Circulating calcitonin gene related peptide detection kit

Abstract

The invention discloses a circulating calcitonin gene-related peptide detection kit, and relates to the technical field of diagnostic kits, the circulating calcitonin gene-related peptide detection kit comprises a kit main body, and also comprises a transfer thermal insulation unit, a positioning packaging unit and a cooling assembly which are arranged on the kit main body, the internal space of the kit main body is divided into an upper chamber and a lower chamber by the transverse partition plate; each adjusting heat preservation unit comprises a strip-shaped box, a lead screw, a guide block, an extension sleeve, a sealing cover plate, a vertical partition plate, a frame-shaped heat preservation plate, a center spring and a heat preservation cover plate. According to the kit, after the sealing cover plate is close to the sealing kit main body, the central spring can be matched with the heat preservation cover plate to abut against the opening end of the frame-shaped heat preservation plate to seal the left cavity and the right cavity, and the solid-phase calcitonin gene related peptide antibody and the detection auxiliary are sealed and stored; the equipment is flexible and stable in overall calling and sealing operation of the solid-phase calcitonin gene related peptide antibody and the detection auxiliary.

Description

Technical Field

[0001] The invention relates to the technical field of diagnostic kits, and in particular to a circulating calcitonin gene-related peptide detection kit. Background Art

[0002] Hypertension, especially essential hypertension in the elderly, is the primary risk factor for stroke, myocardial infarction and even cardiovascular death. Its effective management and control are crucial to reducing the disability and mortality rates of the elderly. The morning blood pressure peak phenomenon refers to the sharp increase in blood pressure in the morning, which is usually defined as the average systolic blood pressure value within 2 hours after waking up in the morning - the average systolic blood pressure value for 1 hour, including the lowest systolic blood pressure value at night.

[0003] The occurrence of morning peak hypertension after taking antihypertensive drugs clinically often represents the patient's sympathetic and parasympathetic nervous system interactions being dysregulated, the pressure receptor reflex sensitivity being decreased, and the drug's effect in controlling blood pressure being poor. In the management of hypertension, the time of taking medication depends on the patient's own laws of blood pressure fluctuations, the characteristics of antihypertensive drugs, and the duration of drug effects. Studies have found that taking long-acting calcium channel blockers at night can effectively prevent morning peak hypertension, but the specific time of taking medication must be determined based on blood pressure monitoring. Therefore, in clinical practice, the existing technology for predicting and diagnosing the occurrence of morning peak blood pressure and guiding the treatment of morning peak hypertension is mainly 24h dynamic blood pressure monitoring, and there are no available biomarkers to assist in diagnosis, monitor the efficacy of antihypertensive drugs, and guide the treatment of morning peak hypertension.

[0004] Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuroendocrine peptide that is secreted by nerve cells and vascular endothelial cells and is a potent vasodilator. It is widely distributed in the cardiovascular system. CGRP is the strongest vasodilator discovered so far and plays an important role in regulating the sensitivity of baroreceptor reflexes, thereby affecting blood pressure regulation. Studies have found that circulating CGRP is significantly increased in the morning peak group of elderly patients with primary hypertension, and the level of circulating CGRP is closely related to the morning peak phenomenon of blood pressure. Circulating CGRP can be used as a biomarker to predict the occurrence of morning peak phenomenon of blood pressure and to evaluate drug efficacy and individual adaptability after clinical medication for hypertension. However, there is currently a lack of a more convenient, rapid and accurate CGRP detection kit suitable for clinical use on the market. Existing CGRP detection kits are often complicated and time-consuming to operate and are not used for clinical diagnosis. For this reason, we propose a circulating CGRP detection kit. Summary of the invention

[0005] The main purpose of the present invention is to provide a circulating calcitonin gene-related peptide detection kit, which solves the problem that the existing calcitonin gene-related peptide detection kits are often complicated and time-consuming to operate and are not used for clinical diagnosis.

[0006] To solve the above technical problems, the present invention is implemented by the following technical solutions: a circulating calcitonin gene-related peptide detection kit, comprising a kit body, and also comprising: a mobilization and heat preservation unit, a positioning and packaging unit, and a cooling component arranged on the kit body, wherein a transverse partition is fixedly arranged in the kit body, and the transverse partition divides the internal space of the kit body into two upper and lower chambers; The mobilization and insulation unit comprises a strip box, a screw rod, a guide block, an extension sleeve, a closed cover plate, a vertical partition plate, a frame-shaped insulation plate, a center spring and an insulation cover plate, wherein the strip boxes are provided with two and are symmetrically fixedly arranged at the centers of the outer walls of the test kit body on both sides opposite to each other, the screw rod is movably arranged on the inner wall of one of the strip boxes and extends to the outside of the strip box, the guide blocks are provided with two and are respectively located in the two strip boxes, one of the guide blocks is threadedly connected to the screw rod, the two extension sleeves are respectively fixedly arranged on the end faces of the two guide blocks, the closed cover plate is fixedly arranged on the end faces of the two extension sleeves that are movably extended to the outside of the strip box, the frame-shaped insulation plate is fixedly arranged in the upper chamber, the vertical partition plate is fixedly arranged in the upper chamber and divides the upper chamber space into two left and right chambers, the center spring is embedded and installed on the top surface of one side of the closed cover plate, the insulation cover plate is fixedly arranged on the end face of the center spring, and the insulation cover plate extends into the upper chamber and abuts against the opening end of the frame-shaped insulation plate; The positioning packaging unit includes a storage frame, a carrying plate, a locking screw, a corner spring, a closed pressure plate and a microporous plate. A strip groove is provided on one side surface of the bottom end of the closed cover plate. The storage frame is fixedly arranged in the lower chamber. The carrying plate is movably arranged on the strip groove and extends into the storage frame. A positioning through hole is provided on the side of one end of the carrying plate located inside the strip groove. A threaded hole that is conductive to the strip groove is provided on the side of the closed cover plate. The locking screw is assembled on the threaded hole and movably extends into the positioning through hole. Several corner springs are fixedly arranged at the corners of the top surface inside the storage frame. The closed pressure plate is fixedly arranged at the bottom ends of several corner springs. The microporous plate is fixedly arranged on the top surface of the carrying plate and is located below the closed pressure plate. Several hole grooves for placing solid-phase calcitonin gene-related peptide antibodies are provided on the top surface of the microporous plate.

[0007] Preferably, the cooling component includes a temperature sensor, a thermostat and a cooler, and two of the temperature sensor, thermostat and cooler are provided and installed in left and right chambers respectively, wherein the left chamber mainly contains concentrated washing solution, biotinylated horseradish peroxidase conjugated detection antibody, stop solution, tetramethylbenzidine substrate, concentration gradient standard and other detection aids, and the concentrated washing solution, biotinylated horseradish peroxidase conjugated detection antibody, stop solution, tetramethylbenzidine substrate, concentration gradient standard and other detection aids are all packaged through medicine bottles, and the right chamber mainly contains the carrier plate and the microplate detached from the closed cover plate, and the solid phase calcitonin gene-related peptide antibody and the detection aids can be stored in a suitable low temperature environment respectively.

[0008] Preferably, the adjustable heat preservation unit further comprises a guide rod, which is fixedly arranged on the inner wall of another strip box and movably passes through another guide block.

[0009] Preferably, a turntable is fixedly provided on the end surface of the screw rod extending to the outside of the strip box.

[0010] Preferably, the locking screw and the lead screw are arranged perpendicular to each other.

[0011] Preferably, a support rod is fixedly arranged in the lower chamber, and a sealing film cylinder is mounted on the support rod.

[0012] Preferably, storage partitions are fixedly provided in both the left and right chambers.

[0013] Preferably, an observation window is embedded in the center of one side of the closed cover plate.

[0014] Preferably, anti-sliding blocks are fixedly provided at the corners of the bottom surface of the closed cover plate, and a total of a plurality of anti-sliding blocks are provided and distributed in a rectangular array.

[0015] Preferably, an instruction manual placement frame is fixedly provided on one side surface of the top of the reagent kit body.

[0016] Compared with the prior art, the circulating calcitonin gene-related peptide detection kit of the present invention has the following beneficial effects: 1. In the present invention, by setting a movable heat preservation unit, a vertical partition fixedly arranged in the upper chamber and dividing the upper chamber space into two left and right chambers can cooperate with the solid-phase calcitonin gene-related peptide antibody and the detection auxiliary to be stored separately at a suitable temperature under the cooperation of the cooling component, and the frame-shaped heat preservation plate fixedly arranged in the upper chamber can ensure that the temperature of the left and right chambers is maintained. The screw rod is held and rotated forward and backward outside the strip box. One of the guide blocks threadedly connected to the screw rod can be driven by force to translate the extension sleeve on the strip box to adjust the exposed area, and the closed cover plate can be driven by the extension sleeve to By adjusting the distance with the main body of the test kit, the other guide block can slide and translate on the guide rod to cooperate with the extension sleeve to mobilize and provide auxiliary support for it. The closed cover plate drives the thermal insulation cover plate away from the main body of the test kit to take out the solid-phase calcitonin gene-related peptide antibodies and detection aids. After the closed cover plate is close to the main body of the closed test kit, the central spring can cooperate with the thermal insulation cover plate to press against the opening end of the frame-shaped thermal insulation plate to close the left and right chambers, and the solid-phase calcitonin gene-related peptide antibodies and detection aids are sealed. The equipment's overall call and sealing operation for the solid-phase calcitonin gene-related peptide antibodies and detection aids is flexible and stable.

[0017] 2. In the present invention, by setting a positioning packaging unit, when not in use for a long time, the carrier plate and the microplate with the solid-phase calcitonin gene-related peptide antibody can be placed in the right chamber. When performing the detection work, the closed cover plate is moved away from the closed reagent kit body, and one end of the carrier plate with a positioning through hole on the side surface can be inserted into the strip groove on the surface of one side of the bottom end of the closed cover plate, and the locking screw is rotated to the threaded hole connected to the strip groove. The locking screw is rotated into the positioning through hole to help the carrier plate to be locked and assembled to the closed cover plate, and the microplate is locked. The loading plate can be moved in and out of the reagent kit body to complete the call by following the movement of the closing cover plate; the microplate with the solid-phase calcitonin gene-related peptide antibody can be placed in the storage frame fixed in the lower chamber after being temporarily sealed by the sealing film; the corner springs fixed at the corners of the top surface of the storage frame can cooperate with the closing pressure plate to fix the sealing film tightly on the top surface of the microplate to ensure the packaging and preservation effect of the solid-phase calcitonin gene-related peptide antibody; the equipment is flexible and convenient for temporarily calling and sealing the solid-phase calcitonin gene-related peptide antibody when used for detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 This is a schematic diagram of the overall structure of a circulating calcitonin gene-related peptide detection kit of the present invention; Figure 2 This is a schematic diagram of the top view of a circulating calcitonin gene-related peptide detection kit of the present invention; Figure 3 For the present invention Figure 2 Schematic diagram of the cross-sectional structure at AA in the middle; Figure 4 For the present invention Figure 2 Schematic diagram of the cross-sectional structure at the middle BB; Figure 5 For the present invention Figure 3 Schematic diagram of the cross-section structure at CC in the middle; Figure 6 For the present invention Figure 5 Schematic diagram of the cross-sectional structure at DD in the middle.

[0020] In the accompanying drawings, the components represented by the reference numerals are listed as follows: 1. Test kit body; 2. Move the heat preservation unit; 201. Strip box; 202. Screw rod; 203. Guide block; 204. Extension sleeve; 205. Closed cover plate; 206. Vertical partition plate; 207. Frame-shaped heat preservation plate; 208. Center spring; 209. Heat preservation cover plate; 2010. Guide rod; 3. Positioning packaging unit; 301. Storage frame; 302. Carrying plate; 303. Locking screw; 304. Corner spring; 305. Closing pressure plate; 306. Microplate; 4. Cooling component; 401. Temperature sensor; 402. Thermostat; 403. Cooling device; 5. Horizontal partition; 6. Turntable; 7. Support rod; 8. Sealing film tube; 9. Storage partition; 10. Observation window; 11. Anti-sliding block; 12. Instruction manual placement frame. DETAILED DESCRIPTION

[0021] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0022] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0023] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. Example

[0024] like Figure 1 , Figure 2 , Figure 3 , Figure 4 as well as Figure 5 As shown, a circulating calcitonin gene-related peptide detection kit includes a kit body 1, and also includes: a mobilization and heat preservation unit 2, a positioning and packaging unit 3, and a cooling component 4 arranged on the kit body 1, and a transverse partition 5 is fixedly arranged in the kit body 1, and the transverse partition 5 divides the internal space of the kit body 1 into two upper and lower chambers; The mobilization insulation unit 2 includes a strip box 201, a screw rod 202, a guide block 203, an extension sleeve 204, a closed cover plate 205, a vertical partition 206, a frame-shaped insulation plate 207, a center spring 208 and an insulation cover plate 209. The strip boxes 201 are provided with two and are symmetrically fixed at the center of the outer walls of the reagent box body 1 on both sides. The screw rod 202 is movably provided on the inner wall of one of the strip boxes 201 and extends to the outside of the strip box 201. There are two guide blocks 203 and they are respectively located in the two strip boxes 201. One of the guide blocks 203 is threadedly connected to the screw rod 202. , two extension sleeves 204 are fixedly arranged on the end surfaces of the two guide blocks 203 respectively, the closed cover plate 205 is fixedly arranged on the end surfaces of the two extension sleeves 204 that are movably extended to the outside of the strip box 201, the frame-shaped insulation board 207 is fixedly arranged in the upper chamber, the vertical partition plate 206 is fixedly arranged in the upper chamber and divides the upper chamber space into two left and right chambers, the center spring 208 is embedded and installed on the top surface of one side of the closed cover plate 205, the insulation cover plate 209 is fixedly arranged on the end surface of the center spring 208, and the insulation cover plate 209 extends into the upper chamber and abuts against the open end of the frame-shaped insulation board 207; The positioning packaging unit 3 includes a storage frame 301, a carrying plate 302, a locking screw 303, a corner spring 304, a closed pressure plate 305 and a micro-porous plate 306. A strip groove is provided on one side of the bottom end of the closed cover plate 205. The storage frame 301 is fixedly arranged in the lower chamber. The carrying plate 302 is movably arranged on the strip groove and extends into the storage frame 301. A positioning through hole is provided on the side of one end of the carrying plate 302 located inside the strip groove. The closed cover plate 205 has a side opening. A threaded hole is provided which is in communication with the strip groove, a locking screw 303 is assembled on the threaded hole and movably extends into the positioning through hole, a plurality of corner springs 304 are fixedly arranged at the corners of the top surface inside the storage frame 301, a closed pressure plate 305 is fixedly arranged at the bottom ends of the plurality of corner springs 304, a microporous plate 306 is fixedly arranged on the top surface of the carrier plate 302 and is located below the closed pressure plate 305, and a plurality of slots for placing solid-phase calcitonin gene-related peptide antibodies are provided on the top surface of the microporous plate 306.

[0025] The cooling component 4 includes a temperature sensor 401 , a thermostat 402 and a cooler 403 . Two of each of the temperature sensor 401 , the thermostat 402 and the cooler 403 are provided and are installed in the left and right chambers respectively.

[0026] The heat preservation unit 2 further comprises a guide rod 2010 , which is fixedly arranged on the inner wall of another strip box 201 and movably passes through another guide block 203 .

[0027] The end surface of the screw rod 202 extending to the outside of the strip box 201 is fixedly provided with a turntable 6.

[0028] Among them, storage partitions 9 are fixedly arranged in both the left and right chambers.

[0029] An observation window 10 is embedded in the center of one side of the closed cover plate 205 .

[0030] Among them, anti-sliding blocks 11 are fixedly arranged at the corners of the bottom surface of the closed cover plate 205, and a total of several anti-sliding blocks 11 are arranged and distributed in a rectangular array.

[0031] Among them, an instruction manual placement frame 12 is fixedly arranged on one side surface of the top of the reagent kit body 1 .

[0032] By mobilizing the heat preservation unit 2, the equipment can flexibly and stably call and seal the solid-phase calcitonin gene-related peptide antibody and detection auxiliary materials as a whole. Example

[0033] like Figure 1 , Figure 3 , Figure 4 , Figure 5 as well as Figure 6 As shown, a circulating calcitonin gene-related peptide detection kit includes a kit body 1, and also includes: a mobilization and heat preservation unit 2, a positioning and packaging unit 3, and a cooling component 4 arranged on the kit body 1, and a transverse partition 5 is fixedly arranged in the kit body 1, and the transverse partition 5 divides the internal space of the kit body 1 into two upper and lower chambers; The mobilization insulation unit 2 includes a strip box 201, a screw rod 202, a guide block 203, an extension sleeve 204, a closed cover plate 205, a vertical partition 206, a frame-shaped insulation plate 207, a center spring 208 and an insulation cover plate 209. The strip boxes 201 are provided with two and are symmetrically fixed at the center of the outer walls of the reagent box body 1 on both sides. The screw rod 202 is movably provided on the inner wall of one of the strip boxes 201 and extends to the outside of the strip box 201. There are two guide blocks 203 and they are respectively located in the two strip boxes 201. One of the guide blocks 203 is threadedly connected to the screw rod 202. , two extension sleeves 204 are fixedly arranged on the end surfaces of the two guide blocks 203 respectively, the closed cover plate 205 is fixedly arranged on the end surfaces of the two extension sleeves 204 that are movably extended to the outside of the strip box 201, the frame-shaped insulation board 207 is fixedly arranged in the upper chamber, the vertical partition plate 206 is fixedly arranged in the upper chamber and divides the upper chamber space into two left and right chambers, the center spring 208 is embedded and installed on the top surface of one side of the closed cover plate 205, the insulation cover plate 209 is fixedly arranged on the end surface of the center spring 208, and the insulation cover plate 209 extends into the upper chamber and abuts against the open end of the frame-shaped insulation board 207; The positioning packaging unit 3 includes a storage frame 301, a carrying plate 302, a locking screw 303, a corner spring 304, a closed pressure plate 305 and a micro-porous plate 306. A strip groove is provided on one side of the bottom end of the closed cover plate 205. The storage frame 301 is fixedly arranged in the lower chamber. The carrying plate 302 is movably arranged on the strip groove and extends into the storage frame 301. A positioning through hole is provided on the side of one end of the carrying plate 302 located inside the strip groove. The closed cover plate 205 has a side opening. A threaded hole is provided which is in communication with the strip groove, a locking screw 303 is assembled on the threaded hole and movably extends into the positioning through hole, a plurality of corner springs 304 are fixedly arranged at the corners of the top surface inside the storage frame 301, a closed pressure plate 305 is fixedly arranged at the bottom ends of the plurality of corner springs 304, a microporous plate 306 is fixedly arranged on the top surface of the carrier plate 302 and is located below the closed pressure plate 305, and a plurality of slots for placing solid-phase calcitonin gene-related peptide antibodies are provided on the top surface of the microporous plate 306.

[0034] The cooling component 4 includes a temperature sensor 401 , a thermostat 402 and a cooler 403 . Two of each of the temperature sensor 401 , the thermostat 402 and the cooler 403 are provided and are installed in the left and right chambers respectively.

[0035] The locking screw 303 and the screw rod 202 are arranged perpendicular to each other.

[0036] A support rod 7 is fixedly arranged in the lower chamber, and a sealing film tube 8 is installed on the support rod 7 .

[0037] Among them, storage partitions 9 are fixedly arranged in both the left and right chambers.

[0038] An observation window 10 is embedded in the center of one side of the closed cover plate 205 .

[0039] By positioning the encapsulation unit 3, the device can flexibly and conveniently call and seal the solid-phase calcitonin gene-related peptide antibody for a short period of time when used for detection.

[0040] The following is the working principle of the present invention: A vertical partition 206 fixedly arranged in the upper chamber and dividing the upper chamber space into two left and right chambers cooperates with the solid-phase calcitonin gene-related peptide antibody and the detection auxiliary to store separately at a suitable temperature under the cooperation of the cooling component 4. A frame-shaped insulation plate 207 fixedly arranged in the upper chamber ensures that the temperature of the left and right chambers is maintained. The screw rod 202 is held and rotated forward and backward outside the strip box 201. One of the guide blocks 203 threadedly connected to the screw rod 202 is driven by force to translate the extension sleeve 204 on the strip box 201 to adjust the exposed area. The closed cover plate 205 is driven by the extension sleeve 204 to adjust the distance with the reagent box body 1, and the other guide block 203 slides and translates on the guide rod 2010 to cooperate with the extension sleeve 204 to adjust, and the closed cover plate 205 drives the heat preservation cover plate 209 to move away from the reagent box body 1 so that the solid phase calcitonin gene-related peptide antibody and the detection auxiliary can be taken. After the closed cover plate 205 is close to the closed reagent box body 1, the central spring 208 cooperates with the heat preservation cover plate 209 to press against the open end of the frame-shaped heat preservation plate 207 to close the left and right chambers, and the solid phase calcitonin gene-related peptide antibody and the detection auxiliary can be taken. The calcitonin gene-related peptide antibody and the detection aids are sealed. When not used for a long time, the carrier plate 302 and the microplate 306 with the solid-phase calcitonin gene-related peptide antibody are placed in the right chamber. When the detection work is carried out, the closed cover plate 205 is moved away from the closed reagent kit body 1, and the end of the carrier plate 302 with a positioning through hole on the upper side is inserted into the strip groove on the surface of one side of the bottom end of the closed cover plate 205, and the locking screw 303 is rotated to the threaded hole connected to the strip groove. The locking screw 303 is rotated into the positioning through hole to help the carrier plate 3 02 is locked and assembled on the closed cover 205, and the microplate 306 is called in and out of the reagent kit body 1 by following the movement of the closed cover 205 through the carrier plate 302. The microplate 306 with the solid-phase calcitonin gene-related peptide antibody is placed in the storage frame 301 fixed in the lower chamber after being briefly sealed by the sealing film. The corner springs 304 at the corners of the top surface of the storage frame 301 cooperate with the closed pressure plate 305 to fix the sealing film tightly on the top surface of the microplate 306 to ensure the packaging and preservation effect of the solid-phase calcitonin gene-related peptide antibody.

[0041] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A circulating calcitonin gene-related peptide detection kit, comprising a kit body (1), characterized in that: Also includes: A mobilizing and heat-insulating unit (2), a positioning and packaging unit (3), and a cooling component (4) are arranged on the reagent box body (1); a transverse partition (5) is fixedly arranged inside the reagent box body (1); the transverse partition (5) divides the internal space of the reagent box body (1) into two upper and lower chambers; The mobilizing heat-insulating unit (2) comprises a strip box (201), a screw rod (202), a guide block (203), an extension sleeve (204), a closed cover plate (205), a vertical partition plate (206), a frame-shaped heat-insulating plate (207), a central spring (208) and a heat-insulating cover plate (209). The strip boxes (201) are provided with two and are symmetrically fixedly arranged at the center of the outer walls of the reagent box body (1) on both sides opposite to each other. The screw rod (202) is movably arranged on the inner wall of one of the strip boxes (201) and extends to the outside of the strip box (201). The guide blocks (203) are provided with two and are respectively located in the two strip boxes (201). One of the guide blocks (203) is connected to the screw rod (202). The two extension sleeves (204) are respectively fixedly arranged on the end surfaces of the two guide blocks (203); the closed cover plate (205) is fixedly arranged on the end surfaces of the two extension sleeves (204) that are movably extended to the outside of the strip box (201); the frame-shaped insulation plate (207) is fixedly arranged in the upper chamber; the vertical partition plate (206) is fixedly arranged in the upper chamber and divides the upper chamber space into two left and right chambers; the center spring (208) is embedded and installed on the top surface of one side of the closed cover plate (205); the insulation cover plate (209) is fixedly arranged on the end surface of the center spring (208); and the insulation cover plate (209) extends into the upper chamber and abuts against the open end of the frame-shaped insulation plate (207); The positioning packaging unit (3) comprises a storage frame (301), a carrying plate (302), a locking screw (303), a corner spring (304), a closed pressure plate (305) and a micro-porous plate (306); a strip groove is provided on one side surface of the bottom end of the closed cover plate (205); the storage frame (301) is fixedly arranged in the lower chamber; the carrying plate (302) is movably arranged on the strip groove and extends into the storage frame (301); a positioning through hole is provided on the side surface of one end of the carrying plate (302) located inside the strip groove; the closed cover plate (205) is provided with a plurality of positioning holes; 05) A threaded hole communicating with the strip groove is opened on the side, the locking screw (303) is assembled on the threaded hole and movably extends into the positioning through hole, a plurality of the corner springs (304) are fixedly arranged at the corners of the top surface inside the storage frame (301), the closed pressure plate (305) is fixedly arranged at the bottom ends of the plurality of corner springs (304), the microporous plate (306) is fixedly arranged on the top surface of the carrier plate (302) and is located below the closed pressure plate (305), and a plurality of slots for placing solid-phase calcitonin gene-related peptide antibodies are opened on the top surface of the microporous plate (306).

2. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: The cooling component (4) comprises a temperature sensor (401), a thermostat (402) and a cooler (403); two of each of the temperature sensor (401), the thermostat (402) and the cooler (403) are provided and are installed in the left and right chambers respectively.

3. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: The movable heat-insulating unit (2) further comprises a guide rod (2010), wherein the guide rod (2010) is fixedly arranged on the inner wall of another strip-shaped box (201) and movably passes through another guide block (203).

4. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: A rotating disk (6) is fixedly disposed on the end surface of the lead screw (202) extending to the outside of the strip box (201).

5. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: The locking screw (303) and the lead screw (202) are arranged perpendicular to each other.

6. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: A support rod (7) is fixedly arranged in the lower chamber, and a sealing film cylinder (8) is mounted on the support rod (7).

7. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: Storage partitions (9) are fixedly arranged in both the left and right chambers.

8. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: An observation window (10) is embedded and installed at the center of one side of the closed cover plate (205).

9. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: Anti-sliding blocks (11) are fixedly arranged at the corners of the bottom surface of the closed cover plate (205), and a total of a plurality of anti-sliding blocks (11) are arranged in a rectangular array.

10. A circulating calcitonin gene-related peptide detection kit according to claim 1, characterized in that: An instruction manual placement frame (12) is fixedly arranged on one side surface of the top of the reagent kit body (1).

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