Auto-cleanable enzymatic hydrolysis furnace for polypeptide preparation

Abstract

The present invention relates to the technical field of enzymatic hydrolysis, and specifically relates to an enzymatic hydrolysis furnace for polypeptide preparation that can be automatically cleaned, including an enzymatic hydrolysis furnace body, a stirring structure, a driving mechanism, and an automatic cleaning mechanism; the enzymatic hydrolysis furnace body includes a tank body and a cover body, and a plurality of cleaning windows are annularly and arrayedly opened on the tank body; the stirring structure is arranged inside the tank body; the driving mechanism is used to drive the stirring structure to move; the automatic cleaning mechanism includes a plurality of high-pressure water pipes, and the plurality of high-pressure water pipes correspond to the plurality of cleaning windows respectively. The high-pressure water pipe includes a cleaning part and a water supply part. The cleaning part is closely attached to the cleaning window, and a plurality of spray heads are arranged on the cleaning part. The plurality of spray heads all face the inside of the tank body, and the plurality of spray heads are arranged along the generatrix of the high-pressure water pipe. The water supply part is located at the lower end of the cleaning part, and the water supply part is externally connected to a pressurized water supply device; the present invention is provided with a stirring structure, a driving mechanism, and an automatic cleaning mechanism, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank body, the stirring shaft, and the stirring blades.

Description

Technical Field

[0001] The present invention relates to the technical field of enzymatic hydrolysis, and specifically relates to an enzymatic hydrolysis furnace for polypeptide preparation that can be automatically cleaned. Background Art

[0002] The enzymatic hydrolysis furnace for polypeptide preparation is a device specifically used for the enzymatic hydrolysis reaction in the process of polypeptide preparation. Enzymatic hydrolysis is a decomposition reaction catalyzed by enzymes, specifically manifested as a process of decomposing macromolecular compounds into small molecular compounds.

[0003] For the enzymatic hydrolysis furnace for polypeptide preparation disclosed in Chinese Patent CN212533017U, a water injection port on one side of the fixed column is connected to a water pipe. Because the water inlet channel provided inside the rotating column is connected to the water injection port and the small nozzle, water flow will flow into the small nozzle, and a jet of water will be formed to clean the inner wall of the enzymatic hydrolysis furnace body during the rotation of the rotating column.

[0004] In the above solution, the following problems still exist:

[0005] 1. The water flow moves from the rotating column towards the inner wall of the enzymatic hydrolysis furnace body. The distance between the water outlet on the rotating column and the enzymatic hydrolysis furnace is relatively far, which will reduce the impact force of the water flow. At the same time, the water outlet on the rotating column moves synchronously with the paddle component, and the acting force of the paddle component hitting the water flow is small, resulting in a poor splashing effect of the water flow, and thus a poor cleaning effect of the water flow on the inner wall of the enzymatic hydrolysis furnace body;

[0006] 2. One side surface of the paddle component is in contact with the water flow, while it is difficult for the other side surface of the paddle component to be in contact with the water flow, resulting in difficulty in cleaning the other side of the paddle. Summary of the Invention

[0007] In view of the above problems, an enzymatic hydrolysis furnace for polypeptide preparation that can be automatically cleaned is provided. The present invention is provided with a stirring structure, a driving mechanism and an automatic cleaning mechanism, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank body, the stirring shaft and the stirring blades.

[0008] To solve the problems of the existing technology, the present invention provides an enzymolysis furnace for polypeptide preparation that can be automatically cleaned, comprising an enzymolysis furnace body, a stirring structure, a driving mechanism, and an automatic cleaning mechanism; the enzymolysis furnace body includes a tank body and a cover body, a plurality of cleaning windows are annularly and arrayedly opened on the tank body, the plurality of cleaning windows penetrate through the side wall of the tank body, and the cover body is covered on the upper end of the tank body; the stirring structure is arranged inside the tank body; the driving mechanism is arranged on the upper end of the cover body, and the driving mechanism is used to drive the stirring structure to move; the automatic cleaning mechanism is arranged outside the tank body, the automatic cleaning mechanism includes a plurality of high-pressure water pipes, the plurality of high-pressure water pipes respectively correspond to the plurality of cleaning windows, the high-pressure water pipe includes a cleaning part and a water supply part, the cleaning part is closely attached to the cleaning window, a plurality of spray heads are arranged on the cleaning part, the plurality of spray heads all face the inside of the tank body, and the plurality of spray heads are arranged along the generatrix of the high-pressure water pipe, the water supply part is located at the lower end of the cleaning part, and the water supply part is externally connected to a pressurized water supply device.

[0009] Preferably, the driving mechanism includes a first driving structure and a second driving structure; the first driving structure is arranged on one side above the cover body, and the first driving structure is used to drive the stirring structure to stir various raw materials in the tank body; the second driving structure is arranged on the other side above the cover body, and the second driving structure is used to drive the stirring structure to clean the inner wall of the tank body.

[0010] Preferably, the driving mechanism further includes a switching structure, the switching structure is arranged between the first driving structure and the second driving structure, the switching structure includes a U-shaped frame, a first connection structure, a second connection structure, and a synchronous driving structure; the U-shaped frame covers the upper part of the first driving structure and the second driving structure, and the U-shaped frame is connected to the cover body, and a first installation groove and a second installation groove are symmetrically opened on the U-shaped frame; the first connection structure is arranged in the first installation groove, and the first connection structure connects the first driving structure with the U-shaped frame; the second connection structure is arranged in the second installation groove, and the second connection structure connects the second driving structure with the U-shaped frame; the synchronous driving structure is arranged on one side of the U-shaped frame, and the synchronous driving structure is used to drive the first driving structure and the second driving structure to move synchronously.

[0011] Preferably, the automatic cleaning mechanism further includes a first installation bin, a second installation bin, a first opening and closing mechanism, and a rotating mechanism; the first installation bin is arranged at the bottom of the tank body; the second installation bin is arranged at the bottom of the first installation bin; the first opening and closing mechanism is arranged in the first installation bin, and the first opening and closing mechanism is used to drive the plurality of high-pressure water pipes to move away from or closely attach to the cleaning windows; the rotating mechanism is arranged in the second installation bin, and the rotating mechanism is used to drive the plurality of high-pressure water pipes to rotate so that the spray heads of the high-pressure water pipes face away from the inner side of the tank body.

[0012] Preferably, a strip-shaped sealing block is further arranged on the high-pressure water pipe, and the strip-shaped sealing block is arranged along the generatrix of the high-pressure water pipe.

[0013] Preferably, the first opening and closing mechanism includes a fixed column, a driving plate, a plurality of driving arm assemblies, and a second linear driver. The fixed column is arranged at the bottom of the tank body, and the axis of the fixed column is collinear with the central axis of the tank body; the driving plate is connected to the fixed column through a bearing, the axis of the driving plate is collinear with the axis of the fixed column, and the driving plate has a plurality of corners; the plurality of driving arm assemblies are respectively arranged at the plurality of corners of the driving plate, and the plurality of driving arm assemblies connect the driving plate to the lower ends of the plurality of high-pressure water pipes; the second linear driver is arranged on one side of the driving plate, and the second linear driver is used to push the driving plate to rotate around the axis of the fixed column.

[0014] Preferably, the automatic cleaning mechanism further includes a second opening and closing mechanism. The second opening and closing mechanism is arranged inside the cover body. The structure of the second opening and closing mechanism is the same as that of the first opening and closing mechanism, and the second opening and closing mechanism is connected to the upper ends of the plurality of high-pressure water pipes.

[0015] Preferably, the rotating mechanism includes a plurality of driven wheels, a synchronous transmission belt, a tensioning structure, and a third driving structure; the plurality of driven wheels correspond to the plurality of high-pressure water pipes respectively, and the driven gears are installed at the lower ends of the high-pressure water pipes; the synchronous transmission belt is connected to the plurality of driven wheels; the tensioning structure is arranged in the middle of the plurality of driven wheels, and the tensioning structure keeps the synchronous transmission belt in a tensioned state; the third driving structure is arranged in the second installation bin, and the third driving structure is used to drive one of the driven wheels to rotate.

[0016] Preferably, the rotating mechanism further includes a synchronous moving structure, and the synchronous moving structure connects the third driving structure to the driving arm assembly.

[0017] Preferably, the automatic cleaning mechanism further includes a fixing mechanism. The fixing mechanism is arranged at the bottom of the tank body. The fixing mechanism includes two clamping plates and a fourth driving structure; the two clamping plates are respectively arranged at both ends of the driving plate; the fourth driving structure is arranged between the two clamping plates.

[0018] The beneficial effects of the present invention compared with the prior art are as follows:

[0019] 1. The present invention is provided with a stirring structure, a driving mechanism, and an automatic cleaning mechanism. The external pressurized water supply device supplies cleaning water into the high-pressure water pipes. The high-pressure water sprays out from the nozzles. Under the action of high pressure, the water flow can spray to the middle of the tank body. At the same time, the driving mechanism drives the stirring structure to rotate, and the stirring blades rotate at a high speed relative to the inner wall of the tank body, while the water flow is stationary relative to the inner wall of the tank body. The high-speed rotating stirring blades collide with the water flow, and the water flow will be slapped by the stirring blades and hit the inner wall of the tank body. After the water flow hits the inner wall of the tank body and rebounds, it contacts the stirring blades again. This repeats, so that the water flow has a large impact force each time it contacts the inner wall of the tank body and the stirring blades, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank body, the stirring shaft, and the stirring blades.

[0020] 2. The present invention is provided with a second driving structure. The first linear driver first drives the mounting block to move from one end of the guide rod to the other end. The mounting block drives the transmission rack to move from one end of the guide rod to the other end. The transmission rack drives the stirring shaft to rotate forward through the driven gear. The stirring shaft drives the stirring blades to rotate forward. One side surface of the stirring blades contacts the cleaning water. Then, the first linear driver drives the mounting block to return to its original position. The mounting block drives the stirring shaft to rotate reversely through the transmission rack and the driven gear. The stirring shaft drives the stirring blades to rotate reversely. The other side surface of the stirring blades contacts the cleaning water, thereby realizing the cleaning of both side surfaces of the stirring blades.

[0021] 3. The present invention is provided with a switching structure. When the stirring blades stir the raw materials, the first screw rotates forward. The two connecting blocks drive the first moving block and the second moving block to move in one direction respectively. The first moving block drives the first rotary driver to move towards the driven gear. The driving gear meshes with the driven gear, so that the stirring blades continuously rotate in one direction. When the self-cleaning mechanism works, the first screw rotates reversely. The first moving block and the second moving block move in opposite directions. The driving gear disengages from the driven gear, and the transmission rack meshes with the driven gear, so that the stirring blades swing reciprocally, thereby avoiding the problem of mutual interference between the first driving structure and the second driving structure, and enabling the stirring structure to have two working modes. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 is a perspective view of an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0023] Figure 2 is a front view of an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0024] Figure 3 is Figure 2 a cross-sectional view taken along line A-A in

[0025] Figure 4 is a perspective view of the cover body, stirring shaft and driving mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0026] Figure 5 is a perspective view of the stirring shaft, driven gear, first driving structure and second driving structure in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0027] Figure 6 is a perspective view of the switching structure in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0028] Figure 7 is a perspective view of the high-pressure water pipe, first installation chamber, second installation chamber, first opening and closing mechanism and rotating mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0029] Figure 8It is a three-dimensional view of the high-pressure water pipe, the first opening and closing mechanism, the rotating mechanism, and the fixing mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0030] Figure 9 It is a three-dimensional view of the high-pressure water pipe and the first opening and closing mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0031] Figure 10 It is a three-dimensional view of the cover body, the high-pressure water pipe, the first opening and closing mechanism, and the second opening and closing mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0032] Figure 11 It is a three-dimensional view of the high-pressure water pipe and the rotating mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0033] Figure 12 It is a three-dimensional view of the high-pressure water pipe, the driving plate, the driving arm assembly, the driven wheel, the third driving structure, and the synchronous moving structure in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0034] Figure 13 It is a three-dimensional view of the fixing column, the driving plate, and the fixing mechanism in an enzymolysis furnace for polypeptide preparation that can be automatically cleaned.

[0035] The reference numerals in the figure are: 1. Enzymolysis furnace body; 11. Tank body; 111. Cleaning window; 12. Cover body; 2. Stirring structure; 21. Stirring shaft; 211. Driven gear; 22. Stirring blade; 3. Driving mechanism; 31. First driving structure; 311. Driving gear; 312. First rotary driver; 32. Second driving structure; 321. Transmission rack; 322. Mounting block; 323. Guide structure; 3231. Guide rod; 3232. First spring; 324. First linear driver; 33. Switching structure; 331. U-shaped frame; 332. First connection structure; 3321. First U-shaped plate; 3322. First guiding cross bar; 3323. First moving block; 333. Second connection structure; 3331. Second U-shaped plate; 3332. Second guiding cross bar; 3333. Second moving block; 3334. Mounting plate; 334. Synchronous driving structure; 3341. Connection block; 3342. First screw; 4. Automatic cleaning mechanism; 41. High-pressure water pipe; 411. Sprayer; 412. Strip-shaped sealing block; 42. First installation bin; 43. Second installation bin; 44. First opening and closing mechanism; 441. Fixed column; 442. Driving plate; 443. Driving arm assembly; 4431. First driving arm; 4432. Second driving arm; 4433. Limiting sleeve; 444. Second linear driver; 45. Second opening and closing mechanism; 46. Rotating mechanism; 461. Driven wheel; 462. Synchronous transmission belt; 463. Tensioning structure; 464. Third driving structure; 4641. Driving wheel; 4642. Second rotary driver; 465. Synchronous moving structure; 4651. First rectangular frame; 4652. Third guiding cross bar; 4653. Third moving block; 4654. Connecting plate; 4655. Connecting column; 47. Fixing mechanism; 471. Clamping plate; 472. Fourth driving structure; 4721. Second rectangular frame; 4722. Second screw; 4723. Fourth guiding cross bar; 4724. Fourth moving block; 4725. Third rotary driver. Detailed implementation mode

[0036] In order to further understand the features, technical means, specific purposes and functions achieved by the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific implementation modes.

[0037] Refer to Figures 1 to 13As shown: An enzymolysis furnace for polypeptide preparation that can be automatically cleaned, comprising an enzymolysis furnace body 1, a stirring structure 2, a driving mechanism 3, and an automatic cleaning mechanism 4; the enzymolysis furnace body 1 includes a tank body 11 and a cover body 12. A number of cleaning windows 111 are annularly and arrayedly opened on the tank body 11, and the number of cleaning windows 111 penetrate through the side wall of the tank body 11. The upper end of the tank body 11 is provided with a feeding port, and the lower end of the tank body 11 is provided with a discharging port. The cover body 12 is covered on the upper end of the tank body 11; the stirring structure 2 is arranged inside the tank body 11. The stirring structure 2 includes a stirring shaft 21 and a number of stirring blades 22. The axis of the stirring shaft 21 is collinear with the central axis of the tank body 11. One end of the stirring shaft 21 extends upward out of the cover body 12, and a driven gear 211 is coaxially arranged at one end of the stirring shaft 21. The number of stirring blades 22 are installed on the stirring shaft 21; the driving mechanism 3 is arranged on the upper end of the cover body 12. The driving mechanism 3 is used to drive the stirring structure 2 to move. The driving mechanism 3 drives the stirring shaft 21 to rotate by driving the driven gear 211; the automatic cleaning mechanism 4 is arranged outside the tank body 11. The automatic cleaning mechanism 4 includes a number of high-pressure water pipes 41. The number of high-pressure water pipes 41 respectively correspond to the number of cleaning windows 111. The high-pressure water pipe 41 includes a cleaning part and a water supply part. The cleaning part is closely attached to the cleaning window 111. A number of spray heads 411 are arranged on the cleaning part. The number of spray heads 411 all face the inside of the tank body 11, and the number of spray heads 411 are arranged along the generatrix of the high-pressure water pipe 41. The water supply part is located at the lower end of the cleaning part, and the water supply part is externally connected to a pressurized water supply device.

[0038] The raw materials for polypeptide preparation are put into the inside of the tank body 11 from the feeding port. The driving mechanism 3 drives the stirring structure 2 to move. The stirring structure 2 stirs the raw materials evenly. After the polypeptide preparation is completed, it is discharged from the discharging port. At this time, the inner wall of the tank body 11 and the stirring blades 22 are both attached with enzymolyzed substances. The external pressurized water supply device supplies cleaning water into the high-pressure water pipe 41. The high-pressure water sprays out from the spray heads 411. Under the action of high pressure, the water flow can spray to the middle of the tank body 11. At the same time, the driving mechanism 3 drives the stirring structure 2 to rotate. The stirring blades 22 rotate at a high speed relative to the inner wall of the tank body 11, while the water flow is stationary relative to the inner wall of the tank body 11. The high-speed rotating stirring blades 22 collide with the water flow. The water flow will be slapped by the stirring blades 22 and hit the inner wall of the tank body 11. The water flow rebounds after hitting the inner wall of the tank body 11 and contacts the stirring blades 22 again. This repeats, so that the water flow has a large impact force each time it contacts the inner wall of the tank body 11 and the stirring blades 22, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank body 11, the stirring shaft 21, and the stirring blades 22.

[0039] Refer to Figure 4 and Figure 5As shown: the driving mechanism 3 includes a first driving structure 31 and a second driving structure 32; the first driving structure 31 is arranged on one side above the cover 12, and the first driving structure 31 is used to drive the stirring structure 2 to stir various raw materials in the tank body 11, and the first driving structure 31 includes a driving gear 311 and a first rotating driver 312, the driving gear 311 is meshed with the driven gear 211, and the first rotating driver 312 is used to drive the driving gear 311 to rotate; the second driving structure 32 is arranged on the other side above the cover 12, and the second driving structure 32 is used to drive the stirring structure 2 to clean the inner wall of the tank body 11, and the second driving structure 32 includes a transmission rack 321, a mounting block 322, a guide structure 323 and a first linear driver 32 4. The transmission rack 321 is meshed with the driven gear 211. The mounting block 322 is arranged at one side of the transmission rack 321, and the transmission rack 321 is installed on the mounting block 322. The guide structure 323 is arranged at one end of the mounting block 322. The guide structure 323 includes a guide rod 3231 and a first spring 3232. One end of the guide rod 3231 is inserted into the mounting block 322. The first spring 3232 is sleeved on the guide rod 3231. The two ends of the first spring 3232 are respectively abutted against the end of the mounting block 322 and the end of the guide rod 3231. The first linear driver 324 is arranged at the other end of the mounting block 322. The first linear driver 324 is used to drive the mounting block 322 to reciprocate along the guide rod 3231.

[0040] High-pressure water is sprayed from the nozzle 411 to the interior of the tank body 11, and the first rotary driver 312 drives the driving gear 311 to rotate. The driving gear 311 drives the stirring shaft 21 to rotate through the driven gear 211, and the stirring shaft 21 drives the stirring blade 22 to rotate. The surface of the stirring blade 22 facing the direction of its own rotation will continue to collide with the cleaning water, and the surface of the stirring blade 22 away from the direction of its own rotation is difficult to contact with the cleaning water, resulting in the surface of the stirring blade 22 away from the direction of its own rotation cannot be cleaned. By setting the second driving structure 32, the first linear driver 324 first drives the mounting block 322 to move from the guide rod 3231 The mounting block 322 moves from one end to the other end, and the transmission rack 321 moves from one end of the guide rod 3231 to the other end. The transmission rack 321 drives the stirring shaft 21 to rotate forward through the driven gear 211, and the stirring shaft 21 drives the stirring blade 22 to rotate forward. One side surface of the stirring blade 22 contacts with the cleaning water, and then the first linear drive 324 drives the mounting block 322 to return. The mounting block 322 drives the stirring shaft 21 to reverse through the transmission rack 321 and the driven gear 211, and the stirring shaft 21 drives the stirring blade 22 to reverse. The other side surface of the stirring blade 22 contacts with the cleaning water, thereby achieving the cleaning of the surfaces on both sides of the stirring blade 22.

[0041] Reference Figure 4 and Figure 6As shown in the figure: The driving mechanism 3 further includes a switching structure 33. The switching structure 33 is arranged between the first driving structure 31 and the second driving structure 32. The switching structure 33 includes a U-shaped frame 331, a first connection structure 332, a second connection structure 333, and a synchronous driving structure 334. The U-shaped frame 331 covers the upper parts of the first driving structure 31 and the second driving structure 32, and the U-shaped frame 331 is connected to the cover body 12. The first installation groove and the second installation groove are symmetrically formed on the U-shaped frame 331. The first connection structure 332 is arranged in the first installation groove. The first connection structure 332 connects the first driving structure 31 and the U-shaped frame 331. The first connection structure 332 includes a first U-shaped plate 3321, a first guiding cross bar 3322, and a first moving block 3323. The first U-shaped plate 3321 is installed in the first installation groove. The two ends of the first guiding cross bar 3322 are respectively connected to the two ends of the first U-shaped plate 3321. The first moving block 3323 is slidably arranged on the first guiding cross bar 3322. The first rotary driver 312 is installed on the first moving block 3323. The second connection structure 333 is arranged in the second installation groove. The second connection structure 333 connects the second driving structure 32 and the U-shaped frame 331. The second connection structure 333 includes a second U-shaped plate 3331, a second guiding cross bar 3332, and a second moving block 3333. The second U-shaped plate 3331 is installed in the second installation groove. The two ends of the second guiding cross bar 3332 are respectively connected to the two ends of the second U-shaped plate 3331, and the axis of the second guiding cross bar 3332 is collinear with the axis of the first guiding cross bar 3322. The second moving block 3333 is slidably arranged on the second guiding cross bar 3332. The middle part of the mounting plate 3334 is connected to the second moving block 3333. The first linear driver 324 is arranged at one end of the mounting plate 3334. One end of the guiding rod 3231 is fixedly connected to the other end of the mounting plate 3334. The synchronous driving structure 334 is arranged on one side of the U-shaped frame 331. The synchronous driving structure 334 is used to drive the first driving structure 31 and the second driving structure 32 to move synchronously. The synchronous driving structure 334 includes two connection blocks 3341 and a first screw rod 3342. The two connection blocks 3341 are respectively connected to the first moving block 3323 and the second moving block 3333. The first screw rod 3342 is in transmission connection with the two connection blocks 3341.

[0042] When the first driving structure 31 works, the driving gear 311 drives the driven gear 211 to rotate. The driven gear 211 drives the transmission rack 321 to move. When the second driving structure 32 works, the movement of the transmission rack 321 is transmitted to the driving gear 311 through the driven gear 211. Therefore, a certain distance needs to be maintained between the first driving structure 31 and the second driving structure and the driven gear 211. By setting the switching structure 33, when the stirring blade 22 stirs the raw materials, the first screw 3342 rotates forward, and the two connecting blocks 3341 drive the first moving block 3323 and the second moving block 3333 to move in one direction respectively. The first moving block 3323 drives the first rotary driver 312 to move towards the driven gear 211, and the driving gear 311 meshes with the driven gear 211, so that the stirring blade 22 continuously rotates along one reverse direction. When the self-cleaning mechanism works, the first screw 3342 rotates reversely, the first moving block 3323 and the second moving block 3333 move in opposite directions, the driving gear 311 disengages from the driven gear 211, and the transmission rack 321 meshes with the driven gear 211, so that the stirring blade 22 swings reciprocally, thus avoiding the problem of mutual interference between the first driving structure 31 and the second driving structure 32, and enabling the stirring structure 2 to have two working modes.

[0043] Refer to Figure 3 、 Figure 7 and Figure 8 As shown in: The automatic cleaning mechanism 4 further includes a first installation bin 42, a second installation bin 43, a first opening and closing mechanism 44 and a rotating mechanism 46; The first installation bin 42 is arranged at the bottom of the tank body 11; The second installation bin 43 is arranged at the bottom of the first installation bin 42; The first opening and closing mechanism 44 is arranged in the first installation bin 42, and the first opening and closing mechanism 44 is used to drive a plurality of high-pressure water pipes 41 away from or close to the cleaning window 111; The rotating mechanism 46 is arranged in the second installation bin 43, and the rotating mechanism 46 is used to drive a plurality of high-pressure water pipes 41 to rotate, so that the nozzles 411 of the high-pressure water pipes 41 face away from the inner side of the tank body 11.

[0044] The nozzles 411 of the high-pressure water pipes 41 face the inside of the tank body 11. When enzymatic hydrolysis is carried out in the tank body 11, raw materials may enter the high-pressure water pipes 41 from the nozzles 411. By setting the first opening and closing mechanism 44 and the rotating mechanism 46, before injecting raw materials into the tank body 11, the first opening and closing mechanism 44 works to separate a plurality of high-pressure water pipes 41 from the tank body 11, then the rotating mechanism 46 works to rotate a plurality of high-pressure water pipes 41 simultaneously, the nozzles 411 of the high-pressure water pipes 41 face away from the tank body 11, and then the first opening and closing mechanism 44 works again to connect a plurality of high-pressure water pipes 41 to the tank body 11, so that the cleaning window 111 on the tank body 11 is blocked, thus avoiding raw materials from entering the high-pressure water pipes 41 from the nozzles 411.

[0045] Refer toFigure 7 and Figure 8 As shown in Figure 8 , a strip-shaped sealing block 412 is further provided on the high-pressure water pipe 41, and the strip-shaped sealing block 412 is arranged along the generatrix of the high-pressure water pipe 41.

[0046] The side wall of the tank body 11 has a certain thickness. When the high-pressure water pipe 41 abuts against the tank body 11, there is a certain distance between the inner side wall surface of the tank body 11 and the outer surface of the high-pressure water pipe 41. Therefore, there is still a cavity at the cleaning window 111 of the tank body 11, and part of the prepared polypeptide may remain in the cavity. When cleaning, the first opening and closing mechanism 44 and the rotating mechanism 46 turn the nozzle 411 on the high-pressure water pipe 41 towards the inside of the tank body 11 again. During this process, the prepared polypeptide in the cavity will flow to the outside of the tank body 11. By setting the strip-shaped sealing block 412, when preparing the polypeptide, the strip-shaped sealing block 412 fits into the cleaning window 111 to fill the cavity there, and at the same time makes the inner side wall surface of the tank body 11 form a complete ring, avoiding interference with the stirring blade 22, thereby preventing part of the prepared polypeptide from flowing to the outside of the tank body 11.

[0047] Refer to Figure 8 and Figure 9 As shown in Figure 9 , the first opening and closing mechanism 44 includes a fixed column 441, a driving plate 442, a plurality of driving arm assemblies 443 and a second linear driver 444. The fixed column 441 is arranged at the bottom of the tank body 11, and the axis of the fixed column 441 is collinear with the central axis of the tank body 11; the driving plate 442 is connected to the fixed column 441 through a bearing, the axis of the driving plate 442 is collinear with the axis of the fixed column 441, and the driving plate 442 has a plurality of corners; a plurality of driving arm assemblies 443 are respectively arranged at a plurality of corners of the driving plate 442, and a plurality of driving arm assemblies 443 connect the driving plate 442 with the lower ends of a plurality of high-pressure water pipes 41. The driving arm assembly 443 includes a first driving arm 4431, a second driving arm 4432 and a limit sleeve 4433. One end of the first driving arm 4431 is pivotally connected to one end of the second driving arm 4432, the other end of the first driving arm 4431 is pivotally connected to a corner of the driving plate 442, the other end of the second driving arm 4432 is connected to the lower end of the high-pressure water pipe 41 through a bearing, the limit sleeve 4433 is fixed at the lower end of the tank body 11, and the first driving arm 4431 is slidably arranged inside the limit sleeve 4433; the second linear driver 444 is arranged on one side of the driving plate 442, and the second linear driver 444 is used to push the driving plate 442 to rotate around the axis of the fixed column 441.

[0048] When it is necessary to control the high-pressure water pipe 41 to move away from the tank body 11, the second linear driver 444 pushes the driving plate 442, and the driving plate 442 rotates forward around the axis of the fixed column 441. The driving plate 442 pushes a plurality of first driving arms 4431 to move, and a plurality of first driving arms 4431 respectively push a plurality of second driving arms 4432 to move. A plurality of second driving arms 4432 respectively push a plurality of high-pressure water pipes 41 away from the tank body 11. When it is necessary to control the high-pressure water pipe 41 to closely adhere to the tank body 11, the second linear driver 444 pulls the driving plate 442 to rotate reversely around the axis of the fixed column 441. The driving plate 442 drives a plurality of first driving arms 4431 to move, and a plurality of first driving arms 4431 respectively exert a force on a plurality of second driving arms 4432 towards the central axis of the tank body 11, so as to simultaneously control the movement of a plurality of high-pressure water pipes 41.

[0049] Refer to Figure 3 and Figure 10 As shown: The automatic cleaning mechanism 4 further includes a second opening and closing mechanism 45. The second opening and closing mechanism 45 is arranged inside the cover body 12. The structure of the second opening and closing mechanism 45 is the same as that of the first opening and closing mechanism 44, and the second opening and closing mechanism 45 is connected to the upper ends of a plurality of high-pressure water pipes 41.

[0050] The length of the high-pressure water pipe 41 is relatively long. The first opening and closing mechanism 44 exerts a pulling force on the lower end of the high-pressure water pipe 41 towards the central axis of the tank body 11. The acting force between the lower end of the high-pressure water pipe 41 and the tank body 11 is relatively large, while the acting force between the upper end of the high-pressure water pipe 41 and the tank body 11 is relatively small, which may cause a gap to appear between the upper end of the high-pressure water pipe 41 and the cleaning window 111 of the tank body 11. By setting the second opening and closing mechanism 45, the second opening and closing mechanism 45 and the first opening and closing mechanism 44 move synchronously, and the acting forces received by the upper and lower ends of the high-pressure water pipe 41 are the same, thereby avoiding a gap between the high-pressure water pipe 41 and the tank body 11.

[0051] Refer to Figure 8 and Figure 11 As shown: The rotating mechanism 46 includes a plurality of driven wheels 461, a synchronous transmission belt 462, a tensioning structure 463 and a third driving structure 464; a plurality of driven wheels 461 respectively correspond to a plurality of high-pressure water pipes 41, and the driven gear 211 is installed at the lower end of the high-pressure water pipe 41; the synchronous transmission belt 462 is connected to a plurality of driven wheels 461; the tensioning structure 463 is arranged in the middle of a plurality of driven wheels 461, and the tensioning structure 463 keeps the synchronous transmission belt 462 in a tensioned state; the third driving structure 464 is arranged in the second installation bin 43, and the third driving structure 464 is used to drive a driven wheel 461 to rotate. The third driving structure 464 includes a driving wheel 4641 and a second rotating driver 4642. The driving wheel 4641 is tangent to the driven wheel 461, and the second rotating driver 4642 is used to drive the driving wheel 4641 to rotate.

[0052] When several high-pressure water pipes 41 are all far away from the tank body 11, the distance between several driven wheels 461 increases. The tensioning structure 463 adjusts the circulation path of the synchronous drive belt 462 to keep the tension degree of the synchronous drive belt 462 unchanged. The second rotary driver 4642 drives the driving wheel 4641 to rotate. The driving wheel 4641 drives one driven wheel 461 to rotate. The driven wheel 461 drives the synchronous drive belt 462 to move synchronously. The synchronous drive belt 462 drives the remaining driven wheels 461 to rotate. Several driven wheels 461 thus rotate synchronously, and several driven wheels 461 respectively drive several high-pressure water pipes 41 to rotate, so as to realize simultaneous control of several high-pressure water pipes 41 to adjust their own postures.

[0053] Refer to Figure 8 、 Figure 11 and Figure 12 As shown in: The rotating mechanism 46 further includes a synchronous moving structure 465. The synchronous moving structure 465 connects the third driving structure 464 with the driving arm assembly 443. The synchronous moving structure 465 includes a first rectangular frame 4651, a third guiding cross bar 4652, a third moving block 4653, a connecting plate 4654 and a connecting column 4655. The first rectangular frame 4651 is installed at the bottom of the first installation bin 42. The two ends of the third guiding cross bar 4652 are respectively connected with the two ends of the first rectangular frame 4651, and the direction of the axis of the third guiding cross bar 4652 is parallel to the moving direction of the first driving arm 4431. The third moving block 4653 is slidably arranged on the third guiding cross bar 4652. The connecting plate 4654 connects the third moving block 4653 with the second rotary driver 4642. The connecting column 4655 connects the second driving arm 4432 with the third moving block 4653.

[0054] Since the driven wheel 461 will move along with the high-pressure water pipe 41, the third driving structure 464 also needs to move along with the driven wheel 461 so that the power of the driving wheel 4641 can be transmitted to the driven wheel 461. Therefore, the synchronous moving structure 465 is provided. When the second driving arm 4432 drives the high-pressure water pipe 41 to move, the second driving arm 4432 drives the third moving block 4653 to move along the third guiding cross bar 4652 through the connecting column 4655. The third moving block 4653 drives the second rotary driver 4642 to move through the connecting plate 4654, so that the driving wheel 4641 and the driven wheel 461 move synchronously, so that the driving wheel 4641 and the driven wheel 461 are always in tight contact, and the power of the driving wheel 4641 is transmitted to the driven wheel 461.

[0055] Refer to Figure 8 and Figure 13As shown: The automatic cleaning mechanism 4 further includes a fixing mechanism 47. The fixing mechanism 47 is arranged at the bottom of the tank body 11. The fixing mechanism 47 includes two clamping plates 471 and a fourth driving structure 472. The two clamping plates 471 are respectively arranged at both ends of the driving plate 442. The fourth driving structure 472 is arranged between the two clamping plates 471. The fourth driving structure 472 includes a second rectangular frame 4721, a second screw rod 4722, a fourth guiding cross bar 4723, two fourth moving blocks 4724 and a third rotary driver 4725. Both ends of the second rectangular frame 4721 are connected to the bottom of the tank body 11. Both ends of the second screw rod 4722 are respectively connected to both ends of the second rectangular frame 4721, and the second screw rod 4722 is a double-headed screw rod. The fourth guiding cross bar 4723 is arranged in parallel on one side of the second screw rod 4722. Both ends of the fourth guiding cross bar 4723 are respectively connected to both ends of the second rectangular frame 4721. The two fourth moving blocks 4724 are respectively arranged at both ends of the second screw rod 4722, and the two fourth moving blocks 4724 are respectively connected to the two clamping plates 471. The third rotary driver 4725 is used to drive the second screw rod 4722 to rotate.

[0056] When the stirring structure 2 is performing stirring work and cleaning work, vibrations will be generated. The vibrations may cause the first opening and closing mechanism 44 to become loose, resulting in the separation of the high-pressure water pipe 41 from the tank body 11. By setting the fixing mechanism 47, the third rotary driver 4725 drives the second screw rod 4722 to rotate. The second screw rod 4722 drives the two fourth moving blocks 4724 to approach each other. The two fourth moving blocks 4724 respectively drive the two clamping plates 471 to approach each other. The two clamping plates 471 respectively abut against two opposite sides of the driving plate 442, making the driving plate 442 unable to rotate, thereby preventing the high-pressure water pipe 41 from separating from the tank body 11 under the influence of vibrations.

[0057] The above embodiments only represent one or several implementation manners of the present invention. The description is relatively specific and detailed, but it cannot be understood as a limitation on the scope of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present invention, several deformations and improvements can still be made, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims

1. An enzymatic hydrolysis furnace for polypeptide preparation that can be automatically cleaned, characterized in that: It comprises an enzymatic hydrolysis furnace body (1), a stirring structure (2), a driving mechanism (3) and an automatic cleaning mechanism (4); The enzymatic hydrolysis furnace body (1) comprises a tank body (11) and a cover body (12); a plurality of cleaning windows (111) are provided in a circular array on the tank body (11); the plurality of cleaning windows (111) penetrate the side wall of the tank body (11); and the cover body (12) is provided on the upper end of the tank body (11); The stirring structure (2) is arranged inside the tank body (11); The driving mechanism (3) is arranged at the upper end of the cover body (12), and the driving mechanism (3) is used to drive the stirring structure (2) to move; The automatic cleaning mechanism (4) is arranged outside the tank body (11), and the automatic cleaning mechanism (4) comprises a plurality of high-pressure water pipes (41), the plurality of high-pressure water pipes (41) respectively corresponding to the plurality of cleaning windows (111), the high-pressure water pipe (41) comprising a cleaning portion and a water supply portion, the cleaning portion being closely attached to the cleaning window (111), the cleaning portion being provided with a plurality of nozzles (411), the plurality of nozzles (411) all facing the inside of the tank body (11), and the plurality of nozzles (411) being arranged along a busbar of the high-pressure water pipe (41), the water supply portion being located at the lower end of the cleaning portion, and the water supply portion being externally connected to a pressurized water supply device; The driving mechanism (3) comprises a first driving structure (31) and a second driving structure (32); The first driving structure (31) is arranged on one side above the cover body (12), and the first driving structure (31) is used to drive the stirring structure (2) to stir various raw materials in the tank body (11); The second driving structure (32) is arranged on the other side above the cover body (12), and the second driving structure (32) is used to drive the stirring structure (2) to clean the inner wall of the tank body (11); The driving mechanism (3) further comprises a switching structure (33), the switching structure (33) being arranged between the first driving structure (31) and the second driving structure (32), the switching structure (33) comprising a U-shaped frame (331), a first connecting structure (332), a second connecting structure (333) and a synchronous driving structure (334); The U-shaped frame (331) is disposed above the first drive structure (31) and the second drive structure (32), and the U-shaped frame (331) is connected to the cover body (12). The U-shaped frame (331) is symmetrically provided with a first mounting groove and a second mounting groove; The first connection structure (332) is arranged in the first installation groove, and the first connection structure (332) connects the first driving structure (31) and the U-shaped frame (331); The second connection structure (333) is arranged in the second installation groove, and the second connection structure (333) connects the second driving structure (32) and the U-shaped frame (331); The synchronous driving structure (334) is arranged on one side of the U-shaped frame (331), and the synchronous driving structure (334) is used to drive the first driving structure (31) and the second driving structure (32) to move synchronously.

2. The automatic cleaning enzymolysis furnace for polypeptide preparation according to claim 1, characterized in that: The automatic cleaning mechanism (4) further comprises a first installation chamber (42), a second installation chamber (43), a first opening and closing mechanism (44) and a rotating mechanism (46); The first installation bin (42) is arranged at the bottom of the tank body (11); The second installation bin (43) is arranged at the bottom of the first installation bin (42); The first opening and closing mechanism (44) is disposed in the first installation compartment (42), and the first opening and closing mechanism (44) is used to drive the plurality of high-pressure water pipes (41) away from the cleaning window (111) or to be close to the cleaning window (111); The rotating mechanism (46) is arranged in the second installation chamber (43), and the rotating mechanism (46) is used to drive the plurality of high-pressure water pipes (41) to rotate so that the nozzles (411) of the high-pressure water pipes (41) face away from the inner side of the tank body (11).

3. The automatic cleaning enzymolysis furnace for polypeptide preparation according to claim 1, characterized in that: A strip-shaped sealing block (412) is also provided on the high-pressure water pipe (41), and the strip-shaped sealing block (412) is provided along the busbar of the high-pressure water pipe (41).

4. The automatic cleaning enzymolysis furnace for polypeptide preparation according to claim 2, characterized in that: The first opening and closing mechanism (44) comprises a fixing column (441), a driving plate (442), a plurality of driving arm assemblies (443) and a second linear drive (444). The fixing column (441) is arranged at the bottom of the tank body (11), and the axis of the fixing column (441) is colinear with the central axis of the tank body (11); The driving plate (442) is connected to the fixing column (441) via a bearing, the axis of the driving plate (442) is colinear with the axis of the fixing column (441), and the driving plate (442) has a plurality of corners; A plurality of driving arm assemblies (443) are respectively arranged at a plurality of corners of the driving plate (442), and the plurality of driving arm assemblies (443) connect the driving plate (442) and the lower ends of a plurality of high-pressure water pipes (41); The second linear driver (444) is arranged on one side of the driving plate (442), and the second linear driver (444) is used to drive the driving plate (442) to rotate around the axis of the fixing column (441).

5. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 2, characterized in that: The automatic cleaning mechanism (4) further comprises a second opening and closing mechanism (45), which is arranged inside the cover body (12), the structure of the second opening and closing mechanism (45) is the same as that of the first opening and closing mechanism (44), and the second opening and closing mechanism (45) is connected to the upper ends of a plurality of high-pressure water pipes (41).

6. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 2, characterized in that: The rotating mechanism (46) comprises a plurality of driven wheels (461), a synchronous transmission belt (462), a tensioning structure (463) and a third driving structure (464); A plurality of driven wheels (461) respectively correspond to a plurality of high-pressure water pipes (41), and a driven gear (211) is installed at the lower end of the high-pressure water pipe (41); A synchronous transmission belt (462) is connected to a plurality of driven wheels (461); A tensioning structure (463) is disposed in the middle of the plurality of driven wheels (461), and the tensioning structure (463) keeps the synchronous transmission belt (462) in a tensioned state; The third driving structure (464) is arranged in the second installation chamber (43), and the third driving structure (464) is used to drive a driven wheel (461) to rotate.

7. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 6, characterized in that: The rotating mechanism (46) further comprises a synchronous moving structure (465), wherein the synchronous moving structure (465) connects the third driving structure (464) and the driving arm assembly (443).

8. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 5, characterized in that: The automatic cleaning mechanism (4) further comprises a fixing mechanism (47), wherein the fixing mechanism (47) is arranged at the bottom of the tank body (11), and the fixing mechanism (47) comprises two clamping plates (471) and a fourth driving structure (472); Two clamping plates (471) are respectively arranged at two ends of the driving plate (442); The fourth driving structure (472) is arranged outside the two clamping plates (471).

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