Experimental rat leg fixing device and operation method thereof

Abstract

The invention relates to the technical field of animal medicine experiment auxiliary instruments, in particular to an experimental rat leg fixing device which comprises a base, a lifting mechanism is arranged in the base, a body fixing mechanism is arranged on the lifting mechanism, and a leg fixing mechanism is arranged on the body fixing mechanism. The leg fixing mechanism comprises a thigh fixing part and a shank fixing part; the shank fixing part is detachably connected to the body fixing mechanism and corresponds to the thigh fixing part. The fixing and clamping of rats with different body types are realized through the adjustable body fixing mechanism, the technical effect of separating the thighs of the rats and clamping and fixing the rats without injury is realized through the arrangement of the thigh fixing part, and the shank fixing part is detachably arranged at the position corresponding to the thigh fixing part, so that the rats with different body types can be fixed and clamped. According to the device, the selective independent fixing mode of the rat shanks is achieved, the practicability of the whole device is improved, and the technical problem that in the prior art, in the rat clamping and fixing process, the rat skin is prone to being hurt is solved.

Description

Technical Field

[0001] The invention relates to the technical field of animal medical experiment auxiliary instruments, and in particular to an experimental rat leg fixing device and an operating method thereof. Background Art

[0002] Over the years, mice have been used in many experimental studies. Compared with mice, rats are larger in size, easier to operate, and their physiological characteristics are easy to observe. They have certain adaptability and aggressiveness, and have gradually become an important model animal for studying various human diseases. It is worth noting that 90% of the genes in the rat genome match those of mice and humans. The 2.75 billion base pairs on rat chromosomes are also quite close to the 2.9 billion base pairs on human chromosomes. Almost all known genes related to human diseases can be found in rats, enabling people to better understand the mechanisms related to genetics, diseases, drug effects, etc., which provides great help for the exploration of human diseases.

[0003] Animal experiments refer to scientific research conducted in laboratories using animals in order to gain new knowledge about biology, medicine, etc. or to solve specific problems. Animal experiments must be conducted by or under the guidance of trained personnel with research degrees or professional technical capabilities. The rat fixation device can ensure that the rats maintain a relatively stable position during the experiment, reduce their movement and struggle, and thus reduce the stress response of the rats.

[0004] After searching, the Chinese patent with the authorization announcement number of CN 113171204 B discloses an experimental rat leg fixing device with adjustable angle, including a shell, a support frame is provided at the upper end of the shell, a plurality of fixed structures are provided at the upper end of the support frame, and an operating table is provided above the support frame. In the present invention, the mouse is fixed on the second fixed plate with a binding device, and then one foot of the mouse is placed in the corresponding connection port, and then the locking rope is wound around the take-up wheel by turning the knob. During the process of the locking rope being wound around the take-up wheel, it will continuously approach the ankle of the mouse, thereby fixing the foot of the mouse. By analogy, the other feet of the mouse can be fixed in the corresponding fixed sleeves respectively, and one of the rotation axes is first blocked by one of the limit frames, and then the first electric push rod is opened, and the operating table is supported by the first electric push rod, and the operating table will rotate with the rotation axis blocked by the limit frame as the rotation axis. In this way, the operating table can be adjusted at multiple angles.

[0005] The above-mentioned fixing device can fix the body and limbs of the rat, but the locking rope is used to wrap and fix the rat's limbs, which may cause skin damage to the rat during the struggle, thereby causing inaccurate experimental results or even the death of the rat. Summary of the invention

[0006] The technical problem in the above-mentioned prior art that when fixing the rat's limbs, the rat's limbs are wrapped and fixed by locking ropes, which may cause skin damage to the rat during its struggle, ultimately leading to inaccurate experimental results or even the death of the rat.

[0007] Technical idea: Based on the technical problems of the prior art, the present application provides a rat fixation device for experiments, which realizes the adjustment of the body fixation mechanism through the meshing of gears and racks to make it adapt to rats of different sizes, and realizes the fixation mode of the rat's legs without damage through the leg fixation mechanism, and can selectively fix any one leg of the rat separately.

[0008] To achieve the above object, the technical solution adopted by the present invention is: The present application provides a rat fixing device for experiments, comprising a base, wherein a lifting mechanism is arranged inside the base, a body fixing mechanism is arranged on the lifting mechanism, and a leg fixing mechanism is arranged on the body fixing mechanism.

[0009] Furthermore, the leg fixing mechanism includes a thigh fixing portion and a calf fixing portion; the calf fixing portion is detachably connected to the body fixing mechanism and corresponds to the thigh fixing portion.

[0010] Specifically, the body fixing mechanism includes a first motor, a first gear, a first rack, a support column, a support plate, a support frame and four sets of fixing frames; The first motor is arranged on the lifting mechanism, and the output end of the first motor is connected to the first gear; First racks are symmetrically meshed on both sides of the first gear, and each end of the first rack is fixedly connected to a support column; One end of the support column is slidably connected to the lifting mechanism, and the other end is fixedly connected to the support plate; It should be noted that a limit block is provided at the end of the support column, and the sliding connection of the support column on the lifting mechanism is achieved through the limit block.

[0011] The support plate is a two-half structure and is slidably connected in an offset manner up and down, and a support frame with a two-half structure is correspondingly connected to the support plate; The four groups of fixing frames are arranged on the supporting frame in pairs.

[0012] In detail, an arc-shaped notch is provided on the fixing frame, and the fixing frames are brought together to form a ring structure, which can realize the clamping and fixing of the rat body.

[0013] Furthermore, the body fixing mechanism further comprises a connecting block, a support rod, a second rack, a half gear, a connecting rod, an electric push rod and a fixing rod; Both ends of the support frame are fixedly connected with connection blocks, and the connection blocks are provided with movable grooves; Each of the fixing frames is fixedly connected with a support rod, and the end of the support rod is slidably connected to the connection block through a movable groove; It should be noted that a limit plate is provided at the end of the support rod, and a sliding connection between the support rod and the connecting block is achieved through the limit plate.

[0014] A second rack is disposed at the bottom of each of the fixing frames, and a half gear is meshed on each of the second racks; Each of the half gears is rotatably connected to a connecting rod, and the ends of the two connecting rods are rotatably connected to electric push rods; The electric push rod and the half gear are fixedly connected to the connecting block through a fixing rod.

[0015] In the above technical solution, the thigh fixing part includes a fixing hole, an air pump and an air tube; Each of the fixing frames is provided with a fixing hole, and an air bag is arranged in the fixing hole; One end of the trachea is connected to the air bag, and the other end is connected to the air pump.

[0016] In particular, the calf fixing part includes a fixing sleeve, a second motor, a second gear, a toothed disc, a limiting groove, a limiting column, a movable push rod, a water balloon, a piston cylinder and a hose; One end of the fixing sleeve is detachably connected to any one of the fixing frames via a connecting piece, and the other end is provided with a second motor; The output end of the second motor is connected to a second gear, and the second gear is meshed with a gear disc; The toothed disc is provided with a plurality of limit slots, each of which is provided with a limit column in a sliding manner; Specifically, the limiting groove is an arc-shaped structure.

[0017] The end of the limit column is fixedly connected with a movable push rod, the movable push rod is slidably connected with the fixed sleeve, and the head end of the movable push rod is provided with a plurality of water balloons; It should be noted that the interior of the movable push rod is a hollow structure.

[0018] The fixed sleeve is fixedly connected to a piston cylinder, and the side end of the movable push rod is fixedly connected to the piston rod in the piston cylinder; The head end of the piston cylinder is connected with a hose, and the hose is communicated with the water balloon.

[0019] Specifically, the end of the hose is connected to the movable push rod, and further communicates with the water balloon at the head end of the movable push rod.

[0020] Preferably, the fixed sleeve comprises a first sleeve and a second sleeve, and the first sleeve is slidably connected with the second sleeve.

[0021] Furthermore, the connecting member includes a connecting tube, a pressing block, a spring and a locking block; Connecting tubes are symmetrically arranged on both sides of the first sleeve, and pressing blocks are slidably arranged on both upper and lower sides of the connecting tubes; The end of each pressing block is fixedly connected with a locking block; One end of each of the springs is connected to the inner wall of the connecting tube, and the other end is connected to the locking block; The locking block matches with the locking hole formed on the fixing frame.

[0022] In the above technical solution, the lifting mechanism includes two electric telescopic rods and a fixed disc; One end of each electric telescopic rod is connected to the base, and the other end is connected to the bottom of the fixed disc; The fixed disc is symmetrically provided with two sliding grooves, and the support column is slidably connected with the fixed disc via the sliding grooves.

[0023] An operating method of an experimental rat fixing device comprises the following steps: S1: The body fixing mechanism and the leg fixing mechanism are extended from the base by starting the lifting mechanism; S2: adjusting the body fixing mechanism according to the body size of the rat to fix the body; S3: The rat's limbs are further separated and non-traumatically fixed using a leg fixation mechanism.

[0024] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention drives the two half support plates to move toward each other through the cooperation between the first gear and the first rack, thereby adjusting the distance between the left and right fixing frames; further, through the cooperation between the second rack and the half gear, the distance between the front and rear fixing frames is adjusted, thereby achieving the technical effect of fixing the rat body according to the rat's body shape.

[0025] 2. The present invention achieves separate fixation of the rat's thighs by means of fixing holes opened on four groups of fixing frames, and further provides air bags in the fixing holes and inflates the air bags with an air pump, thereby achieving firm fixation of the rat's thighs and avoiding damage to the rat's legs through the cushioning of the air bags.

[0026] 3. The present invention has a fixing sleeve detachably connected at a position corresponding to the fixing hole, and the movable push rod is moved closer by meshing the second gear with the toothed disc, thereby achieving the technical effect of fixing the rat's calf. Furthermore, the water balloon at the head end of the movable push rod is provided to avoid damage to the rat's calf during fixation and clamping.

[0027] 4. The present invention configures the fixing sleeve as a first sleeve and a second sleeve that are slidably sleeved on each other, so that the fixing sleeve can be adjusted according to the length of the rat's calf, making it suitable for clamping and fixing rats of different sizes.

[0028] 5. The present invention is provided with a lifting mechanism, so that when not in use, the electric telescopic rod can be retracted to drive the entire structure on the fixed disc to be stored into the base, which is convenient for storage and placement. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 It is a three-dimensional diagram of the overall structure of the present invention; Figure 2 For the present invention Figure 1 Middle main view; Figure 3 For the present invention Figure 2 Middle top view; Figure 4 For the present invention Figure 3 Enlarged view of part A in the middle; Figure 5 It is a three-dimensional diagram of the lifting mechanism structure of the present invention; Figure 6 It is a three-dimensional diagram of the structure of the body fixing mechanism of the present invention; Figure 7 For the present invention Figure 6 Middle main view; Figure 8 For the present invention Figure 7 Middle bottom view; Fig. 9 It is a three-dimensional diagram of the structure of the calf fixing part of the present invention; Fig.10 It is a partial structural schematic diagram of the calf fixing part of the present invention; Fig.11 For the present invention Fig.10 Middle top view; Fig.12 For the present invention Fig.11 Section view in the AA direction; Fig.13 It is a three-dimensional diagram of the connecting piece structure of the present invention; Fig.14 For the present invention Fig.13 Middle main view; Fig.15 For the present invention Fig.14 Cross-sectional view in the middle BB direction; In the figure: 1, base; 2, lifting mechanism; 21, electric telescopic rod; 22, fixed disc; 3, body fixing mechanism; 31, first motor; 32, first gear; 33, first rack; 34, support column; 35, support plate; 36, support frame; 37, fixed frame; 38, connecting block; 39, support rod; 310, second rack; 311, half gear; 312, connecting rod; 313, electric push rod; 314, fixed rod; 4, leg fixing mechanism; 41, Thigh fixing part; 411, fixing hole; 412, air pump; 413, air pipe; 42, calf fixing part; 421, fixing sleeve; 422, second motor; 423, second gear; 424, toothed disc; 425, limiting groove; 426, limiting column; 427, movable push rod; 428, water balloon; 429, piston cylinder; 4210, hose; 5, connector; 51, connecting cylinder; 52, pressing block; 53, spring; 54, locking block; 55, locking hole. DETAILED DESCRIPTION

[0031] In order to enable those skilled in the art to better understand the technical solution of the present invention, the technical solution of the present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0032] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "front end", "back end", "inside", "outside", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, they should not be understood as limitations on the present invention.

[0033] In the description of this application, it should also be noted that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0034] The inventors have found that most of the traditional rat leg fixation devices can only fix the rat's body, thereby achieving the purpose of fixing the legs. There is currently no device that can achieve non-traumatic fixation of a single leg. This will cause doctors to waste time when operating on rats, and the injury of the rat will affect the experimental results.

[0035] Based on the above findings, the present application provides an experimental rat fixation device, comprising a base 1 , wherein a lifting mechanism 2 is arranged inside the base 1 , a body fixation mechanism 3 is arranged on the lifting mechanism 2 , and a leg fixation mechanism 4 is arranged on the body fixation mechanism 3 . Example 1

[0036] Reference Figure 1-12 As shown, the present application provides an experimental rat fixation device, comprising a base 1 , wherein a lifting mechanism 2 is arranged inside the base 1 , a body fixation mechanism 3 is arranged on the lifting mechanism 2 , and a leg fixation mechanism 4 is arranged on the body fixation mechanism 3 .

[0037] Specifically, the base 1 is a cylindrical structure with an open upper end and a hollow structure, and the hollow internal space is convenient for storage.

[0038] Furthermore, the lifting mechanism 2 includes two electric telescopic rods 21 and a fixed disc 22; one end of each electric telescopic rod 21 is connected to the base 1, and the other end is connected to the bottom of the fixed disc 22; two sliding grooves are symmetrically opened on the fixed disc 22, and the body fixing mechanism 3 is slidably connected to the fixed disc 22 through the sliding groove.

[0039] Furthermore, the body fixing mechanism 3 includes a first motor 31, a first gear 32, a first rack 33, a support column 34, a support plate 35, a support frame 36 and four sets of fixing frames 37; The first motor 31 is disposed on the fixed disc 22, and the output end of the first motor 31 is connected to a first gear 32; first racks 33 are symmetrically meshed on both sides of the first gear 32, and each end of the first rack 33 is fixedly connected to a support column 34; One end of the support column 34 is slidably connected to a sliding groove provided on the fixed disc 22, and the other end is fixedly connected to a support disc 35; the support disc 35 is a two-half structure and is slidably connected in an offset manner up and down, and a support frame 36 of a two-half structure is correspondingly connected to the support disc 35; the four groups of fixed frames 37 are correspondingly arranged on the support frame 36 in pairs.

[0040] The first gear 32 cooperates with the first rack 33 to drive the two halves of the support plate 35 to move toward each other, thereby adjusting the distance between the left and right fixing frames 37 to achieve the purpose of clamping and fixing the rat body.

[0041] More specifically, the body fixing mechanism 3 further includes a connecting block 38, a supporting rod 39, a second rack 310, a half gear 311, a connecting rod 312, an electric push rod 313 and a fixing rod 314; Both ends of the support frame 36 are fixedly connected to a connecting block 38, and a movable groove is provided on the connecting block 38; each of the fixing frames 37 is fixedly connected to a supporting rod 39, and the end of the supporting rod 39 is slidably connected to the connecting block 38 through a movable groove; A second rack 310 is provided at the bottom of each fixing frame 37, and a half gear 311 is meshed on each of the second racks 310; a connecting rod 312 is rotatably connected to each of the half gears 311, and the ends of the two connecting rods 312 are rotatably connected to electric push rods 313; the electric push rods 313 and the half gears 311 are fixedly connected to the connecting block 38 via a fixing rod 314.

[0042] The electric push rod 313 drives the half gear 311 to mesh with the second rack 310, thereby adjusting the distance between the front and rear fixing frames 37, thereby achieving the technical effect of clamping and fixing the rat body more stably.

[0043] In the above technical solution, the leg fixing mechanism 4 includes a thigh fixing portion 41 and a calf fixing portion 42 ; the calf fixing portion 42 is detachably connected to the body fixing mechanism 3 and corresponds to the thigh fixing portion 41 .

[0044] As an example, the thigh fixing portion 41 includes a fixing hole 411 , an air pump 412 , and an air tube 413 ; A fixing hole 411 is formed through each of the fixing frames 37 , and an air bag is arranged in the fixing hole 411 ; one end of the air pipe 413 is connected to the air bag, and the other end is connected to the air pump 412 .

[0045] The airbag is inflated by the air pump 412 to expand the airbag, thereby achieving the purpose of clamping and fixing the base of the rat's leg. The characteristics of the airbag prevent the rat's leg from being injured during the clamping process. Example 2

[0046] Based on Example 1, refer to Figure 9-12 As shown, in order to achieve the purpose of selectively fixing the rat's calf, a calf fixing portion 42 is detachably connected to the position corresponding to the fixing hole 411 through a connecting member 5 .

[0047] Specifically, the calf fixing part 42 includes a fixing sleeve 421, a second motor 422, a second gear 423, a toothed disc 424, a limiting groove 425, a limiting column 426, a movable push rod 427, a water balloon 428, a piston cylinder 429 and a hose 4210; One end of the fixed sleeve 421 is detachably connected to any of the fixed frames 37 via a connecting member 5, and the other end is provided with a second motor 422; the output end of the second motor 422 is connected to a second gear 423, and the second gear 423 is meshed with a toothed disc 424; The toothed disc 424 is provided with a plurality of limit slots 425, each of which is provided with a limit column 426 in a sliding manner; a movable push rod 427 is fixedly connected to the end of the limit column 426, and the movable push rod 427 is slidably connected to the fixed sleeve 421, and a plurality of water balloons 428 are provided at the head end of the movable push rod 427; The fixed sleeve 421 is fixedly connected to a piston cylinder 429 , and the side end of the movable push rod 427 is fixedly connected to the piston rod in the piston cylinder 429 ; the head end of the piston cylinder 429 is connected to a hose 4210 , and the hose 4210 is connected to the water balloon 428 .

[0048] The meshing of the second gear 423 and the toothed disc 424 enables the movable push rod 427 to move closer, thereby achieving the technical effect of fixing the rat's calf. Furthermore, the provision of the water balloon 428 at the head end of the movable push rod 427 avoids damage to the rat's calf during fixation and clamping. Example 3

[0049] Based on the second embodiment, refer to Figure 13-15 As shown, the connecting member 5 includes a connecting tube 51, a pressing block 52, a spring 53 and a locking block 54; The first sleeve is symmetrically provided with connecting tubes 51 on both sides, and pressing blocks 52 are slidably provided on both sides of the connecting tube 51; each end of the pressing block 52 is fixedly connected with a locking block 54; One end of each spring 53 is connected to the inner wall of the connecting tube 51 , and the other end is connected to a locking block 54 ; the locking block 54 matches with a locking hole 55 provided on the fixing frame 37 .

[0050] By pressing the pressing block 52, the locking block 54 is driven to move closer to each other, so that the spring 53 is stretched, and the locking block 54 is inserted into the locking hole 55, the pressure on the pressing block 52 is released, and under the action of the elastic force of the spring 53, the locking block 54 and the locking hole 55 are locked and fixed. Specific application process:

[0051] Over the years, mice have been used in many experimental studies. Compared with mice, rats are larger in size, easier to operate, and their physiological characteristics are easy to observe. They have certain adaptability and aggressiveness, and have gradually become an important model animal for studying various human diseases. It is worth noting that 90% of the genes in the rat genome match those of mice and humans. The 2.75 billion base pairs on rat chromosomes are also quite close to the 2.9 billion base pairs on human chromosomes. Almost all known genes related to human diseases can be found in rats, enabling people to better understand the mechanisms related to genetics, diseases, drug effects, etc., which provides great help for the exploration of human diseases.

[0052] The rat fixation device can ensure that the rat maintains a relatively stable position during the experiment, reduce its movement and struggle, and thus reduce the rat's stress response.

[0053] Based on this, the present application provides a rat fixing device for experiments. In a specific operation process, the electric telescopic rod 21 is controlled to extend, thereby driving the fixing disc 22 to move upward.

[0054] Furthermore, the first motor 31 is started to drive the first gear 32 to rotate, and the first gear 32 is meshed with the first rack 33 to realize the support column 34 to move toward each other in the sliding groove provided on the fixed disc 22, so that the support discs 35 are staggered and approached to each other, and then the distance between the fixed frames 37 on the left and right sides is adjusted through the support frame 36 to achieve the clamping and fixation of the rat body.

[0055] Furthermore, the electric push rod 313 drives the half gear 311 to mesh with the second rack 310, thereby adjusting the distance between the front and rear fixing frames 37, thereby achieving the technical effect of clamping and fixing the rat body more stably.

[0056] After the rat's body is fixed, the airbag is inflated by the air pump 412 to expand the airbag, thereby achieving the purpose of clamping and fixing the base of the rat's legs. The characteristics of the airbag prevent the rat's legs from being injured during the clamping process.

[0057] According to the needs of the experiment, the rat's calf can be selectively fixed. Specifically, by pressing the pressing block 52, the locking blocks 54 are driven to move closer to each other, so that the spring 53 is stretched, and the locking block 54 is inserted into the locking hole 55, the squeezing of the pressing block 52 is released, and under the action of the elastic force of the spring 53, the locking block 54 and the locking hole 55 are locked and fixed, so that the calf fixing part 42 is fixed to the corresponding position.

[0058] Furthermore, the second motor 422 drives the second gear 423 to mesh with the toothed disc 424, thereby achieving the movement and approach of the movable push rod 427, thereby achieving the technical effect of fixing the rat's calf. Further, the water balloon 428 at the head end of the movable push rod 427 is provided to avoid damage to the rat's calf during fixed clamping.

[0059] After the experiment is over, the entire device can be stored in the base 1 by controlling the electric telescopic rod 21 to be retracted, so as to facilitate arrangement and placement.

[0060] It should be pointed out that for those skilled in the art, several modifications and improvements can be made without departing from the structure of the present invention, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The protection scope required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A rat fixing device for an experiment, comprising a base (1), Features: A lifting mechanism (2) is arranged inside the base (1), a body fixing mechanism (3) is arranged on the lifting mechanism (2), and a leg fixing mechanism (4) is arranged on the body fixing mechanism (3).

2. An experimental rat fixing device according to claim 1, Features: The leg fixing mechanism (4) comprises a thigh fixing portion (41) and a calf fixing portion (42); The calf fixing portion (42) is detachably connected to the body fixing mechanism (3) and corresponds to the thigh fixing portion (41).

3. An experimental rat fixing device according to claim 2, Features: The body fixing mechanism (3) comprises a first motor (31), a first gear (32), a first rack (33), a support column (34), a support plate (35), a support frame (36) and four sets of fixing frames (37); The first motor (31) is arranged on the lifting mechanism (2), and the output end of the first motor (31) is connected to a first gear (32); First racks (33) are symmetrically meshed on both sides of the first gear (32), and each end of the first rack (33) is fixedly connected to a support column (34); One end of the support column (34) is slidably connected to the lifting mechanism (2), and the other end is fixedly connected to the support plate (35); The support plate (35) is a two-half structure and is slidably connected in an offset manner up and down, and a support frame (36) of the two-half structure is correspondingly connected to the support plate (35); The four groups of fixing frames (37) are arranged on the supporting frame (36) in pairs.

4. The rat fixing device for experiments according to claim 3, Features: The body fixing mechanism (3) further comprises a connecting block (38), a support rod (39), a second rack (310), a half gear (311), a connecting rod (312), an electric push rod (313) and a fixing rod (314); Both ends of the support frame (36) are fixedly connected to connection blocks (38), and a movable groove is formed on the connection block (38); A support rod (39) is fixedly connected to each of the fixing frames (37), and an end of the support rod (39) is slidably connected to a connecting block (38) via a movable groove; A second rack (310) is provided at the bottom of each of the fixing frames (37), and a half gear (311) is meshed on each of the second racks (310); Each of the half gears (311) is rotatably connected to a connecting rod (312), and the ends of the two connecting rods (312) are rotatably connected to an electric push rod (313); The electric push rod (313) and the half gear (311) are both fixedly connected to the connecting block (38) via a fixing rod (314).

5. The rat fixing device for experiments according to claim 4, Features: The thigh fixing portion (41) comprises a fixing hole (411), an air pump (412) and an air pipe (413); Each of the fixing frames (37) is provided with a fixing hole (411) extending therethrough, and an air bag is arranged in the fixing hole (411); One end of the air tube (413) is connected to the air bag, and the other end is connected to the air pump (412).

6. The rat fixing device for experiments according to claim 5, Features: The calf fixing part (42) comprises a fixing sleeve (421), a second motor (422), a second gear (423), a toothed disc (424), a limiting groove (425), a limiting column (426), a movable push rod (427), a water balloon (428), a piston cylinder (429) and a hose (4210); One end of the fixing sleeve (421) is detachably connected to any one of the fixing frames (37) via a connecting piece (5), and the other end is provided with a second motor (422); The output end of the second motor (422) is connected to a second gear (423), and the second gear (423) is meshed with a toothed disc (424); The toothed disc (424) is provided with a plurality of limit slots (425), and each limit slot (425) is provided with a limit post (426) in a sliding manner. The end of the limiting column (426) is fixedly connected to a movable push rod (427), the movable push rod (427) is slidably connected to the fixed sleeve (421), and a plurality of water balloons (428) are arranged at the head end of the movable push rod (427); The fixed sleeve (421) is fixedly connected to a piston cylinder (429), and the side end of the movable push rod (427) is fixedly connected to a piston rod in the piston cylinder (429); The head end of the piston cylinder (429) is connected to a hose (4210), and the hose (4210) is in communication with the water balloon (428).

7. The rat fixing device for experiments according to claim 6, Features: The fixed sleeve (421) comprises a first sleeve and a second sleeve, and the first sleeve is slidably sleeved with the second sleeve.

8. The rat fixing device for experiments according to claim 7, Features: The connecting member (5) comprises a connecting tube (51), a pressing block (52), a spring (53) and a locking block (54); Connecting tubes (51) are symmetrically arranged on both sides of the first sleeve, and pressing blocks (52) are slidably arranged on both upper and lower sides of the connecting tube (51); The end of each pressing block (52) is fixedly connected to a locking block (54); One end of each of the springs (53) is connected to the inner wall of the connecting tube (51), and the other end is connected to the locking block (54); The locking block (54) matches with a locking hole (55) provided on the fixing frame (37).

9. The rat fixing device for experiments according to claim 3, Features: The lifting mechanism (2) comprises two electric telescopic rods (21) and a fixed disc (22); One end of each electric telescopic rod (21) is connected to the base (1), and the other end is connected to the bottom of the fixed disc (22); The fixed disc (22) is symmetrically provided with two sliding grooves, and the support column (34) is slidably connected to the fixed disc (22) via the sliding grooves.

10. A method for operating an experimental rat fixation device according to any one of claims 1 to 9, It is characterized in that The following steps are involved: S1: activating the lifting mechanism (2) so that the body fixing mechanism (3) and the leg fixing mechanism (4) extend from the base (1); S2: adjusting the body fixing mechanism (3) according to the body size of the rat to fix the body; S3: The rat's limbs are further separated and non-traumatically fixed using a leg fixing mechanism (4).

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