed, the implant device and the restraint device are detachably connected, and the distal end of the implant device and the restraint device are confined within the release device; the design defect of this scheme is that: although the release problem of the implant device is solved, the centering problem before release is still unavoidable. Since the delivery catheter is close to the blood vessel wall to enter the target position, if a centering device is not provided, it is difficult for the clamp to enter the bottom of the aortic sinus, which may easily lead to surgical failure.

[0005] Therefore, technicians in this field are committed to developing a medical device that is easy to implant, mainly to solve the following problems: first, the implant is difficult to place in the center of the valve, and the clamp is difficult to accurately enter the sinus; second, the centering device scrapes the blood vessel wall and leaves wounds, causing aortic dissection; third, the setting of the centering adjustment device affects the function of other components. Summary of the Invention

[0006] The object of the present invention is to provide a medical device that is easy to implant, so as to solve the problems raised in the above background technology.

[0007] In order to solve the above technical problems, the present application solves them through the following technical solutions: a medical device that is easy to implant, including an implant and a delivery system, the delivery system including a first delivery tube and a second delivery tube, the implant including a valve prosthesis and a centering device, the centering device including a support portion and a connecting portion movably connected to the support portion, the second delivery tube is provided with a limiting portion that is detachably connected to the connecting portion; and the centering device is pre-installed between the first delivery tube and the second delivery tube, and during the release process of the centering device, at least part of the limiting portion moves relative to the second delivery tube, and at the same time, the connecting portion can move relative to the limiting portion.

[0008] In one embodiment, the first delivery tube is an outer sheath tube, and the second delivery tube is a bend adjustment tube, and the bend adjustment tube is used to pass through the aortic arch.

[0009] In one embodiment, the connecting portion includes a first connecting unit and a second connecting unit arranged at both ends of the supporting portion, and the limiting portion includes a first limiting unit and a second limiting unit, the first connecting unit and the first limiting unit form a first joint, and the second connecting unit and the second limiting unit form a second joint.

[0010] In one embodiment, the centering device is a grid-like structure.

[0011] In one embodiment, the first delivery tube is manipulated to move proximally, and the first joint is positioned in the blood vessel before the second joint.

[0012] In one embodiment, the first limiting unit is fixedly connected to the distal end portion of the second delivery tube, and the second limiting unit is slidable along the second delivery tube.

[0013] In one embodiment, the first limiting unit and the second limiting unit are annularly sleeved outside the second delivery pipe.

[0014] In one embodiment, the limiting portion includes a base, a limiting member sleeved outside the base, and an elastic member, and two ends of the elastic member are respectively connected to the base and the limiting member; and the base further includes a locking structure.

[0015] In one embodiment, the elastic member is sleeved outside the base.

[0016] In another embodiment, the limiting unit includes a plurality of elastic members.

[0017] In one embodiment, the connecting portion includes a swinging member and a matching member, wherein the matching member is pre-installed in a restricted space between the locking structure and the limiting member; and the matching member is spherical and can roll in the restricted space.

[0018] In one embodiment, the locking structure is in an arc shape on the axial cross section of the base, and the arc of the locking structure is larger than a quarter circle.

[0019] In one embodiment, the inner wall of the limiting member is also in an arc shape in the axial cross section, and the arc is a quarter circle.

[0020] In another embodiment, the connecting portion and the limiting portion are snap-connected.

[0021] In one embodiment, the conveying system further includes a control member connected to the restriction member; and the elastic member can be compressed under the operation of the control member, and the fitting member is separated from the restriction unit after escaping the restriction space.

[0022] In one embodiment, the centering device further includes an elastic structure connecting the supporting portion and the connecting portion; and after the mating member is separated from the limiting unit, the elastic structure drives the swinging member to move toward the blood vessel wall in order to restore the original state.

[0023] In one embodiment, when the elastic structure is in a natural state, the support portion is substantially cylindrical.

[0024] In one embodiment, the elastic structure is a clip spring.

[0025] In one embodiment, the elastic structure is a spring clamp.

[0026] In one embodiment, the surfaces of the supporting portion and the connecting portion of the centering device are respectively coated.

[0027] In one embodiment, the centering device includes at least a first form, a second form and a third form; wherein, when the centering device is in the first form, the connecting portion and the supporting portion are compressed in the first delivery tube, and the centering device is generally tubular; when the centering device is in the second form, the supporting portion is in close contact with the blood vessel wall, the connecting portion and the supporting portion are at a certain angle, the center line of the second delivery tube coincides with the center line of the supporting portion, and the axial cross-section of the centering device is generally octagonal; when the centering device is in the third form, the centering device is no longer connected to the restricting portion, the connecting portion and the supporting portion are both in contact with the blood vessel wall, and the centering device is generally cylindrical.

[0028] In one embodiment, an anchoring structure is provided on the outer surface of the support portion; and the anchoring structure is in a barb shape.

[0029] In one embodiment, the valve prosthesis includes a stent, a clamp and an artificial valve leaflet; and the centering device is arranged at the proximal end of the valve prosthesis, and when the centering device is in a second form, the second delivery tube is located in the center of the ascending aorta, and the stent is opposite the center of the aortic valve.

[0030] In one embodiment, the delivery system further includes a release tube, an inner core tube, and a withdrawal sheath connected to the distal end of the inner core tube, wherein the release tube is connected to the proximal end of the stent and can release the proximal end of the stent; and operating the release tube to rotate the stent can change the position of the clamp relative to the aortic valve sinus.

[0031] In one embodiment, after the clamp enters the aortic sinus floor, the inner core tube is operated to move distally to release the distal end of the valve prosthesis; then the release tube is operated to release the proximal end of the valve prosthesis to complete the release of the valve prosthesis.

[0032] In one embodiment, after the valve prosthesis is released, the operator operates the control member to separate the fitting member from the restriction portion, thereby completing the implantation of the centering device.

[0033] In one embodiment, the valve prosthesis and the centering device are not connected to each other. The advantage of this design is that the two will not involve each other when subjected to forces in the body.

[0034] In one embodiment, after release, the outer surface of the centering device adheres to the vessel wall at the ascending aorta, which is beneficial to the formation of endothelialization on the outer surface of the centering device.

[0035] In one embodiment, the outer surface of the elastic structure is covered with a film.

[0036] In one embodiment, the centering device is a centrally symmetrical structure in any state.

[0037] Compared with the prior art, the advantages of the present invention are:

[0038] 1. In the prior art, a valve prosthesis with a clamp is used to replace the aortic valve of the heart. It has good stability and good implantation effect. However, since the target position of the clamp is the bottom of the aortic sinus, the surgeon needs to align the valve prosthesis with the valve center first during operation. However, the delivery system that enters along the aortic wall does not have a device for centering, which makes it difficult for the clamp to enter the target position and the failure rate of the operation is high. The technical solution of the present application avoids the above problems. The implant of the present application includes a valve prosthesis and a centering device. The centering device not only solves the centering problem of the valve prosthesis, but also prevents or solves the problem of aortic dissection. The centering device includes a supporting part and a connecting part. The connecting part and the limiting part arranged outside the second delivery tube are in a detachable connection. During the release of the centering device, the supporting part gradually fits against the blood vessel wall, and the connecting part is relative to the limiting part. Rotation, after the supporting part is completely in contact with the blood vessel wall, the two ends of the connecting part are respectively connected to the supporting part and the limiting part, and the second delivery tube is sleeved in the limiting part so that it can be in the center of the centering device, so the valve prosthesis can face the center of the aortic valve, and operating the delivery system to rotate the valve prosthesis can make the clamping part face the bottom of the aortic sinus, so as to realize the function of making the clamping part smoothly enter the target position; on the other hand, after the valve prosthesis is implanted, the centering device will be separated from the delivery system, which can avoid the problem of aortic dissection caused by the scratching of the supporting part and the blood vessel wall, causing the rupture of the blood vessel wall. Or, if the patient already has a dissection problem, the centering device can close the dissection channel after implantation, and solve the aortic dissection problem while replacing the valve leaflet. In summary, the structural design of the centering device is ingenious, the clinical effect is good, the success rate of the operation is improved, and it has great promotion value.

[0039] 2. Different from the prior art, the connecting part includes two connecting units, namely the first connecting unit and the second connecting unit, and the limiting part also includes the first limiting unit and the second limiting unit respectively connected to the first connecting unit and the second connecting unit, thereby forming a first joint and a second joint. During the release process of the centering device, the design of the first joint and the second joint ensures that the connecting part will not restrict the expansion of the supporting part when it is released to a natural state, and the axial length of the connecting unit will also change when it is released. The design of the first joint and the second joint enables the connecting unit to restore its natural state while rotating relative to the limiting part. Therefore, the supporting part and the connecting part in the second form are not compressed. The centering device is a centrally symmetrical form, and the center line of the second conveying pipe arranged in the limiting part coincides with the center line of the centering device.

[0040] 3. Different from the existing technology, the first limiting unit is fixedly connected to the distal end of the second delivery tube, and the second limiting unit can slide along the second delivery tube. The advantage of this design is that the valve prosthesis is located at the distal end of the second delivery tube, and the first limiting unit is fixed at the distal end of the second delivery tube, that is, the first limiting unit is very close to the valve prosthesis. The closer the distance between the two, the better the centering effect; and, the first and second limiting units are both mounted outside the second delivery tube to ensure that the second delivery tube will not shake at will.

[0041] 4. Different from the existing technology, the limiting part includes a base, a limiting part mounted outside the base, and an elastic part. The limiting unit constrains the matching part within the restricted space formed by the locking structure of the limiting part and the base. The matching part can roll within the restricted space to meet the adjustment requirements of the first joint and the second joint. On the other hand, the control part is connected to the limiting part. Operating the limiting part can drive the elastic part to expand and contract, thereby changing the restricted space, releasing the matching part, and completing the implantation of the centering device. It is simple to operate and has complete functions.

[0042] 5. Different from the existing technology, when the centering device is in the first form, the supporting part and the limiting part are both compressed, occupying a small space and not affecting the pipeline layout of the delivery system; when the centering device is in the second form, the axial cross-section of the centering device is generally octagonal, and the supporting part with the anchoring structure is close to the blood vessel wall, the structure is stable, and the centering effect is good; when the centering device is in the third form, the connecting part and the supporting part are both in contact with the blood vessel wall, which can effectively avoid the problem of aortic dissection and will not affect blood flow. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1a and 1b This is a schematic structural diagram of a medical device that is easy to implant according to the present invention.

[0044] Figure 2a and 2b Schematic diagrams of the structures of the centering device of the present invention in the third form and the first form respectively.

[0045] Figure 3 Schematic diagram of the elastic structure of the present invention.

[0046] Figure 4 Schematic diagram of the limiting portion connected to the first connecting unit of the present invention.

[0047] Figure 5 Schematic diagram of the limiting portion connected to the second connecting unit of the present invention.

[0048] Figure 6 It is a schematic diagram of the structure of the centering device after coating.

[0049] Figure 7 Schematic diagram of the structure of the valve prosthesis of the present invention.

[0050] Figures 8a to 8h Schematic diagram of the process of the conveying system of the present invention entering the target position.

[0051] The names of the parts indicated by the numbers in the accompanying drawings are as follows: 1-delivery system, 11-first delivery tube, 12-second delivery tube, 13-control part, 14-release tube, 15-inner core tube, 16-withdrawal sheath, 2-implant, 3-centering device, 31-support part, 311-anchoring structure, 32-connecting part, 321-first connecting unit, 322-second connecting unit, 323-swinging part, 324-matching part, 33-elastic structure, 4-valve prosthesis, 41-stent, 42-clamping part, 43-artificial valve leaflet, 5-limiting part, 51-first limiting unit, 52-second limiting unit, 53-base, 531-locking structure, 54-limiting part, 55-elastic part, 56-limiting space, 6-first joint, 7-second joint. Implementation Method

[0052] The present application is further described in detail below with reference to the accompanying drawings and embodiments.

[0053] In this application, the end closer to the surgical operator is defined as the "proximal end", and the end farther from the surgical operator is defined as the "distal end". Specific embodiments

[0054] like Figure 1a and 1b As shown, during aortic interventional treatment, a medical device that is easy to implant includes an implant 2 and a delivery system 1, wherein the delivery system 1 includes a first delivery tube 11 and a second delivery tube 12, the implant 2 includes a valve prosthesis 4 and a centering device 3, the centering device 3 includes a support portion 31 and a connecting portion 32 movably connected to the support portion 31, and the second delivery tube 12 is provided with a limiting portion 5 that is detachably connected to the connecting portion 32; and the centering device 3 is pre-installed between the first delivery tube 11 and the second delivery tube 12, and during the release process of the centering device 3, at least part of the limiting portion 5 moves relative to the second delivery tube 12, and at the same time, the connecting portion 32 can move relative to the limiting portion 5.

[0055] In this embodiment, the first delivery tube 11 is an outer sheath tube, and the second delivery tube 12 is a bend adjustment tube, which is used to pass through the aortic arch.

[0056] In this embodiment, Figure 1bAs shown, the connecting portion 32 includes a first connecting unit 321 and a second connecting unit 322 arranged at both ends of the supporting portion 31, and the limiting portion 5 includes a first limiting unit 51 and a second limiting unit 52, the first connecting unit 321 and the first limiting unit 51 form a first joint 6, and the second connecting unit 322 and the second limiting unit 52 form a second joint 7.

[0057] In this embodiment, the centering device 3 is a grid structure; and the grid density of the supporting portion 31 is greater than the grid density of the connecting portion 32 .

[0058] In this embodiment, the first delivery tube 11 is operated to move toward the proximal end, and the first joint 6 is placed in the blood vessel before the second joint 7 .

[0059] In this embodiment, the first limiting unit 51 is fixedly connected to the distal end of the second delivery tube 12 , and the second limiting unit 52 can slide along the second delivery tube 12 .

[0060] In this embodiment, the first limiting unit 51 and the second limiting unit 52 are annularly sleeved outside the second delivery pipe 12 .

[0061] In this embodiment, the limiting portion 5 includes a base 53, a limiting member 54 sleeved outside the base 53, and an elastic member 55, the two ends of the elastic member 55 are respectively connected to the base 53 and the limiting member 54; and the base 53 also includes a locking structure 531, such as Figure 1b shown.

[0062] In this embodiment, the elastic member 55 is sleeved outside the base 53 .

[0063] In this embodiment, the connecting portion 32 includes a swinging member 323 and a fitting member 324 . The fitting member 324 is pre-installed in the restricted space 56 between the locking structure 531 and the restricting member 54 . Moreover, the fitting member 324 is spherical and can roll in the restricted space 56 .

[0064] In this embodiment, the locking structure 531 is arc-shaped on the axial section of the base 53, and the arc of the locking structure 531 is larger than a quarter circle; the inner wall of the limiting member 54 is also arc-shaped on the axial section, and its arc is a quarter circle.

[0065] In this embodiment, the conveying system 1 further includes a control member 13, and the control member 13 is connected to the limiting member 54. Figure 5 and Figure 6and, the elastic member 55 can be compressed under the operation of the control member 13, the fitting member 324 is separated from the restriction unit after getting rid of the restriction space 56, as shown Figure 1b shown.

[0066] In this embodiment, the centering device 3 further includes an elastic structure 33 connecting the supporting portion 31 and the connecting portion 32. Figure 1b and, after the fitting member 324 is separated from the limiting unit, the elastic structure 33 drives the swinging member 323 to move toward the blood vessel wall to restore the original state, as shown in FIG. Figure 8f and 8g shown.

[0067] In this embodiment, when the elastic structure 33 is in a natural state, the support portion 31 is substantially cylindrical.

[0068] In this embodiment, the elastic structure 33 is a spring clamp. Figure 3 shown.

[0069] In this embodiment, the surfaces of the support portion 31 and the connection portion 32 of the centering device 3 are respectively coated, such as Figure 6 shown.

[0070] In this embodiment, the centering device 3 includes at least a first form, a second form and a third form; wherein, when the centering device 3 is in the first form, the connecting portion 32 and the supporting portion 31 are compressed in the first delivery tube 11, and the centering device 3 is generally in the shape of a circular tube. Figure 2b As shown; when the centering device 3 is in the second form, the support portion 31 is in close contact with the blood vessel wall, the connecting portion 32 is at a certain angle to the support portion 31, the second delivery tube 12 coincides with the center line of the support portion 31, and the axial cross-section of the centering device 3 is substantially octagonal, as shown in Figures 1 and 8b; when the centering device 3 is in the third form, the centering device 3 is no longer connected to the restriction portion 5, the connecting portion 32 and the support portion 31 are both in contact with the blood vessel wall, and the centering device 3 is substantially cylindrical, as shown Figure 2a and Figure 8g shown.

[0071] In this embodiment, the outer surface of the support portion 31 is provided with an anchoring structure 311; and the anchoring structure 311 is in the shape of a barb, such as Figure 2a shown.

[0072] In this embodiment, the valve prosthesis 4 includes a stent 41, a clamp 42 and an artificial valve leaflet 43. Figure 7and, the centering device 3 is arranged at the proximal end of the valve prosthesis 4. When the centering device 3 is in the second form, the second delivery tube 12 is located at the center of the ascending aorta, and the stent 41 is opposite to the center of the aortic valve.

[0073] In this embodiment, the delivery system 1 further comprises a release tube 14, an inner core tube 15 and a retraction sheath 16 connected to the distal end of the inner core tube 15. The release tube 14 is connected to the proximal end of the stent 41 and can release the proximal end of the stent 41. Figure 1a and, operating the release tube 14 to rotate the stent 41 can change the position of the clamp 42 relative to the aortic valve sinus.

[0074] In this embodiment, after the clamping member 42 enters the aortic sinus bottom, the inner core tube 15 is operated to move distally to release the distal end of the valve prosthesis 4; then the release tube 14 is operated to release the proximal end of the valve prosthesis 4, completing the release of the valve prosthesis 4. Figure 8e shown.

[0075] In this embodiment, after the valve prosthesis 4 is released, the operator operates the control member 13 to separate the fitting member 324 from the restricting portion 5 , thereby completing the implantation of the centering device 3 .

[0076] In this embodiment, the valve prosthesis 4 and the centering device 3 are not connected to each other. The advantage of this design is that after implantation, the two will not be pulled by each other when subjected to forces in the body.

[0077] In this embodiment, after being released, the outer surface of the centering device 3 adheres to the blood vessel wall at the ascending aorta, which is beneficial to the formation of endothelialization on the outer surface of the centering device 3 .

[0078] In this embodiment, the outer surface of the elastic structure 33 is covered with a film.

[0079] In this embodiment, the centering device 3 is a centrosymmetrical structure in any state.

[0080] The exemplary operation process of the conveying system 1 of this embodiment is as follows: Figures 8a to 8h As shown:

[0081] (1) The delivery system 1 enters the aorta through a minimally invasive femoral artery retrograde puncture, and the implant 2 crosses the aortic arch as the delivery system 1 bends and then reaches the ascending aorta, and the valve prosthesis 4 enters the aortic root lesion;

[0082] (2) The first delivery tube 11 is withdrawn to expose the clamping member 42. The first delivery tube 11 is further withdrawn, and the centering device 3 is gradually released to enter the second state. The support portion 31 is in close contact with the blood vessel wall, and the center of the second delivery tube 12 is aligned with the center of the ascending aorta. Figure 2b As shown, Figure 8a and 8b As shown;

[0083] (3) Rotate the release tube 14 so that the clamping members 42 are facing the aortic sinus, as shown in FIG. Figure 8c As shown;

[0084] (4) Operate the delivery system 1 so that the clamp 42 enters the sinus bottom of the aortic valve, as shown in FIG. Figure 8d As shown, the withdrawn sheath 16 is operated to release the distal end of the valve prosthesis 4, and the release tube 14 is operated to release the proximal end of the valve prosthesis 4 to complete the implantation of the valve prosthesis 4. Figure 8e As shown;

[0085] (5) The control member 13 is operated to compress the elastic member 55, the shape of the restricted space 56 is changed, the fitting member 324 is released from the restricted space 56, and the swing member 323 moves to fit the blood vessel wall. Figure 8f As shown, the control member 13 operates the first limiting unit 51 and the second limiting unit 52 in the directions of the arrows shown in the figure, respectively, to complete the implantation of the centering device 3;

[0086] (6) Recover the delivery system 1 and complete the operation, as shown in FIG. Figure 8g and 8h shown.

[0087] The above content is only a preferred embodiment of the present application. For ordinary technicians in this field, according to the concept of the present application, there may be changes in the specific implementation method and application scope. The content of this specification should not be understood as limiting the present application.

Claims

1. A medical device for easy implantation, comprising an implant and a delivery system, wherein the delivery system comprises a first delivery tube and a second delivery tube, characterized in that: The implant includes a valve prosthesis and a centering device, the centering device includes a support portion and a connecting portion movably connected to the support portion, and the second delivery tube is provided with a restricting portion detachably connected to the connecting portion. Moreover, the centering device is pre-installed between the first delivery tube and the second delivery tube. During the release of the centering device, at least part of the limiting portion moves relative to the second delivery tube, and the connecting portion can move relative to the limiting portion. The centering device comprises at least a first form, a second form and a third form. When the centering device is in the first form, the connecting portion and the supporting portion are compressed in the first delivery tube, and the centering device is generally tubular. When the centering device is in the second form, the supporting portion is in close contact with the blood vessel wall, the connecting portion and the supporting portion form a certain angle, the center line of the second delivery tube coincides with the center line of the supporting portion, and the axial cross-section of the centering device is generally octagonal. When the centering device is in the third form, the centering device is no longer connected to the limiting portion, and the connecting portion and the supporting portion both adhere to the blood vessel wall, and the centering device is generally cylindrical.

2. The medical device according to claim 1, wherein: The connecting portion includes a first connecting unit and a second connecting unit provided at both ends of the supporting portion, and the limiting portion includes a first limiting unit and a second limiting unit. The first connecting unit and the first limiting unit form a first joint, and the second connecting unit and the second limiting unit form a second joint.

3. The medical device according to claim 2, wherein: The first limiting unit is fixedly connected to the distal end portion of the second delivery tube, and the second limiting unit is slidable along the second delivery tube.

4. The medical device for easy implantation according to claim 1, characterized in that: The limiting portion includes a base, a limiting member sleeved outside the base, and an elastic member, and two ends of the elastic member are respectively connected to the base and the limiting member; and the base also includes a locking structure.

5. The medical device for easy implantation according to claim 4, characterized in that: The connecting portion includes a swinging member and a matching member. The matching member is pre-installed in a restricted space between the locking structure and the limiting member. Furthermore, the matching member is spherical and can roll in the restricted space.

6. The medical device for easy implantation according to claim 5, characterized in that: The conveying system further includes a control member connected to the restriction member; and the elastic member can be compressed under the operation of the control member, and the matching member is separated from the restriction portion after escaping the restriction space.

7. The medical device for easy implantation according to claim 5 or 6, characterized in that: The centering device further includes an elastic structure connecting the supporting portion and the connecting portion; and after the fitting member is separated from the limiting portion, the elastic structure drives the swinging member to move toward the blood vessel wall in order to restore the original state.

8. The medical device for easy implantation according to claim 1, characterized in that: An anchoring structure is provided on the outer surface of the support portion; and the anchoring structure is in a barb shape.

9. The medical device for easy implantation according to claim 1, characterized in that: The valve prosthesis includes a stent, a clamp and an artificial valve leaflet; and the centering device is arranged at the proximal end of the valve prosthesis. When the centering device is in a second form, the second delivery tube is located in the center of the ascending aorta, and the stent is opposite the center of the aortic valve.

10. The medical device for easy implantation according to claim 9, characterized in that: The delivery system also includes a release tube, an inner core tube and a withdrawal sheath connected to the distal end of the inner core tube, wherein the release tube is connected to the proximal end of the stent and can release the proximal end of the stent; and operating the release tube to rotate the stent can change the position of the clamp relative to the aortic valve sinus.

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